10-Day Italy Self-Drive Road Trip With Itinerary from Pescara to Rome, Florence, Venice, and Bologna

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Spectacular summer view from flying drone Pescara port. Attractive sunset on Adriatic sea. Breathtaking evening scene of Italy, Europe.
View of the Pescara city hall and surrounding buildings, Pescara, Italy.
10-Day Italy Self-Drive Road Trip With Itinerary from Pescara to Rome, Florence, Venice, and Bologna
10-Day Italy Self-Drive Road Trip With Itinerary from Pescara to Rome, Florence, Venice, and Bologna
10-Day Italy Self-Drive Road Trip With Itinerary from Pescara to Rome, Florence, Venice, and Bologna
10-Day Italy Self-Drive Road Trip With Itinerary from Pescara to Rome, Florence, Venice, and Bologna
10-Day Italy Self-Drive Road Trip With Itinerary from Pescara to Rome, Florence, Venice, and Bologna
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Escape the ordinary with this exciting 10-day road trip through Italy. Explore diverse landscapes, discover lively cities, and prepare for an unforgettable journey!

This perfectly planned road trip itinerary takes you through some of the best places to see in Italy. You will spend 2 nights in Pescara, 2 nights in Rome, 2 nights in Florence, 2 nights in Venice, and 1 night in Bologna. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Pescara, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Trevi Fountain and Colosseum are just a couple of the bucket-list attractions that await your discovery.

As you hit the open road and drive through Pescara, Rome, Florence, Siena, Venice, Bologna, Modena, and Santa Maria degli Angeli, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.

Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!

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Driver’s age is 30 - 65
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Day1

Day 1

  • Pescara - Arrival day
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  • Ponte del Mare
  • More

Say hello to Pescara! Your exciting road trip through Italy is just about to start. Navigating the top places to see in the region is a breeze with a car. The rental vehicle of your choice will be ready for pickup upon your arrival in the city. You will stay in Pescara for 1 night before you continue your adventure!

Pescara is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Ponte Del Mare. Taking a stroll in the city center is a great alternative. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

As afternoon approaches, head to your chosen hotel in Pescara. Check-in typically starts around 2 to 4 PM at hotels in Italy. We recommend staying at a central location for easy access to key areas in the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Pescara, it's often a good idea to reserve a table in advance.

Have a fantastic dining experience at Taverna 58, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Ristorante Carlo Ferraioli offers an enticing alternative with its varied menu. Additionally, Sesamo Nero is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Pescara.

After your meal, keep the night alive at a bar like Posa Caffè Pescara, known for its lively atmosphere. Bar Mixer is another top recommendation that provides the perfect setting with well-crafted drinks and a welcoming ambiance. Similarly, Temple Bar Irish Pub offers an excellent atmosphere for those looking to amp up the evening.

Raise a toast to the start of your 10-day road trip in Italy!

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Day2

Day 2

  • Pescara
  • Rome
  • More

Drive 213 km, 3 hours 15 min

  • Colosseum
  • Roman Forum
  • Trevi Fountain
  • Piazza Navona
  • Pantheon
  • More

Dive into day 2 of your remarkable road trip in Italy. Today you'll explore 1 destination, including Rome. At the end of the day, you’ll unwind at one of the finest accommodations in Rome, where you'll spend 2 nights.

It’s time to gear up for the next part of your road trip adventure. Under favorable conditions, your drive to Rome may take around 2 hours 19 min. Upon your arrival in Rome, you’ll be greeted with the opportunity to do some sightseeing and exploring.

For a more meaningful self-guided tour of the city's best attractions, visit Colosseum, an iconic archeological site that is sure to impress. Take in the surroundings and enjoy the freedom of exploring at your own pace before you continue your journey. Next, head to Roman Forum and admire its historic features.

When you’re ready, continue to Trevi Fountain, a timeless monument beloved by locals and tourists alike. Don't miss out on Piazza Navona, another highlight of the area that promises a memorable visit. Not far away, you’ll also find Pantheon, a culturally significant place to see that you won’t regret spending some extra time discovering.

At the end of the day, you will drive to Rome, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

Rome is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Rome.

Treat yourself to a delightful dinner at La Bottega Roma, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Pasta In Corso? It's another excellent option with a diverse menu. Consider reserving a table at Trattoria Vecchia Roma as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Rome.

Explore the vibrant nightlife at La Botticella Of Poggi Giovanni after your meal, a hub for lively evenings and memorable moments. Or, head to Almalu Trastevere for a great selection of flavorful drinks and a charming setting. Furthermore, Bar Viminale Di Pepi Maurilio is perfect for those looking to extend their night with a touch of local flavor.

Relax and recharge in preparation for another adventurous day in Italy!

