12-Day Italy Self-Drive Road Trip With Itinerary from Venice traveling west to Verona, Milan, and Florence

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Explore the best of Italy on a remarkable 12-day road trip! Combine exploration with relaxation on a self-drive tour featuring Venice, Murano, Verona, Sirmione, Desenzano Del Garda, Peschiera del Garda, Milan, Florence, Siena, Pisa, and Bologna.

This perfectly planned road trip itinerary takes you through some of the best places to see in Italy. You will spend 3 nights in Venice, 2 nights in Verona, 2 nights in Milan, and 4 nights in Florence. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Venice, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Piazza San Marco and Rialto Bridge are just a couple of the bucket-list attractions that await your discovery.

As you hit the open road and drive through Venice, Murano, Verona, Sirmione, Desenzano Del Garda, Peschiera del Garda, Milan, Florence, Siena, Pisa, and Bologna, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.

Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!

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Driver’s age is 30 - 65
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Pick-up: 10:00
Drop-off: 10:00

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Customize tours under each day and destination

Day 1

Day 1

  • Venice - Arrival day
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  • Rialto Bridge
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Say hello to Venice! Your exciting road trip through Italy is just about to start. Navigating the top places to see in the region is a breeze with a car. The rental vehicle of your choice will be ready for pickup upon your arrival in the city. You will stay in Venice for 2 nights before you continue your adventure!

Venice is a beautiful city with plenty to discover. Taking a stroll in the city center is a great alternative. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

As afternoon approaches, head to your chosen hotel in Venice. Check-in typically starts around 2 to 4 PM at hotels in Italy. We recommend staying at a central location for easy access to key areas in the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Venice, it's often a good idea to reserve a table in advance.

Raise a toast to the start of your 12-day road trip in Italy!

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Day 2

Day 2

  • Venice
  • More

Drive 15 km, 39 min

  • Teatro La Fenice
  • Piazza San Marco
  • St Mark's Basilica
  • Doge's Palace
  • Bridge of Sighs
  • Murano
  • More

Wake up to day 2 of your road trip in Italy. On this day, you’ll embark on an exciting expedition discovering the enchanting sights and activities of Venice and Murano. With 1 night to stay in Venice, we encourage you to seize the day and discover the unexplored beauty of the city’s surroundings!

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Venice.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Venice. Enjoy a relaxing evening as you savor delicious local cuisine.

Relax and look forward to more memorable moments to come!

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Day 3

Day 3

  • Venice
  • Verona
  • More

Drive 119 km, 2 hours 7 min

  • Giusti Garden
  • Ponte Pietra
  • piazza delle Erbe
  • Verona Arena
  • Castelvecchio Museum
  • Castelvecchio Bridge
  • More

Experience an unparalleled adventure on day 3 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 place, which are Verona. At the end of the day, you will retreat to the hotel of your choice in Verona, where will spend 2 nights.

When you’re done exploring for the day, you’ll drive to your hotel in Verona. Check in and relax before you head out to tour the city.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Verona. Enjoy a satisfying meal that will recharge you for tonight's adventures.

As the sun sets, rest up and recharge for the next leg of your road trip in Italy.

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Day 4

Day 4

  • Verona
  • More

Drive 100 km, 2 hours 33 min

  • Archaeological site of Grotte di Catullo
  • Castello di Sirmione
  • Castello di Desenzano del Garda
  • Duomo di Santa Maria Maddalena
  • Villa Romana di Desenzano del Garda
  • Porta Brescia
  • More

On day 4 of your road trip, you’ll start and end your day in Verona, where you still have 1 night left. You'll spend part of the day exploring places of interest outside the immediate city, including Sirmione, Desenzano Del Garda, and Peschiera del Garda.

When you’re done exploring for the day, you’ll return to Verona and your accommodation.

After a day of adventure, treat yourself to an exquisite dinner at one of Verona's best restaurants.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in Italy.

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Day 5

Day 5

  • Verona
  • Milan
  • More

Drive 170 km, 2 hours 34 min

  • Castello Sforzesco
  • Pinacoteca di Brera
  • Duomo di Milano
  • Galleria Vittorio Emanuele II
  • More

On day 5 of your road trip in Italy, your travel plans include 1 stop at the most scenic, wondrous, and interesting places in the region. Milan are on today's agenda. In the evening, you’ll end up in Milan, where you will stay for 2 nights.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Milan. Milan offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

Milan is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Milan.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in Italy.

