11-Day Italy Self-Drive Road Trip With Itinerary from Perugia traveling south to L'aquila, Naples, Rome, and Siena
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Explore the best of Italy on a 11-day road trip! Uncover hidden gems and experience the rich culture firsthand as you journey through Perugia, L'aquila, Caserta, Pompei, Naples, Amalfi, Rome, Siena, and Santa Maria degli Angeli. This road trip itinerary in Italy seamlessly combines exploration with relaxation.
This perfectly planned road trip itinerary in Italy takes you through some of the best places to see in the country. You will spend 2 nights in Perugia, 1 night in L'aquila, 2 nights in Naples, 3 nights in Rome, and 2 nights in Siena. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!
With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.
Upon arriving in Perugia, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.
An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Trevi Fountain and Colosseum are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Pantheon, learn more about the unique Piazza Navona, and immerse yourself in the vibrant atmosphere of St. Peter's Basilica.
As you hit the open road and drive through Perugia, L'aquila, Caserta, Pompei, Naples, Amalfi, Rome, Siena, and Santa Maria degli Angeli, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.
Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.
This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.
The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!
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Day 1
- Perugia - Arrival day
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- Piazza IV Novembre
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Your road trip adventure in Italy begins as soon as you reach Perugia and pick up your car. You’ll stay in Perugia for 1 night and explore the best things to see and do, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.
Perugia is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Piazza Iv Novembre, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.
As afternoon approaches, head to your chosen hotel in Perugia. Check-in typically starts around 2 to 4 PM at hotels in Italy. We recommend staying at a hotel in a central location for easy access to the best attractions, restaurants, and bars in the city.
As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Perugia, it's often a good idea to reserve a table in advance.
Dine in style at Ristorante Settimo Sigillo, a top recommendation for dinner tonight. Or, for a change of pace, Caffè Baglioni boasts a menu that's sure to impress. Also, be sure to check out Bar Pellas. Known as a local hotspot, it’s a great choice for tonight in Perugia.
After your meal, keep the night alive at a bar like Tommi Bar, known for its lively atmosphere. Valentina is another top recommendation that provides the perfect setting with well-crafted drinks and a welcoming ambiance. Similarly, Caffe Dal Perugino offers an excellent atmosphere for those looking to amp up the evening.
Raise a toast to the start of your 11-day road trip in Italy!
Day 2
- Perugia
- L'Aquila
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Drive 172 km, 2 hours 47 min
- Carducci Gardens
- Porta Marzia
- Rocca Paolina
- National Archaeological Museum of Umbria
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Embark on another extraordinary experience on day 2 of your road trip in Italy. Today, you will make 1 stop and experience some of the highlights of Perugia. At the end of the day, you will enjoy the comforts of a top-rated hotel in L'aquila, which will be your home away from home for 1 night.
Today’s itinerary in Perugia covers several incredible sights, including a park, a monument, a historical landmark, a museum and much more! Start your adventure at Carducci Gardens. This intriguing park is a place that is appreciated by travelers and locals alike. Next, immerse yourself in the picture-perfect wonders of Porta Marzia, a must-see monument in the city.
Consider stopping for a small bite to eat or a drink at a local eatery to keep your energy going. When you’re ready, continue your discovery with a visit to Rocca Paolina. This intriguing historical landmark offers an enriching experience. For a change of pace, head to National Archaeological Museum Of Umbria, where you can take in photogenic features. These sights offer a fulfilling end to a perfect day.
After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in L'aquila. L'aquila offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.
As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in L'aquila. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.
Experience a symphony of flavors at FØRMA contemporary restaurant in L'aquila by securing a reservation in advance. Renowned for its Bib Gourmand distinction, FØRMA contemporary restaurant delights its guests with its exceptional variety of meals showcasing delicious contemporary and creative cuisine. Or, if you're feeling adventurous, why not try DECA? It's another excellent option with a diverse menu.
If you’re not ready to end the night just yet, Art Cafè L'aquila offers a perfect venue to relax and savor a drink.
Raise your glass and celebrate another amazing day of your road trip in Italy!
Day 3
- L'Aquila
- Naples
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Drive 282 km, 4 hours 5 min
- Palace of Caserta
- Giardini Reali - Parco Reggia di Caserta
- Archaeological Park of Pompeii
- Teatro Grande
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Experience an unparalleled adventure on day 3 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 2 vibrant destinations - Caserta and Pompei. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Naples. You will spend 2 nights here for some well-deserved relaxation.
