11-Day Italy Self-Drive Road Trip With Itinerary from Naples traveling north to Viterbo, Florence, Siena, and Rome

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Explore the best of Italy on a 11-day road trip! Uncover hidden gems and experience the rich culture firsthand as you journey through Naples, Tivoli, Viterbo, Florence, Pisa, Siena, and Rome. This road trip itinerary in Italy seamlessly combines exploration with relaxation.

This perfectly planned road trip itinerary in Italy takes you through some of the best places to see in the country. You will spend 3 nights in Naples, 1 night in Viterbo, 3 nights in Florence, 1 night in Siena, and 2 nights in Rome. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Naples, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Trevi Fountain and Colosseum are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Pantheon, learn more about the unique Piazza Navona, and immerse yourself in the vibrant atmosphere of St. Peter's Basilica.

As you hit the open road and drive through Naples, Tivoli, Viterbo, Florence, Pisa, Siena, and Rome, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.

Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!

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Driver’s age is 30 - 65
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Itinerary summary

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Days
Destination
Attractions
Overnight
Day
City & Overnight
Attractions
Ovo Castle
Cappella SanseveroNaples National Archaeological MuseumCastel Sant'ElmoChiaia
piazza del PlebiscitoCattedrale di Santa Maria AssuntaVilla d'EsteFontana dell'Ovato (o di Tivoli)
Piazza del PlebiscitoPalazzo dei Papi di ViterboTerme dei papiTherma OasiThe Bagnaccio, spa park and botanical garden
Ponte VecchioUffizi Gallerypiazza della SignoriaBasilica of Santa Croce in FlorenceOltrarno
Central MarketCathedral of Santa Maria del FioreGalleria dell'AccademiaDavidpiazzale Michelangelo

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Day 1

Day 1

  • Naples - Arrival day
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  • Ovo Castle
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Welcome to Naples, the perfect starting point for your road trip in Italy! Pick up your rental car and let the adventure begin. You will spend 2 nights immersing yourself in Naples's charm before embarking on the next leg of your journey.

Naples is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Ovo Castle, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

As afternoon approaches, head to your chosen hotel in Naples. Check-in typically starts around 2 to 4 PM at hotels in Italy. We recommend staying at a hotel in a central location for easy access to the best attractions, restaurants, and bars in the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Naples, it's often a good idea to reserve a table in advance.

Make sure to reserve a table at L'Oca Nera Irish Pub, an iconic dining spot in Naples. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Mimì alla Ferrovia, a popular restaurant in Naples. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Spuzzulè Winebar, a hidden gem nestled in Naples. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at Happening Cocktail Bar, a well-loved spot among locals and tourists. Or, head to Shanti Art Musik Bar. This bar boasts a welcoming environment that is perfect for winding down. You could also continue your night at Gran Caffè Gambrinus, another top-rated place in the area.

Raise a toast to the start of your 11-day road trip in Italy!

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Day 2

Day 2

  • Naples
  • More

Drive 12 km, 1 hour 7 min

  • Cappella Sansevero
  • Naples National Archaeological Museum
  • Castel Sant'Elmo
  • Chiaia
  • More

Day 2 of your road trip across Italy promises a magnificent time exploring Naples. You have 1 night left in Naples. Take the opportunity to experience more of the best attractions and activities in the city.

Set aside time today to explore Chiaia, a standout neighborhood that reflects the essence of the city. While you're there, you'll also be within reach of some of the city's top landmarks, making it easy to maximize your day.

Brace yourself for today’s incredible lineup of attractions in Naples, featuring family-friendly attractions, picturesque spots, and historic treasures. Start at Cappella Sansevero, a locally renowned museum in the city. Then, head to Naples National Archaeological Museum and soak in the ambiance of this noteworthy museum.

There are many interesting places to see in Naples, and when you are ready for more, go to Castel Sant'elmo. This is one of the city’s most well-known breathtaking spots of interest.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

Bring home unique finds from Naples's bustling shopping hub, Via Toledo. Enjoy a leisurely exploration of unique stores where locals shop. Don’t forget to browse souvenirs and local specialties that make perfect gifts for your loved ones. Beyond shopping, Via Toledo offers plenty of options, including primary services, unique landmarks, and community events.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Naples. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Discover the culinary delights of Naples by securing a reservation at Veritas. Esteemed for its 1-star Guide Michelin recognition, this restaurant offers a remarkable selection of campanian and contemporary cuisine. For an alternative dining experience, try Il Comandante, renowned for its delicious creative and mediterranean dishes. This esteemed 1-star Michelin-recipient consistently impresses guests, making it a must-visit spot during your holiday. Craving more culinary excitement? Head to ARIA, a highly recommended local eatery celebrated for its mouthwatering contemporary and modern menu. With its 1-star Michelin recognition, it offers an unforgettable dining adventure.

