12-Day Italy Self-Drive Road Trip With Itinerary from Naples traveling west to Viterbo, Florence, and Rome
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Explore the best of Italy on a 12-day road trip! Uncover hidden gems and experience the rich culture firsthand as you journey through Naples, Tivoli, Viterbo, Florence, Arezzo, and Rome. This road trip itinerary in Italy seamlessly combines exploration with relaxation.
This perfectly planned road trip itinerary in Italy takes you through some of the best places to see in the country. You will spend 4 nights in Naples, 1 night in Viterbo, 4 nights in Florence, and 2 nights in Rome. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!
With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.
Upon arriving in Naples, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.
An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Trevi Fountain and Colosseum are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Pantheon, learn more about the unique Piazza Navona, and immerse yourself in the vibrant atmosphere of Ponte Vecchio.
As you hit the open road and drive through Naples, Tivoli, Viterbo, Florence, Arezzo, and Rome, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.
Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.
This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.
The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!
Itinerary summary
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Day 1
- Naples - Arrival day
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- piazza del Plebiscito
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Welcome to Naples, the perfect starting point for your road trip in Italy! Pick up your rental car and let the adventure begin. You will spend 3 nights immersing yourself in Naples's charm before embarking on the next leg of your journey.
Naples is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Piazza Del Plebiscito, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.
Make your way to your chosen hotel. Check-in typically starts between 2 and 4 PM in Naples. Make yourself at home and enjoy some downtime before heading out again.
As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Naples, it's often a good idea to reserve a table in advance.
Don’t miss out on dining at L'Oca Nera Irish Pub, a top-rated dining destination in Naples. If you're in the mood to try something new, consider Mimì alla Ferrovia, another top spot with a mouthwatering menu. You might also want to secure a reservation at Spuzzulè Winebar. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Naples this evening.
After enjoying a fulfilling meal, continue your evening at Happening Cocktail Bar, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, Shanti Art Musik Bar offers a welcoming atmosphere for easing into the nightlife. Similarly, Gran Caffè Gambrinus provides an excellent environment for a relaxed and enjoyable evening.
Raise a toast to the start of your 12-day road trip in Italy!
Day 2
- Naples
- More
Drive 7 km, 41 min
- Cattedrale di Santa Maria Assunta
- Napoli Sotterranea Percorso Ufficiale
- Cappella Sansevero
- Naples National Archaeological Museum
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Day 2 offers a multitude of experiences. You will stay in Naples for 2 nights more, offering you enough time to explore at a relaxed pace.
Enjoy the perfect balance of relaxation and exploration in Naples today. One of the most captivating attractions included on the itinerary is Cattedrale Di Santa Maria Assunta. This symbolic church will help you start your sightseeing on top. Then, take a leisurely stroll to Napoli Sotterranea Percorso Ufficiale and learn what makes this heritage-rich cave system unique.
Throughout the day, make sure to take breaks to appreciate the surroundings. Next up, visit the captivating Cappella Sansevero. After exploring the museum, head to Naples National Archaeological Museum. This captivating museum is a highlight in Naples.
Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.
As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Naples. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.
Discover the culinary delights of Naples by securing a reservation at Veritas. Esteemed for its 1-star Guide Michelin recognition, this restaurant offers a remarkable selection of campanian and contemporary cuisine. For an alternative dining experience, try Il Comandante, renowned for its delicious creative and mediterranean dishes. This esteemed 1-star Michelin-recipient consistently impresses guests, making it a must-visit spot during your holiday. Craving more culinary excitement? Head to ARIA, a highly recommended local eatery celebrated for its mouthwatering contemporary and modern menu. With its 1-star Michelin recognition, it offers an unforgettable dining adventure.
Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, Archivio Storico - Cocktail Bar & Wonderfood stands out as an excellent choice for a post-dinner cocktail. Alternatively, Archeobar offers an ideal atmosphere to enjoy the pleasures of the night. Babette Pub is also a great option that provides a perfect setting for a relaxing evening.
