12-Day Italy Self-Drive Road Trip With Itinerary from Genoa traveling east to Corniglia, Florence, and Rome

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Escape the ordinary with this exciting 12-day road trip through Italy. Explore the diverse landscapes, lively cities, and beyond. Pack your bags, hit the road, and prepare for an unforgettable journey!

This perfectly planned road trip itinerary in Italy takes you through some of the best places to see in the country. You will spend 3 nights in Genoa, 2 nights in Corniglia, 3 nights in Florence, and 3 nights in Rome. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Genoa, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Trevi Fountain and Colosseum are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Pantheon, learn more about the unique Piazza Navona, and immerse yourself in the vibrant atmosphere of St. Peter's Basilica.

As you hit the open road and drive through Genoa, Corniglia, Riomaggiore, Manarola, Vernazza, Florence, Siena, Rome, and Pisa, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.

Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!

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Itinerary summary

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Days
Destination
Attractions
Overnight
Day
City & Overnight
Attractions
piazza De Ferrari
Aquarium of GenoaPalazzo Spinola National GalleryPalazzo BiancoVia GaribaldiPalazzo PodestàLighthouse of Genoa
Sentiero AzzurroChiesa Di San PietroScalinata Lardarina
RiomaggioreManarola Overlook ViewpointRuins of Doria TowerChurch of St. Margaret of Antioch
Ponte VecchioUffizi GalleryPalazzo Vecchiopiazza della Signoria
Basilica of Santa Croce in FlorenceGiotto's Bell TowerCathedral of Santa Maria del FioreGalleria dell'AccademiaRiccardi Medici PalaceCentral Market

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Day 1

Day 1

  • Genoa - Arrival day
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  • piazza De Ferrari
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Your road trip adventure in Italy begins as soon as you reach Genoa and pick up your car. You’ll stay in Genoa for 2 nights and explore the best things to see and do, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.

Genoa is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Piazza De Ferrari, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Make your way to your chosen hotel. Check-in typically starts between 2 and 4 PM in Genoa. Make yourself at home and enjoy some downtime before heading out again.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Genoa, it's often a good idea to reserve a table in advance.

Treat yourself to a delightful dinner at 7 Sensi cucina decontaminata, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Alla Lunga Ristorante? It's another excellent option with a diverse menu. Consider reserving a table at Grand Hotel Savoia as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Genoa.

Keep the evening going at Scurreria Beer & Bagel, a great choice for enjoying the after-dinner hours with a drink. You could also go to La Lepre, which offers a similarly pleasant setting and great drinks. Another option is Bar Pisacane Iii, which provides an inviting environment for unwinding after a busy day out.

Raise a toast to the start of your 12-day road trip in Italy!

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Day 2

Day 2

  • Genoa
  • More

Drive 16 km, 56 min

  • Aquarium of Genoa
  • Palazzo Spinola National Gallery
  • Palazzo Bianco
  • Via Garibaldi
  • Palazzo Podestà
  • Lighthouse of Genoa
  • More

Day 2 of your road trip across Italy promises a magnificent time exploring Genoa. You have 1 night left in Genoa. Take the opportunity to experience more of the best attractions and activities in the city.

Today’s itinerary in Genoa covers several incredible sights, including an aquarium, an art gallery, a street, a palace, a lighthouse and much more! Start your adventure at Aquarium Of Genoa. This extraordinary aquarium is a place that is appreciated by travelers and locals alike. Next, immerse yourself in the respected wonders of Palazzo Spinola National Gallery, a must-see art gallery in the city.

Consider stopping for a small bite to eat or a drink at a local eatery to keep your energy going. When you’re ready, continue your discovery with a visit to Palazzo Bianco. This worthwhile art gallery offers an enriching experience. For a change of pace, head to Via Garibaldi, where you can take in UNESCO world heritage-designated features. Conclude your self-guided sightseeing tour with a visit to Palazzo Podestà and Lighthouse Of Genoa. These sights offer a fulfilling end to a perfect day.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Genoa. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Treat yourself to a delightful dinner at Zeffirino, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Trattoria Vegia Zena? It's another excellent option with a diverse menu. Consider reserving a table at Trattoria delle Grazie as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Genoa.

Get a good night's sleep and look forward to another great day on the road in Italy!

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Day 3

Day 3

  • Genoa
  • Corniglia
  • More

Drive 113 km, 2 hours 7 min

  • Sentiero Azzurro
  • Chiesa Di San Pietro
  • Scalinata Lardarina
  • More

On day 3 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Corniglia. In the evening, you’ll end up in Corniglia, where you will stay for 2 nights.

Set out on a day brimming with family-friendly attractions, romantic experiences, and natural wonders. Start at the often recommended Sentiero Azzurro, a mesmerizing hiking area in Genoa. Next, go to Chiesa Di San Pietro.