Set out on a day brimming with family-friendly attractions, romantic experiences, and breathtaking views. Start at the interesting Palace Of Caserta, an UNESCO world heritage-designated palace in L'aquila. Next, go to Giardini Reali - Parco Reggia Di Caserta.
After visiting Palace Of Caserta and Giardini Reali - Parco Reggia Di Caserta, have a stroll along L'aquila's streets and take in the local charm. Continue your sightseeing by heading to Archaeological Park Of Pompeii. This awe-inspiring archeological site offers a unique experience. Teatro Grande is another noteworthy attraction worthwhile a visit.
When you’re done exploring for the day, you’ll drive to your hotel in Naples. Check in and spend some time relaxing before you head out to tour the city.
As dinnertime approaches, it's time to head out for a bite to eat in Naples. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.
Enjoy an outstanding dining experience at Veritas, a 1-star Michelin restaurant offering an exceptional campanian and contemporary menu. Alternatively, if you're in the mood for something different, consider the nearby 1-star Michelin-awardee, Il Comandante, known for its delicious creative and mediterranean cuisine. Another highly-recommended place to eat in Naples is ARIA, a renowned restaurant with a 1-star Guide Michelin recognition and a delicious contemporary and modern menu.
Explore the vibrant nightlife at Happening Cocktail Bar after your meal, a hub for lively evenings and memorable moments. Or, head to Shanti Art Musik Bar for a great selection of flavorful drinks and a charming setting. Furthermore, Gran Caffè Gambrinus is perfect for those looking to extend their night with a touch of local flavor.
Relax and reminisce about your day in Italy and look forward to more memorable moments to come!
Day 4
- Naples
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Drive 126 km, 3 hours 36 min
- Amalfi Coast
- Castel Nuovo
- piazza del Plebiscito
- Ovo Castle
- Via Toledo
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On day 4 of your road trip in Italy, you’ll start and end your day in Naples, but spend the day exploring what’s beyond the city. Since you will return to Naples for 1 night more, there’s no need to rush. Experience Amalfi and Naples to the fullest today with this curated day itinerary!
A visit to Via Toledo in Amalfi is a must on the agenda today. This street is full of hidden gems and character, perfect for a leisurely stroll. Plus, you’ll be close to some of the city’s most famous sights.
Immerse yourself in Naples’s rich culture with today's sightseeing itinerary. Start your journey at Amalfi Coast. Next, dive into the culturally significant features of Castel Nuovo, a must-visit castle in the village.
In between sights, stop by local stores, picturesque photo spots, and small eateries. When you’re ready for your next attraction, proceed to Piazza Del Plebiscito, a famous public square. For a change of scene, check out Ovo Castle, known for its romantic features.
When you’re done exploring for the day, you’ll return to Naples and your accommodation.
As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Naples. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.
Make sure to reserve a table at Antica Pizzeria Di Matteo, an iconic dining spot in Naples. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Mercure Napoli Centro Angioino, a popular restaurant in Naples. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of La Lazzara Trattoria e Pizzeria, a hidden gem nestled in Naples. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.
Explore the vibrant nightlife at Archivio Storico - Cocktail Bar & Wonderfood after your meal, a hub for lively evenings and memorable moments. Or, head to Archeobar for a great selection of flavorful drinks and a charming setting. Furthermore, Babette Pub is perfect for those looking to extend their night with a touch of local flavor.
As the sun sets on another day of adventure, rest up and recharge for the next leg of your road trip in Italy.
Day 5
- Naples
- Rome
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Drive 241 km, 3 hours 29 min
- St Peter's Basilica
- Sistine Chapel
- Saint Peter's Square
- Vatican Museums
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Dive into day 5 of your remarkable road trip in Italy. Today you will explore Vatican City, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Rome. You’ll stay here for 3 nights.
Sistine Chapel is your next stop. This top-rated chapel is one of the best-rated sights in Naples.
Consider grabbing some lunch or a light snack to keep your energy going. Beyond the above-mentioned attractions, today is also the perfect time to visit Saint Peter's Square. To round off your sightseeing experience, visit Vatican Museums.
At the end of the day, you will drive to Rome, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.
Indulge in a memorable dining experience at one of Rome's most popular restaurants, and connect with friendly locals for an authentic adventure.
