11-Day Italy Self-Drive Road Trip With Itinerary from Genoa to Florence and Rome
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Experience the freedom of the open road in Italy as you embark on an unforgettable 11-day road trip! This experience caters to every traveler, featuring destinations like Genoa, Monterosso al Mare, Corniglia, Manarola, Riomaggiore, Pisa, Florence, Siena, Santa Maria degli Angeli, Rome, and Orvieto.
This perfectly planned road trip itinerary in Italy takes you through some of the best places to see in the country. You will spend 4 nights in Genoa, 3 nights in Florence, and 3 nights in Rome. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!
With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.
Upon arriving in Genoa, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.
An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Trevi Fountain and Colosseum are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Pantheon, learn more about the unique Piazza Navona, and immerse yourself in the vibrant atmosphere of St. Peter's Basilica.
As you hit the open road and drive through Genoa, Monterosso al Mare, Corniglia, Manarola, Riomaggiore, Pisa, Florence, Siena, Santa Maria degli Angeli, Rome, and Orvieto, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.
Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.
This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.
The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!
Itinerary summary
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Day 1
- Genoa - Arrival day
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- piazza De Ferrari
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Say hello to Genoa! Your exciting road trip through Italy is just about to start. Navigating the top places to see in the region is a breeze with a car. The rental vehicle of your choice will be ready for pickup upon your arrival in the city. You will stay in Genoa for 3 nights before you continue your adventure!
Genoa is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Piazza De Ferrari, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.
Make your way to your chosen hotel. Check-in typically starts between 2 and 4 PM in Genoa. Make yourself at home and enjoy some downtime before heading out again.
As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Genoa, it's often a good idea to reserve a table in advance.
Enjoy a delicious meal at 7 Sensi cucina decontaminata, a top-rated dining destination in Genoa. If you're in the mood to try something new, consider Alla Lunga Ristorante, another top spot with a mouthwatering menu. You might also want to secure a reservation at Grand Hotel Savoia. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Genoa this evening.
After your meal, keep the night alive at a bar like Scurreria Beer & Bagel, known for its lively atmosphere. La Lepre is another top recommendation that provides the perfect setting with well-crafted drinks and a welcoming ambiance. Similarly, Bar Pisacane Iii offers an excellent atmosphere for those looking to amp up the evening.
Raise a toast to the start of your 11-day road trip in Italy!
Day 2
- Genoa
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Drive 16 km, 57 min
- Aquarium of Genoa
- Palazzo Spinola National Gallery
- Via Garibaldi
- Palazzo Podestà
- Lighthouse of Genoa
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Day 2 offers a multitude of experiences. You will stay in Genoa for 2 nights more, offering you enough time to explore at a relaxed pace.
Today, you'll explore some of the most beautiful places in Genoa, including an aquarium, an art gallery, a street, a palace, a lighthouse and much more! Start your day with a visit to Aquarium Of Genoa. This famous aquarium is a must-visit in the city. When you’re ready for your next discovery, continue to Palazzo Spinola National Gallery, which may be one of the most history-steeped places you will experience today.
One of the best things about exploring Genoa on a self-guided tour is that you set the pace. There’s plenty of time for detours and discovering hidden gems. When you’re ready for your next stop, make your way to Via Garibaldi, a curiosity-inducing street in the city. If you’re up for more discoveries, don’t forget to reserve some time for Palazzo Podestà and Lighthouse Of Genoa.
Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.
After a day of adventure, treat yourself to an exquisite dinner at one of Genoa's best restaurants.
Treat yourself to a delightful dinner at Zeffirino, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Trattoria Vegia Zena? It's another excellent option with a diverse menu. Consider reserving a table at Trattoria delle Grazie as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Genoa.
Relax and reminisce about your day in Italy and look forward to more memorable moments to come!
Day 3
- Genoa
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Drive 244 km, 4 hours 39 min
- Parrocchia di S. Giovanni Battista
- Cinque Terre National Park
- Manarola Overlook Viewpoint
- Riomaggiore
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On day 3 of your road trip, you’ll start and end your day in Genoa, but spend part of the day exploring places of interest outside the immediate city. On today's itinerary, you'll find attractions in Monterosso al Mare, Corniglia, Manarola, and Riomaggiore. You still have 1 night left in Genoa.
