10-Day Italy Self-Drive Road Trip With Itinerary from Venice traveling south to Florence, Rome, and Siena

Day 2 offers an itinerary packed with the best things to see in Venice. You’ll stay in Venice for 1 night more, offering you enough time to explore at a relaxed pace.

Peggy Guggenheim Collection makes a great addition to your morning plans. This captivating art gallery is a masterful place to see in Venice. Continue your discovery at Teatro La Fenice, a historic opera house with stories to tell.

As you stroll around Venice, take in the distinct atmosphere and learn what makes this city so unique. Maximize your sightseeing with a visit to Piazza San Marco. This wondrous public square offers a history-steeped encounter with Venice. Next, make your way to St Mark's Basilica to add another highlight to your day. After that, visit Doge's Palace, a popular palace that’s sure to impress. If you’re up for more, end your self-guided sightseeing tour at Bridge Of Sighs, an interesting monument in the city. Whether you decide to get entrance tickets for all attractions or you prefer admiring from a distance, amazing experiences await on this day in Venice.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Venice. Enjoy a relaxing evening as you savor delicious local cuisine.

Have a fantastic dining experience at Generator Venice, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Nevodi offers an enticing alternative with its varied menu. Additionally, Ristorante La Piazza is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Venice.

Explore the vibrant nightlife at Il Mercante after your meal, a hub for lively evenings and memorable moments. Or, head to The Irish Pub Venezia for a great selection of flavorful drinks and a charming setting. Furthermore, Ai Stagneri is perfect for those looking to extend their night with a touch of local flavor.

Savor another day of unforgettable experiences in Italy!

Experience an unparalleled adventure on day 3 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 place, which are Florence. At the end of the day, you will retreat to the hotel of your choice in Florence, where will spend 2 nights.

Let Basilica Of Santa Croce In Florence set the tone for the day. Spend some time admiring this culturally significant church before continuing your journey. Uffizi Gallery is your next stop. This top-rated art gallery is one of the best-rated sights in Venice.

Consider grabbing some lunch or a light snack to keep your energy going. Beyond the above-mentioned attractions, today is also the perfect time to visit Ponte Vecchio. This majestic historical landmark is a sight to behold. To round off your sightseeing experience, visit Loggia Dei Lanzi and Palazzo Vecchio. If time allows, end your day with Piazza Della Signoria, a grand public square that offers a memorable conclusion to your exploration.

At the end of the day, you will drive to Florence, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Florence, it's often a good idea to reserve a table in advance.

Make sure to reserve a table at Ristorante Oliviero 1962, an iconic dining spot in Florence. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Di Poneta Novoli, a popular restaurant in Florence. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Caffe San Firenze, a hidden gem nestled in Florence. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

After your delicious meal, get a taste of the vibrant nightlife with a visit to Manifattura, known for its inviting atmosphere. Se·sto On Arno Rooftop Bar is another great option if you’re looking for a place to get the night started. Similarly, Il Vinile provides a great setting to enjoy the night away.

Take some time to reflect on your day and savor another beautiful night in Italy.

On day 4 of your road trip in Italy, you’ll start and end your day in Florence, but spend the day exploring what’s beyond the city. Since you still have 1 night to spend in Florence, there’s no need to rush. Experience Florence and Pisa to the fullest today with this curated day itinerary.

Enjoy all that Galleria Dell'accademia has to offer. This is a captivating art gallery you should not miss. Another must-see is Museo Dell'opera Del Duomo, a beloved museum in Florence.

When you’re ready for the next sight, head to Florence Baptistery. From there, take a leisurely stroll to Leaning Tower Of Pisa, another of the city’s wondrous attractions. We recommend continuing your self-guided tour at Piazza Del Duomo, Pisa, a stunning place of interest in the city. If time allows, add Battistero Di San Giovanni to your itinerary. This curiosity-inducing church offers the perfect finishing touch to your day in Florence.

