10-Day Italy Self-Drive Road Trip With Itinerary from Venice traveling west to Verona, Florence, Siena, and Rome

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Experience the freedom of the open road in Italy as you embark on an unforgettable 10-day road trip! This experience caters to every traveler, featuring destinations like Venice, Murano, Burano, Verona, Sirmione, Desenzano Del Garda, Gardone Riviera, Florence, Pisa, Siena, and Rome.

This perfectly planned road trip itinerary in Italy takes you through some of the best places to see in the country. You will spend 3 nights in Venice, 2 nights in Verona, 2 nights in Florence, 1 night in Siena, and 1 night in Rome. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Venice, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Trevi Fountain and Colosseum are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Pantheon, learn more about the unique Piazza Navona, and immerse yourself in the vibrant atmosphere of Rialto Bridge.

As you hit the open road and drive through Venice, Murano, Burano, Verona, Sirmione, Desenzano Del Garda, Gardone Riviera, Florence, Pisa, Siena, and Rome, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.

Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!

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Day 1

Day 1

  • Venice - Arrival day
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  • Rialto Bridge
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Your road trip adventure in Italy begins as soon as you reach Venice and pick up your car. You’ll stay in Venice for 2 nights and explore the best things to see and do, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.

Venice is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Rialto Bridge, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Make your way to your chosen hotel. Check-in typically starts between 2 and 4 PM in Venice. Make yourself at home and enjoy some downtime before heading out again.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Venice, it's often a good idea to reserve a table in advance.

Savor the flavors at Bauer Hotel, a top pick for dinner tonight. Alternatively, L'Osteria Le Guglie beckons with its unique menu offerings. Also, consider Corner Pub. With its consistent customer satisfaction, it’s an excellent option for dining in Venice tonight.

Continue the enjoyment post-dinner at Al Parlamento, a cherished local gathering spot renowned for its welcoming atmosphere. Similarly, The Caffe Rosso offers a vibrant space for indulging in well-crafted drinks and engaging conversation. You may also want to check out Adagio. This bar is a favorite among both locals and visitors looking for a delightful evening out filled with laughter and fun.

Raise a toast to the start of your 10-day road trip in Italy!

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Day 2

Day 2

  • Venice
  • More

Drive 128 km, 2 hours 50 min

  • campo San Maurizio
  • St Mark's Basilica
  • Doge's Palace
  • Murano
  • Burano
  • More

Wake up to day 2 of your extraordinary road trip in Italy. With 1 night left in Venice, we encourage you to seize the day and discover the unexplored beauty of the city’s surroundings!

Today’s well-planned self-sightseeing route offers several family-friendly attractions, romantic experiences, and breathtaking views. Whether you decide to explore Venice on foot, use public transport, or join a guided tour, there are a few attractions you don’t want to miss. Campo San Maurizio is the first of them. Spend some time admiring this visually striking public square before continuing your journey. St Mark's Basilica is your next stop. This captivating church is one of the best-rated sights in Venice.

Consider grabbing some lunch or a light snack to keep your energy going. Beyond the above-mentioned attractions, today is also the perfect time to visit Doge's Palace. This history-steeped palace is a sight to behold. To round off your sightseeing experience, visit Murano and Burano.

When you’re done exploring for the day, you’ll return to Venice and your accommodation.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Venice. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Don’t miss out on dining at Generator Venice, a top-rated dining destination in Venice. If you're in the mood to try something new, consider Nevodi, another top spot with a mouthwatering menu. You might also want to secure a reservation at Ristorante La Piazza. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Venice this evening.

Continue the enjoyment post-dinner at Il Mercante, a cherished local gathering spot renowned for its welcoming atmosphere. Similarly, The Irish Pub Venezia offers a vibrant space for indulging in well-crafted drinks and engaging conversation. You may also want to check out Ai Stagneri. This bar is a favorite among both locals and visitors looking for a delightful evening out filled with laughter and fun.

Celebrate another amazing day of your road trip adventure in Italy!

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Day 3

Day 3

  • Venice
  • Verona
  • More

Drive 119 km, 2 hours 4 min

  • Giusti Garden
  • piazza delle Erbe
  • Porta Borsari
  • Castelvecchio Museum
  • Castelvecchio Bridge
  • Verona Arena
  • More

On day 3 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, Verona. When you’re not sightseeing, take time to relax at your selected hotel in Verona, where you’ll be staying for 2 nights.

