12-Day Italy Road Trip from Florence traveling south to Viterbo, Naples, Rome, and Siena

Welcome to Florence, the perfect starting point for your road trip in Italy! Pick up your rental car and let the adventure begin. You will spend 2 nights immersing yourself in Florence's charm before embarking on the next leg of your journey.

Florence is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Central Market or taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

As afternoon approaches, head to your chosen hotel in Florence. Check-in typically starts around 2 to 4 PM at hotels in Italy. We recommend staying at a hotel in a central location for easy access to the best attractions, restaurants, and bars in the city.

As dinnertime approaches, it's time to head out for a bite to eat in Florence. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Treat yourself to a wonderful meal at Ristorante Oliviero 1962, a top-rated dining spot in Florence. If you're in the mood for something new, try Caffe San Firenze, another premier location with a delectable menu. You might also want to book a table at Ditta Artigianale. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Florence.

After savoring a delicious meal, step into the vibrant nightlife at Manifattura, where the evening is just getting started. In the same way, Se·sto On Arno Rooftop Bar offers a unique charm perfect for experiencing the local bar scene in Florence. Archea Brewery is another top-recommended bar that is sure to get you into the mood for some dancing and celebrating.

Raise a toast to the start of your 12-day road trip in Italy!

Day 2 offers a multitude of experiences. You will stay in Florence for 1 night more, offering you enough time to explore at a relaxed pace.

Start your sightseeing with a visit to The Boboli Gardens. This park is a popular stop on travelers’ itineraries in Florence, with an average rating of 4.2 out of 5 stars by 25,341 visitors.

Pitti Palace is another popular place of interest you can visit today. The average rating of 4.6 out of 5 stars from 23,445 reviews gives you an idea of other visitors’ experience at this attraction. It’s estimated that around 198,270 people visit this art museum every year.

If it’s still bright and early, make your way to Ponte Vecchio. Visitors have rated this deck arch bridge an average of 4.7 out of 5 stars in 118,099 reviews.

Uffizi Gallery, boasting an annual visitor count of up to 2,011,219 people, is another unique site you can experience today. This attraction is a national museum rated an average of 4.7 out of 5 stars in 61,794 reviews.

Make your way to the fantastic Piazza Della Signoria, perhaps the most famous square in Florence. This attraction is rated 4.8 out of 5 stars by 66,956 travelers.

If you have an appetite for more adventure, check out the fantastic selection of tours and tickets offered in Florence on this day of your trip. You'll find the most recommended ones below.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Florence. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Discover the culinary delights of Florence by securing a reservation at Enoteca Pinchiorri. Esteemed for its 3-star Guide Michelin recognition, this restaurant offers a remarkable selection of italian contemporary cuisine. For an alternative dining experience, try Santa Elisabetta, renowned for its delicious creative, and mediterranean dishes. This esteemed 2-star Michelin-recipient consistently impresses guests, making it a must-visit spot during your holiday. Craving more culinary excitement? Head to Gucci Osteria da Massimo Bottura, a highly recommended local eatery celebrated for its mouthwatering italian contemporary, and international menu. With its 1-star Michelin recognition, it offers an unforgettable dining adventure.

Savor another day of unforgettable experiences in Italy!

Experience an unparalleled adventure on day 3 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 vibrant destinations - Florence. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Viterbo. You will spend 1 night here for some well-deserved relaxation.

Start your sightseeing with a visit to Basilica Of Santa Croce In Florence. This church is a popular stop on travelers’ itineraries in Florence, with an average rating of 4.7 out of 5 stars by 28,544 visitors.

Cathedral Of Santa Maria Del Fiore is another popular place of interest you can visit today. The average rating of 4.8 out of 5 stars from 76,359 reviews gives you an idea of other visitors’ experience at this attraction.

If it’s still bright and early, make your way to Galleria Dell'accademia. Visitors have rated this national museum an average of 4.6 out of 5 stars in 34,429 reviews. Galleria Dell'accademia receives around 1,719,645 visitors every year.

David is another unique site you can experience today. This attraction is a statue rated an average of 4.8 out of 5 stars in 10,476 reviews.

