13-Day Italy Self-Drive Road Trip With Itinerary from Brindisi to Lecce, Alberobello, Matera, Naples, Positano, and Rome
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Experience the freedom of the open road in Italy as you embark on an unforgettable 13-day road trip! This experience caters to every traveler, featuring destinations like Brindisi, Lecce, Alberobello, Matera, Pompei, Naples, Ottaviano, Sorrento, Vico Equense, Positano, Amalfi, Ravello, and Rome.
This perfectly planned road trip itinerary in Italy takes you through some of the best places to see in the country. You will spend 2 nights in Brindisi, 2 nights in Lecce, 1 night in Alberobello, 2 nights in Matera, 2 nights in Naples, 2 nights in Positano, and 1 night in Rome. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!
With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.
Upon arriving in Brindisi, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.
An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Trevi Fountain and Pantheon are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Piazza Navona, learn more about the unique St. Peter's Basilica, and immerse yourself in the vibrant atmosphere of Piazza Di Spagna.
As you hit the open road and drive through Brindisi, Lecce, Alberobello, Matera, Pompei, Naples, Ottaviano, Sorrento, Vico Equense, Positano, Amalfi, Ravello, and Rome, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.
Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.
This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.
The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!
Itinerary summary
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Day 1
- Brindisi - Arrival day
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- Colonne Romane
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Welcome to Brindisi, the perfect starting point for your road trip in Italy! Pick up your rental car and let the adventure begin. You will spend 1 night immersing yourself in Brindisi's charm before embarking on the next leg of your journey.
Brindisi is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out End Of The Via Appia Antica, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.
As afternoon approaches, head to your chosen hotel in Brindisi. Check-in typically starts around 2 to 4 PM at hotels in Italy. We recommend staying at a hotel in a central location for easy access to the best attractions, restaurants, and bars in the city.
As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Brindisi, it's often a good idea to reserve a table in advance.
Savor the flavors at Bracerie Escosazio, a top pick for dinner tonight. Alternatively, Penny beckons with its unique menu offerings. Also, consider Piadineria. With its consistent customer satisfaction, it’s an excellent option for dining in Brindisi tonight.
Round off your dining experience by visiting Peddy Bar. Pasticceria. Gelateria. Happyhour. Prodotti Celiaci. Slot Machines. Scommesse, a prime location for a drink. Alternatively, explore the distinctive characteristics of Eden Cafè, a bar catering to every mood and preference. Altair Cafè likewise offers a unique atmosphere, perfect for a memorable night out.
Raise a toast to the start of your 13-day road trip in Italy!
Day 2
- Brindisi
- Lecce
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Drive 40 km, 51 min
- Torrione dell'inferno
- Swabian Castle of Brindisi
- Giardini Pubblici Giuseppe Garibaldi - Villa Comunale
- Palazzo dei Celestini (Provincia di Lecce)
- Jewish Museum Lecce
- Basilica di Santa Croce
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On day 2 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Brindisi and Lecce. In the evening, you’ll end up in Lecce, where you will stay for 2 nights.
Start by visiting Torrione Dell'inferno, a prime spot to begin your journey. This symbolic monument is sure to impress. Next on your list is Swabian Castle Of Brindisi, another must-visit landmark and curiosity-inducing castle renowned for its awe-inspiring features.
While exploring and sightseeing, take time to savor the culture of Brindisi by sampling some local delicacies. When you’re ready for more sightseeing, head to Giardini Pubblici Giuseppe Garibaldi - Villa Comunale. This enchanting park is an essential place to visit for anyone looking for the full Brindisi experience. We also recommend visiting Palazzo Dei Celestini (provincia Di Lecce), an underrated palace. Nearby, you'll also find Jewish Museum Lecce, ready to add charm to your journey. End your self-guided sightseeing tour with a stop at Basilica Di Santa Croce and wrap up your day with its culturally significant appeal.
At the end of the day, you will drive to Lecce, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.
After a day of adventure, treat yourself to an exquisite dinner at one of Lecce's best restaurants.
