11-Day Italy Self-Drive Road Trip With Itinerary from Naples traveling north to Viterbo, Florence, Siena, and Rome

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Explore the best of Italy on a remarkable 11-day road trip! Combine exploration with relaxation on a self-drive tour featuring Naples, Tivoli, Viterbo, Florence, Pisa, Siena, and Rome.

This perfectly planned road trip itinerary takes you through some of the best places to see in Italy. You will spend 3 nights in Naples, 1 night in Viterbo, 3 nights in Florence, 1 night in Siena, and 2 nights in Rome. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Naples, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Trevi Fountain and Colosseum are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Pantheon, learn more about the unique Piazza Navona, and immerse yourself in the vibrant atmosphere of St. Peter's Basilica.

As you hit the open road and drive through Naples, Tivoli, Viterbo, Florence, Pisa, Siena, and Rome, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.

Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!

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Day 1

Day 1

  • Naples - Arrival day
  • More
  • Ovo Castle
  • More

Say hello to Naples! Your exciting road trip through Italy is just about to start. Navigating the top places to see in the region is a breeze with a car. The rental vehicle of your choice will be ready for pickup upon your arrival in the city. You will stay in Naples for 2 nights before you continue your adventure!

Naples is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Ovo Castle, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

As afternoon approaches, head to your chosen hotel in Naples. Check-in typically starts around 2 to 4 PM at hotels in Italy. We recommend staying at a central location for easy access to key areas in the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Naples, it's often a good idea to reserve a table in advance.

Enjoy a lovely meal at L'Oca Nera Irish Pub, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Mimì alla Ferrovia is another top choice with a popular menu. You could also check for a table at Spuzzulè Winebar. As an establishment that consistently gains high praises from customers, it’s an ideal choice in Naples tonight.

Continue your lively evening at Happening Cocktail Bar, a perfect place for winding down or revving up the night, depending on which mood you’re in. Shanti Art Musik Bar is another excellent bar that offers a great selection of drinks to suit any mood. If you prefer to go somewhere else, Gran Caffè Gambrinus ensures a night out tailored to your taste.

Raise a toast to the start of your 11-day road trip in Italy!

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Day 2

Day 2

  • Naples
  • More

Drive 12 km, 1 hour 7 min

  • Cappella Sansevero
  • Naples National Archaeological Museum
  • Castel Sant'Elmo
  • Chiaia
  • More

Day 2 of your road trip across Italy promises a magnificent time exploring what to see in Naples. You have 1 night left in Naples. Take the opportunity to experience more of the best attractions and activities in the city.

Don’t miss Chiaia today, a must-see neighborhood that offers a glimpse into the city’s vibrant character. Take your time to explore its best features, and enjoy the convenience of nearby top-rated landmarks.

Cappella Sansevero makes a great addition to your morning plans. This notable museum is an eye-catching place to see in Naples. Continue your discovery at Naples National Archaeological Museum, a heritage-rich museum with stories to tell.

As you stroll around Naples, take in the distinct atmosphere and learn what makes this city so unique. Maximize your sightseeing with a visit to Castel Sant'elmo. This captivating castle offers an instagrammable encounter with Naples. Whether you decide to get entrance tickets for all attractions or you prefer admiring from a distance, amazing experiences await on this day in Naples.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

Elevate your experience in Naples with a visit to the city's premier shopping location, Vomero. Explore unique boutique shops and uncover hidden gems along the way. For a cultural touch, look for artisan crafts that perfectly capture the charm of Italy. After shopping, enjoy nearby attractions, relax at a cafe, or simply people-watch and capture memorable photos.

After a day of adventure, treat yourself to an exquisite dinner at one of Naples's best restaurants.

Experience a harmony of flavors at Veritas in Naples by securing a reservation in advance. Known for its 1-star Michelin status, Veritas offers a delightful variety of dishes highlighting its delicious campanian and contemporary menu. If you're seeking an alternative culinary experience, be sure to explore Il Comandante, a highly recommended restaurant known for its enticing creative and mediterranean cuisine. This popular 1-star Michelin-awarded venue consistently exceeds expectations, ensuring a memorable holiday experience. Ready for another culinary adventure? Indulge your senses at ARIA, a highly acclaimed restaurant celebrated for its exceptional contemporary and modern menu.

Continue the enjoyment post-dinner at Archivio Storico - Cocktail Bar & Wonderfood, a cherished local gathering spot renowned for its welcoming atmosphere. Similarly, Archeobar offers a vibrant space for indulging in well-crafted drinks and engaging conversation. You may also want to check out Babette Pub. This bar is a favorite among both locals and visitors looking for a delightful evening out filled with laughter and fun.

As the sun sets, rest up and recharge for the next leg of your road trip in Italy.

