12-Day Italy Self-Drive Road Trip With Itinerary from Genoa to La Spezia, Florence, San Gimignano, Santa Maria degli Angeli, and Rome

Day 2 of your road trip will take you to the best attractions Genoa has to offer. Cherish the 1 night you have left in Genoa by discovering the best things there are to see and do in the city.

Genoa is home to plenty of attractions that offer fun adventures, scenic views, and photo-friendly spots! Start at Lighthouse Of Genoa, an up-and-coming lighthouse that is worthwhile a visit in the city. Nearby, you’ll find Royal Palace Museum, enchanting visitors with its breathtaking appeal. Continue your exploration at Via Garibaldi. This street is one of the city’s most often recommended spots.

Enjoy the freedom of exploring Genoa at your own pace and find hidden gems along the way. If you want to see more picture-perfect spots, make sure to visit Palazzo Podestà. After exploring the palace, head to the top-rated Aquarium Of Genoa. Lastly, wrap up today’s self-guided sightseeing tour with a visit to Porto Antico, a place of romantic interest in Genoa.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

Visit Via Garibaldi in Genoa for an unforgettable shopping experience. Browse unique and stores, each offering delightful surprises. Find unique souvenirs or items to take home. After shopping, explore what Via Garibaldi has to offer, including attractions, essential services, and vibrant community activities.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Genoa. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Don’t miss out on dining at Zeffirino, a top-rated dining destination in Genoa. If you're in the mood to try something new, consider Trattoria Vegia Zena, another top spot with a mouthwatering menu. You might also want to secure a reservation at Trattoria delle Grazie. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Genoa this evening.

Relax and reminisce about your day in Italy and look forward to more memorable moments to come!

On day 3 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 4 destinations, Vernazza, Corniglia, Manarola, and Riomaggiore. When you’re not sightseeing, take time to relax at your selected hotel in La Spezia, where you’ll be staying for 1 night.

Start your adventure at Ruins Of Doria Tower. This worthwhile monument is a place that is appreciated by travelers and locals alike. Next, immerse yourself in the instagrammable wonders of Church Of St. Margaret Of Antioch, a must-see church in the village.

Consider stopping for a small bite to eat or a drink at a local eatery to keep your energy going. When you’re ready, continue your discovery with a visit to Cinque Terre National Park. This popular national park offers an enriching experience. For a change of pace, head to Manarola Overlook Viewpoint, where you can take in mesmerizing features. Conclude your self-guided sightseeing tour with a visit to Riomaggiore and Church Of San Giovanni Battista Of Riomaggiore. These sights offer a fulfilling end to a perfect day.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in La Spezia. La Spezia offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a day of adventure, treat yourself to an exquisite dinner at one of La Spezia's best restaurants.

Treat yourself to a wonderful meal at The Colombaio Park, a top-rated dining spot in La Spezia.

Say good night to La Spezia and look forward to another great day of your road trip in Italy!

Embark on another extraordinary experience on day 4 of your road trip in Italy. Today, you will make 1 stop and experience some of the highlights of Pisa. At the end of the day, you will enjoy the comforts of a top-rated hotel in Florence, which will be your home away from home for 2 nights.

Bring your curiosity for today’s adventure around La Spezia. Some of the city’s most loved attractions await! Santa Maria Della Spina is the perfect place to start. This church is one of the most curiosity-inducing places to visit in La Spezia. Next, head to Palazzo Blu, an often recommended art gallery, known for its historic features.

In between the sights, don’t hesitate to take small detours to explore local stores and eateries. When you’re ready to continue your adventure, head to Knights' Square. This historic public square is a highly recommended experience. Nearby, you'll also find Leaning Tower Of Pisa and Piazza Del Duomo, Pisa. Visit these for an interesting touch to your journey. Finish the day with a visit to Pisa Cathedral, an UNESCO world heritage-listed church in La Spezia.

At the end of the day, you will drive to Florence, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Florence. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Don’t miss out on dining at Ristorante Oliviero 1962, a top-rated dining destination in Florence. If you're in the mood to try something new, consider Di Poneta Novoli, another top spot with a mouthwatering menu. You might also want to secure a reservation at Caffe San Firenze. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Florence this evening.

Round off your dining experience by visiting Manifattura, a prime location for a drink. Alternatively, explore the distinctive characteristics of Se·sto On Arno Rooftop Bar, a bar catering to every mood and preference. Il Vinile likewise offers a unique atmosphere, perfect for a memorable night out.

Take some time to reflect on your day and savor another beautiful night in Italy.

Day 5 offers a multitude of experiences. You will stay in Florence for 1 night more, offering you enough time to explore at a relaxed pace.

