12-Day Italy Self-Drive Road Trip With Itinerary from Ancona traveling south to Florence, Siena, Rome, Naples, and Amalfi

Experience an unparalleled adventure on day 2 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 place, which are Florence. At the end of the day, you will retreat to the hotel of your choice in Florence, where will spend 2 nights.

When you’ve had your share of Ancona, prepare for your next destination. Admire the views and listen to some good music as you drive in the direction of Florence. Your travel time is around 3 hours 18 min.

One of our top recommendations for your sightseeing is Piazzale Michelangelo. Spend some time admiring the history-steeped features of the observation deck before you continue to your next stop. Then, head to Galleria Dell'accademia. This captivating art gallery is a traveler-favorite in the city.

If you're keen to see more, continue to Central Market. Feed your curiosity by learning something new about the food market. Next, take your journey to Brunelleschi's Dome, a curiosity-inducing monument. Conclude your sightseeing at Cathedral Of Santa Maria Del Fiore, known for its majestic features.

When you’re done exploring for the day, you’ll drive to your hotel in Florence. Check in and relax before you head out to tour the city.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Florence. Enjoy a relaxing evening as you savor delicious local cuisine.

Dine in style at Ristorante Oliviero 1962, a top recommendation for dinner tonight. Or, for a change of pace, Di Poneta Novoli boasts a menu that's sure to impress. Also, be sure to check out Caffe San Firenze. Known as a local hotspot, it’s a great choice for tonight in Florence.

After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at Manifattura, a well-loved spot among locals and tourists. Or, head to Se·sto On Arno Rooftop Bar. This bar boasts a welcoming environment that is perfect for winding down. You could also continue your night at Il Vinile, another top-rated place in the area.

As the sun sets, rest up and recharge for the next leg of your road trip in Italy.

On day 3 of your road trip, you will have an entire day to discover what to see in Florence. You’ll stay in Florence for 1 night.

At the top of the list of things to do today is to explore Oltrarno, a neighborhood that captures the true essence of Florence. Take your time to uncover its best sides and enjoy its proximity to many of the area’s best attractions.

Basilica Of Santa Croce In Florence brings Florence's character to life. This culturally significant church is a highlight of any visit in the city. Then, enjoy Piazza Della Signoria, another enchanting attraction that never fails to captivate visitors. Next, head over to Uffizi Gallery, one of the city’s most extraordinary attractions, known for its historic features.

If you’re looking for more, spend time soaking in the atmosphere of Ponte Vecchio. This majestic historical landmark is frequented by locals and tourists alike. To complete your memorable day, make sure to take a stroll around the area.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Florence, it's often a good idea to reserve a table in advance.

Treat yourself to a delightful dinner at Ditta Artigianale, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Trattoria Da Burde? It's another excellent option with a diverse menu. Consider reserving a table at Casa Toscana as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Florence.

After savoring a delicious meal, step into the vibrant nightlife at Bar 50 Rosso, where the evening is just getting started. In the same way, Bitter Bar offers a unique charm perfect for experiencing the local bar scene in Florence. Archea Brewery is another top-recommended bar that is sure to get you into the mood for some dancing and celebrating.

Celebrate another amazing day of your road trip adventure in Italy!

On day 4 of your road trip in Italy, your travel plans include 2 stops at the most scenic, wondrous, and interesting places in the region. Pisa and Lucca are on today's agenda. In the evening, you’ll end up in Siena, where you will stay for 2 nights.

After soaking in Florence’s unique atmosphere, jump into the car with a full heart and drive in the direction of your next destination: Pisa. Expect your car journey to take a minimum of 1 hour 15 min. When you arrive in Pisa, it's time to take a break from the road.

Enjoy sightseeing at your own pace and allow yourself time to explore the beautiful surroundings. Take your self-guided tour to Pisa Cathedral, an increasingly popular church that everyone visiting Pisa should see. Next, head to Piazza Del Duomo, Pisa. This historic public square is one of the most timeless attractions in the region.

If you're keen to see more, don’t miss out on Leaning Tower Of Pisa, a detailed monument popular among locals as well as travelers.

Fasten your seatbelt and make your way to your next stop — Lucca, home to many well-known sights in the region. Keep in mind that your travel time from Pisa to Lucca may take around 32 min without traffic disruptions. Upon arrival in Lucca, we highly recommend checking out some of the top attractions.

