10-Day Italy Self-Drive Road Trip With Itinerary from Venice to Florence, Lucca, San Gimignano, and Rome

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Escape the ordinary with this exciting 10-day road trip through Italy. Explore the diverse landscapes, lively cities, and beyond. Pack your bags, hit the road, and prepare for an unforgettable journey!

This perfectly planned road trip itinerary in Italy takes you through some of the best places to see in the country. You will spend 3 nights in Venice, 1 night in Florence, 2 nights in Lucca, 1 night in San Gimignano, and 2 nights in Rome. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Venice, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Trevi Fountain and Colosseum are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Pantheon, learn more about the unique Piazza Navona, and immerse yourself in the vibrant atmosphere of Piazza San Marco.

As you hit the open road and drive through Venice, Florence, Pisa, Lucca, Levanto, Vernazza, Corniglia, Manarola, Siena, San Gimignano, Rome, and Santa Maria degli Angeli, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.

Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!

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Itinerary summary

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Days
Destination
Attractions
Overnight
Day
City & Overnight
Attractions
Teatro La Fenice
Piazza San MarcoSt Mark's BasilicaDoge's PalaceBridge of SighsCannaregio
Palazzo VecchioCathedral of Santa Maria del FioreBrunelleschi's domepiazza della Signoria
Basilica of Santa Croce in FlorencePisa CathedralPiazza del Duomo, PisaLeaning Tower of PisaPiazza dell'Anfiteatro
Punta MescoSentiero Monterosso - VernazzaRuins of Doria TowerCinque Terre National Park
Fortezza Mediceapiazza del CampoSiena CathedralPorta San GiovanniPiazza del Duomo, San Gimignano

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Day 1

Day 1

  • Venice - Arrival day
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  • Teatro La Fenice
  • More

Your road trip adventure in Italy begins as soon as you reach Venice and pick up your car. You’ll stay in Venice for 2 nights and explore the best things to see and do, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.

Venice is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Teatro La Fenice or taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

As afternoon approaches, head to your chosen hotel in Venice. Check-in typically starts around 2 to 4 PM at hotels in Italy. We recommend staying at a hotel in a central location for easy access to the best attractions, restaurants, and bars in the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Venice, it's often a good idea to reserve a table in advance.

Treat yourself to a delightful dinner at Bauer Hotel, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try L'Osteria Le Guglie? It's another excellent option with a diverse menu. Consider reserving a table at Corner Pub as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Venice.

Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, Al Parlamento stands out as an excellent choice for a post-dinner cocktail. Alternatively, The Caffe Rosso offers an ideal atmosphere to enjoy the pleasures of the night. Adagio is also a great option that provides a perfect setting for a relaxing evening.

Raise a toast to the start of your 10-day road trip in Italy!

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Day 2

Day 2

  • Venice
  • More

Drive 2 km, 29 min

  • Piazza San Marco
  • St Mark's Basilica
  • Doge's Palace
  • Bridge of Sighs
  • Cannaregio
  • More

Day 2 offers a multitude of experiences. You will stay in Venice for 1 night more, offering you enough time to explore at a relaxed pace.

Cannaregio is one of the highlights of today. Take your time exploring this iconic neighborhood in Venice, which offers a perfect blend of history and culture. Plus, it's close to many other must-see landmarks.

Prepare for a day full of family-friendly attractions, romantic experiences, and scenic views. When you’re ready, kick off your sightseeing adventure at Piazza San Marco. This timeless public square is a must-visit for anyone seeking a unique vacation experience. Another sight you shouldn’t miss is St Mark's Basilica, one of the city’s most promising highlights.

Next, check out Doge's Palace, one of the most notable places to see in Venice. This palace is a favorite among locals and travelers alike. Enjoy some downtime and refreshments before continuing to your next stop, Bridge Of Sighs. Wander around and soak in the enchanting atmosphere this monument offers.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

As you explore more of Venice, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Enjoy a delicious meal at Generator Venice, a top-rated dining destination in Venice. If you're in the mood to try something new, consider Nevodi, another top spot with a mouthwatering menu. You might also want to secure a reservation at Ristorante La Piazza. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Venice this evening.

Following your dinner, dive into the local bar culture at Il Mercante. Enjoy this evening's relaxed ambiance with delightful drinks. Alternatively, go to The Irish Pub Venezia, the perfect place for those looking to experience the best of the nightlife. Similarly, Ai Stagneri provides excellent drinks and a great atmosphere, ensuring a memorable night out.

Say good night to Venice and look forward to another great day of your road trip in Italy!

