10-Day Italy Self-Drive Road Trip With Itinerary from Perugia traveling north to Florence, Venice, Verona, Milan, and Pisa

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Experience the freedom of the open road in Italy as you embark on an unforgettable 10-day road trip! This experience caters to every traveler, featuring destinations like Perugia, Florence, Bologna, Venice, Verona, Valeggio sul Mincio, Milan, Genoa, Pisa, and Siena.

This perfectly planned road trip itinerary in Italy takes you through some of the best places to see in the country. You will spend 2 nights in Perugia, 2 nights in Florence, 1 night in Venice, 1 night in Verona, 2 nights in Milan, and 1 night in Pisa. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Perugia, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Piazza San Marco and Rialto Bridge are just a couple of the bucket-list attractions that await your discovery.

As you hit the open road and drive through Perugia, Florence, Bologna, Venice, Verona, Valeggio sul Mincio, Milan, Genoa, Pisa, and Siena, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.

Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!

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Itinerary summary

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Days
Destination
Attractions
Overnight
Day
City & Overnight
Attractions
Etruscan Arch
Piazza IV NovembreNational GalleryRocca PaolinaBorgo di RasigliaEtruscan Arch
piazzale MichelangeloUffizi GalleryPonte Vecchiopiazza della SignoriaGalleria dell'Accademia
Cathedral of Santa Maria del FioreBrunelleschi's domeCentral MarketTwo TowersPiazza MaggiorePonte Vecchio
Rialto BridgePiazza San MarcoSt Mark's BasilicaDoge's PalaceBridge of Sighs
Verona ArenaParco Giardino SigurtàGardaland Resort

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Day 1

Day 1

  • Perugia - Arrival day
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  • Etruscan Arch
  • More

Your road trip adventure in Italy begins as soon as you reach Perugia and pick up your car. You’ll stay in Perugia for 1 night and explore the best things to see and do, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.

Perugia is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Etruscan Arch or taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Make your way to your chosen hotel. Check-in typically starts between 2 and 4 PM in Perugia. Make yourself at home and enjoy some downtime before heading out again.

As dinnertime approaches, it's time to head out for a bite to eat in Perugia. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Have a fantastic dining experience at Ristorante Settimo Sigillo, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Caffè Baglioni offers an enticing alternative with its varied menu. Additionally, Bar Pellas is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Perugia.

Round off your dining experience by visiting Tommi Bar, a prime location for a drink. Alternatively, explore the distinctive characteristics of Valentina, a bar catering to every mood and preference. Caffe Dal Perugino likewise offers a unique atmosphere, perfect for a memorable night out.

Raise a toast to the start of your 10-day road trip in Italy!

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Day 2

Day 2

  • Perugia
  • Florence
  • More

Drive 252 km, 3 hours 32 min

  • Piazza IV Novembre
  • National Gallery
  • Rocca Paolina
  • Borgo di Rasiglia
  • Etruscan Arch
  • More

Experience an unparalleled adventure on day 2 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 2 vibrant destinations - Perugia and Rasiglia. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Florence. You will spend 2 nights here for some well-deserved relaxation.

Today, you'll explore some of the most beautiful places in Perugia, including a public square, an art gallery, and a historical landmark. Start your day with a visit to Piazza Iv Novembre. This underrated public square is a must-visit in the city. When you’re ready for your next discovery, continue to National Gallery, which may be one of the most instagrammable places you will experience today.

One of the best things about exploring Perugia on a self-guided tour is that you set the pace. There’s plenty of time for detours and discovering hidden gems. When you’re ready for your next stop, make your way to Rocca Paolina, one of the city’s most underrated historical landmark.

Fasten your seatbelt and make your way to your next stop. Rasiglia, home to many well-known sights in the region, is a lovely destination on today’s itinerary. Keep in mind that your travel time from Perugia to Rasiglia may take around 51 min without traffic disruptions. Upon arrival in Rasiglia, we highly recommend checking out some of the top attractions.

Borgo Di Rasiglia is an increasingly popular historical landmark we recommend making time to visit today. Discover its history-steeped features before continuing your self-guided tour.