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Day 6

Day 6

  • Milan
  • More

Drive 275 km, 5 hours 39 min

  • I Giardini di Villa Melzi
  • Villa Carlotta
  • Orrido di Bellano
  • More

On day 6 of your road trip, you'll get the chance to experience Loppia and Rogaro. At the end of the day, you'll drive back to Milan, where you still have 1 night left to stay.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Milan.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Milan. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Raise your glass to another unforgettable day in Italy!

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Day 7

Day 7

  • Milan
  • Florence
  • More

Drive 306 km, 3 hours 32 min

  • Ponte Vecchio
  • Uffizi Gallery
  • Palazzo Vecchio
  • Loggia dei Lanzi
  • piazza della Signoria
  • More

Dive into day 7 of your remarkable road trip in Italy. Today you'll explore 1 destination, including Florence. At the end of the day, you’ll unwind at one of the finest accommodations in Florence, where you'll spend 4 nights.

At the end of the day, you will drive to Florence, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Florence, it's often a good idea to reserve a table in advance.

Relax and recharge in preparation for another adventurous day in Italy!

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Day 8

Day 8

  • Florence
  • More

Drive 6 km, 1 hour 32 min

  • piazzale Michelangelo
  • Basilica of Santa Croce in Florence
  • Cathedral of Santa Maria del Fiore
  • Central Market
  • Galleria dell'Accademia
  • David
  • More

You have 3 nights left in Florence. Take the opportunity to experience more of the best attractions and activities in the city.

Whether you decide to get entrance tickets for all attractions or you prefer admiring from a distance, amazing experiences await on this day in Florence.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Florence, it's often a good idea to reserve a table in advance.

Take some time to reflect on your day and savor another beautiful night in Italy.

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Day 9

Day 9

  • Florence
  • More

Drive 158 km, 2 hours 48 min

  • Porta Romana
  • Tower of Mangia
  • piazza del Campo
  • Siena Cathedral
  • Piazza del Duomo
  • Basilica of San Domenico
  • More

On day 9 of your road trip, you’ll start and end your day in Florence, where you have 2 nights left to stay.

When you’re done exploring for the day, you’ll return to Florence and your accommodation.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Florence, it's often a good idea to reserve a table in advance.

Celebrate another amazing day of your road trip adventure in Italy!

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Day 10

Day 10

  • Florence
  • More

Drive 198 km, 3 hours

  • Piazza del Duomo, Pisa
  • Campo santo
  • Pisa Cathedral
  • Angelo Caduto
  • Leaning Tower of Pisa
  • Knights' Square
  • More

Greet day 10 of your road trip in Italy with a smile and start your day with a hearty breakfast. You have 1 night to stay in Florence, so get ready to make the most of your time in the region. On the agenda for this day, you’ll find only the best things to see and do in Pisa.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Florence.

Florence is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Florence.

Raise your glass and celebrate another amazing day of your road trip in Italy!

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Day 11

Day 11

  • Florence
  • Venice
  • More

Drive 260 km, 3 hours 32 min

  • Portici di Bologna
  • Biblioteca comunale dell'Archiginnasio
  • Piazza Maggiore
  • Two Towers
  • Biblioteca Salaborsa
  • Bologna Cathedral
  • More

On day 11 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, including Bologna. When you’re not sightseeing, take time to relax at your chosen hotel in Venice, where you’ll be staying for 1 night.

When you’re done exploring for the day, you’ll drive to your hotel in Venice. Check in and relax before you head out to tour the city.

Indulge in a memorable dining experience at one of Venice's most popular restaurants, and connect with friendly locals for a true cultural experience.

Raise your glass to another unforgettable day in Italy!

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Day 12

Day 12

  • Venice - Departure day
  • More
  • Grand Canal
  • More

Day 12 of your road trip in Italy is your departure day. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!

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Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

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Your trip is protected, personalized, and priced right. No surprises, no stress.

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