12-Day Italy Road Trip from Pisa to Florence, Rome, Arezzo, Verona, and Milan and surrounding area

Welcome to Pisa, the perfect starting point for your road trip in Italy! Pick up your rental car and let the adventure begin. You will spend 1 night immersing yourself in Pisa's charm before embarking on the next leg of your journey.

Pisa is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Knights' Square or taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Make your way to your chosen hotel. Check-in typically starts between 2 and 4 PM in Pisa. Make yourself at home and enjoy some downtime before heading out again.

As dinnertime approaches, it's time to head out for a bite to eat in Pisa. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Make sure to book a table at Ristorante Capodimonte Pisa, a popular restaurant in Pisa. This acclaimed restaurant and its mouthwatering dishes have earned the admiration of countless food lovers. Alternatively, experience a taste of Pisa at Baribaldi Pisa, a popular local restaurant. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. Another top-rated restaurant to try is Restaurant -Pizzeria Il Mio Capriccio. As a dining spot that gains consistently high praise from guests, it’s an ideal choice to enhance your time to Pisa tonight.

Continue your lively evening at JEFFER cocktails & friends, a perfect place for winding down or revving up the night, depending on which mood you’re in. Le Parisien Wine Bar is another excellent bar that offers a great selection of drinks to suit any mood. If you prefer to go somewhere else, Las Volta cocktailbar ensures a night out tailored to your taste.

Raise a toast to the start of your 12-day road trip in Italy!

Experience an unparalleled adventure on day 2 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 2 vibrant destinations - Pisa and Cascine Vecchie. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Florence. You will spend 2 nights here for some well-deserved relaxation.

Florence’s wonders await as you prepare for another journey on the road, leaving the breathtaking surroundings of Pisa behind. This drive usually takes around 1 hour 28 min. Florence welcomes you with a multitude of unique vacation experiences.

Begin your sightseeing with a visit to Palazzo Blu. This art museum gets 37,457 visitors each year and is rated an average of 4.5 out of 5 stars in 4,244 reviews.

Next up, make your way to Leaning Tower of Pisa. This bell tower has an average rating of 4.7 out of 5 stars from 116,882 reviews. Usually, around 3,200,000 people visit Leaning Tower of Pisa every year.

When you’re ready for your next sight of the day, continue to Piazza del Duomo, Pisa. This square has an average rating of 4.7 out of 5 stars from 104,550 visitors.

Beyond the above-mentioned attractions, you also have the opportunity to visit Pisa Cathedral. This cathedral is rated an average of 4.8 out of 5 stars by 8,361 visitors.

Upon reaching Cascine Vecchie, unwind, observe, and explore. The best things to do, see, and eat are waiting for you.

A top pick for your self-guided sightseeing tour today is Parco Regionale Migliarino, San Rossore, Massaciuccoli. Previous visitors have rated this park an average of 4.4 out of 5 stars in 9,632 reviews.

When you’re done exploring for the day, you’ll drive to Florence, where you'll have a hotel waiting for you. Check in and spend some time relaxing before you head out to explore the city.

As you explore more of Florence, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Dive into a culinary adventure like no other in Florence by booking a table at Enoteca Pinchiorri. This popular restaurant holds , and offers an exceptional menu of italian contemporary cuisine. For another culinary dining option, venture to Santa Elisabetta, celebrated for its delectable creative and mediterranean menu. This acclaimed 2-star Michelin-recipient consistently leaves guests satisfied, ensuring an essential addition to your holiday itinerary. Seeking an alternative? Discover Gucci Osteria da Massimo Bottura, a top local restaurant known for its tantalizing italian contemporary and international menu. With a 1-star Michelin recognition, it promises an exceptional dining experience not to be missed.

After enjoying a fulfilling meal, continue your evening at Manifattura, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, SE·STO on Arno Rooftop Bar offers a welcoming atmosphere for easing into the nightlife. Similarly, Archea Brewery provides an excellent environment for a relaxed and enjoyable evening.

Raise your glass and celebrate another amazing day of your road trip in Italy!

On day 3 of your road trip, you will have an entire day to explore Florence. You’ll stay in Florence for 1 night and discover all the best things to see and do in the area.

Begin your sightseeing with a visit to Cathedral of Santa Maria del Fiore. This church is rated an average of 4.8 out of 5 stars in 76,359 reviews.

Next up, make your way to piazza della Signoria. This square has an average rating of 4.8 out of 5 stars from 66,956 reviews.

