12-Day Italy Self-Drive Road Trip With Itinerary from Naples traveling west to Viterbo, Florence, Arezzo, and Rome

Day 2 of your road trip will take you to the best attractions Naples has to offer. Cherish the 2 nights you have left in Naples by discovering the best things there are to see and do in the city.

Get ready for a day filled with a picture-perfect, a history-steeped, a remarkable, a mesmerizing, a monumental, a culturally significant, and a romantic in the charming city of Naples. Your adventure starts at Naples National Archaeological Museum, an interesting local hot spot. Another notable attraction to explore is Cappella Sansevero. This well-known museum is known for its photogenic appeal.

After soaking in the highlights of these sights, take some time to wander Naples's streets and immerse yourself in the local atmosphere. When you're ready to continue your sightseeing adventure, head to Napoli Sotterranea Percorso Ufficiale. This heritage-rich cave system offers a fascinating experience that many visitors find memorable. Cattedrale Di Santa Maria Assunta is also worth visiting, along with Piazza Del Plebiscito. These standout landmarks offer unique experiences that add to the day’s enjoyment.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

After a day of adventure, treat yourself to an exquisite dinner at one of Naples's best restaurants.

Get ready for an unforgettable culinary journey in Naples by reserving a table at Veritas. Renowned as a 1-star Michelin restaurant, it offers an exceptional campanian and contemporary menu. For a different taste experience, head to Il Comandante, recognized for its delicious creative and mediterranean dishes. This 1-star Michelin restaurant consistently impresses guests, ensuring a memorable addition to your holiday. Looking for another option? Make sure to visit ARIA, a local favorite known for its delightful contemporary and modern cuisine in Naples. Nestled in the heart of the city, this restaurant with 1 Michelin star is an ideal choice for discerning contemporary and modern foodies seeking culinary excellence.

After your meal, keep the night alive at a bar like Archivio Storico - Cocktail Bar & Wonderfood, known for its lively atmosphere. Archeobar is another top recommendation that provides the perfect setting with well-crafted drinks and a welcoming ambiance. Similarly, Babette Pub offers an excellent atmosphere for those looking to amp up the evening.

Relax and recharge in preparation for another adventurous day in Italy!

On day 3 of your road trip, you will have an entire day to explore Naples. You’ll stay in Naples for 1 night and discover all the best things to see and do in the area.

Today, you'll explore some of the most beautiful places in Naples, including a castle, a church, and a monument. Start your day with a visit to Castel Sant'elmo. This locally renowned castle is a must-visit in the city. When you’re ready for your next discovery, continue to Chiesa Del Gesù Nuovo, which may be one of the most photogenic places you will experience today.

One of the best things about exploring Naples on a self-guided tour is that you set the pace. There’s plenty of time for detours and discovering hidden gems. When you’re ready for your next stop, make your way to Complesso Monumentale Di Santa Chiara, one of the city’s most locally appreciated monument. If you’re up for more discoveries, don’t forget to reserve some time for Castel Nuovo.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

As you explore more of Naples, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Enjoy a delicious meal at Opera Restaurant, a highly-rated dining destination in Naples. If you're eager to try something different, consider Trattoria San Ferdinando, another top spot with a tantalizing menu. You might also want to secure a reservation at Anonymous Trattoria Gourmet. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Naples this evening.

Continue your lively evening at Gran Caffè Cimmino, a perfect place for winding down or revving up the night, depending on which mood you’re in. Flanagan's Bar is another excellent bar that offers a great selection of drinks to suit any mood. If you prefer to go somewhere else, Bar Napoli ensures a night out tailored to your taste.

As the sun sets on another day of adventure, rest up and recharge for the next leg of your road trip in Italy.

Dive into day 4 of your remarkable road trip in Italy. Today you will explore Naples and Tivoli, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Viterbo. You’ll stay here for 1 night.

Enjoy the perfect balance of relaxation and exploration in Naples today. One of the most intriguing attractions included on the itinerary is Royal Palace Of Naples. This culturally significant palace will help you start your sightseeing on top. Then, take a leisurely stroll to San Carlo Theatre and learn what makes this historic opera house unique.

