10-Day Italy Self-Drive Road Trip With Itinerary from Perugia traveling north to Florence, Venice, Verona, Milan, and Pisa

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Porta di Venere, from the Roman era, made of white travertine, with its three arches and the two towers of Properzio in Perugia, Italy
Photo of Christmas in Assisi, Saint Francis Basilica with the Christmas Crib. Province of Perugia, Umbria, Italy.
10-Day Italy Self-Drive Road Trip With Itinerary from Perugia traveling north to Florence, Venice, Verona, Milan, and Pisa
10-Day Italy Self-Drive Road Trip With Itinerary from Perugia traveling north to Florence, Venice, Verona, Milan, and Pisa
10-Day Italy Self-Drive Road Trip With Itinerary from Perugia traveling north to Florence, Venice, Verona, Milan, and Pisa
10-Day Italy Self-Drive Road Trip With Itinerary from Perugia traveling north to Florence, Venice, Verona, Milan, and Pisa
10-Day Italy Self-Drive Road Trip With Itinerary from Perugia traveling north to Florence, Venice, Verona, Milan, and Pisa
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Explore the best of Italy on a remarkable 10-day road trip! Combine exploration with relaxation on a self-drive tour featuring Perugia, Florence, Bologna, Venice, Verona, Valeggio sul Mincio, Milan, Genoa, Pisa, and Siena.

This perfectly planned road trip itinerary takes you through some of the best places to see in Italy. You will spend 2 nights in Perugia, 2 nights in Florence, 1 night in Venice, 1 night in Verona, 2 nights in Milan, and 1 night in Pisa. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Perugia, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Piazza San Marco and Rialto Bridge are just a couple of the bucket-list attractions that await your discovery.

As you hit the open road and drive through Perugia, Florence, Bologna, Venice, Verona, Valeggio sul Mincio, Milan, Genoa, Pisa, and Siena, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.

Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!

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Driver’s age is 30 - 65
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Day1

Day 1

  • Perugia - Arrival day
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  • Etruscan Arch
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Welcome to Perugia, the perfect starting point for your road trip in Italy! Pick up your rental car and let the adventure begin. You will spend 1 night discovering what to see in Perugia before embarking on the next leg of your journey.

Perugia is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Etruscan Arch. Taking a stroll in the city center is a great alternative. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Find your way to your hotel in Perugia. We recommend choosing a hotel in a central location for easy exploring. Check-in typically starts between 2 and 4 PM at hotels in Italy. Settle in and make plans for the evening.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Perugia, it's often a good idea to reserve a table in advance.

Savor the flavors at Ristorante Settimo Sigillo, a top pick for dinner tonight. Alternatively, Caffè Baglioni beckons with its unique menu offerings. Also, consider Bar Pellas. With its consistent customer satisfaction, it’s an excellent option for dining in Perugia tonight.

To truly maximize your evening out, consider visiting Tommi Bar after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to Valentina, another bar with an inviting ambiance. Similarly, Caffe Dal Perugino also offers a great atmosphere, ensuring a night filled with enjoyment and relaxation.

Raise a toast to the start of your 10-day road trip in Italy!

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Day2

Day 2

  • Perugia
  • Florence
  • More

Drive 252 km, 3 hours 32 min

  • Piazza IV Novembre
  • National Gallery
  • Rocca Paolina
  • Borgo di Rasiglia
  • More

On day 2 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 2 destinations, including Perugia and Rasiglia. When you’re not sightseeing, take time to relax at your chosen hotel in Florence, where you’ll be staying for 2 nights.

One of the most curiosity-inducing attractions included on the itinerary is Piazza Iv Novembre. This romantic public square will help you start your sightseeing on top. Then, take a leisurely stroll to National Gallery and learn what makes this eye-catching art gallery unique.

Throughout the day, make sure to take breaks to appreciate the surroundings. Next up, visit the locally appreciated Rocca Paolina.