Start your culinary exploration in Rome by securing a reservation at La Pergola. This renowned restaurant holds 3 Michelin star and offers an exceptional menu of mediterranean and contemporary cuisine. For another dining delight, visit Il Pagliaccio, celebrated for its delectable creative and innovative menu. This acclaimed 2-star Michelin-recipient consistently leaves guests satisfied, making it a must-visit during your holiday. Looking for a different experience? Discover Enoteca La Torre, a top local spot known for its tantalizing mediterranean and creative menu. With a 2-star Michelin recognition, it guarantees an exceptional dining adventure.
To truly maximize your evening out, consider visiting La Botticella Of Poggi Giovanni after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to Almalu Trastevere, another bar with an inviting ambiance. Similarly, Bar Viminale Di Pepi Maurilio also offers a great atmosphere, ensuring a night filled with enjoyment and relaxation.
Celebrate another amazing day of your road trip adventure in Italy!
Day 6
- Rome
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Drive 11 km, 1 hour 19 min
- Castel Sant'Angelo
- Piazza Navona
- Pantheon
- Trevi Fountain
- Villa Borghese
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Day 6 of your road trip will take you to the best attractions Rome has to offer. Cherish the 2 nights you have left in Rome by discovering the best things there are to see and do in the city.
Bring your curiosity for today’s adventure around Rome. Some of the city’s most loved attractions await! Castel Sant'angelo is the perfect place to start. This castle is one of the most impressive places to visit in Rome. Next, head to Piazza Navona, a timeless public square, known for its visually striking features.
In between the sights, don’t hesitate to take small detours to explore local stores and eateries. When you’re ready to continue your adventure, head to Pantheon. This photogenic monument is a highly recommended experience. Nearby, you'll also find Trevi Fountain and Villa Borghese. Visit these for an interesting touch to your journey.
Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.
As dinnertime approaches, it's time to head out for a bite to eat in Rome. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.
Enjoy a lovely meal at RomAntica, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Coso Ristorante is another top choice with a popular menu. You could also check for a table at DEROMA - Farine Romane. As an establishment that gains consistently high praises from customers, it’s an ideal choice in Rome tonight.
Continue the enjoyment post-dinner at Sant' Eustachio Caffè, a cherished local gathering spot renowned for its welcoming atmosphere. Similarly, Yellowsquare Rome offers a vibrant space for indulging in well-crafted drinks and engaging conversation. You may also want to check out Caffè Portofino. This bar is a favorite among both locals and visitors looking for a delightful evening out filled with laughter and fun.
As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in Italy.
Day 7
- Rome
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Drive 3 km, 41 min
- Altare della Patria
- Roman Forum
- Colosseum
- Trastevere
- Monti
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Day 7 of your road trip across Italy promises a magnificent time exploring Rome. You have 1 night left in Rome. Take the opportunity to experience more of the best attractions and activities in the city.
A top thing to do today is to explore Trastevere, a must-see neighborhood in Rome. It's the perfect starting point for touring the top attractions in the area. You can also visit Monti, an ideal neighborhood for continued sightseeing.
Whether you prefer a leisurely exploration or a more fast-paced adventure, this itinerary in Rome allows for both. Start by heading to Altare Della Patria. This well-known monument provides an insightful glimpse into the city's identity. Next, discover Roman Forum, an UNESCO world heritage-listed archeological site, promising a delightful encounter.
Continue your sightseeing with a visit to Colosseum, an iconic archeological site.
Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.
As you explore more of Rome, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.
Enjoy a delicious meal at Hotel de Russie, a highly-rated dining destination in Rome. If you're eager to try something different, consider La Taverna Italiana, another top spot with a tantalizing menu. You might also want to secure a reservation at The Parrot Bar. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Rome this evening.
After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at The Apartment Bar Roma, a well-loved spot among locals and tourists. Or, head to Hotel Hassler Roma. This bar boasts a welcoming environment that is perfect for winding down.
Say good night to Rome and look forward to another great day of your road trip in Italy!
Day 8
- Rome
- Siena
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Drive 239 km, 3 hours 11 min
- Piazza di Spagna
- Spanish Steps
- piazza del Popolo
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On day 8 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Rome. In the evening, you’ll end up in Siena, where you will stay for 2 nights.
Start by visiting Piazza Di Spagna, a prime spot to begin your journey. This culturally significant public square is sure to impress. Next on your list is Spanish Steps, another must-visit landmark and extraordinary public square renowned for its visually striking features.
While exploring and sightseeing, take time to savor the culture of Rome by sampling some local delicacies. When you’re ready for more sightseeing, head to Piazza Del Popolo. This visually striking public square is an essential place to visit for anyone looking for the full Rome experience.
