12-Day Italy Road Trip from Florence to Rome, Siena, Venice, Verona, Milan, and Genoa and surrounding area

Welcome to Florence, the perfect starting point for your road trip in Italy! Pick up your rental car and let the adventure begin. You will spend 2 nights immersing yourself in Florence's charm before embarking on the next leg of your journey.

Florence is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Piazza Della Signoria or taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Make your way to your chosen hotel. Check-in typically starts between 2 and 4 PM in Florence. Make yourself at home and enjoy some downtime before heading out again.

As dinnertime approaches, it's time to head out for a bite to eat in Florence. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Make sure to reserve a table at Ristorante Oliviero 1962, an iconic dining spot in Florence. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Caffe San Firenze, a popular restaurant in Florence. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Ditta Artigianale, a hidden gem nestled in Florence. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Cap off your dinner by heading to Manifattura, ideal for a leisurely evening with a drink in hand. Se·sto On Arno Rooftop Bar is another bar that offers an enjoyable setting. Similarly, Archea Brewery is also a popular place to go on a night out, perfect for relaxing and socializing.

Raise a toast to the start of your 12-day road trip in Italy!

On day 2 of your road trip, you will have an entire day to explore Florence. You’ll stay in Florence for 1 night and discover all the best things to see and do in the area.

Drop by the renowned Galleria Dell'accademia. This popular national museum has been rated an average of 4.6 out of 5 stars by 34,429 visitors. Based on recent data, this attraction is visited by more than 1,719,645 travelers every year.

Another unforgettable place to experience is Cathedral Of Santa Maria Del Fiore. Rated 4.8 out of 5 stars by 76,359 visitors, this church deserves a spot on today's sightseeing itinerary.

We also recommend a visit to Giotto's Bell Tower. This sightseeing destination has been rated an average of 4.8 out of 5 stars in 4,849 reviews.

Another favorite attraction in the area is The Boboli Gardens. This park and popular place of interest enjoys a rating of 4.2 out of 5 stars from 25,341 local and international travelers.

If you’re keen to explore even more, then consider a visit to Central Market. With an average rating of 4.4 out of 5 stars from 43,100 travelers, this point of interest is an attraction many avid travelers highly recommend visiting while in Florence.

To do something one-of-a-kind on this day of your trip, you can join a tour. You can discover all of the most fun and eye-opening experiences in your destination below and secure your spot here.

After a day of adventure, treat yourself to an exquisite dinner at one of Florence's best restaurants.

Begin your culinary exploration in Florence by securing a reservation at Enoteca Pinchiorri. This renowned restaurant holds 3 Michelin star and offers an exceptional menu of italian contemporary cuisine. For another dining delight, visit Santa Elisabetta, celebrated for its delectable creative, and mediterranean menu. This acclaimed 2-star Michelin-recipient consistently leaves guests satisfied, making it a must-visit during your holiday. Looking for a different experience? Discover Gucci Osteria da Massimo Bottura, a top local spot known for its tantalizing italian contemporary, and international menu. With a 1-star Michelin recognition, it guarantees an exceptional dining adventure.

Relax and reminisce about your day in Italy and look forward to more memorable moments to come!

Embark on another extraordinary experience on day 3 of your road trip in Italy. Today, you will make 1 stop and experience some of the highlights of Florence. At the end of the day, you will enjoy the comforts of a top-rated hotel in Rome, which will be your home away from home for 3 nights.

Drop by the renowned Basilica Of Santa Croce In Florence. This popular church has been rated an average of 4.7 out of 5 stars by 28,544 visitors.

Another unforgettable place to experience is Piazzale Michelangelo. Rated 4.8 out of 5 stars by 77,744 visitors, this square deserves a spot on today's sightseeing itinerary.

We also recommend a visit to Basilica Di Santa Maria Novella, Firenze (fi). This archives has been rated an average of 4.7 out of 5 stars in 23,075 reviews.

Another favorite attraction in the area is Tower Of San Niccolò. This city gate and popular place of interest enjoys a rating of 4.6 out of 5 stars from 712 local and international travelers.

At the end of the day, you will drive to Rome, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a day of adventure, treat yourself to an exquisite dinner at one of Rome's best restaurants.

