10-Day Italy Self-Drive Road Trip With Itinerary from Pescara to Rome, Florence, Venice, and Bologna

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Experience the freedom of the open road in Italy as you embark on an unforgettable 10-day road trip! This experience caters to every traveler, featuring destinations like Pescara, Rome, Florence, Siena, Venice, Bologna, Modena, and Santa Maria degli Angeli.

This perfectly planned road trip itinerary in Italy takes you through some of the best places to see in the country. You will spend 2 nights in Pescara, 2 nights in Rome, 2 nights in Florence, 2 nights in Venice, and 1 night in Bologna. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Pescara, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Trevi Fountain and Colosseum are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Pantheon, learn more about the unique Piazza Navona, and immerse yourself in the vibrant atmosphere of Piazza San Marco.

As you hit the open road and drive through Pescara, Rome, Florence, Siena, Venice, Bologna, Modena, and Santa Maria degli Angeli, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.

Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!

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Itinerary summary

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Days
Destination
Attractions
Overnight
Day
City & Overnight
Attractions
Ponte del Mare
ColosseumRoman ForumTrevi FountainPiazza NavonaPantheon
Vatican MuseumsSistine ChapelSt Peter's BasilicaBorghese Gallery and MuseumTrastevere
Basilica of Santa Croce in FlorenceUffizi GalleryPonte VecchioPiazza della RepubblicaCathedral of Santa Maria del Fiorepiazza della Signoria
Tower of Mangiapiazza del CampoSiena CathedralFontebrandaBasilica of San DomenicoFortezza Medicea
Bridge of SighsDoge's PalaceSt Mark's BasilicaPiazza San MarcoRialto Bridge

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Day 1

Day 1

  • Pescara - Arrival day
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  • Ponte del Mare
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Your road trip adventure in Italy begins as soon as you reach Pescara and pick up your car. You’ll stay in Pescara for 1 night and explore the best things to see and do, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.

Pescara is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Ponte Del Mare, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Find your way to your hotel in Pescara. We recommend choosing a hotel in a central location for easy exploring. Check-in typically starts between 2 and 4 PM at hotels in Italy. Settle in and make plans for the evening.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Pescara, it's often a good idea to reserve a table in advance.

Have a fantastic dining experience at Taverna 58, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Ristorante Carlo Ferraioli offers an enticing alternative with its varied menu. Additionally, Sesamo Nero is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Pescara.

To truly maximize your evening out, consider visiting Posa Caffè Pescara after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to Bar Mixer, another bar with an inviting ambiance. Similarly, Temple Bar Irish Pub also offers a great atmosphere, ensuring a night filled with enjoyment and relaxation.

Raise a toast to the start of your 10-day road trip in Italy!

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Day 2

Day 2

  • Pescara
  • Rome
  • More

Drive 213 km, 3 hours 15 min

  • Colosseum
  • Roman Forum
  • Trevi Fountain
  • Piazza Navona
  • Pantheon
  • More

On day 2 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, Rome. When you’re not sightseeing, take time to relax at your selected hotel in Rome, where you’ll be staying for 2 nights.

Discover a day packed with family-friendly attractions, scenic views, and photo-friendly spots in Pescara. Begin your sightseeing with Colosseum. This world-famous archeological site is one of the top attractions in the city. Proceed to Roman Forum, another must-visit attraction.

As you wander through the inviting streets of Pescara, soak in the lively ambiance and take the opportunity to snap some photos. Next, head to Trevi Fountain. This iconic monument is a traveler-favorite. Not far away, you’ll find Piazza Navona, another key site on your sightseeing itinerary. Pantheon is yet another highly recommended place to visit nearby, offering plenty to discover for curious travelers.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Rome. Rome offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As dinnertime approaches, it's time to head out for a bite to eat in Rome. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Have a fantastic dining experience at La Bottega Roma, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Pasta In Corso offers an enticing alternative with its varied menu. Additionally, Trattoria Vecchia Roma is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Rome.

After enjoying a fulfilling meal, continue your evening at La Botticella Of Poggi Giovanni, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, Almalu Trastevere offers a welcoming atmosphere for easing into the nightlife. Similarly, Bar Viminale Di Pepi Maurilio provides an excellent environment for a relaxed and enjoyable evening.

Get a good night's sleep and look forward to another great day on the road in Italy!