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Day3

Day 3

  • Rome
  • Vatican City
  • More

Drive 16 km, 1 hour

  • Vatican Museums
  • Sistine Chapel
  • St Peter's Basilica
  • Borghese Gallery and Museum
  • Trastevere
  • More

On day 3 of your road trip, you’ll start and end your day in Rome, where you have 1 night left to stay.

Trastevere is a fantastic place you can explore today in Vatican City. This neighborhood is a testament to the city’s character, and it's easy to spend hours just walking around and admiring the surroundings. Soak in the Vatican City-way-of-life and visit all the nearby sights.

Check out the interesting museum, Villa Borghese Pinciana. As you explore Rome’s charming streets, take in the lively atmosphere and get to know the character of the city.

Admire the views and listen to some good music as you drive in the direction of Vatican City.

Next, continue your sightseeing at Sistine Chapel, an extraordinary chapel.

When you’re done exploring for the day, you’ll return to Rome and your accommodation.

Rome is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Rome.

Enjoy a delicious meal at RomAntica, a top-rated dining destination in Rome. If you're in the mood to try something new, consider Coso Ristorante, another top spot with a mouthwatering menu. You might also want to secure a reservation at DEROMA - Farine Romane. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Rome this evening.

Round off your dining experience by visiting Sant' Eustachio Caffè, a prime location for a drink. Alternatively, explore the distinctive characteristics of Yellowsquare Rome, a bar catering to every mood and preference. Caffè Portofino likewise offers a unique atmosphere, perfect for a memorable night out.

Take some time to reflect on your day and savor another beautiful night in Italy.

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Day4

Day 4

  • Rome
  • Florence
  • More

Drive 276 km, 3 hours 31 min

  • Basilica of Santa Croce in Florence
  • Uffizi Gallery
  • Ponte Vecchio
  • Piazza della Repubblica
  • Cathedral of Santa Maria del Fiore
  • piazza della Signoria
  • More

On day 4 of your road trip in Italy, your travel plans include 1 stop at the most scenic, wondrous, and interesting places in the region. Florence are on today's agenda. In the evening, you’ll end up in Florence, where you will stay for 2 nights.

Once you're ready to continue your road trip, it's time to buckle up and drive, eagerly anticipating your arrival in Florence. This drive usually takes around 3 hours 2 min, without any stops or traffic disruptions.

Set out on a self-guided sightseeing tour at Basilica Of Santa Croce In Florence and explore the respected features. Next, make your way to Uffizi Gallery, another highlight in Florence. When you’re done exploring the art gallery, continue to Ponte Vecchio, a history-steeped historical landmark.

Nearby, you will also find Piazza Della Repubblica. This locally renowned public square is a top place to see in the area. Lastly, head to Cathedral Of Santa Maria Del Fiore, a history-steeped church that is perfect for some final exploring in the city.

When you’re done exploring for the day, you’ll drive to your hotel in Florence. Check in and relax before you head out to tour the city.

Indulge in a memorable dining experience at one of Florence's most popular restaurants, and connect with friendly locals for a true cultural experience.

Enjoy a delicious meal at Ristorante Oliviero 1962, a highly-rated dining destination in Florence. If you're eager to try something different, consider Di Poneta Novoli, another top spot with a tantalizing menu. You might also want to secure a reservation at Caffe San Firenze. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Florence this evening.

Following your dinner, dive into the local bar culture at Manifattura. Enjoy this evening's relaxed ambiance with delightful drinks. Alternatively, go to Se·sto On Arno Rooftop Bar, the perfect place for those looking to experience the best of the nightlife. Similarly, Il Vinile provides excellent drinks and a great atmosphere, ensuring a memorable night out.

Get a good night's sleep and look forward to another great day on the road in Italy!

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Day5

Day 5

  • Florence
  • Siena
  • More

Drive 156 km, 3 hours

  • Tower of Mangia
  • piazza del Campo
  • Siena Cathedral
  • Fontebranda
  • Basilica of San Domenico
  • Fortezza Medicea
  • More

Greet day 5 of your road trip in Italy with a smile and start your day with a hearty breakfast. You have 1 night to stay in Florence, so get ready to make the most of your time in the region. On the agenda for this day, you’ll find only the best things to see and do in Siena.

After soaking in Florence’s unique atmosphere, jump into the car with a full heart and drive in the direction of your next destination: Siena. Expect your car journey to take a minimum of 1 hour 15 min. When you arrive in Siena, it's time to take a break from the road.

For a more meaningful self-guided tour of the city's best attractions, visit Tower Of Mangia, an often recommended monument that is sure to impress. Take in the surroundings and enjoy the freedom of exploring at your own pace before you continue your journey. Next, head to Piazza Del Campo and admire its enchanting features.