Bring your curiosity for today’s adventure around Venice. Some of the city’s most loved attractions await! Giusti Garden is the perfect place to start. This botanical garden is one of the most often recommended places to visit in Venice. Next, head to Piazza Delle Erbe, a notable public square, known for its history-steeped features.

In between the sights, don’t hesitate to take small detours to explore local stores and eateries. When you’re ready to continue your adventure, head to Porta Borsari. This heritage-rich historical landmark is a highly recommended experience. Nearby, you'll also find Castelvecchio Museum and Castelvecchio Bridge. Visit these for an interesting touch to your journey. Finish the day with a visit to Verona Arena, a visually striking stadium in Venice.

At the end of the day, you will drive to Verona, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Verona. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Enjoy a delicious meal at La Griglia, a top-rated dining destination in Verona. If you're in the mood to try something new, consider Vecio Macello, another top spot with a mouthwatering menu. You might also want to secure a reservation at Via Fama Cafè | Verona. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Verona this evening.

To truly maximize your evening out, consider visiting Archivio after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to La Segreteria Café, another bar with an inviting ambiance. Similarly, Grande Giove Cocktail Bar also offers a great atmosphere, ensuring a night filled with enjoyment and relaxation.

Savor another day of unforgettable experiences in Italy!

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Day 4

Day 4

  • Verona
  • More

Drive 149 km, 3 hours 32 min

  • Archaeological site of Grotte di Catullo
  • Castello di Sirmione
  • Castello di Desenzano del Garda
  • Duomo di Santa Maria Maddalena
  • Villa Romana di Desenzano del Garda
  • Vittoriale degli italiani
  • More

Greet day 4 of your road trip in Italy with a smile and start your day with a hearty breakfast. You will return to Verona for your remaining 1 night in the city later today, but first, it’s time for some exploring! On the agenda for this day, you’ll find only the best things to see and do in Sirmione, Desenzano Del Garda, and Gardone Riviera.

Verona is home to plenty of attractions that offer family-friendly attractions, romantic experiences, and scenic views! Start at Archaeological Site Of Grotte Di Catullo, an interesting archeological site that is worthwhile a visit in the town. Nearby, you’ll find Scaliger Castle, enchanting visitors with its symbolic appeal. Continue your exploration at Castello Di Desenzano Del Garda. This castle is one of the town’s most up-and-coming spots.

Enjoy the freedom of exploring Verona at your own pace and find hidden gems along the way. If you want to see more picture-perfect spots, make sure to visit Duomo Di Santa Maria Maddalena. After exploring the church, head to the beloved Villa Romana Di Desenzano Del Garda. Lastly, wrap up today’s self-guided sightseeing tour with a visit to Vittoriale Degli Italiani, a place of breathtaking interest in Verona.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Verona.

As dinnertime approaches, it's time to head out for a bite to eat in Verona. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Savor the flavors at Trattoria I Masenini, a top pick for dinner tonight. Alternatively, Osteria da Ugo beckons with its unique menu offerings. Also, consider Locanda 4 Cuochi. With its consistent customer satisfaction, it’s an excellent option for dining in Verona tonight.

After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at Duchi Café, a well-loved spot among locals and tourists. Or, head to Cambridge Bar. This bar boasts a welcoming environment that is perfect for winding down. You could also continue your night at Rubicone Caffe, another top-rated place in the area.

Head back to your accommodation in Verona and get some rest in preparation for another magical day of your road trip in Italy!

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Day 5

Day 5

  • Verona
  • Florence
  • More

Drive 237 km, 3 hours 4 min

  • Piazza della Repubblica
  • Ponte Vecchio
  • Uffizi Gallery
  • Basilica of Santa Croce in Florence
  • Palazzo Vecchio
  • piazza della Signoria
  • More

Dive into day 5 of your remarkable road trip in Italy. Today you will explore Florence, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Florence. You’ll stay here for 2 nights.

Set out on a day brimming with fun adventures, romantic experiences, and breathtaking views. Start at the interesting Piazza Della Repubblica, a romantic public square in Verona. Next, go to Ponte Vecchio.