Throughout the day, make sure to take breaks to appreciate the surroundings.

When you’re ready to jump back into the car and say goodbye to Naples, you’ll hit the road in the direction of Tivoli. This drive usually takes around 2 hours 23 min. When you arrive, enjoy some sightseeing.

Begin your journey at Villa D'este and explore the enchanting features.

After soaking up all the sights of today's itinerary, you'll be ready to hit the road in the direction of your accommodation in Viterbo. Viterbo offers plenty of top-rated hotels and other places to stay on any travel budget. Take some time to relax before you head out to explore.

Indulge in a memorable dining experience at one of Viterbo's most popular restaurants, and connect with friendly locals for an authentic adventure.

Relax and reminisce about your day in Italy and look forward to more memorable moments to come!

On day 5 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Siena. In the evening, you’ll end up in Florence, where you will stay for 2 nights.

Fasten your seatbelt and make your way to your next stop. Siena, home to many well-known sights in the region, is a lovely destination on today’s itinerary. Keep in mind that your travel time from Viterbo to Siena may take around 2 hours 4 min without traffic disruptions. Upon arrival in Siena, we highly recommend checking out some of the top attractions.

Piazza Del Campo is a spectacular public square we recommend making time to visit today. Discover its UNESCO world heritage-designated features before continuing your self-guided tour to Pubblico Palace, a respected palace that’s well-regarded in the area. Next, stop by Siena Cathedral, a history-steeped church. While you’re nearby, don’t forget to visit Fortezza Medicea (siena), a picture-perfect and truly unique monument.

When you’re done exploring for the day, you’ll drive to your hotel in Florence. Check in and spend some time relaxing before you head out to tour the city.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Florence. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Treat yourself to an extraordinary dining experience at Enoteca Pinchiorri, a 3-star Michelin restaurant offering an incredible italian contemporary menu. Alternatively, if your taste buds call for something different, Santa Elisabetta is one of the best restaurants for creative and mediterranean cuisine in Florence. This 2-star Michelin-awardee earns consistently high praises from guests. We also recommend checking out the menu at Gucci Osteria da Massimo Bottura. As a top-rated establishment with 1 Michelin star, it is an ideal choice for italian contemporary and international cuisine in the city.

After your delicious meal, get a taste of the vibrant nightlife with a visit to Manifattura, known for its inviting atmosphere. Se·sto On Arno Rooftop Bar is another great option if you’re looking for a place to get the night started. Similarly, Il Vinile provides a great setting to enjoy the night away.

Raise your glass to another unforgettable day in Italy!

Day 6 offers a multitude of experiences. You will stay in Florence for 1 night more, offering you enough time to explore at a relaxed pace.

Prepare for a day full of a romantic, an enchanting, an eye-catching, a heritage-rich, a majestic, a sacred, and a noteworthy. When you’re ready, kick off your sightseeing adventure at Piazzale Michelangelo. This spectacular observation deck is a must-visit for anyone seeking a unique vacation experience. Another sight you shouldn’t miss is Basilica Of Santa Croce In Florence, one of the city’s most promising highlights.

Next, check out Piazza Della Signoria, one of the most famous places to see in Florence. This public square is a favorite among locals and travelers alike. Enjoy some downtime and refreshments before continuing to your next stop, Uffizi Gallery. Wander around and soak in the historic atmosphere this art gallery offers. Finally, take the path to the iconic Ponte Vecchio, the last of our attraction recommendations for today.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

As dinnertime approaches, it's time to head out for a bite to eat in Florence. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Don’t miss out on dining at Ditta Artigianale, a top-rated dining destination in Florence. If you're in the mood to try something new, consider Trattoria Da Burde, another top spot with a mouthwatering menu. You might also want to secure a reservation at Casa Toscana. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Florence this evening.

After your delicious meal, get a taste of the vibrant nightlife with a visit to Bar 50 Rosso, known for its inviting atmosphere. Bitter Bar is another great option if you’re looking for a place to get the night started. Similarly, Archea Brewery provides a great setting to enjoy the night away.

Take some time to reflect on your day and savor another beautiful night in Italy.