When you’re ready to jump back into the car and say goodbye to Perugia, you’ll hit the road in the direction of Rasiglia. This drive usually takes around 51 min.

Enjoy sightseeing at your own pace and allow yourself time to explore the beautiful surroundings. Take your self-guided tour to Borgo Di Rasiglia, a worthwhile historical landmark that everyone visiting Rasiglia should see.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Florence. Florence offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Florence. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Have a memorable dining experience in Florence by booking a table at Enoteca Pinchiorri, a 3-star Michelin restaurant presenting an exceptional italian contemporary menu. For a different culinary experience in Florence, Santa Elisabetta shines as one of the top destinations, known for its delicious creative and mediterranean cuisine. This 2-star Michelin-awardee consistently earns high praises, making it a must-visit addition to your holiday experience. If you're looking for an alternative, Il Palagio is known as a top local spot in Florence for its delicious italian contemporary cuisine. This 1-star Michelin awardee is a highly recommended choice for an unforgettable meal.

After enjoying a fulfilling meal, continue your evening at Manifattura, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, Se·sto On Arno Rooftop Bar offers a welcoming atmosphere for easing into the nightlife. Similarly, Il Vinile provides an excellent environment for a relaxed and enjoyable evening.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in Italy.

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Day3

Day 3

  • Florence
  • More

Drive 5 km, 1 hour 20 min

  • piazzale Michelangelo
  • Uffizi Gallery
  • Ponte Vecchio
  • piazza della Signoria
  • Galleria dell'Accademia
  • More

Day 3 of your road trip across Italy promises a magnificent time exploring what to see in Florence. You have 1 night left in Florence. Take the opportunity to experience more of the best attractions and activities in the city.

Visiting Piazzale Michelangelo is always a good idea. This astonishing observation deck is a place that is appreciated by travelers and locals alike. Next, immerse yourself in the instagrammable wonders of Uffizi Gallery, a must-see art gallery in the city.

Consider stopping for a small bite to eat or a drink at a local eatery to keep your energy going. When you’re ready, continue your discovery with a visit to Ponte Vecchio. This iconic historical landmark offers an enriching experience. For a change of pace, head to Piazza Della Signoria, where you can take in romantic features. Conclude your self-guided sightseeing tour with a visit to Galleria Dell'accademia These sights offer a fulfilling end to a perfect day.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Florence, it's often a good idea to reserve a table in advance.

Have a fantastic dining experience at Ditta Artigianale, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Trattoria Da Burde offers an enticing alternative with its varied menu. Additionally, Casa Toscana is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Florence.

Cap off your dinner by heading to Bar 50 Rosso, ideal for a leisurely evening with a drink in hand. Bitter Bar is another bar that offers an enjoyable setting. Similarly, Archea Brewery is also a popular place to go on a night out, perfect for relaxing and socializing.

Say good night to Florence and look forward to another great day of your road trip in Italy!

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Day4

Day 4

  • Florence
  • Bologna
  • Venice
  • More

Drive 261 km, 3 hours 41 min

  • Cathedral of Santa Maria del Fiore
  • Brunelleschi's dome
  • Central Market
  • Two Towers
  • Piazza Maggiore
  • More

Dive into day 4 of your remarkable road trip in Italy. Today you'll explore 2 destinations, including Florence and Bologna. At the end of the day, you’ll unwind at one of the finest accommodations in Venice, where you'll spend 1 night.

Start your day at Cathedral Of Santa Maria Del Fiore. This visually striking church is an extraordinary place to see in Florence. Then, wander over to Brunelleschi's Dome. If history-steeped sites excite you, this monument will be right up your alley. Nearby, you’ll also find Central Market. This visually striking food market is a favorite among visitors.

Fasten your seatbelt and make your way to your next stop — Bologna, home to many well-known sights in the region. Keep in mind that your travel time from Florence to Bologna may take around 1 hour 29 min without traffic disruptions. Upon arrival in Bologna, we highly recommend checking out some of the top attractions.

