10-Day Italy Self-Drive Road Trip With Itinerary from Venice to Florence, Lucca, San Gimignano, and Rome

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Bridge Rialto on Grand canal famous landmark panoramic view Venice Italy.
10-Day Italy Self-Drive Road Trip With Itinerary from Venice to Florence, Lucca, San Gimignano, and Rome
10-Day Italy Self-Drive Road Trip With Itinerary from Venice to Florence, Lucca, San Gimignano, and Rome
10-Day Italy Self-Drive Road Trip With Itinerary from Venice to Florence, Lucca, San Gimignano, and Rome
10-Day Italy Self-Drive Road Trip With Itinerary from Venice to Florence, Lucca, San Gimignano, and Rome
10-Day Italy Self-Drive Road Trip With Itinerary from Venice to Florence, Lucca, San Gimignano, and Rome
10-Day Italy Self-Drive Road Trip With Itinerary from Venice to Florence, Lucca, San Gimignano, and Rome
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Explore the best of Italy on a remarkable 10-day road trip! Combine exploration with relaxation on a self-drive tour featuring Venice, Murano, Florence, Pisa, Lucca, Riomaggiore, Manarola, Corniglia, Levanto, Siena, San Gimignano, Rome, and Santa Maria degli Angeli.

This perfectly planned road trip itinerary takes you through some of the best places to see in Italy. You will spend 3 nights in Venice, 1 night in Florence, 2 nights in Lucca, 1 night in San Gimignano, and 2 nights in Rome. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Venice, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Trevi Fountain and Colosseum are just a couple of the bucket-list attractions that await your discovery.

As you hit the open road and drive through Venice, Murano, Florence, Pisa, Lucca, Riomaggiore, Manarola, Corniglia, Levanto, Siena, San Gimignano, Rome, and Santa Maria degli Angeli, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.

Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!

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Day1

Day 1

  • Venice - Arrival day
  • More
  • Rialto Bridge
  • More

Say hello to Venice! Your exciting road trip through Italy is just about to start. Navigating the top places to see in the region is a breeze with a car. The rental vehicle of your choice will be ready for pickup upon your arrival in the city. You will stay in Venice for 2 nights before you continue your adventure!

Venice is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Rialto Bridge. Taking a stroll in the city center is a great alternative. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

As afternoon approaches, head to your chosen hotel in Venice. Check-in typically starts around 2 to 4 PM at hotels in Italy. We recommend staying at a central location for easy access to key areas in the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Venice, it's often a good idea to reserve a table in advance.

Dine in style at Bauer Hotel, a top recommendation for dinner tonight. Or, for a change of pace, L'Osteria Le Guglie boasts a menu that's sure to impress. Also, be sure to check out Corner Pub. Known as a local hotspot, it’s a great choice for tonight in Venice.

Round off your dining experience by visiting Al Parlamento, a prime location for a drink. Alternatively, explore the distinctive characteristics of The Caffe Rosso, a bar catering to every mood and preference. Adagio likewise offers a unique atmosphere, perfect for a memorable night out.

Raise a toast to the start of your 10-day road trip in Italy!

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Day2

Day 2

  • Venice
  • Murano
  • More

Drive 14 km, 34 min

  • Piazza San Marco
  • St Mark's Campanile
  • St Mark's Basilica
  • Doge's Palace
  • Bridge of Sighs
  • Murano
  • More

Wake up to day 2 of your road trip in Italy. On this day, you’ll embark on an exciting expedition discovering the enchanting sights and activities of Venice and Murano. With 1 night to stay in Venice, we encourage you to seize the day and discover the unexplored beauty of the city’s surroundings!

Whatever your travel style is, Piazza San Marco is an essential stop in Venice. This timeless public square provides an insightful glimpse into the city's identity. Next, discover St Mark's Campanile, an UNESCO world heritage-designated monument, promising a delightful encounter.

