10-Day Italy Self-Drive Road Trip With Itinerary from Rome traveling north to Florence, Siena, La Spezia, and Venice
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Experience the freedom of the open road in Italy as you embark on an unforgettable 10-day road trip! This experience caters to every traveler, featuring destinations like Rome, Florence, Pisa, Siena, Castellina in Chianti, Corniglia, Manarola, Riomaggiore, La Spezia, Venice, and Verona.
This perfectly planned road trip itinerary in Italy takes you through some of the best places to see in the country. You will spend 3 nights in Rome, 2 nights in Florence, 2 nights in Siena, 1 night in La Spezia, and 1 night in Venice. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!
With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.
Upon arriving in Rome, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.
An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Trevi Fountain and Colosseum are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Pantheon, learn more about the unique Piazza Navona, and immerse yourself in the vibrant atmosphere of Rialto Bridge.
As you hit the open road and drive through Rome, Florence, Pisa, Siena, Castellina in Chianti, Corniglia, Manarola, Riomaggiore, La Spezia, Venice, and Verona, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.
Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.
This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.
The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!
Itinerary summary
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Day 1
- Rome - Arrival day
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- Palatine Hill
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Your road trip adventure in Italy begins as soon as you reach Rome and pick up your car. You’ll stay in Rome for 2 nights and explore the best things to see and do, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.
Rome is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Palatine Hill, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.
Find your way to your hotel in Rome. We recommend choosing a hotel in a central location for easy exploring. Check-in typically starts between 2 and 4 PM at hotels in Italy. Settle in and make plans for the evening.
As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Rome, it's often a good idea to reserve a table in advance.
Have a fantastic dining experience at La Bottega Roma, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Pasta In Corso offers an enticing alternative with its varied menu. Additionally, Trattoria Vecchia Roma is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Rome.
Explore the vibrant nightlife at La Botticella Of Poggi Giovanni after your meal, a hub for lively evenings and memorable moments. Or, head to Almalu Trastevere for a great selection of flavorful drinks and a charming setting. Furthermore, Bar Viminale Di Pepi Maurilio is perfect for those looking to extend their night with a touch of local flavor.
Raise a toast to the start of your 10-day road trip in Italy!
Day 2
- Rome
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Drive 6 km, 1 hour 24 min
- Colosseum
- Roman Forum
- Trevi Fountain
- Spanish Steps
- Piazza Navona
- Trastevere
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Day 2 of your road trip across Italy promises a magnificent time exploring Rome. You have 1 night left in Rome. Take the opportunity to experience more of the best attractions and activities in the city.
Set aside time today to explore Trastevere, a standout neighborhood that reflects the essence of the city. While you're there, you'll also be within reach of some of the city's top landmarks, making it easy to maximize your day.
Enjoy the perfect balance of relaxation and exploration in Rome today. One of the most globally renowned attractions included on the itinerary is Colosseum. This picture-perfect archeological site will help you start your sightseeing on top. Then, take a leisurely stroll to Roman Forum and learn what makes this culturally significant archeological site unique.
Throughout the day, make sure to take breaks to appreciate the surroundings. Next up, visit the timeless Trevi Fountain. After exploring the monument, head to Spanish Steps. This spectacular public square is a highlight in Rome. As your day continues, stop by Piazza Navona, known for its visually striking features.
Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.
Elevate your experience in Rome with a visit to the city's premier shopping location, Trastevere. Explore unique boutique shops and uncover hidden gems along the way. For a cultural touch, look for artisan crafts that perfectly capture the charm of Italy. After shopping, enjoy nearby attractions or simply people-watch and capture memorable photos.
As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Rome. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.
Enjoy a lovely meal at RomAntica, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Coso Ristorante is another top choice with a popular menu. You could also check for a table at DEROMA - Farine Romane. As an establishment that gains consistently high praises from customers, it’s an ideal choice in Rome tonight.
Following your dinner, dive into the local bar culture at Sant' Eustachio Caffè. Enjoy this evening's relaxed ambiance with delightful drinks. Alternatively, go to Yellowsquare Rome, the perfect place for those looking to experience the best of the nightlife. Similarly, Caffè Portofino provides excellent drinks and a great atmosphere, ensuring a memorable night out.