After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Siena. Siena offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.
As you explore more of Siena, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.
Savor the flavors at Enoteca I Terzi, a top pick for dinner tonight. Alternatively, Ristorante Tar-Tufo beckons with its unique menu offerings. Also, consider Antica Trattoria Papei. With its consistent customer satisfaction, it’s an excellent option for dining in Siena tonight.
Unwind after your meal by stepping into Meet Life Cafè. This venue is celebrated for its extensive drink selections and cozy vibes. Alternatively, Maudit Pub offers a dynamic and energetic atmosphere for a glass or two. Don’t overlook Bar Impero Siena, another top-rated bar in the area.
Take some time to reflect on your day and savor another beautiful night in Italy.
Day 9
- Siena
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Drive 3 km, 44 min
- Fortezza Medicea
- Loggia del Papa, Siena
- piazza del Campo
- Opera delle Metropolitana
- Siena Cathedral
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Day 9 offers a multitude of experiences. You will stay in Siena for 1 night more, offering you enough time to explore at a relaxed pace.
Today’s well-planned self-sightseeing route offers several fun adventures, breathtaking views, and picturesque spots. Whether you decide to explore Siena on foot, use public transport, or join a guided tour, there are a few attractions you don’t want to miss. Fortezza Medicea (siena) is the first of them. Spend some time admiring this culturally significant monument before continuing your journey. Loggia Del Papa, Siena is your next stop. This worthwhile monument is one of the best-rated sights in Siena.
Consider grabbing some lunch or a light snack to keep your energy going. Beyond the above-mentioned attractions, today is also the perfect time to visit Piazza Del Campo. This enchanting public square is a sight to behold. To round off your sightseeing experience, visit Opera Delle Metropolitana and Siena Cathedral.
Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.
As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Siena. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.
Enjoy a lovely dining experience at Osteria Quattro Venti, a popular restaurant in Siena. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Siena at Fischi per Fiaschi, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated Osteria da Divo. It’s yet another ideal choice to enhance your time in Siena tonight.
Continue your lively evening at Charlie Mixology Bar Di Aldinucci Riccardo, a perfect place for winding down or revving up the night, depending on which mood you’re in. Bar Pinacoteca is another excellent bar that offers a great selection of drinks to suit any mood. If you prefer to go somewhere else, San Paolo Pub ensures a night out tailored to your taste.
Get a good night's sleep and look forward to another great day on the road in Italy!
Day 10
- Siena
- Perugia
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Drive 156 km, 2 hours 38 min
- Basilica of San Francesco d'Assisi
- Cathedral of San Rufino
- Basilica di Santa Chiara
- Basilica of Santa Maria degli Angeli
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On day 10 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, Santa Maria degli Angeli. When you’re not sightseeing, take time to relax at your selected hotel in Perugia, where you’ll be staying for 1 night.
Basilica Of San Francesco D'assisi is must-visit church and a great starting point for the day. Next, continue your journey to Cathedral Of San Rufino, a frequently visited church, located just a leisurely stroll away. Next, head to Basilica Di Santa Chiara, an awe-inspiring church, also available for your discovery today.
When you’re done exploring for the day, you’ll drive to your hotel in Perugia. Check in and spend some time relaxing before you head out to tour the city.
After a day of adventure, treat yourself to an exquisite dinner at one of Perugia's best restaurants.
Dine in style at La Taverna, a top recommendation for dinner tonight. Or, for a change of pace, Ristorante del Sole boasts a menu that's sure to impress. Also, be sure to check out Al Mangiar Bene. Known as a local hotspot, it’s a great choice for tonight in Perugia.
Keep the excitement of the evening going by visiting a bar or two. Caffè Fortebraccio is an excellent place to start. You could also check out Caffe Del Banco, offering a different kind of charm. A last recommendation for the day is Dempsey's Perugia. This bar promises an enjoyable experience with tasty drinks and a vibrant setting.
Raise your glass to another unforgettable day in Italy!
Day 11
- Perugia - Departure day
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- Etruscan Arch
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Day 11 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Perugia before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.
If you're up for some more sightseeing, we recommend visiting Etruscan Arch, an instagrammable historical landmark before you head out.
On your last day in Italy, take time to indulge in shopping at Perugia’s popular marketplace. Look for keepsakes or souvenirs to remind you of your trip.
Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Perugia.
You’ll then say farewell to Perugia. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!
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