When you’re done exploring for the day, you’ll drive to Viterbo, where you'll have a hotel waiting for you. Check in and spend some time relaxing before you head out to explore the city.

Indulge in a memorable dining experience at one of Viterbo's most popular restaurants, and connect with friendly locals for an authentic adventure.

With its reputation for pleasing customers, it’s a fantastic choice for tonight in Viterbo.

Head back to your accommodation in Viterbo and get some rest in preparation for another magical day of your road trip in Italy!

Dive into day 4 of your remarkable road trip in Italy. Today you will explore Caserta, and San Leucio-complex, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Naples. You’ll stay here for 2 nights.

Caserta’s wonders await as you prepare for another journey on the road, leaving the breathtaking surroundings of Viterbo behind. This drive usually takes around 2 hours 53 min. Caserta welcomes you with a multitude of unique vacation experiences.

Begin your sightseeing with a visit to Palace Of Caserta. This extraordinary mountain park is rated an average of 4.6 out of 5 stars by 36,840 visitors. Each year, around 296,577 people visit this site to learn more about it.

Next, make your way to Giardini Reali - Parco Reggia Di Caserta. This top attraction is a point of interest with an average rating of 4.7 out of 5 stars by 18,740 visitors.

We also recommend a visit to Fountain Of Aeolus. This park is rated 4.7 out of 5 stars by 1,685 travelers.

Make English Garden one of your first sightseeing stops in San Leucio-complex. Rated an average of 4.5 out of 5 stars by 1,618 travelers, a visit to this local attraction makes for a great introduction to the area.

At the end of the day, you will drive to Naples, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you explore more of Naples, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Get ready for an unforgettable culinary journey in Naples by reserving a table at Veritas. Renowned as a 1-star Michelin restaurant, it offers an exceptional campanian, and contemporary menu. For a different taste experience, head to Il Comandante, recognized for its delicious creative, and mediterranean dishes. This 1-star Michelin restaurant consistently impresses guests, ensuring a memorable addition to your holiday. Looking for another option? Make sure to visit ARIA, a local favorite known for its delightful contemporary, and modern cuisine in Naples. Nestled in the heart of the city, this restaurant with 1 Michelin star is an ideal choice for discerning contemporary, and modern foodies seeking culinary excellence.

After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at Happening Cocktail Bar, a well-loved spot among locals and tourists. Or, head to Shanti Art Musik Bar. This bar boasts a welcoming environment that is perfect for winding down. You could also continue your night at Gran Caffè Gambrinus, another top-rated place in the area.

Raise your glass to another unforgettable day in Italy!

On day 5 of your road trip in Italy, you’ll start and end your day in Ravello, but spend the day exploring what’s beyond the village. Since you will return to Naples for 1 night more, there’s no need to rush. Experience Ravello, Amalfi, and Pompei to the fullest today with this curated day itinerary!

Ravello’s wonders await as you prepare for another journey on the road, leaving the breathtaking surroundings of Naples behind. This drive usually takes around 1 hour 10 min. Ravello welcomes you with a multitude of unique vacation experiences.

An excellent attraction to start your day with is Villa Rufolo. This sightseeing destination is rated an average of 4.6 out of 5 stars in 16,456 reviews.

When you’ve had your share of Ravello, prepare for your next destination. Admire the views and listen to some good music as you drive in the direction of Amalfi. Your travel time is around 20 min.

Make Amalfi Coast one of your first sightseeing stops in Amalfi. Rated an average of 4.7 out of 5 stars by 70,989 travelers, a visit to this local attraction makes for a great introduction to the area.

When you’ve had your share of Amalfi, prepare for your next destination. Admire the views and listen to some good music as you drive in the direction of Pompei. Your travel time is around 1 hour 1 min.

An excellent attraction to start your day with is Teatro Grande. This point of interest is rated an average of 4.7 out of 5 stars in 5,226 reviews.

Continue your journey at Archaeological Park Of Pompeii. This museum is rated 4.7 out of 5 stars by 49,465 travelers from near and far.

Pompei is also the home of Amphitheatre Of Pompeii. This sightseeing destination has an average rating of 4.7 out of 5 stars from 14,759 visitors.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Naples.