Start your culinary exploration in Rome by securing a reservation at La Pergola. This renowned restaurant holds 3 Michelin star and offers an exceptional menu of mediterranean, and contemporary cuisine. For another dining delight, visit Il Pagliaccio, celebrated for its delectable creative, and innovative menu. This acclaimed 2-star Michelin-recipient consistently leaves guests satisfied, making it a must-visit during your holiday. Looking for a different experience? Discover Enoteca La Torre, a top local spot known for its tantalizing mediterranean, and creative menu. With a 2-star Michelin recognition, it guarantees an exceptional dining adventure.

Continue your evening by exploring the vibrant nightlife scene at La Botticella Of Poggi Giovanni, a prime destination for a thrilling night out. Also, don’t forget to check out Sant' Eustachio Caffè, a bar that offers unique local touches. Likewise, Caffè Portofino provides an excellent alternative for a fun evening.

Savor another day of unforgettable experiences in Italy!

Day 4 of your road trip will take you to the best attractions Rome has to offer. Cherish the 2 nights you have left in Rome by discovering the best things there are to see and do in the city.

Start your sightseeing with a visit to Villa Borghese. This urban zone of rome is a popular stop on travelers’ itineraries in Rome, with an average rating of 4.6 out of 5 stars by 69,749 visitors.

Piazza Del Popolo is another popular place of interest you can visit today. The average rating of 4.6 out of 5 stars from 89,807 reviews gives you an idea of other visitors’ experience at this attraction.

If it’s still bright and early, make your way to Pantheon. Visitors have rated this roman temple an average of 4.8 out of 5 stars in 189,682 reviews. Pantheon receives around 30,000,000 visitors every year.

Piazza Navona is another unique site you can experience today. This attraction is a square rated an average of 4.7 out of 5 stars in 158,771 reviews.

Make your way to the fantastic Castel Sant'angelo, perhaps the most famous museum in Rome. This attraction welcomes around 918,591 visitors annually and is rated 4.7 out of 5 stars by 72,431 travelers.

There are plenty of experiences you can choose from in Italy that will add excitement to your vacation. When you’re keen to discover what else Rome has in store for you, use this day to go on a tour. Scroll down and select tours and activities to include on your itinerary for the day.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Rome. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Enjoy a delicious meal at DEROMA - Farine Romane, a top-rated dining destination in Rome. If you're in the mood to try something new, consider La Taverna Italiana, another top spot with a mouthwatering menu. You might also want to secure a reservation at Centro. With a reputation for consistently satisfied customers, it’s a perfect choice to enhance your stay in Rome this evening.

Continue your lively evening at The Apartment Bar Roma, a perfect place for winding down or revving up the night, depending on which mood you’re in. Hotel Hassler Roma is another excellent bar that offers a great selection of drinks to suit any mood.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in Italy.

Day 5 offers a multitude of experiences. You will stay in Rome for 1 night more, offering you enough time to explore at a relaxed pace.

Kick off the day at Spanish Steps, a top pick for today’s sightseeing. This monumental staircase is rated an average of 4.5 out of 5 stars in 57,211 reviews.

Today is also your chance to visit Piazza Di Spagna. Piazza Di Spagna is a square with an average rating of 4.7 out of 5 stars from 113,658 reviews.

Trevi Fountain is another top attraction we highly recommend you visit today. This sculpture is rated an average of 4.8 out of 5 stars by 343,494 visitors.

Beyond the attractions mentioned above, you also have the opportunity to visit Roman Forum. This square is rated an average of 4.7 out of 5 stars by 114,450 visitors.

Lastly, don’t miss out on Colosseum, a famous roman amphitheatre in Rome. This attraction welcomes 7,400,000 visitors annually and is rated an average of 4.7 out of 5 stars by 328,821 travelers.

One of the most unique ways of discovering what else Rome has to offer is by going on a top-rated tour. Be sure to check out all the experiences Rome offers and add your favorites to your Italy travel package below.

Indulge in a memorable dining experience at one of Rome's most popular restaurants, and connect with friendly locals for an authentic adventure.

Have a fantastic dining experience at Ristorante Tema, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Maccheroni offers an enticing alternative with its varied menu. Additionally, RoYaL Art Cafè Roma is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Rome.

Head back to your accommodation in Rome and get some rest in preparation for another magical day of your road trip in Italy!

