10-Day Italy Self-Drive Road Trip With Itinerary from Venice to Florence, Lucca, San Gimignano, and Rome

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Explore the best of Italy on a remarkable 10-day road trip! Combine exploration with relaxation on a self-drive tour featuring Venice, Murano, Florence, Pisa, Lucca, Riomaggiore, Manarola, Corniglia, Levanto, Siena, San Gimignano, Rome, and Santa Maria degli Angeli.

This perfectly planned road trip itinerary takes you through some of the best places to see in Italy. You will spend 3 nights in Venice, 1 night in Florence, 2 nights in Lucca, 1 night in San Gimignano, and 2 nights in Rome. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Venice, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Trevi Fountain and Colosseum are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Pantheon, learn more about the unique Piazza Navona, and immerse yourself in the vibrant atmosphere of Piazza San Marco.

As you hit the open road and drive through Venice, Murano, Florence, Pisa, Lucca, Riomaggiore, Manarola, Corniglia, Levanto, Siena, San Gimignano, Rome, and Santa Maria degli Angeli, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.

Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!

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Driver’s age is 30 - 65
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Day 1

Day 1

  • Venice - Arrival day
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  • Rialto Bridge
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Welcome to Venice, the perfect starting point for your road trip in Italy! Pick up your rental car and let the adventure begin. You will spend 2 nights discovering what to see in Venice before embarking on the next leg of your journey.

Venice is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Rialto Bridge. Taking a stroll in the city center is a great alternative. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Find your way to your hotel in Venice. We recommend choosing a hotel in a central location for easy exploring. Check-in typically starts between 2 and 4 PM at hotels in Italy. Settle in and make plans for the evening.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Venice, it's often a good idea to reserve a table in advance.

Treat yourself to a wonderful meal at Bauer Hotel, a top-rated dining spot in Venice. If you're in the mood for something new, try L'Osteria Le Guglie, another premier location with a delectable menu. You might also want to book a table at Corner Pub. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Venice.

To truly maximize your evening out, consider visiting Al Parlamento after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to The Caffe Rosso, another bar with an inviting ambiance. Similarly, Adagio also offers a great atmosphere, ensuring a night filled with enjoyment and relaxation.

Raise a toast to the start of your 10-day road trip in Italy!

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Day 2

Day 2

  • Venice
  • More

Drive 14 km, 34 min

  • Piazza San Marco
  • St Mark's Campanile
  • St Mark's Basilica
  • Doge's Palace
  • Bridge of Sighs
  • Murano
  • More

Wake up to day 2 of your road trip in Italy. On this day, you’ll embark on an exciting expedition discovering the enchanting sights and activities of Venice and Murano. With 1 night to stay in Venice, we encourage you to seize the day and discover the unexplored beauty of the city’s surroundings!

Piazza San Marco is must-visit public square and a great option for a daytime tour of the area. Continue your journey to St Mark's Campanile, a frequently visited monument, located just a leisurely stroll away. Next, head to St Mark's Basilica, an inviting church, also available for your discovery today.

Each stop on today’s itinerary promises to leave you with lasting memories and a deeper appreciation for Venice. When you're ready, let your sightseeing route take you to the notable Doge's Palace. If you’re looking for more, Bridge Of Sighs is also a locally renowned attraction that is worthwhile a visit. Lastly, don’t miss Murano, a place of enchanting interest in the city.

When you’re done exploring for the day, you’ll return to Venice and your accommodation.

Indulge in a memorable dining experience at one of Venice's most popular restaurants, and connect with friendly locals for a true cultural experience.

Make sure to reserve a table at Generator Venice, an iconic dining spot in Venice. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Nevodi, a popular restaurant in Venice. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Ristorante La Piazza, a hidden gem nestled in Venice. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Round off your dining experience by visiting Il Mercante, a prime location for a drink. Alternatively, explore the distinctive characteristics of The Irish Pub Venezia, a bar catering to every mood and preference. Ai Stagneri likewise offers a unique atmosphere, perfect for a memorable night out.

Take some time to reflect on your day and savor another beautiful night in Italy.