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Day 3

Day 3

  • Rome
  • More

Drive 16 km, 1 hour

  • Vatican Museums
  • Sistine Chapel
  • St Peter's Basilica
  • Borghese Gallery and Museum
  • Trastevere
  • More

On day 3 of your road trip in Italy, you’ll start and end your day in Rome, but spend the day exploring what’s beyond the city. Since you will return to Rome for 1 night more, there’s no need to rush. Experience Vatican City and Rome to the fullest today with this curated day itinerary!

Trastevere is one of the highlights of today. Take your time exploring this iconic neighborhood in Vatican City, which offers a perfect blend of history and culture. Plus, it's close to many must-see landmarks in the city.

Today’s well-planned self-sightseeing route offers several fun adventures, romantic experiences, and scenic views. Whether you decide to explore Rome on foot, use public transport, or join a guided tour, there are a few attractions you don’t want to miss. Vatican Museums is the first of them. Sistine Chapel is your next stop. This astonishing chapel is one of the best-rated sights in Rome.

Consider grabbing some lunch or a light snack to keep your energy going. Beyond the above-mentioned attractions, today is also the perfect time to visit St. Peter's Basilica. To round off your sightseeing experience, visit Villa Borghese Pinciana.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Rome.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Rome. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Dine in style at RomAntica, a top recommendation for dinner tonight. Or, for a change of pace, Coso Ristorante boasts a menu that's sure to impress. Also, be sure to check out DEROMA - Farine Romane. Known as a local hotspot, it’s a great choice for tonight in Rome.

Keep the excitement of the evening going by visiting a bar or two. Sant' Eustachio Caffè is an excellent place to start. You could also check out Yellowsquare Rome, offering a different kind of charm. A last recommendation for the day is Caffè Portofino. This bar promises an enjoyable experience with tasty drinks and a vibrant setting.

Raise your glass to another unforgettable day in Italy!

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Day 4

Day 4

  • Rome
  • Florence
  • More

Drive 276 km, 3 hours 31 min

  • Basilica of Santa Croce in Florence
  • Uffizi Gallery
  • Ponte Vecchio
  • Piazza della Repubblica
  • Cathedral of Santa Maria del Fiore
  • piazza della Signoria
  • More

On day 4 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Florence. In the evening, you’ll end up in Florence, where you will stay for 2 nights.

Get ready for a day filled with fun adventures, picturesque spots, and historic treasures in the charming city of Rome. Your adventure starts at Basilica Of Santa Croce In Florence, an interesting local hot spot. Another notable attraction to explore is Uffizi Gallery. This extraordinary art gallery is known for its respected appeal.

After soaking in the highlights of these sights, take some time to wander Rome's streets and immerse yourself in the local atmosphere. When you're ready to continue your sightseeing adventure, head to Ponte Vecchio. This culturally significant historical landmark offers a fascinating experience that many visitors find memorable. Piazza Della Repubblica is also worth visiting, along with Cathedral Of Santa Maria Del Fiore. These standout landmarks offer unique experiences that add to the day’s enjoyment. End your day at Piazza Della Signoria. This spectacular public square provides a fitting finale to your sightseeing.

At the end of the day, you will drive to Florence, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you explore more of Florence, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Treat yourself to a delightful dinner at Ristorante Oliviero 1962, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Di Poneta Novoli? It's another excellent option with a diverse menu. Consider reserving a table at Caffe San Firenze as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Florence.

After your delicious meal, get a taste of the vibrant nightlife with a visit to Manifattura, known for its inviting atmosphere. Se·sto On Arno Rooftop Bar is another great option if you’re looking for a place to get the night started. Similarly, Il Vinile provides a great setting to enjoy the night away.

Raise your glass to another unforgettable day in Italy!

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Day 5

Day 5

  • Florence
  • More

Drive 156 km, 3 hours

  • Tower of Mangia
  • piazza del Campo
  • Siena Cathedral
  • Fontebranda
  • Basilica of San Domenico
  • Fortezza Medicea
  • More

On day 5 of your road trip, you’ll start and end your day in Florence, where you'll stay for 1 night more.

Whether you prefer a leisurely exploration or a more fast-paced adventure, this itinerary in Florence allows for both. Start by heading to Tower Of Mangia. This frequently visited monument provides an insightful glimpse into the city's identity. Next, discover Piazza Del Campo, a history-steeped public square, promising a delightful encounter.

Continue your sightseeing with a visit to Siena Cathedral, a locally renowned church. When you’re done, don’t forget to make a stop at the often recommended Fontebranda. Not far away from the historical landmark, you will find the awe-inspiring Fortezza Medicea (siena), perfect for a quick visit. Round off your day at Basilica Of San Domenico, another gem in Florence with majestic features to discover.

