12-Day Italy Self-Drive Road Trip With Itinerary from Genoa to La Spezia, Florence, San Gimignano, Santa Maria degli Angeli, and Rome

Day 2 of your road trip will take you to the best attractions Genoa has to offer. Cherish the 1 night you have left in Genoa by discovering the best things there are to see and do in the city.

Discover a day packed with family-friendly attractions, scenic views, and photo-friendly spots in Genoa. Begin your sightseeing with Lighthouse Of Genoa. This often recommended lighthouse is one of the top attractions in the city. Proceed to Royal Palace Museum, another must-visit attraction that enhances the city’s allure.

As you wander through the inviting streets of Genoa, soak in the lively ambiance and take the opportunity to snap some photos. Next, head to Via Garibaldi. This intriguing street is a traveler-favorite. Not far away, you’ll find Palazzo Podestà, another key site on your sightseeing itinerary. Conclude your day at Aquarium Of Genoa and uncover why it's recognized as one of the city's most widely recognized attractions.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

Experience shopping bliss at Genoa as you explore Porto Antico. Take a leisurely stroll through unique and shops, where local treasures are waiting to be found. Beyond shopping, Porto Antico offers more options, including unique attractions, key services, and vibrant events.

As you explore more of Genoa, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Enjoy a lovely dining experience at Zeffirino, a popular restaurant in Genoa. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Genoa at Trattoria Vegia Zena, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated Trattoria delle Grazie. It’s yet another ideal choice to enhance your time in Genoa tonight.

Head back to your accommodation in Genoa and get some rest in preparation for another magical day of your road trip in Italy!

Embark on another extraordinary experience on day 3 of your road trip in Italy. Today, you will make 4 stops and experience some of the highlights of Vernazza, Corniglia, Manarola, and Riomaggiore. At the end of the day, you will enjoy the comforts of a top-rated hotel in La Spezia, which will be your home away from home for 1 night.

Set out on a day brimming with fun adventures, romantic experiences, and scenic views. Start at the worthwhile Ruins Of Doria Tower, a majestic monument in Genoa. Next, go to Church Of St. Margaret Of Antioch.

After visiting Ruins Of Doria Tower and Church Of St. Margaret Of Antioch, take time to explore Genoa's streets and absorb its charm. Continue your sightseeing by heading to Cinque Terre National Park. This serene national park offers a unique experience. Manarola Overlook Viewpoint is another noteworthy stop.

At the end of the day, you will drive to La Spezia, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in La Spezia. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Treat yourself to a wonderful meal at The Colombaio Park, a top-rated dining spot in La Spezia.

As the sun sets on another day of adventure, rest up and recharge for the next leg of your road trip in Italy.

Experience an unparalleled adventure on day 4 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 vibrant destinations - Pisa. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Florence. You will spend 2 nights here for some well-deserved relaxation.

Today’s agenda in La Spezia includes a church, an art gallery, a public square, a monument and much more! Santa Maria Della Spina is must-visit church and a great starting point for the day. Next, continue your journey to Palazzo Blu, a locally appreciated art gallery, located just a leisurely stroll away. Next, head to Knights' Square, a photogenic public square, also available for your discovery today.

Each stop on today’s itinerary promises to leave you with lasting memories and a deeper appreciation for La Spezia. If you’re looking for more, Leaning Tower Of Pisa is also an iconic attraction that is worthwhile a visit. Lastly, don’t miss Piazza Del Duomo, Pisa, a timeless gem to see in the city.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Florence. Florence offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As you explore more of Florence, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Enjoy a lovely dining experience at Ristorante Oliviero 1962, a popular restaurant in Florence. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Florence at Di Poneta Novoli, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated Caffe San Firenze. It’s yet another ideal choice to enhance your time in Florence tonight.

Continue the enjoyment post-dinner at Manifattura, a cherished local gathering spot renowned for its welcoming atmosphere. Similarly, Se·sto On Arno Rooftop Bar offers a vibrant space for indulging in well-crafted drinks and engaging conversation. You may also want to check out Il Vinile. This bar is a favorite among both locals and visitors looking for a delightful evening out filled with laughter and fun.

Celebrate another amazing day of your road trip adventure in Italy!

Day 5 offers a multitude of experiences. You will stay in Florence for 1 night more, offering you enough time to explore at a relaxed pace.

Bring your curiosity for today’s adventure around Florence. Some of the city’s most loved attractions await. Cathedral Of Santa Maria Del Fiore is the perfect place to start. This church is one of the most famous places to visit in Florence. Next, head to Piazza Della Signoria, a famous public square, known for its romantic features.