Make sure to reserve a table at Alle due Corti, an iconic dining spot in Lecce. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Il Ristoro dei Templari Trattoria Pizzeria Braceria, a popular restaurant in Lecce. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of La Cucina di Mamma Elvira, a hidden gem nestled in Lecce. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.
If you’re not ready to end the night just yet, Sensi offers a perfect venue to relax and savor a drink. Similarly, Caffè Alvino is well-suited for those looking to unwind in a social setting. Jolly Roger is another excellent spot to enjoy a nightcap after a delightful meal.
Celebrate another amazing day of your road trip adventure in Italy!
Day 3
- Lecce
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Drive 2 km, 27 min
- Castello Carlo V
- Church of Saint Clare
- Museo Faggiano
- Gate of Saint Blaise
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On day 3 of your road trip, you will have an entire day to explore Lecce. You’ll stay in Lecce for 1 night and discover all the best things to see and do in the area.
Lecce is home to plenty of attractions that offer fun adventures, breathtaking views, and photo-friendly spots! Start at Castle Of Charles V, a locally appreciated castle that is worthwhile a visit in the city. Nearby, you’ll find Church Of Saint Clare, enchanting visitors with its inviting appeal. Continue your exploration at Museo Archeologico Faggiano. This museum is one of the city’s most often recommended spots.
Enjoy the freedom of exploring Lecce at your own pace and find hidden gems along the way. If you want to see more picture-perfect spots, make sure to visit Gate Of Saint Blaise.
Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.
After a day of adventure, treat yourself to an exquisite dinner at one of Lecce's best restaurants.
Treat yourself to a delightful dinner at Miro Coffee Bistrot & Lounge Bar, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Oscar Cafè? It's another excellent option with a diverse menu. Consider reserving a table at La Vecchia Osteria da Totu as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Lecce.
Explore the vibrant nightlife at Bar Il Palio after your meal, a hub for lively evenings and memorable moments. Or, head to Al Ventuno for a great selection of flavorful drinks and a charming setting. Furthermore, Avio is perfect for those looking to extend their night with a touch of local flavor.
Savor another day of unforgettable experiences in Italy!
Day 4
- Lecce
- Alberobello
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Drive 116 km, 1 hour 33 min
- Trullo Siamese monumento negozio souvenir
- Trulli di Alberobello Puglia
- Casa D'Amore
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On day 4 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, Alberobello. When you’re not sightseeing, take time to relax at your selected hotel in Alberobello, where you’ll be staying for 1 night.
Set out on a day brimming with fun adventures, picturesque spots, and historic treasures. Start at the beloved Trullo Siamese - Negozio Souvenirs, an UNESCO world heritage-designated gift shop in Lecce. Next, go to Trulli Di Alberobello Puglia.
After visiting Trullo Siamese - Negozio Souvenirs and Trulli Di Alberobello Puglia, have a stroll along Lecce's streets and take in the local charm. Continue your sightseeing by heading to Casa D'amore. This awe-inspiring historical landmark offers a unique experience.
When you’re done exploring for the day, you’ll drive to your hotel in Alberobello. Check in and spend some time relaxing before you head out to tour the town.
After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Alberobello. Enjoy a satisfying meal that will recharge you for tonight's adventures.
Enjoy a lovely dining experience at Ristorante "I Primi di Puglia" - Alberobello, a popular restaurant in Alberobello. This acclaimed establishment has earned the admiration of countless food lovers in the city.
Take some time to reflect on your day and savor another beautiful night in Italy.
Day 5
- Alberobello
- Matera
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Drive 96 km, 1 hour 41 min
- Parco Scultura La Palomba
- Crypt of Original Sin
- Palombaro lungo
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Dive into day 5 of your remarkable road trip in Italy. Today you will explore Matera, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Matera. You’ll stay here for 2 nights.
A blend of family-friendly attractions, scenic views, and picturesque spots await you in Alberobello on today’s itinerary. First up is the beloved sculpture garden, Parco Scultura La Palomba. Afterward, continue to Crypt Of Original Sin, a cave every traveler should visit.