When you’re ready for your next sight of the day, continue to Ponte Vecchio. This deck arch bridge has an average rating of 4.7 out of 5 stars from 118,099 visitors.

Beyond the above-mentioned attractions, you also have the opportunity to visit Uffizi Gallery. This national museum is rated an average of 4.7 out of 5 stars by 61,794 visitors. Visiting Uffizi Gallery means you'll be one of 2,011,219 people who do so every year.

If you’re keen to explore even more, then consider a visit to piazzale Michelangelo. This square is a much-appreciated attraction with an average rating of 4.8 out of 5 stars from 77,744 visitors.

Your discoveries in Florence do not have to stop there. Check out the fantastic selection of tours and tickets offered in Florence on this day of your trip. You can select your tours below.

As you explore more of Florence, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Enjoy a delicious meal at Trattoria Da Burde, a top-rated dining destination in Florence. If you're in the mood to try something new, consider Ristorante Buca Mario, another top spot with a mouthwatering menu. You might also want to secure a reservation at Eataly Firenze. With a reputation for consistently satisfied customers, it’s a perfect choice to enhance your stay in Florence this evening.

Say good night to Florence and look forward to another great day of your road trip in Italy!

On day 4 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Nazzano and Vatican City. In the evening, you’ll end up in Rome, where you will stay for 3 nights.

Set your GPS to Nazzano and hit the road. Soak in the beautiful landscapes as you drive and look forward to exploring your next destination. Nazzano beckons with new experiences!

Journey into the unknown at Riserva Naturale Regionale Nazzano Tevere-Farfa, a unique attraction awaiting your visit. This remarkable park has an average rating of 4.4 out of 5 stars from 2,365 reviews.

Once you're ready to continue your road trip, it's time to buckle up and drive, eagerly anticipating your arrival in Vatican City.

Begin your sightseeing with a visit to Saint Peter's Square. This square is rated an average of 4.8 out of 5 stars in 38,954 reviews.

Next up, make your way to St. Peter's Basilica. This major basilica has an average rating of 4.8 out of 5 stars from 131,043 reviews. Usually, around 11,000,000 people visit St. Peter's Basilica every year.

After soaking up all the sights of today's itinerary, you'll be ready to hit the road in the direction of Rome. Rome offers plenty of top-rated hotels and other places to stay on any travel budget. Check in at the hotel of your choice and take some time to relax before you head out to explore.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Rome. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Start your culinary exploration in Rome by securing a reservation at La Pergola. This renowned restaurant holds , and offers an exceptional menu of mediterranean and contemporary cuisine. For another dining delight, visit Il Pagliaccio, celebrated for its delectable creative and innovative menu. This acclaimed 2-star Michelin-recipient consistently leaves guests satisfied, making it a must-visit during your holiday. Looking for a different experience? Discover Enoteca La Torre, a top local spot known for its tantalizing mediterranean and creative menu. With a 2-star Michelin recognition, it guarantees an exceptional dining adventure.

After savoring a delicious meal, step into the vibrant nightlife at La Botticella of Poggi Giovanni, where the evening is just getting started. In the same way, Sant' Eustachio Caffè offers a unique charm perfect for experiencing the local bar scene in Rome. Caffè Portofino is another top-recommended bar that is sure to get you into the mood for some dancing and celebrating.

Relax and recharge in preparation for another adventurous day in Italy!

Day 5 offers a multitude of experiences. You will stay in Rome for 2 nights more, offering you enough time to explore at a relaxed pace.

Take the opportunity to see Basilica di Santa Maria Maggiore. This attraction has an average rating of 4.8 out of 5 stars from 27,678 visitors.

Colosseum is another sightseeing hotspot in the area. This roman amphitheatre has been rated an average of 4.7 out of 5 stars by 328,821 travelers. Up to 7,400,000 people visit Colosseum every year.

Rome is also the home of Roman Forum. Around 114,450 people have rated this square an average of 4.7 out of 5 stars.

Another place you’ll want to visit is Altare della Patria, which hosts up to 1,683,070 visitors every year. With an average rating of 4.8 out of 5 stars from a total of 49,843 reviews, a visit to this architectural structure is a great idea.

This day of your vacation in Rome is also your chance to admire largo di Torre Argentina. This must-visit square enjoys an average rating of 4.5 out of 5 stars from 30,433 reviews.

