10-Day Italy Self-Drive Road Trip With Itinerary from Venice traveling south to Florence, Rome, and Siena

Day 2 offers an itinerary packed with the best things to see in Venice. You’ll stay in Venice for 1 night more, offering you enough time to explore at a relaxed pace.

Make time for Peggy Guggenheim Collection, a captivating art gallery that is worthwhile a visit in the city. Nearby, you’ll find Teatro La Fenice, enchanting visitors with its romantic appeal. Continue your exploration at Piazza San Marco. This public square is one of the city’s most globally renowned spots.

Enjoy the freedom of exploring Venice at your own pace and find hidden gems along the way. If you want to see more picture-perfect spots, make sure to visit St Mark's Basilica. After exploring the church, head to the popular Doge's Palace. Lastly, wrap up today’s self-guided sightseeing tour with a visit to Bridge Of Sighs, a place of enchanting interest in Venice.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Venice. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Have a fantastic dining experience at Generator Venice, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Nevodi offers an enticing alternative with its varied menu. Additionally, Ristorante La Piazza is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Venice.

Keep the excitement of the evening going by visiting a bar or two. Il Mercante is an excellent place to start. You could also check out The Irish Pub Venezia, offering a different kind of charm. A last recommendation for the day is Ai Stagneri. This bar promises an enjoyable experience with tasty drinks and a vibrant setting.

Relax and look forward to more memorable moments to come!

Dive into day 3 of your remarkable road trip in Italy. Today you'll explore 1 destination, including Florence. At the end of the day, you’ll unwind at one of the finest accommodations in Florence, where you'll spend 2 nights.

Florence’s wonders await as you prepare for another journey on the road, leaving the breathtaking surroundings of Venice behind. This drive usually takes around 2 hours 56 min. Florence welcomes you with a multitude of unique vacation experiences.

Enjoy sightseeing at your own pace and allow yourself time to explore the beautiful surroundings. Take your self-guided tour to Basilica Of Santa Croce In Florence, a notable church that everyone visiting Florence should see. Next, head to Uffizi Gallery. This eye-catching art gallery is one of the most astonishing attractions in the region.

If you're keen to see more, don’t miss out on Ponte Vecchio, a visually striking historical landmark popular among locals as well as travelers. Loggia Dei Lanzi is an excellent attraction to visit next. Spend some time learning more about this worthwhile public square before you continue your journey. Lastly, visit Palazzo Vecchio, a history-steeped palace and a top attraction in the city.

At the end of the day, you will drive to Florence, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Florence. Enjoy a relaxing evening as you savor delicious local cuisine.

Have a fantastic dining experience at Ristorante Oliviero 1962, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Di Poneta Novoli offers an enticing alternative with its varied menu. Additionally, Caffe San Firenze is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Florence.

Continue your evening by exploring the vibrant nightlife scene at Manifattura, a prime destination for a thrilling night out. Also, don’t forget to check out Se·sto On Arno Rooftop Bar, a bar that offers unique local touches. Likewise, Il Vinile provides an excellent alternative for a fun evening.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in Italy.

On day 4 of your road trip, you'll get the chance to experience Florence and Pisa. At the end of the day, you'll drive back to Florence, where you still have 1 night left to stay.

Galleria Dell'accademia leaves a lasting impression. This art gallery is one of the most popular places to visit in Florence. Next, head to Museo Dell'opera Del Duomo, an increasingly popular museum, known for its noteworthy features.

In between the sights, don’t hesitate to take small detours to explore local stores and eateries. When you’re ready to continue your adventure, head to Florence Baptistery. This history-steeped church is a highly recommended experience.

Set your GPS to Pisa and hit the road. Expect a journey of approximately 1 hour 14 min without stops. Soak in the beautiful landscapes as you drive and look forward to exploring your next destination. Pisa beckons with new experiences!

Enjoy sightseeing at your own pace and allow yourself time to explore the beautiful surroundings. Take your self-guided tour to Leaning Tower Of Pisa, a wondrous monument that everyone visiting Pisa should see. Next, head to Piazza Del Duomo, Pisa. This historic public square is one of the most timeless attractions in the region.

If you're keen to see more, don’t miss out on Battistero Di San Giovanni, a historic church popular among locals as well as travelers.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Florence.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Florence, it's often a good idea to reserve a table in advance.

