12-Day Italy Self-Drive Road Trip With Itinerary from Genoa to La Spezia, Florence, San Gimignano, Santa Maria degli Angeli, and Rome

On day 2 of your road trip, you will have an entire day to explore Genoa. You’ll stay in Genoa for 1 night and discover all the best things to see and do in the area.

Bring your curiosity for today’s adventure around Genoa. Some of the city’s most loved attractions await! Lighthouse Of Genoa is the perfect place to start. This lighthouse is one of the most often recommended places to visit in Genoa. Next, head to Royal Palace Museum, a beloved museum, known for its historic features.

In between the sights, don’t hesitate to take small detours to explore local stores and eateries. When you’re ready to continue your adventure, head to Via Garibaldi. This history-steeped street is a highly recommended experience. Nearby, you'll also find Palazzo Podestà and Aquarium Of Genoa. Visit these for an interesting touch to your journey. Finish the day with a visit to Porto Antico, a visually striking public square in Genoa.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

Experience shopping bliss at Genoa as you explore Via Garibaldi. Take a leisurely stroll through unique and shops, where local treasures are waiting to be found. Beyond shopping, Via Garibaldi offers more options, including unique attractions, key services, and vibrant events.

As dinnertime approaches, it's time to head out for a bite to eat in Genoa. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Enjoy a delicious meal at Zeffirino, a highly-rated dining destination in Genoa. If you're eager to try something different, consider Trattoria Vegia Zena, another top spot with a tantalizing menu. You might also want to secure a reservation at Trattoria delle Grazie. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Genoa this evening.

Raise your glass to another unforgettable day in Italy!

Experience an unparalleled adventure on day 3 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 4 vibrant destinations - Vernazza, Corniglia, Manarola, and Riomaggiore. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in La Spezia. You will spend 1 night here for some well-deserved relaxation.

Enjoy the perfect balance of relaxation and exploration in Genoa today. One of the most intriguing attractions included on the itinerary is Ruins Of Doria Tower. This romantic monument will help you start your sightseeing on top. Then, take a leisurely stroll to Church Of St. Margaret Of Antioch and learn what makes this picture-perfect church unique.

Throughout the day, make sure to take breaks to appreciate the surroundings. Next up, visit the notable Cinque Terre National Park. After exploring the national park, head to Manarola Overlook Viewpoint. This often recommended observation deck is a highlight in Genoa. Lastly, don’t forget to check out the locally appreciated Church Of San Giovanni Battista Of Riomaggiore. Enjoy exploring this incredible church at your own pace.

When you’re done exploring for the day, you’ll drive to your hotel in La Spezia. Check in and spend some time relaxing before you head out to tour the city.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in La Spezia. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Savor the flavors at The Colombaio Park, a top pick for dinner tonight.

Relax and reminisce about your day in Italy and look forward to more memorable moments to come!

On day 4 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, Pisa. When you’re not sightseeing, take time to relax at your selected hotel in Florence, where you’ll be staying for 2 nights.

Today's adventure in La Spezia promises more breathtaking discoveries and enriching experiences! Begin at Santa Maria Della Spina. This inviting church is a highlight of any visit in the city. Then, enjoy Palazzo Blu, another heritage-rich attraction that never fails to captivate visitors. Next, head over to Knights' Square, one of the city’s most underrated attractions, known for its awe-inspiring features.

If you’re looking for more, spend time soaking in the atmosphere of Leaning Tower Of Pisa. This historic monument is frequented by locals and tourists alike. To complete your memorable day, make sure to visit Piazza Del Duomo, Pisa, an iconic public square, and take a stroll around the area. If you want to extend your self-guided sightseeing tour, go check out Pisa Cathedral before you head back to your hotel.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Florence. Florence offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

Indulge in a memorable dining experience at one of Florence's most popular restaurants, and connect with friendly locals for an authentic adventure.

Treat yourself to a wonderful meal at Ristorante Oliviero 1962, a top-rated dining spot in Florence. If you're in the mood for something new, try Di Poneta Novoli, another premier location with a delectable menu. You might also want to book a table at Caffe San Firenze. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Florence.

If you’re not ready to end the night just yet, Manifattura offers a perfect venue to relax and savor a drink. Similarly, Se·sto On Arno Rooftop Bar is well-suited for those looking to unwind in a social setting. Il Vinile is another excellent spot to enjoy a nightcap after a delightful meal.

Take some time to reflect on your day and savor another beautiful night in Italy.

Day 5 of your road trip across Italy promises a magnificent time exploring Florence. You have 1 night left in Florence. Take the opportunity to experience more of the best attractions and activities in the city.

