11-Day Italy Self-Drive Road Trip With Itinerary from Genoa to Florence and Rome
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Escape the ordinary with this exciting 11-day road trip through Italy. Explore the diverse landscapes, lively cities, and beyond. Pack your bags, hit the road, and prepare for an unforgettable journey!
This perfectly planned road trip itinerary in Italy takes you through some of the best places to see in the country. You will spend 4 nights in Genoa, 3 nights in Florence, and 3 nights in Rome. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!
With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.
Upon arriving in Genoa, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.
An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Trevi Fountain and Colosseum are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Pantheon, learn more about the unique Piazza Navona, and immerse yourself in the vibrant atmosphere of St. Peter's Basilica.
As you hit the open road and drive through Genoa, Riomaggiore, Manarola, Corniglia, Vernazza, Pisa, Florence, Siena, Santa Maria degli Angeli, Rome, and Orvieto, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.
Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.
This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.
The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!
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Day 1
- Genoa - Arrival day
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- Aquarium of Genoa
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Say hello to Genoa! Your exciting road trip through Italy is just about to start. Navigating the top places to see in the region is a breeze with a car. The rental vehicle of your choice will be ready for pickup upon your arrival in the city. You will stay in Genoa for 3 nights before you continue your adventure!
Genoa is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Aquarium Of Genoa, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.
Make your way to your chosen hotel. Check-in typically starts between 2 and 4 PM in Genoa. Make yourself at home and enjoy some downtime before heading out again.
As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Genoa, it's often a good idea to reserve a table in advance.
Treat yourself to a delicious dinner at 7 Sensi cucina decontaminata, an excellent option for tonight's dining. Looking for something different? Alla Lunga Ristorante offers a tantalizing alternative with its diverse menu. And don’t miss Grand Hotel Savoia. With its reputation for pleasing customers, it’s a fantastic choice for tonight in Genoa.
Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, Scurreria Beer & Bagel stands out as an excellent choice for a post-dinner cocktail. Alternatively, La Lepre offers an ideal atmosphere to enjoy the pleasures of the night. Bar Pisacane Iii is also a great option that provides a perfect setting for a relaxing evening.
Raise a toast to the start of your 11-day road trip in Italy!
Day 2
- Genoa
- More
Drive 20 km, 1 hour 18 min
- AMT GENOVA - Ferrovia Genova Casella
- Royal Palace Museum
- Strada Nuova Museums - Palazzo Rosso
- Via Garibaldi
- Palazzo Podestà
- Lighthouse of Genoa
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Day 2 of your road trip will take you to the best attractions Genoa has to offer. Cherish the 2 nights you have left in Genoa by discovering the best things there are to see and do in the city.
Get ready to discover some of the most iconic wonders in Genoa, including a heritage railway, a museum, a street, a palace, a lighthouse and much more! Start your day at Amt Genova - Ferrovia Genova Casella. This instagrammable heritage railway is a worthwhile place to see in Genoa. Then, wander over to Royal Palace Museum. If instagrammable sites excite you, this museum will be right up your alley. Nearby, you’ll also find Strada Nuova Museums - Palazzo Rosso. This instagrammable museum is a favorite among visitors.
Genoa offers plenty to explore, ensuring every moment of your visit is filled with excitement and discovery. If you're up for more, Via Garibaldi is a curiosity-inducing spot in the city that will captivate you with its unique charm. When you’re done at the street, don’t forget to check out the historic Palazzo Podestà. Take a moment to appreciate the fascinating details of this often recommended palace. Wrap up your self-guided tour of Genoa's top attractions with a visit to Lighthouse Of Genoa.
Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.
After a day of adventure, treat yourself to an exquisite dinner at one of Genoa's best restaurants.
Dine in style at Zeffirino, a top recommendation for dinner tonight. Or, for a change of pace, Trattoria Vegia Zena boasts a menu that's sure to impress. Also, be sure to check out Trattoria delle Grazie. Known as a local hotspot, it’s a great choice for tonight in Genoa.
Celebrate another amazing day of your road trip adventure in Italy!
Day 3
- Genoa
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Drive 245 km, 4 hours 46 min
- Riomaggiore
- Manarola Overlook Viewpoint
- Cinque Terre National Park
- Ruins of Doria Tower
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On day 3 of your road trip in Italy, you’ll start and end your day in Genoa, but spend the day exploring what’s beyond the city. Since you will return to Genoa for 1 night more, there’s no need to rush. Experience Riomaggiore, Manarola, Corniglia, and Vernazza to the fullest today with this curated day itinerary!
