12-Day Italy Self-Drive Road Trip With Itinerary from Trieste to Venice, Florence, Siena, Rome, and Santa Maria degli Angeli

Wake up to day 2 of your extraordinary road trip in Italy. With 1 night left in Trieste, we encourage you to seize the day and discover the unexplored beauty of the city’s surroundings!

A blend of family-friendly attractions, romantic experiences, and breathtaking views await you in Trieste on today’s itinerary. First up is the well-known castle, Miramare Castle. Afterward, continue to Canale Ponterosso Trieste, a street every traveler should visit.

As you explore Trieste’s charming streets, take in the lively atmosphere and get to know the character of the village. Next, make your way to Palazzo Gopcevich. This intriguing palace is an essential stop. Following that, head to Molo Audace, another must-visit site that will enhance your experience. Don’t forget to stop by Piazza Unità D'italia, a popular public square in the village. Finally, end your day with a visit to Cattedrale Di San Giusto Martire, a historic church that offers the perfect conclusion to your sightseeing of the day.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Trieste.

After a day of adventure, treat yourself to an exquisite dinner at one of Trieste's best restaurants.

Make sure to reserve a table at Rustiko, an iconic dining spot in Trieste. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Caffè San Marco, a popular restaurant in Trieste. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Osteria Marise, a hidden gem nestled in Trieste. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

After savoring a delicious meal, step into the vibrant nightlife at Mast, where the evening is just getting started. In the same way, Urbanis offers a unique charm perfect for experiencing the local bar scene in Trieste. Coktail Bar Trieste | La Preferita is another top-recommended bar that is sure to get you into the mood for some dancing and celebrating.

Raise your glass and celebrate another amazing day of your road trip in Italy!

Dive into day 3 of your remarkable road trip in Italy. Today you will explore Venice, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Venice. You’ll stay here for 2 nights.

Bring your curiosity for today’s adventure around Trieste. Some of the city’s most loved attractions await! Bridge Of Sighs is the perfect place to start. This monument is one of the most locally renowned places to visit in Trieste. Next, head to Doge's Palace, a popular palace, known for its enchanting features.

In between the sights, don’t hesitate to take small detours to explore local stores and eateries. When you’re ready to continue your adventure, head to St Mark's Basilica. This enchanting church is a highly recommended experience. Nearby, you'll also find Piazza San Marco and Palazzo Contarini Del Bovolo. Visit these for an interesting touch to your journey. Finish the day with a visit to Rialto Bridge, a history-steeped historical landmark in Trieste.

At the end of the day, you will drive to Venice, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you explore more of Venice, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Savor the flavors at Bauer Hotel, a top pick for dinner tonight. Alternatively, L'Osteria Le Guglie beckons with its unique menu offerings. Also, consider Corner Pub. With its consistent customer satisfaction, it’s an excellent option for dining in Venice tonight.

Following your dinner, dive into the local bar culture at Al Parlamento. Enjoy this evening's relaxed ambiance with delightful drinks. Alternatively, go to The Caffe Rosso, the perfect place for those looking to experience the best of the nightlife. Similarly, Adagio provides excellent drinks and a great atmosphere, ensuring a memorable night out.

Savor another day of unforgettable experiences in Italy!

At the end of the day, you'll drive back to Venice, where you'll stay for 1 night more.

Cannaregio is a fantastic place you can explore today in Murano. This neighborhood is a testament to the city’s character, and it's easy to spend hours just walking around and admiring the surroundings. Soak in the Murano-way-of-life and visit all the nearby sights.

Today’s itinerary in Venice covers several incredible sights, including a lighthouse, a church, and an art gallery. Start your adventure at Murano Lighthouse. This locally appreciated lighthouse is a place that is appreciated by travelers and locals alike. Next, immerse yourself in the symbolic wonders of Santa Maria Gloriosa Dei Frari, a must-see church in the village.

Consider stopping for a small bite to eat or a drink at a local eatery to keep your energy going. When you’re ready, continue your discovery with a visit to Gallerie Dell'accademia. This curiosity-inducing art gallery offers an enriching experience. For a change of pace, head to Peggy Guggenheim Collection, where you can take in history-steeped features. Conclude your self-guided sightseeing tour with a visit to Santa Maria Della Salute. These sights offer a fulfilling end to a perfect day.

When you’re done exploring for the day, you’ll return to Venice and your accommodation.

Indulge in a memorable dining experience at one of Venice's most popular restaurants, and connect with friendly locals for an authentic adventure.

Make sure to reserve a table at Generator Venice, an iconic dining spot in Venice. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Nevodi, a popular restaurant in Venice. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Ristorante La Piazza, a hidden gem nestled in Venice. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Cap off your dinner by heading to Il Mercante, ideal for a leisurely evening with a drink in hand. The Irish Pub Venezia is another bar that offers an enjoyable setting. Similarly, Ai Stagneri is also a popular place to go on a night out, perfect for relaxing and socializing.

Say good night to Venice and look forward to another great day of your road trip in Italy!

On day 5 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Florence. In the evening, you’ll end up in Florence, where you will stay for 2 nights.

