13-Day Italy Self-Drive Road Trip With Itinerary from Florence traveling south to Siena, Perugia, Rome, Naples, and Amalfi

Day 2 of your road trip will take you to the best attractions Florence has to offer. Cherish the 2 nights you have left in the city and use the provided itinerary to discover what to see in Florence.

Galleria Dell'accademia is an ideal stop early in the day. This interesting art gallery is a must-visit in the city. When you’re ready for your next discovery, continue to Piazza Della Signoria, which may be one of the most visually striking places you will experience today.

One of the best things about exploring Florence on a self-guided tour is that you set the pace. There’s plenty of time for detours and discovering hidden gems. When you’re ready for your next stop, make your way to Ponte Vecchio, a wondrous historical landmark in the city. If you’re up for more discoveries, don’t forget to reserve some time for Uffizi Gallery and Basilica Of Santa Croce In Florence. End your day with a visit to Piazzale Michelangelo, a top-rated observation deck that’s sure to leave a lasting impression.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Florence, it's often a good idea to reserve a table in advance.

Enjoy a delicious meal at Ditta Artigianale, a highly-rated dining destination in Florence. If you're eager to try something different, consider Trattoria Da Burde, another top spot with a tantalizing menu. You might also want to secure a reservation at Casa Toscana. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Florence this evening.

Let the evening flow smoothly from dinner to drinks at Bar 50 Rosso, a top-rated bar in the area. For other recommendations, Bitter Bar provides a perfect setting for rounding out your night with style and great drinks. Likewise, Archea Brewery offers a memorable night with diverse drink options and excellent service.

Relax and recharge in preparation for another adventurous day in Italy!

On day 3 of your road trip, you’ll start and end your day in Florence, where you have 1 night left to stay.

Throughout the day, make sure to take breaks to appreciate the surroundings.

After soaking in Florence’s unique atmosphere, jump into the car with a full heart and drive in the direction of your next destination: Pisa. Expect your car journey to take a minimum of 1 hour 16 min. When you arrive in Pisa, it's time to take a break from the road.

When you're ready for some sights, head to Piazza Del Duomo, Pisa, a timeless public square in Pisa. Explore its historic features at your own pace before you continue your journey to your next attraction, Leaning Tower Of Pisa. This iconic monument is a top recommendation in the area.

Once you're ready to continue your road trip, it's time to buckle up and drive, eagerly anticipating your arrival in Lucca. This drive usually takes around 32 min, without any stops or traffic disruptions.

Enjoy sightseeing at your own pace and allow yourself time to explore the beautiful surroundings. Take your self-guided tour to Piazza Dell'anfiteatro, a locally renowned public square that everyone visiting Lucca should see. Next, head to Guinigi Tower. This visually striking monument is one of the most often recommended attractions in the region.

If you're keen to see more, don’t miss out on Mura Di Lucca, a visually striking historical landmark popular among locals as well as travelers.

When you’re done exploring for the day, you’ll return to Florence and your accommodation.

After a day of adventure, treat yourself to an exquisite dinner at one of Florence's best restaurants.

Treat yourself to a wonderful meal at Ristorante Buca Mario, a top-rated dining spot in Florence. If you're in the mood for something new, try Agricola Toscana, another premier location with a delectable menu. You might also want to book a table at Eataly Firenze. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Florence.

Keep the evening going at Gosh*, a great choice for enjoying the after-dinner hours with a drink. You could also go to Antico Caffè Del Moro - Art Bar Firenze, which offers a similarly pleasant setting and great drinks. Another option is Quelo Bar, which provides an inviting environment for unwinding after a busy day out.

Say good night to Florence and look forward to another great day of your road trip in Italy!

Dive into day 4 of your remarkable road trip in Italy. Today you'll explore 2 destinations, including Siena and San Gimignano. At the end of the day, you’ll unwind at one of the finest accommodations in Siena, where you'll spend 2 nights.