After visiting Sentiero Azzurro and Chiesa Di San Pietro, have a stroll along Genoa's streets and take in the local charm. Continue your sightseeing by heading to Scalinata Lardarina. This enchanting hiking area offers a unique experience.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Corniglia. Corniglia offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Corniglia. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Savor the flavors at La Scuna Wine & Beer, a top pick for dinner tonight. Alternatively, Enoteca Il Pirun beckons with its unique menu offerings. Also, consider A Cantina da Mananan. With its consistent customer satisfaction, it’s an excellent option for dining in Corniglia tonight.

After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at Caffè Matteo Snc Di Galletti Riccardo E Rizzuti Manuela, a well-loved spot among locals and tourists.

Take some time to reflect on your day and savor another beautiful night in Italy.

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Day 4

Day 4

  • Corniglia
  • More

Drive 38 km, 2 hours 6 min

  • Riomaggiore
  • Manarola Overlook Viewpoint
  • Ruins of Doria Tower
  • Church of St. Margaret of Antioch
  • More

On day 4 of your road trip, you’ll start and end your day in Corniglia, but spend part of the day exploring places of interest outside the immediate village. On today's itinerary, you'll find attractions in Riomaggiore, Manarola, and Vernazza. You still have 1 night left in Corniglia.

Immerse yourself in Corniglia’s rich culture with today's sightseeing itinerary. Start your journey at Riomaggiore. Next, dive into the romantic features of Manarola Overlook Viewpoint, a must-visit observation deck in the village.

In between sights, stop by local stores, picturesque photo spots, and small eateries. When you’re ready for your next attraction, proceed to Ruins Of Doria Tower, an increasingly popular monument. For a change of scene, check out Church Of St. Margaret Of Antioch, known for its historic features.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Corniglia.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Corniglia. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Treat yourself to a wonderful meal at Il Buongustaio Cucina Casalinga, a top-rated dining spot in Corniglia. If you're in the mood for something new, try Ristorante La Posada, another premier location with a delectable menu. You might also want to book a table at Marina di Corniglia. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Corniglia.

Take some time to reflect on your day and savor another beautiful night in Italy.

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Day 5

Day 5

  • Corniglia
  • Florence
  • More

Drive 178 km, 2 hours 40 min

  • Ponte Vecchio
  • Uffizi Gallery
  • Palazzo Vecchio
  • piazza della Signoria
  • More

Experience an unparalleled adventure on day 5 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 vibrant destinations - Florence. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Florence. You will spend 3 nights here for some well-deserved relaxation.

Enjoy the perfect balance of relaxation and exploration in Corniglia today. One of the most world-famous attractions included on the itinerary is Ponte Vecchio. This romantic historical landmark will help you start your sightseeing on top. Then, take a leisurely stroll to Uffizi Gallery and learn what makes this historic art gallery unique.

Throughout the day, make sure to take breaks to appreciate the surroundings. Next up, visit the notable Palazzo Vecchio. After exploring the palace, head to Piazza Della Signoria. This extraordinary public square is a highlight in Corniglia.

At the end of the day, you will drive to Florence, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you explore more of Florence, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Treat yourself to a wonderful meal at Ristorante Oliviero 1962, a top-rated dining spot in Florence. If you're in the mood for something new, try Di Poneta Novoli, another premier location with a delectable menu. You might also want to book a table at Caffe San Firenze. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Florence.

Round off your dining experience by visiting Manifattura, a prime location for a drink. Alternatively, explore the distinctive characteristics of Se·sto On Arno Rooftop Bar, a bar catering to every mood and preference. Il Vinile likewise offers a unique atmosphere, perfect for a memorable night out.

Say good night to Florence and look forward to another great day of your road trip in Italy!

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Day 6

Day 6

  • Florence
  • More

Drive 3 km, 51 min

  • Basilica of Santa Croce in Florence
  • Giotto's Bell Tower
  • Cathedral of Santa Maria del Fiore
  • Galleria dell'Accademia
  • Riccardi Medici Palace
  • Central Market
  • More

On day 6 of your road trip, you will have an entire day to explore Florence. You’ll stay in Florence for 2 nights and discover all the best things to see and do in the area.

Set out on a day brimming with family-friendly attractions, picturesque spots, and history-rich sites. Start at the popular Basilica Of Santa Croce In Florence, a heritage-rich church in Florence. Next, go to Giotto's Bell Tower.

