11-Day Italy Self-Drive Road Trip With Itinerary from Pescara traveling west to Rome, Florence, Siena, and Perugia
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Description
Escape the ordinary with this exciting 11-day road trip through Italy. Explore the diverse landscapes, lively cities, and beyond. Pack your bags, hit the road, and prepare for an unforgettable journey!
This perfectly planned road trip itinerary in Italy takes you through some of the best places to see in the country. You will spend 2 nights in Pescara, 2 nights in Rome, 2 nights in Florence, 2 nights in Siena, and 2 nights in Perugia. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!
With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.
Upon arriving in Pescara, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.
An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Trevi Fountain and Colosseum are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Pantheon, learn more about the unique Piazza Navona, and immerse yourself in the vibrant atmosphere of St. Peter's Basilica.
As you hit the open road and drive through Pescara, Rome, Florence, Pisa, Lucca, Siena, Santa Maria degli Angeli, Perugia, Fano Adriano, and Pietracamela, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.
Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.
This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.
The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!
Itinerary summary
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Day 1
- Pescara - Arrival day
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- Locomotiva FS 740351
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Your road trip adventure in Italy begins as soon as you reach Pescara and pick up your car. You’ll stay in Pescara for 1 night and explore the best things to see and do, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.
Pescara is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Locomotiva Fs 740.351, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.
Make your way to your chosen hotel. Check-in typically starts between 2 and 4 PM in Pescara. Make yourself at home and enjoy some downtime before heading out again.
As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Pescara, it's often a good idea to reserve a table in advance.
Have a fantastic dining experience at Taverna 58, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Ristorante Carlo Ferraioli offers an enticing alternative with its varied menu. Additionally, Sesamo Nero is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Pescara.
Continue your lively evening at Posa Caffè Pescara, a perfect place for winding down or revving up the night, depending on which mood you’re in. Bar Mixer is another excellent bar that offers a great selection of drinks to suit any mood. If you prefer to go somewhere else, Temple Bar Irish Pub ensures a night out tailored to your taste.
Raise a toast to the start of your 11-day road trip in Italy!
Day 2
- Pescara
- Rome
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Drive 213 km, 3 hours 15 min
- Colosseum
- Roman Forum
- Altare della Patria
- Pantheon
- Piazza Navona
- More
On day 2 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, Rome. When you’re not sightseeing, take time to relax at your selected hotel in Rome, where you’ll be staying for 2 nights.
Brace yourself for today’s incredible lineup of attractions in Pescara, featuring fun adventures, scenic views, and photo-friendly spots. Start at Colosseum, a globally renowned archeological site in the city. Then, head to Roman Forum and soak in the ambiance of this picture-perfect archeological site.
There are many interesting places to see in Pescara, and when you are ready for more, go to Altare Della Patria. This is one of the city’s most captivating masterful spots of interest. After exploring the monument, visit the timeless Pantheon. Not far away, you'll also find Piazza Navona. This public square is a history-steeped highlight in Pescara.
After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Rome. Rome offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.
As you explore more of Rome, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.
Dine in style at La Bottega Roma, a top recommendation for dinner tonight. Or, for a change of pace, Pasta In Corso boasts a menu that's sure to impress. Also, be sure to check out Trattoria Vecchia Roma. Known as a local hotspot, it’s a great choice for tonight in Rome.
Explore the vibrant nightlife at La Botticella Of Poggi Giovanni after your meal, a hub for lively evenings and memorable moments. Or, head to Almalu Trastevere for a great selection of flavorful drinks and a charming setting. Furthermore, Bar Viminale Di Pepi Maurilio is perfect for those looking to extend their night with a touch of local flavor.
Head back to your accommodation in Rome and get some rest in preparation for another magical day of your road trip in Italy!
Day 3
- Rome
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Drive 9 km, 57 min
- St Peter's Basilica
- piazza del Popolo
- Piazza di Spagna
- Trevi Fountain
- Trastevere
- Via del Corso
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On day 3 of your road trip in Italy, you’ll start and end your day in Rome, but spend the day exploring what’s beyond the city. Since you will return to Rome for 1 night more, there’s no need to rush. Experience Vatican City and Rome to the fullest today with this curated day itinerary!
Make sure to visit Trastevere, a popular neighborhood in Vatican City. Spend some time wandering around the area and soak in its distinctive charm. You’ll also discover that several of the city’s must-see attractions are just around the corner. You can also explore Via del Corso today, a street that’s well worth a visit.
