10-Day Italy Self-Drive Road Trip With Itinerary from Rome to Florence and Venice

1 / 94
Photo of piazza de spagna in Rome, Italy.
Perfect travel plans
Everything included
Fully customizable

Description

Included

Flights
Hotel
Select dates
Car rental
Select dates
Tours & tickets
Select dates
Travel plan
From A to Z
Travel agent
24/7 fast service

Description

Escape the ordinary with this exciting 10-day road trip through Italy. Explore diverse landscapes, discover lively cities, and prepare for an unforgettable journey!

This perfectly planned road trip itinerary takes you through some of the best places to see in Italy. You will spend 3 nights in Rome, 2 nights in Florence, 2 nights in San Bernardino, and 2 nights in Venice. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Rome, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Trevi Fountain and Colosseum are just a couple of the bucket-list attractions that await your discovery.

As you hit the open road and drive through Rome, Florence, Pisa, Riomaggiore, Manarola, Corniglia, Vernazza, Venice, Bologna, and Orvieto, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.

Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!

Read more

Travel details

Set your travel details to find the best price

Flights

Round trip
Round trip
Travel dates

Travelers

Rooms

Flights

Compare and choose from the best flights to Rome

Car

Choose from the best car rental deals or see all options

Driver’s age is 30 - 65
I live in
Pick-up: 10:00
Drop-off: 10:00

Personalize your itinerary

Customize tours under each day and destination

Day1

Day 1

  • Rome - Arrival day
  • More
  • Palatine Hill
  • More

Welcome to Rome, the perfect starting point for your road trip in Italy! Pick up your rental car and let the adventure begin. You will spend 2 nights discovering what to see in Rome before embarking on the next leg of your journey.

Rome is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Palatine Hill. Taking a stroll in the city center is a great alternative. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

As afternoon approaches, head to your chosen hotel in Rome. Check-in typically starts around 2 to 4 PM at hotels in Italy. We recommend staying at a central location for easy access to key areas in the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Rome, it's often a good idea to reserve a table in advance.

Enjoy a delicious meal at La Bottega Roma, a highly-rated dining destination in Rome. If you're eager to try something different, consider Pasta In Corso, another top spot with a tantalizing menu. You might also want to secure a reservation at Trattoria Vecchia Roma. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Rome this evening.

After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at La Botticella Of Poggi Giovanni, a well-loved spot among locals and tourists. Or, head to Almalu Trastevere. This bar boasts a welcoming environment that is perfect for winding down. You could also continue your night at Bar Viminale Di Pepi Maurilio, another top-rated place in the area.

Raise a toast to the start of your 10-day road trip in Italy!

Read more
Day2

Day 2

  • Rome
  • More

Drive 6 km, 1 hour 24 min

  • Colosseum
  • Roman Forum
  • Trevi Fountain
  • Spanish Steps
  • Piazza Navona
  • Trastevere
  • More

On day 2 of your road trip, you will have an entire day to discover what to see in Rome. You’ll stay in Rome for 1 night.

Rome is brimming with adventures. Trastevere is a neighborhood that stands out as one of the must-see places in Rome. Take a moment to explore its distinct atmosphere, and don’t miss the popular sightseeing spots just a short walk away.

Catch Colosseum before the crowds roll in. This breathtaking archeological site is sure to ignite your curiosity. Next, dive into the historic features of Roman Forum, a must-visit archeological site in the city.

In between sights, stop by local stores, picturesque photo spots, and small eateries. When you’re ready for your next attraction, proceed to Trevi Fountain, a wondrous monument. For a change of scene, check out Spanish Steps, known for its visually striking features. We also recommend visiting Piazza Navona. This public square is a must for anyone looking to experience the city to the fullest.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

After a day of adventure, treat yourself to an exquisite dinner at one of Rome's best restaurants.

Treat yourself to a wonderful meal at RomAntica, a top-rated dining spot in Rome. If you're in the mood for something new, try Coso Ristorante, another premier location with a delectable menu. You might also want to book a table at DEROMA - Farine Romane. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Rome.

After savoring a delicious meal, step into the vibrant nightlife at Sant' Eustachio Caffè, where the evening is just getting started. In the same way, Yellowsquare Rome offers a unique charm perfect for experiencing the local bar scene in Rome. Caffè Portofino is another top-recommended bar that is sure to get you into the mood for some dancing and celebrating.

Get a good night's sleep and look forward to another great day on the road in Italy!

Read more
Day3

Day 3

  • Rome
  • Florence
  • More

Drive 281 km, 3 hours 45 min

  • piazzale Michelangelo
  • Basilica of Santa Croce in Florence
  • Uffizi Gallery
  • Ponte Vecchio
  • piazza della Signoria
  • More

Dive into day 3 of your remarkable road trip in Italy. Today you'll explore 1 destination, including Florence. At the end of the day, you’ll unwind at one of the finest accommodations in Florence, where you'll spend 2 nights.

