10-Day Italy Self-Drive Road Trip With Itinerary from Rome to Florence and Venice

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Explore the best of Italy on a 10-day road trip! Uncover hidden gems and experience the rich culture firsthand as you journey through Rome, Florence, Pisa, Monterosso al Mare, Vernazza, Riomaggiore, Manarola, Corniglia, Venice, and Orvieto. This road trip itinerary in Italy seamlessly combines exploration with relaxation.

This perfectly planned road trip itinerary in Italy takes you through some of the best places to see in the country. You will spend 3 nights in Rome, 2 nights in Florence, 2 nights in San Bernardino, and 2 nights in Venice. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Rome, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Trevi Fountain and Colosseum are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Pantheon, learn more about the unique Piazza Navona, and immerse yourself in the vibrant atmosphere of Piazza San Marco.

As you hit the open road and drive through Rome, Florence, Pisa, Monterosso al Mare, Vernazza, Riomaggiore, Manarola, Corniglia, Venice, and Orvieto, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.

Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!

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Itinerary summary

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Days
Destination
Attractions
Overnight
Day
City & Overnight
Attractions
Palatine Hill
ColosseumRoman ForumTrevi FountainSpanish StepsPiazza NavonaTrastevere
piazzale MichelangeloBasilica of Santa Croce in FlorenceFountain of NeptuneUffizi GalleryPonte Vecchiopiazza della Signoria
The Boboli GardensCathedral of Santa Maria del FioreGalleria dell'AccademiaCentral MarketBasilica of Santa Maria NovellaOltrarno
Campo santoPiazza del Duomo, PisaLeaning Tower of PisaKnights' SquareParrocchia di S. Giovanni BattistaChurch of St. Margaret of Antioch
RiomaggioreCastle of RiomaggiorePresepe di ManarolaManarola Overlook ViewpointCinque Terre National ParkScalinata Lardarina

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Day 1

Day 1

  • Rome - Arrival day
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  • Palatine Hill
  • More

Say hello to Rome! Your exciting road trip through Italy is just about to start. Navigating the top places to see in the region is a breeze with a car. The rental vehicle of your choice will be ready for pickup upon your arrival in the city. You will stay in Rome for 2 nights before you continue your adventure!

Rome is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Palatine Hill, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

As afternoon approaches, head to your chosen hotel in Rome. Check-in typically starts around 2 to 4 PM at hotels in Italy. We recommend staying at a hotel in a central location for easy access to the best attractions, restaurants, and bars in the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Rome, it's often a good idea to reserve a table in advance.

Have a fantastic dining experience at La Bottega Roma, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Pasta In Corso offers an enticing alternative with its varied menu. Additionally, Trattoria Vecchia Roma is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Rome.

Let the evening flow smoothly from dinner to drinks at La Botticella Of Poggi Giovanni, a top-rated bar in the area. For other recommendations, Almalu Trastevere provides a perfect setting for rounding out your night with style and great drinks. Likewise, Bar Viminale Di Pepi Maurilio offers a memorable night with diverse drink options and excellent service.

Raise a toast to the start of your 10-day road trip in Italy!

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Day 2

Day 2

  • Rome
  • More

Drive 6 km, 1 hour 24 min

  • Colosseum
  • Roman Forum
  • Trevi Fountain
  • Spanish Steps
  • Piazza Navona
  • Trastevere
  • More

Day 2 offers a multitude of experiences. You will stay in Rome for 1 night more, offering you enough time to explore at a relaxed pace.

Make sure to visit Trastevere, a popular neighborhood in Rome. Spend some time wandering around the area and soak in its distinctive charm. You’ll also discover that several of the city’s must-see attractions are just around the corner.

Enjoy the perfect balance of relaxation and exploration in Rome today. One of the most wondrous attractions included on the itinerary is Colosseum. This culturally significant archeological site will help you start your sightseeing on top. Then, take a leisurely stroll to Roman Forum and learn what makes this awe-inspiring archeological site unique.

