12-Day Italy Self-Drive Road Trip With Itinerary from Naples to Amalfi, Matera, Polignano a Mare, and Lecce

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Photo of Morning view of Amalfi cityscape on coast line of mediterranean sea, Italy.
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Escape the ordinary with this exciting 12-day road trip through Italy. Explore diverse landscapes, discover lively cities, and prepare for an unforgettable journey!

This perfectly planned road trip itinerary takes you through some of the best places to see in Italy. You will spend 3 nights in Naples, 2 nights in Amalfi, 2 nights in Matera, 2 nights in Polignano a Mare, and 2 nights in Lecce. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Naples, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Amalfi Coast and Piazza Del Plebiscito are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Archaeological Park Of Pompeii, learn more about the unique Sassi Di Matera, and immerse yourself in the vibrant atmosphere of Ovo Castle.

As you hit the open road and drive through Naples, Sorrento, Positano, Amalfi, Ravello, Minori, Pompei, Matera, Alberobello, Polignano a Mare, Lecce, Otranto, and Benevento, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.

Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!

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Day 1

Day 1

  • Naples - Arrival day
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  • piazza del Plebiscito
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Your road trip adventure in Italy begins as soon as you reach Naples and pick up your car. You’ll stay here for 2 nights and explore what to see in Naples, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.

Naples is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Piazza Del Plebiscito, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

As afternoon approaches, head to your chosen hotel in Naples. Check-in typically starts around 2 to 4 PM at hotels in Italy. We recommend staying at a central location for easy access to key areas in the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Naples, it's often a good idea to reserve a table in advance.

Enjoy a lovely meal at L'Oca Nera Irish Pub, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Mimì alla Ferrovia is another top choice with a popular menu. You could also check for a table at Spuzzulè Winebar. As an establishment that consistently gains high praises from customers, it’s an ideal choice in Naples tonight.

Extend your evening after a delightful meal by visiting Happening Cocktail Bar, which offers the perfect atmosphere for a night out. Moreover, Shanti Art Musik Bar is another popular option for a drink or two. Likewise, Gran Caffè Gambrinus also provides a great ambiance for reminiscing about the day and raising a toast to your vacation.

Raise a toast to the start of your 12-day road trip in Italy!

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Day 2

Day 2

  • Naples
  • More

Drive 10 km, 1 hour 12 min

  • Cappella Sansevero
  • Naples National Archaeological Museum
  • Ovo Castle
  • Chiaia
  • Quartiere Spagnolo
  • More

On day 2 of your road trip, you will have an entire day to discover what to see in Naples. You’ll stay in Naples for 1 night.

Chiaia is a fantastic place you can explore today in Naples. This neighborhood is a testament to the city’s character, and it's easy to spend hours just walking around and admiring the surroundings. Soak in the Naples-way-of-life and visit all the nearby sights. You should also check out Quartiere Spagnolo, a neighborhood offering more opportunities to enjoy the city’s vibrant atmosphere and landmarks.

Make a stop at Cappella Sansevero. This well-known museum is a must-visit for travelers looking for a unique holiday experience. Make your way to Naples National Archaeological Museum located in Naples for another exciting encounter.

Next, immerse yourself in the setting of Ovo Castle. Its symbolic features will captivate you.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Naples, it's often a good idea to reserve a table in advance.

Enjoy a lovely meal at Antica Pizzeria Di Matteo, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Mercure Napoli Centro Angioino is another top choice with a popular menu. You could also check for a table at La Lazzara Trattoria e Pizzeria. As an establishment that consistently gains high praises from customers, it’s an ideal choice in Naples tonight.

After enjoying a fulfilling meal, continue your evening at Archivio Storico - Cocktail Bar & Wonderfood, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, Archeobar offers a welcoming atmosphere for easing into the nightlife. Similarly, Babette Pub provides an excellent environment for a relaxed and enjoyable evening.

Savor another day of unforgettable experiences in Italy!

