10-Day Italy Self-Drive Road Trip With Itinerary from Venice traveling west to Verona, Florence, Siena, and Rome

1 / 88
Perfect travel plans
Everything included
Fully customizable

Description

Included

Flights
Hotel
Select dates
Car rental
Select dates
Tours & tickets
Select dates
Travel plan
From A to Z
Travel agent
24/7 fast service

Description

Experience the freedom of the open road on an unforgettable 10-day road trip in Italy! Embark on a self-drive tour that caters to every traveler, featuring destinations like Venice, Murano, Burano, Verona, Sirmione, Desenzano Del Garda, Gardone Riviera, Florence, Pisa, Siena, and Rome.

This perfectly planned road trip itinerary takes you through some of the best places to see in Italy. You will spend 3 nights in Venice, 2 nights in Verona, 2 nights in Florence, 1 night in Siena, and 1 night in Rome. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Venice, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Trevi Fountain and Colosseum are just a couple of the bucket-list attractions that await your discovery.

As you hit the open road and drive through Venice, Murano, Burano, Verona, Sirmione, Desenzano Del Garda, Gardone Riviera, Florence, Pisa, Siena, and Rome, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.

Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!

Read more

Travel details

Set your travel details to find the best price

Flights

Round trip
Round trip
Travel dates

Travelers

Rooms

Flights

Compare and choose from the best flights to Venice

Car

Choose from the best car rental deals or see all options

Driver’s age is 30 - 65
I live in
Pick-up: 10:00
Drop-off: 10:00

Personalize your itinerary

Customize tours under each day and destination

Day1

Day 1

  • Venice - Arrival day
  • More
  • Rialto Bridge
  • More

Your road trip adventure in Italy begins as soon as you reach Venice and pick up your car. You’ll stay here for 2 nights and explore what to see in Venice, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.

Venice is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Rialto Bridge. Taking a stroll in the city center is a great alternative. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

As afternoon approaches, head to your chosen hotel in Venice. Check-in typically starts around 2 to 4 PM at hotels in Italy. We recommend staying at a central location for easy access to key areas in the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Venice, it's often a good idea to reserve a table in advance.

Have a fantastic dining experience at Bauer Hotel, a highly recommended choice for tonight's dinner. If you're looking to mix things up, L'Osteria Le Guglie offers an enticing alternative with its varied menu. Additionally, Corner Pub is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Venice.

If you’re not ready to end the night just yet, Al Parlamento offers a perfect venue to relax and savor a drink. Similarly, The Caffe Rosso is well-suited for those looking to unwind in a social setting. Adagio is another excellent spot to enjoy a nightcap after a delightful meal.

Raise a toast to the start of your 10-day road trip in Italy!

Read more
Day2

Day 2

  • Venice
  • More

Drive 128 km, 2 hours 50 min

  • campo San Maurizio
  • St Mark's Basilica
  • Doge's Palace
  • Murano
  • Burano
  • More

Greet day 2 of your road trip in Italy with a smile and start your day with a hearty breakfast. You have 1 night to stay in Venice, so get ready to make the most of your time in the region. On the agenda for this day, you’ll find only the best things to see and do in Venice, Murano, and Burano.

Enjoy all that Campo San Maurizio has to offer. This is a frequently visited public square you should not miss. Another must-see is St Mark's Basilica, a locally renowned church in Venice.

When you’re ready for the next sight, head to Doge's Palace. From there, take a leisurely stroll to Murano, another of the city’s frequently visited attractions. We recommend continuing your self-guided tour at Burano, a romantic place of interest in the city.

When you’re done exploring for the day, you’ll return to Venice and your accommodation.

Indulge in a memorable dining experience at one of Venice's most popular restaurants, and connect with friendly locals for a true cultural experience.

Savor the flavors at Generator Venice, a top pick for dinner tonight. Alternatively, Nevodi beckons with its unique menu offerings. Also, consider Ristorante La Piazza. With its consistent customer satisfaction, it’s an excellent option for dining in Venice tonight.

Continue your lively evening at Il Mercante, a perfect place for winding down or revving up the night, depending on which mood you’re in. The Irish Pub Venezia is another excellent bar that offers a great selection of drinks to suit any mood. If you prefer to go somewhere else, Ai Stagneri ensures a night out tailored to your taste.

Savor another day of unforgettable experiences in Italy!

Read more
Day3

Day 3

  • Venice
  • Verona
  • More

Drive 119 km, 2 hours 4 min

  • Giusti Garden
  • piazza delle Erbe
  • Porta Borsari
  • Castelvecchio Museum
  • Castelvecchio Bridge
  • Verona Arena
  • More

On day 3 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, including Verona. When you’re not sightseeing, take time to relax at your chosen hotel in Verona, where you’ll be staying for 2 nights.

