11-Day Italy Self-Drive Road Trip With Itinerary from Rome traveling north to Florence, Venice, and La Spezia

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Photo of piazza de spagna in Rome, Italy.
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Experience the freedom of the open road in Italy as you embark on an unforgettable 11-day road trip! This experience caters to every traveler, featuring destinations like Rome, Orvieto, Florence, Pisa, Lucca, Venice, Riomaggiore, Manarola, and La Spezia.

This perfectly planned road trip itinerary in Italy takes you through some of the best places to see in the country. You will spend 4 nights in Rome, 3 nights in Florence, 2 nights in Venice, and 1 night in La Spezia. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Rome, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Trevi Fountain and Colosseum are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Pantheon, learn more about the unique Piazza Navona, and immerse yourself in the vibrant atmosphere of Piazza San Marco.

As you hit the open road and drive through Rome, Orvieto, Florence, Pisa, Lucca, Venice, Riomaggiore, Manarola, and La Spezia, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.

Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!

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Driver’s age is 30 - 65
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Itinerary summary

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Days
Destination
Attractions
Overnight
Day
City & Overnight
Attractions
Palatine Hill
Trevi FountainSpanish StepsCastel Sant'AngeloSistine ChapelSt Peter's BasilicaVatican Museums
Villa BorgheseColosseumRoman ForumCampo de' FioriPiazza Navona
Well of St PatrickBasilica of Santa Croce in FlorenceUffizi GalleryPonte Vecchiopiazza della Signoria
Central MarketGiotto's Bell TowerCathedral of Santa Maria del FioreGalleria dell'Accademiapiazzale MichelangeloAbbazia di San Miniato al Monte
Piazza del Duomo, PisaPisa CathedralLeaning Tower of PisaWalls of LuccaPiazza dell'Anfiteatro

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Day 1

Day 1

  • Rome - Arrival day
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  • Palatine Hill
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Welcome to Rome, the perfect starting point for your road trip in Italy! Pick up your rental car and let the adventure begin. You will spend 3 nights immersing yourself in Rome's charm before embarking on the next leg of your journey.

Rome is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Palatine Hill, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

As afternoon approaches, head to your chosen hotel in Rome. Check-in typically starts around 2 to 4 PM at hotels in Italy. We recommend staying at a hotel in a central location for easy access to the best attractions, restaurants, and bars in the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Rome, it's often a good idea to reserve a table in advance.

Treat yourself to a delightful dinner at La Bottega Roma, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Pasta In Corso? It's another excellent option with a diverse menu. Consider reserving a table at Trattoria Vecchia Roma as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Rome.

After savoring a delicious meal, step into the vibrant nightlife at La Botticella Of Poggi Giovanni, where the evening is just getting started. In the same way, Almalu Trastevere offers a unique charm perfect for experiencing the local bar scene in Rome. Bar Viminale Di Pepi Maurilio is another top-recommended bar that is sure to get you into the mood for some dancing and celebrating.

Raise a toast to the start of your 11-day road trip in Italy!

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Day 2

Day 2

  • Rome
  • More

Drive 15 km, 1 hour 40 min

  • Trevi Fountain
  • Spanish Steps
  • Castel Sant'Angelo
  • Sistine Chapel
  • St Peter's Basilica
  • Vatican Museums
  • More

At the end of the day, you'll drive back to Rome, where you'll stay for 2 nights more.

Start your day at Trevi Fountain. This grand monument is an iconic place to see in Rome. Then, wander over to Spanish Steps. If enchanting sites excite you, this public square will be right up your alley. Nearby, you’ll also find Castel Sant'angelo. This awe-inspiring castle is a favorite among visitors.

Rome offers plenty to explore, ensuring every moment of your visit is filled with excitement and discovery. If you're up for more, Sistine Chapel is an extraordinary spot in the city that will captivate you with its unique charm. Take a moment to appreciate the fascinating details of this globally renowned major basilica. Wrap up your self-guided tour of Rome's top attractions with a visit to Vatican Museums.

When you’re done exploring for the day, you’ll return to Rome and your accommodation.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Rome. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Treat yourself to a delicious dinner at RomAntica, an excellent option for tonight's dining. Looking for something different? Coso Ristorante offers a tantalizing alternative with its diverse menu. And don’t miss DEROMA - Farine Romane. With its reputation for pleasing customers, it’s a fantastic choice for tonight in Rome.

Continue your lively evening at Sant' Eustachio Caffè, a perfect place for winding down or revving up the night, depending on which mood you’re in. Yellowsquare Rome is another excellent bar that offers a great selection of drinks to suit any mood. If you prefer to go somewhere else, Caffè Portofino ensures a night out tailored to your taste.

Say good night to Rome and look forward to another great day of your road trip in Italy!