Set out on a day brimming with fun adventures, romantic experiences, and breathtaking views. Start at the extraordinary Cathedral Of Santa Maria Del Fiore, a visually striking church in Florence. Next, go to Piazza Della Signoria.

After visiting Cathedral Of Santa Maria Del Fiore and Piazza Della Signoria, have a stroll along Florence's streets and take in the local charm. Continue your sightseeing by heading to Palazzo Vecchio. This enchanting palace offers a unique experience. Ponte Vecchio is another noteworthy attraction worthwhile a visit. End your self-guided sightseeing tour on top with a visit to Uffizi Gallery, one of the most romantic places to visit in Florence. If you still have some time left for sightseeing, we also recommend stopping by Basilica Of Santa Croce In Florence.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Florence. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Have a fantastic dining experience at Ditta Artigianale, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Trattoria Da Burde offers an enticing alternative with its varied menu. Additionally, Casa Toscana is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Florence.

Continue the enjoyment post-dinner at Bar 50 Rosso, a cherished local gathering spot renowned for its welcoming atmosphere. Similarly, Bitter Bar offers a vibrant space for indulging in well-crafted drinks and engaging conversation. You may also want to check out Archea Brewery. This bar is a favorite among both locals and visitors looking for a delightful evening out filled with laughter and fun.

Raise your glass and celebrate another amazing day of your road trip in Italy!

On day 6 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Siena and San Gimignano. In the evening, you’ll end up in San Gimignano, where you will stay for 2 nights.

Savor the day by visiting some of the best places to see in Florence, including a church, a public square, a monument, a library and much more! Start your adventure at Basilica Of San Domenico. This intriguing church is a must-visit for travelers looking for a unique holiday experience. Make your way to Piazza Del Campo located in Florence for another exciting encounter.

Next, immerse yourself in the setting of Tower Of Mangia. Its culturally significant features will captivate you. After the monument, continue your tour of the city with a visit to Siena Cathedral. Visitors usually appreciate the enchanting features of this church. Next up is Piccolomini Library, a highly recommended library. For a change of pace, head to Porta San Giovanni. As one of the most frequently visited attractions in Florence, this monument is the perfect place to end your self-guided sightseeing tour.

At the end of the day, you will drive to San Gimignano, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in San Gimignano. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in Italy.

Day 7 offers a multitude of experiences. You will stay in San Gimignano for 1 night more, offering you enough time to explore at a relaxed pace.

Today’s well-planned self-sightseeing route offers several family-friendly attractions, romantic experiences, and scenic views. Whether you decide to explore San Gimignano on foot, use public transport, or join a guided tour, there are a few attractions you don’t want to miss. Piazza Del Duomo is the first of them. Spend some time admiring this inviting public square before continuing your journey. Palazzo Comunale, Pinacoteca, Torre Grossa is your next stop. This underrated museum is one of the best-rated sights in San Gimignano.

Consider grabbing some lunch or a light snack to keep your energy going. Beyond the above-mentioned attractions, today is also the perfect time to visit Sangimignano1300. This respected museum is a sight to behold. To round off your sightseeing experience, visit Parco Della Rocca and Rocca Di Montestaffoli. If time allows, end your day with Chiesa Di Sant'agostino, a photogenic church that offers a memorable conclusion to your exploration.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

As you explore more of San Gimignano, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Relax and recharge in preparation for another adventurous day in Italy!

Embark on another extraordinary experience on day 8 of your road trip in Italy. Today, you will make 1 stop and experience some of the highlights of Santa Maria degli Angeli. At the end of the day, you will enjoy the comforts of a top-rated hotel in Santa Maria degli Angeli, which will be your home away from home for 1 night.

Discover a day packed with fun adventures, breathtaking views, and picturesque spots in San Gimignano. Begin your sightseeing with Basilica Of Santa Maria Degli Angeli. This popular church is one of the top attractions in the village. Proceed to Basilica Of San Francesco D'assisi, another must-visit attraction.

As you wander through the inviting streets of San Gimignano, soak in the lively ambiance and take the opportunity to snap some photos. Next, head to Porta San Giacomo. This curiosity-inducing point of interest is a traveler-favorite. Not far away, you’ll find Portico Of Monte Frumentario, another key site on your sightseeing itinerary. Rocca Maggiore is yet another highly recommended place to visit nearby, offering plenty to discover for curious travelers. Conclude your day at Piazza Del Comune and uncover why it's recognized as one of the village's most curiosity-inducing attractions.