Throughout the day, make sure to take breaks to appreciate the surroundings. Next up, visit the wondrous Trevi Fountain. After exploring the monument, head to Spanish Steps. This extraordinary public square is a highlight in Rome. Lastly, don’t forget to check out the iconic Piazza Navona. Enjoy exploring this incredible public square at your own pace.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

Visit Via del Corso in Rome for an unforgettable shopping experience. Browse unique and stores, each offering delightful surprises. Find unique souvenirs or items to take home. After shopping, explore what Via del Corso has to offer, including attractions, essential services, and vibrant community activities.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Rome. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Treat yourself to a delightful dinner at RomAntica, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Coso Ristorante? It's another excellent option with a diverse menu. Consider reserving a table at DEROMA - Farine Romane as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Rome.

Continue the enjoyment post-dinner at Sant' Eustachio Caffè, a cherished local gathering spot renowned for its welcoming atmosphere. Similarly, Yellowsquare Rome offers a vibrant space for indulging in well-crafted drinks and engaging conversation. You may also want to check out Caffè Portofino. This bar is a favorite among both locals and visitors looking for a delightful evening out filled with laughter and fun.

Savor another day of unforgettable experiences in Italy!

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Day 3

Day 3

  • Rome
  • Florence
  • More

Drive 281 km, 3 hours 47 min

  • piazzale Michelangelo
  • Basilica of Santa Croce in Florence
  • Fountain of Neptune
  • Uffizi Gallery
  • Ponte Vecchio
  • piazza della Signoria
  • More

On day 3 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Florence. In the evening, you’ll end up in Florence, where you will stay for 2 nights.

Today’s route brings fun adventures, romantic experiences, and scenic views. The first attraction of today is Piazzale Michelangelo. This widely recognized observation deck is an enchanting place to see in Rome. Continue your discovery at Basilica Of Santa Croce In Florence, a photogenic church with stories to tell.

As you stroll around Rome, take in the distinct atmosphere and learn what makes this city so unique. Maximize your sightseeing with a visit to Fountain Of Neptune. This underrated monument offers a masterful encounter with Rome. Uffizi Gallery is the last of our recommendations for today. Whether you decide to get entrance tickets for all attractions or you prefer admiring from a distance, amazing experiences await on this day in Rome.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Florence. Florence offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Florence. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Treat yourself to a delicious dinner at Ristorante Oliviero 1962, an excellent option for tonight's dining. Looking for something different? Di Poneta Novoli offers a tantalizing alternative with its diverse menu. And don’t miss Caffe San Firenze. With its reputation for pleasing customers, it’s a fantastic choice for tonight in Florence.

After your delicious meal, get a taste of the vibrant nightlife with a visit to Manifattura, known for its inviting atmosphere. Se·sto On Arno Rooftop Bar is another great option if you’re looking for a place to get the night started. Similarly, Il Vinile provides a great setting to enjoy the night away.

Get a good night's sleep and look forward to another great day on the road in Italy!

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Day 4

Day 4

  • Florence
  • More

Drive 6 km, 1 hour 36 min

  • The Boboli Gardens
  • Cathedral of Santa Maria del Fiore
  • Galleria dell'Accademia
  • Central Market
  • Basilica of Santa Maria Novella
  • Oltrarno
  • More

Day 4 of your road trip across Italy promises a magnificent time exploring Florence. You have 1 night left in Florence. Take the opportunity to experience more of the best attractions and activities in the city.

At the top of the list of things to do today is to explore Oltrarno, a neighborhood that captures the true essence of Florence. Take your time to uncover its best sides and enjoy its proximity to many of the area’s best attractions.

Get ready to discover some of the most iconic wonders in Florence, including a botanical garden, a church, an art gallery, a food market and much more! Start your day at The Boboli Gardens. This enchanting botanical garden is a popular place to see in Florence. Then, wander over to Cathedral Of Santa Maria Del Fiore. If culturally significant sites excite you, this church will be right up your alley. Nearby, you’ll also find Galleria Dell'accademia. This heritage-rich art gallery is a favorite among visitors.

Florence offers plenty to explore, ensuring every moment of your visit is filled with excitement and discovery. If you're up for more, Central Market is a popular spot in the city that will captivate you with its unique charm. When you’re done at the food market, don’t forget to check out the inviting Basilica Di Santa Maria Novella, Firenze (fi). Take a moment to appreciate the fascinating details of this captivating church in Florence.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

As dinnertime approaches, it's time to head out for a bite to eat in Florence. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Make sure to reserve a table at Ditta Artigianale, an iconic dining spot in Florence. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Trattoria Da Burde, a popular restaurant in Florence. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Casa Toscana, a hidden gem nestled in Florence. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

After enjoying a fulfilling meal, continue your evening at Bar 50 Rosso, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, Bitter Bar offers a welcoming atmosphere for easing into the nightlife. Similarly, Archea Brewery provides an excellent environment for a relaxed and enjoyable evening.