For a more meaningful self-guided tour of the city's best attractions, visit Two Towers, a notable monument that is sure to impress. Take in the surroundings and enjoy the freedom of exploring at your own pace before you continue your journey. Next, head to Piazza Maggiore and admire its visually striking features.

When you’re done exploring for the day, you’ll drive to your hotel in Venice. Check in and relax before you head out to tour the city.

After a day of adventure, treat yourself to an exquisite dinner at one of Venice's best restaurants.

Enjoy an outstanding dining experience at Local, a 1-star Michelin restaurant offering an exceptional contemporary menu. Alternatively, if you're in the mood for something different, consider the nearby 1-star Michelin-awardee, Wistèria, known for its delicious contemporary and venetian cuisine. Another highly-recommended place to eat in Venice is Quadri, a renowned restaurant with a 1-star Guide Michelin recognition and a delicious modern menu.

Unwind after your meal by stepping into Al Parlamento. This venue is celebrated for its extensive drink selections and cozy vibes. Alternatively, The Caffe Rosso offers a dynamic and energetic atmosphere for a glass or two. Don’t overlook Adagio, another top-rated bar in the area.

Relax and recharge in preparation for another adventurous day in Italy!

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Day5

Day 5

  • Venice
  • Verona
  • More

Drive 122 km, 1 hour 38 min

  • Rialto Bridge
  • Piazza San Marco
  • St Mark's Basilica
  • Doge's Palace
  • Bridge of Sighs
  • More

Experience an unparalleled adventure on day 5 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 place, which are Venice. At the end of the day, you will retreat to the hotel of your choice in Verona, where will spend 1 night.

Awaiting your discovery is the world-famous Rialto Bridge, a romantic historical landmark in Venice. Next, go to Piazza San Marco.

After visiting Rialto Bridge and Piazza San Marco, have a stroll along Venice's streets and take in the local charm. Continue your sightseeing by heading to St Mark's Basilica. This enchanting church offers a unique experience. Doge's Palace is another noteworthy attraction worthwhile a visit. End your self-guided sightseeing tour on top with a visit to Bridge Of Sighs, one of the most visually striking places to visit in Venice.

At the end of the day, you will drive to Verona, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Verona, it's often a good idea to reserve a table in advance.

Experience a harmony of flavors at Osteria Mondo d'Oro in Verona by securing a reservation in advance. Known for its Bib Gourmand status, Osteria Mondo d'Oro offers a delightful variety of dishes highlighting its delicious italian and seasonal menu. If you're seeking an alternative culinary experience, be sure to explore Casa Perbellini 12 Apostoli, a highly recommended restaurant known for its enticing creative and contemporary cuisine. This popular 2-star Michelin-awarded venue consistently exceeds expectations, ensuring a memorable holiday experience. Ready for another culinary adventure? Indulge your senses at Il Desco, a highly acclaimed restaurant celebrated for its exceptional italian contemporary menu.

Keep the excitement of the evening going by visiting a bar or two. Archivio is an excellent place to start. You could also check out La Segreteria Café, offering a different kind of charm. A last recommendation for the day is Grande Giove Cocktail Bar. This bar promises an enjoyable experience with tasty drinks and a vibrant setting.

Relax and look forward to more memorable moments to come!

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Day6

Day 6

  • Verona
  • Valeggio sul Mincio
  • Milan
  • More

Drive 182 km, 3 hours 8 min

  • Verona Arena
  • Parco Giardino Sigurtà
  • Gardaland Resort
  • More

Your itinerary for day 6 of your road trip in Italy includes 3 stops and features some of the highlights of Verona, Valeggio sul Mincio, and Ronchi. At the end of the day, enjoy the comforts of a top-rated hotel in Milan, where you'll spend 2 nights.

Make a stop at Verona Arena. This globally renowned stadium is a must-visit for travelers looking for a unique holiday experience.