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Day 3

Day 3

  • Naples
  • Amalfi
  • More

Drive 83 km, 2 hours 40 min

  • Cathedral of Saints Philip and James
  • Parco di Villa Fiorentino
  • Villa Comunale di Sorrento
  • Costiera Amalfitana Positano
  • Chiesa di Santa Maria Assunta
  • More

On day 3 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 2 destinations, including Sorrento and Positano. When you’re not sightseeing, take time to relax at your chosen hotel in Amalfi, where you’ll be staying for 2 nights.

Cathedral Of Saints Philip And James leaves a lasting impression. This church is one of the most increasingly popular places to visit in Naples. Next, head to Parco Di Villa Fiorentino, a locally appreciated park, known for its romantic features.

In between the sights, don’t hesitate to take small detours to explore local stores and eateries. When you’re ready to continue your adventure, head to Villa Comunale Di Sorrento. This romantic park is a highly recommended experience. Nearby, you'll also find Costiera Amalfitana Positano and Chiesa Di Santa Maria Assunta. Visit these for an interesting touch to your journey.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Amalfi. Amalfi offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

Indulge in a memorable dining experience at one of Amalfi's most popular restaurants, and connect with friendly locals for a true cultural experience.

Have a fantastic dining experience at Pasticceria Pansa Amalfi, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Grand Hotel Excelsior Amalfi offers an enticing alternative with its varied menu. Additionally, Lido Azzurro is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Amalfi.

Cap off your dinner by heading to Bar Della Valle, ideal for a leisurely evening with a drink in hand.

Get a good night's sleep and look forward to another great day on the road in Italy!

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Day 4

Day 4

  • Amalfi
  • More

Drive 26 km, 1 hour 41 min

  • Amalfi Coast
  • Museum Of Paper
  • Villa Rufolo
  • Villa Cimbrone Gardens
  • Path of the Lemons
  • More

Wake up to day 4 of your road trip in Italy. On this day, you’ll embark on an exciting expedition discovering the enchanting sights and activities of Amalfi, Ravello, Castiglione, and Minori. With 1 night to stay in Amalfi, we encourage you to seize the day and discover the unexplored beauty of the village’s surroundings!

Amalfi is brimming with adventures.

Next, go to Museo Della Carta.

After visiting Amalfi Coast and Museo Della Carta, have a stroll along Amalfi's streets and take in the local charm. Continue your sightseeing by heading to Villa Rufolo. This enchanting historical landmark offers a unique experience. Villa Cimbrone Gardens is another noteworthy attraction worthwhile a visit. End your self-guided sightseeing tour on top with a visit to Path Of The Lemons, one of the most idyllic places to visit in Amalfi.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Amalfi.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Amalfi. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Dine in style at Ristorante Il Chiostro, a top recommendation for dinner tonight. Or, for a change of pace, Gerry's pub boasts a menu that's sure to impress. Also, be sure to check out Pizzeria Donna Stella. Known as a local hotspot, it’s a great choice for tonight in Amalfi.

Relax and recharge in preparation for another adventurous day in Italy!

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Day 5

Day 5

  • Amalfi
  • Matera
  • More

Drive 260 km, 4 hours 10 min

  • Archaeological Park of Pompeii
  • Lupanar des esclaves
  • Teatro Grande
  • Amphitheatre of Pompeii
  • Palombaro lungo
  • More

On day 5 of your road trip in Italy, your travel plans include 2 stops at the most scenic, wondrous, and interesting places in the region. Pompei and Matera are on today's agenda. In the evening, you’ll end up in Matera, where you will stay for 2 nights.

Archaeological Park Of Pompeii is must-visit archeological site and a great option for a daytime tour of the area. Continue your journey to Lupanare Di Pompei, an increasingly popular archeological site, located just a leisurely stroll away. Next, head to Teatro Grande, a standout archeological site, also available for your discovery today.

Each stop on today’s itinerary promises to leave you with lasting memories and a deeper appreciation for Amalfi. When you're ready, let your sightseeing route take you to the captivating Amphitheatre Of Pompeii. If you’re looking for more, Palombaro Lungo is also a beloved attraction that is worthwhile a visit.

