12-Day Italy Self-Drive Road Trip With Itinerary from Trieste to Venice, Florence, Siena, Rome, and Santa Maria degli Angeli

On day 2 of your road trip, you’ll start and end your day in Trieste, where you still have 1 night left. You'll spend part of the day exploring places of interest outside the immediate city, including Miramare / Miramar and Trieste.

Check out the intriguing street, Canale Ponterosso Trieste. Afterward, continue to Palazzo Gopcevich, a palace every traveler should visit. As you explore Trieste’s charming streets, take in the lively atmosphere and get to know the character of the village.

Next, make your way to Molo Audace. This curiosity-inducing pier is an essential stop. Following that, head to Piazza Unità D'italia, another must-visit site that will enhance your experience. Don’t forget to stop by Cattedrale Di San Giusto Martire, a beloved church in the village.

Continue your road trip and head to your next destination, Miramare / Miramar. This car ride takes around 18 min.

When you're ready for some sights, head to Miramare Castle, an interesting castle in Miramare / Miramar. Explore its respected features at your own pace before you continue your journey.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Trieste.

Indulge in a memorable dining experience at one of Trieste's most popular restaurants, and connect with friendly locals for a true cultural experience.

Enjoy a delicious meal at Rustiko, a highly-rated dining destination in Trieste. If you're eager to try something different, consider Caffè San Marco, another top spot with a tantalizing menu. You might also want to secure a reservation at Osteria Marise. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Trieste this evening.

After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at Mast, a well-loved spot among locals and tourists. Or, head to Urbanis. This bar boasts a welcoming environment that is perfect for winding down. You could also continue your night at Coktail Bar Trieste | La Preferita, another top-rated place in the area.

Take some time to reflect on your day and savor another beautiful night in Italy.

On day 3 of your road trip in Italy, your travel plans include 1 stop at the most scenic, wondrous, and interesting places in the region. Venice are on today's agenda. In the evening, you’ll end up in Venice, where you will stay for 2 nights.

Throughout the day, make sure to take breaks to appreciate the surroundings.

After soaking in Trieste’s unique atmosphere, jump into the car with a full heart and drive in the direction of your next destination: Venice. Expect your car journey to take a minimum of 2 hours 17 min. When you arrive in Venice, it's time to take a break from the road.

For a more meaningful self-guided tour of the city's best attractions, visit Bridge Of Sighs, a notable monument that is sure to impress. Take in the surroundings and enjoy the freedom of exploring at your own pace before you continue your journey. Next, head to Doge's Palace and admire its romantic features.

When you’re ready, continue to St Mark's Basilica, an interesting church beloved by locals and tourists alike. Don't miss out on Piazza San Marco, another highlight of the area that promises a memorable visit. Not far away, you’ll also find Palazzo Contarini Del Bovolo, a romantic place to see that you won’t regret spending some extra time discovering.

At the end of the day, you will drive to Venice, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Venice, it's often a good idea to reserve a table in advance.

Dine in style at Bauer Hotel, a top recommendation for dinner tonight. Or, for a change of pace, L'Osteria Le Guglie boasts a menu that's sure to impress. Also, be sure to check out Corner Pub. Known as a local hotspot, it’s a great choice for tonight in Venice.

Cap off your dinner by heading to Al Parlamento, ideal for a leisurely evening with a drink in hand. The Caffe Rosso is another bar that offers an enjoyable setting. Similarly, Adagio is also a popular place to go on a night out, perfect for relaxing and socializing.

Savor another day of unforgettable experiences in Italy!

On day 4 of your road trip in Italy, you’ll start and end your day in Venice, but spend the day exploring what’s beyond the city. Since you still have 1 night to spend in Venice, there’s no need to rush. Experience Murano and Venice to the fullest today with this curated day itinerary.

At the top of the list of things to do today is to explore Cannaregio, a neighborhood that captures the true essence of Murano. Take your time to uncover its best sides and enjoy its proximity to many of the area’s best attractions.