After soaking up all the sights of today's itinerary, you'll be ready to hit the road in the direction of your accommodation in Florence. Florence offers plenty of top-rated hotels and other places to stay on any travel budget. Take some time to relax before you head out to explore.

As dinnertime approaches, it's time to head out for a bite to eat in Florence. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Treat yourself to an extraordinary dining experience at Enoteca Pinchiorri, a 3-star Michelin restaurant offering an incredible italian contemporary menu. Alternatively, if your taste buds call for something different, Santa Elisabetta is one of the best restaurants for creative and mediterranean cuisine in Florence. This 2-star Michelin-awardee earns consistently high praises from guests. We also recommend checking out the menu at Il Palagio. As a top-rated establishment with 1 Michelin star, it is an ideal choice for italian contemporary cuisine in the city.

Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, Manifattura stands out as an excellent choice for a post-dinner cocktail. Alternatively, Se·sto On Arno Rooftop Bar offers an ideal atmosphere to enjoy the pleasures of the night. Il Vinile is also a great option that provides a perfect setting for a relaxing evening.

Head back to your accommodation in Florence and get some rest in preparation for another magical day of your road trip in Italy!

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Day 3

Day 3

  • Florence
  • More

Drive 5 km, 1 hour 20 min

  • piazzale Michelangelo
  • Uffizi Gallery
  • Ponte Vecchio
  • piazza della Signoria
  • Galleria dell'Accademia
  • More

Day 3 offers a multitude of experiences. You will stay in Florence for 1 night more, offering you enough time to explore at a relaxed pace.

Today's adventure in Florence promises more breathtaking discoveries and enriching experiences! Begin at Piazzale Michelangelo. This history-steeped observation deck is a highlight of any visit in the city. Then, enjoy Uffizi Gallery, another picture-perfect attraction that never fails to captivate visitors. Next, head over to Ponte Vecchio, one of the city’s most iconic attractions, known for its symbolic features.

If you’re looking for more, spend time soaking in the atmosphere of Piazza Della Signoria. This visually striking public square is frequented by locals and tourists alike. To complete your memorable day, make sure to visit Galleria Dell'accademia, a well-known art gallery, and take a stroll around the area.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Florence. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Treat yourself to a delicious dinner at Ditta Artigianale, an excellent option for tonight's dining. Looking for something different? Trattoria Da Burde offers a tantalizing alternative with its diverse menu. And don’t miss Casa Toscana. With its reputation for pleasing customers, it’s a fantastic choice for tonight in Florence.

Following your dinner, dive into the local bar culture at Bar 50 Rosso. Enjoy this evening's relaxed ambiance with delightful drinks. Alternatively, go to Bitter Bar, the perfect place for those looking to experience the best of the nightlife. Similarly, Archea Brewery provides excellent drinks and a great atmosphere, ensuring a memorable night out.

Take some time to reflect on your day and savor another beautiful night in Italy.

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Day 4

Day 4

  • Florence
  • Bologna
  • Venice
  • More

Drive 261 km, 3 hours 41 min

  • Cathedral of Santa Maria del Fiore
  • Brunelleschi's dome
  • Central Market
  • Two Towers
  • Piazza Maggiore
  • Ponte Vecchio
  • More

On day 4 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Florence and Bologna. In the evening, you’ll end up in Venice, where you will stay for 1 night.

Get ready to discover some of the most iconic wonders in Florence, including a church, a monument, and a food market. Start your day at Cathedral Of Santa Maria Del Fiore. This romantic church is a famous place to see in Florence. Then, wander over to Brunelleschi's Dome. If UNESCO world heritage-listed sites excite you, this monument will be right up your alley. Nearby, you’ll also find Central Market. This instagrammable food market is a favorite among visitors.

Once you're ready to continue your road trip, it's time to buckle up and drive, eagerly anticipating your arrival in Bologna. This drive usually takes around 1 hour 29 min, without any stops or traffic disruptions.