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Day 3

Day 3

  • Venice
  • Florence
  • More

Drive 263 km, 3 hours 20 min

  • Ponte Vecchio
  • Uffizi Gallery
  • Basilica of Santa Croce in Florence
  • Hercules and Cacus
  • piazza della Signoria
  • More

Experience an unparalleled adventure on day 3 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 place, which are Florence. At the end of the day, you will retreat to the hotel of your choice in Florence, where will spend 1 night.

Ponte Vecchio is perfect for a self-paced visit during the day. This enchanting historical landmark is sure to impress. Next on your list is Uffizi Gallery, another must-visit landmark and famous art gallery renowned for its romantic features.

While exploring and sightseeing, take time to savor the culture of Venice by sampling some local delicacies. When you’re ready for more sightseeing, head to Basilica Of Santa Croce In Florence. This instagrammable church is an essential place to visit for anyone looking for the full Venice experience. We also recommend visiting Hercules And Cacus, an underrated sculpture. Nearby, you'll also find Piazza Della Signoria, ready to add charm to your journey.

At the end of the day, you will drive to Florence, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Florence. Enjoy a relaxing evening as you savor delicious local cuisine.

Have a fantastic dining experience at Ristorante Oliviero 1962, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Di Poneta Novoli offers an enticing alternative with its varied menu. Additionally, Caffe San Firenze is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Florence.

Keep the excitement of the evening going by visiting a bar or two. Manifattura is an excellent place to start. You could also check out Se·sto On Arno Rooftop Bar, offering a different kind of charm. A last recommendation for the day is Il Vinile. This bar promises an enjoyable experience with tasty drinks and a vibrant setting.

Celebrate another amazing day of your road trip adventure in Italy!

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Day 4

Day 4

  • Florence
  • Lucca
  • More

Drive 109 km, 2 hours 13 min

  • Cathedral of Santa Maria del Fiore
  • Galleria dell'Accademia
  • Piazza del Duomo, Pisa
  • Leaning Tower of Pisa
  • Walls of Lucca
  • More

Dive into day 4 of your remarkable road trip in Italy. Today you'll explore 3 destinations, including Florence, Pisa, and Lucca. At the end of the day, you’ll unwind at one of the finest accommodations in Lucca, where you'll spend 2 nights.

To truly experience Florence, make sure to drop by Cathedral Of Santa Maria Del Fiore. This top-rated church is a must-visit for anyone seeking a unique vacation experience. Another sight you shouldn’t miss is Galleria Dell'accademia, one of the city’s best highlights.

Next, check out Piazza Del Duomo, Pisa, one of the most world-famous places to see in Florence. This public square is a favorite among locals and travelers alike. Enjoy some downtime and refreshments before continuing to your next stop, Leaning Tower Of Pisa. Wander around and soak in the culturally significant atmosphere this monument offers. Then, head to Mura Di Lucca, a top-rated historical landmark that adds another dimension to your day.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Lucca. Lucca offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

Indulge in a memorable dining experience at one of Lucca's most popular restaurants, and connect with friendly locals for a true cultural experience.

Make sure to reserve a table at Gli Orti di Via Elisa, an iconic dining spot in Lucca. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Bar Caffè Ristretto, a popular restaurant in Lucca. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Ristorante Schiaffino, a hidden gem nestled in Lucca. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Cap off your dinner by heading to Lebowski - Cocktail Bar, ideal for a leisurely evening with a drink in hand. Blend is another bar that offers an enjoyable setting. Similarly, Franklin'33 is also a popular place to go on a night out, perfect for relaxing and socializing.

Take some time to reflect on your day and savor another beautiful night in Italy.

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Day 5

Day 5

  • Lucca
  • More

Drive 226 km, 4 hours 24 min

  • Riomaggiore
  • Manarola Overlook Viewpoint
  • Cinque Terre National Park
  • Saint Andrew's Church
  • More

On day 5 of your road trip in Italy, you’ll start and end your day in Lucca, but spend the day exploring what’s beyond the city. Since you still have 1 night to spend in Lucca, there’s no need to rush. Experience Riomaggiore, Manarola, Corniglia, and Levanto to the fullest today with this curated day itinerary.