Continue your sightseeing with a visit to St Mark's Basilica, a notable church. When you’re done, don’t forget to make a stop at the locally renowned Doge's Palace. Round off your day at Bridge Of Sighs, another gem in Venice with UNESCO world heritage-listed features to discover.

Murano’s wonders await as you prepare for another journey on the road, leaving the breathtaking surroundings of Venice behind. This drive usually takes around 1 min. Murano welcomes you with a multitude of unique vacation experiences.

One of our top recommendations for your sightseeing is Murano. Spend some time admiring the romantic features of the handicraft store before you continue to your next stop.

When you’re done exploring for the day, you’ll return to Venice and your accommodation.

Indulge in a memorable dining experience at one of Venice's most popular restaurants, and connect with friendly locals for a true cultural experience.

Treat yourself to a delightful dinner at Generator Venice, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Nevodi? It's another excellent option with a diverse menu. Consider reserving a table at Ristorante La Piazza as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Venice.

Extend your evening after a delightful meal by visiting Il Mercante, which offers the perfect atmosphere for a night out. Moreover, The Irish Pub Venezia is another popular option for a drink or two. Likewise, Ai Stagneri also provides a great ambiance for reminiscing about the day and raising a toast to your vacation.

Raise your glass to another unforgettable day in Italy!

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Day3

Day 3

  • Venice
  • Florence
  • More

Drive 263 km, 3 hours 20 min

  • Ponte Vecchio
  • Uffizi Gallery
  • Basilica of Santa Croce in Florence
  • Hercules and Cacus
  • piazza della Signoria
  • More

On day 3 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, including Florence. When you’re not sightseeing, take time to relax at your chosen hotel in Florence, where you’ll be staying for 1 night.

Embrace the thrill of the open road as you wave goodbye to Venice and set your GPS to Florence. While on the road, immerse yourself in your favorite road trip tunes or sample the sounds from a local radio station. This car ride usually takes around 2 hours 52 min. Upon reaching Florence, unwind, observe, and explore. The best things to do, see, and eat are waiting for you.

Set out on a self-guided sightseeing tour at Ponte Vecchio and explore the romantic features. Next, make your way to Uffizi Gallery, another highlight in Florence. When you’re done exploring the art gallery, continue to Basilica Of Santa Croce In Florence, a culturally significant church.

Nearby, you will also find Hercules And Cacus. This beloved sculpture is a top place to see in the area. Lastly, head to Piazza Della Signoria, a history-steeped public square that is perfect for some final exploring in the city.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Florence. Florence offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Florence. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Enjoy a lovely meal at Ristorante Oliviero 1962, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Di Poneta Novoli is another top choice with a popular menu. You could also check for a table at Caffe San Firenze. As an establishment that consistently gains high praises from customers, it’s an ideal choice in Florence tonight.

If you’re not ready to end the night just yet, Manifattura offers a perfect venue to relax and savor a drink. Similarly, Se·sto On Arno Rooftop Bar is well-suited for those looking to unwind in a social setting. Il Vinile is another excellent spot to enjoy a nightcap after a delightful meal.

Relax and recharge in preparation for another adventurous day in Italy!

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Day4

Day 4

  • Florence
  • Pisa
  • Lucca
  • More

Drive 109 km, 2 hours 13 min

  • Cathedral of Santa Maria del Fiore
  • Galleria dell'Accademia
  • Piazza del Duomo, Pisa
  • Leaning Tower of Pisa
  • Walls of Lucca
  • More

Experience an unparalleled adventure on day 4 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 3 places, which are Florence, Pisa, and Lucca. At the end of the day, you will retreat to the hotel of your choice in Lucca, where will spend 2 nights.

Let Cathedral Of Santa Maria Del Fiore set the tone for the day. Spend some time admiring this culturally significant church before continuing your journey. Galleria Dell'accademia is your next stop. This captivating art gallery is one of the best-rated sights in Florence.

When you’ve had your share of Florence, prepare for your next destination. Admire the views and listen to some good music as you drive in the direction of Pisa. Your travel time is around 1 hour 19 min.