Continue your lively evening at Archivio Storico - Cocktail Bar & Wonderfood, a perfect place for winding down or revving up the night, depending on which mood you’re in. Archeobar is another excellent bar that offers a great selection of drinks to suit any mood. If you prefer to go somewhere else, Babette Pub ensures a night out tailored to your taste.

Head back to your accommodation in Naples and get some rest in preparation for another magical day of your road trip in Italy!

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Day 3

Day 3

  • Naples
  • Viterbo
  • More

Drive 326 km, 3 hours 58 min

  • piazza del Plebiscito
  • Cattedrale di Santa Maria Assunta
  • Villa d'Este
  • Fontana dell'Ovato (o di Tivoli)
  • More

Dive into day 3 of your remarkable road trip in Italy. Today you will explore Naples and Tivoli, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Viterbo. You’ll stay here for 1 night.

Immerse yourself in Naples’s rich culture with today's sightseeing itinerary. Start your journey at Piazza Del Plebiscito. This history-steeped public square is sure to ignite your curiosity. Next, dive into the stunning features of Cattedrale Di Santa Maria Assunta, a must-visit church in the city.

In between sights, stop by local stores, picturesque photo spots, and small eateries. When you’re ready for your next attraction, proceed to Villa D'este, a well-known palace. For a change of scene, check out Fontana Dell'ovato (o Di Tivoli), known for its history-steeped features.

When you’re done exploring for the day, you’ll drive to your hotel in Viterbo. Check in and spend some time relaxing before you head out to tour the city.

Indulge in a memorable dining experience at one of Viterbo's most popular restaurants, and connect with friendly locals for an authentic adventure.

Relax and recharge in preparation for another adventurous day in Italy!

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Day 4

Day 4

  • Viterbo
  • Florence
  • More

Drive 228 km, 3 hours 20 min

  • Piazza del Plebiscito
  • Palazzo dei Papi di Viterbo
  • Terme dei papi
  • Therma Oasi
  • The Bagnaccio, spa park and botanical garden
  • More

Embark on another extraordinary experience on day 4 of your road trip in Italy. Today, you will make 1 stop and experience some of the highlights of Viterbo. At the end of the day, you will enjoy the comforts of a top-rated hotel in Florence, which will be your home away from home for 3 nights.

A blend of fun adventures, romantic experiences, and picturesque spots await you in Viterbo on today’s itinerary. First up is the underrated public square, Piazza Del Plebiscito. Afterward, continue to Palazzo Dei Papi Di Viterbo, a palace every traveler should visit.

As you explore Viterbo’s charming streets, take in the lively atmosphere and get to know the character of the city. Next, make your way to Terme Dei Papi. This increasingly popular spa is an essential stop. Following that, head to Therma Oasi, another must-visit site that will enhance your experience. Don’t forget to stop by The Bagnaccio, Spa Park And Botanical Garden, a worthwhile spa in the city.

At the end of the day, you will drive to Florence, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a day of adventure, treat yourself to an exquisite dinner at one of Florence's best restaurants.

Enjoy an outstanding dining experience at Enoteca Pinchiorri, a 3-star Michelin restaurant offering an exceptional italian contemporary menu. Alternatively, if you're in the mood for something different, consider the nearby 2-star Michelin-awardee, Santa Elisabetta, known for its delicious creative and mediterranean cuisine. Another highly-recommended place to eat in Florence is Gucci Osteria da Massimo Bottura, a renowned restaurant with a 1-star Guide Michelin recognition and a delicious italian contemporary and international menu.

Keep the excitement of the evening going by visiting a bar or two. Manifattura is an excellent place to start. You could also check out Se·sto On Arno Rooftop Bar, offering a different kind of charm. A last recommendation for the day is Il Vinile. This bar promises an enjoyable experience with tasty drinks and a vibrant setting.

Take some time to reflect on your day and savor another beautiful night in Italy.

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Day 5

Day 5

  • Florence
  • More

Drive 1 km, 25 min

  • Ponte Vecchio
  • Uffizi Gallery
  • piazza della Signoria
  • Basilica of Santa Croce in Florence
  • Oltrarno
  • More

Day 5 of your road trip will take you to the best attractions Florence has to offer. Cherish the 2 nights you have left in Florence by discovering the best things there are to see and do in the city.

Don’t miss Oltrarno in Florence today, a must-see neighborhood that offers a glimpse into the city’s vibrant character. Take your time to explore its best features, and enjoy the convenience of nearby top-rated landmarks.

Florence is brimming with adventures. Today’s wonderful stops include a historical landmark, an art gallery, a public square, a church and much more! Begin your sightseeing adventure at the iconic Ponte Vecchio and allow yourself time to explore. Just a short distance away you'll find your next stop, Uffizi Gallery, a historic art gallery that draws visitors from far and near.