Get ready for an exciting day in Venice. Today’s sightseeing agenda includes a palace, a historical landmark, an art gallery, a monument, a public square and much more! Begin your adventure at Pitti Palace. This is a popular palace you should not miss. Another must-see is Ponte Vecchio, an iconic historical landmark in Venice.

When you’re ready for the next sight, head to Uffizi Gallery. From there, take a leisurely stroll to Fountain Of Neptune, another of the city’s intriguing attractions. We recommend continuing your self-guided tour at Piazza Della Signoria, a romantic place of interest in the city.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Florence. Florence offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Florence. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Enjoy a lovely dining experience at Ristorante Oliviero 1962, a popular restaurant in Florence. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Florence at Di Poneta Novoli, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated Caffe San Firenze. It’s yet another ideal choice to enhance your time in Florence tonight.

Let the evening flow smoothly from dinner to drinks at Manifattura, a top-rated bar in the area. For other recommendations, Se·sto On Arno Rooftop Bar provides a perfect setting for rounding out your night with style and great drinks. Likewise, Il Vinile offers a memorable night with diverse drink options and excellent service.

Head back to your accommodation in Florence and get some rest in preparation for another magical day of your road trip in Italy!

Day 6 of your road trip across Italy promises a magnificent time exploring Florence. You have 1 night left in Florence. Take the opportunity to experience more of the best attractions and activities in the city.

Bring your curiosity for today’s adventure around Florence. Some of the city’s most loved attractions await! Piazzale Michelangelo is the perfect place to start. This observation deck is one of the most extraordinary places to visit in Florence. Next, head to Basilica Of Santa Croce In Florence, a notable church, known for its culturally significant features.

In between the sights, don’t hesitate to take small detours to explore local stores and eateries. When you’re ready to continue your adventure, head to Cathedral Of Santa Maria Del Fiore. This romantic church is a highly recommended experience. Nearby, you'll also find Central Market and Galleria Dell'accademia. Visit these for an interesting touch to your journey.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Florence. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Don’t miss out on dining at Ditta Artigianale, a top-rated dining destination in Florence. If you're in the mood to try something new, consider Trattoria Da Burde, another top spot with a mouthwatering menu. You might also want to secure a reservation at Casa Toscana. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Florence this evening.

After enjoying a fulfilling meal, continue your evening at Bar 50 Rosso, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, Bitter Bar offers a welcoming atmosphere for easing into the nightlife. Similarly, Archea Brewery provides an excellent environment for a relaxed and enjoyable evening.

Take some time to reflect on your day and savor another beautiful night in Italy.

Experience an unparalleled adventure on day 7 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 vibrant destinations - Siena. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Siena. You will spend 1 night here for some well-deserved relaxation.

Florence is home to plenty of attractions that offer fun adventures, breathtaking views, and photo-friendly spots! Start at Fortezza Medicea (siena), an up-and-coming monument that is worthwhile a visit in the city. Nearby, you’ll find Basilica Of San Domenico, enchanting visitors with its breathtaking appeal. Continue your exploration at Siena Cathedral. This church is one of the city’s most captivating spots.

Enjoy the freedom of exploring Florence at your own pace and find hidden gems along the way. If you want to see more picture-perfect spots, make sure to visit Piazza Del Campo. After exploring the public square, head to the increasingly popular Pubblico Palace. Lastly, wrap up today’s self-guided sightseeing tour with a visit to Porta Pispini, a place of awe-inspiring interest in Florence.

When you’re done exploring for the day, you’ll drive to your hotel in Siena. Check in and spend some time relaxing before you head out to tour the city.

After a day of adventure, treat yourself to an exquisite dinner at one of Siena's best restaurants.

Dine in style at Enoteca I Terzi, a top recommendation for dinner tonight. Or, for a change of pace, Ristorante Tar-Tufo boasts a menu that's sure to impress. Also, be sure to check out Antica Trattoria Papei. Known as a local hotspot, it’s a great choice for tonight in Siena.

Keep the excitement of the evening going by visiting a bar or two. Meet Life Cafè is an excellent place to start. You could also check out Maudit Pub, offering a different kind of charm. A last recommendation for the day is Bar Impero Siena. This bar promises an enjoyable experience with tasty drinks and a vibrant setting.

Raise your glass and celebrate another amazing day of your road trip in Italy!

On day 8 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, Rome. When you’re not sightseeing, take time to relax at your selected hotel in Rome, where you’ll be staying for 2 nights.

Today's adventure in Siena promises more breathtaking discoveries and enriching experiences! Begin at Colosseum. This culturally significant archeological site is a highlight of any visit in the city. Then, enjoy Roman Forum, another culturally significant attraction that never fails to captivate visitors. Next, head over to Spanish Steps, one of the city’s most top-rated attractions, known for its grand features.

If you’re looking for more, spend time soaking in the atmosphere of Piazza Di Spagna. This enchanting public square is frequented by locals and tourists alike. To complete your memorable day, make sure to visit Trevi Fountain, a world-famous monument, and take a stroll around the area.