One of our top recommendations for your sightseeing is Piazza Del Duomo, Pisa. Spend some time admiring the picture-perfect features of the public square before you continue to your next stop. Then, head to Leaning Tower Of Pisa. This globally renowned monument is a traveler-favorite in the city.

When you’ve had your share of Pisa, prepare for your next destination. Admire the views and listen to some good music as you drive in the direction of Lucca. Your travel time is around 31 min.

Our first attraction recommendation in Lucca is Mura Di Lucca, a locally appreciated historical landmark that draws attention for its romantic features.

When you’re done exploring for the day, you’ll drive to your hotel in Lucca. Check in and relax before you head out to tour the city.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Lucca. Enjoy a relaxing evening as you savor delicious local cuisine.

Treat yourself to a wonderful meal at Gli Orti di Via Elisa, a top-rated dining spot in Lucca. If you're in the mood for something new, try Bar Caffè Ristretto, another premier location with a delectable menu. You might also want to book a table at Ristorante Schiaffino. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Lucca.

After savoring a delicious meal, step into the vibrant nightlife at Lebowski - Cocktail Bar, where the evening is just getting started. In the same way, Blend offers a unique charm perfect for experiencing the local bar scene in Lucca. Franklin'33 is another top-recommended bar that is sure to get you into the mood for some dancing and celebrating.

Savor another day of unforgettable experiences in Italy!

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Day5

Day 5

  • Lucca
  • Riomaggiore
  • Manarola
  • Corniglia
  • More

Drive 226 km, 4 hours 24 min

  • Riomaggiore
  • Manarola Overlook Viewpoint
  • Cinque Terre National Park
  • More

On day 5 of your road trip, you’ll start and end your day in Lucca, where you still have 1 night left. You'll spend part of the day exploring places of interest outside the immediate city, including Riomaggiore, Manarola, Corniglia, and Levanto.

As you explore Riomaggiore’s charming streets, take in the lively atmosphere and get to know the character of the village.

Fasten your seatbelt and make your way to your next stop — Riomaggiore, home to many well-known sights in the region. Keep in mind that your travel time from Lucca to Riomaggiore may take around 1 hour 22 min without traffic disruptions. Upon arrival in Riomaggiore, we highly recommend checking out some of the top attractions.

Savor the day by heading to Riomaggiore, a frequently visited sightseeing destination that draws visitors from near and far.

Once you're ready to continue your road trip, it's time to buckle up and drive, eagerly anticipating your arrival in Corniglia. This drive usually takes around 15 min, without any stops or traffic disruptions.

Our first attraction recommendation in Manarola is Manarola Overlook Viewpoint, a locally appreciated observation deck that draws attention for its romantic features.

Fasten your seatbelt and make your way to your next stop — Corniglia, home to many well-known sights in the region. Keep in mind that your travel time from Manarola to Corniglia may take around 15 min without traffic disruptions. Upon arrival in Corniglia, we highly recommend checking out some of the top attractions.

For a more meaningful self-guided tour of the village's best attractions, visit Cinque Terre National Park, a locally renowned national park that is sure to impress. Take in the surroundings and enjoy the freedom of exploring at your own pace before you continue your journey.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Lucca.

Lucca is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Lucca.

Enjoy a delicious meal at Osteria Nova, a top-rated dining destination in Lucca. If you're in the mood to try something new, consider La Bottega di Anna e Leo, another top spot with a mouthwatering menu. You might also want to secure a reservation at Ristorante Per 21. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Lucca this evening.

Unwind after your meal by stepping into La Tana Del Boia. This venue is celebrated for its extensive drink selections and cozy vibes. Alternatively, Vinarkia Della Pavona - Cocktail Bar offers a dynamic and energetic atmosphere for a glass or two. Don’t overlook Magellano, another top-rated bar in the area.

Say good night to Lucca and look forward to another great day of your road trip in Italy!