Immerse yourself in the local scene through top-rated tours and activities. You can choose from a wide variety of easy to challenging tours and easily add them to your travel package below.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Rome. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Enjoy a delicious meal at DEROMA - Farine Romane, a highly-rated dining destination in Rome. If you're eager to try something different, consider La Taverna Italiana, another top spot with a tantalizing menu. You might also want to secure a reservation at Centro. With a reputation for consistently satisfied customers, it’s an excellent choice to enhance your stay in Rome this evening.

Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, The Apartment Bar Roma stands out as an excellent choice for a post-dinner cocktail. Alternatively, Hotel Hassler Roma offers an ideal atmosphere to enjoy the pleasures of the night.

Celebrate another amazing day of your road trip adventure in Italy!

Day 6 of your road trip will take you to the best attractions Rome has to offer. Cherish the 1 night you have left in Rome by discovering the best things there are to see and do in the city.

Journey into the unknown at Circus Maximus, a unique attraction awaiting your visit. This remarkable circus has an average rating of 4.4 out of 5 stars from 44,741 reviews.

When you’re ready to continue your sightseeing, Pantheon is a recommended place to visit. This roman temple is rated an average of 4.8 out of 5 stars in 189,682 reviews. Based on recent data, the attraction hosts 30,000,000 visitors per year.

Another must-see attraction in Rome is Piazza Navona. Rated an average of 4.7 out of 5 stars by 158,771 travelers, this popular tourist destination in Rome offers an experience you will remember.

Campo de' Fiori is another popular stop on travelers' itineraries in Rome. This square promises memorable moments of exploring. Other travelers have rated this attraction 4.4 out of 5 stars in 51,133 reviews.

Lastly, don't miss out on Castel Sant'Angelo. Rated 4.7 out of 5 stars by 72,431 local and international travelers, it's a popular place to visit. This museum gets closer to 918,591 visits every year.

To do something one-of-a-kind on this day of your trip, you can join a tour. You can discover all of the most fun and eye-opening experiences in your destination below and secure your spot here.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Rome.

Don’t miss out on dining at Ristorante Tema, a top-rated dining destination in Rome. If you're in the mood to try something new, consider Maccheroni, another top spot with a mouthwatering menu. You might also want to secure a reservation at RoYaL Art Cafè Roma. With a reputation for consistently satisfied customers, it’s a perfect choice to enhance your stay in Rome this evening.

Savor another day of unforgettable experiences in Italy!

On day 7 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, Rome. When you’re not sightseeing, take time to relax at your selected hotel in Arezzo, where you’ll be staying for 1 night.

After soaking in Rome’s unique atmosphere, jump into the car with a full heart and drive in the direction of your next destination: Arezzo. Expect your car journey to take a minimum of 2 hours 22 min. When you arrive in Arezzo, it's time to take a break from the road.

Begin your sightseeing with a visit to Trevi Fountain. This extraordinary sculpture is rated an average of 4.8 out of 5 stars by 343,494 visitors.

Next, make your way to Piazza di Spagna. This top attraction is a square with an average rating of 4.7 out of 5 stars by 113,658 visitors.

We also recommend a visit to Spanish Steps. This monumental staircase is rated 4.5 out of 5 stars by 57,211 travelers.

If you’re keen to keep exploring, visit piazza del Popolo. This highly recommended sightseeing destination has received an average rating of 4.6 out of 5 stars from 89,807 travelers.

Today is also your chance to spend some time at Villa Borghese. This urban zone of rome is rated an average of 4.6 out of 5 stars by 69,749 travelers.

At the end of the day, you will drive to Arezzo, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

Indulge in a memorable dining experience at one of Arezzo's most popular restaurants, and connect with friendly locals for an authentic adventure.

Enjoy an outstanding dining experience at Octavin, a 1-star Michelin restaurant offering an exceptional creative menu. Alternatively, experience a taste of Arezzo at La Clandestina, a popular local restaurant. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. Another top-rated restaurant to try is Ristorante Logge Vasari. As a dining spot that gains consistently high praise from guests, it’s an ideal choice to enhance your time to Arezzo tonight.

Unwind after your meal by stepping into Liquid Bar. This venue is celebrated for its extensive drink selections and cozy vibes.

Say good night to Arezzo and look forward to another great day of your road trip in Italy!

Embark on another extraordinary experience on day 8 of your road trip in Italy. Today, you will make 1 stop and experience some of the highlights of Bologna. At the end of the day, you will enjoy the comforts of a top-rated hotel in Verona, which will be your home away from home for 1 night.