Santa Maria Gloriosa Dei Frari is must-visit church and a great option for a daytime tour of the area. Continue your journey to Gallerie Dell'accademia, a curiosity-inducing art gallery, located just a leisurely stroll away. Next, head to Peggy Guggenheim Collection, an enchanting art gallery, also available for your discovery today.

When you’re ready to jump back into the car and say goodbye to Venice, you’ll hit the road in the direction of Murano.

Our first attraction recommendation in Murano is Murano Lighthouse, an intriguing lighthouse that draws attention for its romantic features.

When you’re done exploring for the day, you’ll return to Venice and your accommodation.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Venice, it's often a good idea to reserve a table in advance.

Make sure to reserve a table at Generator Venice, an iconic dining spot in Venice. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Nevodi, a popular restaurant in Venice. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Ristorante La Piazza, a hidden gem nestled in Venice. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, Il Mercante stands out as an excellent choice for a post-dinner cocktail. Alternatively, The Irish Pub Venezia offers an ideal atmosphere to enjoy the pleasures of the night. Ai Stagneri is also a great option that provides a perfect setting for a relaxing evening.

Savor another day of unforgettable experiences in Italy!

Dive into day 5 of your remarkable road trip in Italy. Today you'll explore 1 destination, including Florence. At the end of the day, you’ll unwind at one of the finest accommodations in Florence, where you'll spend 2 nights.

Embrace the thrill of the open road as you wave goodbye to Venice and set your GPS to Florence. While on the road, immerse yourself in your favorite road trip tunes or sample the sounds from a local radio station. This car ride usually takes around 2 hours 52 min. Upon reaching Florence, unwind, observe, and explore. The best things to do, see, and eat are waiting for you.

Pitti Palace is a notable palace we recommend visiting today. Discover its history-steeped features before continuing your self-guided tour to Ponte Vecchio, a visually striking historical landmark that’s well-regarded in the area.

Next, stop by Uffizi Gallery, a historic art gallery. While you’re nearby, don’t forget to visit Fountain Of Neptune, a visually striking and truly unique monument. End your sightseeing at Piazza Della Signoria, an extraordinary public square that’s highly recommended by travelers passing through the city.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Florence. Florence offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Florence. Enjoy a relaxing evening as you savor delicious local cuisine.

Enjoy a lovely meal at Ristorante Oliviero 1962, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Di Poneta Novoli is another top choice with a popular menu. You could also check for a table at Caffe San Firenze. As an establishment that consistently gains high praises from customers, it’s an ideal choice in Florence tonight.

After your meal, keep the night alive at a bar like Manifattura, known for its lively atmosphere. Se·sto On Arno Rooftop Bar is another top recommendation that provides the perfect setting with well-crafted drinks and a welcoming ambiance. Similarly, Il Vinile offers an excellent atmosphere for those looking to amp up the evening.

Raise your glass and celebrate another amazing day of your road trip in Italy!

Day 6 of your road trip will take you to the best attractions Florence has to offer. Cherish the 1 night you have left in the city and use the provided itinerary to discover what to see in Florence.

Piazzale Michelangelo makes a great addition to your morning plans. This spectacular observation deck is a symbolic place to see in Florence. Continue your discovery at Basilica Of Santa Croce In Florence, a culturally significant church with stories to tell.

As you stroll around Florence, take in the distinct atmosphere and learn what makes this city so unique. Maximize your sightseeing with a visit to Cathedral Of Santa Maria Del Fiore. This top-rated church offers an UNESCO world heritage-listed encounter with Florence. Next, make your way to Central Market to add another highlight to your day. After that, visit Galleria Dell'accademia, a well-known art gallery that’s sure to impress. If you’re up for more, end your self-guided sightseeing tour at David, a captivating statue in the city. Whether you decide to get entrance tickets for all attractions or you prefer admiring from a distance, amazing experiences await on this day in Florence.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

Florence is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Florence.

Dine in style at Ditta Artigianale, a top recommendation for dinner tonight. Or, for a change of pace, Trattoria Da Burde boasts a menu that's sure to impress. Also, be sure to check out Casa Toscana. Known as a local hotspot, it’s a great choice for tonight in Florence.