When you’re done exploring for the day, you’ll return to Florence and your accommodation.

Indulge in a memorable dining experience at one of Florence's most popular restaurants, and connect with friendly locals for an authentic adventure.

Have a fantastic dining experience at Ditta Artigianale, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Trattoria Da Burde offers an enticing alternative with its varied menu. Additionally, Casa Toscana is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Florence.

Explore the vibrant nightlife at Bar 50 Rosso after your meal, a hub for lively evenings and memorable moments. Or, head to Bitter Bar for a great selection of flavorful drinks and a charming setting. Furthermore, Archea Brewery is perfect for those looking to extend their night with a touch of local flavor.

Savor another day of unforgettable experiences in Italy!

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Day 6

Day 6

  • Florence
  • Venice
  • More

Drive 261 km, 3 hours 35 min

  • Bridge of Sighs
  • Doge's Palace
  • St Mark's Basilica
  • Piazza San Marco
  • Rialto Bridge
  • More

Embark on another extraordinary experience on day 6 of your road trip in Italy. Today, you will make 1 stop and experience some of the highlights of Venice. At the end of the day, you will enjoy the comforts of a top-rated hotel in Venice, which will be your home away from home for 2 nights.

Today, you'll explore some of the most beautiful places in Florence, including a monument, a palace, a church, a public square, a historical landmark and much more! Start your day with a visit to Bridge Of Sighs. This interesting monument is a must-visit in the city. When you’re ready for your next discovery, continue to Doge's Palace, which may be one of the most enchanting places you will experience today.

One of the best things about exploring Florence on a self-guided tour is that you set the pace. There’s plenty of time for detours and discovering hidden gems. When you’re ready for your next stop, make your way to St Mark's Basilica, a notable church in the city. If you’re up for more discoveries, don’t forget to reserve some time for Piazza San Marco and Rialto Bridge.

When you’re done exploring for the day, you’ll drive to your hotel in Venice. Check in and spend some time relaxing before you head out to tour the city.

After a day of adventure, treat yourself to an exquisite dinner at one of Venice's best restaurants.

Enjoy a lovely meal at Bauer Hotel, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, L'Osteria Le Guglie is another top choice with a popular menu. You could also check for a table at Corner Pub. As an establishment that gains consistently high praises from customers, it’s an ideal choice in Venice tonight.

Explore the vibrant nightlife at Al Parlamento after your meal, a hub for lively evenings and memorable moments. Or, head to The Caffe Rosso for a great selection of flavorful drinks and a charming setting. Furthermore, Adagio is perfect for those looking to extend their night with a touch of local flavor.

Relax and reminisce about your day in Italy and look forward to more memorable moments to come!

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Day 7

Day 7

  • Venice
  • More

Drive 7 km, 1 hour 9 min

  • Basilica S.Maria Gloriosa dei Frari
  • Grand Canal
  • Palazzo Contarini del Bovolo
  • Teatro La Fenice
  • Peggy Guggenheim Collection
  • Santa Maria della Salute
  • More

On day 7 of your road trip, you will have an entire day to explore Venice. You’ll stay in Venice for 1 night and discover all the best things to see and do in the area.

Today’s agenda in Venice includes a church, a street, a palace, an opera house, an art gallery and much more! Santa Maria Gloriosa Dei Frari is must-visit church and a great starting point for the day. Next, continue your journey to Grand Canal, a beloved street, located just a leisurely stroll away. Next, head to Palazzo Contarini Del Bovolo, a romantic palace, also available for your discovery today.

Each stop on today’s itinerary promises to leave you with lasting memories and a deeper appreciation for Venice. When you're ready, let your sightseeing route take you to the popular Teatro La Fenice. If you’re looking for more, Peggy Guggenheim Collection is also a popular attraction that is worthwhile a visit. Lastly, don’t miss Santa Maria Della Salute, a place of enchanting interest in the city.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

After a day of adventure, treat yourself to an exquisite dinner at one of Venice's best restaurants.

Dine in style at Generator Venice, a top recommendation for dinner tonight. Or, for a change of pace, Nevodi boasts a menu that's sure to impress. Also, be sure to check out Ristorante La Piazza. Known as a local hotspot, it’s a great choice for tonight in Venice.

Keep the evening going at Il Mercante, a great choice for enjoying the after-dinner hours with a drink. You could also go to The Irish Pub Venezia, which offers a similarly pleasant setting and great drinks. Another option is Ai Stagneri, which provides an inviting environment for unwinding after a busy day out.