Experience an unparalleled adventure on day 7 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 2 vibrant destinations - Florence and Pisa. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Arezzo. You will spend 1 night here for some well-deserved relaxation.

Today, you'll explore some of the most beautiful places in Florence, including a church and a food market. Start your day with a visit to Cathedral Of Santa Maria Del Fiore. This top-rated church is a must-visit in the city. When you’re ready for your next discovery, continue to Central Market, which may be one of the most visually striking places you will experience today.

Set your GPS to Pisa and hit the road. Expect a journey of approximately 1 hour 18 min without stops. Soak in the beautiful landscapes as you drive and look forward to exploring your next destination. Pisa beckons with new experiences!

One of our top recommendations for your sightseeing is Leaning Tower Of Pisa. Spend some time admiring the breathtaking features of the monument before you continue to your next stop. Then, head to Piazza Del Duomo, Pisa. This world-famous public square is a traveler-favorite in the city. Not far away, you’ll also find Campo Santo. Feed your curiosity by learning something new about the cemetery.

At the end of the day, you will drive to Arezzo, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you explore more of Arezzo, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Have a memorable dining experience in Arezzo by booking a table at Octavin, renowned as a 1-star Michelin restaurant presenting an exceptional creative menu. Immerse yourself in the culinary delights of La Clandestina, a popular restaurant in Arezzo. With a menu designed to delight, it ensures a dining experience that transcends the ordinary.

Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, Liquid Bar stands out as an excellent choice for a post-dinner cocktail.

Get a good night's sleep and look forward to another great day on the road in Italy!

Embark on another extraordinary experience on day 8 of your road trip in Italy. Today, you will make 1 stop and experience some of the highlights of Vatican City. At the end of the day, you will enjoy the comforts of a top-rated hotel in Rome, which will be your home away from home for 3 nights.

When you’re ready to jump back into the car and say goodbye to Arezzo, you’ll hit the road in the direction of Vatican City, Vatican City. Witness the landscapes transform as you cross the border to Vatican City. This drive usually takes around 2 hours 32 min. When you arrive, enjoy some sightseeing.

One of our top recommendations for your sightseeing is Vatican Museums. Then, head to Sistine Chapel. This impressive chapel is a traveler-favorite in the city. Not far away, you’ll also find Saint Peter's Square. Feed your curiosity by learning something new about the square. Next, continue your journey to St. Peter's Basilica, a globally renowned major basilica.

After soaking up all the sights of today's itinerary, you'll be ready to hit the road in the direction of your accommodation in Rome. Rome offers plenty of top-rated hotels and other places to stay on any travel budget. Take some time to relax before you head out to explore.

After a day of adventure, treat yourself to an exquisite dinner at one of Rome's best restaurants.

Experience a symphony of flavors at La Pergola in Rome by securing a reservation in advance. Renowned for its 3-star Michelin distinction, La Pergola delights its guests with its exceptional variety of meals showcasing delicious mediterranean and contemporary cuisine. For a palate-pleasing alternative, make sure to dine at Il Pagliaccio, acclaimed for its delectable creative and innovative specialties. This local 2-star Michelin establishment consistently satisfies guests, ensuring an unforgettable holiday experience. Want to go on another culinary journey? Delight your senses at Enoteca La Torre, a top-rated restaurant known for its outstanding menu. Known as a top-rated 2-star Michelin establishment, it's a top choice for mediterranean and creative cuisine in the city.

After enjoying a fulfilling meal, continue your evening at La Botticella Of Poggi Giovanni, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, Almalu Trastevere offers a welcoming atmosphere for easing into the nightlife. Similarly, Bar Viminale Di Pepi Maurilio provides an excellent environment for a relaxed and enjoyable evening.

Take some time to reflect on your day and savor another beautiful night in Italy.

Day 9 of your road trip across Italy promises a magnificent time exploring Rome. You have 2 nights left in Rome. Take the opportunity to experience more of the best attractions and activities in the city.

Savor the day by visiting some of the best places to see in Rome, including a public square, an archeological site, and a monument. Start your adventure at Piazza Navona. This timeless public square is a must-visit for travelers looking for a unique holiday experience. Make your way to Campo De' Fiori located in Rome for an enchanting atmosphere.