Celebrate another amazing day of your road trip adventure in Italy!

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Day 5

Day 5

  • Florence
  • More

Drive 207 km, 4 hours 25 min

  • Campo santo
  • Piazza del Duomo, Pisa
  • Leaning Tower of Pisa
  • Knights' Square
  • Parrocchia di S. Giovanni Battista
  • Church of St. Margaret of Antioch
  • More

Dive into day 5 of your remarkable road trip in Italy. Today you will explore Pisa, Monterosso al Mare, and Vernazza, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in San Bernardino. You’ll stay here for 2 nights.

Set out on a day brimming with family-friendly attractions, scenic views, and picturesque spots. Start at the increasingly popular Campo Santo, a culturally significant cemetery in Florence. Next, go to Piazza Del Duomo, Pisa.

After visiting Campo Santo and Piazza Del Duomo, Pisa, take time to explore Florence's streets and absorb its charm. Continue your sightseeing by heading to Leaning Tower Of Pisa. This picture-perfect monument offers a unique experience. Knights' Square is another noteworthy stop. End your self-guided sightseeing tour on top with a visit to Parrocchia Di S. Giovanni Battista, one of the most standout places to visit in Florence.

At the end of the day, you will drive to San Bernardino, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you explore more of San Bernardino, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Say good night to San Bernardino and look forward to another great day of your road trip in Italy!

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Day 6

Day 6

San Bernardino, Riomaggiore, Manarola, and Corniglia

Drive 33 km, 1 hour 51 min

  • Riomaggiore
  • Castle of Riomaggiore
  • Presepe di Manarola
  • Manarola Overlook Viewpoint
  • Cinque Terre National Park
  • Scalinata Lardarina
  • More

On day 6 of your road trip, you’ll start and end your day in San Bernardino, where you'll stay for 1 night more.

A blend of family-friendly attractions, romantic experiences, and scenic views await you in San Bernardino on today’s itinerary. First up is the often recommended point of interest, Riomaggiore. Afterward, continue to Castle Of Riomaggiore.

As you explore San Bernardino’s charming streets, take in the lively atmosphere and get to know the character of the village. Next, make your way to Presepe Di Manarola. This underrated art installation is an essential stop that should not be missed. Following that, head to Manarola Overlook Viewpoint, another must-visit site that will enhance your experience. Lastly, visit Cinque Terre National Park and learn why this national park is renowned as one of the village's most interesting attractions.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in San Bernardino.

As you explore more of San Bernardino, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in Italy.

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Day 7

Day 7

  • Venice
  • More

Drive 390 km, 5 hours 9 min

  • Bridge of Sighs
  • Doge's Palace
  • St Mark's Basilica
  • St Mark's Campanile
  • Piazza San Marco
  • More

Embark on another extraordinary experience on day 7 of your road trip in Italy. Today, you will make 1 stop and experience some of the highlights of Venice. At the end of the day, you will enjoy the comforts of a top-rated hotel in Venice, which will be your home away from home for 2 nights.

Savor the day by visiting some of the best places to see in San Bernardino, including a monument, a palace, a church, a public square and much more! Start your adventure at Bridge Of Sighs. This interesting monument is a must-visit for travelers looking for a unique holiday experience. Make your way to Doge's Palace located in San Bernardino for an enchanting atmosphere.

Next, immerse yourself in the setting of St Mark's Basilica. Its UNESCO world heritage-designated features will captivate you. After the church, continue your tour of the city with a visit to St Mark's Campanile. This monument has an enchanting appeal. For a change of pace, head to Piazza San Marco. As one of the most iconic attractions in San Bernardino, this public square is an excellent place to end your self-guided tour.

When you’re done exploring for the day, you’ll drive to your hotel in Venice. Check in and spend some time relaxing before you head out to tour the city.

After a day of adventure, treat yourself to an exquisite dinner at one of Venice's best restaurants.

