10-Day Italy Self-Drive Road Trip With Itinerary from Pescara to Rome, Florence, Venice, and Bologna

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Escape the ordinary with this exciting 10-day road trip through Italy. Explore the diverse landscapes, lively cities, and beyond. Pack your bags, hit the road, and prepare for an unforgettable journey!

This perfectly planned road trip itinerary in Italy takes you through some of the best places to see in the country. You will spend 2 nights in Pescara, 2 nights in Rome, 2 nights in Florence, 2 nights in Venice, and 1 night in Bologna. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Pescara, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Trevi Fountain and Colosseum are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Pantheon, learn more about the unique Piazza Navona, and immerse yourself in the vibrant atmosphere of Piazza San Marco.

As you hit the open road and drive through Pescara, Rome, Florence, Siena, Venice, Bologna, Modena, and Santa Maria degli Angeli, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.

Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!

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Driver’s age is 30 - 65
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Itinerary summary

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Days
Destination
Attractions
Overnight
Day
City & Overnight
Attractions
Ponte del Mare
ColosseumRoman ForumTrevi FountainPiazza NavonaPantheon
Vatican MuseumsSistine ChapelSt Peter's BasilicaBorghese Gallery and MuseumTrastevere
Basilica of Santa Croce in FlorenceUffizi GalleryPonte VecchioPiazza della RepubblicaCathedral of Santa Maria del Fiorepiazza della Signoria
Tower of Mangiapiazza del CampoSiena CathedralFontebrandaBasilica of San DomenicoFortezza Medicea
Bridge of SighsDoge's PalaceSt Mark's BasilicaPiazza San MarcoRialto Bridge

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Day 1

Day 1

  • Pescara - Arrival day
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  • Ponte del Mare
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Say hello to Pescara! Your exciting road trip through Italy is just about to start. Navigating the top places to see in the region is a breeze with a car. The rental vehicle of your choice will be ready for pickup upon your arrival in the city. You will stay in Pescara for 1 night before you continue your adventure!

Pescara is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Ponte Del Mare, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Find your way to your hotel in Pescara. We recommend choosing a hotel in a central location for easy exploring. Check-in typically starts between 2 and 4 PM at hotels in Italy. Settle in and make plans for the evening.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Pescara, it's often a good idea to reserve a table in advance.

Dine in style at Taverna 58, a top recommendation for dinner tonight. Or, for a change of pace, Ristorante Carlo Ferraioli boasts a menu that's sure to impress. Also, be sure to check out Sesamo Nero. Known as a local hotspot, it’s a great choice for tonight in Pescara.

After your delicious meal, get a taste of the vibrant nightlife with a visit to Posa Caffè Pescara, known for its inviting atmosphere. Bar Mixer is another great option if you’re looking for a place to get the night started. Similarly, Temple Bar Irish Pub provides a great setting to enjoy the night away.

Raise a toast to the start of your 10-day road trip in Italy!

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Day 2

Day 2

  • Pescara
  • Rome
  • More

Drive 213 km, 3 hours 15 min

  • Colosseum
  • Roman Forum
  • Trevi Fountain
  • Piazza Navona
  • Pantheon
  • More

Dive into day 2 of your remarkable road trip in Italy. Today you will explore Rome, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Rome. You’ll stay here for 2 nights.

Get ready to discover some of the most iconic wonders in Pescara, including an archeological site, a monument, and a public square. Start your day at Colosseum. This historic archeological site is a timeless place to see in Pescara. Then, wander over to Roman Forum. If UNESCO world heritage-designated sites excite you, this archeological site will be right up your alley. Nearby, you’ll also find Trevi Fountain. This romantic monument is a favorite among visitors.

Pescara offers plenty to explore, ensuring every moment of your visit is filled with excitement and discovery. If you're up for more, Piazza Navona is a timeless spot in the city that will captivate you with its unique charm. When you’re done at the public square, don’t forget to check out the culturally significant Pantheon. Take a moment to appreciate the fascinating details of this timeless monument.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Rome. Rome offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As you explore more of Rome, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Savor the flavors at La Bottega Roma, a top pick for dinner tonight. Alternatively, Pasta In Corso beckons with its unique menu offerings. Also, consider Trattoria Vecchia Roma. With its consistent customer satisfaction, it’s an excellent option for dining in Rome tonight.

Continue the enjoyment post-dinner at La Botticella Of Poggi Giovanni, a cherished local gathering spot renowned for its welcoming atmosphere. Similarly, Almalu Trastevere offers a vibrant space for indulging in well-crafted drinks and engaging conversation. You may also want to check out Bar Viminale Di Pepi Maurilio. This bar is a favorite among both locals and visitors looking for a delightful evening out filled with laughter and fun.

