12-Day Italy Self-Drive Road Trip With Itinerary from Genoa to La Spezia, Florence, San Gimignano, Santa Maria degli Angeli, and Rome

Day 2 of your road trip across Italy promises a magnificent time exploring Genoa. You have 1 night left in Genoa. Take the opportunity to experience more of the best attractions and activities in the city.

Genoa is brimming with adventures. Today’s wonderful stops include a lighthouse, a museum, a street, a palace, an aquarium, a public square and much more! Begin your sightseeing adventure at the underrated Lighthouse Of Genoa and allow yourself time to explore. Just a short distance away you'll find your next stop, Royal Palace Museum, a standout museum that draws visitors from far and near.

Continue your journey to Via Garibaldi, one of the city’s most intriguing spots that you shouldn’t miss. Another great site to visit is the often recommended Palazzo Podestà. When you're finished at the palace, Aquarium Of Genoa awaits your visit. This aquarium is a mesmerizing highlight on today's itinerary. Last up is a public square - the locally renowned Porto Antico.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

Bring home unique finds from Genoa's bustling shopping hub, Porto Antico. Enjoy a leisurely exploration of unique stores where locals shop. Don’t forget to browse souvenirs and local specialties that make perfect gifts for your loved ones. Beyond shopping, Porto Antico offers plenty of options, including primary services, unique landmarks, and community events.

Indulge in a memorable dining experience at one of Genoa's most popular restaurants, and connect with friendly locals for an authentic adventure.

Don’t miss out on dining at Zeffirino, a top-rated dining destination in Genoa. If you're in the mood to try something new, consider Trattoria Vegia Zena, another top spot with a mouthwatering menu. You might also want to secure a reservation at Trattoria delle Grazie. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Genoa this evening.

Raise your glass and celebrate another amazing day of your road trip in Italy!

Embark on another extraordinary experience on day 3 of your road trip in Italy. Today, you will make 4 stops and experience some of the highlights of Vernazza, Corniglia, Manarola, and Riomaggiore. At the end of the day, you will enjoy the comforts of a top-rated hotel in La Spezia, which will be your home away from home for 1 night.

Set out on a day brimming with fun adventures, romantic experiences, and breathtaking views. Start at the curiosity-inducing Ruins Of Doria Tower, a visually striking monument in Genoa. Next, go to Church Of St. Margaret Of Antioch.

After visiting Ruins Of Doria Tower and Church Of St. Margaret Of Antioch, have a stroll along Genoa's streets and take in the local charm. Continue your sightseeing by heading to Cinque Terre National Park. This eye-catching national park offers a unique experience. Manarola Overlook Viewpoint is another noteworthy attraction worthwhile a visit. If you still have some time left for sightseeing, we also recommend stopping by Church Of San Giovanni Battista Of Riomaggiore.

At the end of the day, you will drive to La Spezia, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As dinnertime approaches, it's time to head out for a bite to eat in La Spezia. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Treat yourself to a wonderful meal at The Colombaio Park, a top-rated dining spot in La Spezia.

Head back to your accommodation in La Spezia and get some rest in preparation for another magical day of your road trip in Italy!

On day 4 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Pisa. In the evening, you’ll end up in Florence, where you will stay for 2 nights.

Start by visiting Santa Maria Della Spina, a prime spot to begin your journey. This enchanting church is sure to impress. Next on your list is Palazzo Blu, another must-visit landmark and underrated art gallery renowned for its respected features.

While exploring and sightseeing, take time to savor the culture of La Spezia by sampling some local delicacies. When you’re ready for more sightseeing, head to Knights' Square. This historic public square is an essential place to visit for anyone looking for the full La Spezia experience. We also recommend visiting Leaning Tower Of Pisa, a globally renowned monument. Nearby, you'll also find Piazza Del Duomo, Pisa, ready to add charm to your journey. End your self-guided sightseeing tour with a stop at Pisa Cathedral and wrap up your day with its breathtaking appeal.

When you’re done exploring for the day, you’ll drive to your hotel in Florence. Check in and spend some time relaxing before you head out to tour the city.

Indulge in a memorable dining experience at one of Florence's most popular restaurants, and connect with friendly locals for an authentic adventure.

Treat yourself to a delightful dinner at Ristorante Oliviero 1962, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Di Poneta Novoli? It's another excellent option with a diverse menu. Consider reserving a table at Caffe San Firenze as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Florence.