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Day 3

Day 3

  • Naples
  • Viterbo
  • More

Drive 326 km, 3 hours 58 min

  • piazza del Plebiscito
  • Cattedrale di Santa Maria Assunta
  • Villa d'Este
  • Fontana dell'Ovato (o di Tivoli)
  • More

Dive into day 3 of your remarkable road trip in Italy. Today you'll explore 2 destinations, including Naples and Tivoli. At the end of the day, you’ll unwind at one of the finest accommodations in Viterbo, where you'll spend 1 night.

Visiting Piazza Del Plebiscito is always a good idea. This famous public square is a place that is appreciated by travelers and locals alike. Next, immerse yourself in the grand wonders of Cattedrale Di Santa Maria Assunta, a must-see church in the city.

Consider stopping for a small bite to eat or a drink at a local eatery to keep your energy going. When you’re ready, continue your discovery with a visit to Villa D'este. This locally renowned palace offers an enriching experience. For a change of pace, head to Fontana Dell'ovato (o Di Tivoli), where you can take in remarkable features. These sights offer a fulfilling end to a perfect day.

When you’re done exploring for the day, you’ll drive to your hotel in Viterbo. Check in and relax before you head out to tour the city.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Viterbo. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Relax and look forward to more memorable moments to come!

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Day 4

Day 4

  • Viterbo
  • Florence
  • More

Drive 228 km, 3 hours 20 min

  • Piazza del Plebiscito
  • Palazzo dei Papi di Viterbo
  • Terme dei papi
  • Therma Oasi
  • The Bagnaccio, spa park and botanical garden
  • More

On day 4 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, including Viterbo. When you’re not sightseeing, take time to relax at your chosen hotel in Florence, where you’ll be staying for 3 nights.

Start your day at Piazza Del Plebiscito. This romantic public square is a worthwhile place to see in Viterbo. Then, wander over to Palazzo Dei Papi Di Viterbo. If picture-perfect sites excite you, this palace will be right up your alley. Nearby, you’ll also find Terme Dei Papi. This romantic spa is a favorite among visitors.

Viterbo offers plenty to explore, ensuring every moment of your visit is filled with excitement and discovery. If you're up for more, Therma Oasi is an underrated spot in the city that will captivate you with its unique charm. When you’re done at the hot spring, don’t forget to check out the serene The Bagnaccio, Spa Park And Botanical Garden. Take a moment to appreciate the fascinating details of this curiosity-inducing spa.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Florence. Florence offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Florence. Enjoy a relaxing evening as you savor delicious local cuisine.

Experience a symphony of flavors at Enoteca Pinchiorri in Florence by securing a reservation in advance. Renowned for its 3-star Michelin distinction, Enoteca Pinchiorri delights its guests with its exceptional variety of meals showcasing delicious italian contemporary cuisine. For a palate-pleasing alternative, make sure to dine at Santa Elisabetta, acclaimed for its delectable creative and mediterranean specialties. This local 2-star Michelin establishment consistently satisfies guests, ensuring an unforgettable holiday experience. Want to go on another culinary journey? Delight your senses at Gucci Osteria da Massimo Bottura, a top-rated restaurant known for its outstanding menu. Known as a top-rated 1-star Michelin establishment, it's a top choice for italian contemporary and international cuisine in the city.

Unwind after your meal by stepping into Manifattura. This venue is celebrated for its extensive drink selections and cozy vibes. Alternatively, Se·sto On Arno Rooftop Bar offers a dynamic and energetic atmosphere for a glass or two. Don’t overlook Il Vinile, another top-rated bar in the area.

Relax and recharge in preparation for another adventurous day in Italy!

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Day 5

Day 5

  • Florence
  • More

Drive 1 km, 25 min

  • Ponte Vecchio
  • Uffizi Gallery
  • piazza della Signoria
  • Basilica of Santa Croce in Florence
  • Oltrarno
  • More

Day 5 of your road trip will take you to the best attractions Florence has to offer. Cherish the 2 nights you have left in the city and use the provided itinerary to discover what to see in Florence.

At the top of the list of things to do today is to explore Oltrarno, a neighborhood that captures the true essence of Florence. Take your time to uncover its best sides and enjoy its proximity to many of the area’s best attractions.

Start your day at Ponte Vecchio. This majestic historical landmark is an iconic place to see in Florence. Then, wander over to Uffizi Gallery. If picture-perfect sites excite you, this art gallery will be right up your alley. Nearby, you’ll also find Piazza Della Signoria. This enchanting public square is a favorite among visitors.

Florence offers plenty to explore, ensuring every moment of your visit is filled with excitement and discovery. If you're up for more, Basilica Of Santa Croce In Florence is a captivating spot in the city that will captivate you with its unique charm.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Florence. Enjoy a relaxing evening as you savor delicious local cuisine.