Take your self-guided tour to Two Towers, a notable monument that everyone visiting Bologna should see. Enjoy sightseeing at your own pace and allow yourself time to explore the beautiful surroundings. Next, head to Piazza Maggiore. This romantic public square is one of the most famous attractions in the region.

When you’re done exploring for the day, you’ll drive to your hotel in Venice. Check in and spend some time relaxing before you head out to tour the city.

After a day of adventure, treat yourself to an exquisite dinner at one of Venice's best restaurants.

Discover the culinary delights of Venice by securing a reservation at Local. Esteemed for its 1-star Guide Michelin recognition, this restaurant offers a remarkable selection of contemporary cuisine. For an alternative dining experience, try Wistèria, renowned for its delicious contemporary and venetian dishes. This esteemed 1-star Michelin-recipient consistently impresses guests, making it a must-visit spot during your holiday. Craving more culinary excitement? Head to Quadri, a highly recommended local eatery celebrated for its mouthwatering modern menu. With its 1-star Michelin recognition, it offers an unforgettable dining adventure.

Extend your evening after a delightful meal by visiting Al Parlamento, which offers the perfect atmosphere for a night out. Moreover, The Caffe Rosso is another popular option for a drink or two. Likewise, Adagio also provides a great ambiance for reminiscing about the day and raising a toast to your vacation.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in Italy.

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Day 5

Day 5

  • Venice
  • Verona
  • More

Drive 122 km, 1 hour 38 min

  • Rialto Bridge
  • Piazza San Marco
  • St Mark's Basilica
  • Doge's Palace
  • Bridge of Sighs
  • More

Embark on another extraordinary experience on day 5 of your road trip in Italy. Today, you will make 1 stop and experience some of the highlights of Venice. At the end of the day, you will enjoy the comforts of a top-rated hotel in Verona, which will be your home away from home for 1 night.

Immerse yourself in Venice’s rich culture with today's sightseeing itinerary. Start your journey at Rialto Bridge. This visually striking historical landmark is sure to ignite your curiosity. Next, dive into the majestic features of Piazza San Marco, a must-visit public square in the city.

In between sights, stop by local stores, picturesque photo spots, and small eateries. When you’re ready for your next attraction, proceed to St Mark's Basilica, an interesting church. For a change of scene, check out Doge's Palace, known for its symbolic features.

At the end of the day, you will drive to Verona, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Verona. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Experience a taste of local culinary excellence while in Verona by securing a table at Osteria Mondo d'Oro. An esteemed Bib Gourmand restaurant, it features an exceptional italian and seasonal menu. For an alternative taste experience, visit Casa Perbellini 12 Apostoli, famous for its scrumptious creative and contemporary dishes. This 2-star Michelin venue consistently impresses guests, making it a standout addition to your holiday plans. Looking for another choice? Discover Il Desco, a local favorite celebrated for its exquisite italian contemporary cuisine in Verona. Located in the heart of the city, this 1-star Michelin restaurant is an ideal pick for italian contemporary cuisine lovers seeking top-notch culinary experiences.

Continue the enjoyment post-dinner at Archivio, a cherished local gathering spot renowned for its welcoming atmosphere. Similarly, La Segreteria Café offers a vibrant space for indulging in well-crafted drinks and engaging conversation. You may also want to check out Grande Giove Cocktail Bar. This bar is a favorite among both locals and visitors looking for a delightful evening out filled with laughter and fun.

Get a good night's sleep and look forward to another great day on the road in Italy!

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Day 6

Day 6

  • Verona
  • Valeggio sul Mincio
  • Milan
  • More

Drive 182 km, 3 hours 8 min

  • Verona Arena
  • Parco Giardino Sigurtà
  • Gardaland Resort
  • More

On day 6 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 3 destinations, Verona, Valeggio sul Mincio, and Ronchi. When you’re not sightseeing, take time to relax at your selected hotel in Milan, where you’ll be staying for 2 nights.

Enjoy the perfect balance of relaxation and exploration in Verona today. One of the most wondrous attractions included on the itinerary is Verona Arena. This history-steeped stadium will help you start your sightseeing on top.

Throughout the day, make sure to take breaks to appreciate the surroundings.

