12-Day Italy Self-Drive Road Trip With Itinerary from Genoa traveling east to Corniglia, Florence, and Rome

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Photo of Sand beach in Camogli by Genoa, Italy.
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Escape the ordinary with this exciting 12-day road trip through Italy. Explore diverse landscapes, discover lively cities, and prepare for an unforgettable journey!

This perfectly planned road trip itinerary takes you through some of the best places to see in Italy. You will spend 3 nights in Genoa, 2 nights in Corniglia, 3 nights in Florence, and 3 nights in Rome. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Genoa, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Trevi Fountain and Colosseum are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Pantheon, learn more about the unique Piazza Navona, and immerse yourself in the vibrant atmosphere of St. Peter's Basilica.

As you hit the open road and drive through Genoa, Corniglia, Riomaggiore, Manarola, Vernazza, Florence, Siena, Rome, and Pisa, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.

Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!

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Day 1

Day 1

  • Genoa - Arrival day
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  • piazza De Ferrari
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Welcome to Genoa, the perfect starting point for your road trip in Italy! Pick up your rental car and let the adventure begin. You will spend 2 nights discovering what to see in Genoa before embarking on the next leg of your journey.

Genoa is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Piazza De Ferrari, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Find your way to your hotel in Genoa. We recommend choosing a hotel in a central location for easy exploring. Check-in typically starts between 2 and 4 PM at hotels in Italy. Settle in and make plans for the evening.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Genoa, it's often a good idea to reserve a table in advance.

Enjoy a lovely meal at 7 Sensi cucina decontaminata, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Alla Lunga Ristorante is another top choice with a popular menu. You could also check for a table at Grand Hotel Savoia. As an establishment that consistently gains high praises from customers, it’s an ideal choice in Genoa tonight.

Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, Scurreria Beer & Bagel stands out as an excellent choice for a post-dinner cocktail. Alternatively, La Lepre offers an ideal atmosphere to enjoy the pleasures of the night. Bar Pisacane Iii is also a great option that provides a perfect setting for a relaxing evening.

Raise a toast to the start of your 12-day road trip in Italy!

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Day 2

Day 2

  • Genoa
  • More

Drive 16 km, 56 min

  • Aquarium of Genoa
  • Palazzo Spinola National Gallery
  • Palazzo Bianco
  • Via Garibaldi
  • Palazzo Podestà
  • Lighthouse of Genoa
  • More

Day 2 of your road trip across Italy promises a magnificent time exploring what to see in Genoa. You have 1 night left in Genoa. Take the opportunity to experience more of the best attractions and activities in the city.

Catch Aquarium Of Genoa before the crowds roll in. This gorgeous aquarium is sure to ignite your curiosity. Next, dive into the respected features of Palazzo Spinola National Gallery, a must-visit art gallery in the city.

In between sights, stop by local stores, picturesque photo spots, and small eateries. When you’re ready for your next attraction, proceed to Palazzo Bianco, a curiosity-inducing art gallery. For a change of scene, check out Via Garibaldi, known for its visually striking features. We also recommend visiting Palazzo Podestà. This palace is a must for anyone looking to experience the city to the fullest. Lastly, end your day with a visit to Lighthouse Of Genoa, yet another underrated attraction in Genoa.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Genoa, it's often a good idea to reserve a table in advance.

Enjoy a lovely meal at Zeffirino, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Trattoria Vegia Zena is another top choice with a popular menu. You could also check for a table at Trattoria delle Grazie. As an establishment that consistently gains high praises from customers, it’s an ideal choice in Genoa tonight.

Head back to your accommodation in Genoa and get some rest to prepare for another magical day of your road trip in Italy.

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Day 3

Day 3

  • Genoa
  • Corniglia
  • More

Drive 113 km, 2 hours 7 min

  • Sentiero Azzurro
  • Chiesa Di San Pietro
  • Scalinata Lardarina
  • More

On day 3 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, including Corniglia. When you’re not sightseeing, take time to relax at your chosen hotel in Corniglia, where you’ll be staying for 2 nights.

To truly experience Genoa, make sure to drop by Sentiero Azzurro. This frequently visited hiking area is a must-visit for anyone seeking a unique vacation experience. Another sight you shouldn’t miss is Chiesa Di San Pietro, one of the village’s best highlights.

Next, check out Scalinata Lardarina, one of the most frequently visited places to see in Genoa. This hiking area is a favorite among locals and travelers alike.

At the end of the day, you will drive to Corniglia, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

Corniglia is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Corniglia.

Have a fantastic dining experience at La Scuna Wine & Beer, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Enoteca Il Pirun offers an enticing alternative with its varied menu. Additionally, A Cantina da Mananan is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Corniglia.