Savor the flavors at Ditta Artigianale, a top pick for dinner tonight. Alternatively, Trattoria Da Burde beckons with its unique menu offerings. Also, consider Casa Toscana. With its consistent customer satisfaction, it’s an excellent option for dining in Florence tonight.

After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at Bar 50 Rosso, a well-loved spot among locals and tourists. Or, head to Bitter Bar. This bar boasts a welcoming environment that is perfect for winding down. You could also continue your night at Archea Brewery, another top-rated place in the area.

Savor another day of unforgettable experiences in Italy!

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Day 6

Day 6

  • Florence
  • More

Drive 11 km, 57 min

  • Central Market
  • Cathedral of Santa Maria del Fiore
  • Galleria dell'Accademia
  • David
  • piazzale Michelangelo
  • More

Day 6 offers an itinerary packed with the best things to see in Florence. You’ll stay in Florence for 1 night more, offering you enough time to explore at a relaxed pace.

Check out the interesting food market, Central Market. Afterward, continue to Cathedral Of Santa Maria Del Fiore, a church every traveler should visit. As you explore Florence’s charming streets, take in the lively atmosphere and get to know the character of the city.

Next, make your way to Galleria Dell'accademia. This well-known art gallery is an essential stop. Following that, head to David, another must-visit site that will enhance your experience. Don’t forget to stop by Piazzale Michelangelo, an astonishing observation deck in the city.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Florence, it's often a good idea to reserve a table in advance.

Enjoy a delicious meal at Ristorante Buca Mario, a top-rated dining destination in Florence. If you're in the mood to try something new, consider Agricola Toscana, another top spot with a mouthwatering menu. You might also want to secure a reservation at Eataly Firenze. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Florence this evening.

After savoring a delicious meal, step into the vibrant nightlife at Gosh*, where the evening is just getting started. In the same way, Antico Caffè Del Moro - Art Bar Firenze offers a unique charm perfect for experiencing the local bar scene in Florence. Quelo Bar is another top-recommended bar that is sure to get you into the mood for some dancing and celebrating.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in Italy.

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Day 7

Day 7

  • Florence
  • Siena
  • More

Drive 213 km, 3 hours 13 min

  • Leaning Tower of Pisa
  • Angelo Caduto
  • Pisa Cathedral
  • Piazza del Duomo, Pisa
  • Campo santo
  • More

On day 7 of your road trip in Italy, your travel plans include 1 stop at the most scenic, wondrous, and interesting places in the region. Pisa are on today's agenda. In the evening, you’ll end up in Siena, where you will stay for 1 night.

Let Leaning Tower Of Pisa set the tone for the day. Spend some time admiring this picture-perfect monument before continuing your journey. Angelo Caduto is your next stop. This locally appreciated sightseeing destination is one of the best-rated sights in Florence.

Consider grabbing some lunch or a light snack to keep your energy going. Beyond the above-mentioned attractions, today is also the perfect time to visit Pisa Cathedral. This historic church is a sight to behold. To round off your sightseeing experience, visit Piazza Del Duomo, Pisa and Campo Santo.

At the end of the day, you will drive to Siena, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Siena, it's often a good idea to reserve a table in advance.

Treat yourself to a wonderful meal at Enoteca I Terzi, a top-rated dining spot in Siena. If you're in the mood for something new, try Ristorante Tar-Tufo, another premier location with a delectable menu. You might also want to book a table at Antica Trattoria Papei. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Siena.

Keep the excitement of the evening going by visiting a bar or two. Meet Life Cafè is an excellent place to start. You could also check out Maudit Pub, offering a different kind of charm. A last recommendation for the day is Bar Impero Siena. This bar promises an enjoyable experience with tasty drinks and a vibrant setting.

Head back to your accommodation in Siena and get some rest to prepare for another magical day of your road trip in Italy.

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Day 8

Day 8

  • Siena
  • Rome
  • More

Drive 241 km, 3 hours 23 min

  • Sistine Chapel
  • St Peter's Basilica
  • Saint Peter's Square
  • Vatican Museums
  • More

Experience an unparalleled adventure on day 8 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 place, which are Vatican City. At the end of the day, you will retreat to the hotel of your choice in Rome, where will spend 2 nights.

Sistine Chapel is an ideal stop early in the day. This famous chapel is a must-visit in the city.

One of the best things about exploring Siena on a self-guided tour is that you set the pace. There’s plenty of time for detours and discovering hidden gems. When you’re ready for your next stop, make your way to Saint Peter's Square, a locally renowned square in the city. If you’re up for more discoveries, don’t forget to reserve some time for Vatican Museums.

When you’re done exploring for the day, you’ll drive to your hotel in Rome. Check in and relax before you head out to tour the city.

Rome is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Rome.