Enjoy the perfect balance of relaxation and exploration in Genoa today. One of the most worthwhile attractions included on the itinerary is Riomaggiore. Then, take a leisurely stroll to Manarola Overlook Viewpoint and learn what makes this eye-catching observation deck unique.
Throughout the day, make sure to take breaks to appreciate the surroundings. Next up, visit the notable Cinque Terre National Park. After exploring the national park, head to Ruins Of Doria Tower. This locally appreciated monument is a highlight in Genoa.
When you’re done exploring for the day, you’ll return to Genoa and your accommodation.
As dinnertime approaches, it's time to head out for a bite to eat in Genoa. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.
Make sure to reserve a table at Osteria Sant'Ilario, an iconic dining spot in Genoa. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of La Cialtroneria, a popular restaurant in Genoa. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Manhattan Bar, a hidden gem nestled in Genoa. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.
Savor another day of unforgettable experiences in Italy!
Day 4
- Genoa
- Florence
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Drive 259 km, 3 hours 47 min
- Leaning Tower of Pisa
- Piazza del Duomo, Pisa
- Porta Nuova
- Galleria dell'Accademia
- Cathedral of Santa Maria del Fiore
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Embark on another extraordinary experience on day 4 of your road trip in Italy. Today, you will make 2 stops and experience some of the highlights of Pisa and Florence. At the end of the day, you will enjoy the comforts of a top-rated hotel in Florence, which will be your home away from home for 3 nights.
Today's adventure in Genoa promises more breathtaking discoveries and enriching experiences! Begin at Leaning Tower Of Pisa. This UNESCO world heritage-designated monument is a highlight of any visit in the city. Then, enjoy Piazza Del Duomo, Pisa, another historic attraction that never fails to captivate visitors. Next, head over to Porta Nuova, one of the city’s most often recommended attractions, known for its symbolic features.
If you’re looking for more, spend time soaking in the atmosphere of Galleria Dell'accademia. This instagrammable art gallery is frequented by locals and tourists alike. To complete your memorable day, make sure to visit Cathedral Of Santa Maria Del Fiore, an extraordinary church, and take a stroll around the area.
At the end of the day, you will drive to Florence, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.
After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Florence. Enjoy a satisfying meal that will recharge you for tonight's adventures.
Savor the flavors at Ristorante Oliviero 1962, a top pick for dinner tonight. Alternatively, Di Poneta Novoli beckons with its unique menu offerings. Also, consider Caffe San Firenze. With its consistent customer satisfaction, it’s an excellent option for dining in Florence tonight.
Let the evening flow smoothly from dinner to drinks at Manifattura, a top-rated bar in the area. For other recommendations, Se·sto On Arno Rooftop Bar provides a perfect setting for rounding out your night with style and great drinks. Likewise, Il Vinile offers a memorable night with diverse drink options and excellent service.
Head back to your accommodation in Florence and get some rest in preparation for another magical day of your road trip in Italy!
Day 5
- Florence
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Drive 7 km, 53 min
- Ponte Vecchio
- Uffizi Gallery
- Palazzo Vecchio
- piazza della Signoria
- Basilica of Santa Croce in Florence
- piazzale Michelangelo
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On day 5 of your road trip, you will have an entire day to explore Florence. You’ll stay in Florence for 2 nights and discover all the best things to see and do in the area.
Start by visiting Ponte Vecchio, a prime spot to begin your journey. This romantic historical landmark is sure to impress. Next on your list is Uffizi Gallery, another must-visit landmark and famous art gallery renowned for its romantic features.
While exploring and sightseeing, take time to savor the culture of Florence by sampling some local delicacies. When you’re ready for more sightseeing, head to Palazzo Vecchio. This visually striking palace is an essential place to visit for anyone looking for the full Florence experience. We also recommend visiting Piazza Della Signoria, a widely recognized public square. Nearby, you'll also find Basilica Of Santa Croce In Florence, ready to add charm to your journey. End your self-guided sightseeing tour with a stop at Piazzale Michelangelo and wrap up your day with its majestic appeal.
Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.
As you explore more of Florence, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.
Treat yourself to a delicious dinner at Ditta Artigianale, an excellent option for tonight's dining. Looking for something different? Trattoria Da Burde offers a tantalizing alternative with its diverse menu. And don’t miss Casa Toscana. With its reputation for pleasing customers, it’s a fantastic choice for tonight in Florence.
Extend your evening after a delightful meal by visiting Bar 50 Rosso, which offers the perfect atmosphere for a night out. Moreover, Bitter Bar is another popular option for a drink or two. Likewise, Archea Brewery also provides a great ambiance for reminiscing about the day and raising a toast to your vacation.
Raise your glass and celebrate another amazing day of your road trip in Italy!