Celebrate another amazing day of your road trip adventure in Italy!
Day 3
- Naples
- More
Drive 7 km, 1 hour 29 min
- Castel Sant'Elmo
- Chiesa del Gesù Nuovo
- Palazzo Mannajuolo
- Chiaia
- Quartiere Spagnolo
- More
On day 3 of your road trip, you will have an entire day to explore Naples. You’ll stay in Naples for 1 night and discover all the best things to see and do in the area.
At the top of the list of things to do today is to explore Chiaia, a neighborhood that captures the true essence of Naples. Take your time to uncover its best sides and enjoy its proximity to many of the area’s best attractions. Another must-visit is Quartiere Spagnolo, a neighborhood offering a different perspective on Naples.
A blend of fun adventures, scenic views, and picturesque spots await you in Naples on today’s itinerary. First up is the captivating castle, Castel Sant'elmo. Afterward, continue to Chiesa Del Gesù Nuovo, a church every traveler should visit.
As you explore Naples’s charming streets, take in the lively atmosphere and get to know the character of the city. Next, make your way to Palazzo Mannajuolo. This intriguing palace is an essential stop.
Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.
Visit Via dei Mille in Naples for an unforgettable shopping experience. Browse unique boutiques and luxurious stores, each offering delightful surprises. Find unique souvenirs or items to take home. After shopping, explore what Via dei Mille has to offer, including attractions, essential services, and vibrant community activities.
As dinnertime approaches, it's time to head out for a bite to eat in Naples. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.
Dine in style at Opera Restaurant, a top recommendation for dinner tonight. Or, for a change of pace, Trattoria San Ferdinando boasts a menu that's sure to impress. Also, be sure to check out Anonymous Trattoria Gourmet. Known as a local hotspot, it’s a great choice for tonight in Naples.
After your meal, keep the night alive at a bar like Gran Caffè Cimmino, known for its lively atmosphere. Flanagan's Bar is another top recommendation that provides the perfect setting with well-crafted drinks and a welcoming ambiance. Similarly, Bar Napoli offers an excellent atmosphere for those looking to amp up the evening.
Say good night to Naples and look forward to another great day of your road trip in Italy!
Day 4
- Naples
- Viterbo
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Drive 318 km, 3 hours 42 min
- Castel Nuovo
- Hadrian's Villa
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Dive into day 4 of your remarkable road trip in Italy. Today you will explore Naples and Tivoli, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Viterbo. You’ll stay here for 1 night.
Enjoy the perfect balance of relaxation and exploration in Naples today. One of the most locally renowned attractions included on the itinerary is Castel Nuovo. This historic castle will help you start your sightseeing on top. Then, take a leisurely stroll to Hadrian's Villa and learn what makes this UNESCO world heritage-designated archeological site unique.
Throughout the day, make sure to take breaks to appreciate the surroundings.
After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Viterbo. Viterbo offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.
As you explore more of Viterbo, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.
Celebrate another amazing day of your road trip adventure in Italy!
Day 5
- Viterbo
- Florence
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Drive 217 km, 2 hours 51 min
- Piazza del Plebiscito
- Palazzo dei Papi di Viterbo
- Centro storico medievale - Viterbo
- Terme dei papi
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Embark on another extraordinary experience on day 5 of your road trip in Italy. Today, you will make 1 stop and experience some of the highlights of Viterbo. At the end of the day, you will enjoy the comforts of a top-rated hotel in Florence, which will be your home away from home for 4 nights.
A blend of family-friendly attractions, romantic experiences, and photo-friendly spots await you in Viterbo on today’s itinerary. First up is the underrated public square, Piazza Del Plebiscito. Afterward, continue to Palazzo Dei Papi Di Viterbo, a palace every traveler should visit.
As you explore Viterbo’s charming streets, take in the lively atmosphere and get to know the character of the city. Next, make your way to Centro Storico Medievale - Viterbo. This frequently visited historical landmark is an essential stop. Following that, head to Terme Dei Papi, another must-visit site that will enhance your experience.
