11-Day Sicily Self-Drive Road Trip With Itinerary from Palermo traveling east to Agrigento, Catania, Taormina, Syracuse, Ragusa, and Piazza Armerina

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Photo of Ibleo gardens in Ragusa, Sicily, Italy.
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Explore the best of Sicily on a remarkable 11-day road trip! Combine exploration with relaxation on a self-drive tour featuring Palermo, Agrigento, Catania, Motta Camastra, Francavilla di Sicilia, Taormina, Syracuse, Noto, Ragusa, Piazza Armerina, and Cefalù.

This perfectly planned road trip itinerary takes you through some of the best places to see in Sicily. You will spend 3 nights in Palermo, 1 night in Agrigento, 2 nights in Catania, 1 night in Taormina, 1 night in Syracuse, 1 night in Ragusa, and 1 night in Piazza Armerina. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Sicily. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Palermo, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Sicily on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Sicily. Valle Dei Templi and Palermo Cathedral are just a couple of the bucket-list attractions that await your discovery.

As you hit the open road and drive through Palermo, Agrigento, Catania, Motta Camastra, Francavilla di Sicilia, Taormina, Syracuse, Noto, Ragusa, Piazza Armerina, and Cefalù, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Sicily. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Sicily.

Throughout your road trip in Sicily, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Sicily.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Sicily fill up quickly, so book your spot early. Select a date and start planning your road trip in Sicily today!

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Driver’s age is 30 - 65
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Pick-up: 10:00
Drop-off: 10:00

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Day 1

Day 1

  • Palermo - Arrival day
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  • Foro Italico
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Your road trip adventure in Sicily begins as soon as you reach Palermo and pick up your car. You’ll stay here for 2 nights and explore what to see in Palermo, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.

Palermo is a beautiful city with plenty to discover. Taking a stroll in the city center is a great alternative. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Find your way to your hotel in Palermo. We recommend choosing a hotel in a central location for easy exploring. Check-in typically starts between 2 and 4 PM at hotels in Italy. Settle in and make plans for the evening.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Palermo, it's often a good idea to reserve a table in advance.

Raise a toast to the start of your 11-day road trip in Sicily!

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Day 2

Day 2

  • Palermo
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Drive 6 km, 49 min

  • Orto botanico di Palermo
  • Church of St. Mary of the Admiral
  • Fontana Pretoria
  • Quattro Canti
  • Palermo Cathedral
  • Norman Palace
  • More

Day 2 offers an itinerary packed with the best things to see in Palermo. You’ll stay in Palermo for 1 night more, offering you enough time to explore at a relaxed pace.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Sicily. You can explore and select activities under each day of your itinerary.

Palermo is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Palermo.

Get a good night's sleep and look forward to another great day on the road in Sicily!

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Day 3

Day 3

  • Palermo
  • Agrigento
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Drive 160 km, 2 hours 56 min

  • Museo archeologico regionale Pietro Griffo
  • Valle dei Templi
  • Temple of Heracles
  • Scala dei Turchi
  • More

Your itinerary for day 3 of your road trip in Sicily includes 2 stops and features some of the highlights of Agrigento and Scavuzzo. At the end of the day, enjoy the comforts of a top-rated hotel in Agrigento, where you'll spend 1 night.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Agrigento. Agrigento offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

Agrigento is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Agrigento.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in Sicily.

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Day 4

Day 4

  • Agrigento
  • Catania
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Drive 164 km, 2 hours 45 min

  • Castello Ursino
  • Greek - Roman theatre
  • Villa Bellini/Chiosco Bellini
  • Piazza Università
  • Fountain of the Elephant
  • Basilica Cattedrale di Sant'Agata
  • More

On day 4 of your road trip in Sicily, your travel plans include 1 stop at the most scenic, wondrous, and interesting places in the region. Catania are on today's agenda. In the evening, you’ll end up in Catania, where you will stay for 2 nights.

When you’re done exploring for the day, you’ll drive to your hotel in Catania. Check in and relax before you head out to tour the city.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Catania. Enjoy a relaxing evening as you savor delicious local cuisine.

Take some time to reflect on your day and savor another beautiful night in Sicily.

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Day 5

Day 5

  • Catania
  • More

Drive 123 km, 2 hours 22 min

  • Alcantara River Park
  • Gole Alcantara Botanical and Geological Park
  • Le Gurne dell'Alcantara
  • More

Greet day 5 of your road trip in Sicily with a smile and start your day with a hearty breakfast. You have 1 night to stay in Catania, so get ready to make the most of your time in the region. On the agenda for this day, you’ll find only the best things to see and do in Motta Camastra and Francavilla di Sicilia.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Catania.