When you’re done exploring for the day, you’ll drive to your hotel in Matera. Check in and relax before you head out to tour the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Matera, it's often a good idea to reserve a table in advance.

Treat yourself to a wonderful meal at Ristorante Le Bubbole, a top-rated dining spot in Matera.

Take some time to reflect on your day and savor another beautiful night in Italy.

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Day 6

Day 6

  • Matera
  • More

Drive 2 km, 31 min

  • Belvedere di Piazza Giovanni Pascoli
  • Casa Grotta nei Sassi di Matera
  • Sasso Caveoso
  • Sassi di Matera
  • Cattedrale di Maria Santissima della Bruna e Sant'Eustachio
  • More

Day 6 of your road trip will take you to the best attractions Matera has to offer. Cherish the 1 night you have left in the city and use the provided itinerary to discover what to see in Matera.

No visit to Matera is complete without Belvedere Di Piazza Giovanni Pascoli. This frequently visited observation deck is one of the top attractions in the city. Proceed to Casa Grotta Nei Sassi Di Matera, another must-visit attraction.

As you wander through the inviting streets of Matera, soak in the lively ambiance and take the opportunity to snap some photos. Next, head to Sasso Caveoso. This increasingly popular cave system is a traveler-favorite. Not far away, you’ll find Sassi Di Matera, another key site on your sightseeing itinerary. Cattedrale Di Maria Santissima Della Bruna E Sant'eustachio is yet another highly recommended place to visit nearby, offering plenty to discover for curious travelers.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

After a day of adventure, treat yourself to an exquisite dinner at one of Matera's best restaurants.

Enjoy a lovely dining experience at Baccanti, a popular restaurant in Matera. This acclaimed establishment has earned the admiration of countless food lovers in the city.

Raise your glass to another unforgettable day in Italy!

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Day 7

Day 7

  • Matera
  • Polignano a Mare
  • More

Drive 99 km, 2 hours 10 min

  • Trullo Siamese monumento negozio souvenir
  • Trulli di Alberobello Puglia
  • Museum of Contemporary Art Pino Pascali
  • Lungomare di Polignano a Mare
  • Cave of the Nuns
  • More

Your itinerary for day 7 of your road trip in Italy includes 2 stops and features some of the highlights of Alberobello and Polignano a Mare. At the end of the day, enjoy the comforts of a top-rated hotel in Polignano a Mare, where you'll spend 2 nights.

Your adventure in Matera is only getting started when you visit Trullo Siamese - Negozio Souvenirs, an up-and-coming local hot spot. Another notable attraction to explore is Trulli Di Alberobello Puglia. This popular historical landmark is known for its photogenic appeal.

After soaking in the highlights of these sights, take some time to wander Matera's streets and immerse yourself in the local atmosphere. When you're ready to continue your sightseeing adventure, head to Museum Of Contemporary Art Pino Pascali. This picture-perfect museum offers a fascinating experience that many visitors find memorable. Lungomare Di Polignano A Mare is also worth visiting, along with Cave Of The Nuns. These standout landmarks offer unique experiences that add to the day’s enjoyment.

At the end of the day, you will drive to Polignano a Mare, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Polignano a Mare. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Treat yourself to a delicious dinner at DA LUCIANO - La Puglia dentro, an excellent option for tonight's dining. Looking for something different? Grotta Palazzese offers a tantalizing alternative with its diverse menu. And don’t miss MINT Cucina Fresca. Known for great service, it’s a fantastic choice for tonight in Polignano a Mare.

Keep the excitement of the evening going by visiting a bar or two. Bella Blu Gelateria is an excellent place to start. You could also check out La Casa Del Mojito, offering a different kind of charm. A last recommendation for the day is Caffè Dei Serafini. This bar promises an enjoyable experience with tasty drinks and a vibrant setting.

Savor another day of unforgettable experiences in Italy!