Dive into day 6 of your remarkable road trip in Italy. Today you will explore Rome, and Vatican City, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Siena. You’ll stay here for 1 night.

An excellent attraction to start your day with is Altare Della Patria. This architectural structure typically receives around 1,683,070 visitors every year and is rated an average of 4.8 out of 5 stars in 49,843 reviews.

Vatican City’s wonders await as you prepare for another journey on the road, leaving the breathtaking surroundings of Rome behind. This drive usually takes around 11 min. Vatican City welcomes you with a multitude of unique vacation experiences.

Make St. Peter's Basilica one of your first sightseeing stops in Vatican City. Rated an average of 4.8 out of 5 stars by 131,043 travelers, a visit to this local attraction makes for a great introduction to the area. This major basilica attracts 11,000,000 visitors every year.

Sistine Chapel is a worthwhile attraction you can visit next. This chapel is a valued place of interest in the area, with an average rating of 4.7 out of 5 stars from 52,083 reviews.

Today is also the perfect opportunity to drop by Vatican Museums. This art museum has been rated an average of 4.6 out of 5 stars by 133,310 visitors. Up to 1,612,530 people travel to this site annually.

After soaking up all the sights of today's itinerary, you'll be ready to hit the road in the direction of your accommodation in Siena. Siena offers plenty of top-rated hotels and other places to stay on any travel budget. Take some time to relax before you head out to explore.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Siena. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Enjoy a delicious meal at Antica Trattoria Papei, a highly-rated dining destination in Siena. If you're eager to try something different, consider Osteria Quattro Venti, another top spot with a tantalizing menu. You might also want to secure a reservation at Osteria da Divo. With a reputation for consistently satisfied customers, it’s an excellent choice to enhance your stay in Siena this evening.

After enjoying a fulfilling meal, continue your evening at Meet Life Cafè, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, Maudit Pub offers a welcoming atmosphere for easing into the nightlife. Similarly, Bar Impero Siena provides an excellent environment for a relaxed and enjoyable evening.

Raise your glass and celebrate another amazing day of your road trip in Italy!

On day 7 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 2 destinations, Siena, and Bologna. When you’re not sightseeing, take time to relax at your selected hotel in Venice, where you’ll be staying for 1 night.

Seize the day by visiting some of the best attractions in the area, like Tower Of Mangia. This extraordinary sightseeing destination has an average rating of 4.6 out of 5 stars from 673 visitors.

Next, make your way to Piazza Del Campo. This square is rated an average of 4.8 out of 5 stars in 64,175 reviews.

While in Siena, we also recommend a visit to Siena Cathedral. This domus has been rated an average of 4.8 out of 5 stars in 21,656 reviews.

Continue your road trip and head to your next destination, Bologna. This car ride takes around 1 hour 56 min.

When you’re ready for some sightseeing, make your way to Ducati Museum. This much-appreciated industry museum is rated 4.5 out of 5 stars in 4,028 reviews. Each year, 7,600 people visit this site to admire its unique features.

When you’re done exploring for the day, you’ll drive to Venice, where you'll have a hotel waiting for you. Check in and spend some time relaxing before you head out to explore the city.

Indulge in a memorable dining experience at one of Venice's most popular restaurants, and connect with friendly locals for an authentic adventure.

Enjoy an outstanding dining experience at Local, a 1-star Michelin restaurant offering an exceptional contemporary menu. If you are in the mood for trying an alternative dining experience, consider visiting the nearby 1-star Michelin-awardee, Wistèria, known for its delicious contemporary, and venetian cuisine. Another highly-recommended restaurant in Venice is Quadri, a renowned restaurant with a 1-star Guide Michelin recognition, known for its delicious modern menu.

To truly maximize your evening out, consider visiting Al Parlamento after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to Adagio, another bar with an inviting ambiance. Similarly, Il Mercante also offers a great atmosphere, ensuring a night filled with enjoyment and relaxation.

Raise your glass to another unforgettable day in Italy!

On day 8 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Venice, and Lido. In the evening, you’ll end up in Verona, where you will stay for 1 night.

Kick off the day at Rialto Bridge, a top pick for today’s sightseeing. This stone bridge is rated an average of 4.7 out of 5 stars in 141,666 reviews.