Raise your glass and celebrate another amazing day of your road trip in Italy!
Day 3
- Rome
- Florence
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Drive 281 km, 3 hours 51 min
- piazzale Michelangelo
- Basilica of Santa Croce in Florence
- Uffizi Gallery
- Ponte Vecchio
- Piazza della Repubblica
- piazza della Signoria
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On day 3 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Florence. In the evening, you’ll end up in Florence, where you will stay for 2 nights.
Discover a day packed with fun adventures, romantic experiences, and scenic views in Rome. Begin your sightseeing with Piazzale Michelangelo. This top-rated observation deck is one of the top attractions in the city. Proceed to Basilica Of Santa Croce In Florence, another must-visit attraction.
As you wander through the inviting streets of Rome, soak in the lively ambiance and take the opportunity to snap some photos. Next, head to Uffizi Gallery. This spectacular art gallery is a traveler-favorite. Not far away, you’ll find Ponte Vecchio, another key site on your sightseeing itinerary. Piazza Della Repubblica is yet another highly recommended place to visit nearby, offering plenty to discover for curious travelers. Conclude your day at Piazza Della Signoria and uncover why it's recognized as one of the city's most famous attractions.
After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Florence. Florence offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.
As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Florence. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.
Make sure to reserve a table at Ristorante Oliviero 1962, an iconic dining spot in Florence. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Di Poneta Novoli, a popular restaurant in Florence. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Caffe San Firenze, a hidden gem nestled in Florence. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.
Continue your lively evening at Manifattura, a perfect place for winding down or revving up the night, depending on which mood you’re in. Se·sto On Arno Rooftop Bar is another excellent bar that offers a great selection of drinks to suit any mood. If you prefer to go somewhere else, Il Vinile ensures a night out tailored to your taste.
Raise your glass and celebrate another amazing day of your road trip in Italy!
Day 4
- Florence
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Drive 196 km, 3 hours 5 min
- Palazzo Blu
- Knights' Square
- Palazzo della Carovana
- Leaning Tower of Pisa
- Pisa Cathedral
- Piazza del Duomo, Pisa
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On day 4 of your road trip, you’ll start and end your day in Florence, where you'll stay for 1 night more.
Today, you'll explore some of the most beautiful places in Florence, including an art gallery, a public square, a palace, a monument, a church and much more! Start your day with a visit to Palazzo Blu. This curiosity-inducing art gallery is a must-visit in the city. When you’re ready for your next discovery, continue to Knights' Square, which may be one of the most picture-perfect places you will experience today.
One of the best things about exploring Florence on a self-guided tour is that you set the pace. There’s plenty of time for detours and discovering hidden gems. When you’re ready for your next stop, make your way to Palazzo Della Carovana, an increasingly popular palace in the city. If you’re up for more discoveries, don’t forget to reserve some time for Leaning Tower Of Pisa and Pisa Cathedral. End your day with a visit to Piazza Del Duomo, Pisa, a timeless public square that’s sure to leave a lasting impression.
When you’re done exploring for the day, you’ll return to Florence and your accommodation.
After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Florence. Enjoy a satisfying meal that will recharge you for tonight's adventures.
Enjoy a lovely meal at Ditta Artigianale, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Trattoria Da Burde is another top choice with a popular menu. You could also check for a table at Casa Toscana. As an establishment that gains consistently high praises from customers, it’s an ideal choice in Florence tonight.
Let the evening flow smoothly from dinner to drinks at Bar 50 Rosso, a top-rated bar in the area. For other recommendations, Bitter Bar provides a perfect setting for rounding out your night with style and great drinks. Likewise, Archea Brewery offers a memorable night with diverse drink options and excellent service.
As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in Italy.
Day 5
- Florence
- Siena
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Drive 79 km, 1 hour 28 min
- Basilica of San Domenico
- Fontebranda
- Siena Cathedral
- Pubblico Palace
- piazza del Campo
- Tower of Mangia
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On day 5 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, Siena. When you’re not sightseeing, take time to relax at your selected hotel in Siena, where you’ll be staying for 2 nights.