Set your GPS to Valeggio sul Mincio and hit the road. Expect a journey of approximately 50 min without stops. Soak in the beautiful landscapes as you drive and look forward to exploring your next destination. Valeggio sul Mincio beckons with new experiences!

Savor the day by heading to Parco Giardino Sigurtà, a popular botanical garden that draws visitors from near and far.

Embrace the thrill of the open road as you wave goodbye to Valeggio sul Mincio and set your GPS to Ronchi. While on the road, immerse yourself in your favorite road trip tunes or sample the sounds from a local radio station. This car ride usually takes around 31 min. Upon reaching Ronchi, unwind, observe, and explore. The best things to do, see, and eat are waiting for you.

One of our top recommendations for your sightseeing is Gardaland Resort. Spend some time admiring the stunning features of the amusement park before you continue to your next stop.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Milan. Milan offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

Indulge in a memorable dining experience at one of Milan's most popular restaurants, and connect with friendly locals for a true cultural experience.

Treat yourself to an extraordinary dining experience at Enrico Bartolini al Mudec, a 3-star Michelin restaurant offering an incredible creative menu. Alternatively, if your taste buds call for something different, Seta by Antonio Guida is one of the best restaurants for international and contemporary cuisine in Milan. This 2-star Michelin-awardee earns consistently high praises from guests. We also recommend checking out the menu at Il Luogo Aimo e Nadia. As a top-rated establishment with 1 Michelin star, it is an ideal choice for italian contemporary and modern cuisine in the city.

After savoring a delicious meal, step into the vibrant nightlife at Nottingham Forest, where the evening is just getting started. In the same way, Armani/bamboo Bar offers a unique charm perfect for experiencing the local bar scene in Milan. Mag Cafe is another top-recommended bar that is sure to get you into the mood for some dancing and celebrating.

Get a good night's sleep and look forward to another great day on the road in Italy!

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Day7

Day 7

  • Milan
  • More

Drive 8 km, 1 hour 7 min

  • Piazza Gae Aulenti
  • Pinacoteca di Brera
  • Castello Sforzesco
  • Sempione Park
  • Arch of Peace
  • More

Day 7 of your road trip will take you to the best attractions Milan has to offer. Cherish the 1 night you have left in the city and use the provided itinerary to discover what to see in Milan.

Awaiting your discovery is the well-known Piazza Gae Aulenti, a breathtaking public square in Milan. Next, go to Pinacoteca Di Brera.

After visiting Piazza Gae Aulenti and Pinacoteca Di Brera, have a stroll along Milan's streets and take in the local charm. Continue your sightseeing by heading to Sforzesco Castle Art Library. This historic castle offers a unique experience. Parco Sempione is another noteworthy attraction worthwhile a visit. End your self-guided sightseeing tour on top with a visit to Arch Of Peace, one of the most breathtaking places to visit in Milan.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

Indulge in a memorable dining experience at one of Milan's most popular restaurants, and connect with friendly locals for a true cultural experience.

Make sure to reserve a table at Dessert Bar Milano, an iconic dining spot in Milan. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Radisson Blu Hotel Milan, a popular restaurant in Milan. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Ristorante Qui Si Mangia, a hidden gem nestled in Milan. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Extend your evening after a delightful meal by visiting Kilburn Cocktail Bar Milano, which offers the perfect atmosphere for a night out. Moreover, Bar Frida is another popular option for a drink or two. Likewise, The Friends Pub Milano also provides a great ambiance for reminiscing about the day and raising a toast to your vacation.

As the sun sets, rest up and recharge for the next leg of your road trip in Italy.

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Day8

Day 8

  • Milan
  • Genoa
  • Pisa
  • More

Drive 320 km, 4 hours 12 min

  • Galleria Vittorio Emanuele II
  • Duomo di Milano
  • Aquarium of Genoa
  • More

On day 8 of your road trip in Italy, your travel plans include 2 stops at the most scenic, wondrous, and interesting places in the region. Milan and Genoa are on today's agenda. In the evening, you’ll end up in Pisa, where you will stay for 1 night.