Continue your journey to Piazza Della Signoria, one of the city’s most extraordinary spots that you shouldn’t miss. Another great site to visit is the captivating Basilica Of Santa Croce In Florence.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

After a day of adventure, treat yourself to an exquisite dinner at one of Florence's best restaurants.

Have a fantastic dining experience at Ditta Artigianale, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Trattoria Da Burde offers an enticing alternative with its varied menu. Additionally, Casa Toscana is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Florence.

Extend your evening after a delightful meal by visiting Bar 50 Rosso, which offers the perfect atmosphere for a night out. Moreover, Bitter Bar is another popular option for a drink or two. Likewise, Archea Brewery also provides a great ambiance for reminiscing about the day and raising a toast to your vacation.

As the sun sets on another day of adventure, rest up and recharge for the next leg of your road trip in Italy.

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Day 6

Day 6

  • Florence
  • More

Drive 11 km, 57 min

  • Central Market
  • Cathedral of Santa Maria del Fiore
  • Galleria dell'Accademia
  • David
  • piazzale Michelangelo
  • More

Day 6 offers a multitude of experiences. You will stay in Florence for 1 night more, offering you enough time to explore at a relaxed pace.

Get ready for a day filled with fun adventures, photo-friendly spots, and budget-friendly activities in the charming city of Florence. Your adventure starts at Central Market, a captivating local hot spot. Another notable attraction to explore is Cathedral Of Santa Maria Del Fiore. This astonishing church is known for its instagrammable appeal.

After soaking in the highlights of these sights, take some time to wander Florence's streets and immerse yourself in the local atmosphere. When you're ready to continue your sightseeing adventure, head to Galleria Dell'accademia. This history-steeped art gallery offers a fascinating experience that many visitors find memorable. David is also worth visiting, along with Piazzale Michelangelo. These standout landmarks offer unique experiences that add to the day’s enjoyment.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

As dinnertime approaches, it's time to head out for a bite to eat in Florence. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Enjoy a lovely dining experience at Ristorante Buca Mario, a popular restaurant in Florence. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Florence at Agricola Toscana, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated Eataly Firenze. It’s yet another ideal choice to enhance your time in Florence tonight.

Round off your dining experience by visiting Gosh*, a prime location for a drink. Alternatively, explore the distinctive characteristics of Antico Caffè Del Moro - Art Bar Firenze, a bar catering to every mood and preference. Quelo Bar likewise offers a unique atmosphere, perfect for a memorable night out.

Raise your glass to another unforgettable day in Italy!

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Day 7

Day 7

  • Florence
  • Siena
  • More

Drive 213 km, 3 hours 13 min

  • Leaning Tower of Pisa
  • Angelo Caduto
  • Pisa Cathedral
  • Piazza del Duomo, Pisa
  • Campo santo
  • More

On day 7 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, Pisa. When you’re not sightseeing, take time to relax at your selected hotel in Siena, where you’ll be staying for 1 night.

Continue your journey to Pisa Cathedral, one of the city’s most intriguing spots that you shouldn’t miss. Another great site to visit is the wondrous Piazza Del Duomo, Pisa. When you're finished at the public square, Campo Santo awaits your visit. This cemetery is a picture-perfect highlight on today's itinerary.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Siena. Siena offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As dinnertime approaches, it's time to head out for a bite to eat in Siena. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Treat yourself to a delightful dinner at Enoteca I Terzi, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Ristorante Tar-Tufo? It's another excellent option with a diverse menu. Consider reserving a table at Antica Trattoria Papei as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Siena.

After your meal, keep the night alive at a bar like Meet Life Cafè, known for its lively atmosphere. Maudit Pub is another top recommendation that provides the perfect setting with well-crafted drinks and a welcoming ambiance. Similarly, Bar Impero Siena offers an excellent atmosphere for those looking to amp up the evening.

Relax and reminisce about your day in Italy and look forward to more memorable moments to come!

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Day 8

Day 8

  • Siena
  • Rome
  • More

Drive 241 km, 3 hours 23 min

  • Sistine Chapel
  • St Peter's Basilica
  • Saint Peter's Square
  • Vatican Museums
  • More

Experience an unparalleled adventure on day 8 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 vibrant destinations - Vatican City. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Rome. You will spend 2 nights here for some well-deserved relaxation.

Next, go to St. Peter's Basilica.

Vatican Museums is another noteworthy attraction worthwhile a visit.