It’s time to gear up for the next part of your road trip adventure. Under favorable conditions, your drive to Florence may take around 3 hours 6 min. Upon your arrival in Florence, you’ll be greeted with the opportunity to do some sightseeing and exploring.

One of our top recommendations for your sightseeing is Piazzale Michelangelo. Spend some time admiring the history-steeped features of the observation deck before you continue to your next stop. Then, head to Basilica Of Santa Croce In Florence. This interesting church is a traveler-favorite in the city.

If you're keen to see more, continue to Uffizi Gallery. Feed your curiosity by learning something new about the art gallery. Next, take your journey to Ponte Vecchio, a wondrous historical landmark. Conclude your sightseeing at Piazza Della Signoria, known for its romantic features.

When you’re done exploring for the day, you’ll drive to your hotel in Florence. Check in and relax before you head out to tour the city.

Florence is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Florence.

Make sure to reserve a table at Ristorante Oliviero 1962, an iconic dining spot in Florence. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Di Poneta Novoli, a popular restaurant in Florence. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Caffe San Firenze, a hidden gem nestled in Florence. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Keep the excitement of the evening going by visiting a bar or two. Manifattura is an excellent place to start. You could also check out Se·sto On Arno Rooftop Bar, offering a different kind of charm. A last recommendation for the day is Il Vinile. This bar promises an enjoyable experience with tasty drinks and a vibrant setting.

Take some time to reflect on your day and savor another beautiful night in Italy.

Read more
Day4

Day 4

  • Florence
  • More

Drive 4 km, 1 hour 3 min

  • Palazzo Pitti
  • Cathedral of Santa Maria del Fiore
  • Galleria dell'Accademia
  • Central Market
  • Basilica of Santa Maria Novella
  • Oltrarno
  • More

Day 4 of your road trip across Italy promises a magnificent time exploring what to see in Florence. You have 1 night left in Florence. Take the opportunity to experience more of the best attractions and activities in the city.

Oltrarno is one of the highlights of today. Take your time exploring this iconic neighborhood in Florence, which offers a perfect blend of history and culture. Plus, it's close to many must-see landmarks in the city.

Pitti Palace leaves a lasting impression. This palace is one of the most popular places to visit in Florence. Next, head to Cathedral Of Santa Maria Del Fiore, an extraordinary church, known for its visually striking features.

In between the sights, don’t hesitate to take small detours to explore local stores and eateries. When you’re ready to continue your adventure, head to Galleria Dell'accademia. This standout art gallery is a highly recommended experience. Nearby, you'll also find Central Market and Basilica Di Santa Maria Novella, Firenze (fi) Visit these for an interesting touch to your journey.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Florence. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Don’t miss out on dining at Ditta Artigianale, a top-rated dining destination in Florence. If you're in the mood to try something new, consider Trattoria Da Burde, another top spot with a mouthwatering menu. You might also want to secure a reservation at Casa Toscana. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Florence this evening.

After enjoying a fulfilling meal, continue your evening at Bar 50 Rosso, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, Bitter Bar offers a welcoming atmosphere for easing into the nightlife. Similarly, Archea Brewery provides an excellent environment for a relaxed and enjoyable evening.

Take some time to reflect on your day and savor another beautiful night in Italy.

Read more
Day5

Day 5

  • Florence
  • Pisa
  • Riomaggiore
  • More

Drive 195 km, 3 hours 15 min

  • Pisa Cathedral
  • Piazza del Duomo, Pisa
  • Leaning Tower of Pisa
  • Knights' Square
  • Lungarni di Pisa
  • Santuario di Nostra Signora di Montenero
  • More

On day 5 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 2 destinations, including Pisa and Riomaggiore. When you’re not sightseeing, take time to relax at your chosen hotel in San Bernardino, where you’ll be staying for 2 nights.

Embrace the thrill of the open road as you wave goodbye to Florence and set your GPS to Pisa. While on the road, immerse yourself in your favorite road trip tunes or sample the sounds from a local radio station. This car ride usually takes around 1 hour 15 min. Upon reaching Pisa, unwind, observe, and explore. The best things to do, see, and eat are waiting for you.

Spend your afternoon discovering Pisa Cathedral, a frequently visited church known for its picture-perfect features. Next, continue your sightseeing at Piazza Del Duomo, Pisa, a timeless public square.

If you're starting to feel hungry, this is a great time for a break at a nearby restaurant or cafe. When you're ready for more, stop by Leaning Tower Of Pisa and uncover the details of this noteworthy monument. Make sure to also explore Knights' Square, a beloved public square. For your last stop, consider Lungarni Di Pisa, a romantic street that many travelers find worth the detour.