Once you're ready to continue your road trip, it's time to buckle up and drive, eagerly anticipating your arrival in Siena. This drive usually takes around 1 hour 12 min, without any stops or traffic disruptions.

Savor the day by heading to Siena Cathedral, a captivating church that draws visitors from near and far. When you're done, continue to Piazza Del Campo, where you can soak in the enchanting surroundings.

Next, explore Tower Of Mangia, yet another often recommended place to see in the area.

Fasten your seatbelt and make your way to your next stop — San Gimignano, home to many well-known sights in the region. Upon arrival in San Gimignano, we highly recommend checking out some of the top attractions.

Spend your afternoon discovering Chiesa Di Sant'agostino, an up-and-coming church known for its instagrammable features. Next, continue your sightseeing at Palazzo Comunale, Pinacoteca, Torre Grossa, a worthwhile museum.

If you're starting to feel hungry, this is a great time for a break at a nearby restaurant or cafe. When you're ready for more, stop by Piazza Del Duomo and uncover the details of this history-steeped public square.

When you’re done exploring for the day, you’ll drive to your hotel in Siena. Check in and relax before you head out to tour the city.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Siena. Enjoy a relaxing evening as you savor delicious local cuisine.

Dine in style at Enoteca I Terzi, a top recommendation for dinner tonight. Or, for a change of pace, Ristorante Tar-Tufo boasts a menu that's sure to impress. Also, be sure to check out Antica Trattoria Papei. Known as a local hotspot, it’s a great choice for tonight in Siena.

Continue the enjoyment post-dinner at Meet Life Cafè, a cherished local gathering spot renowned for its welcoming atmosphere. Similarly, Maudit Pub offers a vibrant space for indulging in well-crafted drinks and engaging conversation. You may also want to check out Bar Impero Siena. This bar is a favorite among both locals and visitors looking for a delightful evening out filled with laughter and fun.

Savor another day of unforgettable experiences in Italy!

On day 5 of your road trip in Italy, you’ll start and end your day in Siena, but spend the day exploring what’s beyond the city. Since you still have 1 night to spend in Siena, there’s no need to rush. Experience Pievasciata, San Regolo, Castellina in Chianti, and San Donato in Poggio to the fullest today with this curated day itinerary.

Whether you decide to explore Pievasciata on foot, use public transport, or join a guided tour, there are a few attractions you don’t want to miss.

When you’ve had your share of Siena, prepare for your next destination. Admire the views and listen to some good music as you drive in the direction of Pievasciata. Your travel time is around 26 min.

Parco Sculture Del Chianti is a curiosity-inducing sculpture garden we recommend visiting today. Discover its enchanting features before continuing your self-guided tour.

It’s time to gear up for the next part of your road trip adventure. Under favorable conditions, your drive to San Regolo may take around 21 min. Upon your arrival in San Regolo, you’ll be greeted with the opportunity to do some sightseeing and exploring.

For a more meaningful self-guided tour of the hamlet's best attractions, visit Castello Di Brolio, a frequently visited castle that is sure to impress. Take in the surroundings and enjoy the freedom of exploring at your own pace before you continue your journey.

Continue your road trip and head to your next destination, Castellina in Chianti. This car ride takes around 43 min.

For a more meaningful self-guided tour of the hamlet's best attractions, visit Rocca Di Castellina In Chianti, a worthwhile castle that is sure to impress. Take in the surroundings and enjoy the freedom of exploring at your own pace before you continue your journey.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Siena.

Siena is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Siena.

Enjoy a lovely meal at Osteria Quattro Venti, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Fischi per Fiaschi is another top choice with a popular menu. You could also check for a table at Osteria da Divo. As an establishment that consistently gains high praises from customers, it’s an ideal choice in Siena tonight.

Continue your evening by exploring the vibrant nightlife scene at Charlie Mixology Bar Di Aldinucci Riccardo, a prime destination for a thrilling night out. Also, don’t forget to check out Bar Pinacoteca, a bar that offers unique local touches. Likewise, San Paolo Pub provides an excellent alternative for a fun evening.

