12-Day Italy Self-Drive Road Trip With Itinerary from Naples traveling north to Viterbo, Florence, Siena, Rome, and Salerno

Day 2 of your road trip will take you to the best attractions Naples has to offer. Cherish the 1 night you have left in Naples by discovering the best things there are to see and do in the city.

Get ready to discover some of the most iconic wonders in Naples, including a church, a museum, and a cave system. Start your day at Chiesa Del Gesù Nuovo. This monumental church is an interesting place to see in Naples. Then, wander over to Cappella Sansevero. If photogenic sites excite you, this museum will be right up your alley. Nearby, you’ll also find Napoli Sotterranea Percorso Ufficiale. This standout cave system is a favorite among visitors.

Naples offers plenty to explore, ensuring every moment of your visit is filled with excitement and discovery. If you're up for more, Cattedrale Di Santa Maria Assunta is a locally renowned spot in the city that will captivate you with its unique charm.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

Indulge in a shopping spree at Naples's top shopping destination, Vomero! Enjoy the freedom to explore at your own pace, browsing unique boutique shops and discovering local treasures. Keep an eye out for artisan crafts, perfect for bringing a touch of Italy into your home. Beyond shopping, Vomero has plenty to offer, including cafes, essential services, seasonal events, and unique attractions for all ages.

As you explore more of Naples, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Prepare for an extraordinary culinary adventure in Naples by booking a table at Veritas, a 1-star Michelin restaurant that boasts an exceptional campanian and contemporary menu. For a different flavor experience, head to Il Comandante, renowned for its delectable creative and mediterranean dishes. This 1-star Michelin restaurant consistently wows guests, making it a memorable stop during your holiday. Looking for another option? Visit ARIA, a local gem known for its delightful contemporary and modern cuisine in Naples. Nestled in the city's heart, this 1-star Michelin restaurant is a perfect choice for discerning restaurant-goers seeking a new experience.

Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, Archivio Storico - Cocktail Bar & Wonderfood stands out as an excellent choice for a post-dinner cocktail. Alternatively, Archeobar offers an ideal atmosphere to enjoy the pleasures of the night. Babette Pub is also a great option that provides a perfect setting for a relaxing evening.

As the sun sets on another day of adventure, rest up and recharge for the next leg of your road trip in Italy.

On day 3 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 2 destinations, Naples and Tivoli. When you’re not sightseeing, take time to relax at your selected hotel in Viterbo, where you’ll be staying for 1 night.

Savor the day by visiting some of the best places to see in Naples, including a castle, a museum, and an archeological site. Start your adventure at Castel Nuovo. This captivating castle is a must-visit for travelers looking for a unique holiday experience. Make your way to Naples National Archaeological Museum located in Naples for an enchanting atmosphere.

Next, immerse yourself in the setting of Hadrian's Villa. Its picture-perfect features will captivate you.

When you’re done exploring for the day, you’ll drive to your hotel in Viterbo. Check in and spend some time relaxing before you head out to tour the city.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Viterbo. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Raise your glass and celebrate another amazing day of your road trip in Italy!

Experience an unparalleled adventure on day 4 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 vibrant destinations - Orvieto. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Florence. You will spend 2 nights here for some well-deserved relaxation.

Immerse yourself in Viterbo’s rich culture with today's sightseeing itinerary. Start your journey at Orvieto Cathedral. This enchanting church is sure to ignite your curiosity. Next, dive into the monumental features of Museo Dell'opera Del Duomo, a must-visit museum in the town.

In between sights, stop by local stores, picturesque photo spots, and small eateries. When you’re ready for your next attraction, proceed to Orvieto Underground, a curiosity-inducing cave system. For a change of scene, check out Well Of St. Patrick, known for its picture-perfect features.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Florence. Florence offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As dinnertime approaches, it's time to head out for a bite to eat in Florence. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Begin your culinary exploration in Florence by securing a reservation at Enoteca Pinchiorri. This renowned restaurant holds 3 Michelin star and offers an exceptional menu of italian contemporary cuisine. For another dining delight, visit Santa Elisabetta, celebrated for its delectable creative and mediterranean menu. This acclaimed 2-star Michelin-recipient consistently leaves guests satisfied, making it a must-visit during your holiday. Looking for a different experience? Discover Gucci Osteria da Massimo Bottura, a top local spot known for its tantalizing italian contemporary and international menu. With a 1-star Michelin recognition, it guarantees an exceptional dining adventure.

After your delicious meal, get a taste of the vibrant nightlife with a visit to Manifattura, known for its inviting atmosphere. Se·sto On Arno Rooftop Bar is another great option if you’re looking for a place to get the night started. Similarly, Il Vinile provides a great setting to enjoy the night away.

Relax and reminisce about your day in Italy and look forward to more memorable moments to come!

On day 5 of your road trip, you will have an entire day to explore Florence. You’ll stay in Florence for 1 night and discover all the best things to see and do in the area.

A top thing to do today is to explore Oltrarno, a must-see neighborhood in Florence. It's the perfect starting point for touring the top attractions in the area.