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Day6

Day 6

  • Lucca
  • Siena
  • San Gimignano
  • More

Drive 185 km, 2 hours 46 min

  • Siena Cathedral
  • Pinacoteca Nazionale
  • piazza del Campo
  • Tower of Mangia
  • Parco della Rocca
  • Piazza del Duomo, San Gimignano
  • More

Your itinerary for day 6 of your road trip in Italy includes 2 stops and features some of the highlights of Siena and San Gimignano. At the end of the day, enjoy the comforts of a top-rated hotel in San Gimignano, where you'll spend 1 night.

Fasten your seatbelt and make your way to your next stop — Siena, home to many well-known sights in the region. Keep in mind that your travel time from Lucca to Siena may take around 1 hour 44 min without traffic disruptions. Upon arrival in Siena, we highly recommend checking out some of the top attractions.

Our first attraction recommendation in Siena is Siena Cathedral, an interesting church that draws attention for its majestic features. Spend some time soaking in the atmosphere before continuing to Pinacoteca Nazionale, a standout art gallery that stands out in the city.

Time flies when you're having fun! But don't forget to stop for a bit to eat and drink between your adventures. When you're rested and recharged, head to Piazza Del Campo, a top-rated public square that offers a unique experience. Be sure to also explore Tower Of Mangia, a nearby monument, highly recommended by other travelers.

Once you're ready to continue your road trip, it's time to buckle up and drive, eagerly anticipating your arrival in San Gimignano. This drive usually takes around 47 min, without any stops or traffic disruptions.

For a more meaningful self-guided tour of the city's best attractions, visit Parco Della Rocca, a locally appreciated park that is sure to impress. Take in the surroundings and enjoy the freedom of exploring at your own pace before you continue your journey. Next, head to Piazza Del Duomo and admire its UNESCO world heritage-listed features.

At the end of the day, you will drive to San Gimignano, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a day of adventure, treat yourself to an exquisite dinner at one of San Gimignano's best restaurants.

As the sun sets, rest up and recharge for the next leg of your road trip in Italy.

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Day7

Day 7

  • San Gimignano
  • Rome
  • More

Drive 281 km, 4 hours 9 min

  • Castel Sant'Angelo
  • Piazza Navona
  • Pantheon
  • Trevi Fountain
  • Piazza di Spagna
  • Basilica di Santa Maria Maggiore
  • More

Dive into day 7 of your remarkable road trip in Italy. Today you'll explore 1 destination, including Rome. At the end of the day, you’ll unwind at one of the finest accommodations in Rome, where you'll spend 2 nights.

Continue your road trip and head to your next destination, Rome. This car ride takes around 3 hours 8 min.

Spend your afternoon discovering Castel Sant'angelo, an astonishing castle known for its history-steeped features. Next, continue your sightseeing at Piazza Navona, a globally renowned public square.

If you're starting to feel hungry, this is a great time for a break at a nearby restaurant or cafe. When you're ready for more, stop by Pantheon and uncover the details of this heritage-rich monument. Make sure to also explore Trevi Fountain, an iconic monument. For your last stop, consider Piazza Di Spagna, a history-steeped public square that many travelers find worth the detour.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Rome. Rome offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

Rome is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Rome.

Make sure to reserve a table at La Bottega Roma, an iconic dining spot in Rome. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Pasta In Corso, a popular restaurant in Rome. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Trattoria Vecchia Roma, a hidden gem nestled in Rome. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Continue the enjoyment post-dinner at La Botticella Of Poggi Giovanni, a cherished local gathering spot renowned for its welcoming atmosphere. Similarly, Almalu Trastevere offers a vibrant space for indulging in well-crafted drinks and engaging conversation. You may also want to check out Bar Viminale Di Pepi Maurilio. This bar is a favorite among both locals and visitors looking for a delightful evening out filled with laughter and fun.

Say good night to Rome and look forward to another great day of your road trip in Italy!