After your meal, keep the night alive at a bar like Manifattura, known for its lively atmosphere. Se·sto On Arno Rooftop Bar is another top recommendation that provides the perfect setting with well-crafted drinks and a welcoming ambiance. Similarly, Il Vinile offers an excellent atmosphere for those looking to amp up the evening.

Say good night to Florence and look forward to another great day of your road trip in Italy!

Day 5 of your road trip will take you to the best attractions Florence has to offer. Cherish the 1 night you have left in Florence by discovering the best things there are to see and do in the city.

Today's adventure in Florence promises more breathtaking discoveries and enriching experiences! Begin at Cathedral Of Santa Maria Del Fiore. This inviting church is a highlight of any visit in the city. Then, enjoy Piazza Della Signoria, another romantic attraction that never fails to captivate visitors. Next, head over to Palazzo Vecchio, one of the city’s most well-known attractions, known for its romantic features.

If you’re looking for more, spend time soaking in the atmosphere of Ponte Vecchio. This grand historical landmark is frequented by locals and tourists alike. To complete your memorable day, make sure to visit Uffizi Gallery, a widely recognized art gallery, and take a stroll around the area. If you want to extend your self-guided sightseeing tour, go check out Basilica Of Santa Croce In Florence before you head back to your hotel.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Florence. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Treat yourself to a delicious dinner at Ditta Artigianale, an excellent option for tonight's dining. Looking for something different? Trattoria Da Burde offers a tantalizing alternative with its diverse menu. And don’t miss Casa Toscana. With its reputation for pleasing customers, it’s a fantastic choice for tonight in Florence.

Extend your evening after a delightful meal by visiting Bar 50 Rosso, which offers the perfect atmosphere for a night out. Moreover, Bitter Bar is another popular option for a drink or two. Likewise, Archea Brewery also provides a great ambiance for reminiscing about the day and raising a toast to your vacation.

Say good night to Florence and look forward to another great day of your road trip in Italy!

Dive into day 6 of your remarkable road trip in Italy. Today you will explore Siena and San Gimignano, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in San Gimignano. You’ll stay here for 2 nights.

Today, you'll explore some of the most beautiful places in Florence, including a church, a public square, a monument, a library and much more! Start your day with a visit to Basilica Of San Domenico. This locally appreciated church is a must-visit in the city. When you’re ready for your next discovery, continue to Piazza Del Campo, which may be one of the most UNESCO world heritage-listed places you will experience today.

One of the best things about exploring Florence on a self-guided tour is that you set the pace. There’s plenty of time for detours and discovering hidden gems. When you’re ready for your next stop, make your way to Tower Of Mangia, an increasingly popular monument in the city. If you’re up for more discoveries, don’t forget to reserve some time for Siena Cathedral and Piccolomini Library. End your day with a visit to Porta San Giovanni, an intriguing monument that’s sure to leave a lasting impression.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in San Gimignano. San Gimignano offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As you explore more of San Gimignano, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Relax and recharge in preparation for another adventurous day in Italy!

On day 7 of your road trip, you will have an entire day to explore San Gimignano. You’ll stay in San Gimignano for 1 night and discover all the best things to see and do in the area.

Savor the day by visiting some of the best places to see in San Gimignano, including a public square, a museum, a park, a castle, a church and much more! Start your adventure at Piazza Del Duomo. This increasingly popular public square is a must-visit for travelers looking for a unique holiday experience. Make your way to Palazzo Comunale, Pinacoteca, Torre Grossa located in San Gimignano for another exciting encounter.

Next, immerse yourself in the setting of Sangimignano1300. Its respected features will captivate you. After the museum, continue your tour of the village with a visit to Parco Della Rocca. Visitors usually appreciate the history-steeped features of this park. Next up is Rocca Di Montestaffoli, a highly recommended castle. For a change of pace, head to Chiesa Di Sant'agostino. As one of the most locally appreciated attractions in San Gimignano, this church is the perfect place to end your self-guided sightseeing tour.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in San Gimignano. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Relax and recharge in preparation for another adventurous day in Italy!

Experience an unparalleled adventure on day 8 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 vibrant destinations - Santa Maria degli Angeli. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Santa Maria degli Angeli. You will spend 1 night here for some well-deserved relaxation.

Basilica Of Santa Maria Degli Angeli is must-visit church and a great starting point for the day. Next, continue your journey to Basilica Of San Francesco D'assisi, a notable church, located just a leisurely stroll away.

Each stop on today’s itinerary promises to leave you with lasting memories and a deeper appreciation for San Gimignano. When you're ready, let your sightseeing route take you to the increasingly popular Portico Of Monte Frumentario. If you’re looking for more, Rocca Maggiore is also a beloved attraction that is worthwhile a visit. Lastly, don’t miss Piazza Del Comune, a place of enchanting interest in the village.