Bring your curiosity for today’s adventure around Genoa. Some of the village’s most loved attractions await. Parrocchia Di S. Giovanni Battista is the perfect place to start. This church is one of the most curiosity-inducing places to visit in Genoa. Next, head to Cinque Terre National Park, a notable national park, known for its eye-catching features.
In between the sights, don’t hesitate to take small detours to explore local stores and eateries. When you’re ready to continue your adventure, head to Manarola Overlook Viewpoint. This romantic observation deck offers a unique experience that is highly recommended. Meanwhile, Riomaggiore adds its own distinct charm to your journey.
When you’re done exploring for the day, you’ll return to Genoa and your accommodation.
As dinnertime approaches, it's time to head out for a bite to eat in Genoa. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.
Have a fantastic dining experience at Osteria Sant'Ilario, a highly recommended choice for tonight's dinner. If you're looking to mix things up, La Cialtroneria offers an enticing alternative with its varied menu. Additionally, Manhattan Bar is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Genoa.
Savor another day of unforgettable experiences in Italy!
Day 4
- Genoa
- Florence
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Drive 259 km, 3 hours 46 min
- Leaning Tower of Pisa
- Piazza del Duomo, Pisa
- Galleria dell'Accademia
- David
- Cathedral of Santa Maria del Fiore
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On day 4 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Pisa and Florence. In the evening, you’ll end up in Florence, where you will stay for 3 nights.
Whether you prefer a leisurely exploration or a more fast-paced adventure, this itinerary in Genoa allows for both. Start by heading to Leaning Tower Of Pisa. This world-famous monument provides an insightful glimpse into the city's identity. Next, discover Piazza Del Duomo, Pisa, a majestic public square, promising a delightful encounter.
Continue your sightseeing with a visit to Galleria Dell'accademia, an interesting art gallery. When you’re done, don’t forget to make a stop at the notable David. Round off your day at Cathedral Of Santa Maria Del Fiore, another gem in Genoa with enchanting features to discover.
When you’re done exploring for the day, you’ll drive to your hotel in Florence. Check in and spend some time relaxing before you head out to tour the city.
After a day of adventure, treat yourself to an exquisite dinner at one of Florence's best restaurants.
Treat yourself to a delightful dinner at Ristorante Oliviero 1962, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Di Poneta Novoli? It's another excellent option with a diverse menu. Consider reserving a table at Caffe San Firenze as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Florence.
Explore the vibrant nightlife at Manifattura after your meal, a hub for lively evenings and memorable moments. Or, head to Se·sto On Arno Rooftop Bar for a great selection of flavorful drinks and a charming setting. Furthermore, Il Vinile is perfect for those looking to extend their night with a touch of local flavor.
Take some time to reflect on your day and savor another beautiful night in Italy.
Day 5
- Florence
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Drive 16 km, 1 hour 52 min
- The Boboli Gardens
- Ponte Vecchio
- Uffizi Gallery
- piazza della Signoria
- Basilica of Santa Croce in Florence
- Central Market
- piazzale Michelangelo
- Oltrarno
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On day 5 of your road trip, you will have an entire day to explore Florence. You’ll stay in Florence for 2 nights and discover all the best things to see and do in the area.
A visit to Oltrarno in Florence is a must on your agenda today. This neighborhood is full of hidden gems and character, perfect for a leisurely stroll. Plus, you’ll be close to some of the city’s most famous sights.
Florence is brimming with adventures. Today’s wonderful stops include a botanical garden, a historical landmark, an art gallery, a public square, a church, a food market, an observation deck and much more! Begin your sightseeing adventure at the well-known The Boboli Gardens. Just a short distance away is Ponte Vecchio, a visually striking historical landmark that draws visitors from far and near.
Continue your journey to Uffizi Gallery, one of the city’s most top-rated spots that you shouldn’t miss. Another great site to visit is the widely recognized Piazza Della Signoria. Last up on today’s itinerary is a church. Make your way to Basilica Of Santa Croce In Florence for some final sightseeing. Each attraction will leave you with lasting memories and a deeper appreciation for the rich heritage of Florence.
Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.
As dinnertime approaches, it's time to head out for a bite to eat in Florence. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.
Treat yourself to a wonderful meal at Ditta Artigianale, a top-rated dining spot in Florence. If you're in the mood for something new, try Trattoria Da Burde, another premier location with a delectable menu. You might also want to book a table at Casa Toscana. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Florence.