When you’re done exploring for the day, you’ll return to Florence and your accommodation.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Florence. Enjoy a relaxing evening as you savor delicious local cuisine.

Don’t miss out on dining at Ditta Artigianale, a top-rated dining destination in Florence. If you're in the mood to try something new, consider Trattoria Da Burde, another top spot with a mouthwatering menu. You might also want to secure a reservation at Casa Toscana. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Florence this evening.

Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, Bar 50 Rosso stands out as an excellent choice for a post-dinner cocktail. Alternatively, Bitter Bar offers an ideal atmosphere to enjoy the pleasures of the night. Archea Brewery is also a great option that provides a perfect setting for a relaxing evening.

Say good night to Florence and look forward to another great day of your road trip in Italy!

Dive into day 5 of your remarkable road trip in Italy. Today you'll explore 2 destinations, including Orvieto and Rome. At the end of the day, you’ll unwind at one of the finest accommodations in Rome, where you'll spend 3 nights.

Orvieto Cathedral is must-visit church and a great option for a daytime tour of the area. Continue your journey to Spanish Steps, an astonishing public square, located just a leisurely stroll away. Next, head to Piazza Di Spagna, an enchanting public square, also available for your discovery today.

Each stop on today’s itinerary promises to leave you with lasting memories and a deeper appreciation for Florence. When you're ready, let your sightseeing route take you to the globally renowned Trevi Fountain. If you’re looking for more, Pantheon is also an iconic attraction that is worthwhile a visit. Lastly, don’t miss Circus Maximus, a place of picture-perfect interest in the town.

When you’re done exploring for the day, you’ll drive to your hotel in Rome. Check in and relax before you head out to tour the city.

Indulge in a memorable dining experience at one of Rome's most popular restaurants, and connect with friendly locals for a true cultural experience.

Don’t miss out on dining at La Bottega Roma, a top-rated dining destination in Rome. If you're in the mood to try something new, consider Pasta In Corso, another top spot with a mouthwatering menu. You might also want to secure a reservation at Trattoria Vecchia Roma. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Rome this evening.

Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, La Botticella Of Poggi Giovanni stands out as an excellent choice for a post-dinner cocktail. Alternatively, Almalu Trastevere offers an ideal atmosphere to enjoy the pleasures of the night. Bar Viminale Di Pepi Maurilio is also a great option that provides a perfect setting for a relaxing evening.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in Italy.

Day 6 of your road trip across Italy promises a magnificent time exploring what to see in Rome. You have 2 nights left in Rome. Take the opportunity to experience more of the best attractions and activities in the city.

Look forward to a unique sightseeing adventure at the timeless Colosseum and allow yourself time to explore. Just a short distance away you'll find your next stop, Roman Forum, a picture-perfect archeological site that draws visitors from far and near.

Continue your journey to Altare Della Patria, one of the city’s most popular spots that you shouldn’t miss. Another great site to visit is the impressive Campo De' Fiori. When you're finished at the public square, Piazza Navona awaits your visit. This public square is a symbolic highlight on today's itinerary. Last up is a castle - the famous Castel Sant'angelo.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

Indulge in a memorable dining experience at one of Rome's most popular restaurants, and connect with friendly locals for a true cultural experience.

Enjoy a delicious meal at RomAntica, a highly-rated dining destination in Rome. If you're eager to try something different, consider Coso Ristorante, another top spot with a tantalizing menu. You might also want to secure a reservation at DEROMA - Farine Romane. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Rome this evening.

Round off your dining experience by visiting Sant' Eustachio Caffè, a prime location for a drink. Alternatively, explore the distinctive characteristics of Yellowsquare Rome, a bar catering to every mood and preference. Caffè Portofino likewise offers a unique atmosphere, perfect for a memorable night out.

Celebrate another amazing day of your road trip adventure in Italy!

On day 7 of your road trip, you’ll start and end your day in Rome, where you still have 1 night left. You'll spend part of the day exploring places of interest outside the immediate city, including Vatican City and Rome.

