12-Day Italy Self-Drive Road Trip With Itinerary from Rome to Florence, Lucca, La Spezia, Bologna, and Venice

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Photo of piazza de spagna in Rome, Italy.
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Description

Experience the freedom of the open road on an unforgettable 12-day road trip in Italy! Embark on a self-drive tour that caters to every traveler, featuring destinations like Rome, Florence, Pisa, Lucca, Riomaggiore, La Spezia, Manarola, Corniglia, Bologna, and Venice.

This perfectly planned road trip itinerary takes you through some of the best places to see in Italy. You will spend 3 nights in Rome, 2 nights in Florence, 1 night in Lucca, 2 nights in La Spezia, 2 nights in Bologna, and 1 night in Venice. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Rome, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Trevi Fountain and Colosseum are just a couple of the bucket-list attractions that await your discovery.

As you hit the open road and drive through Rome, Florence, Pisa, Lucca, Riomaggiore, La Spezia, Manarola, Corniglia, Bologna, and Venice, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.

Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!

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Driver’s age is 30 - 65
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Pick-up: 10:00
Drop-off: 10:00

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Day 1

Day 1

  • Rome - Arrival day
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  • Piazza Navona
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Welcome to Rome, the perfect starting point for your road trip in Italy! Pick up your rental car and let the adventure begin. You will spend 2 nights discovering what to see in Rome before embarking on the next leg of your journey.

Rome is a beautiful city with plenty to discover. Taking a stroll in the city center is a great alternative. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Find your way to your hotel in Rome. We recommend choosing a hotel in a central location for easy exploring. Check-in typically starts between 2 and 4 PM at hotels in Italy. Settle in and make plans for the evening.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Rome, it's often a good idea to reserve a table in advance.

Raise a toast to the start of your 12-day road trip in Italy!

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Day 2

Day 2

  • Rome
  • More

Drive 10 km, 1 hour 22 min

  • Colosseum
  • Roman Forum
  • Trevi Fountain
  • Spanish Steps
  • Villa Borghese
  • Monti
  • More

You have 1 night left in Rome. Take the opportunity to experience more of the best attractions and activities in the city.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

Experience shopping bliss at Rome as you explore Trastevere. Take a leisurely stroll through unique boutique shops and stores, where local treasures are waiting to be found. Don't miss the chance to discover artisan crafts that reflect the fascinating culture of Italy. Beyond shopping, Trastevere offers more options, including unique attractions, key services, and vibrant events.

Indulge in a memorable dining experience at one of Rome's most popular restaurants, and connect with friendly locals for a true cultural experience.

Raise your glass and celebrate another amazing day of your road trip in Italy!

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Day 3

Day 3

  • Rome
  • Florence
  • More

Drive 278 km, 3 hours 22 min

  • Bargello National Museum
  • Uffizi Gallery
  • Ponte Vecchio
  • Loggia dei Lanzi
  • Palazzo Vecchio
  • piazza della Signoria
  • More

Experience an unparalleled adventure on day 3 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 place, which are Florence. At the end of the day, you will retreat to the hotel of your choice in Florence, where will spend 2 nights.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Florence. Florence offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a day of adventure, treat yourself to an exquisite dinner at one of Florence's best restaurants.

Take some time to reflect on your day and savor another beautiful night in Italy.

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Day 4

Day 4

  • Florence
  • More

Drive 8 km, 1 hour 14 min

  • Central Market
  • Galleria dell'Accademia
  • Cathedral of Santa Maria del Fiore
  • Basilica of Santa Croce in Florence
  • piazzale Michelangelo
  • Oltrarno
  • More

Day 4 offers an itinerary packed with the best things to see in Rome. You’ll stay in Florence for 1 night more, offering you enough time to explore at a relaxed pace.

A visit to Oltrarno is a must on the agenda today. This neighborhood is full of hidden gems and character, perfect for a leisurely stroll. Plus, you’ll be close to some of the city’s most famous sights.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Florence. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Raise your glass to another unforgettable day in Italy!

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Day 5

Day 5

  • Florence
  • Lucca
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Drive 107 km, 2 hours 11 min

  • Campo santo
  • Piazza del Duomo, Pisa
  • Pisa Cathedral
  • Leaning Tower of Pisa
  • Walls of Lucca
  • Piazza dell'Anfiteatro
  • More

On day 5 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 2 destinations, including Pisa and Lucca. When you’re not sightseeing, take time to relax at your chosen hotel in Lucca, where you’ll be staying for 1 night.

