12-Day Italy Road Trip from Rome traveling west to Florence, Pisa, and Perugia

Day 2 of your road trip across Italy promises a magnificent time exploring Rome. You have 3 nights left in Rome. Take the opportunity to experience more of the best attractions and activities in the city.

Make Colosseum your first stop of the day. Previous visitors have rated this roman amphitheatre an average of 4.7 out of 5 stars in 328,821 reviews. More than 7,400,000 people visit this place of interest every year.

Next up, make a stop at Roman Forum. With an average rating of 4.7 out of 5 stars by 114,450 visitors, it's easy to understand why so many people visit this square every year.

Pantheon is another attraction you can visit on this day of your vacation. This roman temple has an average rating of 4.8 out of 5 stars by 189,682 visitors. Up to 30,000,000 travelers come to Rome every year to see Pantheon with their own eyes.

When you’re finished at Pantheon, the perfect next stop is Piazza Navona. This square is rated an average of 4.7 out of 5 stars in 158,771 reviews.

If you’re keen to explore even more, then consider a visit to Castel Sant'angelo. This museum is a top place to visit, with a rating of 4.7 out of 5 stars from 72,431 reviews. Castel Sant'angelo hosts around 918,591 visitors every year.

To immerse yourself in more memorable moments in Rome, check out the best-rated tours the region offers. You can discover and choose from all of the top-rated activities you can do on this day in Rome below.

As you explore more of Rome, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Experience a symphony of flavors at La Pergola in Rome by securing a reservation in advance. Renowned for its 3-star Michelin distinction, La Pergola delights its guests with its exceptional variety of meals showcasing delicious mediterranean, and contemporary cuisine. For a palate-pleasing alternative, make sure to dine at Il Pagliaccio, acclaimed for its delectable creative, and innovative specialties. This local 2-star Michelin establishment consistently satisfies guests, ensuring an unforgettable holiday experience. Want to go on another culinary journey? Delight your senses at Enoteca La Torre, a top-rated restaurant known for its outstanding menu. Known as a top-rated 2-star Michelin establishment, it's a top choice for mediterranean, and creative cuisine in the city.

Keep the evening going at The Apartment Bar Roma, a great choice for enjoying the after-dinner hours with a drink. You could also go to Hotel Hassler Roma, which offers a similarly pleasant setting and great drinks.

Relax and reminisce about your day in Italy and look forward to more memorable moments to come!

Day 3 offers a multitude of experiences. You will stay in Rome for 2 nights more, offering you enough time to explore at a relaxed pace.

An excellent attraction to start your day with is Trevi Fountain. This sculpture is rated an average of 4.8 out of 5 stars in 343,494 reviews.

Continue your journey at Piazza Di Spagna. This square is rated 4.7 out of 5 stars by 113,658 travelers from near and far.

Rome is also the home of Spanish Steps. This monumental staircase has an average rating of 4.5 out of 5 stars from 57,211 visitors.

You can continue your self-guided sightseeing tour at Piazza Del Popolo. Rated 4.6 out of 5 stars by 89,807 visitors, a visit to this top sight is time well spent.

Lastly, don't miss out on Villa Borghese. With an average rating of 4.6 out of 5 stars from 69,749 reviews, it’s hard to refuse the opportunity to see this urban zone of rome.

One of the most unique ways of discovering what else Rome has to offer is by going on a top-rated tour. Be sure to check out all the experiences Rome offers and add your favorites to your Italy travel package below.

Indulge in a memorable dining experience at one of Rome's most popular restaurants, and connect with friendly locals for an authentic adventure.

Treat yourself to a delicious dinner at Ristorante Tema, an excellent option for tonight's dining. Looking for something different? Maccheroni offers a tantalizing alternative with its diverse menu. And don’t miss RoYaL Art Cafè Roma. With its reputation for pleasing customers, it’s a fantastic choice for tonight in Rome.

Get a good night's sleep and look forward to another great day on the road in Italy!

On day 4 of your road trip in Italy, you’ll start and end your day in Vatican City, but spend the day exploring what’s beyond the city. Since you will return to Rome for 1 night more, there’s no need to rush. Experience Vatican City to the fullest today with this curated day itinerary!