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Day 3

Day 3

  • Rome
  • More

Drive 11 km, 1 hour 21 min

  • Villa Borghese
  • Colosseum
  • Roman Forum
  • Campo de' Fiori
  • Piazza Navona
  • More

Day 3 of your road trip will take you to the best attractions Rome has to offer. Cherish the 1 night you have left in Rome by discovering the best things there are to see and do in the city.

Immerse yourself in Rome’s rich culture with today's sightseeing itinerary. Start your journey at Villa Borghese. This mesmerizing park is sure to ignite your curiosity. Next, dive into the breathtaking features of Colosseum, a must-visit archeological site in the city.

In between sights, stop by local stores, picturesque photo spots, and small eateries. When you’re ready for your next attraction, proceed to Roman Forum, an iconic archeological site. For a change of scene, check out Campo De' Fiori, known for its romantic features. We also recommend visiting Piazza Navona. This public square is a must for anyone looking to experience the city to the fullest.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

Visit Via del Corso in Rome for an unforgettable shopping experience. Browse unique and stores, each offering delightful surprises. Find unique souvenirs or items to take home. After shopping, explore what Via del Corso has to offer, including attractions, essential services, and vibrant community activities.

Indulge in a memorable dining experience at one of Rome's most popular restaurants, and connect with friendly locals for an authentic adventure.

Treat yourself to a wonderful meal at Hotel de Russie, a top-rated dining spot in Rome. If you're in the mood for something new, try La Taverna Italiana, another premier location with a delectable menu. You might also want to book a table at The Parrot Bar. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Rome.

Keep the excitement of the evening going by visiting a bar or two. The Apartment Bar Roma is an excellent place to start. You could also check out Hotel Hassler Roma, offering a different kind of charm.

Raise your glass and celebrate another amazing day of your road trip in Italy!

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Day 4

Day 4

  • Rome
  • Florence
  • More

Drive 286 km, 3 hours 40 min

  • Well of St Patrick
  • Basilica of Santa Croce in Florence
  • Uffizi Gallery
  • Ponte Vecchio
  • piazza della Signoria
  • More

Experience an unparalleled adventure on day 4 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 2 vibrant destinations - Orvieto and Florence. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Florence. You will spend 3 nights here for some well-deserved relaxation.

Get ready to discover some of the most iconic wonders in Rome, including a monument, a church, an art gallery, a historical landmark, a public square and much more! Start your day at Well Of St. Patrick. This breathtaking monument is a well-known place to see in Rome. Then, wander over to Basilica Of Santa Croce In Florence. If culturally significant sites excite you, this church will be right up your alley. Nearby, you’ll also find Uffizi Gallery. This historic art gallery is a favorite among visitors.

Rome offers plenty to explore, ensuring every moment of your visit is filled with excitement and discovery. If you're up for more, Ponte Vecchio is an iconic spot in the village that will captivate you with its unique charm. When you’re done at the historical landmark, don’t forget to check out the symbolic Piazza Della Signoria. Take a moment to appreciate the fascinating details of this spectacular public square.

When you’re done exploring for the day, you’ll drive to your hotel in Florence. Check in and spend some time relaxing before you head out to tour the city.

As dinnertime approaches, it's time to head out for a bite to eat in Florence. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Dine in style at Ristorante Oliviero 1962, a top recommendation for dinner tonight. Or, for a change of pace, Di Poneta Novoli boasts a menu that's sure to impress. Also, be sure to check out Caffe San Firenze. Known as a local hotspot, it’s a great choice for tonight in Florence.

Explore the vibrant nightlife at Manifattura after your meal, a hub for lively evenings and memorable moments. Or, head to Se·sto On Arno Rooftop Bar for a great selection of flavorful drinks and a charming setting. Furthermore, Il Vinile is perfect for those looking to extend their night with a touch of local flavor.

Relax and recharge in preparation for another adventurous day in Italy!

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Day 5

Day 5

  • Florence
  • More

Drive 11 km, 1 hour 5 min

  • Central Market
  • Giotto's Bell Tower
  • Cathedral of Santa Maria del Fiore
  • Galleria dell'Accademia
  • piazzale Michelangelo
  • Abbazia di San Miniato al Monte
  • More

Day 5 of your road trip across Italy promises a magnificent time exploring Florence. You have 2 nights left in Florence. Take the opportunity to experience more of the best attractions and activities in the city.

Set out on a day brimming with family-friendly attractions, picturesque spots, and wallet-friendly activities. Start at the interesting Central Market, an instagrammable food market in Florence. Next, go to Giotto's Bell Tower.