Relax and recharge in preparation for another adventurous day in Italy!

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Day 3

Day 3

  • Rome
  • More

Drive 16 km, 1 hour

  • Vatican Museums
  • Sistine Chapel
  • St Peter's Basilica
  • Borghese Gallery and Museum
  • Trastevere
  • More

On day 3 of your road trip, you’ll start and end your day in Rome, where you'll stay for 1 night more.

At the top of the list of things to do today is to explore Trastevere, a neighborhood that captures the true essence of Vatican City. Take your time to uncover its best sides and enjoy its proximity to many of the area’s best attractions.

Continue your journey to St. Peter's Basilica, one of the city’s most globally renowned spots that you shouldn’t miss. Another great site to visit is the interesting Villa Borghese Pinciana.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Rome.

Indulge in a memorable dining experience at one of Rome's most popular restaurants, and connect with friendly locals for an authentic adventure.

Enjoy a delicious meal at RomAntica, a highly-rated dining destination in Rome. If you're eager to try something different, consider Coso Ristorante, another top spot with a tantalizing menu. You might also want to secure a reservation at DEROMA - Farine Romane. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Rome this evening.

If you’re not ready to end the night just yet, Sant' Eustachio Caffè offers a perfect venue to relax and savor a drink. Similarly, Yellowsquare Rome is well-suited for those looking to unwind in a social setting. Caffè Portofino is another excellent spot to enjoy a nightcap after a delightful meal.

Say good night to Rome and look forward to another great day of your road trip in Italy!

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Day 4

Day 4

  • Rome
  • Florence
  • More

Drive 276 km, 3 hours 31 min

  • Basilica of Santa Croce in Florence
  • Uffizi Gallery
  • Ponte Vecchio
  • Piazza della Repubblica
  • Cathedral of Santa Maria del Fiore
  • piazza della Signoria
  • More

Embark on another extraordinary experience on day 4 of your road trip in Italy. Today, you will make 1 stop and experience some of the highlights of Florence. At the end of the day, you will enjoy the comforts of a top-rated hotel in Florence, which will be your home away from home for 2 nights.

Whether you prefer a leisurely exploration or a more fast-paced adventure, this itinerary in Rome allows for both. Start by heading to Basilica Of Santa Croce In Florence. This well-known church provides an insightful glimpse into the city's identity. Next, discover Uffizi Gallery, a romantic art gallery, promising a delightful encounter.

Continue your sightseeing with a visit to Ponte Vecchio, a world-famous historical landmark. When you’re done, don’t forget to make a stop at the captivating Piazza Della Repubblica. Not far away from the public square, you will find the history-steeped Piazza Della Signoria, perfect for a quick visit. Round off your day at Cathedral Of Santa Maria Del Fiore, another gem in Rome with visually striking features to discover.

When you’re done exploring for the day, you’ll drive to your hotel in Florence. Check in and spend some time relaxing before you head out to tour the city.

Indulge in a memorable dining experience at one of Florence's most popular restaurants, and connect with friendly locals for an authentic adventure.

Make sure to reserve a table at Ristorante Oliviero 1962, an iconic dining spot in Florence. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Di Poneta Novoli, a popular restaurant in Florence. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Caffe San Firenze, a hidden gem nestled in Florence. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Round off your dining experience by visiting Manifattura, a prime location for a drink. Alternatively, explore the distinctive characteristics of Se·sto On Arno Rooftop Bar, a bar catering to every mood and preference. Il Vinile likewise offers a unique atmosphere, perfect for a memorable night out.

Take some time to reflect on your day and savor another beautiful night in Italy.

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Day 5

Day 5

  • Florence
  • More

Drive 156 km, 3 hours

  • Tower of Mangia
  • piazza del Campo
  • Siena Cathedral
  • Fontebranda
  • Basilica of San Domenico
  • Fortezza Medicea
  • More

At the end of the day, you'll drive back to Florence, where you'll stay for 1 night more.

Today’s itinerary in Florence covers several incredible sights, including a monument, a public square, a church, a historical landmark and much more! Start your adventure at Tower Of Mangia. This intriguing monument is a place that is appreciated by travelers and locals alike. Next, immerse yourself in the visually striking wonders of Piazza Del Campo, a must-see public square in the city.