Today is also your chance to visit Piazza San Marco. Piazza San Marco is a square with an average rating of 4.7 out of 5 stars from 152,982 reviews.

St Mark's Basilica is another top attraction we highly recommend you visit today. This cathedral is rated an average of 4.7 out of 5 stars by 18,439 visitors.

Beyond the attractions mentioned above, you also have the opportunity to visit Doge's Palace. This palace is rated an average of 4.7 out of 5 stars by 24,775 visitors. Visiting Doge's Palace means you'll be one of 318,104 people who do so every year.

Once you're ready to continue your road trip, it's time to buckle up and drive, eagerly anticipating your arrival in Lido.

An excellent attraction to start your day with is Giardini Della Biennale. This park is rated an average of 4.5 out of 5 stars in 10,729 reviews.

At the end of the day, you will drive to Verona, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As dinnertime approaches, it's time to head out for a bite to eat in Verona. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Experience a harmony of flavors at Osteria Mondo d'Oro in Verona by securing a reservation in advance. Known for its Bib Gourmand status, Osteria Mondo d'Oro offers a delightful variety of dishes highlighting its delicious italian, and seasonal menu. If you're seeking an alternative culinary experience, be sure to explore Casa Perbellini 12 Apostoli, a highly recommended restaurant known for its enticing creative, and contemporary cuisine. This popular 2-star Michelin-awarded venue consistently exceeds expectations, ensuring a memorable holiday experience. Ready for another culinary adventure? Indulge your senses at Il Desco, a highly acclaimed restaurant celebrated for its exceptional italian contemporary menu.

Continue your lively evening at Archivio, a perfect place for winding down or revving up the night, depending on which mood you’re in. La Segreteria Café is another excellent bar that offers a great selection of drinks to suit any mood. If you prefer to go somewhere else, Duchi Café ensures a night out tailored to your taste.

Take some time to reflect on your day and savor another beautiful night in Italy.

Experience an unparalleled adventure on day 9 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 2 vibrant destinations - Verona, and Ronchi. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Milan. You will spend 1 night here for some well-deserved relaxation.

Journey into the unknown at Gran Guardia, a unique attraction awaiting your visit. This remarkable palace has an average rating of 4.5 out of 5 stars from 1,551 reviews.

When you’re ready to continue your sightseeing, Verona Arena is a recommended place to visit. This opera house is rated an average of 4.7 out of 5 stars in 123,818 reviews. Based on recent data, the attraction hosts 195,540 visitors per year.

Embrace the thrill of the open road as you wave goodbye to Verona and set your GPS to Ronchi. While on the road, immerse yourself in your favorite road trip tunes or sample the sounds from a local radio station. This car ride usually takes around 35 min. Upon reaching Ronchi, unwind, observe, and explore. The best things to do, see, and eat are waiting for you.

Begin your sightseeing with a visit to Gardaland Resort. This amusement park is rated an average of 4.4 out of 5 stars in 99,291 reviews.

After soaking up all the sights of today's itinerary, you'll be ready to hit the road in the direction of your accommodation in Milan. Milan offers plenty of top-rated hotels and other places to stay on any travel budget. Take some time to relax before you head out to explore.

As you explore more of Milan, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Experience a taste of local culinary excellence while in Milan by securing a table at Enrico Bartolini al Mudec. An esteemed 3-star Michelin restaurant, it features an exceptional creative menu. For an alternative taste experience, visit Seta by Antonio Guida, famous for its scrumptious international, and contemporary dishes. This 2-star Michelin venue consistently impresses guests, making it a standout addition to your holiday plans. Looking for another choice? Discover Il Luogo Aimo e Nadia, a local favorite celebrated for its exquisite italian contemporary, and modern cuisine in Milan. Located in the heart of the city, this 1-star Michelin restaurant is an ideal pick for italian contemporary, and modern cuisine lovers seeking top-notch culinary experiences.

Following your dinner, dive into the local bar culture at Nottingham Forest. Enjoy this evening's relaxed ambiance with delightful drinks. Alternatively, go to Armani/bamboo Bar, the perfect place for those looking to experience the best of the nightlife. Similarly, Mag Cafe provides excellent drinks and a great atmosphere, ensuring a memorable night out.

As the sun sets on another day of adventure, rest up and recharge for the next leg of your road trip in Italy.