Today’s itinerary in Florence covers several incredible sights, including a church, a historical landmark, a palace, a public square, a monument and much more! Start your adventure at Basilica Of San Domenico. This intriguing church is a place that is appreciated by travelers and locals alike. Next, immerse yourself in the heritage-rich wonders of Fontebranda, a must-see historical landmark in the city.
Consider stopping for a small bite to eat or a drink at a local eatery to keep your energy going. When you’re ready, continue your discovery with a visit to Siena Cathedral. This notable church offers an enriching experience. For a change of pace, head to Pubblico Palace, where you can take in breathtaking features. Conclude your self-guided sightseeing tour with a visit to Piazza Del Campo and Tower Of Mangia. These sights offer a fulfilling end to a perfect day.
At the end of the day, you will drive to Siena, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.
As you explore more of Siena, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.
Treat yourself to a delicious dinner at Enoteca I Terzi, an excellent option for tonight's dining. Looking for something different? Ristorante Tar-Tufo offers a tantalizing alternative with its diverse menu. And don’t miss Antica Trattoria Papei. With its reputation for pleasing customers, it’s a fantastic choice for tonight in Siena.
After your meal, keep the night alive at a bar like Meet Life Cafè, known for its lively atmosphere. Maudit Pub is another top recommendation that provides the perfect setting with well-crafted drinks and a welcoming ambiance. Similarly, Bar Impero Siena offers an excellent atmosphere for those looking to amp up the evening.
Take some time to reflect on your day and savor another beautiful night in Italy.
Day 6
- Siena
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Drive 76 km, 2 hours 7 min
- Winery San Giorgio a Lapi
- Castello di Brolio
- Poggio Amorelli
- Tumulo di Montecalvario
- Rocca di Castellina in Chianti
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Wake up to day 6 of your extraordinary road trip in Italy. With 1 night left in Siena, we encourage you to seize the day and discover the unexplored beauty of the city’s surroundings!
A blend of fun adventures, romantic experiences, and breathtaking views await you in Siena on today’s itinerary. First up is the locally appreciated winery, Winery San Giorgio A Lapi. Afterward, continue to Castello Di Brolio, a castle every traveler should visit.
As you explore Siena’s charming streets, take in the lively atmosphere and get to know the character of the city. Next, make your way to Poggio Amorelli. This increasingly popular winery is an essential stop. Following that, head to Tumulo Di Montecalvario, another must-visit site that will enhance your experience. Don’t forget to stop by Rocca Di Castellina In Chianti, an underrated castle in the city.
When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Siena.
After a day of adventure, treat yourself to an exquisite dinner at one of Siena's best restaurants.
Treat yourself to a wonderful meal at Osteria Quattro Venti, a top-rated dining spot in Siena. If you're in the mood for something new, try Fischi per Fiaschi, another premier location with a delectable menu. You might also want to book a table at Osteria da Divo. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Siena.
Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, Charlie Mixology Bar Di Aldinucci Riccardo stands out as an excellent choice for a post-dinner cocktail. Alternatively, Bar Pinacoteca offers an ideal atmosphere to enjoy the pleasures of the night. San Paolo Pub is also a great option that provides a perfect setting for a relaxing evening.
Savor another day of unforgettable experiences in Italy!
Day 7
- Siena
- La Spezia
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Drive 259 km, 4 hours 21 min
- Cinque Terre National Park
- Manarola Overlook Viewpoint
- Chiesa di San Lorenzo
- Riomaggiore
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Dive into day 7 of your remarkable road trip in Italy. Today you will explore Corniglia, Manarola, and Riomaggiore, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in La Spezia. You’ll stay here for 1 night.
Today’s route brings fun adventures, romantic experiences, and natural wonders. The first attraction of today is Cinque Terre National Park. This popular national park is a serene place to see in Siena. Continue your discovery at Manarola Overlook Viewpoint, an eye-catching observation deck with stories to tell.
As you stroll around Siena, take in the distinct atmosphere and learn what makes this village so unique. Maximize your sightseeing with a visit to Chiesa Di San Lorenzo. This frequently visited church offers a picture-perfect encounter with Siena. Next, make your way to Riomaggiore to add another highlight to your day. Whether you decide to get entrance tickets for all attractions or you prefer admiring from a distance, amazing experiences await on this day in Siena.