Embrace the thrill of the open road as you wave goodbye to Verona and set your GPS to Valeggio sul Mincio. While on the road, immerse yourself in your favorite road trip tunes or sample the sounds from a local radio station. This car ride usually takes around 50 min. Upon reaching Valeggio sul Mincio, unwind, observe, and explore. The best things to do, see, and eat are waiting for you.

Make your way to Parco Giardino Sigurtà, a popular botanical garden that draws attention for its serene features.

Embrace the thrill of the open road as you wave goodbye to Valeggio sul Mincio and set your GPS to Ronchi. While on the road, immerse yourself in your favorite road trip tunes or sample the sounds from a local radio station. This car ride usually takes around 31 min. Upon reaching Ronchi, unwind, observe, and explore. The best things to do, see, and eat are waiting for you.

Spend your afternoon discovering Gardaland Resort, a top-rated amusement park known for its picture-perfect features.

After soaking up all the sights of today's itinerary, you'll be ready to hit the road in the direction of your accommodation in Milan. Milan offers plenty of top-rated hotels and other places to stay on any travel budget. Take some time to relax before you head out to explore.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Milan. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Experience a symphony of flavors at Enrico Bartolini al Mudec in Milan by securing a reservation in advance. Renowned for its 3-star Michelin distinction, Enrico Bartolini al Mudec delights its guests with its exceptional variety of meals showcasing delicious creative cuisine. For a palate-pleasing alternative, make sure to dine at Seta by Antonio Guida, acclaimed for its delectable international and contemporary specialties. This local 2-star Michelin establishment consistently satisfies guests, ensuring an unforgettable holiday experience. Want to go on another culinary journey? Delight your senses at Il Luogo Aimo e Nadia, a top-rated restaurant known for its outstanding menu. Known as a top-rated 1-star Michelin establishment, it's a top choice for italian contemporary and modern cuisine in the city.

Following your dinner, dive into the local bar culture at Nottingham Forest. Enjoy this evening's relaxed ambiance with delightful drinks. Alternatively, go to Armani/bamboo Bar, the perfect place for those looking to experience the best of the nightlife. Similarly, Mag Cafe provides excellent drinks and a great atmosphere, ensuring a memorable night out.

Savor another day of unforgettable experiences in Italy!

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Day 7

Day 7

  • Milan
  • More

Drive 8 km, 1 hour 7 min

  • Piazza Gae Aulenti
  • Pinacoteca di Brera
  • Castello Sforzesco
  • Sempione Park
  • Arch of Peace
  • Duomo di Milano
  • More

Day 7 of your road trip will take you to the best attractions Milan has to offer. Cherish the 1 night you have left in Milan by discovering the best things there are to see and do in the city.

Whether you prefer a leisurely exploration or a more fast-paced adventure, this itinerary in Milan allows for both. Start by heading to Piazza Gae Aulenti. This locally renowned public square provides an insightful glimpse into the city's identity. Next, discover Pinacoteca Di Brera, a photogenic art gallery, promising a delightful encounter.

Continue your sightseeing with a visit to Sforzesco Castle Art Library, a famous castle. When you’re done, don’t forget to make a stop at the extraordinary Parco Sempione. Round off your day at Arch Of Peace, another gem in Milan with masterful features to discover.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

As you explore more of Milan, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Make sure to reserve a table at Dessert Bar Milano, an iconic dining spot in Milan. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Radisson Blu Hotel Milan, a popular restaurant in Milan. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Ristorante Qui Si Mangia, a hidden gem nestled in Milan. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Continue your lively evening at Kilburn Cocktail Bar Milano, a perfect place for winding down or revving up the night, depending on which mood you’re in. Bar Frida is another excellent bar that offers a great selection of drinks to suit any mood. If you prefer to go somewhere else, The Friends Pub Milano ensures a night out tailored to your taste.

Relax and reminisce about your day in Italy and look forward to more memorable moments to come!