As dinnertime approaches, it's time to head out for a bite to eat in Naples. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Treat yourself to a delightful dinner at La Lazzara Trattoria e Pizzeria, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Trattoria Castel Nuovo? It's another excellent option with a diverse menu. Consider reserving a table at Ristorante Amici Miei as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Naples.

Extend your evening after a delightful meal by visiting Archivio Storico - Cocktail Bar & Wonderfood, which offers the perfect atmosphere for a night out. Moreover, Babette Pub is another popular option for a drink or two. Likewise, Gran Caffè Cimmino also provides a great ambiance for reminiscing about the day and raising a toast to your vacation.

Relax and reminisce about your day in Italy and look forward to more memorable moments to come!

Embark on another extraordinary experience on day 6 of your road trip in Italy. Today, you will make 1 stop and experience some of the highlights of Naples. At the end of the day, you will enjoy the comforts of a top-rated hotel in Rome, which will be your home away from home for 4 nights.

Make Piazza Del Plebiscito your first stop of the day. Previous visitors have rated this square an average of 4.7 out of 5 stars in 58,141 reviews.

Next up, make a stop at Castel Nuovo. With an average rating of 4.4 out of 5 stars by 28,032 visitors, it's easy to understand why so many people visit this castle every year.

Naples National Archaeological Museum is another attraction you can visit on this day of your vacation. This archaeological museum has an average rating of 4.6 out of 5 stars by 27,352 visitors. Up to 616,878 travelers come to Naples every year to see Naples National Archaeological Museum with their own eyes.

When you’re finished at Naples National Archaeological Museum, the perfect next stop is Ovo Castle. This point of interest is rated an average of 4.6 out of 5 stars in 33,595 reviews.

If you’re keen to explore even more, then consider a visit to Piazza Vincenzo Bellini. This sightseeing destination is a top place to visit, with a rating of 4.3 out of 5 stars from 3,678 reviews.

After soaking up all the sights of today's itinerary, you'll be ready to hit the road in the direction of your accommodation in Rome. Rome offers plenty of top-rated hotels and other places to stay on any travel budget. Take some time to relax before you head out to explore.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Rome. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Experience a taste of local culinary excellence while in Rome by securing a table at La Pergola. An esteemed 3-star Michelin restaurant, it features an exceptional mediterranean, and contemporary menu. For an alternative taste experience, visit Il Pagliaccio, famous for its scrumptious creative, and innovative dishes. This 2-star Michelin venue consistently impresses guests, making it a standout addition to your holiday plans. Looking for another choice? Discover Enoteca La Torre, a local favorite celebrated for its exquisite mediterranean, and creative cuisine in Rome. Located in the heart of the city, this 2-star Michelin restaurant is an ideal pick for mediterranean, and creative cuisine lovers seeking top-notch culinary experiences.

Continue the enjoyment post-dinner at La Botticella Of Poggi Giovanni, a cherished local gathering spot renowned for its welcoming atmosphere. Similarly, Sant' Eustachio Caffè offers a vibrant space for indulging in well-crafted drinks and engaging conversation. You may also want to check out Caffè Portofino. This bar is a favorite among both locals and visitors looking for a delightful evening out filled with laughter and fun.

Savor another day of unforgettable experiences in Italy!

Day 7 of your road trip across Italy promises a magnificent time exploring Rome. You have 3 nights left in Rome. Take the opportunity to experience more of the best attractions and activities in the city.

Make Castel Sant'angelo one of your first sightseeing stops in Rome. Rated an average of 4.7 out of 5 stars by 72,431 travelers, a visit to this local attraction makes for a great introduction to the area. This museum attracts 918,591 visitors every year.

Piazza Navona is a worthwhile attraction you can visit next. This square is a valued place of interest in the area, with an average rating of 4.7 out of 5 stars from 158,771 reviews.

Today is also the perfect opportunity to drop by Pantheon. This roman temple has been rated an average of 4.8 out of 5 stars by 189,682 visitors. Up to 30,000,000 people travel to this site annually.

If you’re keen to explore more, head to Piazza Del Popolo. A trip to this popular square is also your opportunity to see if it lives up to the reputable 4.6 out of 5-star rating as given by 89,807 previous visitors.