Awaiting your discovery is the intriguing Giusti Garden, a mesmerizing botanical garden in Venice. Next, go to Piazza Delle Erbe.

After visiting Giusti Garden and Piazza Delle Erbe, have a stroll along Venice's streets and take in the local charm. Continue your sightseeing by heading to Porta Borsari. This heritage-rich historical landmark offers a unique experience. Castelvecchio Museum is another noteworthy attraction worthwhile a visit. End your self-guided sightseeing tour on top with a visit to Castelvecchio Bridge, one of the most visually striking places to visit in Venice. If you still have some time left for sightseeing, we also recommend stopping by Verona Arena.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Verona. Verona offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

Verona is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Verona.

Make sure to reserve a table at La Griglia, an iconic dining spot in Verona. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Vecio Macello, a popular restaurant in Verona. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Via Fama Cafè | Verona, a hidden gem nestled in Verona. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

After your delicious meal, get a taste of the vibrant nightlife with a visit to Archivio, known for its inviting atmosphere. La Segreteria Café is another great option if you’re looking for a place to get the night started. Similarly, Grande Giove Cocktail Bar provides a great setting to enjoy the night away.

Take some time to reflect on your day and savor another beautiful night in Italy.

Read more
Day4

Day 4

  • Verona
  • More

Drive 149 km, 3 hours 32 min

  • Archaeological site of Grotte di Catullo
  • Castello di Sirmione
  • Castello di Desenzano del Garda
  • Duomo di Santa Maria Maddalena
  • Villa Romana di Desenzano del Garda
  • Vittoriale degli italiani
  • More

On day 4 of your road trip in Italy, you’ll start and end your day in Verona, but spend the day exploring what’s beyond the city. Since you still have 1 night to spend in Verona, there’s no need to rush. Experience Sirmione, Desenzano Del Garda, and Gardone Riviera to the fullest today with this curated day itinerary.

Make time for Archaeological Site Of Grotte Di Catullo, an interesting archeological site that is worthwhile a visit in the town. Nearby, you’ll find Scaliger Castle, enchanting visitors with its enchanting appeal. Continue your exploration at Castello Di Desenzano Del Garda. This castle is one of the town’s most locally appreciated spots.

Enjoy the freedom of exploring Verona at your own pace and find hidden gems along the way. If you want to see more picture-perfect spots, make sure to visit Duomo Di Santa Maria Maddalena. After exploring the church, head to the increasingly popular Villa Romana Di Desenzano Del Garda. Lastly, wrap up today’s self-guided sightseeing tour with a visit to Vittoriale Degli Italiani, a place of awe-inspiring interest in Verona.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Verona.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Verona, it's often a good idea to reserve a table in advance.

Enjoy a delicious meal at Trattoria I Masenini, a top-rated dining destination in Verona. If you're in the mood to try something new, consider Osteria da Ugo, another top spot with a mouthwatering menu. You might also want to secure a reservation at Locanda 4 Cuochi. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Verona this evening.

Following your dinner, dive into the local bar culture at Duchi Café. Enjoy this evening's relaxed ambiance with delightful drinks. Alternatively, go to Cambridge Bar, the perfect place for those looking to experience the best of the nightlife. Similarly, Rubicone Caffe provides excellent drinks and a great atmosphere, ensuring a memorable night out.

Get a good night's sleep and look forward to another great day on the road in Italy!

Read more
Day5

Day 5

  • Verona
  • Florence
  • More

Drive 237 km, 3 hours 4 min

  • Piazza della Repubblica
  • Ponte Vecchio
  • Uffizi Gallery
  • Basilica of Santa Croce in Florence
  • Palazzo Vecchio
  • piazza della Signoria
  • More

Dive into day 5 of your remarkable road trip in Italy. Today you'll explore 1 destination, including Florence. At the end of the day, you’ll unwind at one of the finest accommodations in Florence, where you'll spend 2 nights.

Piazza Della Repubblica is perfect for a self-paced visit during the day. This visually striking public square is sure to impress. Next on your list is Ponte Vecchio, another must-visit landmark and globally renowned historical landmark renowned for its enchanting features.

While exploring and sightseeing, take time to savor the culture of Verona by sampling some local delicacies. When you’re ready for more sightseeing, head to Uffizi Gallery. This romantic art gallery is an essential place to visit for anyone looking for the full Verona experience. We also recommend visiting Basilica Of Santa Croce In Florence, a captivating church. Nearby, you'll also find Palazzo Vecchio, ready to add charm to your journey. End your self-guided sightseeing tour with a stop at Piazza Della Signoria and wrap up your day with its romantic appeal.

