11-Day Italy Self-Drive Road Trip With Itinerary from Rome to Florence, San Gimignano, and La Spezia

1 / 53
Photo of piazza de spagna in Rome, Italy.
Perfect travel plans
Everything included
Fully customizable

Description

Included

Flights
Hotel
Select dates
Car rental
Select dates
Tours & tickets
Select dates
Travel plan
From A to Z
Travel agent
24/7 fast service

Description

Explore the best of Italy on a remarkable 11-day road trip! Combine exploration with relaxation on a self-drive tour featuring Rome, Florence, Pisa, Lucca, Siena, San Gimignano, Gaiole in Chianti, Castelnuovo Berardenga, Riomaggiore, La Spezia, Manarola, Corniglia, Vernazza, and Orvieto.

This perfectly planned road trip itinerary takes you through some of the best places to see in Italy. You will spend 3 nights in Rome, 3 nights in Florence, 2 nights in San Gimignano, and 2 nights in La Spezia. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Rome, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Trevi Fountain and Colosseum are just a couple of the bucket-list attractions that await your discovery.

As you hit the open road and drive through Rome, Florence, Pisa, Lucca, Siena, San Gimignano, Gaiole in Chianti, Castelnuovo Berardenga, Riomaggiore, La Spezia, Manarola, Corniglia, Vernazza, and Orvieto, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.

Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!

Read more

Travel details

Set your travel details to find the best price

Flights

Round trip
Round trip
Travel dates

Travelers

Rooms

Flights

Compare and choose from the best flights to Rome

Car

Choose from the best car rental deals or see all options

Driver’s age is 30 - 65
I live in
Pick-up: 10:00
Drop-off: 10:00

Personalize your itinerary

Customize tours under each day and destination

Day 1

Day 1

  • Rome - Arrival day
  • More
  • Trevi Fountain
  • More

Your road trip adventure in Italy begins as soon as you reach Rome and pick up your car. You’ll stay here for 2 nights and explore what to see in Rome, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.

Rome is a beautiful city with plenty to discover. Taking a stroll in the city center is a great alternative. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

When you're ready for some downtime, make your way to your chosen hotel. Check-in typically starts between 2 and 4 PM in Rome. Make yourself at home and unwind before heading out again.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Rome, it's often a good idea to reserve a table in advance.

Raise a toast to the start of your 11-day road trip in Italy!

Read more
Day 2

Day 2

  • Rome
  • More

Drive 5 km, 1 hour 6 min

  • Colosseum
  • Roman Forum
  • Pantheon
  • Piazza Navona
  • Campo de' Fiori
  • Trastevere
  • More

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

Indulge in a memorable dining experience at one of Rome's most popular restaurants, and connect with friendly locals for a true cultural experience.

Raise your glass to another unforgettable day in Italy!

Read more
Day 3

Day 3

  • Rome
  • Florence
  • More

Drive 281 km, 3 hours 45 min

  • piazzale Michelangelo
  • Basilica of Santa Croce in Florence
  • Uffizi Gallery
  • Ponte Vecchio
  • piazza della Signoria
  • More

On day 3 of your road trip in Italy, your travel plans include 1 stop at the most scenic, wondrous, and interesting places in the region. Florence are on today's agenda. In the evening, you’ll end up in Florence, where you will stay for 3 nights.

When you’re done exploring for the day, you’ll drive to your hotel in Florence. Check in and relax before you head out to tour the city.

After a day of adventure, treat yourself to an exquisite dinner at one of Florence's best restaurants.

Say good night to Florence and look forward to another great day of your road trip in Italy!

Read more
Day 4

Day 4

  • Florence
  • More

Drive 4 km, 1 hour 3 min

  • Palazzo Pitti
  • Cathedral of Santa Maria del Fiore
  • Galleria dell'Accademia
  • Central Market
  • Basilica of Santa Maria Novella
  • Oltrarno
  • More

You have 2 nights left in Florence. Take the opportunity to experience more of the best attractions and activities in the city.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Florence. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Say good night to Florence and look forward to another great day of your road trip in Italy!

Read more
Day 5

Day 5

  • Florence
  • More

Drive 198 km, 3 hours 9 min

  • Leaning Tower of Pisa
  • Piazza del Duomo, Pisa
  • Pisa Cathedral
  • Porta San Pietro
  • Walls of Lucca
  • Piazza Napoleone
  • More

On day 5 of your road trip, you'll get the chance to experience Pisa and Lucca. At the end of the day, you'll drive back to Florence, where you still have 1 night left to stay.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Florence.