When you’re done exploring for the day, you’ll drive to your hotel in La Spezia. Check in and spend some time relaxing before you head out to tour the city.
After a day of adventure, treat yourself to an exquisite dinner at one of La Spezia's best restaurants.
Enjoy a delicious meal at The Colombaio Park, a top-rated dining destination in La Spezia.
Get a good night's sleep and look forward to another great day on the road in Italy!
Day 8
- La Spezia
- Venice
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Drive 366 km, 4 hours 32 min
- Bridge of Sighs
- Doge's Palace
- St Mark's Basilica
- Grand Canal
- Rialto Bridge
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Embark on another extraordinary experience on day 8 of your road trip in Italy. Today, you will make 1 stop and experience some of the highlights of Venice. At the end of the day, you will enjoy the comforts of a top-rated hotel in Venice, which will be your home away from home for 1 night.
Enjoy the perfect balance of relaxation and exploration in La Spezia today. One of the most captivating attractions included on the itinerary is Bridge Of Sighs. This majestic monument will help you start your sightseeing on top. Then, take a leisurely stroll to Doge's Palace and learn what makes this UNESCO world heritage-listed palace unique.
Throughout the day, make sure to take breaks to appreciate the surroundings. Next up, visit the interesting St Mark's Basilica. After exploring the church, head to Grand Canal. This increasingly popular street is a highlight in La Spezia. As your day continues, stop by Rialto Bridge, known for its grand features.
After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Venice. Venice offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.
After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Venice. Enjoy a satisfying meal that will recharge you for tonight's adventures.
Treat yourself to a wonderful meal at Bauer Hotel, a top-rated dining spot in Venice. If you're in the mood for something new, try L'Osteria Le Guglie, another premier location with a delectable menu. You might also want to book a table at Corner Pub. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Venice.
If you’re not ready to end the night just yet, Al Parlamento offers a perfect venue to relax and savor a drink. Similarly, The Caffe Rosso is well-suited for those looking to unwind in a social setting. Adagio is another excellent spot to enjoy a nightcap after a delightful meal.
Savor another day of unforgettable experiences in Italy!
Day 9
- Venice
- Rome
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Drive 632 km, 7 hours 4 min
- Ponte Pietra
- Scaliger Tombs
- piazza delle Erbe
- Verona Arena
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Experience an unparalleled adventure on day 9 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 vibrant destinations - Verona. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Rome. You will spend 1 night here for some well-deserved relaxation.
Venice is home to plenty of attractions that offer fun adventures, romantic experiences, and breathtaking views! Start at Ponte Pietra, a captivating historical landmark that is worthwhile a visit in the city. Nearby, you’ll find Scaliger Tombs, enchanting visitors with its heritage-rich appeal. Continue your exploration at Piazza Delle Erbe. This public square is one of the city’s most well-known spots.
Enjoy the freedom of exploring Venice at your own pace and find hidden gems along the way. If you want to see more picture-perfect spots, make sure to visit Verona Arena.
At the end of the day, you will drive to Rome, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.
As dinnertime approaches, it's time to head out for a bite to eat in Rome. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.
Enjoy a lovely dining experience at Hotel de Russie, a popular restaurant in Rome. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Rome at La Taverna Italiana, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated The Parrot Bar. It’s yet another ideal choice to enhance your time in Rome tonight.
Keep the excitement of the evening going by visiting a bar or two. The Apartment Bar Roma is an excellent place to start. You could also check out Hotel Hassler Roma, offering a different kind of charm.
Head back to your accommodation in Rome and get some rest in preparation for another magical day of your road trip in Italy!
Day 10
- Rome - Departure day
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- Pantheon
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Day 10 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Rome before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.
If you're up for some more sightseeing, begin at Pantheon. This iconic monument is a popular place to see in the city.
As your final day in Italy unfolds, enjoy a last-minute shopping spree in Rome's best shopping area, Galleria San Pietro. Enjoy finding the perfect gift or keepsake to remind you of your wonderful trip to Italy.
Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Rome.
You’ll then say farewell to Rome. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!
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