Riomaggiore is brimming with adventures.

To truly experience Lucca, make sure to drop by Riomaggiore. This underrated sightseeing destination is a must-visit for anyone seeking a unique vacation experience. Another sight you shouldn’t miss is Manarola Overlook Viewpoint, one of the village’s best highlights.

Next, check out Cinque Terre National Park, one of the most well-known places to see in Lucca. This national park is a favorite among locals and travelers alike. Enjoy some downtime and refreshments before continuing to your next stop, Saint Andrew's Church. Wander around and soak in the stunning atmosphere this church offers.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Lucca.

Lucca is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Lucca.

Have a fantastic dining experience at Osteria Nova, a highly recommended choice for tonight's dinner. If you're looking to mix things up, La Bottega di Anna e Leo offers an enticing alternative with its varied menu. Additionally, Ristorante Per 21 is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Lucca.

Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, La Tana Del Boia stands out as an excellent choice for a post-dinner cocktail. Alternatively, Vinarkia Della Pavona - Cocktail Bar offers an ideal atmosphere to enjoy the pleasures of the night. Magellano is also a great option that provides a perfect setting for a relaxing evening.

Savor another day of unforgettable experiences in Italy!

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Day 6

Day 6

  • Lucca
  • San Gimignano
  • More

Drive 185 km, 2 hours 46 min

  • Siena Cathedral
  • Pinacoteca Nazionale
  • piazza del Campo
  • Tower of Mangia
  • Parco della Rocca
  • Piazza del Duomo, San Gimignano
  • More

Your itinerary for day 6 of your road trip in Italy includes 2 stops and features some of the highlights of Siena and San Gimignano. At the end of the day, enjoy the comforts of a top-rated hotel in San Gimignano, where you'll spend 1 night.

Enjoy all that Siena Cathedral has to offer. This is a locally renowned church you should not miss. Another must-see is Pinacoteca Nazionale, an intriguing art gallery in Lucca.

When you’re ready for the next sight, head to Piazza Del Campo. From there, take a leisurely stroll to Tower Of Mangia, another of the city’s frequently visited attractions. We recommend continuing your self-guided tour at Parco Della Rocca, an enchanting place of interest in the city. If time allows, add Piazza Del Duomo to your itinerary. This worthwhile public square offers the perfect finishing touch to your day in Lucca.

When you’re done exploring for the day, you’ll drive to your hotel in San Gimignano. Check in and relax before you head out to tour the village.

After a day of adventure, treat yourself to an exquisite dinner at one of San Gimignano's best restaurants.

Raise your glass to another unforgettable day in Italy!

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Day 7

Day 7

  • San Gimignano
  • Rome
  • More

Drive 281 km, 4 hours 9 min

  • Castel Sant'Angelo
  • Piazza Navona
  • Pantheon
  • Trevi Fountain
  • Piazza di Spagna
  • Basilica di Santa Maria Maggiore
  • More

On day 7 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, including Rome. When you’re not sightseeing, take time to relax at your chosen hotel in Rome, where you’ll be staying for 2 nights.

Castel Sant'angelo leaves a lasting impression. This castle is one of the most impressive places to visit in San Gimignano. Next, head to Piazza Navona, an iconic public square, known for its grand features.

In between the sights, don’t hesitate to take small detours to explore local stores and eateries. When you’re ready to continue your adventure, head to Pantheon. This heritage-rich monument is a highly recommended experience. Nearby, you'll also find Trevi Fountain and Piazza Di Spagna. Visit these for an interesting touch to your journey. Finish the day with a visit to Basilica Di Santa Maria Maggiore, a culturally significant church in San Gimignano.

At the end of the day, you will drive to Rome, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Rome, it's often a good idea to reserve a table in advance.

Enjoy a lovely dining experience at La Bottega Roma, a popular restaurant in Rome. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Rome at Pasta In Corso, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated Trattoria Vecchia Roma. It’s yet another ideal choice to enhance your time in Rome tonight.