After visiting Basilica Of Santa Croce In Florence and Giotto's Bell Tower, have a stroll along Florence's streets and take in the local charm. Continue your sightseeing by heading to Cathedral Of Santa Maria Del Fiore. This history-steeped church offers a unique experience. Galleria Dell'accademia is another noteworthy attraction worthwhile a visit. End your self-guided sightseeing tour on top with a visit to Riccardi Medici Palace, one of the most photogenic places to visit in Florence. If you still have some time left for sightseeing, we also recommend stopping by Central Market.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

Indulge in a memorable dining experience at one of Florence's most popular restaurants, and connect with friendly locals for an authentic adventure.

Enjoy a delicious meal at Ditta Artigianale, a highly-rated dining destination in Florence. If you're eager to try something different, consider Trattoria Da Burde, another top spot with a tantalizing menu. You might also want to secure a reservation at Casa Toscana. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Florence this evening.

After enjoying a fulfilling meal, continue your evening at Bar 50 Rosso, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, Bitter Bar offers a welcoming atmosphere for easing into the nightlife. Similarly, Archea Brewery provides an excellent environment for a relaxed and enjoyable evening.

Raise your glass to another unforgettable day in Italy!

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Day 7

Day 7

  • Florence
  • More

Drive 154 km, 2 hours 36 min

  • Siena Cathedral
  • Battistero di San Giovanni Battista
  • piazza del Campo
  • Tower of Mangia
  • More

Wake up to day 7 of your extraordinary road trip in Italy. With 1 night left in Florence, we encourage you to seize the day and discover the unexplored beauty of the city’s surroundings!

Get ready for a day filled with fun adventures, romantic experiences, and scenic views in the charming city of Florence. Your adventure starts at Siena Cathedral, an interesting local hot spot. Another notable attraction to explore is Battistero Di San Giovanni Battista. This intriguing church is known for its majestic appeal.

After soaking in the highlights of these sights, take some time to wander Florence's streets and immerse yourself in the local atmosphere. When you're ready to continue your sightseeing adventure, head to Piazza Del Campo. This romantic public square offers a fascinating experience that many visitors find memorable. Tower Of Mangia is also worth visiting.

When you’re done exploring for the day, you’ll return to Florence and your accommodation.

After a day of adventure, treat yourself to an exquisite dinner at one of Florence's best restaurants.

Enjoy a delicious meal at Ristorante Buca Mario, a top-rated dining destination in Florence. If you're in the mood to try something new, consider Agricola Toscana, another top spot with a mouthwatering menu. You might also want to secure a reservation at Eataly Firenze. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Florence this evening.

If you’re not ready to end the night just yet, Gosh* offers a perfect venue to relax and savor a drink. Similarly, Antico Caffè Del Moro - Art Bar Firenze is well-suited for those looking to unwind in a social setting. Quelo Bar is another excellent spot to enjoy a nightcap after a delightful meal.

Savor another day of unforgettable experiences in Italy!

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Day 8

Day 8

  • Florence
  • Rome
  • More

Drive 279 km, 3 hours 46 min

  • Basilica di Santa Maria Maggiore
  • Spanish Steps
  • Piazza di Spagna
  • Trevi Fountain
  • Altare della Patria
  • More

Dive into day 8 of your remarkable road trip in Italy. Today you will explore Rome, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Rome. You’ll stay here for 3 nights.

Discover a day packed with fun adventures, picturesque spots, and history-rich sites in Florence. Begin your sightseeing with Basilica Di Santa Maria Maggiore. This notable church is one of the top attractions in the city. Proceed to Spanish Steps, another must-visit attraction.

As you wander through the inviting streets of Florence, soak in the lively ambiance and take the opportunity to snap some photos. Next, head to Piazza Di Spagna. This world-famous public square is a traveler-favorite. Not far away, you’ll find Trevi Fountain, another key site on your sightseeing itinerary. Altare Della Patria is yet another highly recommended place to visit nearby, offering plenty to discover for curious travelers.

When you’re done exploring for the day, you’ll drive to your hotel in Rome. Check in and spend some time relaxing before you head out to tour the city.

Indulge in a memorable dining experience at one of Rome's most popular restaurants, and connect with friendly locals for an authentic adventure.

Enjoy a lovely dining experience at La Bottega Roma, a popular restaurant in Rome. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Rome at Pasta In Corso, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated Trattoria Vecchia Roma. It’s yet another ideal choice to enhance your time in Rome tonight.

Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, La Botticella Of Poggi Giovanni stands out as an excellent choice for a post-dinner cocktail. Alternatively, Almalu Trastevere offers an ideal atmosphere to enjoy the pleasures of the night. Bar Viminale Di Pepi Maurilio is also a great option that provides a perfect setting for a relaxing evening.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in Italy.

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Day 9

Day 9

  • Rome
  • More

Drive 10 km, 1 hour 22 min

  • Colosseum
  • Roman Forum
  • Pantheon
  • Piazza Navona
  • Campo de' Fiori
  • Castel Sant'Angelo
  • More

Day 9 of your road trip will take you to the best attractions Rome has to offer. Cherish the 2 nights you have left in Rome by discovering the best things there are to see and do in the city.