Day 6
- Florence
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Drive 156 km, 3 hours 2 min
- Pubblico Palace
- Tower of Mangia
- piazza del Campo
- Siena Cathedral
- Basilica of San Domenico
- Fortezza Medicea
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Greet day 6 of your road trip in Italy with a smile and start your day with a hearty breakfast. You will return to Florence for your remaining 1 night in the city later today, but first, it’s time for some exploring! On the agenda for this day, you’ll find only the best things to see and do in Siena.
Bring your curiosity for today’s adventure around Florence. Some of the city’s most loved attractions await! Pubblico Palace is the perfect place to start. This palace is one of the most worthwhile places to visit in Florence. Next, head to Tower Of Mangia, a locally appreciated monument, known for its breathtaking features.
In between the sights, don’t hesitate to take small detours to explore local stores and eateries. When you’re ready to continue your adventure, head to Piazza Del Campo. This visually striking public square is a highly recommended experience. Nearby, you'll also find Siena Cathedral and Basilica Of San Domenico. Visit these for an interesting touch to your journey. Finish the day with a visit to Fortezza Medicea (siena), a breathtaking monument in Florence.
When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Florence.
After a day of adventure, treat yourself to an exquisite dinner at one of Florence's best restaurants.
Enjoy a delicious meal at Ristorante Buca Mario, a highly-rated dining destination in Florence. If you're eager to try something different, consider Agricola Toscana, another top spot with a tantalizing menu. You might also want to secure a reservation at Eataly Firenze. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Florence this evening.
Continue your evening by exploring the vibrant nightlife scene at Gosh*, a prime destination for a thrilling night out. Also, don’t forget to check out Antico Caffè Del Moro - Art Bar Firenze, a bar that offers unique local touches. Likewise, Quelo Bar provides an excellent alternative for a fun evening.
Relax and reminisce about your day in Italy and look forward to more memorable moments to come!
Day 7
- Florence
- Rome
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Drive 366 km, 5 hours 8 min
- Basilica of San Francesco d'Assisi
- Piazza del Comune
- Basilica di Santa Chiara
- Rocca Maggiore
- More
Experience an unparalleled adventure on day 7 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 vibrant destinations - Santa Maria degli Angeli. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Rome. You will spend 3 nights here for some well-deserved relaxation.
Bring your curiosity for today’s adventure around Florence. Some of the town’s most loved attractions await! Basilica Of San Francesco D'assisi is the perfect place to start. This church is one of the most locally renowned places to visit in Florence. Next, head to Piazza Del Comune, a beloved public square, known for its UNESCO world heritage-listed features.
In between the sights, don’t hesitate to take small detours to explore local stores and eateries. When you’re ready to continue your adventure, head to Basilica Di Santa Chiara. This stunning church is a highly recommended experience. Nearby, you'll also find Rocca Maggiore. Visit these for an interesting touch to your journey.
When you’re done exploring for the day, you’ll drive to your hotel in Rome. Check in and spend some time relaxing before you head out to tour the city.
As you explore more of Rome, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.
Treat yourself to a wonderful meal at La Bottega Roma, a top-rated dining spot in Rome. If you're in the mood for something new, try Pasta In Corso, another premier location with a delectable menu. You might also want to book a table at Trattoria Vecchia Roma. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Rome.
Unwind after your meal by stepping into La Botticella Of Poggi Giovanni. This venue is celebrated for its extensive drink selections and cozy vibes. Alternatively, Almalu Trastevere offers a dynamic and energetic atmosphere for a glass or two. Don’t overlook Bar Viminale Di Pepi Maurilio, another top-rated bar in the area.
As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in Italy.
Day 8
- Rome
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Drive 9 km, 1 hour 17 min
- Colosseum
- Roman Forum
- Trevi Fountain
- Pantheon
- Piazza Navona
- Castel Sant'Angelo
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Day 8 offers a multitude of experiences. You will stay in Rome for 2 nights more, offering you enough time to explore at a relaxed pace.
Today’s agenda in Rome includes an archeological site, a monument, a public square, a castle and much more! Colosseum is must-visit archeological site and a great starting point for the day. Next, continue your journey to Roman Forum, a globally renowned archeological site, located just a leisurely stroll away. Next, head to Trevi Fountain, a detailed monument, also available for your discovery today.
Each stop on today’s itinerary promises to leave you with lasting memories and a deeper appreciation for Rome. When you're ready, let your sightseeing route take you to the world-famous Pantheon. If you’re looking for more, Piazza Navona is also a globally renowned attraction that is worthwhile a visit. Lastly, don’t miss Castel Sant'angelo, a place of enchanting interest in the city.
Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.
After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Rome. Enjoy a satisfying meal that will recharge you for tonight's adventures.
Treat yourself to a delightful dinner at RomAntica, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Coso Ristorante? It's another excellent option with a diverse menu. Consider reserving a table at DEROMA - Farine Romane as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Rome.
Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, Sant' Eustachio Caffè stands out as an excellent choice for a post-dinner cocktail. Alternatively, Yellowsquare Rome offers an ideal atmosphere to enjoy the pleasures of the night. Caffè Portofino is also a great option that provides a perfect setting for a relaxing evening.
Head back to your accommodation in Rome and get some rest in preparation for another magical day of your road trip in Italy!
Day 9
- Rome
- More
Drive 12 km, 1 hour
- St Peter's Basilica
- Sistine Chapel
- Vatican Museums
- Piazza di Spagna
- Trastevere
- Via dei Condotti
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Wake up to day 9 of your extraordinary road trip in Italy. With 1 night left in Rome, we encourage you to seize the day and discover the unexplored beauty of the city’s surroundings!
Set aside time today to explore Trastevere, a standout neighborhood that reflects the essence of the city. While you're there, you'll also be within reach of some of the city's top landmarks, making it easy to maximize your day. You might also want to visit Via dei Condotti, a street offering another perspective on the city.
Start your adventure at St. Peter's Basilica. This wondrous major basilica is a place that is appreciated by travelers and locals alike.
Consider stopping for a small bite to eat or a drink at a local eatery to keep your energy going. When you’re ready, continue your discovery with a visit to Vatican Museums. This iconic art museum offers an enriching experience. For a change of pace, head to Piazza Di Spagna, where you can take in visually striking features. These sights offer a fulfilling end to a perfect day.
When you’re done exploring for the day, you’ll return to Rome and your accommodation.
After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Rome. Enjoy a satisfying meal that will recharge you for tonight's adventures.
Dine in style at Hotel de Russie, a top recommendation for dinner tonight. Or, for a change of pace, La Taverna Italiana boasts a menu that's sure to impress. Also, be sure to check out The Parrot Bar. Known as a local hotspot, it’s a great choice for tonight in Rome.
Continue the enjoyment post-dinner at The Apartment Bar Roma, a cherished local gathering spot renowned for its welcoming atmosphere. Similarly, Hotel Hassler Roma offers a vibrant space for indulging in well-crafted drinks and engaging conversation.
Head back to your accommodation in Rome and get some rest in preparation for another magical day of your road trip in Italy!
Day 10
- Rome
- Genoa
- More
Drive 519 km, 6 hours 15 min
- Well of St Patrick
- Orvieto Cathedral
- Orvieto subterranea
- Torre del Moro Orvieto
- Pozzo della Cava
- More
Dive into day 10 of your remarkable road trip in Italy. Today you will explore Orvieto, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Genoa. You’ll stay here for 1 night.
Prepare for a day full of family-friendly attractions, breathtaking views, and picturesque spots. When you’re ready, kick off your sightseeing adventure at Well Of St. Patrick. This popular monument is a must-visit for anyone seeking a unique vacation experience. Another sight you shouldn’t miss is Orvieto Cathedral, one of the village’s best highlights.
Next, check out Orvieto Underground, one of the most beloved places to see in Rome. This cave system is a favorite among locals and travelers alike. Enjoy some downtime and refreshments before continuing to your next stop, Torre Del Moro Orvieto. Wander around and soak in the historic atmosphere this monument offers. Then, head to Pozzo Della Cava, a top-rated cave that adds another dimension to your day.
After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Genoa. Genoa offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.
As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Genoa. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.
Treat yourself to a delightful dinner at Vivarelli, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Trattoria Ugo? It's another excellent option with a diverse menu. Consider reserving a table at TAZZE PAZZE Specialty Coffee as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Genoa.
Relax and recharge in preparation for another adventurous day in Italy!
Day 11
- Genoa - Departure day
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- piazza De Ferrari
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Day 11 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Genoa before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.
If you're up for some more sightseeing, we recommend visiting Piazza De Ferrari, an enchanting public square before you head out.
As your final day in Italy unfolds, enjoy a last-minute shopping spree in Genoa's best shopping area, Via Garibaldi. Enjoy finding the perfect gift or keepsake to remind you of your wonderful trip to Italy. Browse through boutiques to find unique and stylish fashion pieces to take home.
Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Genoa.
Savor the flavors at Bar Festival, a top pick for dinner tonight. Alternatively, Il Marin beckons with its unique menu offerings.
You’ll then say farewell to Genoa. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!
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