Vatican City’s wonders await as you prepare for another journey on the road, leaving the breathtaking surroundings of Rome behind. This drive usually takes around 11 min. Vatican City welcomes you with a multitude of unique vacation experiences.

Begin your sightseeing with a visit to St. Peter's Basilica. This major basilica gets 11,000,000 visitors each year and is rated an average of 4.8 out of 5 stars in 131,043 reviews.

Next up, make your way to Sistine Chapel. This chapel has an average rating of 4.7 out of 5 stars from 52,083 reviews.

When you’re ready for your next sight of the day, continue to Saint Peter's Square. This square has an average rating of 4.8 out of 5 stars from 38,954 visitors.

Beyond the above-mentioned attractions, you also have the opportunity to visit Vatican Museums. This art museum is rated an average of 4.6 out of 5 stars by 133,310 visitors. Visiting Vatican Museums means you'll be one of 1,612,530 people who do so every year.

When you’re done exploring for the day, you’ll return to Rome and your accommodation.

As dinnertime approaches, it's time to head out for a bite to eat in Rome. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Enjoy a delicious meal at Harry's Bar, a top-rated dining destination in Rome. If you're in the mood to try something new, consider Ristorante Amedeo, another top spot with a mouthwatering menu. You might also want to secure a reservation at VinAllegro. With a reputation for consistently satisfied customers, it’s a perfect choice to enhance your stay in Rome this evening.

Celebrate another amazing day of your road trip adventure in Italy!

Embark on another extraordinary experience on day 5 of your road trip in Italy. Today, you will make 1 stop and experience some of the highlights of Orvieto. At the end of the day, you will enjoy the comforts of a top-rated hotel in Florence, which will be your home away from home for 3 nights.

Set your GPS to Orvieto and hit the road. Expect a journey of approximately 1 hour 38 min without stops. Soak in the beautiful landscapes as you drive and look forward to exploring your next destination. Orvieto beckons with new experiences!

Drop by the renowned Orvieto Cathedral. This popular catholic cathedral has been rated an average of 4.8 out of 5 stars by 15,057 visitors.

Another unforgettable place to experience is Orvieto Underground. Rated 4.6 out of 5 stars by 1,517 visitors, this archaeological site deserves a spot on today's sightseeing itinerary.

After soaking in Rome’s unique atmosphere, jump into the car with a full heart and drive in the direction of your next destination: Orvieto. Expect your car journey to take a minimum of 1 hour 38 min. When you arrive in Orvieto, it's time to take a break from the road.

When you’re ready for some sightseeing, make your way to Well Of St. Patrick. This much-appreciated sightseeing destination is rated 4.5 out of 5 stars in 14,274 reviews.

After soaking up all the sights of today's itinerary, you'll be ready to hit the road in the direction of your accommodation in Florence. Florence offers plenty of top-rated hotels and other places to stay on any travel budget. Take some time to relax before you head out to explore.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Florence. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Treat yourself to an extraordinary dining experience at Enoteca Pinchiorri, a 3-star Michelin restaurant offering an incredible italian contemporary menu. Alternatively, if your taste buds call for something different, Santa Elisabetta is one of the best restaurants for creative, and mediterranean cuisine in Florence. This 2-star Michelin-awardee earns consistently high praises from guests. We also recommend checking out the menu at Gucci Osteria da Massimo Bottura. As a top-rated establishment with 1 Michelin star, it is an ideal choice for italian contemporary, and international cuisine in the city.

If you’re not ready to end the night just yet, Manifattura offers a perfect venue to relax and savor a drink. Similarly, Se·sto On Arno Rooftop Bar is well-suited for those looking to unwind in a social setting. Archea Brewery is another excellent spot to enjoy a nightcap after a delightful meal.

Raise your glass to another unforgettable day in Italy!

On day 6 of your road trip, you will have an entire day to explore Florence. You’ll stay in Florence for 2 nights and discover all the best things to see and do in the area.