Today’s itinerary in Florence covers several incredible sights, including a church, a public square, a palace, a historical landmark, an art gallery and much more! Start your adventure at Cathedral Of Santa Maria Del Fiore. This astonishing church is a place that is appreciated by travelers and locals alike. Next, immerse yourself in the noteworthy wonders of Piazza Della Signoria, a must-see public square in the city.

Consider stopping for a small bite to eat or a drink at a local eatery to keep your energy going. When you’re ready, continue your discovery with a visit to Palazzo Vecchio. This captivating palace offers an enriching experience. For a change of pace, head to Ponte Vecchio, where you can take in history-steeped features. Conclude your self-guided sightseeing tour with a visit to Uffizi Gallery and Basilica Of Santa Croce In Florence. These sights offer a fulfilling end to a perfect day.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

As you explore more of Florence, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Savor the flavors at Ditta Artigianale, a top pick for dinner tonight. Alternatively, Trattoria Da Burde beckons with its unique menu offerings. Also, consider Casa Toscana. With its consistent customer satisfaction, it’s an excellent option for dining in Florence tonight.

Continue your evening by exploring the vibrant nightlife scene at Bar 50 Rosso, a prime destination for a thrilling night out. Also, don’t forget to check out Bitter Bar, a bar that offers unique local touches. Likewise, Archea Brewery provides an excellent alternative for a fun evening.

As the sun sets on another day of adventure, rest up and recharge for the next leg of your road trip in Italy.

Experience an unparalleled adventure on day 6 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 2 vibrant destinations - Siena and San Gimignano. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in San Gimignano. You will spend 2 nights here for some well-deserved relaxation.

Today’s agenda in Florence includes a church, a public square, a monument, a library and much more! Basilica Of San Domenico is must-visit church and a great starting point for the day. Next, continue your journey to Piazza Del Campo, a widely recognized public square, located just a leisurely stroll away. Next, head to Tower Of Mangia, a culturally significant monument, also available for your discovery today.

Each stop on today’s itinerary promises to leave you with lasting memories and a deeper appreciation for Florence. When you're ready, let your sightseeing route take you to the captivating Siena Cathedral. If you’re looking for more, Piccolomini Library is also an up-and-coming attraction that is worthwhile a visit. Lastly, don’t miss Porta San Giovanni, a place of respected interest in the city.

When you’re done exploring for the day, you’ll drive to your hotel in San Gimignano. Check in and spend some time relaxing before you head out to tour the village.

Indulge in a memorable dining experience at one of San Gimignano's most popular restaurants, and connect with friendly locals for an authentic adventure.

Get a good night's sleep and look forward to another great day on the road in Italy!

Day 7 of your road trip across Italy promises a magnificent time exploring San Gimignano. You have 1 night left in San Gimignano. Take the opportunity to experience more of the best attractions and activities in the village.

Today’s agenda in San Gimignano includes a public square, a museum, a park, a castle, a church and much more! Piazza Del Duomo is must-visit public square and a great starting point for the day. Next, continue your journey to Palazzo Comunale, Pinacoteca, Torre Grossa, a locally appreciated museum, located just a leisurely stroll away. Next, head to Sangimignano1300, a historic museum, also available for your discovery today.

Each stop on today’s itinerary promises to leave you with lasting memories and a deeper appreciation for San Gimignano. When you're ready, let your sightseeing route take you to the underrated Parco Della Rocca. If you’re looking for more, Rocca Di Montestaffoli is also a beloved attraction that is worthwhile a visit. Lastly, don’t miss Chiesa Di Sant'agostino, a place of respected interest in the village.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

As dinnertime approaches, it's time to head out for a bite to eat in San Gimignano. If you are looking to dine at a popular restaurant in the village, it's often a good idea to reserve a table in advance.

Celebrate another amazing day of your road trip adventure in Italy!

On day 8 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Santa Maria degli Angeli. In the evening, you’ll end up in Santa Maria degli Angeli, where you will stay for 1 night.

Set out on a day brimming with fun adventures, breathtaking views, and photo-friendly spots. Start at the interesting Basilica Of Santa Maria Degli Angeli, an UNESCO world heritage-designated church in San Gimignano. Next, go to Basilica Of San Francesco D'assisi.

Portico Of Monte Frumentario is another noteworthy attraction worthwhile a visit. End your self-guided sightseeing tour on top with a visit to Rocca Maggiore, one of the most visually striking places to visit in San Gimignano. If you still have some time left for sightseeing, we also recommend stopping by Piazza Del Comune.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Santa Maria degli Angeli. Santa Maria degli Angeli offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As you explore more of Santa Maria degli Angeli, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Cap off your dinner by heading to Bibenda Assisi Wine Tasting & Gourmet Food, Olive Oil And Chocolate Tastings, ideal for a leisurely evening with a drink in hand.