At the end of the day, you will drive to Santa Maria degli Angeli, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Santa Maria degli Angeli. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at Bibenda Assisi Wine Tasting & Gourmet Food, Olive Oil And Chocolate Tastings, a well-loved spot among locals and tourists.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in Italy.

On day 9 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, Rome. When you’re not sightseeing, take time to relax at your selected hotel in Rome, where you’ll be staying for 2 nights.

Today's adventure in Santa Maria degli Angeli promises more breathtaking discoveries and enriching experiences! Begin at Colosseum. This respected archeological site is a highlight of any visit in the city. Then, enjoy Roman Forum, another respected attraction that never fails to captivate visitors. Next, head over to Pantheon, one of the city’s most world-famous attractions, known for its photogenic features.

If you’re looking for more, spend time soaking in the atmosphere of Piazza Di Spagna. This majestic public square is frequented by locals and tourists alike. To complete your memorable day, make sure to visit Piazza Del Popolo, an astonishing public square, and take a stroll around the area.

When you’re done exploring for the day, you’ll drive to your hotel in Rome. Check in and spend some time relaxing before you head out to tour the city.

After a day of adventure, treat yourself to an exquisite dinner at one of Rome's best restaurants.

Make sure to reserve a table at La Bottega Roma, an iconic dining spot in Rome. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Pasta In Corso, a popular restaurant in Rome. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Trattoria Vecchia Roma, a hidden gem nestled in Rome. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Keep the evening going at La Botticella Of Poggi Giovanni, a great choice for enjoying the after-dinner hours with a drink. You could also go to Almalu Trastevere, which offers a similarly pleasant setting and great drinks. Another option is Bar Viminale Di Pepi Maurilio, which provides an inviting environment for unwinding after a busy day out.

Raise your glass to another unforgettable day in Italy!

Greet day 10 of your road trip in Italy with a smile and start your day with a hearty breakfast. You will return to Rome for your remaining 1 night in the city later today, but first, it’s time for some exploring! On the agenda for this day, you’ll find only the best things to see and do in Vatican City and Rome.

Enjoy the perfect balance of relaxation and exploration in Rome today. One of the most world-famous attractions included on the itinerary is Vatican Museums.

Throughout the day, make sure to take breaks to appreciate the surroundings. Next up, visit the famous Sistine Chapel. After exploring the chapel, head to Castel Sant'angelo. This impressive castle is a highlight in Rome. As your day continues, stop by Piazza Navona, known for its culturally significant features. Lastly, don’t forget to check out the iconic Trevi Fountain. Enjoy exploring this incredible monument at your own pace.

When you’re done exploring for the day, you’ll return to Rome and your accommodation.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Rome. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Make sure to reserve a table at RomAntica, an iconic dining spot in Rome. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Coso Ristorante, a popular restaurant in Rome. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of DEROMA - Farine Romane, a hidden gem nestled in Rome. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Continue your evening by exploring the vibrant nightlife scene at Sant' Eustachio Caffè, a prime destination for a thrilling night out. Also, don’t forget to check out Yellowsquare Rome, a bar that offers unique local touches. Likewise, Caffè Portofino provides an excellent alternative for a fun evening.

Relax and reminisce about your day in Italy and look forward to more memorable moments to come!

Embark on another extraordinary experience on day 11 of your road trip in Italy. Today, you will make 1 stop and experience some of the highlights of Orvieto. At the end of the day, you will enjoy the comforts of a top-rated hotel in Genoa, which will be your home away from home for 1 night.

Get ready for an exciting day in Rome. Today’s sightseeing agenda includes a monument, a church, a cave system, a cave and much more! Begin your adventure at Well Of St. Patrick. This is an interesting monument you should not miss. Another must-see is Orvieto Cathedral, a well-known church in Rome.

When you’re ready for the next sight, head to Orvieto Underground. From there, take a leisurely stroll to Torre Del Moro Orvieto, another of the village’s often recommended attractions. We recommend continuing your self-guided tour at Pozzo Della Cava, a standout place of interest in the village.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Genoa. Genoa offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Genoa. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Enjoy a lovely dining experience at Osteria Sant'Ilario, a popular restaurant in Genoa. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Genoa at La Cialtroneria, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated Manhattan Bar. It’s yet another ideal choice to enhance your time in Genoa tonight.

Get a good night's sleep and look forward to another great day on the road in Italy!