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Day 8

Day 8

  • Polignano a Mare
  • More

Drive 7 km, 47 min

  • Calaponte Marina
  • Bastione di Santo Stefano
  • Centro Storico Polignano a Mare
  • Lama Monachile
  • Monumento a Domenico Modugno
  • More

On day 8 of your road trip, you’ll start and end your day in Polignano a Mare, where you still have 1 night left. You'll spend part of the day exploring places of interest outside the immediate town, including San Vito and Polignano a Mare.

Calaponte Marina is perfect for a self-paced visit during the day. This romantic marina is sure to impress. Next on your list is Bastione Di Santo Stefano, another must-visit landmark and increasingly popular historical landmark renowned for its history-steeped features.

While exploring and sightseeing, take time to savor the culture of Polignano a Mare by sampling some local delicacies. When you’re ready for more sightseeing, head to Centro Storico Polignano A Mare. This history-steeped public square is an essential place to visit for anyone looking for the full Polignano a Mare experience. We also recommend visiting Lama Monachile, a well-known beach. Nearby, you'll also find Monumento A Domenico Modugno, ready to add charm to your journey.

When you’re done exploring for the day, you’ll return to Polignano a Mare and your accommodation.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Polignano a Mare, it's often a good idea to reserve a table in advance.

Have a fantastic dining experience at Pescaria, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Il Pescato offers an enticing alternative with its varied menu. Additionally, Q8 is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Polignano a Mare.

Keep the excitement of the evening going by visiting a bar or two. The Super Mago Del Gelo Mario Campanella is an excellent place to start. You could also check out Bar Turismo, offering a different kind of charm.

Say good night to Polignano a Mare and look forward to another great day of your road trip in Italy!

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Day 9

Day 9

  • Polignano a Mare
  • Lecce
  • More

Drive 119 km, 1 hour 44 min

  • Porta Rudiae
  • Gate of Saint Blaise
  • Castello Carlo V
  • Giardini Pubblici Giuseppe Garibaldi - Villa Comunale
  • Basilica di Santa Croce
  • More

Experience an unparalleled adventure on day 9 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 place, which are Lecce. At the end of the day, you will retreat to the hotel of your choice in Lecce, where will spend 2 nights.

No visit to Polignano a Mare is complete without Porta Rudiae. This beloved monument is one of the top attractions in the city. Proceed to Gate Of Saint Blaise, another must-visit attraction.

As you wander through the inviting streets of Polignano a Mare, soak in the lively ambiance and take the opportunity to snap some photos. Next, head to Castle Of Charles V. This intriguing castle is a traveler-favorite. Not far away, you’ll find Giardini Pubblici Giuseppe Garibaldi - Villa Comunale, another key site on your sightseeing itinerary. Basilica Di Santa Croce is yet another highly recommended place to visit nearby, offering plenty to discover for curious travelers.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Lecce. Lecce offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a day of adventure, treat yourself to an exquisite dinner at one of Lecce's best restaurants.

Dine in style at Alle due Corti, a top recommendation for dinner tonight. Or, for a change of pace, Il Ristoro dei Templari Trattoria Pizzeria Braceria boasts a menu that's sure to impress. Also, be sure to check out La Cucina di Mamma Elvira. Known as a local hotspot, it’s a great choice for tonight in Lecce.

Let the evening flow smoothly from dinner to drinks at Sensi, a top-rated bar in the area. For other recommendations, Caffè Alvino provides a perfect setting for rounding out your night with style and great drinks. Likewise, Jolly Roger offers a memorable night with diverse drink options and excellent service.

Celebrate another amazing day of your road trip adventure in Italy!

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Day 10

Day 10

  • Lecce
  • More

Drive 97 km, 1 hour 39 min

  • Torre del Serpe
  • Aragonese Castle of Otranto
  • Lungomare degli Eroi
  • Spiaggia dei Gradoni
  • Cappella della Madonna dell'Altomare
  • More

On day 10 of your road trip in Italy, you’ll start and end your day in Lecce, but spend the day exploring what’s beyond the city. Since you still have 1 night to spend in Lecce, there’s no need to rush. Experience Otranto to the fullest today with this curated day itinerary.