Rome is home to plenty of attractions that offer family-friendly attractions, romantic experiences, and breathtaking views! Start at St. Peter's Basilica, an iconic major basilica that is worthwhile a visit in the city. Nearby, you’ll find Piazza Del Popolo, enchanting visitors with its history-steeped appeal. Continue your exploration at Piazza Di Spagna. This public square is one of the city’s most world-famous spots.
Enjoy the freedom of exploring Rome at your own pace and find hidden gems along the way. If you want to see more picture-perfect spots, make sure to visit Trevi Fountain.
When you’re done exploring for the day, you’ll return to Rome and your accommodation.
After a day of adventure, treat yourself to an exquisite dinner at one of Rome's best restaurants.
Have a fantastic dining experience at RomAntica, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Coso Ristorante offers an enticing alternative with its varied menu. Additionally, DEROMA - Farine Romane is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Rome.
After enjoying a fulfilling meal, continue your evening at Sant' Eustachio Caffè, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, Yellowsquare Rome offers a welcoming atmosphere for easing into the nightlife. Similarly, Caffè Portofino provides an excellent environment for a relaxed and enjoyable evening.
Raise your glass and celebrate another amazing day of your road trip in Italy!
Day 4
- Rome
- Florence
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Drive 282 km, 3 hours 36 min
- The Boboli Gardens
- Ponte Vecchio
- Uffizi Gallery
- Loggia dei Lanzi
- piazza della Signoria
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On day 4 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Florence. In the evening, you’ll end up in Florence, where you will stay for 2 nights.
Get ready for an exciting day in Rome. Today’s sightseeing agenda includes a botanical garden, a historical landmark, an art gallery, a public square and much more! Begin your adventure at The Boboli Gardens. This is a well-known botanical garden you should not miss. Another must-see is Ponte Vecchio, a world-famous historical landmark in Rome.
When you’re ready for the next sight, head to Uffizi Gallery. From there, take a leisurely stroll to Loggia Dei Lanzi, another of the city’s increasingly popular attractions. We recommend continuing your self-guided tour at Piazza Della Signoria, a romantic place of interest in the city.
When you’re done exploring for the day, you’ll drive to your hotel in Florence. Check in and spend some time relaxing before you head out to tour the city.
After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Florence. Enjoy a satisfying meal that will recharge you for tonight's adventures.
Make sure to reserve a table at Ristorante Oliviero 1962, an iconic dining spot in Florence. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Di Poneta Novoli, a popular restaurant in Florence. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Caffe San Firenze, a hidden gem nestled in Florence. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.
Extend your evening after a delightful meal by visiting Manifattura, which offers the perfect atmosphere for a night out. Moreover, Se·sto On Arno Rooftop Bar is another popular option for a drink or two. Likewise, Il Vinile also provides a great ambiance for reminiscing about the day and raising a toast to your vacation.
Relax and reminisce about your day in Italy and look forward to more memorable moments to come!
Day 5
- Florence
- More
Drive 6 km, 1 hour 32 min
- piazzale Michelangelo
- Basilica of Santa Croce in Florence
- Cathedral of Santa Maria del Fiore
- Central Market
- Galleria dell'Accademia
- David
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Day 5 of your road trip across Italy promises a magnificent time exploring Florence. You have 1 night left in Florence. Take the opportunity to experience more of the best attractions and activities in the city.
Begin your adventure at Piazzale Michelangelo. This is a famous observation deck you should not miss. Another must-see is Basilica Of Santa Croce In Florence, a locally renowned church in Florence.
When you’re ready for the next sight, head to Cathedral Of Santa Maria Del Fiore. From there, take a leisurely stroll to Central Market, another of the city’s notable attractions. We recommend continuing your self-guided tour at Galleria Dell'accademia, an eye-catching place of interest in the city. If time allows, add David to your itinerary. This locally renowned statue offers the perfect finishing touch to your day in Florence.
Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.
As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Florence. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.
Enjoy a delicious meal at Ditta Artigianale, a highly-rated dining destination in Florence. If you're eager to try something different, consider Trattoria Da Burde, another top spot with a tantalizing menu. You might also want to secure a reservation at Casa Toscana. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Florence this evening.
Let the evening flow smoothly from dinner to drinks at Bar 50 Rosso, a top-rated bar in the area. For other recommendations, Bitter Bar provides a perfect setting for rounding out your night with style and great drinks. Likewise, Archea Brewery offers a memorable night with diverse drink options and excellent service.
Relax and reminisce about your day in Italy and look forward to more memorable moments to come!