Drop by the renowned Piazza Della Signoria. This popular square has been rated an average of 4.8 out of 5 stars by 66,956 visitors.

Another unforgettable place to experience is Uffizi Gallery. Rated 4.7 out of 5 stars by 61,794 visitors, this national museum deserves a spot on today's sightseeing itinerary.

We also recommend a visit to Ponte Vecchio. This deck arch bridge has been rated an average of 4.7 out of 5 stars in 118,099 reviews.

Another favorite attraction in the area is Pitti Palace, drawing over 198,270 yearly visitors. This art museum and popular place of interest enjoys a rating of 4.6 out of 5 stars from 23,445 local and international travelers.

If you’re keen to explore even more, then consider a visit to The Boboli Gardens. With an average rating of 4.2 out of 5 stars from 25,341 travelers, this park is an attraction many avid travelers highly recommend visiting while in Florence.

If you have an appetite for more adventure, check out the fantastic selection of tours and tickets offered in Florence on this day of your trip. You'll find the most recommended ones below.

As dinnertime approaches, it's time to head out for a bite to eat in Florence. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Don’t miss out on dining at Trattoria Da Burde, a top-rated dining destination in Florence. If you're in the mood to try something new, consider Ristorante Buca Mario, another top spot with a mouthwatering menu. You might also want to secure a reservation at Eataly Firenze. With a reputation for consistently satisfied customers, it’s a perfect choice to enhance your stay in Florence this evening.

As the sun sets on another day of adventure, rest up and recharge for the next leg of your road trip in Italy.

Day 7 of your road trip will take you to the best attractions Florence has to offer. Cherish the 1 night you have left in Florence by discovering the best things there are to see and do in the city.

A top pick for your self-guided sightseeing tour today is David. Previous visitors have rated this statue an average of 4.8 out of 5 stars in 10,476 reviews.

Galleria Dell'accademia is a local recommendation that you also can pay a visit today. This national museum is rated an average of 4.6 out of 5 stars in 34,429 reviews. The attraction welcomes 1,719,645 visitors every year.

Another attraction you won't want to miss is Basilica Of Santa Croce In Florence. This church is rated an average of 4.7 out of 5 stars in 28,544 reviews.

Piazzale Michelangelo is another outstanding experience in Florence. Around 77,744 travelers have rated this square an average of 4.8 out of 5 stars.

The attraction gets an estimated 1,719,645 visitors every year.

Immerse yourself in the local scene through top-rated tours and activities. You can choose from a wide variety of easy to challenging tours and easily add them to your travel package below.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Florence. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Enjoy a delicious meal at Tijuana, a top-rated dining destination in Florence. If you're in the mood to try something new, consider Djària - American Bar, another top spot with a mouthwatering menu. You might also want to secure a reservation at Ristorante Buca Niccolini. With a reputation for consistently satisfied customers, it’s a perfect choice to enhance your stay in Florence this evening.

Relax and recharge in preparation for another adventurous day in Italy!

On day 8 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, Florence. When you’re not sightseeing, take time to relax at your selected hotel in Pisa, where you’ll be staying for 1 night.

A top pick for your self-guided sightseeing tour today is Cathedral Of Santa Maria Del Fiore. Previous visitors have rated this church an average of 4.8 out of 5 stars in 76,359 reviews.

Basilica Of San Lorenzo is a local recommendation that you also can pay a visit today. This parish church is rated an average of 4.6 out of 5 stars in 9,628 reviews.

Another attraction you won't want to miss is Central Market. This sightseeing destination is rated an average of 4.4 out of 5 stars in 43,100 reviews.

Basilica Di Santa Maria Novella, Firenze (fi) is another outstanding experience in Florence. Around 23,075 travelers have rated this archives an average of 4.7 out of 5 stars.

At the end of the day, you will drive to Pisa, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

Indulge in a memorable dining experience at one of Pisa's most popular restaurants, and connect with friendly locals for an authentic adventure.

Treat yourself to a delicious dinner at Ristorante Capodimonte Pisa, an excellent option for tonight's dining. Looking for something different? Baribaldi Pisa offers a tantalizing alternative with its diverse menu. And don’t miss Restaurant -Pizzeria Il Mio Capriccio. With its reputation for pleasing customers, it’s a fantastic choice for tonight in Pisa.