When you’re ready, continue to Siena Cathedral, a captivating church beloved by locals and tourists alike. Don't miss out on Fontebranda, another highlight of the area that promises a memorable visit. Not far away, you’ll also find Basilica Of San Domenico, a majestic place to see that you won’t regret spending some extra time discovering.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Florence.

After a day of adventure, treat yourself to an exquisite dinner at one of Florence's best restaurants.

Treat yourself to a delightful dinner at Ditta Artigianale, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Trattoria Da Burde? It's another excellent option with a diverse menu. Consider reserving a table at Casa Toscana as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Florence.

After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at Bar 50 Rosso, a well-loved spot among locals and tourists. Or, head to Bitter Bar. This bar boasts a welcoming environment that is perfect for winding down. You could also continue your night at Archea Brewery, another top-rated place in the area.

Head back to your accommodation in Florence and get some rest to prepare for another magical day of your road trip in Italy.

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Day6

Day 6

  • Florence
  • Venice
  • More

Drive 261 km, 3 hours 35 min

  • Bridge of Sighs
  • Doge's Palace
  • St Mark's Basilica
  • Piazza San Marco
  • Rialto Bridge
  • More

On day 6 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, including Venice. When you’re not sightseeing, take time to relax at your chosen hotel in Venice, where you’ll be staying for 2 nights.

When you’ve had your share of Florence, prepare for your next destination. Admire the views and listen to some good music as you drive in the direction of Venice. Your travel time is around 2 hours 50 min.

Enjoy sightseeing at your own pace and allow yourself time to explore the beautiful surroundings. Take your self-guided tour to Bridge Of Sighs, a locally renowned monument that everyone visiting Venice should see. Next, head to Doge's Palace. This UNESCO world heritage-listed palace is one of the most interesting attractions in the region.

If you're keen to see more, don’t miss out on St Mark's Basilica, a history-steeped church popular among locals as well as travelers. Piazza San Marco is an excellent attraction to visit next. Spend some time learning more about this timeless public square before you continue your journey. Lastly, visit Rialto Bridge, a history-steeped historical landmark and a top attraction in the city.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Venice. Venice offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Venice, it's often a good idea to reserve a table in advance.

Enjoy a lovely meal at Bauer Hotel, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, L'Osteria Le Guglie is another top choice with a popular menu. You could also check for a table at Corner Pub. As an establishment that consistently gains high praises from customers, it’s an ideal choice in Venice tonight.

After savoring a delicious meal, step into the vibrant nightlife at Al Parlamento, where the evening is just getting started. In the same way, The Caffe Rosso offers a unique charm perfect for experiencing the local bar scene in Venice. Adagio is another top-recommended bar that is sure to get you into the mood for some dancing and celebrating.

Celebrate another amazing day of your road trip adventure in Italy!

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Day7

Day 7

  • Venice
  • More

Drive 7 km, 1 hour 9 min

  • Basilica S.Maria Gloriosa dei Frari
  • Grand Canal
  • Palazzo Contarini del Bovolo
  • Teatro La Fenice
  • Peggy Guggenheim Collection
  • Santa Maria della Salute
  • More

Day 7 offers an itinerary packed with the best things to see in Pescara. You’ll stay in Venice for 1 night more, offering you enough time to explore at a relaxed pace.

No visit to Venice is complete without Santa Maria Gloriosa Dei Frari. This worthwhile church is one of the top attractions in the city. Proceed to Grand Canal, another must-visit attraction.

As you wander through the inviting streets of Venice, soak in the lively ambiance and take the opportunity to snap some photos. Next, head to Palazzo Contarini Del Bovolo. This notable palace is a traveler-favorite. Not far away, you’ll find Teatro La Fenice, another key site on your sightseeing itinerary. Peggy Guggenheim Collection is yet another highly recommended place to visit nearby, offering plenty to discover for curious travelers. Conclude your day at Santa Maria Della Salute and uncover why it's recognized as one of the city's most often recommended attractions.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Venice. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Enjoy a delicious meal at Generator Venice, a top-rated dining destination in Venice. If you're in the mood to try something new, consider Nevodi, another top spot with a mouthwatering menu. You might also want to secure a reservation at Ristorante La Piazza. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Venice this evening.

Extend your evening after a delightful meal by visiting Il Mercante, which offers the perfect atmosphere for a night out. Moreover, The Irish Pub Venezia is another popular option for a drink or two. Likewise, Ai Stagneri also provides a great ambiance for reminiscing about the day and raising a toast to your vacation.

Relax and recharge in preparation for another adventurous day in Italy!