Next, immerse yourself in the setting of Roman Forum. Its breathtaking features will captivate you. After the archeological site, continue your tour of the city with a visit to Colosseum. This archeological site has an UNESCO world heritage-listed appeal. For a change of pace, head to Circus Maximus. As one of the most captivating attractions in Rome, this archeological site is an excellent place to end your self-guided tour.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

Indulge in a memorable dining experience at one of Rome's most popular restaurants, and connect with friendly locals for an authentic adventure.

Make sure to reserve a table at RomAntica, an iconic dining spot in Rome. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Coso Ristorante, a popular restaurant in Rome. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of DEROMA - Farine Romane, a hidden gem nestled in Rome. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Explore the vibrant nightlife at Sant' Eustachio Caffè after your meal, a hub for lively evenings and memorable moments. Or, head to Yellowsquare Rome for a great selection of flavorful drinks and a charming setting. Furthermore, Caffè Portofino is perfect for those looking to extend their night with a touch of local flavor.

Relax and reminisce about your day in Italy and look forward to more memorable moments to come!

Day 10 of your road trip will take you to the best attractions Rome has to offer. Cherish the 1 night you have left in Rome by discovering the best things there are to see and do in the city.

Get ready to discover some of the most iconic wonders in Rome, including a castle, a public square, and a park. Start your day at Castel Sant'angelo. This enchanting castle is a widely recognized place to see in Rome. Then, wander over to Piazza Di Spagna. If visually striking sites excite you, this public square will be right up your alley. Nearby, you’ll also find Spanish Steps. This enchanting public square is a favorite among visitors.

Rome offers plenty to explore, ensuring every moment of your visit is filled with excitement and discovery. If you're up for more, Piazza Del Popolo is a spectacular spot in the city that will captivate you with its unique charm. When you’re done at the public square, don’t forget to check out the romantic Villa Borghese. Take a moment to appreciate the fascinating details of this famous park in Rome.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Rome. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Treat yourself to a delightful dinner at Hotel de Russie, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try La Taverna Italiana? It's another excellent option with a diverse menu. Consider reserving a table at The Parrot Bar as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Rome.

Following your dinner, dive into the local bar culture at The Apartment Bar Roma. Enjoy this evening's relaxed ambiance with delightful drinks. Alternatively, go to Hotel Hassler Roma, the perfect place for those looking to experience the best of the nightlife.

Get a good night's sleep and look forward to another great day on the road in Italy!

On day 11 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, Rome. When you’re not sightseeing, take time to relax at your selected hotel in Naples, where you’ll be staying for 1 night.

Prepare for a day full of a breathtaking, an instagrammable, a history-steeped, a majestic, a noteworthy, a stunning, and an UNESCO world heritage-designated. When you’re ready, kick off your sightseeing adventure at Altare Della Patria. This captivating monument is a must-visit for anyone seeking a unique vacation experience. Another sight you shouldn’t miss is Largo Di Torre Argentina, one of the city’s most promising highlights.

Next, check out Pantheon, one of the most timeless places to see in Rome. This monument is a favorite among locals and travelers alike. Enjoy some downtime and refreshments before continuing to your next stop, Basilica Di Santa Maria Maggiore. Wander around and soak in the photogenic atmosphere this church offers.

When you’re done exploring for the day, you’ll drive to your hotel in Naples. Check in and spend some time relaxing before you head out to tour the city.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Naples. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Treat yourself to a wonderful meal at Piazza Sannazaro, a top-rated dining spot in Naples. If you're in the mood for something new, try Osteria Il Gobbetto, another premier location with a delectable menu. You might also want to book a table at Trattoria Castel Nuovo. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Naples.

Let the evening flow smoothly from dinner to drinks at Parthenope Bar, a top-rated bar in the area. For other recommendations, Gran Caffè Mexico provides a perfect setting for rounding out your night with style and great drinks. Likewise, Novecento Wine Bar offers a memorable night with diverse drink options and excellent service.

Raise your glass and celebrate another amazing day of your road trip in Italy!