Make sure to reserve a table at Bauer Hotel, an iconic dining spot in Venice. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of L'Osteria Le Guglie, a popular restaurant in Venice. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Corner Pub, a hidden gem nestled in Venice. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Unwind after your meal by stepping into Al Parlamento. This venue is celebrated for its extensive drink selections and cozy vibes. Alternatively, The Caffe Rosso offers a dynamic and energetic atmosphere for a glass or two. Don’t overlook Adagio, another top-rated bar in the area.

Raise your glass to another unforgettable day in Italy!

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Day 8

Day 8

  • Venice
  • More

Drive 5 km, 1 hour 16 min

  • Santa Maria della Salute
  • Palazzo Contarini del Bovolo
  • Rialto Bridge
  • Grand Canal
  • Ca' Pesaro International Gallery of Modern Art
  • Cannaregio
  • More

On day 8 of your road trip, you will have an entire day to explore Venice. You’ll stay in Venice for 1 night and discover all the best things to see and do in the area.

One of the most iconic places you can visit today in Venice is Cannaregio. Allow yourself some time to leisurely explore this neighborhood and discover its unique quirks. You'll also find many of the best sightseeing spots nearby.

Set out on a day brimming with family-friendly attractions, romantic experiences, and breathtaking views. Start at the locally appreciated Santa Maria Della Salute, a romantic church in Venice. Next, go to Palazzo Contarini Del Bovolo.

After visiting Santa Maria Della Salute and Palazzo Contarini Del Bovolo, take time to explore Venice's streets and absorb its charm. Continue your sightseeing by heading to Rialto Bridge. This history-steeped historical landmark offers a unique experience. Grand Canal is another noteworthy stop. End your self-guided sightseeing tour on top with a visit to Ca' Pesaro International Gallery Of Modern Art, one of the most visually striking places to visit in Venice.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

As you explore more of Venice, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Treat yourself to a delicious dinner at Generator Venice, an excellent option for tonight's dining. Looking for something different? Nevodi offers a tantalizing alternative with its diverse menu. And don’t miss Ristorante La Piazza. With its reputation for pleasing customers, it’s a fantastic choice for tonight in Venice.

Let the evening flow smoothly from dinner to drinks at Il Mercante, a top-rated bar in the area. For other recommendations, The Irish Pub Venezia provides a perfect setting for rounding out your night with style and great drinks. Likewise, Ai Stagneri offers a memorable night with diverse drink options and excellent service.

Relax and recharge in preparation for another adventurous day in Italy!

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Day 9

Day 9

  • Venice
  • Rome
  • More

Drive 544 km, 6 hours 15 min

  • Orvieto subterranea
  • Torre del Moro Orvieto
  • Pozzo della Cava
  • More

Experience an unparalleled adventure on day 9 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 vibrant destinations - Orvieto. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Rome. You will spend 1 night here for some well-deserved relaxation.

Immerse yourself in Venice’s rich culture with today's sightseeing itinerary. Start your journey at Orvieto Underground. This history-steeped cave system is sure to ignite your curiosity. Next, dive into the picture-perfect features of Torre Del Moro Orvieto, a must-visit monument in the town.

In between sights, stop by local stores, picturesque photo spots, and small eateries. When you’re ready for your next attraction, proceed to Pozzo Della Cava, a curiosity-inducing cave.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Rome. Rome offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As dinnertime approaches, it's time to head out for a bite to eat in Rome. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Savor the flavors at Hotel de Russie, a top pick for dinner tonight. Alternatively, La Taverna Italiana beckons with its unique menu offerings. Also, consider The Parrot Bar. With its consistent customer satisfaction, it’s an excellent option for dining in Rome tonight.

Continue your evening by exploring the vibrant nightlife scene at The Apartment Bar Roma, a prime destination for a thrilling night out. Also, don’t forget to check out Hotel Hassler Roma, a bar that offers unique local touches.

Raise your glass and celebrate another amazing day of your road trip in Italy!

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Day 10

Day 10

  • Rome - Departure day
  • More
  • Pantheon
  • More

Day 10 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Rome before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, we recommend visiting Pantheon, a culturally significant monument before you head out.

Maximize your last day in Italy and go on a shopping spree in Rome’s shopping center, the lively Via del Corso. Browse for souvenirs to remind you of your wonderful journey in Italy.

Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Rome.

Enjoy a lovely meal at Sofitel Roma Villa Borghese, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Centro is another top choice with a popular menu.

You’ll then say farewell to Rome. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!

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