At the end of the day, you will drive to Florence, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Florence. Enjoy a relaxing evening as you savor delicious local cuisine.

Treat yourself to a delightful dinner at Ristorante Oliviero 1962, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Di Poneta Novoli? It's another excellent option with a diverse menu. Consider reserving a table at Caffe San Firenze as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Florence.

Following your dinner, dive into the local bar culture at Manifattura. Enjoy this evening's relaxed ambiance with delightful drinks. Alternatively, go to Se·sto On Arno Rooftop Bar, the perfect place for those looking to experience the best of the nightlife. Similarly, Il Vinile provides excellent drinks and a great atmosphere, ensuring a memorable night out.

Raise your glass to another unforgettable day in Italy!

Read more
Day6

Day 6

  • Florence
  • More

Drive 176 km, 3 hours 2 min

  • Santa Maria della Spina
  • Putti fountain
  • Leaning Tower of Pisa
  • Pisa Cathedral
  • Piazza del Duomo, Pisa
  • Campo santo
  • More

Wake up to day 6 of your road trip in Italy. On this day, you’ll embark on an exciting expedition discovering the enchanting sights and activities of Pisa. With 1 night to stay in Florence, we encourage you to seize the day and discover the unexplored beauty of the city’s surroundings!

Awaiting your discovery is the often recommended Santa Maria Della Spina, a visually striking church in Florence. Next, go to Putti Fountain.

After visiting Santa Maria Della Spina and Putti Fountain, have a stroll along Florence's streets and take in the local charm. Continue your sightseeing by heading to Leaning Tower Of Pisa. This picture-perfect monument offers a unique experience. Pisa Cathedral is another noteworthy attraction worthwhile a visit. End your self-guided sightseeing tour on top with a visit to Piazza Del Duomo, Pisa, one of the most breathtaking places to visit in Florence. If you still have some time left for sightseeing, we also recommend stopping by Campo Santo.

When you’re done exploring for the day, you’ll return to Florence and your accommodation.

Florence is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Florence.

Treat yourself to a wonderful meal at Ditta Artigianale, a top-rated dining spot in Florence. If you're in the mood for something new, try Trattoria Da Burde, another premier location with a delectable menu. You might also want to book a table at Casa Toscana. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Florence.

Keep the evening going at Bar 50 Rosso, a great choice for enjoying the after-dinner hours with a drink. You could also go to Bitter Bar, which offers a similarly pleasant setting and great drinks. Another option is Archea Brewery, which provides an inviting environment for unwinding after a busy day out.

Head back to your accommodation in Florence and get some rest to prepare for another magical day of your road trip in Italy.

Read more
Day7

Day 7

  • Florence
  • Siena
  • More

Drive 79 km, 1 hour 31 min

  • Basilica of San Domenico
  • Siena Cathedral
  • Pubblico Palace
  • piazza del Campo
  • Tower of Mangia
  • Loggia del Papa, Siena
  • More

Experience an unparalleled adventure on day 7 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 place, which are Siena. At the end of the day, you will retreat to the hotel of your choice in Siena, where will spend 1 night.

Make time for Basilica Of San Domenico, an often recommended church that is worthwhile a visit in the city. Nearby, you’ll find Siena Cathedral, enchanting visitors with its inviting appeal. Continue your exploration at Pubblico Palace. This palace is one of the city’s most locally appreciated spots.

Enjoy the freedom of exploring Florence at your own pace and find hidden gems along the way. If you want to see more picture-perfect spots, make sure to visit Piazza Del Campo. After exploring the public square, head to the intriguing Tower Of Mangia. Lastly, wrap up today’s self-guided sightseeing tour with a visit to Loggia Del Papa, Siena, a place of symbolic interest in Florence.

When you’re done exploring for the day, you’ll drive to your hotel in Siena. Check in and relax before you head out to tour the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Siena, it's often a good idea to reserve a table in advance.

Make sure to reserve a table at Enoteca I Terzi, an iconic dining spot in Siena. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Ristorante Tar-Tufo, a popular restaurant in Siena. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Antica Trattoria Papei, a hidden gem nestled in Siena. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Round off your dining experience by visiting Meet Life Cafè, a prime location for a drink. Alternatively, explore the distinctive characteristics of Maudit Pub, a bar catering to every mood and preference. Bar Impero Siena likewise offers a unique atmosphere, perfect for a memorable night out.