Treat yourself to a delicious dinner at Ditta Artigianale, an excellent option for tonight's dining. Looking for something different? Trattoria Da Burde offers a tantalizing alternative with its diverse menu. And don’t miss Casa Toscana. Known for great service, it’s a fantastic choice for tonight in Florence.

Extend your evening after a delightful meal by visiting Bar 50 Rosso, which offers the perfect atmosphere for a night out. Moreover, Bitter Bar is another popular option for a drink or two. Likewise, Archea Brewery also provides a great ambiance for reminiscing about the day and raising a toast to your vacation.

Head back to your accommodation in Florence and get some rest to prepare for another magical day of your road trip in Italy.

On day 5 of your road trip in Italy, your travel plans include 2 stops at the most scenic, wondrous, and interesting places in the region. Orvieto and Rome are on today's agenda. In the evening, you’ll end up in Rome, where you will stay for 3 nights.

It’s time to gear up for the next part of your road trip adventure. Under favorable conditions, your drive to Orvieto may take around 1 hour 58 min. Upon your arrival in Orvieto, you’ll be greeted with the opportunity to do some sightseeing and exploring.

When you're ready for some sights, head to Orvieto Cathedral, a locally renowned church in Orvieto. Explore its visually striking features at your own pace before you continue your journey.

Once you're ready to continue your road trip, it's time to buckle up and drive, eagerly anticipating your arrival in Rome. This drive usually takes around 1 hour 30 min, without any stops or traffic disruptions.

Enjoy sightseeing at your own pace and allow yourself time to explore the beautiful surroundings. Take your self-guided tour to Spanish Steps, a top-rated public square that everyone visiting Rome should see. Next, head to Piazza Di Spagna. This majestic public square is one of the most iconic attractions in the region.

If you're keen to see more, don’t miss out on Trevi Fountain, a romantic monument popular among locals as well as travelers. Pantheon is an excellent attraction to visit next. Spend some time learning more about this world-famous monument before you continue your journey. Lastly, visit Circus Maximus, a picture-perfect archeological site and a top attraction in the town.

When you’re done exploring for the day, you’ll drive to your hotel in Rome. Check in and relax before you head out to tour the city.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Rome. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Dine in style at La Bottega Roma, a top recommendation for dinner tonight. Or, for a change of pace, Pasta In Corso boasts a menu that's sure to impress. Also, be sure to check out Trattoria Vecchia Roma. Known as a local hotspot, it’s a great choice for tonight in Rome.

Continue your lively evening at La Botticella Of Poggi Giovanni, a perfect place for winding down or revving up the night, depending on which mood you’re in. Almalu Trastevere is another excellent bar that offers a great selection of drinks to suit any mood. If you prefer to go somewhere else, Bar Viminale Di Pepi Maurilio ensures a night out tailored to your taste.

Celebrate another amazing day of your road trip adventure in Italy!

Day 6 of your road trip across Italy promises a magnificent time exploring what to see in Rome. You have 2 nights left in Rome. Take the opportunity to experience more of the best attractions and activities in the city.

Rome is brimming with adventures.

Enjoy all that Colosseum has to offer. This is an iconic archeological site you should not miss. Another must-see is Roman Forum, a wondrous archeological site in Rome.

When you’re ready for the next sight, head to Altare Della Patria. From there, take a leisurely stroll to Campo De' Fiori, another of the city’s impressive attractions. We recommend continuing your self-guided tour at Piazza Navona, a history-steeped place of interest in the city. If time allows, add Castel Sant'angelo to your itinerary. This spectacular castle offers the perfect finishing touch to your day in Rome.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Rome. Enjoy a relaxing evening as you savor delicious local cuisine.

Dine in style at RomAntica, a top recommendation for dinner tonight. Or, for a change of pace, Coso Ristorante boasts a menu that's sure to impress. Also, be sure to check out DEROMA - Farine Romane. Known as a local hotspot, it’s a great choice for tonight in Rome.

Extend your evening after a delightful meal by visiting Sant' Eustachio Caffè, which offers the perfect atmosphere for a night out. Moreover, Yellowsquare Rome is another popular option for a drink or two. Likewise, Caffè Portofino also provides a great ambiance for reminiscing about the day and raising a toast to your vacation.

Get a good night's sleep and look forward to another great day on the road in Italy!

On day 7 of your road trip, you’ll start and end your day in Rome, where you have 1 night left to stay.