Another top place to visit is Villa Borghese. This urban zone of rome enjoys an average rating of 4.6 out of 5 stars from 69,749 local and international travelers.

To do something one-of-a-kind on this day of your trip, you can join a tour. You can discover all of the most fun and eye-opening experiences in your destination below and secure your spot here.

As dinnertime approaches, it's time to head out for a bite to eat in Rome. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Don’t miss out on dining at DEROMA - Farine Romane, a top-rated dining destination in Rome. If you're in the mood to try something new, consider La Taverna Italiana, another top spot with a mouthwatering menu. You might also want to secure a reservation at Centro. With a reputation for consistently satisfied customers, it’s a perfect choice to enhance your stay in Rome this evening.

Continue your lively evening at The Apartment Bar Roma, a perfect place for winding down or revving up the night, depending on which mood you’re in. Hotel Hassler Roma is another excellent bar that offers a great selection of drinks to suit any mood.

Say good night to Rome and look forward to another great day of your road trip in Italy!

Day 8 of your road trip will take you to the best attractions Rome has to offer. Cherish the 2 nights you have left in Rome by discovering the best things there are to see and do in the city.

A top pick for your self-guided sightseeing tour today is Circus Maximus. Previous visitors have rated this circus an average of 4.4 out of 5 stars in 44,741 reviews.

Colosseum is a local recommendation that you also can pay a visit today. This roman amphitheatre is rated an average of 4.7 out of 5 stars in 328,821 reviews. The attraction welcomes 7,400,000 visitors every year.

Another attraction you won't want to miss is Roman Forum. This square is rated an average of 4.7 out of 5 stars in 114,450 reviews.

Largo Di Torre Argentina is another outstanding experience in Rome. Around 30,433 travelers have rated this square an average of 4.5 out of 5 stars.

If you long for more, Campo De' Fiori is not far away. This square is a lovely addition to your itinerary. Previous visitors have rated it an average of 4.4 out of 5 stars in 51,133 reviews. The attraction gets an estimated 7,400,000 visitors every year.

Your discoveries in Rome do not have to stop there. Check out the fantastic selection of tours and tickets offered in Rome on this day of your trip. You can select your tours below.

As you explore more of Rome, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Enjoy a delicious meal at Ristorante Tema, a top-rated dining destination in Rome. If you're in the mood to try something new, consider Maccheroni, another top spot with a mouthwatering menu. You might also want to secure a reservation at RoYaL Art Cafè Roma. With a reputation for consistently satisfied customers, it’s a perfect choice to enhance your stay in Rome this evening.

Get a good night's sleep and look forward to another great day on the road in Italy!

On day 9 of your road trip, you will have an entire day to explore Rome. You’ll stay in Rome for 1 night and discover all the best things to see and do in the area.

Take the opportunity to see Basilica Di Santa Maria Maggiore. This attraction has an average rating of 4.8 out of 5 stars from 27,678 visitors.

Altare Della Patria is another sightseeing hotspot in the area. This architectural structure has been rated an average of 4.8 out of 5 stars by 49,843 travelers. Up to 1,683,070 people visit Altare Della Patria every year.

Rome is also the home of Trevi Fountain. Around 343,494 people have rated this sculpture an average of 4.8 out of 5 stars.

Another place you’ll want to visit is Piazza Di Spagna. With an average rating of 4.7 out of 5 stars from a total of 113,658 reviews, a visit to this square is a great idea.

This day of your vacation in Rome is also your chance to admire Spanish Steps. This must-visit monumental staircase enjoys an average rating of 4.5 out of 5 stars from 57,211 reviews.

Don’t forget to check out all the popular tours and activities you can add to your travel plan. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

After a day of adventure, treat yourself to an exquisite dinner at one of Rome's best restaurants.

Dine in style at Harry's Bar, a top recommendation for dinner tonight. Or, for a change of pace, Ristorante Amedeo boasts a menu that's sure to impress. Also, be sure to check out VinAllegro. Known as a local hotspot, it’s a great choice for tonight in Rome.