Consider stopping for a small bite to eat or a drink at a local eatery to keep your energy going. When you’re ready, continue your discovery with a visit to Siena Cathedral. This popular church offers an enriching experience. For a change of pace, head to Fontebranda, where you can take in symbolic features. Conclude your self-guided sightseeing tour with a visit to Basilica Of San Domenico and Fortezza Medicea (siena). These sights offer a fulfilling end to a perfect day.

When you’re done exploring for the day, you’ll return to Florence and your accommodation.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Florence. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Savor the flavors at Ditta Artigianale, a top pick for dinner tonight. Alternatively, Trattoria Da Burde beckons with its unique menu offerings. Also, consider Casa Toscana. With its consistent customer satisfaction, it’s an excellent option for dining in Florence tonight.

Following your dinner, dive into the local bar culture at Bar 50 Rosso. Enjoy this evening's relaxed ambiance with delightful drinks. Alternatively, go to Bitter Bar, the perfect place for those looking to experience the best of the nightlife. Similarly, Archea Brewery provides excellent drinks and a great atmosphere, ensuring a memorable night out.

As the sun sets on another day of adventure, rest up and recharge for the next leg of your road trip in Italy.

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Day 6

Day 6

  • Florence
  • Venice
  • More

Drive 261 km, 3 hours 35 min

  • Bridge of Sighs
  • Doge's Palace
  • St Mark's Basilica
  • Piazza San Marco
  • Rialto Bridge
  • More

On day 6 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Venice. In the evening, you’ll end up in Venice, where you will stay for 2 nights.

Today, you'll explore some of the most beautiful places in Florence, including a monument, a palace, a church, a public square, a historical landmark and much more! Start your day with a visit to Bridge Of Sighs. This locally renowned monument is a must-visit in the city. When you’re ready for your next discovery, continue to Doge's Palace, which may be one of the most enchanting places you will experience today.

One of the best things about exploring Florence on a self-guided tour is that you set the pace. There’s plenty of time for detours and discovering hidden gems. When you’re ready for your next stop, make your way to St Mark's Basilica, a locally renowned church in the city. If you’re up for more discoveries, don’t forget to reserve some time for Piazza San Marco and Rialto Bridge.

At the end of the day, you will drive to Venice, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As dinnertime approaches, it's time to head out for a bite to eat in Venice. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Treat yourself to a delightful dinner at Bauer Hotel, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try L'Osteria Le Guglie? It's another excellent option with a diverse menu. Consider reserving a table at Corner Pub as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Venice.

If you’re not ready to end the night just yet, Al Parlamento offers a perfect venue to relax and savor a drink. Similarly, The Caffe Rosso is well-suited for those looking to unwind in a social setting. Adagio is another excellent spot to enjoy a nightcap after a delightful meal.

Say good night to Venice and look forward to another great day of your road trip in Italy!

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Day 7

Day 7

  • Venice
  • More

Drive 7 km, 1 hour 9 min

  • Basilica S.Maria Gloriosa dei Frari
  • Grand Canal
  • Palazzo Contarini del Bovolo
  • Teatro La Fenice
  • Peggy Guggenheim Collection
  • Santa Maria della Salute
  • More

Day 7 of your road trip across Italy promises a magnificent time exploring Venice. You have 1 night left in Venice. Take the opportunity to experience more of the best attractions and activities in the city.

Today, you'll explore some of the most beautiful places in Venice, including a church, a street, a palace, an opera house, an art gallery and much more! Start your day with a visit to Santa Maria Gloriosa Dei Frari. This locally appreciated church is a must-visit in the city. When you’re ready for your next discovery, continue to Grand Canal, which may be one of the most UNESCO world heritage-designated places you will experience today.

One of the best things about exploring Venice on a self-guided tour is that you set the pace. There’s plenty of time for detours and discovering hidden gems. When you’re ready for your next stop, make your way to Palazzo Contarini Del Bovolo, an interesting palace in the city. If you’re up for more discoveries, don’t forget to reserve some time for Teatro La Fenice and Peggy Guggenheim Collection. End your day with a visit to Santa Maria Della Salute, a curiosity-inducing church that’s sure to leave a lasting impression.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

As dinnertime approaches, it's time to head out for a bite to eat in Venice. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Treat yourself to a delicious dinner at Generator Venice, an excellent option for tonight's dining. Looking for something different? Nevodi offers a tantalizing alternative with its diverse menu. And don’t miss Ristorante La Piazza. With its reputation for pleasing customers, it’s a fantastic choice for tonight in Venice.

After enjoying a fulfilling meal, continue your evening at Il Mercante, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, The Irish Pub Venezia offers a welcoming atmosphere for easing into the nightlife. Similarly, Ai Stagneri provides an excellent environment for a relaxed and enjoyable evening.

