12-Day Italy Self-Drive Road Trip With Itinerary from Ancona traveling south to Bologna, Florence, Rome, and Pescara

Embark on another extraordinary experience on day 2 of your road trip in Italy. Today, you will make 2 stops and experience some of the highlights of Ancona and Loreto. At the end of the day, you will enjoy the comforts of a top-rated hotel in Bologna, which will be your home away from home for 1 night.

Discover a day packed with fun adventures, scenic views, and picturesque spots in Ancona. Begin your sightseeing with Palazzo Degli Anziani. This worthwhile palace is one of the top attractions in the city. Proceed to Museo Archeologico Nazionale Delle Marche, another must-visit attraction that enhances the city’s allure.

When you’ve had your share of Ancona, prepare for your next destination. Admire the views and listen to some good music as you drive in the direction of Loreto. Your travel time is around 35 min.

Make your way to Sanctuary Of The Holy House Of Loreto, a captivating church that draws attention for its culturally significant features.

At the end of the day, you will drive to Bologna, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you explore more of Bologna, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Begin your culinary exploration in Bologna by securing a reservation at Ahimè. This renowned restaurant holds a Bib Gourmand award and offers an exceptional menu of country cooking cuisine. For another dining delight, visit I Portici, celebrated for its delectable creative and contemporary menu. This acclaimed 1-star Michelin-recipient consistently leaves guests satisfied, making it a must-visit during your holiday. Looking for a different experience? Discover Trattoria di Via Serra, a top local spot known for its tantalizing emilian menu. With a Bib Gourmand recognition, it guarantees an exceptional dining adventure.

Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, Bar Al Bricco D'oro stands out as an excellent choice for a post-dinner cocktail. Alternatively, Bar Freud E Squisito offers an ideal atmosphere to enjoy the pleasures of the night. Osteria Del Sole is also a great option that provides a perfect setting for a relaxing evening.

Savor another day of unforgettable experiences in Italy!

Dive into day 3 of your remarkable road trip in Italy. Today you will explore Bologna and Pisa, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Florence. You’ll stay here for 3 nights.

Set out on a day brimming with family-friendly attractions, scenic views, and photo-friendly spots. Start at the locally renowned Two Towers, a historic monument in Bologna. Next, go to Piazza Maggiore.

When you’re ready to jump back into the car and say goodbye to Bologna, you’ll hit the road in the direction of Pisa. This drive usually takes around 2 hours 15 min. When you arrive, enjoy some sightseeing.

Savor the rest of your day by heading to Knights' Square, a curiosity-inducing public square that draws visitors from near and far. When you're done, continue on to Piazza Del Duomo, Pisa, where you can soak in the picture-perfect surroundings. Next, explore Leaning Tower Of Pisa, yet another wondrous place to see in the area.

After soaking up all the sights of today's itinerary, you'll be ready to hit the road in the direction of your accommodation in Florence. Florence offers plenty of top-rated hotels and other places to stay on any travel budget. Take some time to relax before you head out to explore.

As dinnertime approaches, it's time to head out for a bite to eat in Florence. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Enjoy an outstanding dining experience at Enoteca Pinchiorri, a 3-star Michelin restaurant offering an exceptional italian contemporary menu. Alternatively, if you're in the mood for something different, consider the nearby 2-star Michelin-awardee, Santa Elisabetta, known for its delicious creative and mediterranean cuisine. Another highly-recommended place to eat in Florence is Gucci Osteria da Massimo Bottura, a renowned restaurant with a 1-star Guide Michelin recognition and a delicious italian contemporary and international menu.

Let the evening flow smoothly from dinner to drinks at Manifattura, a top-rated bar in the area. For other recommendations, Se·sto On Arno Rooftop Bar provides a perfect setting for rounding out your night with style and great drinks. Likewise, Il Vinile offers a memorable night with diverse drink options and excellent service.

As the sun sets on another day of adventure, rest up and recharge for the next leg of your road trip in Italy.

At the end of the day, you'll drive back to Florence, where you'll stay for 2 nights more.

Set out on a day brimming with family-friendly attractions, romantic experiences, and breathtaking views. Start at the extraordinary Piazzale Michelangelo, a visually striking observation deck in Florence. Next, go to Galleria Dell'accademia.