Whether you decide to explore Vatican City on foot, use public transport, or join a guided tour, there are a few attractions you don’t want to miss. Make sure to visit Trastevere, a popular neighborhood in Vatican City. Spend some time wandering around the area and soak in its distinctive charm. You’ll also discover that several of the city’s must-see attractions are just around the corner.

St. Peter's Basilica leaves a lasting impression. This major basilica is one of the most timeless places to visit in Rome.

Nearby, you'll also find Vatican Museums and Piazza Del Popolo. Visit these for an interesting touch to your journey.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Rome.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Rome. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Enjoy a lovely meal at Hotel de Russie, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, La Taverna Italiana is another top choice with a popular menu. You could also check for a table at The Parrot Bar. As an establishment that consistently gains high praises from customers, it’s an ideal choice in Rome tonight.

After enjoying a fulfilling meal, continue your evening at The Apartment Bar Roma, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, Hotel Hassler Roma offers a welcoming atmosphere for easing into the nightlife.

Savor another day of unforgettable experiences in Italy!

Your itinerary for day 8 of your road trip in Italy includes 1 stop and features some of the highlights of Siena. At the end of the day, enjoy the comforts of a top-rated hotel in Siena, where you'll spend 1 night.

Look forward to a unique sightseeing adventure at the locally appreciated Porta Camollia, Siena and allow yourself time to explore. Just a short distance away you'll find your next stop, Basilica Of San Domenico, a breathtaking church that draws visitors from far and near.

Continue your journey to Siena Cathedral, one of the city’s most well-known spots that you shouldn’t miss. Another great site to visit is the increasingly popular Pubblico Palace. When you're finished at the palace, Piazza Del Campo awaits your visit. This public square is a history-steeped highlight on today's itinerary. Last up is a monument - the intriguing Tower Of Mangia.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Siena. Siena offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Siena. Enjoy a relaxing evening as you savor delicious local cuisine.

Treat yourself to a delightful dinner at Enoteca I Terzi, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Ristorante Tar-Tufo? It's another excellent option with a diverse menu. Consider reserving a table at Antica Trattoria Papei as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Siena.

Keep the excitement of the evening going by visiting a bar or two. Meet Life Cafè is an excellent place to start. You could also check out Maudit Pub, offering a different kind of charm. A last recommendation for the day is Bar Impero Siena. This bar promises an enjoyable experience with tasty drinks and a vibrant setting.

Raise your glass to another unforgettable day in Italy!

On day 9 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, including Bologna. When you’re not sightseeing, take time to relax at your chosen hotel in Venice, where you’ll be staying for 1 night.

One of the most increasingly popular attractions included on the itinerary is Palazzo Pallavicini. This romantic palace will help you start your sightseeing on top. Then, take a leisurely stroll to Chiesa Del Santissimo Salvatore and learn what makes this culturally significant church unique.

Throughout the day, make sure to take breaks to appreciate the surroundings. Next up, visit the top-rated Piazza Maggiore. After exploring the public square, head to Two Towers. This notable monument is a highlight in Siena. As your day continues, stop by Bologna Cathedral, known for its awe-inspiring features. Lastly, don’t forget to check out the underrated Fountain Of Neptune, Bologna. Enjoy exploring this incredible monument at your own pace.

At the end of the day, you will drive to Venice, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Venice. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Savor the flavors at Osteria Alla Staffa, a top pick for dinner tonight. Alternatively, Bistrot de Venise beckons with its unique menu offerings. Also, consider Corte Sconta. With its consistent customer satisfaction, it’s an excellent option for dining in Venice tonight.

If you’re not ready to end the night just yet, Dolce Vita Venezia offers a perfect venue to relax and savor a drink. Similarly, Tarnowska's American Bar is well-suited for those looking to unwind in a social setting. Bar All'angolo is another excellent spot to enjoy a nightcap after a delightful meal.

As the sun sets, rest up and recharge for the next leg of your road trip in Italy.