At the end of the day, you will drive to Florence, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.
After a day of adventure, treat yourself to an exquisite dinner at one of Florence's best restaurants.
Discover the culinary delights of Florence by securing a reservation at Enoteca Pinchiorri. Esteemed for its 3-star Guide Michelin recognition, this restaurant offers a remarkable selection of italian contemporary cuisine. For an alternative dining experience, try Santa Elisabetta, renowned for its delicious creative and mediterranean dishes. This esteemed 2-star Michelin-recipient consistently impresses guests, making it a must-visit spot during your holiday. Craving more culinary excitement? Head to Gucci Osteria da Massimo Bottura, a highly recommended local eatery celebrated for its mouthwatering italian contemporary and international menu. With its 1-star Michelin recognition, it offers an unforgettable dining adventure.
After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at Manifattura, a well-loved spot among locals and tourists. Or, head to Se·sto On Arno Rooftop Bar. This bar boasts a welcoming environment that is perfect for winding down. You could also continue your night at Il Vinile, another top-rated place in the area.
Raise your glass and celebrate another amazing day of your road trip in Italy!
Day 6
- Florence
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Drive 14 km, 50 min
- Parco delle Cascine
- piazza della Signoria
- Palazzo Vecchio
- Uffizi Gallery
- Ponte Vecchio
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Day 6 of your road trip across Italy promises a magnificent time exploring Florence. You have 3 nights left in Florence. Take the opportunity to experience more of the best attractions and activities in the city.
Today’s well-planned self-sightseeing route offers several fun adventures, romantic experiences, and natural wonders. Whether you decide to explore Florence on foot, use public transport, or join a guided tour, there are a few attractions you don’t want to miss. Parco Delle Cascine is the first of them. Spend some time admiring this serene park before continuing your journey. Piazza Della Signoria is your next stop. This famous public square is one of the best-rated sights in Florence.
Consider grabbing some lunch or a light snack to keep your energy going. Beyond the above-mentioned attractions, today is also the perfect time to visit Palazzo Vecchio. This romantic palace is a sight to behold. To round off your sightseeing experience, visit Uffizi Gallery and Ponte Vecchio.
Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.
After a day of adventure, treat yourself to an exquisite dinner at one of Florence's best restaurants.
Make sure to reserve a table at Ditta Artigianale, an iconic dining spot in Florence. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Trattoria Da Burde, a popular restaurant in Florence. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Casa Toscana, a hidden gem nestled in Florence. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.
Explore the vibrant nightlife at Bar 50 Rosso after your meal, a hub for lively evenings and memorable moments. Or, head to Bitter Bar for a great selection of flavorful drinks and a charming setting. Furthermore, Archea Brewery is perfect for those looking to extend their night with a touch of local flavor.
Head back to your accommodation in Florence and get some rest in preparation for another magical day of your road trip in Italy!
Day 7
- Florence
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Drive 2 km, 37 min
- Giotto's Bell Tower
- Cathedral of Santa Maria del Fiore
- Brunelleschi's dome
- Central Market
- Basilica of Santa Maria Novella
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Day 7 of your road trip will take you to the best attractions Florence has to offer. Cherish the 2 nights you have left in Florence by discovering the best things there are to see and do in the city.
Bring your curiosity for today’s adventure around Florence. Some of the city’s most loved attractions await. Giotto's Bell Tower is the perfect place to start. This monument is one of the most worthwhile places to visit in Florence. Next, head to Cathedral Of Santa Maria Del Fiore, an astonishing church, known for its history-steeped features.
In between the sights, don’t hesitate to take small detours to explore local stores and eateries. When you’re ready to continue your adventure, head to Brunelleschi's Dome. This culturally significant monument offers a unique experience that is highly recommended. Meanwhile, Central Market adds its own distinct charm to your journey. Finish your day with a visit to Basilica Di Santa Maria Novella, Firenze (fi), a history-steeped church in Florence.
Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.
After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Florence. Enjoy a satisfying meal that will recharge you for tonight's adventures.
Treat yourself to a delicious dinner at Ristorante Buca Mario, an excellent option for tonight's dining. Looking for something different? Agricola Toscana offers a tantalizing alternative with its diverse menu. And don’t miss Eataly Firenze. With its reputation for pleasing customers, it’s a fantastic choice for tonight in Florence.
To truly maximize your evening out, consider visiting Gosh* after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to Antico Caffè Del Moro - Art Bar Firenze, another bar with an inviting ambiance. Similarly, Quelo Bar also offers a great atmosphere, ensuring a night filled with enjoyment and relaxation.
As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in Italy.
Day 8
- Florence
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Drive 11 km, 1 hour 17 min
- David
- Galleria dell'Accademia
- Palazzo Pitti
- The Boboli Gardens
- Oltrarno
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Day 8 offers a multitude of experiences. You will stay in Florence for 1 night more, offering you enough time to explore at a relaxed pace.
Set aside time today to explore Oltrarno, a standout neighborhood that reflects the essence of the city. While you're there, you'll also be within reach of some of the city's top landmarks, making it easy to maximize your day.
Today’s route brings fun adventures, photo-friendly spots, and historic treasures. The first attraction of today is David. Continue your discovery at Galleria Dell'accademia, a detailed art gallery with stories to tell.
As you stroll around Florence, take in the distinct atmosphere and learn what makes this city so unique. Maximize your sightseeing with a visit to Pitti Palace. This interesting palace offers a respected encounter with Florence. Next, make your way to The Boboli Gardens to add another highlight to your day. Whether you decide to get entrance tickets for all attractions or you prefer admiring from a distance, amazing experiences await on this day in Florence.
Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.
Indulge in a memorable dining experience at one of Florence's most popular restaurants, and connect with friendly locals for an authentic adventure.
Treat yourself to a wonderful meal at Tijuana, a top-rated dining spot in Florence. If you're in the mood for something new, try Djària - American Bar, another premier location with a delectable menu. You might also want to book a table at The Florence Irish Pub. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Florence.
As the sun sets on another day of adventure, rest up and recharge for the next leg of your road trip in Italy.
Day 9
- Florence
- Rome
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Drive 309 km, 4 hours 13 min
- Basilica of Santa Croce in Florence
- piazzale Michelangelo
- piazza Grande
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On day 9 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Florence and Arezzo. In the evening, you’ll end up in Rome, where you will stay for 2 nights.
Today’s route brings family-friendly attractions, photo-friendly spots, and history-rich sites. The first attraction of today is Basilica Of Santa Croce In Florence. This notable church is a culturally significant place to see in Florence. Continue your discovery at Piazzale Michelangelo, a romantic observation deck with stories to tell.
As you stroll around Florence, take in the distinct atmosphere and learn what makes this city so unique. Maximize your sightseeing with a visit to Piazza Grande. This well-known public square offers a romantic encounter with Florence. Whether you decide to get entrance tickets for all attractions or you prefer admiring from a distance, amazing experiences await on this day in Florence.
When you’re done exploring for the day, you’ll drive to your hotel in Rome. Check in and spend some time relaxing before you head out to tour the city.
As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Rome. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.
Start your culinary exploration in Rome by securing a reservation at La Pergola. This renowned restaurant holds 3 Michelin star and offers an exceptional menu of mediterranean and contemporary cuisine. For another dining delight, visit Il Pagliaccio, celebrated for its delectable creative and innovative menu. This acclaimed 2-star Michelin-recipient consistently leaves guests satisfied, making it a must-visit during your holiday. Looking for a different experience? Discover Enoteca La Torre, a top local spot known for its tantalizing mediterranean and creative menu. With a 2-star Michelin recognition, it guarantees an exceptional dining adventure.