Let the evening flow smoothly from dinner to drinks at Caffè Matteo Snc Di Galletti Riccardo E Rizzuti Manuela, a top-rated bar in the area.

As the sun sets, rest up and recharge for the next leg of your road trip in Italy.

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Day 4

Day 4

  • Corniglia
  • More

Drive 38 km, 2 hours 6 min

  • Riomaggiore
  • Manarola Overlook Viewpoint
  • Ruins of Doria Tower
  • Church of St. Margaret of Antioch
  • More

On day 4 of your road trip in Italy, you’ll start and end your day in Corniglia, but spend the day exploring what’s beyond the village. Since you still have 1 night to spend in Corniglia, there’s no need to rush. Experience Riomaggiore, Manarola, and Vernazza to the fullest today with this curated day itinerary.

No visit to Corniglia is complete without Riomaggiore. This often recommended sightseeing destination is one of the top attractions in the village. Proceed to Manarola Overlook Viewpoint, another must-visit attraction.

As you wander through the inviting streets of Corniglia, soak in the lively ambiance and take the opportunity to snap some photos. Next, head to Ruins Of Doria Tower. This underrated monument is a traveler-favorite. Not far away, you’ll find Church Of St. Margaret Of Antioch, another key site on your sightseeing itinerary.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Corniglia.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Corniglia. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Make sure to reserve a table at Il Buongustaio Cucina Casalinga, an iconic dining spot in Corniglia. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Ristorante La Posada, a popular restaurant in Corniglia. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Marina di Corniglia, a hidden gem nestled in Corniglia. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Celebrate another amazing day of your road trip adventure in Italy!

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Day 5

Day 5

  • Corniglia
  • Florence
  • More

Drive 178 km, 2 hours 40 min

  • Ponte Vecchio
  • Uffizi Gallery
  • Palazzo Vecchio
  • piazza della Signoria
  • More

Experience an unparalleled adventure on day 5 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 place, which are Florence. At the end of the day, you will retreat to the hotel of your choice in Florence, where will spend 3 nights.

Your adventure in Corniglia is only getting started when you visit Ponte Vecchio, a timeless local hot spot. Another notable attraction to explore is Uffizi Gallery. This extraordinary art gallery is known for its visually striking appeal.

After soaking in the highlights of these sights, take some time to wander Corniglia's streets and immerse yourself in the local atmosphere. When you're ready to continue your sightseeing adventure, head to Palazzo Vecchio. This romantic palace offers a fascinating experience that many visitors find memorable. Piazza Della Signoria is also worth visiting.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Florence. Florence offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

Indulge in a memorable dining experience at one of Florence's most popular restaurants, and connect with friendly locals for a true cultural experience.

Make sure to reserve a table at Ristorante Oliviero 1962, an iconic dining spot in Florence. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Di Poneta Novoli, a popular restaurant in Florence. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Caffe San Firenze, a hidden gem nestled in Florence. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, Manifattura stands out as an excellent choice for a post-dinner cocktail. Alternatively, Se·sto On Arno Rooftop Bar offers an ideal atmosphere to enjoy the pleasures of the night. Il Vinile is also a great option that provides a perfect setting for a relaxing evening.

Savor another day of unforgettable experiences in Italy!

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Day 6

Day 6

  • Florence
  • More

Drive 3 km, 51 min

  • Basilica of Santa Croce in Florence
  • Giotto's Bell Tower
  • Cathedral of Santa Maria del Fiore
  • Galleria dell'Accademia
  • Riccardi Medici Palace
  • Central Market
  • More

Day 6 offers an itinerary packed with the best things to see in Florence. You’ll stay in Florence for 2 nights more, offering you enough time to explore at a relaxed pace.

Basilica Of Santa Croce In Florence brings Florence's character to life. This culturally significant church is a highlight of any visit in the city. Then, enjoy Giotto's Bell Tower, another enchanting attraction that never fails to captivate visitors. Next, head over to Cathedral Of Santa Maria Del Fiore, one of the city’s most spectacular attractions, known for its inviting features.

If you’re looking for more, spend time soaking in the atmosphere of Galleria Dell'accademia. This photogenic art gallery is frequented by locals and tourists alike. To complete your memorable day, make sure to visit Riccardi Medici Palace, an underrated palace, and take a stroll around the area. If you want to extend your self-guided sightseeing tour, go check out Central Market before you head back to your hotel.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

Florence is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Florence.

Enjoy a delicious meal at Ditta Artigianale, a top-rated dining destination in Florence. If you're in the mood to try something new, consider Trattoria Da Burde, another top spot with a mouthwatering menu. You might also want to secure a reservation at Casa Toscana. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Florence this evening.