Enjoy sightseeing at your own pace and allow yourself time to explore the beautiful surroundings. Take your self-guided tour to Guinigi Tower, a locally appreciated monument that everyone visiting Lucca should see. Next, head to Piazza Dell'anfiteatro. This enchanting public square is one of the most popular attractions in the region.

At the end of the day, you will drive to Siena, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a day of adventure, treat yourself to an exquisite dinner at one of Siena's best restaurants.

Enjoy a lovely meal at Enoteca I Terzi, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Ristorante Tar-Tufo is another top choice with a popular menu. You could also check for a table at Antica Trattoria Papei. As an establishment that consistently gains high praises from customers, it’s an ideal choice in Siena tonight.

Cap off your dinner by heading to Meet Life Cafè, ideal for a leisurely evening with a drink in hand. Maudit Pub is another bar that offers an enjoyable setting. Similarly, Bar Impero Siena is also a popular place to go on a night out, perfect for relaxing and socializing.

Celebrate another amazing day of your road trip adventure in Italy!

On day 5 of your road trip, you'll get the chance to experience Siena and San Gimignano. At the end of the day, you'll drive back to Siena, where you still have 1 night left to stay.

Make time for Piazza Del Campo, an impressive public square that is worthwhile a visit in the city. Nearby, you’ll find Siena Cathedral, enchanting visitors with its symbolic appeal. Continue your exploration at Basilica Of San Domenico. This church is one of the city’s most intriguing spots.

When you’ve had your share of Siena, prepare for your next destination. Admire the views and listen to some good music as you drive in the direction of San Gimignano. Your travel time is around 40 min.

Porta San Giovanni is a curiosity-inducing monument we recommend visiting today. Discover its picture-perfect features before continuing your self-guided tour to Piazza Del Duomo, a romantic public square that’s well-regarded in the area.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Siena.

Siena is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Siena.

Treat yourself to a delightful dinner at Osteria Quattro Venti, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Fischi per Fiaschi? It's another excellent option with a diverse menu. Consider reserving a table at Osteria da Divo as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Siena.

Cap off your dinner by heading to Charlie Mixology Bar Di Aldinucci Riccardo, ideal for a leisurely evening with a drink in hand. Bar Pinacoteca is another bar that offers an enjoyable setting. Similarly, San Paolo Pub is also a popular place to go on a night out, perfect for relaxing and socializing.

Head back to your accommodation in Siena and get some rest to prepare for another magical day of your road trip in Italy.

On day 6 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, including Rome. When you’re not sightseeing, take time to relax at your chosen hotel in Rome, where you’ll be staying for 2 nights.

Fasten your seatbelt and make your way to your next stop — Rome, home to many well-known sights in the region. Keep in mind that your travel time from Siena to Rome may take around 2 hours 42 min without traffic disruptions. Upon arrival in Rome, we highly recommend checking out some of the top attractions.

Colosseum is a timeless archeological site we recommend visiting today. Discover its historic features before continuing your self-guided tour to Roman Forum, a culturally significant archeological site that’s well-regarded in the area.

Next, stop by Trevi Fountain, a romantic monument. While you’re nearby, don’t forget to visit Piazza Navona, a romantic and truly unique public square. End your sightseeing at Pantheon, a timeless monument that’s highly recommended by travelers passing through the city.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Rome. Rome offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

Rome is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Rome.

Treat yourself to a delightful dinner at La Bottega Roma, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Pasta In Corso? It's another excellent option with a diverse menu. Consider reserving a table at Trattoria Vecchia Roma as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Rome.

Let the evening flow smoothly from dinner to drinks at La Botticella Of Poggi Giovanni, a top-rated bar in the area. For other recommendations, Almalu Trastevere provides a perfect setting for rounding out your night with style and great drinks. Likewise, Bar Viminale Di Pepi Maurilio offers a memorable night with diverse drink options and excellent service.

Raise your glass to another unforgettable day in Italy!

On day 7 of your road trip in Italy, you’ll start and end your day in Rome, but spend the day exploring what’s beyond the city. Since you still have 1 night to spend in Rome, there’s no need to rush. Experience Vatican City to the fullest today with this curated day itinerary.