When you’re done exploring for the day, you’ll drive to your hotel in Santa Maria degli Angeli. Check in and spend some time relaxing before you head out to tour the town.

After a day of adventure, treat yourself to an exquisite dinner at one of Santa Maria degli Angeli's best restaurants.

To truly maximize your evening out, consider visiting Bibenda Assisi Wine Tasting & Gourmet Food, Olive Oil And Chocolate Tastings after dinner. This bar is known for offering some of the best drinks and vibes in the city.

Celebrate another amazing day of your road trip adventure in Italy!

Dive into day 9 of your remarkable road trip in Italy. Today you will explore Rome, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Rome. You’ll stay here for 2 nights.

Set out on a day brimming with family-friendly attractions, breathtaking views, and picturesque spots. Start at the world-famous Colosseum, an awe-inspiring archeological site in Santa Maria degli Angeli. Next, go to Roman Forum.

After visiting Colosseum and Roman Forum, have a stroll along Santa Maria degli Angeli's streets and take in the local charm. Continue your sightseeing by heading to Pantheon. This culturally significant monument offers a unique experience. Piazza Di Spagna is another noteworthy attraction worthwhile a visit. End your self-guided sightseeing tour on top with a visit to Piazza Del Popolo, one of the most enchanting places to visit in Santa Maria degli Angeli.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Rome. Rome offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As dinnertime approaches, it's time to head out for a bite to eat in Rome. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Enjoy a delicious meal at La Bottega Roma, a highly-rated dining destination in Rome. If you're eager to try something different, consider Pasta In Corso, another top spot with a tantalizing menu. You might also want to secure a reservation at Trattoria Vecchia Roma. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Rome this evening.

After enjoying a fulfilling meal, continue your evening at La Botticella Of Poggi Giovanni, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, Almalu Trastevere offers a welcoming atmosphere for easing into the nightlife. Similarly, Bar Viminale Di Pepi Maurilio provides an excellent environment for a relaxed and enjoyable evening.

Head back to your accommodation in Rome and get some rest in preparation for another magical day of your road trip in Italy!

Greet day 10 of your road trip in Italy with a smile and start your day with a hearty breakfast. You will return to Rome for your remaining 1 night in the city later today, but first, it’s time for some exploring! On the agenda for this day, you’ll find only the best things to see and do in Vatican City and Rome.

Set out on a day brimming with fun adventures, romantic experiences, and scenic views. Next, go to St. Peter's Basilica.

Castel Sant'angelo is another noteworthy attraction worthwhile a visit. End your self-guided sightseeing tour on top with a visit to Piazza Navona, one of the most visually striking places to visit in Rome. If you still have some time left for sightseeing, we also recommend stopping by Trevi Fountain.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Rome.

Indulge in a memorable dining experience at one of Rome's most popular restaurants, and connect with friendly locals for an authentic adventure.

Treat yourself to a delightful dinner at RomAntica, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Coso Ristorante? It's another excellent option with a diverse menu. Consider reserving a table at DEROMA - Farine Romane as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Rome.

Explore the vibrant nightlife at Sant' Eustachio Caffè after your meal, a hub for lively evenings and memorable moments. Or, head to Yellowsquare Rome for a great selection of flavorful drinks and a charming setting. Furthermore, Caffè Portofino is perfect for those looking to extend their night with a touch of local flavor.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in Italy.

Experience an unparalleled adventure on day 11 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 vibrant destinations - Orvieto. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Genoa. You will spend 1 night here for some well-deserved relaxation.

Start by visiting Well Of St. Patrick, a prime spot to begin your journey. This culturally significant monument is sure to impress. Next on your list is Orvieto Cathedral, another must-visit landmark and well-known church renowned for its romantic features.

While exploring and sightseeing, take time to savor the culture of Rome by sampling some local delicacies. When you’re ready for more sightseeing, head to Orvieto Underground. This photogenic cave system is an essential place to visit for anyone looking for the full Rome experience. We also recommend visiting Torre Del Moro Orvieto, a beloved monument. Nearby, you'll also find Pozzo Della Cava, ready to add charm to your journey.

At the end of the day, you will drive to Genoa, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you explore more of Genoa, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Treat yourself to a delicious dinner at Osteria Sant'Ilario, an excellent option for tonight's dining. Looking for something different? La Cialtroneria offers a tantalizing alternative with its diverse menu. And don’t miss Manhattan Bar. With its reputation for pleasing customers, it’s a fantastic choice for tonight in Genoa.

Get a good night's sleep and look forward to another great day on the road in Italy!