Raise your glass and celebrate another amazing day of your road trip in Italy!

Dive into day 9 of your remarkable road trip in Italy. Today you will explore Rome, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Rome. You’ll stay here for 2 nights.

Today’s route brings family-friendly attractions, breathtaking views, and photo-friendly spots. The first attraction of today is Colosseum. This globally renowned archeological site is a picture-perfect place to see in Santa Maria degli Angeli. Continue your discovery at Roman Forum, an UNESCO world heritage-listed archeological site with stories to tell.

As you stroll around Santa Maria degli Angeli, take in the distinct atmosphere and learn what makes this city so unique. Maximize your sightseeing with a visit to Pantheon. This globally renowned monument offers a heritage-rich encounter with Santa Maria degli Angeli. Next, make your way to Piazza Di Spagna to add another highlight to your day. After that, visit Piazza Del Popolo, an extraordinary public square that’s sure to impress. Whether you decide to get entrance tickets for all attractions or you prefer admiring from a distance, amazing experiences await on this day in Santa Maria degli Angeli.

At the end of the day, you will drive to Rome, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As dinnertime approaches, it's time to head out for a bite to eat in Rome. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Enjoy a delicious meal at La Bottega Roma, a highly-rated dining destination in Rome. If you're eager to try something different, consider Pasta In Corso, another top spot with a tantalizing menu. You might also want to secure a reservation at Trattoria Vecchia Roma. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Rome this evening.

Continue the enjoyment post-dinner at La Botticella Of Poggi Giovanni, a cherished local gathering spot renowned for its welcoming atmosphere. Similarly, Almalu Trastevere offers a vibrant space for indulging in well-crafted drinks and engaging conversation. You may also want to check out Bar Viminale Di Pepi Maurilio. This bar is a favorite among both locals and visitors looking for a delightful evening out filled with laughter and fun.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in Italy.

Wake up to day 10 of your extraordinary road trip in Italy. With 1 night left in Rome, we encourage you to seize the day and discover the unexplored beauty of the city’s surroundings!

Enjoy the perfect balance of relaxation and exploration in Rome today. One of the most wondrous attractions included on the itinerary is Vatican Museums.

Throughout the day, make sure to take breaks to appreciate the surroundings. Next up, visit the famous Sistine Chapel. After exploring the chapel, head to Castel Sant'angelo. This impressive castle is a highlight in Rome. As your day continues, stop by Piazza Navona, known for its romantic features. Lastly, don’t forget to check out the wondrous Trevi Fountain. Enjoy exploring this incredible monument at your own pace.

When you’re done exploring for the day, you’ll return to Rome and your accommodation.

Indulge in a memorable dining experience at one of Rome's most popular restaurants, and connect with friendly locals for an authentic adventure.

Savor the flavors at RomAntica, a top pick for dinner tonight. Alternatively, Coso Ristorante beckons with its unique menu offerings. Also, consider DEROMA - Farine Romane. With its consistent customer satisfaction, it’s an excellent option for dining in Rome tonight.

After your meal, keep the night alive at a bar like Sant' Eustachio Caffè, known for its lively atmosphere. Yellowsquare Rome is another top recommendation that provides the perfect setting with well-crafted drinks and a welcoming ambiance. Similarly, Caffè Portofino offers an excellent atmosphere for those looking to amp up the evening.

Head back to your accommodation in Rome and get some rest in preparation for another magical day of your road trip in Italy!

On day 11 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, Orvieto. When you’re not sightseeing, take time to relax at your selected hotel in Genoa, where you’ll be staying for 1 night.

Today, you'll explore some of the most beautiful places in Rome, including a monument, a church, a cave system, a cave and much more! Start your day with a visit to Well Of St. Patrick. This notable monument is a must-visit in the village. When you’re ready for your next discovery, continue to Orvieto Cathedral, which may be one of the most inviting places you will experience today.

One of the best things about exploring Rome on a self-guided tour is that you set the pace. There’s plenty of time for detours and discovering hidden gems. When you’re ready for your next stop, make your way to Orvieto Underground, a worthwhile cave system in the village. If you’re up for more discoveries, don’t forget to reserve some time for Torre Del Moro Orvieto and Pozzo Della Cava.

When you’re done exploring for the day, you’ll drive to your hotel in Genoa. Check in and spend some time relaxing before you head out to tour the city.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Genoa. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Savor the flavors at Osteria Sant'Ilario, a top pick for dinner tonight. Alternatively, La Cialtroneria beckons with its unique menu offerings. Also, consider Manhattan Bar. With its consistent customer satisfaction, it’s an excellent option for dining in Genoa tonight.

Raise your glass to another unforgettable day in Italy!