At the end of the day, you will drive to Lucca, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Lucca. Enjoy a relaxing evening as you savor delicious local cuisine.

Head back to your accommodation in Lucca and get some rest to prepare for another magical day of your road trip in Italy.

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Day 6

Day 6

  • Lucca
  • La Spezia
  • More

Drive 104 km, 2 hours

  • Castle of Riomaggiore
  • Riomaggiore
  • Church of San Giovanni Battista of Riomaggiore
  • More

On day 6 of your road trip in Italy, your travel plans include 1 stop at the most scenic, wondrous, and interesting places in the region. Riomaggiore are on today's agenda. In the evening, you’ll end up in La Spezia, where you will stay for 2 nights.

When you’re done exploring for the day, you’ll drive to your hotel in La Spezia. Check in and relax before you head out to tour the city.

Indulge in a memorable dining experience at one of La Spezia's most popular restaurants, and connect with friendly locals for a true cultural experience.

Say good night to La Spezia and look forward to another great day of your road trip in Italy!

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Day 7

Day 7

  • La Spezia
  • More

Drive 57 km, 1 hour 46 min

  • Manarola Overlook Viewpoint
  • Cinque Terre National Park
  • Sentiero Azzurro
  • More

On day 7 of your road trip, you’ll start and end your day in La Spezia, where you have 1 night left to stay.

When you’re done exploring for the day, you’ll return to La Spezia and your accommodation.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in La Spezia, it's often a good idea to reserve a table in advance.

Raise your glass to another unforgettable day in Italy!

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Day 8

Day 8

  • La Spezia
  • Bologna
  • More

Drive 220 km, 2 hours 49 min

  • Pinacoteca Nazionale di Bologna
  • Palazzo Grassi, Bologna
  • Bologna Cathedral
  • Fountain of Neptune, Bologna
  • Piazza Maggiore
  • Palazzo d'Accursio
  • More

Dive into day 8 of your remarkable road trip in Italy. Today you'll explore 1 destination, including Bologna. At the end of the day, you’ll unwind at one of the finest accommodations in Bologna, where you'll spend 2 nights.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Bologna. Bologna offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Bologna, it's often a good idea to reserve a table in advance.

Get a good night's sleep and look forward to another great day on the road in Italy!

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Day 9

Day 9

  • Bologna
  • More

Drive 3 km, 42 min

  • Two Towers
  • Piazza Santo Stefano
  • Portici di Bologna
  • Porta Castiglione
  • More

You’ll stay in Bologna for 1 night.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

After a day of adventure, treat yourself to an exquisite dinner at one of Bologna's best restaurants.

Take some time to reflect on your day and savor another beautiful night in Italy.

Read more
Day 10

Day 10

  • Bologna
  • Venice
  • More

Drive 162 km, 2 hours 54 min

  • Bridge of Sighs
  • Doge's Palace
  • St Mark's Basilica
  • St Mark's Campanile
  • Piazza San Marco
  • Grassi Palace
  • More

Your itinerary for day 10 of your road trip in Italy includes 1 stop and features some of the highlights of Venice. At the end of the day, enjoy the comforts of a top-rated hotel in Venice, where you'll spend 1 night.

At the end of the day, you will drive to Venice, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Venice. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Raise your glass and celebrate another amazing day of your road trip in Italy!

Read more
Day 11

Day 11

  • Venice
  • Rome
  • More

Drive 541 km, 6 hours 15 min

  • Rialto Bridge
  • Palazzo Contarini del Bovolo
  • Campo Sant'Angelo
  • Peggy Guggenheim Collection
  • Basilica S.Maria Gloriosa dei Frari
  • More

Experience an unparalleled adventure on day 11 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 place, which are Venice. At the end of the day, you will retreat to the hotel of your choice in Rome, where will spend 1 night.

When you’re done exploring for the day, you’ll drive to your hotel in Rome. Check in and relax before you head out to tour the city.

Rome is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Rome.

Relax and look forward to more memorable moments to come!

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Day 12

Day 12

  • Rome - Departure day
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  • Pantheon
  • More

Day 12 of your road trip in Italy is your departure day. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!

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How it works

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Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

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Your trip is protected, personalized, and priced right. No surprises, no stress.

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