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Day 8

Day 8

  • Milan
  • Genoa
  • Pisa
  • More

Drive 320 km, 4 hours 12 min

  • Galleria Vittorio Emanuele II
  • Duomo di Milano
  • Aquarium of Genoa
  • More

Dive into day 8 of your remarkable road trip in Italy. Today you will explore Milan and Genoa, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Pisa. You’ll stay here for 1 night.

Milan is home to plenty of attractions that offer a romantic, a stunning, a visually striking, a historically significant, and a detailed! Start at Galleria Vittorio Emanuele Ii, an astonishing shopping mall that is worthwhile a visit in the city.

Continue your road trip and head to your next destination, Genoa. This car ride takes around 1 hour 58 min.

Spend your afternoon discovering Aquarium Of Genoa, a top-rated aquarium known for its mesmerizing features.

When you’re done exploring for the day, you’ll drive to your hotel in Pisa. Check in and spend some time relaxing before you head out to tour the city.

Indulge in a memorable dining experience at one of Pisa's most popular restaurants, and connect with friendly locals for an authentic adventure.

Dine in style at Anima di Grano Pizzeria Napoletana Pisa Italy, a top recommendation for dinner tonight. Or, for a change of pace, il Mercante boasts a menu that's sure to impress. Also, be sure to check out La Ghiotteria. Known as a local hotspot, it’s a great choice for tonight in Pisa.

Continue your evening by exploring the vibrant nightlife scene at Jeffer Cocktails & Friends, a prime destination for a thrilling night out. Also, don’t forget to check out Le Parisien Wine Bar, a bar that offers unique local touches. Likewise, Las Volta Cocktailbar provides an excellent alternative for a fun evening.

Relax and reminisce about your day in Italy and look forward to more memorable moments to come!

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Day 9

Day 9

  • Pisa
  • Siena
  • Perugia
  • More

Drive 235 km, 3 hours 35 min

  • Leaning Tower of Pisa
  • Piazza del Duomo, Pisa
  • Siena Cathedral
  • piazza del Campo
  • More

Experience an unparalleled adventure on day 9 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 2 vibrant destinations - Pisa and Siena. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Perugia. You will spend 1 night here for some well-deserved relaxation.

Today’s agenda in Pisa includes a monument and a public square. Leaning Tower Of Pisa is must-visit monument and a great starting point for the day. Next, continue your journey to Piazza Del Duomo, Pisa, a world-famous public square, located just a leisurely stroll away.

When you’re ready to jump back into the car and say goodbye to Pisa, you’ll hit the road in the direction of Siena. This drive usually takes around 1 hour 50 min. When you arrive, enjoy some sightseeing.

One of our top recommendations for your sightseeing is Siena Cathedral. Spend some time admiring the enchanting features of the church before you continue to your next stop. Then, head to Piazza Del Campo. This extraordinary public square is a traveler-favorite in the city.

At the end of the day, you will drive to Perugia, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you explore more of Perugia, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Make sure to book a table at La Taverna, a popular restaurant in Perugia. This acclaimed restaurant and its mouthwatering dishes have earned the admiration of countless food lovers. Alternatively, experience a taste of Perugia at Ristorante del Sole, a popular local restaurant. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. Another top-rated restaurant to try is Al Mangiar Bene. As a dining spot that gains high praise from guests, it’s an ideal choice to enhance your time to Perugia tonight.

After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at Caffè Fortebraccio, a well-loved spot among locals and tourists. Or, head to Caffe Del Banco. This bar boasts a welcoming environment that is perfect for winding down. You could also continue your night at Dempsey's Perugia, another top-rated place in the area.

Say good night to Perugia and look forward to another great day of your road trip in Italy!

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Day 10

Day 10

  • Perugia - Departure day
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  • Arco dei Gigli
  • Etruscan Arch
  • More

Day 10 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Perugia before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

On your last day in Italy, take time to indulge in shopping at Perugia’s popular marketplace. Look for keepsakes or souvenirs to remind you of your trip.

Begin your adventure at Arco Dei Gigli. This is an intriguing arco you should not miss.

Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Perugia.

If you're in the mood for something new, try Elfo Pub Perugia, another premier location with a delectable menu.

You’ll then say farewell to Perugia. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!

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