Riomaggiore’s wonders await as you prepare for another journey on the road, leaving the breathtaking surroundings of Pisa behind. This drive usually takes around 1 hour 17 min. Riomaggiore welcomes you with a multitude of unique vacation experiences.

Enjoy sightseeing at your own pace and allow yourself time to explore the beautiful surroundings. Take your self-guided tour to Nostra Signora Di Montenero, an intriguing church that everyone visiting Riomaggiore should see.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in San Bernardino. San Bernardino offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in San Bernardino. Enjoy a relaxing evening as you savor delicious local cuisine.

Raise your glass to another unforgettable day in Italy!

Read more
Day6

Day 6

  • Riomaggiore
  • Manarola
  • Corniglia
  • More

Drive 32 km, 1 hour 50 min

  • Riomaggiore
  • Castle of Riomaggiore
  • Manarola Overlook Viewpoint
  • Cinque Terre National Park
  • More

On day 6 of your road trip, you'll get the chance to experience Riomaggiore, Manarola, Corniglia, and Vernazza. At the end of the day, you'll drive back to San Bernardino, where you still have 1 night left to stay.

Set your GPS to Riomaggiore and hit the road. Expect a journey of approximately 27 min without stops. Soak in the beautiful landscapes as you drive and look forward to exploring your next destination. Riomaggiore beckons with new experiences!

Enjoy sightseeing at your own pace and allow yourself time to explore the beautiful surroundings. Take your self-guided tour to Riomaggiore, an increasingly popular point of interest that everyone visiting Riomaggiore should see. Next, head to Castle Of Riomaggiore. This stunning castle is one of the most worthwhile attractions in the region.

Corniglia’s wonders await as you prepare for another journey on the road, leaving the breathtaking surroundings of Manarola behind. This drive usually takes around 15 min. Corniglia welcomes you with a multitude of unique vacation experiences.

Set out on a self-guided sightseeing tour at Manarola Overlook Viewpoint and explore the romantic features.

When you’re ready to jump back into the car and say goodbye to Manarola, you’ll hit the road in the direction of Corniglia. This drive usually takes around 15 min.

For a more meaningful self-guided tour of the village's best attractions, visit Cinque Terre National Park, a well-known national park that is sure to impress. Take in the surroundings and enjoy the freedom of exploring at your own pace before you continue your journey.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in San Bernardino.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in San Bernardino. Enjoy a relaxing evening as you savor delicious local cuisine.

Savor another day of unforgettable experiences in Italy!

Read more
Day7

Day 7

  • Venice
  • More

Drive 390 km, 5 hours 9 min

  • Bridge of Sighs
  • Doge's Palace
  • St Mark's Basilica
  • St Mark's Campanile
  • Piazza San Marco
  • More

Your itinerary for day 7 of your road trip in Italy includes 1 stop and features some of the highlights of Venice. At the end of the day, enjoy the comforts of a top-rated hotel in Venice, where you'll spend 2 nights.

Venice’s wonders await as you prepare for another journey on the road, leaving the breathtaking surroundings of San Bernardino behind. This drive usually takes around 4 hours 49 min. Venice welcomes you with a multitude of unique vacation experiences.

When you're ready for some sights, head to Bridge Of Sighs, an interesting monument in Venice. Explore its UNESCO world heritage-listed features at your own pace before you continue your journey to your next attraction, Doge's Palace. This well-known palace is a top recommendation in the area.

When you’re ready to explore more, St Mark's Basilica is an excellent choice. Spend some time discovering what some claim to be the most UNESCO world heritage-designated church in the region. Next, continue your sightseeing at the curiosity-inducing St Mark's Campanile and discover what makes this monument unique. If you’re up for one more stop in the city, head to Piazza San Marco, a grand public square many travelers find the visit worthwhile.

At the end of the day, you will drive to Venice, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

Indulge in a memorable dining experience at one of Venice's most popular restaurants, and connect with friendly locals for a true cultural experience.

Enjoy a delicious meal at Bauer Hotel, a top-rated dining destination in Venice. If you're in the mood to try something new, consider L'Osteria Le Guglie, another top spot with a mouthwatering menu. You might also want to secure a reservation at Corner Pub. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Venice this evening.

Let the evening flow smoothly from dinner to drinks at Al Parlamento, a top-rated bar in the area. For other recommendations, The Caffe Rosso provides a perfect setting for rounding out your night with style and great drinks. Likewise, Adagio offers a memorable night with diverse drink options and excellent service.

Relax and look forward to more memorable moments to come!