Keep the excitement of the evening going by visiting a bar or two. La Botticella Of Poggi Giovanni is an excellent place to start. You could also check out Almalu Trastevere, offering a different kind of charm. A last recommendation for the day is Bar Viminale Di Pepi Maurilio. This bar promises an enjoyable experience with tasty drinks and a vibrant setting.
Raise your glass to another unforgettable day in Italy!
Day 10
- Rome
- More
Drive 6 km, 51 min
- Piazza Navona
- Piazza di Spagna
- Trastevere
- Via del Corso
- Via dei Condotti
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On day 10 of your road trip, you will have an entire day to explore Rome. You’ll stay in Rome for 1 night and discover all the best things to see and do in the area.
Trastevere is a neighborhood that stands out as one of the must-see places in Rome. Take a moment to explore its distinct atmosphere, and don’t miss the popular sightseeing spots just a short walk away. For another highlight, head to Via del Corso, a street offering its own unique experiences.
Begin your adventure at Piazza Navona. This is a timeless public square you should not miss. Another must-see is Piazza Di Spagna, a wondrous public square in Rome.
Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.
As you explore more of Rome, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.
Enjoy a delicious meal at RomAntica, a top-rated dining destination in Rome. If you're in the mood to try something new, consider Coso Ristorante, another top spot with a mouthwatering menu. You might also want to secure a reservation at DEROMA - Farine Romane. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Rome this evening.
Keep the excitement of the evening going by visiting a bar or two. Sant' Eustachio Caffè is an excellent place to start. You could also check out Yellowsquare Rome, offering a different kind of charm. A last recommendation for the day is Caffè Portofino. This bar promises an enjoyable experience with tasty drinks and a vibrant setting.
Relax and recharge in preparation for another adventurous day in Italy!
Day 11
- Rome
- Naples
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Drive 232 km, 3 hours 22 min
- Pantheon
- Trevi Fountain
- Roman Forum
- Colosseum
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On day 11 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, Rome. When you’re not sightseeing, take time to relax at your selected hotel in Naples, where you’ll be staying for 1 night.
Today's adventure in Rome promises more breathtaking discoveries and enriching experiences! Begin at Pantheon. This instagrammable monument is a highlight of any visit in the city. Then, enjoy Trevi Fountain, another history-steeped attraction that never fails to captivate visitors. Next, head over to Roman Forum, one of the city’s most globally renowned attractions, known for its picture-perfect features.
If you’re looking for more, spend time soaking in the atmosphere of Colosseum. This UNESCO world heritage-listed archeological site is frequented by locals and tourists alike. To complete your memorable day, make sure to take a stroll around the area.
After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Naples. Naples offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.
Indulge in a memorable dining experience at one of Naples's most popular restaurants, and connect with friendly locals for an authentic adventure.
Treat yourself to a delightful dinner at Piazza Sannazaro, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Osteria Il Gobbetto? It's another excellent option with a diverse menu. Consider reserving a table at Trattoria Castel Nuovo as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Naples.
Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, Parthenope Bar stands out as an excellent choice for a post-dinner cocktail. Alternatively, Gran Caffè Mexico offers an ideal atmosphere to enjoy the pleasures of the night. Novecento Wine Bar is also a great option that provides a perfect setting for a relaxing evening.
Take some time to reflect on your day and savor another beautiful night in Italy.
Day 12
- Naples - Departure day
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- Ovo Castle
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Day 12 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Naples before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.
If you're up for some more sightseeing, begin at Ovo Castle. This well-known castle is a popular place to see in the city.
As your final day in Italy unfolds, enjoy a last-minute shopping spree in Naples's best shopping area, Vomero. Enjoy finding the perfect gift or keepsake to remind you of your wonderful trip to Italy. Browse through boutiques to find unique and stylish fashion pieces to take home. When you need a break, visit a cafe and relax with a cup of coffee or tea.
Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Naples.
If you're in the mood to try something new, consider Trattoria Da Ettore, another top spot with a mouthwatering menu.
You’ll then say farewell to Naples. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!
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