Galleria Vittorio Emanuele Ii brings Milan's character to life. This remarkable shopping mall is a highlight of any visit in the city. Then, enjoy Duomo Di Milano Museum, another history-steeped attraction that never fails to captivate visitors.

Embrace the thrill of the open road as you wave goodbye to Milan and set your GPS to Genoa. While on the road, immerse yourself in your favorite road trip tunes or sample the sounds from a local radio station. This car ride usually takes around 1 hour 58 min. Upon reaching Genoa, unwind, observe, and explore. The best things to do, see, and eat are waiting for you.

When you're ready for some sights, head to Aquarium Of Genoa, a famous aquarium in Genoa. Explore its breathtaking features at your own pace before you continue your journey.

When you’re done exploring for the day, you’ll drive to your hotel in Pisa. Check in and relax before you head out to tour the city.

Pisa is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Pisa.

Savor the flavors at Anima di Grano Pizzeria Napoletana Pisa Italy, a top pick for dinner tonight. Alternatively, il Mercante beckons with its unique menu offerings. Also, consider La Ghiotteria. With its consistent customer satisfaction, it’s an excellent option for dining in Pisa tonight.

Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, Jeffer Cocktails & Friends stands out as an excellent choice for a post-dinner cocktail. Alternatively, Le Parisien Wine Bar offers an ideal atmosphere to enjoy the pleasures of the night. Las Volta Cocktailbar is also a great option that provides a perfect setting for a relaxing evening.

Celebrate another amazing day of your road trip adventure in Italy!

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Day9

Day 9

  • Pisa
  • Siena
  • Perugia
  • More

Drive 235 km, 3 hours 35 min

  • Leaning Tower of Pisa
  • Piazza del Duomo, Pisa
  • Siena Cathedral
  • piazza del Campo
  • More

On day 9 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 2 destinations, including Pisa and Siena. When you’re not sightseeing, take time to relax at your chosen hotel in Perugia, where you’ll be staying for 1 night.

Let Leaning Tower Of Pisa set the tone for the day. Spend some time admiring this historic monument before continuing your journey. Piazza Del Duomo, Pisa is your next stop. This timeless public square is one of the best-rated sights in Pisa.

Siena’s wonders await as you prepare for another journey on the road, leaving the breathtaking surroundings of Pisa behind. This drive usually takes around 1 hour 50 min. Siena welcomes you with a multitude of unique vacation experiences.

Our first attraction recommendation in Siena is Siena Cathedral, a notable church that draws attention for its history-steeped features. Spend some time soaking in the atmosphere before continuing to Piazza Del Campo, a history-steeped public square that stands out in the city.

At the end of the day, you will drive to Perugia, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Perugia. Enjoy a relaxing evening as you savor delicious local cuisine.

Enjoy a delicious meal at La Taverna, a highly-rated dining destination in Perugia. If you're eager to try something different, consider Ristorante del Sole, another top spot with a tantalizing menu. You might also want to secure a reservation at Al Mangiar Bene. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Perugia this evening.

To truly maximize your evening out, consider visiting Caffè Fortebraccio after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to Caffe Del Banco, another bar with an inviting ambiance. Similarly, Dempsey's Perugia also offers a great atmosphere, ensuring a night filled with enjoyment and relaxation.

Savor another day of unforgettable experiences in Italy!

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Day10

Day 10

  • Perugia - Departure day
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  • Arco dei Gigli
  • More

Day 10 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Perugia before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, begin at Arco Dei Gigli. This worthwhile arco is a hotspot among locals.

Make the most of your final day in Italy by visiting Perugia’s iconic markets and shopping establishments. Secure the perfect souvenirs for your family and friends back home or buy yourself a remembrance of your amazing vacation.

Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Perugia.

You’ll then say farewell to Perugia. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!

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Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

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