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Day 3

Day 3

  • Venice
  • Florence
  • More

Drive 262 km, 3 hours 16 min

  • Palazzo Vecchio
  • Cathedral of Santa Maria del Fiore
  • Brunelleschi's dome
  • piazza della Signoria
  • More

Experience an unparalleled adventure on day 3 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 vibrant destinations - Florence. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Florence. You will spend 1 night here for some well-deserved relaxation.

Florence’s wonders await as you prepare for another journey on the road, leaving the breathtaking surroundings of Venice behind. This drive usually takes around 2 hours 52 min. Florence welcomes you with a multitude of unique vacation experiences.

Begin your journey at Palazzo Vecchio and explore the grand features. Next, make your way to Cathedral Of Santa Maria Del Fiore, another highlight in the city. When you’re done exploring the church, continue to Brunelleschi's Dome, a visually striking monument. Nearby, you will also find Piazza Della Signoria. This famous public square is a top place to see in the area.

When you’re done exploring for the day, you’ll drive to your hotel in Florence. Check in and spend some time relaxing before you head out to tour the city.

As you explore more of Florence, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Dine in style at Ristorante Oliviero 1962, a top recommendation for dinner tonight. Or, for a change of pace, Di Poneta Novoli boasts a menu that's sure to impress. Also, be sure to check out Caffe San Firenze. Known as a local hotspot, it’s a great choice for tonight in Florence.

Following your dinner, dive into the local bar culture at Manifattura. Enjoy this evening's relaxed ambiance with delightful drinks. Alternatively, go to Se·sto On Arno Rooftop Bar, the perfect place for those looking to experience the best of the nightlife. Similarly, Il Vinile provides excellent drinks and a great atmosphere, ensuring a memorable night out.

Say good night to Florence and look forward to another great day of your road trip in Italy!

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Day 4

Day 4

  • Florence
  • Pisa
  • Lucca
  • More

Drive 111 km, 2 hours 11 min

  • Basilica of Santa Croce in Florence
  • Pisa Cathedral
  • Piazza del Duomo, Pisa
  • Leaning Tower of Pisa
  • Piazza dell'Anfiteatro
  • More

On day 4 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Florence, Pisa, and Lucca. In the evening, you’ll end up in Lucca, where you will stay for 2 nights.

Get ready for a day filled with family-friendly attractions, photo-friendly spots, and historic treasures in the charming city of Florence. Your adventure starts at Basilica Of Santa Croce In Florence, a popular local hot spot.

Set your GPS to Pisa and hit the road. Expect a journey of approximately 1 hour 19 min without stops. Soak in the beautiful landscapes as you drive and look forward to exploring your next destination. Pisa beckons with new experiences!

One of our top recommendations for your sightseeing is Pisa Cathedral. Spend some time admiring the historic features of the church before you continue to your next stop. Then, head to Piazza Del Duomo, Pisa. This globally renowned public square is a traveler-favorite in the city. Not far away, you’ll also find Leaning Tower Of Pisa. Feed your curiosity by learning something new about the monument.

When you’re ready to jump back into the car and say goodbye to Pisa, you’ll hit the road in the direction of Lucca. This drive usually takes around 32 min. When you arrive, enjoy some sightseeing.

Your self-guided tour starts at Piazza Dell'anfiteatro, an interesting public square that is sure to impress. Take in the surroundings and enjoy the freedom of exploring before you continue your journey.

After soaking up all the sights of today's itinerary, you'll be ready to hit the road in the direction of your accommodation in Lucca. Lucca offers plenty of top-rated hotels and other places to stay on any travel budget. Take some time to relax before you head out to explore.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Lucca. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Don’t miss out on dining at Gli Orti di Via Elisa, a top-rated dining destination in Lucca. If you're in the mood to try something new, consider Bar Caffè Ristretto, another top spot with a mouthwatering menu. You might also want to secure a reservation at Ristorante Schiaffino. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Lucca this evening.

After enjoying a fulfilling meal, continue your evening at Lebowski - Cocktail Bar, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, Blend offers a welcoming atmosphere for easing into the nightlife. Similarly, Franklin'33 provides an excellent environment for a relaxed and enjoyable evening.

As the sun sets on another day of adventure, rest up and recharge for the next leg of your road trip in Italy.

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Day 5

Day 5

  • Lucca
  • Levanto
  • Vernazza
  • Corniglia
  • More

Drive 243 km, 4 hours 39 min

  • Punta Mesco
  • Sentiero Monterosso - Vernazza
  • Ruins of Doria Tower
  • Cinque Terre National Park
  • More

On day 5 of your road trip, you’ll start and end your day in Lucca, where you'll stay for 1 night more.