After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at Jeffer Cocktails & Friends, a well-loved spot among locals and tourists. Or, head to Le Parisien Wine Bar. This bar boasts a welcoming environment that is perfect for winding down. You could also continue your night at Las Volta Cocktailbar, another top-rated place in the area.

Head back to your accommodation in Pisa and get some rest in preparation for another magical day of your road trip in Italy!

Experience an unparalleled adventure on day 9 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 vibrant destinations - Pisa. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Perugia. You will spend 2 nights here for some well-deserved relaxation.

Be one of the day’s first visitors at Knights' Square. This square is rated an average of 4.5 out of 5 stars by 9,051 visitors.

When you’re finished at Knights' Square, head to Leaning Tower Of Pisa. This one-of-a-kind bell tower is rated an average of 4.7 out of 5 stars in 116,882 reviews. Every year, approximately 3,200,000 travelers come here to experience the bell tower for themselves.

Beyond the above-mentioned attractions, you also have the opportunity to visit Pisa Cathedral. This cathedral is rated an average of 4.8 out of 5 stars by 8,361 visitors.

If you’re keen to explore more, then consider a visit to Piazza Del Duomo, Pisa. This square is a much-appreciated attraction with an average rating of 4.7 out of 5 stars from 104,550 visitors.

To round off your sightseeing experience, make your way to Campo Santo. This famous cemetery is rated an average of 4.6 out of 5 stars by 586 travelers.

When you’re done exploring for the day, you’ll drive to Perugia, where you'll have a hotel waiting for you. Check in and spend some time relaxing before you head out to explore the city.

As you explore more of Perugia, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Savor the flavors at Ristorante Settimo Sigillo, a top pick for dinner tonight. Alternatively, Bar Pellas beckons with its unique menu offerings. Also, consider La Taverna. With its consistent customer satisfaction, it’s an excellent option for dining in Perugia tonight.

Extend your evening after a delightful meal by visiting Tommi Bar, which offers the perfect atmosphere for a night out. Moreover, Valentina is another popular option for a drink or two. Likewise, Caffe Dal Perugino also provides a great ambiance for reminiscing about the day and raising a toast to your vacation.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in Italy.

Wake up to day 10 of your extraordinary road trip in Italy. With 1 night left in Perugia, we encourage you to seize the day and discover the unexplored beauty of the city’s surroundings!

Fasten your seatbelt and make your way to your next stop. Santa Maria degli Angeli, home to many well-known sights in the region, is a lovely destination on today’s itinerary. Keep in mind that your travel time from Perugia to Santa Maria degli Angeli may take around 32 min without traffic disruptions. Upon arrival in Santa Maria degli Angeli, we highly recommend checking out some of the top attractions.

When you’re ready for some sightseeing, make your way to Basilica Of San Francesco D'assisi. This much-appreciated papal basilica is rated 4.9 out of 5 stars in 33,258 reviews.

Next up is Cathedral Of San Rufino. This church has an average rating of 4.6 out of 5 stars from 3,893 visitors.

Another top sightseeing recommendation is Basilica Di Santa Chiara. This minor basilica has been rated 4.7 out of 5 stars in 9,628 reviews.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Perugia.

Indulge in a memorable dining experience at one of Perugia's most popular restaurants, and connect with friendly locals for an authentic adventure.

Savor the flavors at Ristorante del Sole, a top pick for dinner tonight. Alternatively, Al Mangiar Bene beckons with its unique menu offerings. Also, consider Elfo Pub Perugia. With its consistent customer satisfaction, it’s an excellent option for dining in Perugia tonight.

Round off your dining experience by visiting Caffè Fortebraccio, a prime location for a drink. Alternatively, explore the distinctive characteristics of Caffe Del Banco, a bar catering to every mood and preference. Dempsey's Perugia likewise offers a unique atmosphere, perfect for a memorable night out.

Relax and reminisce about your day in Italy and look forward to more memorable moments to come!