At the end of the day, you will drive to Rome, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Rome. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Enjoy a delicious meal at La Bottega Roma, a top-rated dining destination in Rome. If you're in the mood to try something new, consider Pasta In Corso, another top spot with a mouthwatering menu. You might also want to secure a reservation at Trattoria Vecchia Roma. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Rome this evening.

After your delicious meal, get a taste of the vibrant nightlife with a visit to La Botticella Of Poggi Giovanni, known for its inviting atmosphere. Almalu Trastevere is another great option if you’re looking for a place to get the night started. Similarly, Bar Viminale Di Pepi Maurilio provides a great setting to enjoy the night away.

Relax and reminisce about your day in Italy and look forward to more memorable moments to come!

On day 9 of your road trip, you’ll start and end your day in Rome, but spend part of the day exploring places of interest outside the immediate city. On today's itinerary, you'll find attractions in Vatican City and Rome. You still have 1 night left in Rome.

Trastevere is a neighborhood that stands out as one of the must-see places in Vatican City. Take a moment to explore its distinct atmosphere, and don’t miss the popular sightseeing spots just a short walk away.

Rome is home to plenty of attractions that offer fun adventures, photo-friendly spots, and historic treasures! Start at Vatican Museums, an iconic art museum that is worthwhile a visit in the city. Continue your exploration at St. Peter's Basilica. This major basilica is one of the city’s most timeless spots.

Enjoy the freedom of exploring Rome at your own pace and find hidden gems along the way. If you want to see more picture-perfect spots, make sure to visit Pantheon. After exploring the monument, head to the wondrous Piazza Navona.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Rome.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Rome. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Treat yourself to a delightful dinner at RomAntica, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Coso Ristorante? It's another excellent option with a diverse menu. Consider reserving a table at DEROMA - Farine Romane as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Rome.

Keep the evening going at Sant' Eustachio Caffè, a great choice for enjoying the after-dinner hours with a drink. You could also go to Yellowsquare Rome, which offers a similarly pleasant setting and great drinks. Another option is Caffè Portofino, which provides an inviting environment for unwinding after a busy day out.

Relax and reminisce about your day in Italy and look forward to more memorable moments to come!

Embark on another extraordinary experience on day 10 of your road trip in Italy. Today, you will make 2 stops and experience some of the highlights of Santa Maria degli Angeli and Valecchie. At the end of the day, you will enjoy the comforts of a top-rated hotel in Santa Maria degli Angeli, which will be your home away from home for 1 night.

Whether you prefer a leisurely exploration or a more fast-paced adventure, this itinerary in Rome allows for both. Start by heading to Mount Subasio. This locally appreciated mountain range provides an insightful glimpse into the town's identity. Next, discover Pinacoteca Comunale Palazzo Vallemani, a historic art gallery, promising a delightful encounter.

Continue your sightseeing with a visit to Basilica Of San Francesco D'assisi, a well-known church. When you’re done, don’t forget to make a stop at the often recommended Chiesa Di San Pietro. Round off your day at Piazza Del Comune, another gem in Rome with majestic features to discover.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Santa Maria degli Angeli. Santa Maria degli Angeli offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As dinnertime approaches, it's time to head out for a bite to eat in Santa Maria degli Angeli. If you are looking to dine at a popular restaurant in the town, it's often a good idea to reserve a table in advance.

Extend your evening after a delightful meal by visiting Bibenda Assisi Wine Tasting & Gourmet Food, Olive Oil And Chocolate Tastings, which offers the perfect atmosphere for a night out.

Celebrate another amazing day of your road trip adventure in Italy!

Dive into day 11 of your remarkable road trip in Italy. Today you will explore Bologna, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Trieste. You’ll stay here for 1 night.

Today’s itinerary in Santa Maria degli Angeli covers several incredible sights, including a monument, a public square, and a church. Start your adventure at Fountain Of Neptune, Bologna. This increasingly popular monument is a place that is appreciated by travelers and locals alike. Next, immerse yourself in the romantic wonders of Piazza Maggiore, a must-see public square in the city.

Consider stopping for a small bite to eat or a drink at a local eatery to keep your energy going. When you’re ready, continue your discovery with a visit to Piazza Santo Stefano. This curiosity-inducing public square offers an enriching experience. For a change of pace, head to Two Towers, where you can take in picture-perfect features. Conclude your self-guided sightseeing tour with a visit to San Martino. These sights offer a fulfilling end to a perfect day.

When you’re done exploring for the day, you’ll drive to your hotel in Trieste. Check in and spend some time relaxing before you head out to tour the city.

Indulge in a memorable dining experience at one of Trieste's most popular restaurants, and connect with friendly locals for an authentic adventure.

Treat yourself to a wonderful meal at Caffè degli Specchi, a top-rated dining spot in Trieste. If you're in the mood for something new, try Osteria Istriano Of Giobi And Oxa, another premier location with a delectable menu. You might also want to book a table at Chimera di Bacco. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Trieste.

After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at "life" New Bar Torinese Snc, a well-loved spot among locals and tourists. Or, head to White Cafe. This bar boasts a welcoming environment that is perfect for winding down. You could also continue your night at Café James Joyce, another top-rated place in the area.

Say good night to Trieste and look forward to another great day of your road trip in Italy!