Keep the evening going at Bar 50 Rosso, a great choice for enjoying the after-dinner hours with a drink. You could also go to Bitter Bar, which offers a similarly pleasant setting and great drinks. Another option is Archea Brewery, which provides an inviting environment for unwinding after a busy day out.
Say good night to Florence and look forward to another great day of your road trip in Italy!
Day 6
- Florence
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Drive 158 km, 2 hours 48 min
- Porta Romana
- Pubblico Palace
- piazza del Campo
- Siena Cathedral
- Basilica of San Domenico
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Greet day 6 of your road trip in Italy with a smile and start your day with a hearty breakfast. You will return to Florence for your remaining 1 night in the city later today, but first, it’s time for some exploring! On the agenda for this day, you’ll find only the best things to see and do in Siena.
Brace yourself for today’s incredible lineup of attractions in Florence, featuring fun adventures, breathtaking views, and photo-friendly spots. Start at Porta Romana, an up-and-coming monument in the city. Then, head to Pubblico Palace and soak in the ambiance of this historic palace.
There are many interesting places to see in Florence and when you are ready for more, go to Piazza Del Campo. This is one of the city’s most impressive spots. After exploring the public square, visit the popular Siena Cathedral. Before wrapping up your self-guided sightseeing tour, head to the curiosity-inducing Basilica Of San Domenico, a curiosity-inducing church in the city.
When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Florence.
Indulge in a memorable dining experience at one of Florence's most popular restaurants, and connect with friendly locals for an authentic adventure.
Make sure to reserve a table at Ristorante Buca Mario, an iconic dining spot in Florence. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Agricola Toscana, a popular restaurant in Florence. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Eataly Firenze, a hidden gem nestled in Florence. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.
To truly maximize your evening out, consider visiting Gosh* after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to Antico Caffè Del Moro - Art Bar Firenze, another bar with an inviting ambiance. Similarly, Quelo Bar also offers a great atmosphere, ensuring a night filled with enjoyment and relaxation.
Say good night to Florence and look forward to another great day of your road trip in Italy!
Day 7
- Florence
- Rome
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Drive 366 km, 5 hours 8 min
- Basilica of San Francesco d'Assisi
- Piazza del Comune
- Basilica di Santa Chiara
- Rocca Maggiore
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Dive into day 7 of your remarkable road trip in Italy. Today you will explore Santa Maria degli Angeli, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Rome. You’ll stay here for 3 nights.
Get ready for a day filled with fun adventures, breathtaking views, and photo-friendly spots in the charming town of Florence. Your adventure starts at Basilica Of San Francesco D'assisi, a well-known local hot spot. Another notable attraction to explore is Piazza Del Comune. This locally appreciated public square is known for its breathtaking appeal.
After soaking in the highlights of these sights, take some time to wander Florence's streets and immerse yourself in the local atmosphere. When you're ready to continue your sightseeing adventure, head to Basilica Di Santa Chiara. This respected church offers a fascinating experience that many visitors find memorable. Rocca Maggiore is also worth visiting.
After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Rome. Rome offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.
After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Rome. Enjoy a satisfying meal that will recharge you for tonight's adventures.
Enjoy a lovely meal at La Bottega Roma, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Pasta In Corso is another top choice with a popular menu. You could also check for a table at Trattoria Vecchia Roma. As an establishment that gains consistently high praises from customers, it’s an ideal choice in Rome tonight.
If you’re not ready to end the night just yet, La Botticella Of Poggi Giovanni offers a perfect venue to relax and savor a drink. Similarly, Almalu Trastevere is well-suited for those looking to unwind in a social setting. Bar Viminale Di Pepi Maurilio is another excellent spot to enjoy a nightcap after a delightful meal.
Relax and reminisce about your day in Italy and look forward to more memorable moments to come!
Day 8
- Rome
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Drive 13 km, 1 hour 50 min
- Colosseum
- Roman Forum
- Pantheon
- Piazza Navona
- Castel Sant'Angelo
- Altare della Patria
- Trevi Fountain
- Piazza di Spagna
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Day 8 of your road trip across Italy promises a magnificent time exploring Rome. You have 2 nights left in Rome. Take the opportunity to experience more of the best attractions and activities in the city.
Immerse yourself in Rome’s rich culture with today's sightseeing itinerary. Start your journey at Colosseum. This UNESCO world heritage-designated archeological site is sure to ignite your curiosity. Next, dive into the picture-perfect features of Roman Forum, a must-visit archeological site in the city.