Head back to your accommodation in Rome and get some rest in preparation for another magical day of your road trip in Italy!

On day 10 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Vatican City. In the evening, you’ll end up in Siena, where you will stay for 1 night.

When you’ve had your share of Rome, prepare for your next destination. Admire the views and listen to some good music as you drive in the direction of Vatican City, Vatican City. Your travel time is around 11 min.

Be one of the day’s first visitors at St. Peter's Basilica. This major basilica is rated an average of 4.8 out of 5 stars by 131,043 visitors. Attracting more than 11,000,000 yearly visitors, it’s a top sight you don’t want to miss.

When you’re finished at St. Peter's Basilica, head to Sistine Chapel. This one-of-a-kind chapel is rated an average of 4.7 out of 5 stars in 52,083 reviews.

Beyond the above-mentioned attractions, you also have the opportunity to visit Saint Peter's Square. This square is rated an average of 4.8 out of 5 stars by 38,954 visitors.

If you’re keen to explore more, then consider a visit to Vatican Museums. This art museum is a much-appreciated attraction with an average rating of 4.6 out of 5 stars from 133,310 visitors. Around 1,612,530 travelers visit Vatican Museums every year.

When you’re done exploring for the day, you’ll drive to Siena, where you'll have a hotel waiting for you. Check in and spend some time relaxing before you head out to explore the city.

As dinnertime approaches, it's time to head out for a bite to eat in Siena. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Enjoy a lovely meal at Antica Trattoria Papei, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Osteria Quattro Venti is another top choice with a popular menu. You could also check for a table at Osteria da Divo. As an establishment that gains consistently high praises from customers, it’s an ideal choice in Siena tonight.

After your meal, keep the night alive at a bar like Meet Life Cafè, known for its lively atmosphere. Maudit Pub is another top recommendation that provides the perfect setting with well-crafted drinks and a welcoming ambiance. Similarly, Bar Impero Siena offers an excellent atmosphere for those looking to amp up the evening.

Take some time to reflect on your day and savor another beautiful night in Italy.

On day 11 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 2 destinations, Siena, and Pisa. When you’re not sightseeing, take time to relax at your selected hotel in Florence, where you’ll be staying for 1 night.

Your sightseeing of the day begins at Piazza Del Campo, a remarkable square where it’s easy to get lost in exploration. This top attraction is rated an average of 4.8 out of 5 stars in 64,175 reviews.

Next, satisfy your wanderlust at Siena Cathedral. This domus has an average rating of 4.8 out of 5 stars from 21,656 travelers.

Continue your road trip and head to your next destination, Pisa. This car ride takes around 1 hour 50 min.

Journey into the unknown at Leaning Tower Of Pisa, a unique attraction awaiting your visit. This remarkable bell tower has an average rating of 4.7 out of 5 stars from 116,882 reviews. Every year, Leaning Tower Of Pisa welcomes more than 3,200,000 curious visitors.

When you’re ready to continue your sightseeing, Piazza Del Duomo, Pisa is a recommended place to visit. This square is rated an average of 4.7 out of 5 stars in 104,550 reviews.

Another must-see attraction in Pisa is Campo Santo. Rated an average of 4.6 out of 5 stars by 586 travelers, this popular tourist destination in Pisa offers an experience you will remember.

At the end of the day, you will drive to Florence, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Florence. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Enjoy a delicious meal at Tijuana, a highly-rated dining destination in Florence. If you're eager to try something different, consider Djària - American Bar, another top spot with a tantalizing menu. You might also want to secure a reservation at Ristorante Buca Niccolini. With a reputation for consistently satisfied customers, it’s an excellent choice to enhance your stay in Florence this evening.

Relax and reminisce about your day in Italy and look forward to more memorable moments to come!

Day 12 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Florence before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

Maximize your last day in Italy and go on a shopping spree in Florence’s shopping center. Browse for souvenirs to remind you of your wonderful journey in Italy.

Make Piazzale Michelangelo one of your first sightseeing stops in Florence. Rated an average of 4.8 out of 5 stars by 77,744 travelers, a visit to this local attraction makes for a great introduction to the area.

Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Florence.

You’ll then say farewell to Florence. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!