In between the sights, don’t hesitate to take small detours to explore local stores and eateries. When you’re ready to continue your adventure, head to Palazzo Vecchio. This visually striking palace offers a unique experience that is highly recommended. Meanwhile, Ponte Vecchio adds its own distinct charm to your journey. Finish your day with a visit to Uffizi Gallery, a romantic art gallery in Florence.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

Indulge in a memorable dining experience at one of Florence's most popular restaurants, and connect with friendly locals for an authentic adventure.

Make sure to reserve a table at Ditta Artigianale, an iconic dining spot in Florence. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Trattoria Da Burde, a popular restaurant in Florence. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Casa Toscana, a hidden gem nestled in Florence. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at Bar 50 Rosso, a well-loved spot among locals and tourists. Or, head to Bitter Bar. This bar boasts a welcoming environment that is perfect for winding down. You could also continue your night at Archea Brewery, another top-rated place in the area.

Take some time to reflect on your day and savor another beautiful night in Italy.

On day 6 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 2 destinations, Siena and San Gimignano. When you’re not sightseeing, take time to relax at your selected hotel in San Gimignano, where you’ll be staying for 2 nights.

Today’s route brings family-friendly attractions, breathtaking views, and photo-friendly spots. The first attraction of today is Basilica Of San Domenico. This underrated church is a picture-perfect place to see in Florence. Continue your discovery at Piazza Del Campo, a romantic public square with stories to tell.

As you stroll around Florence, take in the distinct atmosphere and learn what makes this city so unique. Maximize your sightseeing with a visit to Tower Of Mangia. This beloved monument offers an awe-inspiring encounter with Florence. Next, make your way to Siena Cathedral to add another highlight to your day. After that, visit Piccolomini Library, a worthwhile library that’s sure to impress. If you’re up for more, end your self-guided sightseeing tour at Porta San Giovanni, a curiosity-inducing monument in the city. Whether you decide to get entrance tickets for all attractions or you prefer admiring from a distance, amazing experiences await on this day in Florence.

When you’re done exploring for the day, you’ll drive to your hotel in San Gimignano. Check in and spend some time relaxing before you head out to tour the village.

After a day of adventure, treat yourself to an exquisite dinner at one of San Gimignano's best restaurants.

Relax and reminisce about your day in Italy and look forward to more memorable moments to come!

On day 7 of your road trip, you will have an entire day to explore San Gimignano. You’ll stay in San Gimignano for 1 night and discover all the best things to see and do in the area.

Savor the day by visiting some of the best places to see in San Gimignano, including a public square, a museum, a park, a castle, a church and much more! Start your adventure at Piazza Del Duomo. This frequently visited public square is a must-visit for travelers looking for a unique holiday experience. Make your way to Palazzo Comunale, Pinacoteca, Torre Grossa located in San Gimignano for an enchanting atmosphere.

Next, immerse yourself in the setting of Sangimignano1300. Its history-steeped features will captivate you. After the museum, continue your tour of the village with a visit to Parco Della Rocca. This park has a romantic appeal. For a change of pace, head to Rocca Di Montestaffoli. As one of the most increasingly popular attractions in San Gimignano, this castle is an excellent place to end your self-guided tour.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in San Gimignano. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Get a good night's sleep and look forward to another great day on the road in Italy!

Dive into day 8 of your remarkable road trip in Italy. Today you will explore Santa Maria degli Angeli, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Santa Maria degli Angeli. You’ll stay here for 1 night.

Start your adventure at Basilica Of Santa Maria Degli Angeli. This well-known church is a place that is appreciated by travelers and locals alike. Next, immerse yourself in the UNESCO world heritage-listed wonders of Basilica Of San Francesco D'assisi, a must-see church in the village.

Consider stopping for a small bite to eat or a drink at a local eatery to keep your energy going. When you’re ready, continue your discovery with a visit to Porta San Giacomo. This curiosity-inducing point of interest offers an enriching experience. For a change of pace, head to Portico Of Monte Frumentario, where you can take in culturally significant features. Conclude your self-guided sightseeing tour with a visit to Rocca Maggiore and Rocca Maggiore. These sights offer a fulfilling end to a perfect day.

At the end of the day, you will drive to Santa Maria degli Angeli, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As dinnertime approaches, it's time to head out for a bite to eat in Santa Maria degli Angeli. If you are looking to dine at a popular restaurant in the town, it's often a good idea to reserve a table in advance.

Extend your evening after a delightful meal by visiting Bibenda Assisi Wine Tasting & Gourmet Food, Olive Oil And Chocolate Tastings, which offers the perfect atmosphere for a night out.