Read more
Day8

Day 8

  • Venice
  • More

Drive 4 km, 56 min

  • Santa Maria della Salute
  • Peggy Guggenheim Collection
  • Gallerie dell'Accademia
  • Palazzo Contarini del Bovolo
  • Rialto Bridge
  • Grand Canal
  • More

Day 8 of your road trip will take you to the best attractions Venice has to offer. Cherish the 1 night you have left in the city and use the provided itinerary to discover what to see in Venice.

Make time for Santa Maria Della Salute, an up-and-coming church that is worthwhile a visit in the city. Nearby, you’ll find Peggy Guggenheim Collection, enchanting visitors with its enchanting appeal. Continue your exploration at Gallerie Dell'accademia. This art gallery is one of the city’s most curiosity-inducing spots.

Enjoy the freedom of exploring Venice at your own pace and find hidden gems along the way. If you want to see more picture-perfect spots, make sure to visit Palazzo Contarini Del Bovolo. After exploring the palace, head to the wondrous Rialto Bridge. Lastly, wrap up today’s self-guided sightseeing tour with a visit to Grand Canal, a place of UNESCO world heritage-designated interest in Venice.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Venice, it's often a good idea to reserve a table in advance.

Enjoy a delicious meal at Generator Venice, a top-rated dining destination in Venice. If you're in the mood to try something new, consider Nevodi, another top spot with a mouthwatering menu. You might also want to secure a reservation at Ristorante La Piazza. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Venice this evening.

Extend your evening after a delightful meal by visiting Il Mercante, which offers the perfect atmosphere for a night out. Moreover, The Irish Pub Venezia is another popular option for a drink or two. Likewise, Ai Stagneri also provides a great ambiance for reminiscing about the day and raising a toast to your vacation.

Savor another day of unforgettable experiences in Italy!

Read more
Day9

Day 9

  • Venice
  • Bologna
  • Orvieto
  • Rome
  • More

Drive 555 km, 6 hours 36 min

  • Two Towers
  • Palazzo del Podestà, Bologna
  • Piazza Maggiore
  • Torre dell'Orologio
  • Orvieto Cathedral
  • More

On day 9 of your road trip in Italy, your travel plans include 2 stops at the most scenic, wondrous, and interesting places in the region. Bologna and Orvieto are on today's agenda. In the evening, you’ll end up in Rome, where you will stay for 1 night.

Continue your road trip and head to your next destination, Bologna. This car ride takes around 1 hour 47 min.

Two Towers is an interesting monument we recommend visiting today. Discover its respected features before continuing your self-guided tour to Palazzo Del Podestà, Bologna, a symbolic palace that’s well-regarded in the area.

Next, stop by Piazza Maggiore, an awe-inspiring public square. While you’re nearby, don’t forget to visit Torre Dell'orologio, an instagrammable and truly unique monument.

Set your GPS to Orvieto and hit the road. Expect a journey of approximately 2 hours 57 min without stops. Soak in the beautiful landscapes as you drive and look forward to exploring your next destination. Orvieto beckons with new experiences!

Savor the day by heading to Orvieto Cathedral, a popular church that draws visitors from near and far.

When you’re done exploring for the day, you’ll drive to your hotel in Rome. Check in and relax before you head out to tour the city.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Rome. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Enjoy a delicious meal at Hotel de Russie, a highly-rated dining destination in Rome. If you're eager to try something different, consider La Taverna Italiana, another top spot with a tantalizing menu. You might also want to secure a reservation at The Parrot Bar. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Rome this evening.

After your delicious meal, get a taste of the vibrant nightlife with a visit to The Apartment Bar Roma, known for its inviting atmosphere. Hotel Hassler Roma is another great option if you’re looking for a place to get the night started.

As the sun sets, rest up and recharge for the next leg of your road trip in Italy.

Read more
Day10

Day 10

  • Rome - Departure day
  • More
  • Pantheon
  • More

Day 10 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Rome before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, begin at Pantheon. This timeless monument is a hotspot among locals.

For a last-minute shopping spree in Rome, Via del Corso is nearby. Enjoy a variety of retail stores, dining options, and essential services in one convenient location.

Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Rome.

You’ll then say farewell to Rome. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!

Read more

How it works

Book your journey with Europe’s biggest travel platform—expert itineraries, instant confirmation, and full flexibility with 24/7 support.

Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

We guarantee

Your trip is protected, personalized, and priced right. No surprises, no stress.

Similar travel packages

Discover other popular vacations in Italy

Link to appstore phone
Install Europe’s biggest travel app

Download Europe’s biggest travel marketplace to your phone to manage your entire trip in one place

Scan this QR code with your phone camera and press the link that appears to add Europe’s biggest travel marketplace into your pocket. Enter your phone number or email address to receive an SMS or email with the download link.