In between sights, stop by local stores, picturesque photo spots, and small eateries. When you’re ready for your next attraction, proceed to Pantheon, a world-famous monument. For a change of scene, check out Piazza Navona, known for its noteworthy features.
Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.
As you explore more of Rome, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.
Savor the flavors at RomAntica, a top pick for dinner tonight. Alternatively, Coso Ristorante beckons with its unique menu offerings. Also, consider DEROMA - Farine Romane. With its consistent customer satisfaction, it’s an excellent option for dining in Rome tonight.
Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, Sant' Eustachio Caffè stands out as an excellent choice for a post-dinner cocktail. Alternatively, Yellowsquare Rome offers an ideal atmosphere to enjoy the pleasures of the night. Caffè Portofino is also a great option that provides a perfect setting for a relaxing evening.
Celebrate another amazing day of your road trip adventure in Italy!
Day 9
- Rome
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Drive 15 km, 58 min
- Vatican Museums
- Sistine Chapel
- St Peter's Basilica
- piazza del Popolo
- Trastevere
- Via del Corso
- Via dei Condotti
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On day 9 of your road trip in Italy, you’ll start and end your day in Rome, but spend the day exploring what’s beyond the city. Since you will return to Rome for 1 night more, there’s no need to rush. Experience Vatican City and Rome to the fullest today with this curated day itinerary!
Make sure to visit Trastevere, a popular neighborhood in Vatican City. Spend some time wandering around the area and soak in its distinctive charm. You’ll also discover that several of the city’s must-see attractions are just around the corner.
Today’s well-planned self-sightseeing route offers several fun adventures, romantic experiences, and scenic views. Whether you decide to explore Rome on foot, use public transport, or join a guided tour, there are a few attractions you don’t want to miss. Vatican Museums is the first of them. Sistine Chapel is your next stop. This top-rated chapel is one of the best-rated sights in Rome.
Consider grabbing some lunch or a light snack to keep your energy going. Beyond the above-mentioned attractions, today is also the perfect time to visit St. Peter's Basilica. To round off your sightseeing experience, visit Piazza Del Popolo.
When you’re done exploring for the day, you’ll return to Rome and your accommodation.
After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Rome. Enjoy a satisfying meal that will recharge you for tonight's adventures.
Don’t miss out on dining at Hotel de Russie, a top-rated dining destination in Rome. If you're in the mood to try something new, consider La Taverna Italiana, another top spot with a mouthwatering menu. You might also want to secure a reservation at The Parrot Bar. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Rome this evening.
Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, The Apartment Bar Roma stands out as an excellent choice for a post-dinner cocktail. Alternatively, Hotel Hassler Roma offers an ideal atmosphere to enjoy the pleasures of the night.
As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in Italy.
Day 10
- Rome
- Genoa
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Drive 520 km, 6 hours 1 min
- Orvieto Cathedral
- Orvieto subterranea
- Pozzo della Cava
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On day 10 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, Orvieto. When you’re not sightseeing, take time to relax at your selected hotel in Genoa, where you’ll be staying for 1 night.
Get ready to discover some of the most iconic wonders in Rome, including a church, a cave system, and a cave. Start your day at Orvieto Cathedral. This symbolic church is an interesting place to see in Rome. Then, wander over to Orvieto Underground. If heritage-rich sites excite you, this cave system will be right up your alley. Nearby, you’ll also find Pozzo Della Cava. This history-steeped cave is a favorite among visitors.
At the end of the day, you will drive to Genoa, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.
As dinnertime approaches, it's time to head out for a bite to eat in Genoa. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.
Enjoy a lovely dining experience at Vivarelli, a popular restaurant in Genoa. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Genoa at Trattoria Ugo, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated TAZZE PAZZE Specialty Coffee. It’s yet another ideal choice to enhance your time in Genoa tonight.
Celebrate another amazing day of your road trip adventure in Italy!
Day 11
- Genoa - Departure day
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- Piazza della Vittoria
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Day 11 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Genoa before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.
If you're up for some more sightseeing, begin at Piazza Della Vittoria. This intriguing public square is a popular place to see in the city.
Explore local shops for souvenirs to remember your trip or find unique gifts for loved ones. Discover boutiques offering an array of stylish fashion choices.
Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Genoa.
Dine in style at Bar Festival, a top recommendation for dinner tonight. Or, for a change of pace, Il Marin boasts a menu that's sure to impress.
You’ll then say farewell to Genoa. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!
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