Day 6
- Florence
- Siena
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Drive 245 km, 3 hours 33 min
- Pisa Cathedral
- Piazza del Duomo, Pisa
- Leaning Tower of Pisa
- Walls of Lucca
- Porta San Pietro
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Experience an unparalleled adventure on day 6 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 2 vibrant destinations - Pisa and Lucca. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Siena. You will spend 2 nights here for some well-deserved relaxation.
Bring your curiosity for today’s adventure around Florence. Some of the city’s most loved attractions await! Pisa Cathedral is the perfect place to start. This church is one of the most increasingly popular places to visit in Florence. Next, head to Piazza Del Duomo, Pisa, an iconic public square, known for its culturally significant features.
In between the sights, don’t hesitate to take small detours to explore local stores and eateries. When you’re ready to continue your adventure, head to Leaning Tower Of Pisa. This culturally significant monument is a highly recommended experience. Nearby, you'll also find Mura Di Lucca and Porta San Pietro. Visit these for an interesting touch to your journey.
At the end of the day, you will drive to Siena, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.
Indulge in a memorable dining experience at one of Siena's most popular restaurants, and connect with friendly locals for an authentic adventure.
Enjoy a lovely meal at Enoteca I Terzi, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Ristorante Tar-Tufo is another top choice with a popular menu. You could also check for a table at Antica Trattoria Papei. As an establishment that gains consistently high praises from customers, it’s an ideal choice in Siena tonight.
Round off your dining experience by visiting Meet Life Cafè, a prime location for a drink. Alternatively, explore the distinctive characteristics of Maudit Pub, a bar catering to every mood and preference. Bar Impero Siena likewise offers a unique atmosphere, perfect for a memorable night out.
Relax and recharge in preparation for another adventurous day in Italy!
Day 7
- Siena
- More
Drive 3 km, 59 min
- Porta Camollia, Siena
- Fortezza Medicea
- Fontebranda
- Battistero di San Giovanni Battista
- Siena Cathedral
- piazza del Campo
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Day 7 offers a multitude of experiences. You will stay in Siena for 1 night more, offering you enough time to explore at a relaxed pace.
Get ready for a day filled with family-friendly attractions, scenic views, and photo-friendly spots in the charming city of Siena. Your adventure starts at Porta Camollia, Siena, a locally appreciated local hot spot. Another notable attraction to explore is Fortezza Medicea (siena). This frequently visited monument is known for its breathtaking appeal.
After soaking in the highlights of these sights, take some time to wander Siena's streets and immerse yourself in the local atmosphere. When you're ready to continue your sightseeing adventure, head to Fontebranda. This standout historical landmark offers a fascinating experience that many visitors find memorable. Battistero Di San Giovanni Battista is also worth visiting, along with Siena Cathedral. These standout landmarks offer unique experiences that add to the day’s enjoyment. End your day at Piazza Del Campo. This impressive public square provides a fitting finale to your sightseeing.
Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.
As dinnertime approaches, it's time to head out for a bite to eat in Siena. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.
Make sure to reserve a table at Osteria Quattro Venti, an iconic dining spot in Siena. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Fischi per Fiaschi, a popular restaurant in Siena. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Osteria da Divo, a hidden gem nestled in Siena. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.
After savoring a delicious meal, step into the vibrant nightlife at Charlie Mixology Bar Di Aldinucci Riccardo, where the evening is just getting started. In the same way, Bar Pinacoteca offers a unique charm perfect for experiencing the local bar scene in Siena. San Paolo Pub is another top-recommended bar that is sure to get you into the mood for some dancing and celebrating.
As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in Italy.
Day 8
- Siena
- Perugia
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Drive 158 km, 2 hours 50 min
- Basilica of San Francesco d'Assisi
- Piazza del Comune
- Mount Subasio
- San Damiano
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Embark on another extraordinary experience on day 8 of your road trip in Italy. Today, you will make 1 stop and experience some of the highlights of Santa Maria degli Angeli. At the end of the day, you will enjoy the comforts of a top-rated hotel in Perugia, which will be your home away from home for 2 nights.
Today’s agenda in Siena includes a church, a public square, and a mountain range. Basilica Of San Francesco D'assisi is must-visit church and a great starting point for the day. Next, continue your journey to Piazza Del Comune, an increasingly popular public square, located just a leisurely stroll away. Next, head to Mount Subasio, an eye-catching mountain range, also available for your discovery today.
After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Perugia. Perugia offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.
After a day of adventure, treat yourself to an exquisite dinner at one of Perugia's best restaurants.