If you’re not ready to end the night just yet, Bar 50 Rosso offers a perfect venue to relax and savor a drink. Similarly, Bitter Bar is well-suited for those looking to unwind in a social setting. Archea Brewery is another excellent spot to enjoy a nightcap after a delightful meal.

Raise your glass to another unforgettable day in Italy!

On day 7 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, including Siena. When you’re not sightseeing, take time to relax at your chosen hotel in Siena, where you’ll be staying for 1 night.

Once you're ready to continue your road trip, it's time to buckle up and drive, eagerly anticipating your arrival in Siena. This drive usually takes around 1 hour 10 min, without any stops or traffic disruptions.

Spend your afternoon discovering Fortezza Medicea (siena), an intriguing monument known for its picture-perfect features. Next, continue your sightseeing at Basilica Of San Domenico, a locally appreciated church.

If you're starting to feel hungry, this is a great time for a break at a nearby restaurant or cafe. When you're ready for more, stop by Siena Cathedral and uncover the details of this inviting church. Make sure to also explore Piazza Del Campo, a widely recognized public square. For your last stop, consider Pubblico Palace, an UNESCO world heritage-designated palace that many travelers find worth the detour.

When you’re done exploring for the day, you’ll drive to your hotel in Siena. Check in and relax before you head out to tour the city.

Indulge in a memorable dining experience at one of Siena's most popular restaurants, and connect with friendly locals for a true cultural experience.

Make sure to reserve a table at Enoteca I Terzi, an iconic dining spot in Siena. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Ristorante Tar-Tufo, a popular restaurant in Siena. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Antica Trattoria Papei, a hidden gem nestled in Siena. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at Meet Life Cafè, a well-loved spot among locals and tourists. Or, head to Maudit Pub. This bar boasts a welcoming environment that is perfect for winding down. You could also continue your night at Bar Impero Siena, another top-rated place in the area.

Celebrate another amazing day of your road trip adventure in Italy!

Experience an unparalleled adventure on day 8 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 place, which are Rome. At the end of the day, you will retreat to the hotel of your choice in Rome, where will spend 2 nights.

Set your GPS to Rome and hit the road. Expect a journey of approximately 2 hours 42 min without stops. Soak in the beautiful landscapes as you drive and look forward to exploring your next destination. Rome beckons with new experiences!

Set out on a self-guided sightseeing tour at Colosseum and explore the UNESCO world heritage-listed features. Next, make your way to Roman Forum, another highlight in Rome. When you’re done exploring the archeological site, continue to Spanish Steps, a majestic public square.

Nearby, you will also find Piazza Di Spagna. This timeless public square is a top place to see in the area. Lastly, head to Trevi Fountain, a majestic monument that is perfect for some final exploring in the city.

At the end of the day, you will drive to Rome, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a day of adventure, treat yourself to an exquisite dinner at one of Rome's best restaurants.

Treat yourself to a wonderful meal at La Bottega Roma, a top-rated dining spot in Rome. If you're in the mood for something new, try Pasta In Corso, another premier location with a delectable menu. You might also want to book a table at Trattoria Vecchia Roma. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Rome.

To truly maximize your evening out, consider visiting La Botticella Of Poggi Giovanni after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to Almalu Trastevere, another bar with an inviting ambiance. Similarly, Bar Viminale Di Pepi Maurilio also offers a great atmosphere, ensuring a night filled with enjoyment and relaxation.

Relax and look forward to more memorable moments to come!

Wake up to day 9 of your road trip in Italy. On this day, you’ll embark on an exciting expedition discovering the enchanting sights and activities of Vatican City and Rome. With 1 night to stay in Rome, we encourage you to seize the day and discover the unexplored beauty of the city’s surroundings!

A visit to Trastevere is a must on the agenda today. This neighborhood is full of hidden gems and character, perfect for a leisurely stroll. Plus, you’ll be close to some of the city’s most famous sights.

Experience Pantheon, an iconic monument in the city. Then, head to Piazza Navona and soak in the ambiance of this detailed public square.

Vatican City welcomes you with a multitude of unique vacation experiences.