Indulge in a memorable dining experience at one of Catania's most popular restaurants, and connect with friendly locals for a true cultural experience.

Raise your glass and celebrate another amazing day of your road trip in Sicily!

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Day 6

Day 6

  • Catania
  • Taormina
  • More

Drive 55 km, 1 hour 56 min

  • Isola Bella
  • Palazzo Corvaja
  • Ancient theatre of Taormina
  • Villa Comunale di Taormina
  • Porta Catania
  • Basilica of St. Nicholas of Bari
  • More

Dive into day 6 of your remarkable road trip in Sicily. Today you'll explore 2 destinations, including Mazzarò and Taormina. At the end of the day, you’ll unwind at one of the finest accommodations in Taormina, where you'll spend 1 night.

At the end of the day, you will drive to Taormina, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a day of adventure, treat yourself to an exquisite dinner at one of Taormina's best restaurants.

Raise your glass to another unforgettable day in Sicily!

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Day 7

Day 7

  • Taormina
  • Syracuse
  • More

Drive 122 km, 1 hour 49 min

  • Ear of Dionysius
  • Neapolis Archaeological Park
  • Cathedral of Syracuse
  • Island of Ortigia
  • Fountain of Diana
  • Temple of Apollo
  • More

On day 7 of your exciting self-drive vacation in Sicily, you’ll soak in the magnificence of 1 destination, including Syracuse. When you’re not sightseeing, take time to relax at your chosen hotel in Syracuse, where you’ll be staying for 1 night.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Syracuse. Syracuse offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Syracuse. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Relax and look forward to more memorable moments to come!

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Day 8

Day 8

  • Syracuse
  • Ragusa
  • More

Drive 105 km, 1 hour 52 min

  • Porta Reale o Ferdinandea
  • Roman Catholic Diocese of Noto
  • Nicolaci Palace
  • Giardino Ibleo
  • More

Experience an unparalleled adventure on day 8 of your road trip in Sicily. This exciting part of your journey invites you to discover the renowned landmarks in 2 places, which are Noto and Ragusa. At the end of the day, you will retreat to the hotel of your choice in Ragusa, where will spend 1 night.

When you’re done exploring for the day, you’ll drive to your hotel in Ragusa. Check in and relax before you head out to tour the city.

Indulge in a memorable dining experience at one of Ragusa's most popular restaurants, and connect with friendly locals for a true cultural experience.

Raise your glass and celebrate another amazing day of your road trip in Sicily!

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Day 9

Day 9

  • Ragusa
  • Piazza Armerina
  • More

Drive 120 km, 2 hours 17 min

  • Duomo di San Giorgio
  • Villa Romana del Casale
  • Palazzo Trigona della Floresta e di San Cono (Museo Della Città e del Territorio di Piazza Armerina)
  • More

Your itinerary for day 9 of your road trip in Sicily includes 2 stops and features some of the highlights of Ragusa and Piazza Armerina. At the end of the day, enjoy the comforts of a top-rated hotel in Piazza Armerina, where you'll spend 1 night.

At the end of the day, you will drive to Piazza Armerina, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Piazza Armerina, it's often a good idea to reserve a table in advance.

Savor another day of unforgettable experiences in Sicily!

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Day 10

Day 10

  • Piazza Armerina
  • Palermo
  • More

Drive 202 km, 3 hours 9 min

  • Rocca di Cefalù
  • Cathedral of Cefalù
  • Bastione di Capo Marchiafava
  • Porta della Pescara (Porta Marina)
  • Lavatoio Medievale Fiume Cefalino - Cefalù (pa)
  • Cefalù Beach
  • More

On day 10 of your road trip in Sicily, your travel plans include 1 stop at the most scenic, wondrous, and interesting places in the region. Cefalù are on today's agenda. In the evening, you’ll end up in Palermo, where you will stay for 1 night.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Palermo. Palermo offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

Palermo is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Palermo.

Say good night to Palermo and look forward to another great day of your road trip in Sicily!

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Day 11

Day 11

  • Palermo - Departure day
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  • Catacombe dei Cappuccini
  • More

Day 11 of your road trip in Sicily is your departure day. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

Secure the perfect souvenirs for your family and friends back home or buy yourself a remembrance of your amazing vacation.

Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Sicily!

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Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

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Your trip is protected, personalized, and priced right. No surprises, no stress.

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