After visiting Piazza Della Repubblica and Ponte Vecchio, have a stroll along Verona's streets and take in the local charm. Continue your sightseeing by heading to Uffizi Gallery. This romantic art gallery offers a unique experience. Basilica Of Santa Croce In Florence is another noteworthy attraction worthwhile a visit. End your self-guided sightseeing tour on top with a visit to Palazzo Vecchio, one of the most majestic places to visit in Verona. If you still have some time left for sightseeing, we also recommend stopping by Piazza Della Signoria.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Florence. Florence offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

Indulge in a memorable dining experience at one of Florence's most popular restaurants, and connect with friendly locals for an authentic adventure.

Dine in style at Ristorante Oliviero 1962, a top recommendation for dinner tonight. Or, for a change of pace, Di Poneta Novoli boasts a menu that's sure to impress. Also, be sure to check out Caffe San Firenze. Known as a local hotspot, it’s a great choice for tonight in Florence.

After your delicious meal, get a taste of the vibrant nightlife with a visit to Manifattura, known for its inviting atmosphere. Se·sto On Arno Rooftop Bar is another great option if you’re looking for a place to get the night started. Similarly, Il Vinile provides a great setting to enjoy the night away.

Raise your glass to another unforgettable day in Italy!

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Day 6

Day 6

  • Florence
  • More

Drive 176 km, 3 hours 2 min

  • Santa Maria della Spina
  • Putti fountain
  • Leaning Tower of Pisa
  • Pisa Cathedral
  • Piazza del Duomo, Pisa
  • Campo santo
  • More

At the end of the day, you'll drive back to Florence, where you'll stay for 1 night more.

A blend of family-friendly attractions, romantic experiences, and scenic views await you in Florence on today’s itinerary. First up is the increasingly popular church, Santa Maria Della Spina. Afterward, continue to Putti Fountain, a fountain every traveler should visit.

As you explore Florence’s charming streets, take in the lively atmosphere and get to know the character of the city. Next, make your way to Leaning Tower Of Pisa. This timeless monument is an essential stop. Following that, head to Pisa Cathedral, another must-visit site that will enhance your experience. Don’t forget to stop by Piazza Del Duomo, Pisa, a globally renowned public square in the city. Finally, end your day with a visit to Campo Santo, a historic cemetery that offers the perfect conclusion to your sightseeing of the day.

When you’re done exploring for the day, you’ll return to Florence and your accommodation.

After a day of adventure, treat yourself to an exquisite dinner at one of Florence's best restaurants.

Dine in style at Ditta Artigianale, a top recommendation for dinner tonight. Or, for a change of pace, Trattoria Da Burde boasts a menu that's sure to impress. Also, be sure to check out Casa Toscana. Known as a local hotspot, it’s a great choice for tonight in Florence.

Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, Bar 50 Rosso stands out as an excellent choice for a post-dinner cocktail. Alternatively, Bitter Bar offers an ideal atmosphere to enjoy the pleasures of the night. Archea Brewery is also a great option that provides a perfect setting for a relaxing evening.

Relax and recharge in preparation for another adventurous day in Italy!

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Day 7

Day 7

  • Florence
  • Siena
  • More

Drive 79 km, 1 hour 31 min

  • Basilica of San Domenico
  • Siena Cathedral
  • Pubblico Palace
  • piazza del Campo
  • Tower of Mangia
  • Loggia del Papa, Siena
  • More

Embark on another extraordinary experience on day 7 of your road trip in Italy. Today, you will make 1 stop and experience some of the highlights of Siena. At the end of the day, you will enjoy the comforts of a top-rated hotel in Siena, which will be your home away from home for 1 night.

Today's adventure in Florence promises more breathtaking discoveries and enriching experiences! Begin at Basilica Of San Domenico. This picture-perfect church is a highlight of any visit in the city. Then, enjoy Siena Cathedral, another majestic attraction that never fails to captivate visitors. Next, head over to Pubblico Palace, one of the city’s most underrated attractions, known for its awe-inspiring features.

If you’re looking for more, spend time soaking in the atmosphere of Piazza Del Campo. This enchanting public square is frequented by locals and tourists alike. To complete your memorable day, make sure to visit Tower Of Mangia, a locally appreciated monument, and take a stroll around the area. If you want to extend your self-guided sightseeing tour, go check out Loggia Del Papa, Siena before you head back to your hotel.

When you’re done exploring for the day, you’ll drive to your hotel in Siena. Check in and spend some time relaxing before you head out to tour the city.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Siena. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Have a fantastic dining experience at Enoteca I Terzi, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Ristorante Tar-Tufo offers an enticing alternative with its varied menu. Additionally, Antica Trattoria Papei is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Siena.