Next, continue your sightseeing at Sistine Chapel, a spectacular chapel.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Rome.

Rome is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Rome.

Treat yourself to a wonderful meal at RomAntica, a top-rated dining spot in Rome. If you're in the mood for something new, try Coso Ristorante, another premier location with a delectable menu. You might also want to book a table at DEROMA - Farine Romane. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Rome.

After your delicious meal, get a taste of the vibrant nightlife with a visit to Sant' Eustachio Caffè, known for its inviting atmosphere. Yellowsquare Rome is another great option if you’re looking for a place to get the night started. Similarly, Caffè Portofino provides a great setting to enjoy the night away.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in Italy.

Your itinerary for day 10 of your road trip in Italy includes 2 stops and features some of the highlights of Santa Maria degli Angeli and Valecchie. At the end of the day, enjoy the comforts of a top-rated hotel in Santa Maria degli Angeli, where you'll spend 1 night.

Santa Maria degli Angeli’s wonders await as you prepare for another journey on the road, leaving the breathtaking surroundings of Rome behind. This drive usually takes around 2 hours 22 min. Santa Maria degli Angeli welcomes you with a multitude of unique vacation experiences.

One of our top recommendations for your sightseeing is Mount Subasio. Spend some time admiring the serene features of the mountain range before you continue to your next stop. Then, head to Pinacoteca Comunale Palazzo Vallemani. This frequently visited art gallery is a traveler-favorite in the town.

If you're keen to see more, continue to Basilica Of San Francesco D'assisi. Feed your curiosity by learning something new about the church. Next, take your journey to Piazza Del Comune, an increasingly popular public square.

It’s time to gear up for the next part of your road trip adventure. Upon your arrival in Valecchie, you’ll be greeted with the opportunity to do some sightseeing and exploring.

Savor the day by heading to Chiesa Di San Pietro, a worthwhile church that draws visitors from near and far.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Santa Maria degli Angeli. Santa Maria degli Angeli offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Santa Maria degli Angeli. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Continue your lively evening at Bibenda Assisi Wine Tasting & Gourmet Food, Olive Oil And Chocolate Tastings, a perfect place for winding down or revving up the night, depending on which mood you’re in.

Head back to your accommodation in Santa Maria degli Angeli and get some rest to prepare for another magical day of your road trip in Italy.

On day 11 of your road trip in Italy, your travel plans include 1 stop at the most scenic, wondrous, and interesting places in the region. Bologna are on today's agenda. In the evening, you’ll end up in Trieste, where you will stay for 1 night.

When you’re ready to jump back into the car and say goodbye to Santa Maria degli Angeli, you’ll hit the road in the direction of Bologna. This drive usually takes around 3 hours 9 min.

When you're ready for some sights, head to Fountain Of Neptune, Bologna, an up-and-coming monument in Bologna. Explore its noteworthy features at your own pace before you continue your journey to your next attraction, Piazza Maggiore. This extraordinary public square is a top recommendation in the area.

When you’re ready to explore more, Piazza Santo Stefano is an excellent choice. Spend some time discovering what some claim to be the most romantic public square in the region. Next, continue your sightseeing at the well-known Two Towers and discover what makes this monument unique. If you’re up for one more stop in the city, head to San Martino, a photogenic church many travelers find the visit worthwhile.

When you’re done exploring for the day, you’ll drive to your hotel in Trieste. Check in and relax before you head out to tour the city.

Trieste is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Trieste.

Treat yourself to a delicious dinner at Caffè degli Specchi, an excellent option for tonight's dining. Looking for something different? Osteria Istriano Of Giobi And Oxa offers a tantalizing alternative with its diverse menu. And don’t miss Chimera di Bacco. Known for great service, it’s a fantastic choice for tonight in Trieste.

Extend your evening after a delightful meal by visiting "life" New Bar Torinese Snc, which offers the perfect atmosphere for a night out. Moreover, White Cafe is another popular option for a drink or two. Likewise, Café James Joyce also provides a great ambiance for reminiscing about the day and raising a toast to your vacation.

Take some time to reflect on your day and savor another beautiful night in Italy.