One of the most iconic spots you can visit today is Trastevere. Allow yourself some time to explore this neighborhood and discover its unique quirks. You'll also find many of the best sightseeing spots nearby. You can also explore Monti, a neighborhood that offers a glimpse into local life and culture.

When you’re done exploring for the day, you’ll return to Rome and your accommodation.

Indulge in a memorable dining experience at one of Rome's most popular restaurants, and connect with friendly locals for a true cultural experience.

Enjoy a delicious meal at RomAntica, a top-rated dining destination in Rome. If you're in the mood to try something new, consider Coso Ristorante, another top spot with a mouthwatering menu. You might also want to secure a reservation at DEROMA - Farine Romane. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Rome this evening.

To truly maximize your evening out, consider visiting Sant' Eustachio Caffè after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to Yellowsquare Rome, another bar with an inviting ambiance. Similarly, Caffè Portofino also offers a great atmosphere, ensuring a night filled with enjoyment and relaxation.

Celebrate another amazing day of your road trip adventure in Italy!

Dive into day 8 of your remarkable road trip in Italy. Today you'll explore 1 destination, including Naples. At the end of the day, you’ll unwind at one of the finest accommodations in Naples, where you'll spend 2 nights.

Continue your road trip and head to your next destination, Naples. This car ride takes around 2 hours 27 min.

When you're ready for some sights, head to Naples National Archaeological Museum, a locally renowned museum in Naples. Explore its detailed features at your own pace before you continue your journey to your next attraction, Cappella Sansevero. This notable museum is a top recommendation in the area.

When you’re ready to explore more, Ovo Castle is an excellent choice. Spend some time discovering what some claim to be the most enchanting castle in the region. Next, continue your sightseeing at the extraordinary Piazza Del Plebiscito and discover what makes this public square unique.

When you’re done exploring for the day, you’ll drive to your hotel in Naples. Check in and relax before you head out to tour the city.

Indulge in a memorable dining experience at one of Naples's most popular restaurants, and connect with friendly locals for a true cultural experience.

Don’t miss out on dining at L'Oca Nera Irish Pub, a top-rated dining destination in Naples. If you're in the mood to try something new, consider Mimì alla Ferrovia, another top spot with a mouthwatering menu. You might also want to secure a reservation at Spuzzulè Winebar. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Naples this evening.

Unwind after your meal by stepping into Happening Cocktail Bar. This venue is celebrated for its extensive drink selections and cozy vibes. Alternatively, Shanti Art Musik Bar offers a dynamic and energetic atmosphere for a glass or two. Don’t overlook Gran Caffè Gambrinus, another top-rated bar in the area.

Take some time to reflect on your day and savor another beautiful night in Italy.

On day 9 of your road trip, you’ll start and end your day in Naples, where you have 1 night left to stay.

As you explore Pompei’s charming streets, take in the lively atmosphere and get to know the character of the town.

When you’ve had your share of Naples, prepare for your next destination. Admire the views and listen to some good music as you drive in the direction of Pompei. Your travel time is around 34 min.

For a more meaningful self-guided tour of the town's best attractions, visit Amphitheatre Of Pompeii, a popular archeological site that is sure to impress. Take in the surroundings and enjoy the freedom of exploring at your own pace before you continue your journey. Next, head to Teatro Grande and admire its picture-perfect features.

When you’re ready, continue to Lupanare Di Pompei, an often recommended archeological site beloved by locals and tourists alike. Don't miss out on Basilica, another highlight of the area that promises a memorable visit. Not far away, you’ll also find Archaeological Park Of Pompeii, a historic place to see that you won’t regret spending some extra time discovering.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Naples.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Naples. Enjoy a relaxing evening as you savor delicious local cuisine.

Treat yourself to a delicious dinner at Antica Pizzeria Di Matteo, an excellent option for tonight's dining. Looking for something different? Mercure Napoli Centro Angioino offers a tantalizing alternative with its diverse menu. And don’t miss La Lazzara Trattoria e Pizzeria. Known for great service, it’s a fantastic choice for tonight in Naples.