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Day8

Day 8

  • Venice
  • Bologna
  • More

Drive 154 km, 2 hours 11 min

  • Pinacoteca Nazionale di Bologna
  • Piazza Santo Stefano
  • Two Towers
  • Bologna Cathedral
  • Fountain of Neptune, Bologna
  • Piazza Maggiore
  • More

Experience an unparalleled adventure on day 8 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 place, which are Bologna. At the end of the day, you will retreat to the hotel of your choice in Bologna, where will spend 1 night.

Bologna’s wonders await as you prepare for another journey on the road, leaving the breathtaking surroundings of Venice behind. This drive usually takes around 1 hour 44 min. Bologna welcomes you with a multitude of unique vacation experiences.

Spend your afternoon discovering Pinacoteca Nazionale Di Bologna, an underrated art gallery known for its respected features. Next, continue your sightseeing at Piazza Santo Stefano, an often recommended public square.

If you're starting to feel hungry, this is a great time for a break at a nearby restaurant or cafe. When you're ready for more, stop by Two Towers and uncover the details of this stunning monument. Make sure to also explore Bologna Cathedral, an underrated church. For your last stop, consider Fountain Of Neptune, Bologna, a photogenic monument that many travelers find worth the detour.

At the end of the day, you will drive to Bologna, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a day of adventure, treat yourself to an exquisite dinner at one of Bologna's best restaurants.

Enjoy a delicious meal at Ristorante Ciacco, a top-rated dining destination in Bologna. If you're in the mood to try something new, consider Ristorante Ballarini, another top spot with a mouthwatering menu. You might also want to secure a reservation at Sfoglia Rina. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Bologna this evening.

After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at Bar Al Bricco D'oro, a well-loved spot among locals and tourists. Or, head to Bar Freud E Squisito. This bar boasts a welcoming environment that is perfect for winding down. You could also continue your night at Osteria Del Sole, another top-rated place in the area.

Relax and look forward to more memorable moments to come!

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Day9

Day 9

  • Bologna
  • Modena
  • Assisi
  • Pescara
  • More

Drive 572 km, 6 hours 47 min

  • Museo Stanguellini
  • Basilica of San Francesco d'Assisi
  • Chiesa di San Pietro
  • More

Your itinerary for day 9 of your road trip in Italy includes 3 stops and features some of the highlights of Modena, Santa Maria degli Angeli, and Valecchie. At the end of the day, enjoy the comforts of a top-rated hotel in Pescara, where you'll spend 1 night.

When you’re ready to jump back into the car and say goodbye to Bologna, you’ll hit the road in the direction of Modena. This drive usually takes around 47 min.

Our first attraction recommendation in Modena is Museo Stanguellini, a beloved museum that draws attention for its photogenic features.

Santa Maria degli Angeli’s wonders await as you prepare for another journey on the road, leaving the breathtaking surroundings of Modena behind. This drive usually takes around 3 hours 12 min. Santa Maria degli Angeli welcomes you with a multitude of unique vacation experiences.

Enjoy sightseeing at your own pace and allow yourself time to explore the beautiful surroundings. Take your self-guided tour to Basilica Of San Francesco D'assisi, a notable church that everyone visiting Santa Maria degli Angeli should see.

When you’re ready to jump back into the car and say goodbye to Valecchie, you’ll hit the road in the direction of Pescara. This drive usually takes around 2 hours 40 min.

Savor the day by heading to Chiesa Di San Pietro, a beloved church that draws visitors from near and far.

When you’re done exploring for the day, you’ll drive to your hotel in Pescara. Check in and relax before you head out to tour the city.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Pescara. Enjoy a relaxing evening as you savor delicious local cuisine.

Make sure to reserve a table at Ciacco, an iconic dining spot in Pescara. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Bar Sara, a popular restaurant in Pescara. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Ristorante Franco, a hidden gem nestled in Pescara. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

After your delicious meal, get a taste of the vibrant nightlife with a visit to Bar Napoli, known for its inviting atmosphere. Bar Supermarket is another great option if you’re looking for a place to get the night started. Similarly, Post Bar provides a great setting to enjoy the night away.

Take some time to reflect on your day and savor another beautiful night in Italy.

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Day10

Day 10

  • Pescara - Departure day
  • More
  • Nature Reserve Pineta Dannunziana
  • More

Day 10 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Pescara before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, we recommend visiting Nature Reserve Pineta Dannunziana, a romantic nature reserve before you head out.

Make the most of your final day in Italy by visiting Pescara’s iconic markets and shopping establishments in the buzzing Centro Commerciale Pescara Porta Nuova. Secure the perfect souvenirs for your family and friends back home or buy yourself a remembrance of your amazing vacation.

Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Pescara.

You’ll then say farewell to Pescara. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!

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Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

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Your trip is protected, personalized, and priced right. No surprises, no stress.

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