Keep the evening going at Bar 50 Rosso, a great choice for enjoying the after-dinner hours with a drink. You could also go to Bitter Bar, which offers a similarly pleasant setting and great drinks. Another option is Archea Brewery, which provides an inviting environment for unwinding after a busy day out.

Relax and recharge in preparation for another adventurous day in Italy!

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Day 7

Day 7

  • Florence
  • More

Drive 154 km, 2 hours 36 min

  • Siena Cathedral
  • Battistero di San Giovanni Battista
  • piazza del Campo
  • Tower of Mangia
  • More

On day 7 of your road trip, you’ll start and end your day in Florence, where you still have 1 night left. You'll spend part of the day exploring places of interest outside the immediate city, including Siena.

Make time for Siena Cathedral, a captivating church that is worthwhile a visit in the city. Nearby, you’ll find Battistero Di San Giovanni Battista, enchanting visitors with its culturally significant appeal. Continue your exploration at Piazza Del Campo. This public square is one of the city’s most famous spots.

Enjoy the freedom of exploring Florence at your own pace and find hidden gems along the way. If you want to see more picture-perfect spots, make sure to visit Tower Of Mangia.

When you’re done exploring for the day, you’ll return to Florence and your accommodation.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Florence, it's often a good idea to reserve a table in advance.

Enjoy a lovely meal at Ristorante Buca Mario, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Agricola Toscana is another top choice with a popular menu. You could also check for a table at Eataly Firenze. As an establishment that consistently gains high praises from customers, it’s an ideal choice in Florence tonight.

Let the evening flow smoothly from dinner to drinks at Gosh*, a top-rated bar in the area. For other recommendations, Antico Caffè Del Moro - Art Bar Firenze provides a perfect setting for rounding out your night with style and great drinks. Likewise, Quelo Bar offers a memorable night with diverse drink options and excellent service.

Relax and recharge in preparation for another adventurous day in Italy!

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Day 8

Day 8

  • Florence
  • Rome
  • More

Drive 279 km, 3 hours 46 min

  • Basilica di Santa Maria Maggiore
  • Spanish Steps
  • Piazza di Spagna
  • Trevi Fountain
  • Altare della Patria
  • More

Dive into day 8 of your remarkable road trip in Italy. Today you'll explore 1 destination, including Rome. At the end of the day, you’ll unwind at one of the finest accommodations in Rome, where you'll spend 3 nights.

Look forward to a unique sightseeing adventure at the notable Basilica Di Santa Maria Maggiore and allow yourself time to explore. Just a short distance away you'll find your next stop, Spanish Steps, a respected public square that draws visitors from far and near.

Continue your journey to Piazza Di Spagna, one of the city’s most globally renowned spots that you shouldn’t miss. Another great site to visit is the iconic Trevi Fountain. When you're finished at the monument, Altare Della Patria awaits your visit. This monument is a picture-perfect highlight on today's itinerary.

When you’re done exploring for the day, you’ll drive to your hotel in Rome. Check in and relax before you head out to tour the city.

After a day of adventure, treat yourself to an exquisite dinner at one of Rome's best restaurants.

Treat yourself to a delightful dinner at La Bottega Roma, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Pasta In Corso? It's another excellent option with a diverse menu. Consider reserving a table at Trattoria Vecchia Roma as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Rome.

Cap off your dinner by heading to La Botticella Of Poggi Giovanni, ideal for a leisurely evening with a drink in hand. Almalu Trastevere is another bar that offers an enjoyable setting. Similarly, Bar Viminale Di Pepi Maurilio is also a popular place to go on a night out, perfect for relaxing and socializing.

Relax and recharge in preparation for another adventurous day in Italy!

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Day 9

Day 9

  • Rome
  • More

Drive 10 km, 1 hour 22 min

  • Colosseum
  • Roman Forum
  • Pantheon
  • Piazza Navona
  • Campo de' Fiori
  • Castel Sant'Angelo
  • More

Day 9 of your road trip will take you to the best attractions Rome has to offer. Cherish the 2 nights you have left in the city and use the provided itinerary to discover what to see in Rome.

Colosseum makes a great addition to your morning plans. This iconic archeological site is an UNESCO world heritage-listed place to see in Rome. Continue your discovery at Roman Forum, a picture-perfect archeological site with stories to tell.