Have a memorable dining experience in Rome by booking a table at La Pergola, a 3-star Michelin restaurant presenting an exceptional mediterranean and contemporary menu. For a different culinary experience in Rome, Il Pagliaccio shines as one of the top destinations, known for its delicious creative and innovative cuisine. This 2-star Michelin-awardee consistently earns high praises, making it a must-visit addition to your holiday experience. If you're looking for an alternative, Enoteca La Torre is known as a top local spot in Rome for its delicious mediterranean and creative cuisine. This 2-star Michelin awardee is a highly recommended choice for an unforgettable meal.

After savoring a delicious meal, step into the vibrant nightlife at La Botticella Of Poggi Giovanni, where the evening is just getting started. In the same way, Almalu Trastevere offers a unique charm perfect for experiencing the local bar scene in Rome. Bar Viminale Di Pepi Maurilio is another top-recommended bar that is sure to get you into the mood for some dancing and celebrating.

Raise your glass and celebrate another amazing day of your road trip in Italy!

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Day 9

Day 9

  • Rome
  • More

Drive 5 km, 48 min

  • Piazza Navona
  • Roman Forum
  • Colosseum
  • Trastevere
  • Monti
  • More

On day 9 of your road trip, you will have an entire day to discover what to see in Rome. You’ll stay in Rome for 1 night.

Set aside time today to explore Trastevere, a standout neighborhood that reflects the essence of the city. While you're there, you'll also be within reach of some of the city's top landmarks, making it easy to maximize your day. You might also want to visit Monti, a neighborhood offering another perspective on the city.

Piazza Navona is an ideal stop early in the day. This world-famous public square is a must-visit in the city. When you’re ready for your next discovery, continue to Roman Forum, which may be one of the most picture-perfect places you will experience today.

One of the best things about exploring Rome on a self-guided tour is that you set the pace. There’s plenty of time for detours and discovering hidden gems. When you’re ready for your next stop, make your way to Colosseum, a timeless archeological site in the city.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

Rome is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Rome.

Make sure to reserve a table at RomAntica, an iconic dining spot in Rome. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Coso Ristorante, a popular restaurant in Rome. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of DEROMA - Farine Romane, a hidden gem nestled in Rome. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

After your meal, keep the night alive at a bar like Sant' Eustachio Caffè, known for its lively atmosphere. Yellowsquare Rome is another top recommendation that provides the perfect setting with well-crafted drinks and a welcoming ambiance. Similarly, Caffè Portofino offers an excellent atmosphere for those looking to amp up the evening.

Relax and recharge in preparation for another adventurous day in Italy!

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Day 10

Day 10

  • Rome
  • Naples
  • More

Drive 232 km, 3 hours 8 min

  • Pantheon
  • Trevi Fountain
  • Piazza di Spagna
  • More

Your itinerary for day 10 of your road trip in Italy includes 1 stop and features some of the highlights of Rome. At the end of the day, enjoy the comforts of a top-rated hotel in Naples, where you'll spend 1 night.

Whatever your travel style is, Pantheon is an essential stop in Rome. This globally renowned monument provides an insightful glimpse into the city's identity. Next, discover Trevi Fountain, a grand monument, promising a delightful encounter.

Continue your sightseeing with a visit to Piazza Di Spagna, an iconic public square.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Naples. Naples offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a day of adventure, treat yourself to an exquisite dinner at one of Naples's best restaurants.

Treat yourself to a delicious dinner at Opera Restaurant, an excellent option for tonight's dining. Looking for something different? Trattoria San Ferdinando offers a tantalizing alternative with its diverse menu. And don’t miss Anonymous Trattoria Gourmet. Known for great service, it’s a fantastic choice for tonight in Naples.

If you’re not ready to end the night just yet, Gran Caffè Cimmino offers a perfect venue to relax and savor a drink. Similarly, Flanagan's Bar is well-suited for those looking to unwind in a social setting. Bar Napoli is another excellent spot to enjoy a nightcap after a delightful meal.

As the sun sets, rest up and recharge for the next leg of your road trip in Italy.

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Day 11

Day 11

  • Naples - Departure day
  • More
  • Via Toledo
  • More

Day 11 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Naples before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

One of the best things to do on your last day is to explore Via Toledo, a street that you shouldn't miss while in Naples. Take your time to uncover its best sides and enjoy its proximity to many of the area’s best attractions.

Make the most of your final day in Italy by visiting Naples’s iconic markets and shopping establishments in the buzzing Via dei Mille. Secure the perfect souvenirs for your family and friends back home or buy yourself a remembrance of your amazing vacation. You can also browse through boutiques for stylish fashion choices. Elevate your style with pieces from high-end retail stores.

Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Naples.

If you're in the mood to try something new, consider Osteria Il Gobbetto, another top spot with a mouthwatering menu.

You’ll then say farewell to Naples. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!

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Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

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