Discover a day packed with fun adventures, romantic experiences, and scenic views in Florence. Begin your sightseeing with Ponte Vecchio. This timeless historical landmark is one of the top attractions in the city. Proceed to Piazza Della Signoria, another must-visit attraction that enhances the city’s allure.

As you wander through the inviting streets of Florence, soak in the lively ambiance and take the opportunity to snap some photos. Next, head to Uffizi Gallery. This extraordinary art gallery is a traveler-favorite. Not far away, you’ll find Piazzale Michelangelo, another key site on your sightseeing itinerary.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

As dinnertime approaches, it's time to head out for a bite to eat in Florence. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Don’t miss out on dining at Ditta Artigianale, a top-rated dining destination in Florence. If you're in the mood to try something new, consider Trattoria Da Burde, another top spot with a mouthwatering menu. You might also want to secure a reservation at Casa Toscana. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Florence this evening.

Continue your evening by exploring the vibrant nightlife scene at Bar 50 Rosso, a prime destination for a thrilling night out. Also, don’t forget to check out Bitter Bar, a bar that offers unique local touches. Likewise, Archea Brewery provides an excellent alternative for a fun evening.

Raise your glass and celebrate another amazing day of your road trip in Italy!

Embark on another extraordinary experience on day 6 of your road trip in Italy. Today, you will make 2 stops and experience some of the highlights of Florence and Pisa. At the end of the day, you will enjoy the comforts of a top-rated hotel in Siena, which will be your home away from home for 1 night.

Bring your curiosity for today’s adventure around Florence. Some of the city’s most loved attractions await. Cathedral Of Santa Maria Del Fiore is the perfect place to start. This church is one of the most top-rated places to visit in Florence. Next, head to Galleria Dell'accademia, an interesting art gallery, known for its photogenic features.

In between the sights, don’t hesitate to take small detours to explore local stores and eateries. When you’re ready to continue your adventure, head to Leaning Tower Of Pisa. This masterful monument offers a unique experience that is highly recommended. Meanwhile, Piazza Del Duomo, Pisa adds its own distinct charm to your journey.

At the end of the day, you will drive to Siena, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

Indulge in a memorable dining experience at one of Siena's most popular restaurants, and connect with friendly locals for an authentic adventure.

Have a fantastic dining experience at Enoteca I Terzi, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Ristorante Tar-Tufo offers an enticing alternative with its varied menu. Additionally, Antica Trattoria Papei is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Siena.

Explore the vibrant nightlife at Meet Life Cafè after your meal, a hub for lively evenings and memorable moments. Or, head to Maudit Pub for a great selection of flavorful drinks and a charming setting. Furthermore, Bar Impero Siena is perfect for those looking to extend their night with a touch of local flavor.

As the sun sets on another day of adventure, rest up and recharge for the next leg of your road trip in Italy.

On day 7 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Vatican City. In the evening, you’ll end up in Rome, where you will stay for 3 nights.

Start your day at Sistine Chapel. Then, wander over to St. Peter's Basilica. Nearby, you’ll also find Saint Peter's Square.

Siena offers plenty to explore, ensuring every moment of your visit is filled with excitement and discovery. If you're up for more, Vatican Museums is an iconic spot in the city that will captivate you with its unique charm.

When you’re done exploring for the day, you’ll drive to your hotel in Rome. Check in and spend some time relaxing before you head out to tour the city.

As you explore more of Rome, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Get ready for an unforgettable culinary journey in Rome by reserving a table at La Pergola. Renowned as a 3-star Michelin restaurant, it offers an exceptional mediterranean and contemporary menu. For a different taste experience, head to Il Pagliaccio, recognized for its delicious creative and innovative dishes. This 2-star Michelin restaurant consistently impresses guests, ensuring a memorable addition to your holiday. Looking for another option? Make sure to visit Enoteca La Torre, a local favorite known for its delightful mediterranean and creative cuisine in Rome. Nestled in the heart of the city, this restaurant with 2 Michelin star is an ideal choice for discerning mediterranean and creative foodies seeking culinary excellence.

Continue your lively evening at La Botticella Of Poggi Giovanni, a perfect place for winding down or revving up the night, depending on which mood you’re in. Almalu Trastevere is another excellent bar that offers a great selection of drinks to suit any mood. If you prefer to go somewhere else, Bar Viminale Di Pepi Maurilio ensures a night out tailored to your taste.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in Italy.

Day 8 of your road trip across Italy promises a magnificent time exploring Rome. You have 2 nights left in Rome. Take the opportunity to experience more of the best attractions and activities in the city.

Trastevere is a fantastic place you can explore today in Rome. This neighborhood is a testament to the city’s character, and it's easy to spend hours just walking around and admiring the surroundings. Soak in the Rome-way-of-life and visit all the nearby sights. You should also check out Monti, a neighborhood offering more opportunities to enjoy the city’s vibrant atmosphere and landmarks.

Brace yourself for today’s incredible lineup of attractions in Rome, featuring fun adventures, scenic views, and picturesque spots. Start at Altare Della Patria, a notable monument in the city. Then, head to Roman Forum and soak in the ambiance of this historic archeological site.