After enjoying a fulfilling meal, continue your evening at La Botticella Of Poggi Giovanni, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, Almalu Trastevere offers a welcoming atmosphere for easing into the nightlife. Similarly, Bar Viminale Di Pepi Maurilio provides an excellent environment for a relaxed and enjoyable evening.

Head back to your accommodation in Rome and get some rest to prepare for another magical day of your road trip in Italy.

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Day 8

Day 8

  • Rome
  • More

Drive 16 km, 1 hour 15 min

  • St Peter's Basilica
  • Colosseum
  • Roman Forum
  • Capitoline Hill
  • Altare della Patria
  • Archbasilica of St. John Lateran
  • More

On day 8 of your road trip, you’ll start and end your day in Rome, where you still have 1 night left. You'll spend part of the day exploring places of interest outside the immediate city, including Vatican City and Rome.

Whatever your travel style is, St. Peter's Basilica is an essential stop in Rome. This globally renowned major basilica provides an insightful glimpse into the city's identity. Next, discover Colosseum, a breathtaking archeological site, promising a delightful encounter.

Continue your sightseeing with a visit to Roman Forum, a timeless archeological site. When you’re done, don’t forget to make a stop at the interesting Capitoline Hill. Not far away from the public square, you will find the picture-perfect Archbasilica Of St. John Lateran, perfect for a quick visit. Round off your day at Altare Della Patria, another gem in Rome with historic features to discover.

When you’re done exploring for the day, you’ll return to Rome and your accommodation.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Rome. Enjoy a relaxing evening as you savor delicious local cuisine.

Savor the flavors at RomAntica, a top pick for dinner tonight. Alternatively, Coso Ristorante beckons with its unique menu offerings. Also, consider DEROMA - Farine Romane. With its consistent customer satisfaction, it’s an excellent option for dining in Rome tonight.

Cap off your dinner by heading to Sant' Eustachio Caffè, ideal for a leisurely evening with a drink in hand. Yellowsquare Rome is another bar that offers an enjoyable setting. Similarly, Caffè Portofino is also a popular place to go on a night out, perfect for relaxing and socializing.

As the sun sets, rest up and recharge for the next leg of your road trip in Italy.

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Day 9

Day 9

  • Rome
  • Venice
  • More

Drive 608 km, 7 hours 21 min

  • Piazza del Comune
  • Portico of Monte Frumentario
  • Basilica of San Francesco d'Assisi
  • More

On day 9 of your road trip in Italy, your travel plans include 1 stop at the most scenic, wondrous, and interesting places in the region. Santa Maria degli Angeli are on today's agenda. In the evening, you’ll end up in Venice, where you will stay for 1 night.

Piazza Del Comune is must-visit public square and a great option for a daytime tour of the area. Continue your journey to Portico Of Monte Frumentario, a frequently visited historical landmark, located just a leisurely stroll away. Next, head to Basilica Of San Francesco D'assisi, a breathtaking church, also available for your discovery today.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Venice. Venice offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

Venice is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Venice.

Treat yourself to a wonderful meal at Osteria Alla Staffa, a top-rated dining spot in Venice. If you're in the mood for something new, try Bistrot de Venise, another premier location with a delectable menu. You might also want to book a table at Corte Sconta. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Venice.

Extend your evening after a delightful meal by visiting Dolce Vita Venezia, which offers the perfect atmosphere for a night out. Moreover, Tarnowska's American Bar is another popular option for a drink or two. Likewise, Bar All'angolo also provides a great ambiance for reminiscing about the day and raising a toast to your vacation.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in Italy.

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Day 10

Day 10

  • Venice - Departure day
  • More
  • Palazzo Contarini del Bovolo
  • More

Day 10 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Venice before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, begin at Palazzo Contarini Del Bovolo. This interesting palace is a hotspot among locals.

Take some time to indulge in shopping at Venice’s popular marketplace, Rialto Market. Look for keepsakes or souvenirs to remind you of your trip.

Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Venice.

If you're eager to try something different, consider Trattoria Al Gazzettino, another top spot with a tantalizing menu.

You’ll then say farewell to Venice. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!

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Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

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Your trip is protected, personalized, and priced right. No surprises, no stress.

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