After savoring a delicious meal, step into the vibrant nightlife at Archivio Storico - Cocktail Bar & Wonderfood, where the evening is just getting started. In the same way, Archeobar offers a unique charm perfect for experiencing the local bar scene in Naples. Babette Pub is another top-recommended bar that is sure to get you into the mood for some dancing and celebrating.

Raise your glass and celebrate another amazing day of your road trip in Italy!

Your itinerary for day 10 of your road trip in Italy includes 3 stops and features some of the highlights of Positano, Atrani, and Amalfi. At the end of the day, enjoy the comforts of a top-rated hotel in Amalfi, where you'll spend 1 night.

Set your GPS to Positano and hit the road. Expect a journey of approximately 1 hour 27 min without stops. Soak in the beautiful landscapes as you drive and look forward to exploring your next destination. Positano beckons with new experiences!

For a more meaningful self-guided tour of the village's best attractions, visit Costiera Amalfitana Positano, an increasingly popular beach that is sure to impress. Take in the surroundings and enjoy the freedom of exploring at your own pace before you continue your journey.

When you’ve had your share of Positano, prepare for your next destination. Admire the views and listen to some good music as you drive in the direction of Atrani. Your travel time is around 43 min.

When you're ready for some sights, head to Collegiate Santa Maria Maddalena, an underrated church in Atrani. Explore its majestic features at your own pace before you continue your journey.

Set your GPS to Amalfi and hit the road. Soak in the beautiful landscapes as you drive and look forward to exploring your next destination. Amalfi beckons with new experiences!

Enjoy sightseeing at your own pace and allow yourself time to explore the beautiful surroundings. Take your self-guided tour to Amalfi Coast, an extraordinary coast that everyone visiting Amalfi should see. Next, head to Saint Andrew's Fountain Amalfi. This respected monument is one of the most underrated attractions in the region.

If you're keen to see more, don’t miss out on Antico Arsenale Della Repubblica Di Amalfi, a historic museum popular among locals as well as travelers.

At the end of the day, you will drive to Amalfi, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Amalfi. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Savor the flavors at Pasticceria Pansa Amalfi, a top pick for dinner tonight. Alternatively, Grand Hotel Excelsior Amalfi beckons with its unique menu offerings. Also, consider Lido Azzurro. With its consistent customer satisfaction, it’s an excellent option for dining in Amalfi tonight.

After enjoying a fulfilling meal, continue your evening at Bar Della Valle, ideal for those looking to unwind with a drink in a comfortable setting.

Relax and recharge in preparation for another adventurous day in Italy!

Experience an unparalleled adventure on day 11 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 3 places, which are Ravello, Castiglione, and Minori. At the end of the day, you will retreat to the hotel of your choice in Ancona, where will spend 1 night.

Embrace the thrill of the open road as you wave goodbye to Amalfi and set your GPS to Ravello. While on the road, immerse yourself in your favorite road trip tunes or sample the sounds from a local radio station. This car ride usually takes around 18 min. Upon reaching Ravello, unwind, observe, and explore. The best things to do, see, and eat are waiting for you.

Spend your afternoon discovering Giardini Principessa Di Piemonte, a worthwhile park known for its instagrammable features. Next, continue your sightseeing at Villa Rufolo, an interesting historical landmark.

Once you're ready to continue your road trip, it's time to buckle up and drive, eagerly anticipating your arrival in Minori. This drive usually takes around 17 min, without any stops or traffic disruptions.

Set out on a self-guided sightseeing tour at Villa Cimbrone Gardens and explore the enchanting features.

Once you're ready to continue your road trip, it's time to buckle up and drive, eagerly anticipating your arrival in Minori. This drive usually takes around 17 min, without any stops or traffic disruptions.

Spend your afternoon discovering Path Of The Lemons, a beloved hiking area known for its awe-inspiring features.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Ancona. Ancona offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Ancona, it's often a good idea to reserve a table in advance.

Treat yourself to a wonderful meal at Amarcord, a top-rated dining spot in Ancona. If you're in the mood for something new, try Bontà delle Marche, another premier location with a delectable menu. You might also want to book a table at Ristorante Pizzeria Da Romano. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Ancona.

Extend your evening after a delightful meal by visiting Alla Tazza D'oro, which offers the perfect atmosphere for a night out.

Relax and look forward to more memorable moments to come!