As you stroll around Rome, take in the distinct atmosphere and learn what makes this city so unique. Maximize your sightseeing with a visit to Pantheon. This wondrous monument offers a culturally significant encounter with Rome. Next, make your way to Piazza Navona to add another highlight to your day. After that, visit Campo De' Fiori, a widely recognized public square that’s sure to impress. If you’re up for more, end your self-guided sightseeing tour at Castel Sant'angelo, an impressive castle in the city. Whether you decide to get entrance tickets for all attractions or you prefer admiring from a distance, amazing experiences await on this day in Rome.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Rome. Enjoy a relaxing evening as you savor delicious local cuisine.

Enjoy a delicious meal at RomAntica, a highly-rated dining destination in Rome. If you're eager to try something different, consider Coso Ristorante, another top spot with a tantalizing menu. You might also want to secure a reservation at DEROMA - Farine Romane. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Rome this evening.

Following your dinner, dive into the local bar culture at Sant' Eustachio Caffè. Enjoy this evening's relaxed ambiance with delightful drinks. Alternatively, go to Yellowsquare Rome, the perfect place for those looking to experience the best of the nightlife. Similarly, Caffè Portofino provides excellent drinks and a great atmosphere, ensuring a memorable night out.

Say good night to Rome and look forward to another great day of your road trip in Italy!

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Day 10

Day 10

  • Rome
  • More

Drive 13 km, 1 hour 5 min

  • Vatican Museums
  • Saint Peter's Square
  • Sistine Chapel
  • St Peter's Basilica
  • Belvedere del Gianicolo
  • Trastevere
  • More

On day 10 of your road trip, you'll get the chance to experience Vatican City and Rome. At the end of the day, you'll drive back to Rome, where you still have 1 night left to stay.

Vatican City is brimming with adventures. Trastevere is a neighborhood that stands out as one of the must-see places in Vatican City. Take a moment to explore its distinct atmosphere, and don’t miss the popular sightseeing spots just a short walk away.

Vatican Museums is an ideal stop early in the day. This globally renowned art museum is a must-visit in the city.

One of the best things about exploring Rome on a self-guided tour is that you set the pace. There’s plenty of time for detours and discovering hidden gems. When you’re ready for your next stop, make your way to Sistine Chapel, a top-rated chapel in the city. If you’re up for more discoveries, don’t forget to reserve some time for St. Peter's Basilica and Belvedere Del Gianicolo.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Rome.

After a day of adventure, treat yourself to an exquisite dinner at one of Rome's best restaurants.

Treat yourself to a delightful dinner at Hotel de Russie, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try La Taverna Italiana? It's another excellent option with a diverse menu. Consider reserving a table at The Parrot Bar as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Rome.

Continue your evening by exploring the vibrant nightlife scene at The Apartment Bar Roma, a prime destination for a thrilling night out. Also, don’t forget to check out Hotel Hassler Roma, a bar that offers unique local touches.

Raise your glass and celebrate another amazing day of your road trip in Italy!

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Day 11

Day 11

  • Rome
  • Genoa
  • More

Drive 498 km, 5 hours 58 min

  • Leaning Tower of Pisa
  • Piazza del Duomo, Pisa
  • Campo santo
  • More

Your itinerary for day 11 of your road trip in Italy includes 1 stop and features some of the highlights of Pisa. At the end of the day, enjoy the comforts of a top-rated hotel in Genoa, where you'll spend 1 night.

Visiting Leaning Tower Of Pisa is always a good idea. This globally renowned monument is a place that is appreciated by travelers and locals alike. Next, immerse yourself in the symbolic wonders of Piazza Del Duomo, Pisa, a must-see public square in the city.

Consider stopping for a small bite to eat or a drink at a local eatery to keep your energy going. When you’re ready, continue your discovery with a visit to Campo Santo. This frequently visited cemetery offers an enriching experience. These sights offer a fulfilling end to a perfect day.

At the end of the day, you will drive to Genoa, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Genoa. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Dine in style at Osteria Sant'Ilario, a top recommendation for dinner tonight. Or, for a change of pace, La Cialtroneria boasts a menu that's sure to impress. Also, be sure to check out Manhattan Bar. Known as a local hotspot, it’s a great choice for tonight in Genoa.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in Italy.

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Day 12

Day 12

  • Genoa - Departure day
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  • Chiesa di San Giorgio
  • More

Day 12 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Genoa before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, begin at Chiesa Di San Giorgio. This curiosity-inducing church is a hotspot among locals.

Make the most of your final day in Italy by visiting Genoa’s iconic markets and shopping establishments in the buzzing Via Garibaldi. Secure the perfect souvenirs for your family and friends back home or buy yourself a remembrance of your amazing vacation. You can also browse through boutiques for stylish fashion choices.

Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Genoa.

If you're in the mood to try something new, consider Trattoria Ugo, another top spot with a mouthwatering menu.

You’ll then say farewell to Genoa. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!

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Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
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Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

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