Make sure to reserve a table at Ristorante Settimo Sigillo, an iconic dining spot in Perugia. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Caffè Baglioni, a popular restaurant in Perugia. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Bar Pellas, a hidden gem nestled in Perugia. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.
Let the evening flow smoothly from dinner to drinks at Tommi Bar, a top-rated bar in the area. For other recommendations, Valentina provides a perfect setting for rounding out your night with style and great drinks. Likewise, Caffe Dal Perugino offers a memorable night with diverse drink options and excellent service.
Get a good night's sleep and look forward to another great day on the road in Italy!
Day 9
- Perugia
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Drive 4 km, 1 hour 2 min
- Chiesa di San Michele Arcangelo
- Acquedotto medievale di Perugia
- Perugia Sotterranea Accesso
- Piazza IV Novembre
- Rocca Paolina
- National Archaeological Museum of Umbria
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On day 9 of your road trip, you will have an entire day to explore Perugia. You’ll stay in Perugia for 1 night and discover all the best things to see and do in the area.
Today’s itinerary in Perugia covers several incredible sights, including a church, a historical landmark, a cave system, a public square, a museum and much more! Start your adventure at Chiesa Di San Michele Arcangelo. This locally appreciated church is a place that is appreciated by travelers and locals alike. Next, immerse yourself in the breathtaking wonders of Acquedotto Medievale Di Perugia, a must-see historical landmark in the city.
Consider stopping for a small bite to eat or a drink at a local eatery to keep your energy going. When you’re ready, continue your discovery with a visit to Perugia Sotterranea Accesso. This intriguing cave system offers an enriching experience. For a change of pace, head to Piazza Iv Novembre, where you can take in majestic features. Conclude your self-guided sightseeing tour with a visit to Rocca Paolina and National Archaeological Museum Of Umbria. These sights offer a fulfilling end to a perfect day.
Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.
After a day of adventure, treat yourself to an exquisite dinner at one of Perugia's best restaurants.
Make sure to reserve a table at La Taverna, an iconic dining spot in Perugia. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Ristorante del Sole, a popular restaurant in Perugia. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Al Mangiar Bene, a hidden gem nestled in Perugia. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.
To truly maximize your evening out, consider visiting Caffè Fortebraccio after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to Caffe Del Banco, another bar with an inviting ambiance. Similarly, Dempsey's Perugia also offers a great atmosphere, ensuring a night filled with enjoyment and relaxation.
Savor another day of unforgettable experiences in Italy!
Day 10
- Perugia
- Pescara
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Drive 333 km, 6 hours 1 min
- Gran Sasso e Monti della Laga National Park
- Cascata del Rio Arno
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Dive into day 10 of your remarkable road trip in Italy. Today you will explore Fano Adriano and Pietracamela, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Pescara. You’ll stay here for 1 night.
Perugia is brimming with adventures. Today’s wonderful stops include a national park and a waterfall. Begin your sightseeing adventure at the well-known Gran Sasso E Monti Della Laga National Park and allow yourself time to explore. Just a short distance away you'll find your next stop, Cascata Del Rio Arno, an eye-catching waterfall that draws visitors from far and near.
When you’re done exploring for the day, you’ll drive to your hotel in Pescara. Check in and spend some time relaxing before you head out to tour the city.
As dinnertime approaches, it's time to head out for a bite to eat in Pescara. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.
Enjoy a delicious meal at Ciacco, a highly-rated dining destination in Pescara. If you're eager to try something different, consider Bar Sara, another top spot with a tantalizing menu. You might also want to secure a reservation at Ristorante Franco. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Pescara this evening.
After your delicious meal, get a taste of the vibrant nightlife with a visit to Bar Napoli, known for its inviting atmosphere. Bar Supermarket is another great option if you’re looking for a place to get the night started. Similarly, Post Bar provides a great setting to enjoy the night away.
Savor another day of unforgettable experiences in Italy!
Day 11
- Pescara - Departure day
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- Parrocchia Spirito Santo
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Day 11 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Pescara before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.
If you're up for some more sightseeing, begin at Parrocchia Spirito Santo. This increasingly popular church is a popular place to see in the city.
Maximize your last day in Italy and go on a shopping spree in Pescara’s shopping center, the lively Centro Commerciale Pescara Porta Nuova. Browse for souvenirs to remind you of your wonderful journey in Italy.
Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Pescara.
If you're in the mood to try something new, consider La Taverna Antica, another top spot with a mouthwatering menu.
You’ll then say farewell to Pescara. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!
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