After visiting Piazzale Michelangelo and Galleria Dell'accademia, take time to explore Florence's streets and absorb its charm. Continue your sightseeing by heading to Central Market. This visually striking food market offers a unique experience.

Fasten your seatbelt and make your way to your next stop. Siena, home to many well-known sights in the region, is a lovely destination on today’s itinerary. Keep in mind that your travel time from Florence to Siena may take around 1 hour 16 min without traffic disruptions. Upon arrival in Siena, we highly recommend checking out some of the top attractions.

Make your way to Piazza Del Campo, an impressive public square that draws attention for its visually striking features. Spend some time soaking in the atmosphere before continuing to Siena Cathedral, a history-steeped church that stands out in the city.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Florence.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Florence. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Enjoy a lovely dining experience at Ditta Artigianale, a popular restaurant in Florence. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Florence at Trattoria Da Burde, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated Casa Toscana. It’s yet another ideal choice to enhance your time in Florence tonight.

After enjoying a fulfilling meal, continue your evening at Bar 50 Rosso, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, Bitter Bar offers a welcoming atmosphere for easing into the nightlife. Similarly, Archea Brewery provides an excellent environment for a relaxed and enjoyable evening.

As the sun sets on another day of adventure, rest up and recharge for the next leg of your road trip in Italy.

Day 5 offers a multitude of experiences. You will stay in Florence for 1 night more, offering you enough time to explore at a relaxed pace.

Enjoy the perfect balance of relaxation and exploration in Florence today. One of the most timeless attractions included on the itinerary is Ponte Vecchio. This visually striking historical landmark will help you start your sightseeing on top. Then, take a leisurely stroll to Uffizi Gallery and learn what makes this respected art gallery unique.

Throughout the day, make sure to take breaks to appreciate the surroundings. Next up, visit the spectacular Piazza Della Signoria. After exploring the public square, head to Piazza Della Repubblica. This popular public square is a highlight in Florence. Lastly, don’t forget to check out the widely recognized Cathedral Of Santa Maria Del Fiore. Enjoy exploring this incredible church at your own pace.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

As dinnertime approaches, it's time to head out for a bite to eat in Florence. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Make sure to reserve a table at Ristorante Buca Mario, an iconic dining spot in Florence. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Agricola Toscana, a popular restaurant in Florence. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Eataly Firenze, a hidden gem nestled in Florence. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Let the evening flow smoothly from dinner to drinks at Gosh*, a top-rated bar in the area. For other recommendations, Antico Caffè Del Moro - Art Bar Firenze provides a perfect setting for rounding out your night with style and great drinks. Likewise, Quelo Bar offers a memorable night with diverse drink options and excellent service.

Relax and recharge in preparation for another adventurous day in Italy!

On day 6 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 2 destinations, Otricoli and Vatican City. When you’re not sightseeing, take time to relax at your selected hotel in Rome, where you’ll be staying for 4 nights.

Otricoli’s wonders await as you prepare for another journey on the road, leaving the breathtaking surroundings of Florence behind. This drive usually takes around 2 hours 22 min. Otricoli welcomes you with a multitude of unique vacation experiences.

Make your way to Ocriculum Archaeological Park, a frequently visited archeological site that draws attention for its picture-perfect features.

Continue your road trip and head to your next destination, Vatican City, Vatican City. This car ride takes around 1 hour 7 min.

Your self-guided tour starts at Sistine Chapel, a spectacular chapel that is sure to impress. Take in the surroundings and enjoy the freedom of exploring before you continue your journey. When you’re ready, continue to Vatican Museums, a world-famous art museum beloved by locals and tourists alike.

When you’re done exploring for the day, you’ll drive to your hotel in Rome. Check in and spend some time relaxing before you head out to tour the city.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Rome. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Dive into a culinary adventure like no other in Rome by booking a table at La Pergola. This popular restaurant holds 3 Michelin star and offers an exceptional menu of mediterranean and contemporary cuisine. For another culinary dining option, venture to Il Pagliaccio, celebrated for its delectable creative and innovative menu. This acclaimed 2-star Michelin-recipient consistently leaves guests satisfied, ensuring an essential addition to your holiday itinerary. Seeking an alternative? Discover Enoteca La Torre, a top local restaurant known for its tantalizing mediterranean and creative menu. With a 2-star Michelin recognition, it promises an exceptional dining experience not to be missed.