Raise your glass and celebrate another amazing day of your road trip in Italy!

On day 6 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 2 destinations, including Santa Maria degli Angeli and Perugia. When you’re not sightseeing, take time to relax at your chosen hotel in Perugia, where you’ll be staying for 1 night.

Set your GPS to Santa Maria degli Angeli and hit the road. Expect a journey of approximately 1 hour 39 min without stops. Soak in the beautiful landscapes as you drive and look forward to exploring your next destination. Santa Maria degli Angeli beckons with new experiences!

One of our top recommendations for your sightseeing is Chiesa Nuova Di San Francesco Convertito. Spend some time admiring the photogenic features of the church before you continue to your next stop. Then, head to Rocca Maggiore. This locally appreciated castle is a traveler-favorite in the town.

If you're keen to see more, continue to Basilica Of San Francesco D'assisi. Feed your curiosity by learning something new about the church.

When you’re ready to jump back into the car and say goodbye to Santa Maria degli Angeli, you’ll hit the road in the direction of Perugia. This drive usually takes around 27 min.

One of our top recommendations for your sightseeing is Rocca Paolina. Spend some time admiring the standout features of the historical landmark before you continue to your next stop. Then, head to Perugia Sotterranea Accesso. This curiosity-inducing cave system is a traveler-favorite in the town.

If you're keen to see more, continue to Piazza Iv Novembre. Feed your curiosity by learning something new about the public square.

At the end of the day, you will drive to Perugia, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a day of adventure, treat yourself to an exquisite dinner at one of Perugia's best restaurants.

Savor the flavors at Ristorante Settimo Sigillo, a top pick for dinner tonight. Alternatively, Caffè Baglioni beckons with its unique menu offerings. Also, consider Bar Pellas. With its consistent customer satisfaction, it’s an excellent option for dining in Perugia tonight.

To truly maximize your evening out, consider visiting Tommi Bar after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to Valentina, another bar with an inviting ambiance. Similarly, Caffe Dal Perugino also offers a great atmosphere, ensuring a night filled with enjoyment and relaxation.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in Italy.

Your itinerary for day 7 of your road trip in Italy includes 1 stop and features some of the highlights of Orvieto. At the end of the day, enjoy the comforts of a top-rated hotel in Rome, where you'll spend 3 nights.

As you explore Orvieto’s charming streets, take in the lively atmosphere and get to know the character of the town.

After soaking in Perugia’s unique atmosphere, jump into the car with a full heart and drive in the direction of your next destination: Orvieto. Expect your car journey to take a minimum of 1 hour 19 min. When you arrive in Orvieto, it's time to take a break from the road.

Set out on a self-guided sightseeing tour at Orvieto Cathedral and explore the inviting features. Next, make your way to Museo Dell'opera Del Duomo, another highlight in Orvieto. When you’re done exploring the museum, continue to Orvieto Underground, an instagrammable cave system.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Rome. Rome offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Rome, it's often a good idea to reserve a table in advance.

Make sure to reserve a table at La Bottega Roma, an iconic dining spot in Rome. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Pasta In Corso, a popular restaurant in Rome. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Trattoria Vecchia Roma, a hidden gem nestled in Rome. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Extend your evening after a delightful meal by visiting La Botticella Of Poggi Giovanni, which offers the perfect atmosphere for a night out. Moreover, Almalu Trastevere is another popular option for a drink or two. Likewise, Bar Viminale Di Pepi Maurilio also provides a great ambiance for reminiscing about the day and raising a toast to your vacation.

Get a good night's sleep and look forward to another great day on the road in Italy!

Wake up to day 8 of your road trip in Italy. On this day, you’ll embark on an exciting expedition discovering the enchanting sights and activities of Rome and Vatican City. With 2 nights to stay in Rome, we encourage you to seize the day and discover the unexplored beauty of the city’s surroundings!

Colosseum leaves a lasting impression. This archeological site is one of the most iconic places to visit in Rome. Next, head to Roman Forum, a timeless archeological site, known for its historic features.