Head back to your accommodation in Siena and get some rest to prepare for another magical day of your road trip in Italy.

Read more
Day8

Day 8

  • Siena
  • Rome
  • More

Drive 247 km, 3 hours 32 min

  • Colosseum
  • Roman Forum
  • St Peter's Basilica
  • Piazza Navona
  • More

Your itinerary for day 8 of your road trip in Italy includes 2 stops and features some of the highlights of Rome and Vatican City. At the end of the day, enjoy the comforts of a top-rated hotel in Rome, where you'll spend 1 night.

Let Colosseum set the tone for the day. Spend some time admiring this awe-inspiring archeological site before continuing your journey. Roman Forum is your next stop. This iconic archeological site is one of the best-rated sights in Siena.

Consider grabbing some lunch or a light snack to keep your energy going. Beyond the above-mentioned attractions, today is also the perfect time to visit St. Peter's Basilica. To round off your sightseeing experience, visit Piazza Navona.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Rome. Rome offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a day of adventure, treat yourself to an exquisite dinner at one of Rome's best restaurants.

Savor the flavors at La Bottega Roma, a top pick for dinner tonight. Alternatively, Pasta In Corso beckons with its unique menu offerings. Also, consider Trattoria Vecchia Roma. With its consistent customer satisfaction, it’s an excellent option for dining in Rome tonight.

Extend your evening after a delightful meal by visiting La Botticella Of Poggi Giovanni, which offers the perfect atmosphere for a night out. Moreover, Almalu Trastevere is another popular option for a drink or two. Likewise, Bar Viminale Di Pepi Maurilio also provides a great ambiance for reminiscing about the day and raising a toast to your vacation.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in Italy.

Read more
Day9

Day 9

  • Rome
  • Venice
  • More

Drive 530 km, 6 hours 2 min

  • Pantheon
  • Trevi Fountain
  • Piazza di Spagna
  • Spanish Steps
  • More

On day 9 of your road trip in Italy, your travel plans include 1 stop at the most scenic, wondrous, and interesting places in the region. Rome are on today's agenda. In the evening, you’ll end up in Venice, where you will stay for 1 night.

Pantheon is an ideal stop early in the day. This globally renowned monument is a must-visit in the city. When you’re ready for your next discovery, continue to Trevi Fountain, which may be one of the most symbolic places you will experience today.

One of the best things about exploring Rome on a self-guided tour is that you set the pace. There’s plenty of time for detours and discovering hidden gems. When you’re ready for your next stop, make your way to Piazza Di Spagna, a globally renowned public square in the city. If you’re up for more discoveries, don’t forget to reserve some time for Spanish Steps.

At the end of the day, you will drive to Venice, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

Indulge in a memorable dining experience at one of Venice's most popular restaurants, and connect with friendly locals for a true cultural experience.

Enjoy a delicious meal at Osteria Alla Staffa, a top-rated dining destination in Venice. If you're in the mood to try something new, consider Bistrot de Venise, another top spot with a mouthwatering menu. You might also want to secure a reservation at Corte Sconta. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Venice this evening.

Continue your evening by exploring the vibrant nightlife scene at Dolce Vita Venezia, a prime destination for a thrilling night out. Also, don’t forget to check out Tarnowska's American Bar, a bar that offers unique local touches. Likewise, Bar All'angolo provides an excellent alternative for a fun evening.

As the sun sets, rest up and recharge for the next leg of your road trip in Italy.

Read more
Day10

Day 10

  • Venice - Departure day
  • More
  • Grand Canal
  • More

Day 10 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Venice before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, we recommend visiting Grand Canal, an enchanting street before you head out.

Take advantage of your accommodation's proximity to Venice’s shopping district for some last-minute bargain hunting. Explore local shops for souvenirs to remember your trip or find unique gifts for loved ones. For those seeking luxury items, check out the area’s high-end stores.

Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Venice.

Enjoy a lovely meal at Cantina Do Spade, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Trattoria Al Gazzettino is another top choice with a popular menu.

You’ll then say farewell to Venice. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!

Read more

How it works

Book your journey with Europe’s biggest travel platform—expert itineraries, instant confirmation, and full flexibility with 24/7 support.

Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

We guarantee

Your trip is protected, personalized, and priced right. No surprises, no stress.

Similar travel packages

Discover other popular vacations in Italy

Link to appstore phone
Install Europe’s biggest travel app

Download Europe’s biggest travel marketplace to your phone to manage your entire trip in one place

Scan this QR code with your phone camera and press the link that appears to add Europe’s biggest travel marketplace into your pocket. Enter your phone number or email address to receive an SMS or email with the download link.