After a day of adventure, treat yourself to an exquisite dinner at one of Florence's best restaurants.

Raise your glass to another unforgettable day in Italy!

Read more
Day 6

Day 6

  • Florence
  • San Gimignano
  • More

Drive 120 km, 2 hours 12 min

  • Siena Cathedral
  • piazza del Campo
  • Tower of Mangia
  • Porta San Giovanni
  • Town Hall, Picture Gallery and Great Tower
  • Piazza del Duomo, San Gimignano
  • More

Dive into day 6 of your remarkable road trip in Italy. Today you'll explore 2 destinations, including Siena and San Gimignano. At the end of the day, you’ll unwind at one of the finest accommodations in San Gimignano, where you'll spend 2 nights.

Throughout the day, make sure to take breaks to appreciate the surroundings.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in San Gimignano. San Gimignano offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in San Gimignano, it's often a good idea to reserve a table in advance.

Savor another day of unforgettable experiences in Italy!

Read more
Day 7

Day 7

  • San Gimignano
  • More

Drive 136 km, 2 hours 53 min

  • Capannelle
  • Castello di Brolio
  • Fèlsina S.P.A.
  • More

On day 7 of your road trip, you’ll start and end your day in San Gimignano, where you have 1 night left to stay.

When you’re done exploring for the day, you’ll return to San Gimignano and your accommodation.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in San Gimignano. Enjoy a relaxing evening as you savor delicious local cuisine.

Raise your glass and celebrate another amazing day of your road trip in Italy!

Read more
Day 8

Day 8

  • San Gimignano
  • La Spezia
  • More

Drive 184 km, 3 hours 6 min

  • Church of San Giovanni Battista of Riomaggiore
  • Riomaggiore
  • Castle of Riomaggiore
  • More

On day 8 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, including Riomaggiore. When you’re not sightseeing, take time to relax at your chosen hotel in La Spezia, where you’ll be staying for 2 nights.

At the end of the day, you will drive to La Spezia, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in La Spezia. Enjoy a relaxing evening as you savor delicious local cuisine.

Take some time to reflect on your day and savor another beautiful night in Italy.

Read more
Day 9

Day 9

  • La Spezia
  • More

Drive 57 km, 2 hours 3 min

  • Manarola Overlook Viewpoint
  • Chiesa di San Lorenzo
  • Cinque Terre National Park
  • Church of St. Margaret of Antioch
  • Ruins of Doria Tower
  • More

Greet day 9 of your road trip in Italy with a smile and start your day with a hearty breakfast. You have 1 night to stay in La Spezia, so get ready to make the most of your time in the region. On the agenda for this day, you’ll find only the best things to see and do in Manarola, Corniglia, and Vernazza.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in La Spezia.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in La Spezia. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Say good night to La Spezia and look forward to another great day of your road trip in Italy!

Read more
Day 10

Day 10

  • La Spezia
  • Rome
  • More

Drive 437 km, 5 hours 29 min

  • Well of St Patrick
  • Orvieto Cathedral
  • Museo dell'Opera del Duomo
  • Orvieto subterranea
  • Torre del Moro Orvieto
  • Pozzo della Cava
  • More

Experience an unparalleled adventure on day 10 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 place, which are Orvieto. At the end of the day, you will retreat to the hotel of your choice in Rome, where will spend 1 night.

Whether you decide to get entrance tickets for all attractions or you prefer admiring from a distance, amazing experiences await on this day in La Spezia.

When you’re done exploring for the day, you’ll drive to your hotel in Rome. Check in and relax before you head out to tour the city.

Rome is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Rome.

Celebrate another amazing day of your road trip adventure in Italy!

Read more
Day 11

Day 11

  • Rome - Departure day
  • More
  • Palatine Hill
  • More

Day 11 of your road trip in Italy is your departure day. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!

Read more

How it works

Book your journey with Europe’s biggest travel platform—expert itineraries, instant confirmation, and full flexibility with 24/7 support.

Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

We guarantee

Your trip is protected, personalized, and priced right. No surprises, no stress.

Similar travel packages

Discover other popular vacations in Italy

Link to appstore phone
Install Europe’s biggest travel app

Download Europe’s biggest travel marketplace to your phone to manage your entire trip in one place

Scan this QR code with your phone camera and press the link that appears to add Europe’s biggest travel marketplace into your pocket. Enter your phone number or email address to receive an SMS or email with the download link.