As you explore Alberobello’s charming streets, take in the lively atmosphere and get to know the character of the city. Next, make your way to Palombaro Lungo. This underrated cave system is an essential stop.
After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Matera. Matera offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.
As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Matera. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.
Don’t miss out on dining at Ristorante Le Bubbole, a top-rated dining destination in Matera.
Raise your glass to another unforgettable day in Italy!
Day 6
- Matera
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Drive 2 km, 43 min
- Church of Saint Peter 'Barisano'
- Laboratory Museum of Rural Life
- Sassi di Matera
- Church of Saint Mary of Idris
- Casa Grotta del Casalnuovo
- Belvedere di Piazza Giovanni Pascoli
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Day 6 of your road trip across Italy promises a magnificent time exploring Matera. You have 1 night left in Matera. Take the opportunity to experience more of the best attractions and activities in the city.
Enjoy the perfect balance of relaxation and exploration in Matera today. One of the most curiosity-inducing attractions included on the itinerary is Church Of Saint Peter 'barisano'. This picture-perfect church will help you start your sightseeing on top. Then, take a leisurely stroll to Laboratory Museum Of Rural Life and learn what makes this history-steeped museum unique.
Throughout the day, make sure to take breaks to appreciate the surroundings. Next up, visit the notable Sassi Di Matera. After exploring the archeological site, head to Church Of Saint Mary Of Idris. This up-and-coming church is a highlight in Matera. As your day continues, stop by Casa Grotta Del Casalnuovo, known for its UNESCO world heritage-listed features. Lastly, don’t forget to check out the increasingly popular Belvedere Di Piazza Giovanni Pascoli. Enjoy exploring this incredible observation deck at your own pace.
Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.
As you explore more of Matera, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.
Have a fantastic dining experience at Baccanti, a highly recommended choice for tonight's dinner.
Take some time to reflect on your day and savor another beautiful night in Italy.
Day 7
- Matera
- Naples
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Drive 265 km, 3 hours 55 min
- Archaeological Park of Pompeii
- Basilica
- Castel Sant'Elmo
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Experience an unparalleled adventure on day 7 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 2 vibrant destinations - Pompei and Naples. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Naples. You will spend 2 nights here for some well-deserved relaxation.
Matera is home to plenty of attractions that offer family-friendly attractions, scenic views, and picturesque spots! Start at Archaeological Park Of Pompeii, a locally renowned archeological site that is worthwhile a visit in the town. Nearby, you’ll find Basilica, enchanting visitors with its UNESCO world heritage-designated appeal. Continue your exploration at Castel Sant'elmo. This castle is one of the town’s most interesting spots.
At the end of the day, you will drive to Naples, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.
Indulge in a memorable dining experience at one of Naples's most popular restaurants, and connect with friendly locals for an authentic adventure.
Treat yourself to a wonderful meal at L'Oca Nera Irish Pub, a top-rated dining spot in Naples. If you're in the mood for something new, try Mimì alla Ferrovia, another premier location with a delectable menu. You might also want to book a table at Spuzzulè Winebar. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Naples.
Continue your evening by exploring the vibrant nightlife scene at Happening Cocktail Bar, a prime destination for a thrilling night out. Also, don’t forget to check out Shanti Art Musik Bar, a bar that offers unique local touches. Likewise, Gran Caffè Gambrinus provides an excellent alternative for a fun evening.
As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in Italy.
Day 8
- Naples
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Drive 52 km, 1 hour 57 min
- Royal Palace of Naples
- Naples National Archaeological Museum
- Napoli Sotterranea Percorso Ufficiale
- Spaccanapoli
- Mount Vesuvius
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At the end of the day, you'll drive back to Naples, where you'll stay for 1 night more.