A top thing to do today is to explore Trastevere, a must-see neighborhood in Vatican City. It's the perfect starting point for touring the top attractions in the area.

No visit to Rome is complete without Piazza Del Popolo. This astonishing public square is one of the top attractions in the city.

Set your GPS to Vatican City and hit the road. Soak in the beautiful landscapes as you drive and look forward to exploring your next destination. Vatican City beckons with new experiences!

St. Peter's Basilica is an iconic major basilica we recommend visiting today.

When you’re done exploring for the day, you’ll return to Rome and your accommodation.

Rome is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Rome.

Enjoy a lovely meal at Hotel de Russie, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, La Taverna Italiana is another top choice with a popular menu. You could also check for a table at The Parrot Bar. As an establishment that consistently gains high praises from customers, it’s an ideal choice in Rome tonight.

Let the evening flow smoothly from dinner to drinks at The Apartment Bar Roma, a top-rated bar in the area. For other recommendations, Hotel Hassler Roma provides a perfect setting for rounding out your night with style and great drinks.

Take some time to reflect on your day and savor another beautiful night in Italy.

Experience an unparalleled adventure on day 8 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 place, which are Siena. At the end of the day, you will retreat to the hotel of your choice in Siena, where will spend 1 night.

Whether you decide to get entrance tickets for all attractions or you prefer admiring from a distance, amazing experiences await on this day in Siena.

Once you're ready to continue your road trip, it's time to buckle up and drive, eagerly anticipating your arrival in Siena. This drive usually takes around 2 hours 45 min, without any stops or traffic disruptions.

Porta Camollia, Siena is a curiosity-inducing monument we recommend visiting today. Discover its culturally significant features before continuing your self-guided tour to Basilica Of San Domenico, a picture-perfect church that’s well-regarded in the area.

Next, stop by Siena Cathedral, an enchanting church. While you’re nearby, don’t forget to visit Pubblico Palace, a breathtaking and truly unique palace. End your sightseeing at Piazza Del Campo, a spectacular public square that’s highly recommended by travelers passing through the city.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Siena. Siena offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

Siena is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Siena.

Savor the flavors at Enoteca I Terzi, a top pick for dinner tonight. Alternatively, Ristorante Tar-Tufo beckons with its unique menu offerings. Also, consider Antica Trattoria Papei. With its consistent customer satisfaction, it’s an excellent option for dining in Siena tonight.

Extend your evening after a delightful meal by visiting Meet Life Cafè, which offers the perfect atmosphere for a night out. Moreover, Maudit Pub is another popular option for a drink or two. Likewise, Bar Impero Siena also provides a great ambiance for reminiscing about the day and raising a toast to your vacation.

Raise your glass and celebrate another amazing day of your road trip in Italy!

On day 9 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, including Bologna. When you’re not sightseeing, take time to relax at your chosen hotel in Venice, where you’ll be staying for 1 night.

Embrace the thrill of the open road as you wave goodbye to Siena and set your GPS to Bologna. While on the road, immerse yourself in your favorite road trip tunes or sample the sounds from a local radio station. This car ride usually takes around 2 hours 1 min. Upon reaching Bologna, unwind, observe, and explore. The best things to do, see, and eat are waiting for you.

One of our top recommendations for your sightseeing is Palazzo Pallavicini. Spend some time admiring the romantic features of the palace before you continue to your next stop. Then, head to Chiesa Del Santissimo Salvatore. This up-and-coming church is a traveler-favorite in the city.

If you're keen to see more, continue to Piazza Maggiore. Feed your curiosity by learning something new about the public square. Next, take your journey to Two Towers, an interesting monument. Conclude your sightseeing at Bologna Cathedral, known for its grand features.

At the end of the day, you will drive to Venice, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Venice, it's often a good idea to reserve a table in advance.

Enjoy a lovely meal at Osteria Alla Staffa, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Bistrot de Venise is another top choice with a popular menu. You could also check for a table at Corte Sconta. As an establishment that consistently gains high praises from customers, it’s an ideal choice in Venice tonight.

After your delicious meal, get a taste of the vibrant nightlife with a visit to Dolce Vita Venezia, known for its inviting atmosphere. Tarnowska's American Bar is another great option if you’re looking for a place to get the night started. Similarly, Bar All'angolo provides a great setting to enjoy the night away.

Savor another day of unforgettable experiences in Italy!