In between the sights, don’t hesitate to take small detours to explore local stores and eateries. When you’re ready to continue your adventure, head to Trevi Fountain. This visually striking monument is a highly recommended experience. Nearby, you'll also find Pantheon and Piazza Navona Visit these for an interesting touch to your journey.

When you’ve had your share of Rome, prepare for your next destination. Admire the views and listen to some good music as you drive in the direction of Vatican City, Vatican City. Your travel time is around 12 min.

When you're ready for some sights, head to St. Peter's Basilica, a wondrous major basilica in Vatican City.

When you’re done exploring for the day, you’ll return to Rome and your accommodation.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Rome. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Make sure to reserve a table at RomAntica, an iconic dining spot in Rome. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Coso Ristorante, a popular restaurant in Rome. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of DEROMA - Farine Romane, a hidden gem nestled in Rome. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at Sant' Eustachio Caffè, a well-loved spot among locals and tourists. Or, head to Yellowsquare Rome. This bar boasts a welcoming environment that is perfect for winding down. You could also continue your night at Caffè Portofino, another top-rated place in the area.

Head back to your accommodation in Rome and get some rest to prepare for another magical day of your road trip in Italy.

On day 9 of your road trip, you'll get the chance to experience Tivoli. At the end of the day, you'll drive back to Rome, where you still have 1 night left to stay.

It’s time to gear up for the next part of your road trip adventure. Under favorable conditions, your drive to Tivoli may take around 38 min. Upon your arrival in Tivoli, you’ll be greeted with the opportunity to do some sightseeing and exploring.

Set out on a self-guided sightseeing tour at Hadrian's Villa and explore the breathtaking features. Next, make your way to Villa D'este, another highlight in Tivoli. When you’re done exploring the palace, continue to Fontana Dell'organo, an UNESCO world heritage-designated monument.

Nearby, you will also find Gregorian Bridge. This curiosity-inducing monument is a top place to see in the area. Lastly, head to Villa Gregoriana, a mesmerizing park that is perfect for some final exploring in the town.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Rome.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Rome. Enjoy a relaxing evening as you savor delicious local cuisine.

Treat yourself to a delicious dinner at Hotel de Russie, an excellent option for tonight's dining. Looking for something different? La Taverna Italiana offers a tantalizing alternative with its diverse menu. And don’t miss The Parrot Bar. Known for great service, it’s a fantastic choice for tonight in Rome.

Unwind after your meal by stepping into The Apartment Bar Roma. This venue is celebrated for its extensive drink selections and cozy vibes. Alternatively, Hotel Hassler Roma offers a dynamic and energetic atmosphere for a glass or two.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in Italy.

On day 10 of your road trip in Italy, your travel plans include 1 stop at the most scenic, wondrous, and interesting places in the region. Naples are on today's agenda. In the evening, you’ll end up in Naples, where you will stay for 1 night.

Fasten your seatbelt and make your way to your next stop — Naples, home to many well-known sights in the region. Keep in mind that your travel time from Rome to Naples may take around 2 hours 32 min without traffic disruptions. Upon arrival in Naples, we highly recommend checking out some of the top attractions.

When you're ready for some sights, head to Castel Sant'elmo, a popular castle in Naples. Explore its picture-perfect features at your own pace before you continue your journey to your next attraction, Naples National Archaeological Museum. This captivating museum is a top recommendation in the area.

When you’re ready to explore more, Cappella Sansevero is an excellent choice. Spend some time discovering what some claim to be the most noteworthy museum in the region. Next, continue your sightseeing at the worthwhile Spaccanapoli and discover what makes this street unique.

When you’re done exploring for the day, you’ll drive to your hotel in Naples. Check in and relax before you head out to tour the city.

Naples is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Naples.

Don’t miss out on dining at L'Oca Nera Irish Pub, a top-rated dining destination in Naples. If you're in the mood to try something new, consider Mimì alla Ferrovia, another top spot with a mouthwatering menu. You might also want to secure a reservation at Spuzzulè Winebar. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Naples this evening.