Raise your glass to another unforgettable day in Italy!

On day 9 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Rome. In the evening, you’ll end up in Rome, where you will stay for 2 nights.

Start by visiting Colosseum, a prime spot to begin your journey. This respected archeological site is sure to impress. Next on your list is Roman Forum, another must-visit landmark and wondrous archeological site renowned for its culturally significant features.

While exploring and sightseeing, take time to savor the ambiance of Santa Maria degli Angeli by sampling some local delicacies or having a drink. When you’re ready for more sightseeing, head to Pantheon. This photogenic monument is a remarkable attraction that offers a unique experience. Piazza Di Spagna also adds charm to your journey, and Piazza Del Popolo wraps up your day with its enchanting appeal.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Rome. Rome offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Rome. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Savor the flavors at La Bottega Roma, a top pick for dinner tonight. Alternatively, Pasta In Corso beckons with its unique menu offerings. Also, consider Trattoria Vecchia Roma. With its consistent customer satisfaction, it’s an excellent option for dining in Rome tonight.

Following your dinner, dive into the local bar culture at La Botticella Of Poggi Giovanni. Enjoy this evening's relaxed ambiance with delightful drinks. Alternatively, go to Almalu Trastevere, the perfect place for those looking to experience the best of the nightlife. Similarly, Bar Viminale Di Pepi Maurilio provides excellent drinks and a great atmosphere, ensuring a memorable night out.

Say good night to Rome and look forward to another great day of your road trip in Italy!

On day 10 of your road trip in Italy, you’ll start and end your day in Rome, but spend the day exploring what’s beyond the city. Since you will return to Rome for 1 night more, there’s no need to rush. Experience Vatican City and Rome to the fullest today with this curated day itinerary!

Today’s route brings family-friendly attractions, romantic experiences, and breathtaking views. The first attraction of today is Vatican Museums.

As you stroll around Rome, take in the distinct atmosphere and learn what makes this city so unique. Maximize your sightseeing with a visit to Sistine Chapel. Next, make your way to Castel Sant'angelo to add another highlight to your day. After that, visit Piazza Navona, a globally renowned public square that’s sure to impress. If you’re up for more, end your self-guided sightseeing tour at Trevi Fountain, a globally renowned monument in the city. Whether you decide to get entrance tickets for all attractions or you prefer admiring from a distance, amazing experiences await on this day in Rome.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Rome.

As you explore more of Rome, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Enjoy a delicious meal at RomAntica, a top-rated dining destination in Rome. If you're in the mood to try something new, consider Coso Ristorante, another top spot with a mouthwatering menu. You might also want to secure a reservation at DEROMA - Farine Romane. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Rome this evening.

If you’re not ready to end the night just yet, Sant' Eustachio Caffè offers a perfect venue to relax and savor a drink. Similarly, Yellowsquare Rome is well-suited for those looking to unwind in a social setting. Caffè Portofino is another excellent spot to enjoy a nightcap after a delightful meal.

Raise your glass and celebrate another amazing day of your road trip in Italy!

Embark on another extraordinary experience on day 11 of your road trip in Italy. Today, you will make 1 stop and experience some of the highlights of Orvieto. At the end of the day, you will enjoy the comforts of a top-rated hotel in Genoa, which will be your home away from home for 1 night.

Get ready for a day filled with fun adventures, scenic views, and picturesque spots in the charming village of Rome. Your adventure starts at Well Of St. Patrick, a well-known local hot spot. Another notable attraction to explore is Orvieto Cathedral. This well-known church is known for its breathtaking appeal.

After soaking in the highlights of these sights, take some time to wander Rome's streets and immerse yourself in the local atmosphere. When you're ready to continue your sightseeing adventure, head to Orvieto Underground. This photogenic cave system offers a fascinating experience that many visitors find memorable. Torre Del Moro Orvieto is also worth visiting, along with Pozzo Della Cava. These standout landmarks offer unique experiences that add to the day’s enjoyment.

When you’re done exploring for the day, you’ll drive to your hotel in Genoa. Check in and spend some time relaxing before you head out to tour the city.

Indulge in a memorable dining experience at one of Genoa's most popular restaurants, and connect with friendly locals for an authentic adventure.

Treat yourself to a delicious dinner at Osteria Sant'Ilario, an excellent option for tonight's dining. Looking for something different? La Cialtroneria offers a tantalizing alternative with its diverse menu. And don’t miss Manhattan Bar. With its reputation for pleasing customers, it’s a fantastic choice for tonight in Genoa.

Savor another day of unforgettable experiences in Italy!