When you’re done exploring for the day, you’ll drive to your hotel in Rome. Check in and spend some time relaxing before you head out to tour the city.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Rome. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Have a memorable dining experience in Rome by booking a table at La Pergola, renowned as a 3-star Michelin restaurant presenting an exceptional mediterranean and contemporary menu. For a different culinary experience in Rome, Il Pagliaccio shines as one of the top destinations, known for its delicious creative and innovative cuisine. This 2-star Michelin-awardee earns consistently high praises from previous guests, making it a must-visit addition to your holiday experience. If you're looking for an alternative, Enoteca La Torre is known as a top local spot for its delicious mediterranean and creative cuisine in Rome. This 2-star Michelin awardee is a highly recommended choice for an unforgettable meal.

If you’re not ready to end the night just yet, La Botticella Of Poggi Giovanni offers a perfect venue to relax and savor a drink. Similarly, Almalu Trastevere is well-suited for those looking to unwind in a social setting. Bar Viminale Di Pepi Maurilio is another excellent spot to enjoy a nightcap after a delightful meal.

Say good night to Rome and look forward to another great day of your road trip in Italy!

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Day 9

Day 9

  • Rome
  • More

Drive 5 km, 48 min

  • Piazza Navona
  • Roman Forum
  • Colosseum
  • Trastevere
  • Monti
  • More

On day 9 of your road trip, you will have an entire day to explore Rome. You’ll stay in Rome for 1 night and discover all the best things to see and do in the area.

At the top of the list of things to do today is to explore Trastevere, a neighborhood that captures the true essence of Rome. Take your time to uncover its best sides and enjoy its proximity to many of the area’s best attractions. Another must-visit is Monti, a neighborhood offering a different perspective on Rome.

Enjoy the perfect balance of relaxation and exploration in Rome today. One of the most iconic attractions included on the itinerary is Piazza Navona. This symbolic public square will help you start your sightseeing on top. Then, take a leisurely stroll to Roman Forum and learn what makes this historic archeological site unique.

Throughout the day, make sure to take breaks to appreciate the surroundings. Next up, visit the globally renowned Colosseum.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

Indulge in a memorable dining experience at one of Rome's most popular restaurants, and connect with friendly locals for an authentic adventure.

Enjoy a lovely meal at RomAntica, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Coso Ristorante is another top choice with a popular menu. You could also check for a table at DEROMA - Farine Romane. As an establishment that gains consistently high praises from customers, it’s an ideal choice in Rome tonight.

Explore the vibrant nightlife at Sant' Eustachio Caffè after your meal, a hub for lively evenings and memorable moments. Or, head to Yellowsquare Rome for a great selection of flavorful drinks and a charming setting. Furthermore, Caffè Portofino is perfect for those looking to extend their night with a touch of local flavor.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in Italy.

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Day 10

Day 10

  • Rome
  • Naples
  • More

Drive 232 km, 3 hours 8 min

  • Pantheon
  • Trevi Fountain
  • Piazza di Spagna
  • More

On day 10 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Rome. In the evening, you’ll end up in Naples, where you will stay for 1 night.

Get ready to discover some of the most iconic wonders in Rome, including a monument and a public square. Start your day at Pantheon. This respected monument is a globally renowned place to see in Rome. Then, wander over to Trevi Fountain. If culturally significant sites excite you, this monument will be right up your alley. Nearby, you’ll also find Piazza Di Spagna. This romantic public square is a favorite among visitors.

At the end of the day, you will drive to Naples, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you explore more of Naples, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Savor the flavors at Opera Restaurant, a top pick for dinner tonight. Alternatively, Trattoria San Ferdinando beckons with its unique menu offerings. Also, consider Anonymous Trattoria Gourmet. With its consistent customer satisfaction, it’s an excellent option for dining in Naples tonight.

Explore the vibrant nightlife at Gran Caffè Cimmino after your meal, a hub for lively evenings and memorable moments. Or, head to Flanagan's Bar for a great selection of flavorful drinks and a charming setting. Furthermore, Bar Napoli is perfect for those looking to extend their night with a touch of local flavor.

Savor another day of unforgettable experiences in Italy!

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Day 11

Day 11

  • Naples - Departure day
  • More
  • Via Toledo
  • More

Day 11 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Naples before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

One of the best things to do on your last day is to explore Via Toledo, a street that captures the true essence of Naples. Take your time to uncover its best sides and enjoy its proximity to many of the area’s best attractions.

On your last day in Italy, take time to indulge in shopping at Naples’s popular marketplace, Via dei Mille. Look for keepsakes or souvenirs to remind you of your trip. Browse boutiques to find unique and stylish fashion pieces. If you’re in the mood for luxury shopping, high-end stores await you.

Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Naples.

Dine in style at Piazza Sannazaro, a top recommendation for dinner tonight. Or, for a change of pace, Osteria Il Gobbetto boasts a menu that's sure to impress.

You’ll then say farewell to Naples. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!

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