As the sun sets on another day of adventure, rest up and recharge for the next leg of your road trip in Italy.

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Day 8

Day 8

  • Venice
  • Bologna
  • More

Drive 154 km, 2 hours 11 min

  • Pinacoteca Nazionale di Bologna
  • Piazza Santo Stefano
  • Two Towers
  • Bologna Cathedral
  • Fountain of Neptune, Bologna
  • Piazza Maggiore
  • More

Experience an unparalleled adventure on day 8 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 vibrant destinations - Bologna. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Bologna. You will spend 1 night here for some well-deserved relaxation.

Get ready for a day filled with family-friendly attractions, photo-friendly spots, and historic treasures in the charming city of Venice. Your adventure starts at Pinacoteca Nazionale Di Bologna, an increasingly popular local hot spot. Another notable attraction to explore is Piazza Santo Stefano. This increasingly popular public square is known for its history-steeped appeal.

After soaking in the highlights of these sights, take some time to wander Venice's streets and immerse yourself in the local atmosphere. When you're ready to continue your sightseeing adventure, head to Two Towers. This culturally significant monument offers a fascinating experience that many visitors find memorable. Bologna Cathedral is also worth visiting, along with Fountain Of Neptune, Bologna. These standout landmarks offer unique experiences that add to the day’s enjoyment. End your day at Piazza Maggiore. This spectacular public square provides a fitting finale to your sightseeing.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Bologna. Bologna offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a day of adventure, treat yourself to an exquisite dinner at one of Bologna's best restaurants.

Enjoy a delicious meal at Ristorante Ciacco, a top-rated dining destination in Bologna. If you're in the mood to try something new, consider Ristorante Ballarini, another top spot with a mouthwatering menu. You might also want to secure a reservation at Sfoglia Rina. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Bologna this evening.

Keep the evening going at Bar Al Bricco D'oro, a great choice for enjoying the after-dinner hours with a drink. You could also go to Bar Freud E Squisito, which offers a similarly pleasant setting and great drinks. Another option is Osteria Del Sole, which provides an inviting environment for unwinding after a busy day out.

Head back to your accommodation in Bologna and get some rest in preparation for another magical day of your road trip in Italy!

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Day 9

Day 9

  • Bologna
  • Pescara
  • More

Drive 572 km, 6 hours 47 min

  • Museo Stanguellini
  • Basilica of San Francesco d'Assisi
  • Chiesa di San Pietro
  • More

On day 9 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 3 destinations, Modena, Santa Maria degli Angeli, and Valecchie. When you’re not sightseeing, take time to relax at your selected hotel in Pescara, where you’ll be staying for 1 night.

Bring your curiosity for today’s adventure around Bologna. Some of the city’s most loved attractions await! Museo Stanguellini is the perfect place to start. This museum is one of the most often recommended places to visit in Bologna. Next, head to Basilica Of San Francesco D'assisi, a well-known church, known for its breathtaking features.

In between the sights, don’t hesitate to take small detours to explore local stores and eateries. When you’re ready to continue your adventure, head to Chiesa Di San Pietro. This respected church is a highly recommended experience. Visit these for an interesting touch to your journey.

When you’re done exploring for the day, you’ll drive to your hotel in Pescara. Check in and spend some time relaxing before you head out to tour the city.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Pescara. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Enjoy a delicious meal at Ciacco, a highly-rated dining destination in Pescara. If you're eager to try something different, consider Bar Sara, another top spot with a tantalizing menu. You might also want to secure a reservation at Ristorante Franco. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Pescara this evening.

After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at Bar Napoli, a well-loved spot among locals and tourists. Or, head to Bar Supermarket. This bar boasts a welcoming environment that is perfect for winding down. You could also continue your night at Post Bar, another top-rated place in the area.

Celebrate another amazing day of your road trip adventure in Italy!

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Day 10

Day 10

  • Pescara - Departure day
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  • Nature Reserve Pineta Dannunziana
  • More

Day 10 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Pescara before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, we recommend visiting Nature Reserve Pineta Dannunziana, a mesmerizing nature reserve before you head out.

As your final day in Italy unfolds, enjoy a last-minute shopping spree in Pescara's best shopping area, Centro Commerciale Pescara Porta Nuova. Enjoy finding the perfect gift or keepsake to remind you of your wonderful trip to Italy.

Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Pescara.

Savor the flavors at MuuLab. Cucina e Distillati, a top pick for dinner tonight. Alternatively, La Taverna Antica beckons with its unique menu offerings.

You’ll then say farewell to Pescara. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!

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