Cap off your dinner by heading to La Botticella Of Poggi Giovanni, ideal for a leisurely evening with a drink in hand. Almalu Trastevere is another bar that offers an enjoyable setting. Similarly, Bar Viminale Di Pepi Maurilio is also a popular place to go on a night out, perfect for relaxing and socializing.

Raise your glass and celebrate another amazing day of your road trip in Italy!

On day 7 of your road trip, you will have an entire day to explore Rome. You’ll stay in Rome for 3 nights and discover all the best things to see and do in the area.

Today's adventure in Rome promises more breathtaking discoveries and enriching experiences! Begin at Villa Borghese. This serene park is a highlight of any visit in the city. Then, enjoy Piazza Del Popolo, another visually striking attraction that never fails to captivate visitors. Next, head over to Spanish Steps, one of the city’s most top-rated attractions, known for its history-steeped features.

If you’re looking for more, spend time soaking in the atmosphere of Piazza Di Spagna. This history-steeped public square is frequented by locals and tourists alike. To complete your memorable day, make sure to visit Basilica Di Santa Maria Maggiore, an interesting church, and take a stroll around the area.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Rome. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Enjoy a delicious meal at RomAntica, a top-rated dining destination in Rome. If you're in the mood to try something new, consider Coso Ristorante, another top spot with a mouthwatering menu. You might also want to secure a reservation at DEROMA - Farine Romane. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Rome this evening.

Cap off your dinner by heading to Sant' Eustachio Caffè, ideal for a leisurely evening with a drink in hand. Yellowsquare Rome is another bar that offers an enjoyable setting. Similarly, Caffè Portofino is also a popular place to go on a night out, perfect for relaxing and socializing.

Get a good night's sleep and look forward to another great day on the road in Italy!

Day 8 of your road trip will take you to the best attractions Rome has to offer. Cherish the 2 nights you have left in Rome by discovering the best things there are to see and do in the city.

Bring your curiosity for today’s adventure around Rome. Some of the city’s most loved attractions await. Trevi Fountain is the perfect place to start. This monument is one of the most world-famous places to visit in Rome. Next, head to Pantheon, a timeless monument, known for its culturally significant features.

In between the sights, don’t hesitate to take small detours to explore local stores and eateries. When you’re ready to continue your adventure, head to Piazza Navona. This noteworthy public square offers a unique experience that is highly recommended. Meanwhile, Campo De' Fiori adds its own distinct charm to your journey. Finish your day with a visit to Castel Sant'angelo, an enchanting castle in Rome.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Rome. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Don’t miss out on dining at Hotel de Russie, a top-rated dining destination in Rome. If you're in the mood to try something new, consider La Taverna Italiana, another top spot with a mouthwatering menu. You might also want to secure a reservation at The Parrot Bar. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Rome this evening.

After savoring a delicious meal, step into the vibrant nightlife at The Apartment Bar Roma, where the evening is just getting started. In the same way, Hotel Hassler Roma offers a unique charm perfect for experiencing the local bar scene in Rome.

Take some time to reflect on your day and savor another beautiful night in Italy.

Day 9 of your road trip across Italy promises a magnificent time exploring Rome. You have 1 night left in Rome. Take the opportunity to experience more of the best attractions and activities in the city.

Get ready to discover some of the most iconic wonders in Rome, including a monument, a public square, and an archeological site. Start your day at Altare Della Patria. This breathtaking monument is a well-known place to see in Rome. Then, wander over to Capitoline Hill. If enchanting sites excite you, this public square will be right up your alley. Nearby, you’ll also find Roman Forum. This UNESCO world heritage-designated archeological site is a favorite among visitors.

Rome offers plenty to explore, ensuring every moment of your visit is filled with excitement and discovery. If you're up for more, Colosseum is an iconic spot in the city that will captivate you with its unique charm. When you’re done at the archeological site, don’t forget to check out the historic Circus Maximus. Take a moment to appreciate the fascinating details of this locally renowned archeological site in Rome.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

After a day of adventure, treat yourself to an exquisite dinner at one of Rome's best restaurants.