Make a stop at Torre Del Serpe. This curiosity-inducing monument is a must-visit for travelers looking for a unique holiday experience. Make your way to Aragonese Castle Of Otranto located in Lecce for another exciting encounter.

Next, immerse yourself in the setting of Lungomare Degli Eroi. Its visually striking features will captivate you. After the public square, continue your tour of the town with a visit to Spiaggia Dei Gradoni. Visitors usually appreciate the romantic features of this beach. Next up is Cappella Della Madonna Dell'altomare, a highly recommended church.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Lecce.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Lecce. Enjoy a relaxing evening as you savor delicious local cuisine.

Enjoy a delicious meal at Miro Coffee Bistrot & Lounge Bar, a top-rated dining destination in Lecce. If you're in the mood to try something new, consider Oscar Cafè, another top spot with a mouthwatering menu. You might also want to secure a reservation at La Vecchia Osteria da Totu. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Lecce this evening.

Continue the enjoyment post-dinner at Bar Il Palio, a cherished local gathering spot renowned for its welcoming atmosphere. Similarly, Al Ventuno offers a vibrant space for indulging in well-crafted drinks and engaging conversation. You may also want to check out Avio. This bar is a favorite among both locals and visitors looking for a delightful evening out filled with laughter and fun.

Take some time to reflect on your day and savor another beautiful night in Italy.

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Day 11

Day 11

  • Lecce
  • Naples
  • More

Drive 452 km, 5 hours 17 min

  • Villa Comunale di Benevento
  • Arch of Trajan
  • La Dormiente del Sannio
  • Roman Theatre, Benevento
  • More

Dive into day 11 of your remarkable road trip in Italy. Today you'll explore 1 destination, including Benevento. At the end of the day, you’ll unwind at one of the finest accommodations in Naples, where you'll spend 1 night.

Catch Villa Comunale before the crowds roll in. This idyllic park is sure to ignite your curiosity. Next, dive into the photogenic features of Arch Of Trajan, a must-visit monument in the city.

In between sights, stop by local stores, picturesque photo spots, and small eateries. When you’re ready for your next attraction, proceed to La Dormiente Del Sannio, a worthwhile mountain range. For a change of scene, check out Roman Theatre, Benevento, known for its breathtaking features.

When you’re done exploring for the day, you’ll drive to your hotel in Naples. Check in and relax before you head out to tour the city.

Naples is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Naples.

Enjoy a delicious meal at Opera Restaurant, a top-rated dining destination in Naples. If you're in the mood to try something new, consider Trattoria San Ferdinando, another top spot with a mouthwatering menu. You might also want to secure a reservation at Anonymous Trattoria Gourmet. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Naples this evening.

After your delicious meal, get a taste of the vibrant nightlife with a visit to Gran Caffè Cimmino, known for its inviting atmosphere. Flanagan's Bar is another great option if you’re looking for a place to get the night started. Similarly, Bar Napoli provides a great setting to enjoy the night away.

Relax and look forward to more memorable moments to come!

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Day 12

Day 12

  • Naples - Departure day
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  • Via Toledo
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Day 12 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Naples before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

One of the best things to do on your last day is to explore Via Toledo, a street that you shouldn't miss while in Naples. Take your time to uncover its best sides and enjoy its proximity to many of the area’s best attractions.

Make the most of your final day in Italy by visiting Naples’s iconic markets and shopping establishments in the buzzing Via dei Mille. Secure the perfect souvenirs for your family and friends back home or buy yourself a remembrance of your amazing vacation. You can also browse through boutiques for stylish fashion choices. Elevate your style with pieces from high-end retail stores.

Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Naples.

If you're in the mood to try something new, consider Osteria Il Gobbetto, another top spot with a mouthwatering menu.

You’ll then say farewell to Naples. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!

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Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

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