When you’re ready to jump back into the car and say goodbye to Lucca, you’ll hit the road in the direction of Levanto. This drive usually takes around 1 hour 40 min. When you arrive, enjoy some sightseeing.

Begin your journey at Punta Mesco and explore the eye-catching features.

As you’ve unraveled the marvels of Levanto, it’s time to gear up for the next part of your road trip adventure. Under favorable conditions, your drive to Vernazza may take around 44 min. Upon your arrival in Vernazza, you’ll be greeted with the opportunity to do some sightseeing and exploring.

One of our top recommendations for your sightseeing is Sentiero Monterosso - Vernazza. Spend some time admiring the mesmerizing features of the hiking area before you continue to your next stop. Then, head to Ruins Of Doria Tower. This underrated monument is a traveler-favorite in the city.

Continue your road trip and head to your next destination, Corniglia. This car ride takes around 16 min.

Savor the rest of your day by heading to Cinque Terre National Park, a locally renowned national park that draws visitors from near and far.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Lucca.

As you explore more of Lucca, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Enjoy a lovely meal at Osteria Nova, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, La Bottega di Anna e Leo is another top choice with a popular menu. You could also check for a table at Ristorante Per 21. As an establishment that gains consistently high praises from customers, it’s an ideal choice in Lucca tonight.

Following your dinner, dive into the local bar culture at La Tana Del Boia. Enjoy this evening's relaxed ambiance with delightful drinks. Alternatively, go to Vinarkia Della Pavona - Cocktail Bar, the perfect place for those looking to experience the best of the nightlife. Similarly, Magellano provides excellent drinks and a great atmosphere, ensuring a memorable night out.

Get a good night's sleep and look forward to another great day on the road in Italy!

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Day 6

Day 6

  • Lucca
  • Siena
  • More

Drive 186 km, 2 hours 53 min

  • Fortezza Medicea
  • piazza del Campo
  • Siena Cathedral
  • Porta San Giovanni
  • Piazza del Duomo, San Gimignano
  • More

Dive into day 6 of your remarkable road trip in Italy. Today you will explore Siena and San Gimignano, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in San Gimignano. You’ll stay here for 1 night.

Continue your road trip and head to your next destination, Siena. This car ride takes around 1 hour 42 min.

Your self-guided tour starts at Fortezza Medicea (siena), a curiosity-inducing monument that is sure to impress. Take in the surroundings and enjoy the freedom of exploring before you continue your journey. Next, head to Piazza Del Campo and admire its romantic features. When you’re ready, continue to Siena Cathedral, a notable church beloved by locals and tourists alike.

When you’ve had your share of Siena, prepare for your next destination. Admire the views and listen to some good music as you drive in the direction of San Gimignano. Your travel time is around 42 min.

Begin your journey at Porta San Giovanni and explore the historic features. Next, make your way to Piazza Del Duomo, another highlight in the city.

At the end of the day, you will drive to San Gimignano, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a day of adventure, treat yourself to an exquisite dinner at one of San Gimignano's best restaurants.

Take some time to reflect on your day and savor another beautiful night in Italy.

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Day 7

Day 7

  • Rome
  • More

Drive 276 km, 4 hours 12 min

  • Colosseum
  • Roman Forum
  • Trevi Fountain
  • Piazza Navona
  • Pantheon
  • More

Embark on another extraordinary experience on day 7 of your road trip in Italy. Today, you will make 1 stop and experience some of the highlights of Rome. At the end of the day, you will enjoy the comforts of a top-rated hotel in Rome, which will be your home away from home for 2 nights.

Immerse yourself in Rome’s rich culture with today's sightseeing itinerary.

As you’ve unraveled the marvels of San Gimignano, it’s time to gear up for the next part of your road trip adventure. Under favorable conditions, your drive to Rome may take around 3 hours 16 min. Upon your arrival in Rome, you’ll be greeted with the opportunity to do some sightseeing and exploring.

Make your way to Colosseum, a globally renowned archeological site that draws attention for its picture-perfect features. Spend some time soaking in the atmosphere before continuing to Roman Forum, a picture-perfect archeological site that stands out in the city. Next, visit Trevi Fountain, a world-famous monument that offers a unique experience. Be sure to also explore Piazza Navona, a nearby public square, which is highly recommended by other travelers. End your self-guided tour at Pantheon, a culturally significant monument and the perfect final attraction in Rome.