After enjoying a fulfilling meal, continue your evening at Meet Life Cafè, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, Maudit Pub offers a welcoming atmosphere for easing into the nightlife. Similarly, Bar Impero Siena provides an excellent environment for a relaxed and enjoyable evening.

Take some time to reflect on your day and savor another beautiful night in Italy.

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Day 8

Day 8

  • Siena
  • Rome
  • More

Drive 247 km, 3 hours 32 min

  • Colosseum
  • Roman Forum
  • St Peter's Basilica
  • Piazza Navona
  • More

On day 8 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Rome and Vatican City. In the evening, you’ll end up in Rome, where you will stay for 1 night.

Immerse yourself in Siena’s rich culture with today's sightseeing itinerary. Start your journey at Colosseum. This UNESCO world heritage-listed archeological site is sure to ignite your curiosity. Next, dive into the picture-perfect features of Roman Forum, a must-visit archeological site in the city.

In between sights, stop by local stores, picturesque photo spots, and small eateries. When you’re ready for your next attraction, proceed to St. Peter's Basilica, a wondrous major basilica. For a change of scene, check out Piazza Navona, known for its noteworthy features.

At the end of the day, you will drive to Rome, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As dinnertime approaches, it's time to head out for a bite to eat in Rome. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Enjoy a lovely meal at La Bottega Roma, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Pasta In Corso is another top choice with a popular menu. You could also check for a table at Trattoria Vecchia Roma. As an establishment that gains consistently high praises from customers, it’s an ideal choice in Rome tonight.

After savoring a delicious meal, step into the vibrant nightlife at La Botticella Of Poggi Giovanni, where the evening is just getting started. In the same way, Almalu Trastevere offers a unique charm perfect for experiencing the local bar scene in Rome. Bar Viminale Di Pepi Maurilio is another top-recommended bar that is sure to get you into the mood for some dancing and celebrating.

Celebrate another amazing day of your road trip adventure in Italy!

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Day 9

Day 9

  • Rome
  • Venice
  • More

Drive 530 km, 6 hours 2 min

  • Pantheon
  • Trevi Fountain
  • Piazza di Spagna
  • Spanish Steps
  • More

Experience an unparalleled adventure on day 9 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 vibrant destinations - Rome. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Venice. You will spend 1 night here for some well-deserved relaxation.

Today, you'll explore some of the most beautiful places in Rome, including a monument and a public square. Start your day with a visit to Pantheon. This iconic monument is a must-visit in the city. When you’re ready for your next discovery, continue to Trevi Fountain, which may be one of the most detailed places you will experience today.

One of the best things about exploring Rome on a self-guided tour is that you set the pace. There’s plenty of time for detours and discovering hidden gems. When you’re ready for your next stop, make your way to Piazza Di Spagna, a wondrous public square in the city. If you’re up for more discoveries, don’t forget to reserve some time for Spanish Steps.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Venice. Venice offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a day of adventure, treat yourself to an exquisite dinner at one of Venice's best restaurants.

Treat yourself to a delicious dinner at Osteria Alla Staffa, an excellent option for tonight's dining. Looking for something different? Bistrot de Venise offers a tantalizing alternative with its diverse menu. And don’t miss Corte Sconta. With its reputation for pleasing customers, it’s a fantastic choice for tonight in Venice.

Continue your evening by exploring the vibrant nightlife scene at Dolce Vita Venezia, a prime destination for a thrilling night out. Also, don’t forget to check out Tarnowska's American Bar, a bar that offers unique local touches. Likewise, Bar All'angolo provides an excellent alternative for a fun evening.

Get a good night's sleep and look forward to another great day on the road in Italy!

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Day 10

Day 10

  • Venice - Departure day
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  • Grand Canal
  • More

Day 10 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Venice before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, begin at Grand Canal. This up-and-coming street is a popular place to see in the city.

Explore local shops for souvenirs to remember your trip or find unique gifts for loved ones. For those seeking luxury items, check out the area’s high-end stores.

Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Venice.

Savor the flavors at Cantina Do Spade, a top pick for dinner tonight. Alternatively, Trattoria Al Gazzettino beckons with its unique menu offerings.

You’ll then say farewell to Venice. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!

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Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

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