Naples is brimming with adventures. Today’s wonderful stops include a palace, a museum, a cave system, a street, a volcano and much more! Begin your sightseeing adventure at the frequently visited Royal Palace Of Naples and allow yourself time to explore. Just a short distance away you'll find your next stop, Naples National Archaeological Museum, a photogenic museum that draws visitors from far and near.
Continue your journey to Napoli Sotterranea Percorso Ufficiale, one of the city’s most popular spots that you shouldn’t miss. Another great site to visit is the locally appreciated Spaccanapoli. When you're finished at the street, Mount Vesuvius awaits your visit. This volcano is a visually striking highlight on today's itinerary.
When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Naples.
After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Naples. Enjoy a satisfying meal that will recharge you for tonight's adventures.
Don’t miss out on dining at Antica Pizzeria Di Matteo, a top-rated dining destination in Naples. If you're in the mood to try something new, consider Mercure Napoli Centro Angioino, another top spot with a mouthwatering menu. You might also want to secure a reservation at La Lazzara Trattoria e Pizzeria. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Naples this evening.
Unwind after your meal by stepping into Archivio Storico - Cocktail Bar & Wonderfood. This venue is celebrated for its extensive drink selections and cozy vibes. Alternatively, Archeobar offers a dynamic and energetic atmosphere for a glass or two. Don’t overlook Babette Pub, another top-rated bar in the area.
Head back to your accommodation in Naples and get some rest in preparation for another magical day of your road trip in Italy!
Day 9
- Naples
- Positano
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Drive 67 km, 1 hour 57 min
- Museo Correale di Terranova
- Viewpoint.8-Amalfi Dr
- Costiera Amalfitana Positano
- Spiaggia di Positano Marina Grande
- Chiesa di Santa Maria Assunta
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Embark on another extraordinary experience on day 9 of your road trip in Italy. Today, you will make 3 stops and experience some of the highlights of Sorrento, Vico Equense, and Positano. At the end of the day, you will enjoy the comforts of a top-rated hotel in Positano, which will be your home away from home for 2 nights.
Prepare for a day full of family-friendly attractions, scenic views, and picturesque spots. When you’re ready, kick off your sightseeing adventure at Museo Correale Di Terranova. This locally appreciated museum is a must-visit for anyone seeking a unique vacation experience. Another sight you shouldn’t miss is Viewpoint.8-amalfi Dr, one of the town’s best highlights.
Next, check out Costiera Amalfitana Positano, one of the most beloved places to see in Naples. This beach is a favorite among locals and travelers alike. Enjoy some downtime and refreshments before continuing to your next stop, Spiaggia Di Positano Marina Grande. Wander around and soak in the awe-inspiring atmosphere this beach offers. Then, head to Chiesa Di Santa Maria Assunta, a top-rated church that adds another dimension to your day.
When you’re done exploring for the day, you’ll drive to your hotel in Positano. Check in and spend some time relaxing before you head out to tour the village.
As dinnertime approaches, it's time to head out for a bite to eat in Positano. If you are looking to dine at a popular restaurant in the village, it's often a good idea to reserve a table in advance.
Savor the flavors at Terrazza Celè, a top pick for dinner tonight. Alternatively, Hotel Poseidon beckons with its unique menu offerings. Also, consider Hotel Villa Gabrisa. With its consistent customer satisfaction, it’s an excellent option for dining in Positano tonight.
Get a good night's sleep and look forward to another great day on the road in Italy!
Day 10
- Positano
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Drive 48 km, 2 hours
- Amalfi Coast
- Giardini Principessa di Piemonte
- Villa Rufolo
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On day 10 of your road trip, you’ll start and end your day in Positano, but spend part of the day exploring places of interest outside the immediate village. On today's itinerary, you'll find attractions in Amalfi and Ravello. You still have 1 night left in Positano.
Today’s route brings family-friendly attractions, romantic experiences, and scenic views. The first attraction of today is Amalfi Coast. Continue your discovery at Giardini Principessa Di Piemonte, a romantic park with stories to tell.