After savoring a delicious meal, step into the vibrant nightlife at Happening Cocktail Bar, where the evening is just getting started. In the same way, Shanti Art Musik Bar offers a unique charm perfect for experiencing the local bar scene in Naples. Gran Caffè Gambrinus is another top-recommended bar that is sure to get you into the mood for some dancing and celebrating.

Raise your glass to another unforgettable day in Italy!

Experience an unparalleled adventure on day 11 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 4 places, which are Ottaviano, Pompei, Ravello, and Amalfi. At the end of the day, you will retreat to the hotel of your choice in Amalfi, where will spend 1 night.

Continue your road trip and head to your next destination, Ottaviano. This car ride takes around 43 min.

Spend your afternoon discovering Mount Vesuvius, a locally appreciated volcano known for its picturesque features.

It’s time to gear up for the next part of your road trip adventure. Under favorable conditions, your drive to Pompei may take around 33 min. Upon your arrival in Pompei, you’ll be greeted with the opportunity to do some sightseeing and exploring.

Archaeological Park Of Pompeii is a popular archeological site we recommend visiting today. Discover its picture-perfect features before continuing your self-guided tour to Lupanare Di Pompei, a photogenic archeological site that’s well-regarded in the area.

After soaking in Pompei’s unique atmosphere, jump into the car with a full heart and drive in the direction of your next destination: Ravello. Expect your car journey to take a minimum of 51 min. When you arrive in Ravello, it's time to take a break from the road.

For a more meaningful self-guided tour of the city's best attractions, visit Villa Rufolo, a well-known historical landmark that is sure to impress. Take in the surroundings and enjoy the freedom of exploring at your own pace before you continue your journey.

At the end of the day, you will drive to Amalfi, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Amalfi. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Enjoy a delicious meal at Pasticceria Pansa Amalfi, a top-rated dining destination in Amalfi. If you're in the mood to try something new, consider Grand Hotel Excelsior Amalfi, another top spot with a mouthwatering menu. You might also want to secure a reservation at Lido Azzurro. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Amalfi this evening.

Round off your dining experience by visiting Bar Della Valle, a prime location for a drink.

As the sun sets, rest up and recharge for the next leg of your road trip in Italy.

Dive into day 12 of your remarkable road trip in Italy. Today you'll explore 1 destination, including Orvieto. At the end of the day, you’ll unwind at one of the finest accommodations in Florence, where you'll spend 1 night.

Embrace the thrill of the open road as you wave goodbye to Amalfi and set your GPS to Orvieto. While on the road, immerse yourself in your favorite road trip tunes or sample the sounds from a local radio station. This car ride usually takes around 4 hours 11 min. Upon reaching Orvieto, unwind, observe, and explore. The best things to do, see, and eat are waiting for you.

Well Of St. Patrick is a popular monument we recommend visiting today. Discover its picture-perfect features before continuing your self-guided tour.

Once you're ready to continue your road trip, it's time to buckle up and drive, eagerly anticipating your arrival in Orvieto. This drive usually takes around 4 hours 11 min, without any stops or traffic disruptions.

When you're ready for some sights, head to Torre Del Moro Orvieto, an up-and-coming monument in Orvieto. Explore its picture-perfect features at your own pace before you continue your journey to your next attraction, Pozzo Della Cava. This intriguing cave is a top recommendation in the area.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Florence. Florence offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

Indulge in a memorable dining experience at one of Florence's most popular restaurants, and connect with friendly locals for a true cultural experience.

Treat yourself to a delicious dinner at Tijuana, an excellent option for tonight's dining. Looking for something different? Djària - American Bar offers a tantalizing alternative with its diverse menu. And don’t miss The Florence Irish Pub. Known for great service, it’s a fantastic choice for tonight in Florence.

Say good night to Florence and look forward to another great day of your road trip in Italy!