There are many interesting places to see in Rome and when you are ready for more, go to Colosseum. This is one of the city’s most world-famous spots.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

Indulge in a memorable dining experience at one of Rome's most popular restaurants, and connect with friendly locals for an authentic adventure.

Make sure to reserve a table at RomAntica, an iconic dining spot in Rome. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Coso Ristorante, a popular restaurant in Rome. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of DEROMA - Farine Romane, a hidden gem nestled in Rome. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at Sant' Eustachio Caffè, a well-loved spot among locals and tourists. Or, head to Yellowsquare Rome. This bar boasts a welcoming environment that is perfect for winding down. You could also continue your night at Caffè Portofino, another top-rated place in the area.

Relax and recharge in preparation for another adventurous day in Italy!

Day 9 offers a multitude of experiences. You will stay in Rome for 1 night more, offering you enough time to explore at a relaxed pace.

One of the most iconic places you can visit today in Rome is Via del Corso. Allow yourself some time to explore this street and discover its unique quirks. You'll also find many of the best sightseeing spots nearby.

Start by visiting Castel Sant'angelo, a prime spot to begin your journey. This romantic castle is sure to impress. Next on your list is Piazza Navona, another must-visit landmark and globally renowned public square renowned for its enchanting features.

While exploring and sightseeing, take time to savor the ambiance of Rome by sampling some local delicacies or having a drink. When you’re ready for more sightseeing, head to Pantheon. This culturally significant monument is a remarkable attraction that offers a unique experience. Piazza Del Popolo also adds charm to your journey.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Rome. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Enjoy a delicious meal at Hotel de Russie, a top-rated dining destination in Rome. If you're in the mood to try something new, consider La Taverna Italiana, another top spot with a mouthwatering menu. You might also want to secure a reservation at The Parrot Bar. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Rome this evening.

After savoring a delicious meal, step into the vibrant nightlife at The Apartment Bar Roma, where the evening is just getting started. In the same way, Hotel Hassler Roma offers a unique charm perfect for experiencing the local bar scene in Rome.

Savor another day of unforgettable experiences in Italy!

Dive into day 10 of your remarkable road trip in Italy. Today you will explore Rome, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Salerno. You’ll stay here for 1 night.

Get ready for a day filled with family-friendly attractions, romantic experiences, and breathtaking views in the charming city of Rome. Your adventure starts at Trevi Fountain, a wondrous local hot spot. Another notable attraction to explore is Piazza Di Spagna. This iconic public square is known for its history-steeped appeal.

After soaking in the highlights of these sights, take some time to wander Rome's streets and immerse yourself in the local atmosphere. When you're ready to continue your sightseeing adventure, head to Spanish Steps. This history-steeped public square offers a fascinating experience that many visitors find memorable. Villa Borghese is also worth visiting.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Salerno. Salerno offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Salerno. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Start your culinary exploration in Salerno by securing a reservation at Re Maurì. This renowned restaurant holds 1 Michelin star and offers an exceptional menu of creative cuisine. Immerse yourself in the culinary delights of L'Unico Drink & Food Salerno, a popular restaurant in Salerno. With a menu designed to delight, it ensures a dining experience that transcends the ordinary.

Following your dinner, dive into the local bar culture at Hilton Bar E Gastronomia. Enjoy this evening's relaxed ambiance with delightful drinks. Alternatively, go to The Black Monday Speakeasy Tbm, the perfect place for those looking to experience the best of the nightlife. Similarly, Dòmo I' Vinaino Wine Bar - Enogastronomia provides excellent drinks and a great atmosphere, ensuring a memorable night out.

Raise your glass to another unforgettable day in Italy!

On day 11 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 3 destinations, Paestum, Amalfi, and Pompei. When you’re not sightseeing, take time to relax at your selected hotel in Naples, where you’ll be staying for 1 night.

Today’s route brings family-friendly attractions, breathtaking views, and photo-friendly spots. The first attraction of today is Archaeological Park Of Paestum. This locally renowned archeological site is a historic place to see in Salerno.

As you stroll around Salerno, take in the distinct atmosphere and learn what makes this hamlet so unique. Maximize your sightseeing with a visit to Archaeological Park Of Pompeii. This locally renowned archeological site offers a historic encounter with Salerno. Next, make your way to Teatro Grande to add another highlight to your day. Whether you decide to get entrance tickets for all attractions or you prefer admiring from a distance, amazing experiences await on this day in Salerno.

At the end of the day, you will drive to Naples, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a day of adventure, treat yourself to an exquisite dinner at one of Naples's best restaurants.

Don’t miss out on dining at Opera Restaurant, a top-rated dining destination in Naples. If you're in the mood to try something new, consider Trattoria San Ferdinando, another top spot with a mouthwatering menu. You might also want to secure a reservation at Anonymous Trattoria Gourmet. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Naples this evening.

After enjoying a fulfilling meal, continue your evening at Gran Caffè Cimmino, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, Flanagan's Bar offers a welcoming atmosphere for easing into the nightlife. Similarly, Bar Napoli provides an excellent environment for a relaxed and enjoyable evening.

Take some time to reflect on your day and savor another beautiful night in Italy.