When you’re done exploring for the day, you’ll drive to your hotel in Rome. Check in and spend some time relaxing before you head out to tour the city.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Rome. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Enjoy a lovely dining experience at La Bottega Roma, a popular restaurant in Rome. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Rome at Pasta In Corso, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated Trattoria Vecchia Roma. It’s yet another ideal choice to enhance your time in Rome tonight.

Keep the evening going at La Botticella Of Poggi Giovanni, a great choice for enjoying the after-dinner hours with a drink. You could also go to Almalu Trastevere, which offers a similarly pleasant setting and great drinks. Another option is Bar Viminale Di Pepi Maurilio, which provides an inviting environment for unwinding after a busy day out.

Relax and recharge in preparation for another adventurous day in Italy!

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Day 8

Day 8

  • Rome
  • More

Drive 11 km, 44 min

  • Piazza di Spagna
  • Trastevere
  • Monti
  • Via del Corso
  • More

Day 8 of your road trip across Italy promises a magnificent time exploring Vatican City. You have 1 night left in Rome. Take the opportunity to experience more of the best attractions and activities in the city.

Don’t miss Trastevere in Vatican City today, a must-see neighborhood that offers a glimpse into the city’s vibrant character. Take your time exploring its best features, and enjoy the convenience of nearby top-rated landmarks.

A blend of fun adventures, romantic experiences, and scenic views await you in Rome on today’s itinerary. First up is the timeless public square, Piazza Di Spagna. It's a standout spot that offers a memorable visit.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

Indulge in a memorable dining experience at one of Rome's most popular restaurants, and connect with friendly locals for an authentic adventure.

Make sure to reserve a table at RomAntica, an iconic dining spot in Rome. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Coso Ristorante, a popular restaurant in Rome. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of DEROMA - Farine Romane, a hidden gem nestled in Rome. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Continue your evening by exploring the vibrant nightlife scene at Sant' Eustachio Caffè, a prime destination for a thrilling night out. Also, don’t forget to check out Yellowsquare Rome, a bar that offers unique local touches. Likewise, Caffè Portofino provides an excellent alternative for a fun evening.

Celebrate another amazing day of your road trip adventure in Italy!

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Day 9

Day 9

  • Rome
  • Assisi
  • Venice
  • More

Drive 611 km, 7 hours 27 min

  • Piazza del Comune
  • Portico of Monte Frumentario
  • Porta San Giacomo
  • More

On day 9 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, Santa Maria degli Angeli. When you’re not sightseeing, take time to relax at your selected hotel in Venice, where you’ll be staying for 1 night.

Today's adventure in Santa Maria degli Angeli promises more breathtaking discoveries and enriching experiences!

Embrace the thrill of the open road as you wave goodbye to Rome and set your GPS to Santa Maria degli Angeli. While on the road, immerse yourself in your favorite road trip tunes or sample the sounds from a local radio station. This car ride usually takes around 2 hours 28 min. Upon reaching Santa Maria degli Angeli, unwind, observe, and explore. The best things to do, see, and eat are waiting for you.

Spend your afternoon discovering Piazza Del Comune, a curiosity-inducing public square known for its romantic features. After taking in the atmosphere, continue to Portico Of Monte Frumentario, an underrated historical landmark that is a must-see for anyone visiting the region.

After soaking up all the sights of today's itinerary, you'll be ready to hit the road in the direction of your accommodation in Venice. Venice offers plenty of top-rated hotels and other places to stay on any travel budget. Take some time to relax before you head out to explore.

Indulge in a memorable dining experience at one of Venice's most popular restaurants, and connect with friendly locals for an authentic adventure.

Enjoy a lovely meal at Osteria Alla Staffa, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Bistrot de Venise is another top choice with a popular menu. You could also check for a table at Corte Sconta. As an establishment that gains consistently high praises from customers, it’s an ideal choice in Venice tonight.

Explore the vibrant nightlife at Dolce Vita Venezia after your meal, a hub for lively evenings and memorable moments. Or, head to Tarnowska's American Bar for a great selection of flavorful drinks and a charming setting. Furthermore, Bar All'angolo is perfect for those looking to extend their night with a touch of local flavor.

Celebrate another amazing day of your road trip adventure in Italy!

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Day 10

Day 10

  • Venice - Departure day
  • More
  • Rialto Bridge
  • More

Day 10 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Venice before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

Explore local shops for souvenirs to remember your trip or find unique gifts for loved ones. Discover boutiques offering an array of stylish fashion choices. For those seeking luxury items, check out the area’s high-end stores.

Today's adventure in Venice promises more breathtaking discoveries and enriching experiences! Begin at Rialto Bridge. This romantic historical landmark is a highlight of any visit in the city.

Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Venice.

You’ll then say farewell to Venice. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!

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