As you stroll around Positano, take in the distinct atmosphere and learn what makes this village so unique. Maximize your sightseeing with a visit to Villa Rufolo. This locally renowned historical landmark offers a visually striking encounter with Positano. Whether you decide to get entrance tickets for all attractions or you prefer admiring from a distance, amazing experiences await on this day in Positano.
When you’re done exploring for the day, you’ll return to Positano and your accommodation.
As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Positano. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.
Enjoy a delicious meal at Le Sirenuse, a highly-rated dining destination in Positano. If you're eager to try something different, consider Hotel Covo dei Saraceni, another top spot with a tantalizing menu. You might also want to secure a reservation at Da Vincenzo Positano 1958. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Positano this evening.
Relax and recharge in preparation for another adventurous day in Italy!
Day 11
- Positano
- Rome
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Drive 289 km, 4 hours 44 min
- Orange Garden
- Castel Sant'Angelo
- Piazza Navona
- Pantheon
- Trevi Fountain
- Piazza di Spagna
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On day 11 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Rome. In the evening, you’ll end up in Rome, where you will stay for 1 night.
Savor the day by visiting some of the best places to see in Positano, including a park, a castle, a public square, a monument and much more! Start your adventure at Orange Garden. This interesting park is a must-visit for travelers looking for a unique holiday experience. Make your way to Castel Sant'angelo located in Positano for another exciting encounter.
Next, immerse yourself in the setting of Piazza Navona. Its enchanting features will captivate you. After the public square, continue your tour of the city with a visit to Pantheon. Visitors usually appreciate the heritage-rich features of this monument. Next up is Trevi Fountain, a highly recommended monument. For a change of pace, head to Piazza Di Spagna. As one of the most world-famous attractions in Positano, this public square is the perfect place to end your self-guided sightseeing tour.
After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Rome. Rome offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.
As you explore more of Rome, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.
Treat yourself to a delicious dinner at La Bottega Roma, an excellent option for tonight's dining. Looking for something different? Pasta In Corso offers a tantalizing alternative with its diverse menu. And don’t miss Trattoria Vecchia Roma. With its reputation for pleasing customers, it’s a fantastic choice for tonight in Rome.
Keep the evening going at La Botticella Of Poggi Giovanni, a great choice for enjoying the after-dinner hours with a drink. You could also go to Almalu Trastevere, which offers a similarly pleasant setting and great drinks. Another option is Bar Viminale Di Pepi Maurilio, which provides an inviting environment for unwinding after a busy day out.
Say good night to Rome and look forward to another great day of your road trip in Italy!
Day 12
- Rome
- Brindisi
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Drive 581 km, 6 hours 17 min
- St Peter's Basilica
- The Last Judgment
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On day 12 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, Vatican City. When you’re not sightseeing, take time to relax at your selected hotel in Brindisi, where you’ll be staying for 1 night.
Start your adventure at St. Peter's Basilica. This wondrous major basilica is a place that is appreciated by travelers and locals alike.
These sights offer a fulfilling end to a perfect day.
At the end of the day, you will drive to Brindisi, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.
After a day of adventure, treat yourself to an exquisite dinner at one of Brindisi's best restaurants.
Have a fantastic dining experience at Betty - Gelateria Cafe Ristorante Pizzeria a Brindisi, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Bento offers an enticing alternative with its varied menu. Additionally, Cozza Nera is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Brindisi.
Raise your glass and celebrate another amazing day of your road trip in Italy!
Day 13
- Brindisi - Departure day
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- Saint Pietro of Schiavoni Archeologica Area
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Day 13 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Brindisi before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.
If you're up for some more sightseeing, we recommend visiting Saint Pietro Of Schiavoni Archeologica Area, a photogenic archeological site before you head out.
As your final day in Italy unfolds, enjoy a last-minute shopping spree in Brindisi's best shopping area. Enjoy finding the perfect gift or keepsake to remind you of your wonderful trip to Italy.
Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Brindisi.
If you're eager to try something different, consider Pizzeria La Nassa, another top spot with a tantalizing menu.
You’ll then say farewell to Brindisi. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!
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