Embark on another extraordinary experience on day 10 of your road trip in Italy. Today, you will make 1 stop and experience some of the highlights of Milan. At the end of the day, you will enjoy the comforts of a top-rated hotel in Genoa, which will be your home away from home for 1 night.

When you're ready to see some sights, Duomo Di Milano Museum is a great place to start. This art museum is rated an average of 4.8 out of 5 stars by 138,554 visitors. Duomo Di Milano Museum attracts more than 341,609 visitors every year.

Another popular attraction you can visit today is Galleria Vittorio Emanuele Ii. This commercial gallery has an average rating of 4.7 out of 5 stars from 91,394 travelers.

We also recommend a stop at La Scala. The opera house has been rated an average of 4.7 out of 5 stars by 26,219 visitors.

If you're keen to explore more, consider visiting Sforzesco Castle Art Library. This library is a popular attraction with an average rating of 4.6 out of 5 stars from 68,714 reviews.

Parco Sempione is another easily accessible place to visit on this day of your trip. Stop by this park, rated 4.6 out of 5 stars in 72,914 reviews, to discover more of what makes it unique.

When you’re done exploring for the day, you’ll drive to Genoa, where you'll have a hotel waiting for you. Check in and spend some time relaxing before you head out to explore the city.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Genoa. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Get ready for an unforgettable culinary journey in Genoa by reserving a table at San Giorgio. Renowned as a 1-star Michelin restaurant, it offers an exceptional modern, and ligurian menu. For a different taste experience, head to The Cook, recognized for its delicious modern dishes. This 1-star Michelin restaurant consistently impresses guests, ensuring a memorable addition to your holiday. Looking for another option? Make sure to visit Il Marin, a local favorite known for its delightful seafood, and contemporary cuisine in Genoa. Nestled in the heart of the city, this restaurant with 1 Michelin star is an ideal choice for discerning seafood, and contemporary foodies seeking culinary excellence.

Extend your evening after a delightful meal by visiting Scurreria Beer & Bagel, which offers the perfect atmosphere for a night out. Moreover, La Lepre is another popular option for a drink or two.

Relax and reminisce about your day in Italy and look forward to more memorable moments to come!

Dive into day 11 of your remarkable road trip in Italy. Today you will explore Genoa, and Pisa, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Florence. You’ll stay here for 1 night.

Begin your sightseeing with a visit to Piazza De Ferrari. This square is rated an average of 4.6 out of 5 stars in 34,312 reviews.

Next up, make your way to Aquarium Of Genoa. This public aquarium has an average rating of 4.5 out of 5 stars from 62,259 reviews. Usually, around 1,200,000 people visit Aquarium Of Genoa every year.

After soaking in Genoa’s unique atmosphere, jump into the car with a full heart and drive in the direction of your next destination: Pisa. Expect your car journey to take a minimum of 2 hours 5 min. When you arrive in Pisa, it's time to take a break from the road.

When you're ready to see some sights, Leaning Tower Of Pisa is a great place to start. This bell tower is rated an average of 4.7 out of 5 stars by 116,882 visitors. Leaning Tower Of Pisa attracts more than 3,200,000 visitors every year.

Another popular attraction you can visit today is Piazza Del Duomo, Pisa. This square has an average rating of 4.7 out of 5 stars from 104,550 travelers.

At the end of the day, you will drive to Florence, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a day of adventure, treat yourself to an exquisite dinner at one of Florence's best restaurants.

Treat yourself to a delicious dinner at Tijuana, an excellent option for tonight's dining. Looking for something different? Djària - American Bar offers a tantalizing alternative with its diverse menu. And don’t miss Ristorante Buca Niccolini. With its reputation for pleasing customers, it’s a fantastic choice for tonight in Florence.

Head back to your accommodation in Florence and get some rest in preparation for another magical day of your road trip in Italy!

Day 12 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Florence before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

Explore local shops for souvenirs to remember your trip or find unique gifts for loved ones.

Start your sightseeing with a visit to Ponte Vecchio. This deck arch bridge is rated an average of 4.7 out of 5 stars from 118,099 visitors.

Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Florence.

Dine in style at Cibrèo Caffè, a top recommendation for dinner tonight. Or, for a change of pace, Ristorante Le Volte Firenze boasts a menu that's sure to impress.

You’ll then say farewell to Florence. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!