Dine in style at Sofitel Roma Villa Borghese, a top recommendation for dinner tonight. Or, for a change of pace, Centro boasts a menu that's sure to impress. Also, be sure to check out Ristorante Tema. Known as a local hotspot, it’s a great choice for tonight in Rome.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in Italy.

On day 10 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Tivoli. In the evening, you’ll end up in Pescara, where you will stay for 1 night.

Set your GPS to Tivoli and hit the road. Expect a journey of approximately 38 min without stops. Soak in the beautiful landscapes as you drive and look forward to exploring your next destination. Tivoli beckons with new experiences!

Begin your journey at Hadrian's Villa and explore the culturally significant features. Next, make your way to Villa D'este, another highlight in the town. When you’re done exploring the palace, continue to Gregorian Bridge, a respected monument. Nearby, you will also find Villa Gregoriana. This locally appreciated park is a top place to see in the area.

At the end of the day, you will drive to Pescara, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Pescara. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Set out on a gastronomic journey in Pescara by reserving a table at Nole. Renowned for its Bib Gourmand award, this restaurant presents an outstanding menu of italian contemporary and italian cuisine. For a different taste, head over to Estrò, renowned for its delectable contemporary and country cooking dishes. This distinguished Bib Gourmand-recipient is a favorite among guests, making it a worthy addition to your holiday plans. Craving more culinary excitement? Explore Taverna 58, a highly rated local gem known for its exquisite from abruzzo and traditional menu. With a Bib Gourmand acclaim, it promises a dining experience you won't want to miss. With its reputation for pleasing customers, it’s a fantastic choice for tonight in Pescara.

Following your dinner, dive into the local bar culture at Posa Caffè Pescara. Enjoy this evening's relaxed ambiance with delightful drinks. Alternatively, go to Bar Mixer, the perfect place for those looking to experience the best of the nightlife. Similarly, Temple Bar Irish Pub provides excellent drinks and a great atmosphere, ensuring a memorable night out.

Relax and recharge in preparation for another adventurous day in Italy!

Experience an unparalleled adventure on day 11 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 3 vibrant destinations - Giulianova, Teramo, and Ascoli Piceno. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Ancona. You will spend 1 night here for some well-deserved relaxation.

Embrace the thrill of the open road as you wave goodbye to Pescara and set your GPS to Giulianova. While on the road, immerse yourself in your favorite road trip tunes or sample the sounds from a local radio station. This car ride usually takes around 49 min. Upon reaching Giulianova, unwind, observe, and explore. The best things to do, see, and eat are waiting for you.

Your self-guided tour starts at Belvedere, a worthwhile public square that is sure to impress. Take in the surroundings and enjoy the freedom of exploring before you continue your journey.

Once you're ready to continue your road trip, it's time to buckle up and drive, eagerly anticipating your arrival in Teramo. This drive usually takes around 26 min, without any stops or traffic disruptions.

Spend your afternoon discovering Santuario Madonna Delle Grazie, a worthwhile church known for its standout features.

Continue your road trip and head to your next destination, Ascoli Piceno. This car ride takes around 51 min.

One of our top recommendations for your sightseeing is Piazza Del Popolo. Spend some time admiring the visually striking features of the public square before you continue to your next stop.

After soaking up all the sights of today's itinerary, you'll be ready to hit the road in the direction of your accommodation in Ancona. Ancona offers plenty of top-rated hotels and other places to stay on any travel budget. Take some time to relax before you head out to explore.

Indulge in a memorable dining experience at one of Ancona's most popular restaurants, and connect with friendly locals for an authentic adventure.

Discover the culinary delights of Ancona by securing a reservation at Sot'Ajarchi. Esteemed for its a Bib Gourmand award, this restaurant offers a remarkable selection of seafood and from the marches cuisine. Alternatively, Bontà delle Marche beckons with its unique menu offerings.

If you’re not ready to end the night just yet, Alla Tazza D'oro offers a perfect venue to relax and savor a drink.

Head back to your accommodation in Ancona and get some rest in preparation for another magical day of your road trip in Italy!