After visiting Central Market and Giotto's Bell Tower, have a stroll along Florence's streets and take in the local charm. Continue your sightseeing by heading to Cathedral Of Santa Maria Del Fiore. This romantic church offers a unique experience. Galleria Dell'accademia is another noteworthy attraction worthwhile a visit. End your self-guided sightseeing tour on top with a visit to Piazzale Michelangelo, one of the most visually striking places to visit in Florence. If you still have some time left for sightseeing, we also recommend stopping by Abbazia Di San Miniato Al Monte.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Florence. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Enjoy a delicious meal at Ditta Artigianale, a top-rated dining destination in Florence. If you're in the mood to try something new, consider Trattoria Da Burde, another top spot with a mouthwatering menu. You might also want to secure a reservation at Casa Toscana. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Florence this evening.

Round off your dining experience by visiting Bar 50 Rosso, a prime location for a drink. Alternatively, explore the distinctive characteristics of Bitter Bar, a bar catering to every mood and preference. Archea Brewery likewise offers a unique atmosphere, perfect for a memorable night out.

Raise your glass to another unforgettable day in Italy!

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Day 6

Day 6

  • Florence
  • More

Drive 199 km, 3 hours 21 min

  • Piazza del Duomo, Pisa
  • Pisa Cathedral
  • Leaning Tower of Pisa
  • Walls of Lucca
  • Piazza dell'Anfiteatro
  • More

Greet day 6 of your road trip in Italy with a smile and start your day with a hearty breakfast. You will return to Florence for your remaining 1 night in the city later today, but first, it’s time for some exploring! On the agenda for this day, you’ll find only the best things to see and do in Pisa and Lucca.

Immerse yourself in Florence’s rich culture with today's sightseeing itinerary. Start your journey at Piazza Del Duomo, Pisa. This historic public square is sure to ignite your curiosity. Next, dive into the historic features of Pisa Cathedral, a must-visit church in the city.

In between sights, stop by local stores, picturesque photo spots, and small eateries. When you’re ready for your next attraction, proceed to Leaning Tower Of Pisa, a wondrous monument. For a change of scene, check out Mura Di Lucca, known for its enchanting features. We also recommend visiting Piazza Dell'anfiteatro. This public square is a must for anyone looking to experience the city to the fullest.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Florence.

After a day of adventure, treat yourself to an exquisite dinner at one of Florence's best restaurants.

Treat yourself to a wonderful meal at Ristorante Buca Mario, a top-rated dining spot in Florence. If you're in the mood for something new, try Agricola Toscana, another premier location with a delectable menu. You might also want to book a table at Eataly Firenze. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Florence.

If you’re not ready to end the night just yet, Gosh* offers a perfect venue to relax and savor a drink. Similarly, Antico Caffè Del Moro - Art Bar Firenze is well-suited for those looking to unwind in a social setting. Quelo Bar is another excellent spot to enjoy a nightcap after a delightful meal.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in Italy.

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Day 7

Day 7

  • Florence
  • Venice
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Drive 262 km, 3 hours 47 min

  • Bridge of Sighs
  • Doge's Palace
  • St Mark's Basilica
  • St Mark's Campanile
  • Piazza San Marco
  • Teatro La Fenice
  • More

Embark on another extraordinary experience on day 7 of your road trip in Italy. Today, you will make 1 stop and experience some of the highlights of Venice. At the end of the day, you will enjoy the comforts of a top-rated hotel in Venice, which will be your home away from home for 2 nights.

Brace yourself for today’s incredible lineup of attractions in Florence, featuring family-friendly attractions, romantic experiences, and breathtaking views. Start at Bridge Of Sighs, a well-known monument in the city. Then, head to Doge's Palace and soak in the ambiance of this UNESCO world heritage-designated palace.

There are many interesting places to see in Florence, and when you are ready for more, go to St Mark's Basilica. This is one of the city’s most notable history-steeped spots of interest. After exploring the church, visit the underrated St Mark's Campanile. Not far away, you'll also find Piazza San Marco. This public square is an UNESCO world heritage-designated highlight in Florence. Before wrapping up your self-guided sightseeing tour, head to Teatro La Fenice, a locally renowned opera house in the city.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Venice. Venice offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As you explore more of Venice, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Savor the flavors at Bauer Hotel, a top pick for dinner tonight. Alternatively, L'Osteria Le Guglie beckons with its unique menu offerings. Also, consider Corner Pub. With its consistent customer satisfaction, it’s an excellent option for dining in Venice tonight.

Following your dinner, dive into the local bar culture at Al Parlamento. Enjoy this evening's relaxed ambiance with delightful drinks. Alternatively, go to The Caffe Rosso, the perfect place for those looking to experience the best of the nightlife. Similarly, Adagio provides excellent drinks and a great atmosphere, ensuring a memorable night out.

Head back to your accommodation in Venice and get some rest in preparation for another magical day of your road trip in Italy!