Embrace the thrill of the open road as you wave goodbye to Arezzo and set your GPS to Bologna. While on the road, immerse yourself in your favorite road trip tunes or sample the sounds from a local radio station. This car ride usually takes around 2 hours 11 min. Upon reaching Bologna, unwind, observe, and explore. The best things to do, see, and eat are waiting for you.

A top pick for your self-guided sightseeing tour today is Piazza Santo Stefano. Previous visitors have rated this square an average of 4.8 out of 5 stars in 7,617 reviews.

Two Towers is a local recommendation that you also can pay a visit today. This tower is rated an average of 4.7 out of 5 stars in 25,975 reviews.

Another attraction you won't want to miss is Piazza Maggiore. This square is rated an average of 4.7 out of 5 stars in 64,523 reviews.

Fountain of Neptune, Bologna is another outstanding experience in Bologna. Around 3,952 travelers have rated this fountain an average of 4.7 out of 5 stars.

When you’re done exploring for the day, you’ll drive to Verona, where you'll have a hotel waiting for you. Check in and spend some time relaxing before you head out to explore the city.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Verona.

Experience a harmony of flavors at Osteria Mondo d'Oro in Verona by securing a reservation in advance. Known for its Bib Gourmand status, Osteria Mondo d'Oro offers a delightful variety of dishes highlighting its delicious italian and seasonal menu. If you're seeking an alternative culinary experience, be sure to explore Casa Perbellini 12 Apostoli, a highly recommended restaurant known for its enticing creative and contemporary cuisine. This popular 2-star Michelin-awarded venue consistently exceeds expectations, ensuring a memorable holiday experience. Ready for another culinary adventure? Indulge your senses at Il Desco, a highly acclaimed restaurant celebrated for its exceptional italian contemporary menu.

Extend your evening after a delightful meal by visiting Archivio, which offers the perfect atmosphere for a night out. Moreover, La Segreteria Café is another popular option for a drink or two. Likewise, Duchi Café also provides a great ambiance for reminiscing about the day and raising a toast to your vacation.

Raise your glass to another unforgettable day in Italy!

Dive into day 9 of your remarkable road trip in Italy. Today you will explore Verona, Valeggio sul Mincio, and Ronchi, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Milan. You’ll stay here for 2 nights.

Continue your road trip and head to your next destination, Valeggio sul Mincio. This car ride takes around 50 min.

Start your sightseeing with a visit to Verona Arena. This opera house is rated an average of 4.7 out of 5 stars from 123,818 visitors. Verona Arena welcomes around 195,540 visitors every year.

Continue your road trip and head to your next destination, Valeggio sul Mincio. This car ride takes around 50 min.

Journey into the unknown at Parco Giardino Sigurtà, a unique attraction awaiting your visit. This remarkable park has an average rating of 4.6 out of 5 stars from 27,387 reviews.

After soaking up all the sights of today's itinerary, you'll be ready to hit the road in the direction of Milan. Milan offers plenty of top-rated hotels and other places to stay on any travel budget. Check in at the hotel of your choice and take some time to relax before you head out to explore.

As dinnertime approaches, it's time to head out for a bite to eat in Milan. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Set out on a gastronomic journey in Milan by reserving a table at Enrico Bartolini al Mudec. Renowned for its , this restaurant presents an outstanding menu of creative cuisine. For a different taste, head over to Seta by Antonio Guida, renowned for its delectable international and contemporary dishes. This distinguished 2-star Michelin-recipient is a favorite among guests, making it a worthy addition to your holiday plans. Craving more culinary excitement? Explore Il Luogo Aimo e Nadia, a highly rated local gem known for its exquisite italian contemporary and modern menu. With a 1-star Michelin acclaim, it promises a dining experience you won't want to miss. With its reputation for pleasing customers, it’s a fantastic choice for tonight in Milan.

Round off your dining experience by visiting Nottingham Forest, a prime location for a drink. Alternatively, explore the distinctive characteristics of Armani/Bamboo Bar, a bar catering to every mood and preference. Mag Cafe likewise offers a unique atmosphere, perfect for a memorable night out.

Relax and reminisce about your day in Italy and look forward to more memorable moments to come!

Day 10 of your road trip across Italy promises a magnificent time exploring Milan. You have 1 night left in Milan. Take the opportunity to experience more of the best attractions and activities in the city.