As the sun sets on another day of adventure, rest up and recharge for the next leg of your road trip in Italy.

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Day 8

Day 8

  • Venice
  • Bologna
  • More

Drive 154 km, 2 hours 11 min

  • Pinacoteca Nazionale di Bologna
  • Piazza Santo Stefano
  • Two Towers
  • Bologna Cathedral
  • Fountain of Neptune, Bologna
  • Piazza Maggiore
  • More

Experience an unparalleled adventure on day 8 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 vibrant destinations - Bologna. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Bologna. You will spend 1 night here for some well-deserved relaxation.

Get ready for an exciting day in Venice. Today’s sightseeing agenda includes an art gallery, a public square, a monument, a church and much more! Begin your adventure at Pinacoteca Nazionale Di Bologna. This is a curiosity-inducing art gallery you should not miss. Another must-see is Piazza Santo Stefano, a frequently visited public square in Venice.

When you’re ready for the next sight, head to Two Towers. From there, take a leisurely stroll to Bologna Cathedral, another of the city’s underrated attractions. We recommend continuing your self-guided tour at Fountain Of Neptune, Bologna, a photogenic place of interest in the city. If time allows, add Piazza Maggiore to your itinerary. This extraordinary public square offers the perfect finishing touch to your day in Venice.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Bologna. Bologna offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Bologna. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Dine in style at Ristorante Ciacco, a top recommendation for dinner tonight. Or, for a change of pace, Ristorante Ballarini boasts a menu that's sure to impress. Also, be sure to check out Sfoglia Rina. Known as a local hotspot, it’s a great choice for tonight in Bologna.

To truly maximize your evening out, consider visiting Bar Al Bricco D'oro after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to Bar Freud E Squisito, another bar with an inviting ambiance. Similarly, Osteria Del Sole also offers a great atmosphere, ensuring a night filled with enjoyment and relaxation.

Head back to your accommodation in Bologna and get some rest in preparation for another magical day of your road trip in Italy!

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Day 9

Day 9

  • Bologna
  • Pescara
  • More

Drive 572 km, 6 hours 47 min

  • Museo Stanguellini
  • Basilica of San Francesco d'Assisi
  • Chiesa di San Pietro
  • More

Dive into day 9 of your remarkable road trip in Italy. Today you will explore Modena, Santa Maria degli Angeli, and Valecchie, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Pescara. You’ll stay here for 1 night.

A blend of family-friendly attractions, picturesque spots, and history-rich sites await you in Bologna on today’s itinerary. First up is the often recommended museum, Museo Stanguellini. Afterward, continue to Basilica Of San Francesco D'assisi, a church every traveler should visit.

As you explore Bologna’s charming streets, take in the lively atmosphere and get to know the character of the city. Next, make your way to Chiesa Di San Pietro. This beloved church is an essential stop.

At the end of the day, you will drive to Pescara, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

Indulge in a memorable dining experience at one of Pescara's most popular restaurants, and connect with friendly locals for an authentic adventure.

Enjoy a delicious meal at Ciacco, a top-rated dining destination in Pescara. If you're in the mood to try something new, consider Bar Sara, another top spot with a mouthwatering menu. You might also want to secure a reservation at Ristorante Franco. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Pescara this evening.

After savoring a delicious meal, step into the vibrant nightlife at Bar Napoli, where the evening is just getting started. In the same way, Bar Supermarket offers a unique charm perfect for experiencing the local bar scene in Pescara. Post Bar is another top-recommended bar that is sure to get you into the mood for some dancing and celebrating.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in Italy.

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Day 10

Day 10

  • Pescara - Departure day
  • More
  • Nature Reserve Pineta Dannunziana
  • More

Day 10 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Pescara before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, begin at Nature Reserve Pineta Dannunziana. This underrated nature reserve is a popular place to see in the city.

Make the most of your final day in Italy by visiting Pescara’s iconic markets and shopping establishments in the buzzing Centro Commerciale Pescara Porta Nuova. Secure the perfect souvenirs for your family and friends back home or buy yourself a remembrance of your amazing experience in Italy.

Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Pescara.

Have a fantastic dining experience at MuuLab. Cucina e Distillati, a highly recommended choice for tonight's dinner. If you're looking to mix things up, La Taverna Antica offers an enticing alternative with its varied menu.

You’ll then say farewell to Pescara. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!

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