Get ready for a day filled with fun adventures, scenic views, and photo-friendly spots in the charming city of Rome. Your adventure starts at Colosseum, a wondrous local hot spot. Another notable attraction to explore is Roman Forum. This globally renowned archeological site is known for its culturally significant appeal.

After soaking in the highlights of these sights, take some time to wander Rome's streets and immerse yourself in the local atmosphere. When you're ready to continue your sightseeing adventure, head to Pantheon. This culturally significant monument offers a fascinating experience that many visitors find memorable. Piazza Navona is also worth visiting, along with Campo De' Fiori. These standout landmarks offer unique experiences that add to the day’s enjoyment. End your day at Castel Sant'angelo. This famous castle provides a fitting finale to your sightseeing.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

As you explore more of Rome, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Enjoy a lovely meal at RomAntica, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Coso Ristorante is another top choice with a popular menu. You could also check for a table at DEROMA - Farine Romane. As an establishment that gains consistently high praises from customers, it’s an ideal choice in Rome tonight.

To truly maximize your evening out, consider visiting Sant' Eustachio Caffè after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to Yellowsquare Rome, another bar with an inviting ambiance. Similarly, Caffè Portofino also offers a great atmosphere, ensuring a night filled with enjoyment and relaxation.

Savor another day of unforgettable experiences in Italy!

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Day 10

Day 10

  • Rome
  • More

Drive 13 km, 1 hour 5 min

  • Vatican Museums
  • Saint Peter's Square
  • Sistine Chapel
  • St Peter's Basilica
  • Belvedere del Gianicolo
  • Trastevere
  • More

On day 10 of your road trip in Italy, you’ll start and end your day in Rome, but spend the day exploring what’s beyond the city. Since you will return to Rome for 1 night more, there’s no need to rush. Experience Vatican City and Rome to the fullest today with this curated day itinerary!

Make sure to visit Trastevere, a popular neighborhood in Vatican City. Spend some time wandering around the area and soak in its distinctive charm. You’ll also discover that several of the city’s must-see attractions are just around the corner.

Start your adventure at Vatican Museums. This iconic art museum is a must-visit for travelers looking for a unique holiday experience. Make your way to Saint Peter's Square located in Rome for another exciting encounter.

Next, immerse yourself in the setting of Sistine Chapel. After the chapel, continue your tour of the city with a visit to St. Peter's Basilica. Next up is Belvedere Del Gianicolo, a highly recommended observation deck.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Rome.

As you explore more of Rome, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Have a fantastic dining experience at Hotel de Russie, a highly recommended choice for tonight's dinner. If you're looking to mix things up, La Taverna Italiana offers an enticing alternative with its varied menu. Additionally, The Parrot Bar is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Rome.

Unwind after your meal by stepping into The Apartment Bar Roma. This venue is celebrated for its extensive drink selections and cozy vibes. Alternatively, Hotel Hassler Roma offers a dynamic and energetic atmosphere for a glass or two.

Head back to your accommodation in Rome and get some rest in preparation for another magical day of your road trip in Italy!

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Day 11

Day 11

  • Rome
  • Genoa
  • More

Drive 498 km, 5 hours 58 min

  • Leaning Tower of Pisa
  • Piazza del Duomo, Pisa
  • Campo santo
  • More

On day 11 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, Pisa. When you’re not sightseeing, take time to relax at your selected hotel in Genoa, where you’ll be staying for 1 night.

A blend of family-friendly attractions, scenic views, and photo-friendly spots await you in Rome on today’s itinerary. First up is the wondrous monument, Leaning Tower Of Pisa. Afterward, continue to Piazza Del Duomo, Pisa, a public square every traveler should visit.

As you explore Rome’s charming streets, take in the lively atmosphere and get to know the character of the city. Next, make your way to Campo Santo. This locally appreciated cemetery is an essential stop.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Genoa. Genoa offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As dinnertime approaches, it's time to head out for a bite to eat in Genoa. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Enjoy a delicious meal at Osteria Sant'Ilario, a highly-rated dining destination in Genoa. If you're eager to try something different, consider La Cialtroneria, another top spot with a tantalizing menu. You might also want to secure a reservation at Manhattan Bar. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Genoa this evening.

Raise your glass to another unforgettable day in Italy!

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Day 12

Day 12

  • Genoa - Departure day
  • More
  • Chiesa di San Giorgio
  • More

Day 12 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Genoa before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, we recommend visiting Chiesa Di San Giorgio, a heritage-rich church before you head out.

Explore local shops for souvenirs to remember your trip or find unique gifts for loved ones.

Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Genoa.

You’ll then say farewell to Genoa. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!

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