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Day8

Day 8

  • Rome
  • Vatican City
  • More

Drive 16 km, 1 hour 15 min

  • St Peter's Basilica
  • Colosseum
  • Roman Forum
  • Capitoline Hill
  • Altare della Patria
  • Archbasilica of St. John Lateran
  • More

On day 8 of your road trip, you'll get the chance to experience Vatican City and Rome. At the end of the day, you'll drive back to Rome, where you still have 1 night left to stay.

Let Colosseum set the tone for the day. Spend some time admiring this picture-perfect archeological site before continuing your journey. Roman Forum is your next stop. This wondrous archeological site is one of the best-rated sights in Rome.

Consider grabbing some lunch or a light snack to keep your energy going. Beyond the above-mentioned attractions, today is also the perfect time to visit Capitoline Hill. This visually striking public square is a sight to behold. To round off your sightseeing experience, visit Altare Della Patria and Archbasilica Of St. John Lateran.

When you’re done exploring for the day, you’ll return to Rome and your accommodation.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Rome. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Enjoy a delicious meal at RomAntica, a highly-rated dining destination in Rome. If you're eager to try something different, consider Coso Ristorante, another top spot with a tantalizing menu. You might also want to secure a reservation at DEROMA - Farine Romane. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Rome this evening.

Let the evening flow smoothly from dinner to drinks at Sant' Eustachio Caffè, a top-rated bar in the area. For other recommendations, Yellowsquare Rome provides a perfect setting for rounding out your night with style and great drinks. Likewise, Caffè Portofino offers a memorable night with diverse drink options and excellent service.

Take some time to reflect on your day and savor another beautiful night in Italy.

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Day9

Day 9

  • Rome
  • Assisi
  • Venice
  • More

Drive 608 km, 7 hours 21 min

  • Piazza del Comune
  • Portico of Monte Frumentario
  • Basilica of San Francesco d'Assisi
  • More

On day 9 of your road trip in Italy, your travel plans include 1 stop at the most scenic, wondrous, and interesting places in the region. Santa Maria degli Angeli are on today's agenda. In the evening, you’ll end up in Venice, where you will stay for 1 night.

As you explore Santa Maria degli Angeli’s charming streets, take in the lively atmosphere and get to know the character of the town.

When you’ve had your share of Rome, prepare for your next destination. Admire the views and listen to some good music as you drive in the direction of Santa Maria degli Angeli. Your travel time is around 2 hours 28 min.

Piazza Del Comune is an up-and-coming public square we recommend visiting today. Discover its UNESCO world heritage-listed features before continuing your self-guided tour to Portico Of Monte Frumentario, a respected historical landmark that’s well-regarded in the area.

Next, stop by Basilica Of San Francesco D'assisi, a historic church.

When you’re done exploring for the day, you’ll drive to your hotel in Venice. Check in and relax before you head out to tour the city.

Indulge in a memorable dining experience at one of Venice's most popular restaurants, and connect with friendly locals for a true cultural experience.

Savor the flavors at Osteria Alla Staffa, a top pick for dinner tonight. Alternatively, Bistrot de Venise beckons with its unique menu offerings. Also, consider Corte Sconta. With its consistent customer satisfaction, it’s an excellent option for dining in Venice tonight.

Keep the evening going at Dolce Vita Venezia, a great choice for enjoying the after-dinner hours with a drink. You could also go to Tarnowska's American Bar, which offers a similarly pleasant setting and great drinks. Another option is Bar All'angolo, which provides an inviting environment for unwinding after a busy day out.

Take some time to reflect on your day and savor another beautiful night in Italy.

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Day10

Day 10

  • Venice - Departure day
  • More
  • Palazzo Contarini del Bovolo
  • More

Day 10 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Venice before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, we recommend visiting Palazzo Contarini Del Bovolo, an enchanting palace before you head out.

For a shopping spree in Venice, we recommend the lively Rialto Market. Here, you'll find a range of shops you can browse for some souvenir shopping.

Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Venice.

If you're in the mood to try something new, consider Trattoria Al Gazzettino, another top spot with a mouthwatering menu.

You’ll then say farewell to Venice. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!

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From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

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