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Day 8

Day 8

  • Venice
  • More

Drive 1 km, 22 min

  • Galleria Giorgio Franchetti alla Ca' d'Oro
  • Rialto Bridge
  • Grand Canal
  • Cannaregio
  • More

Day 8 offers a multitude of experiences. You will stay in Venice for 1 night more, offering you enough time to explore at a relaxed pace.

Cannaregio is a neighborhood that stands out as one of the must-see places in Venice. Take a moment to explore its distinct atmosphere, and don’t miss the popular sightseeing spots just a short walk away.

Get ready for a day filled with family-friendly attractions, romantic experiences, and breathtaking views in the charming city of Venice. Your adventure starts at Ca' D'oro, an underrated local hot spot. Another notable attraction to explore is Rialto Bridge. This timeless historical landmark is known for its romantic appeal.

After soaking in the highlights of these sights, take some time to wander Venice's streets and immerse yourself in the local atmosphere. When you're ready to continue your sightseeing adventure, head to Grand Canal. This romantic street offers a fascinating experience that many visitors find memorable.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

After a day of adventure, treat yourself to an exquisite dinner at one of Venice's best restaurants.

Have a fantastic dining experience at Generator Venice, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Nevodi offers an enticing alternative with its varied menu. Additionally, Ristorante La Piazza is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Venice.

If you’re not ready to end the night just yet, Il Mercante offers a perfect venue to relax and savor a drink. Similarly, The Irish Pub Venezia is well-suited for those looking to unwind in a social setting. Ai Stagneri is another excellent spot to enjoy a nightcap after a delightful meal.

Celebrate another amazing day of your road trip adventure in Italy!

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Day 9

Day 9

  • Venice
  • La Spezia
  • More

Drive 393 km, 5 hours 35 min

  • Castle of Riomaggiore
  • Riomaggiore
  • Manarola Overlook Viewpoint
  • More

On day 9 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 2 destinations, Riomaggiore and Manarola. When you’re not sightseeing, take time to relax at your selected hotel in La Spezia, where you’ll be staying for 1 night.

Continue your journey to Manarola Overlook Viewpoint, one of the village’s most beloved spots that you shouldn’t miss.

At the end of the day, you will drive to La Spezia, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

Indulge in a memorable dining experience at one of La Spezia's most popular restaurants, and connect with friendly locals for an authentic adventure.

Treat yourself to a delicious dinner at The Colombaio Park, an excellent option for tonight's dining. With its reputation for pleasing customers, it’s a fantastic choice for tonight in La Spezia.

Relax and reminisce about your day in Italy and look forward to more memorable moments to come!

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Day 10

Day 10

  • La Spezia
  • Rome
  • More

Drive 437 km, 5 hours 16 min

  • Orvieto Cathedral
  • Museo dell'Opera del Duomo
  • Orvieto subterranea
  • Torre del Moro Orvieto
  • Pozzo della Cava
  • More

Dive into day 10 of your remarkable road trip in Italy. Today you will explore Orvieto, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Rome. You’ll stay here for 1 night.

Get ready for a day filled with fun adventures, romantic experiences, and breathtaking views in the charming town of La Spezia. Your adventure starts at Orvieto Cathedral, a captivating local hot spot. Another notable attraction to explore is Museo Dell'opera Del Duomo. This up-and-coming museum is known for its inviting appeal.

After soaking in the highlights of these sights, take some time to wander La Spezia's streets and immerse yourself in the local atmosphere. When you're ready to continue your sightseeing adventure, head to Orvieto Underground. This instagrammable cave system offers a fascinating experience that many visitors find memorable. Torre Del Moro Orvieto is also worth visiting, along with Pozzo Della Cava. These standout landmarks offer unique experiences that add to the day’s enjoyment.

When you’re done exploring for the day, you’ll drive to your hotel in Rome. Check in and spend some time relaxing before you head out to tour the city.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Rome. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Don’t miss out on dining at Sofitel Roma Villa Borghese, a top-rated dining destination in Rome. If you're in the mood to try something new, consider Centro, another top spot with a mouthwatering menu. You might also want to secure a reservation at Ristorante Tema. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Rome this evening.

Take some time to reflect on your day and savor another beautiful night in Italy.

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Day 11

Day 11

  • Rome - Departure day
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  • Pantheon
  • More

Day 11 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Rome before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, begin at Pantheon. This wondrous monument is a popular place to see in the city.

As your final day in Italy unfolds, enjoy a last-minute shopping spree in Rome's best shopping area, Via Condotti. Enjoy finding the perfect gift or keepsake to remind you of your wonderful trip to Italy. Explore high-end stores offering an exquisite selection of luxury items.

Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Rome.

Enjoy a lovely meal at Ristorante Va. Do. , a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Giulia Restaurant is another top choice with a popular menu.

You’ll then say farewell to Rome. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!

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