Start your sightseeing with a visit to Duomo di Milano Museum. This art museum is rated an average of 4.8 out of 5 stars from 138,554 visitors. Duomo di Milano Museum welcomes around 341,609 visitors every year.

Galleria Vittorio Emanuele II is another popular attraction you could visit today. This commercial gallery has a rating of 4.7 out of 5 stars from 91,394 visitors.

La Scala is also highly recommended by travelers. This opera house has a rating of 4.7 out of 5 stars from 26,219 visitors.

Pinacoteca di Brera is an attraction you won’t want to miss. Around 417 people visit this place every year. This art museum is rated an average of 4.7 out of 5 stars in 26,077 reviews.

Another attraction you have the opportunity to visit today is Piazza Gae Aulenti. This square has received an average rating of 4.6 out of 5 stars from 30,398 travelers.

One of the most unique ways of discovering what else Milan has to offer is by going on a top-rated tour. Be sure to check out all the experiences Milan offers and add your favorites to your Italy travel package below.

After a day of adventure, treat yourself to an exquisite dinner at one of Milan's best restaurants.

Make sure to reserve a table at Nero 9, an iconic dining spot in Milan. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Ristorante la Brisa, a popular restaurant in Milan. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of UNAHOTELS Cusani Milano, a hidden gem nestled in Milan. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Keep the excitement of the evening going by going to a bar or two. Kilburn Cocktail Bar Milano is an excellent place to start. You could also check out Bar Frida, offering a different kind of charm. A last recommendation for the day is The Friends Pub Milano. This bar promises an enjoyable experience with tasty drinks and a vibrant setting.

Raise your glass to another unforgettable day in Italy!

Experience an unparalleled adventure on day 11 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 2 vibrant destinations - Sarzana and Milan. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Pisa. You will spend 1 night here for some well-deserved relaxation.

When you’re ready to jump back into the car and say goodbye to Milan, you’ll hit the road in the direction of Sarzana. This drive usually takes around 2 hours 46 min. When you arrive, enjoy some sightseeing.

Your sightseeing of the day begins at Sarzana Cathedral Santa Maria Assunta, a remarkable church where it’s easy to get lost in exploration. This top attraction is rated an average of 4.5 out of 5 stars in 584 reviews.

When you’re ready to jump back into the car and say goodbye to Milan, you’ll hit the road in the direction of Sarzana. This drive usually takes around 2 hours 46 min. When you arrive, enjoy some sightseeing.

An excellent attraction to start your day with is Sforzesco Castle Art Library. This library is rated an average of 4.6 out of 5 stars in 68,714 reviews.

Continue your journey at Parco Sempione. This park is rated 4.6 out of 5 stars by 72,914 travelers from near and far.

Milan is also the home of Arch of Peace. This monument has an average rating of 4.6 out of 5 stars from 27,502 visitors.

At the end of the day, you will drive to Pisa, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a day of adventure, treat yourself to an exquisite dinner at one of Pisa's best restaurants.

As a top-rated it is an ideal choice in the city. Enjoy a lovely meal at Ristorante alle Bandierine, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Barrique Cocktail And Bistrot is another top choice with a popular menu. You could also check for a table at Filter Coffee Lab. As an establishment that gains consistently high praises from customers, it’s an ideal choice in Pisa tonight.

Continue the enjoyment post-dinner at Bar Mocambo, a cherished local gathering spot renowned for its welcoming atmosphere. Similarly, Tree offers a vibrant space for indulging in well-crafted drinks and engaging conversation. You may also want to check out Chupiteria. This bar is a favorite among both locals and visitors looking for a delightful evening out filled with laughter and fun.

Head back to your accommodation in Pisa and get some rest in preparation for another magical day of your road trip in Italy!

Day 12 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Pisa before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

On your last day in Italy, take time to indulge in shopping at Pisa’s popular marketplace. Thanks to your accommodation’s strategic location, the city’s bustling commercial district is only a stone’s throw away, giving you ample time to leisurely explore the area, filled with local shops.

Take time to find the perfect present, reminding you of the charms of Italy. Each store here is brimming with unique finds. These souvenirs will help you treasure your memories of Italy forever.

Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Pisa.

If you're in the mood to try something new, consider Kiste' - La Pizza Artigianale. It's the second restaurant coming from the tower. , another top spot with a mouthwatering menu.

You’ll then say farewell to Pisa. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!