13-Day Italy Self-Drive Road Trip With Itinerary from Florence traveling south to Siena, Perugia, Rome, Naples, and Amalfi

Day 2 of your road trip across Italy promises a magnificent time exploring Florence. You have 2 nights left in Florence. Take the opportunity to experience more of the best attractions and activities in the city.

A blend of fun adventures, photo-friendly spots, and historic treasures await you in Florence on today’s itinerary. First up is the captivating art gallery, Galleria Dell'accademia. Afterward, continue to Piazza Della Signoria, a public square every traveler should visit.

As you explore Florence’s charming streets, take in the lively atmosphere and get to know the character of the city. Next, make your way to Ponte Vecchio. This globally renowned historical landmark is an essential stop. Following that, head to Uffizi Gallery, another must-visit site that will enhance your experience. Don’t forget to stop by Basilica Of Santa Croce In Florence, a well-known church in the city. Finally, end your day with a visit to Piazzale Michelangelo, a grand observation deck that offers the perfect conclusion to your sightseeing of the day.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Florence. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Enjoy a lovely dining experience at Ditta Artigianale, a popular restaurant in Florence. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Florence at Trattoria Da Burde, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated Casa Toscana. It’s yet another ideal choice to enhance your time in Florence tonight.

Extend your evening after a delightful meal by visiting Bar 50 Rosso, which offers the perfect atmosphere for a night out. Moreover, Bitter Bar is another popular option for a drink or two. Likewise, Archea Brewery also provides a great ambiance for reminiscing about the day and raising a toast to your vacation.

Raise your glass and celebrate another amazing day of your road trip in Italy!

On day 3 of your road trip, you’ll start and end your day in Florence, where you'll stay for 1 night more.

A blend of fun adventures, scenic views, and picturesque spots await you in Florence on today’s itinerary. First up is the globally renowned public square, Piazza Del Duomo, Pisa. Afterward, continue to Leaning Tower Of Pisa, a monument every traveler should visit.

As you explore Florence’s charming streets, take in the lively atmosphere and get to know the character of the city. Next, make your way to Piazza Dell'anfiteatro. This popular public square is an essential stop. Following that, head to Guinigi Tower, another must-visit site that will enhance your experience. Don’t forget to stop by Mura Di Lucca, an often recommended historical landmark in the city.

When you’re done exploring for the day, you’ll return to Florence and your accommodation.

Indulge in a memorable dining experience at one of Florence's most popular restaurants, and connect with friendly locals for an authentic adventure.

Have a fantastic dining experience at Ristorante Buca Mario, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Agricola Toscana offers an enticing alternative with its varied menu. Additionally, Eataly Firenze is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Florence.

Keep the excitement of the evening going by visiting a bar or two. Gosh* is an excellent place to start. You could also check out Antico Caffè Del Moro - Art Bar Firenze, offering a different kind of charm. A last recommendation for the day is Quelo Bar. This bar promises an enjoyable experience with tasty drinks and a vibrant setting.

Celebrate another amazing day of your road trip adventure in Italy!

On day 4 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Siena and San Gimignano. In the evening, you’ll end up in Siena, where you will stay for 2 nights.

Enjoy the perfect balance of relaxation and exploration in Florence today. One of the most interesting attractions included on the itinerary is Siena Cathedral. This grand church will help you start your sightseeing on top. Then, take a leisurely stroll to Piazza Del Campo and learn what makes this UNESCO world heritage-listed public square unique.

Throughout the day, make sure to take breaks to appreciate the surroundings. Next up, visit the intriguing Tower Of Mangia. After exploring the monument, head to Chiesa Di Sant'agostino. This worthwhile church is a highlight in Florence. As your day continues, stop by Palazzo Comunale, Pinacoteca, Torre Grossa, known for its picture-perfect features. Lastly, don’t forget to check out the locally appreciated Piazza Del Duomo. Enjoy exploring this incredible public square at your own pace.

At the end of the day, you will drive to Siena, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you explore more of Siena, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Savor the flavors at Enoteca I Terzi, a top pick for dinner tonight. Alternatively, Ristorante Tar-Tufo beckons with its unique menu offerings. Also, consider Antica Trattoria Papei. With its consistent customer satisfaction, it’s an excellent option for dining in Siena tonight.

After your meal, keep the night alive at a bar like Meet Life Cafè, known for its lively atmosphere. Maudit Pub is another top recommendation that provides the perfect setting with well-crafted drinks and a welcoming ambiance. Similarly, Bar Impero Siena offers an excellent atmosphere for those looking to amp up the evening.

Get a good night's sleep and look forward to another great day on the road in Italy!

At the end of the day, you'll drive back to Siena, where you'll stay for 1 night more.

Today’s route brings family-friendly attractions, romantic experiences, and breathtaking views. The first attraction of today is Parco Sculture Del Chianti. This curiosity-inducing sculpture garden is a romantic place to see in Siena. Continue your discovery at Castello Di Brolio, a visually striking castle with stories to tell.

As you stroll around Siena, take in the distinct atmosphere and learn what makes this hamlet so unique. Maximize your sightseeing with a visit to Rocca Di Castellina In Chianti. This curiosity-inducing castle offers a romantic encounter with Siena. Next, make your way to Osservatorio Polifunzionale Del Chianti to add another highlight to your day. Whether you decide to get entrance tickets for all attractions or you prefer admiring from a distance, amazing experiences await on this day in Siena.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Siena.

As you explore more of Siena, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Dine in style at Osteria Quattro Venti, a top recommendation for dinner tonight. Or, for a change of pace, Fischi per Fiaschi boasts a menu that's sure to impress. Also, be sure to check out Osteria da Divo. Known as a local hotspot, it’s a great choice for tonight in Siena.

After enjoying a fulfilling meal, continue your evening at Charlie Mixology Bar Di Aldinucci Riccardo, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, Bar Pinacoteca offers a welcoming atmosphere for easing into the nightlife. Similarly, San Paolo Pub provides an excellent environment for a relaxed and enjoyable evening.

As the sun sets on another day of adventure, rest up and recharge for the next leg of your road trip in Italy.

Embark on another extraordinary experience on day 6 of your road trip in Italy. Today, you will make 2 stops and experience some of the highlights of Santa Maria degli Angeli and Perugia. At the end of the day, you will enjoy the comforts of a top-rated hotel in Perugia, which will be your home away from home for 1 night.

A blend of fun adventures, photo-friendly spots, and history-rich sites await you in Siena on today’s itinerary. First up is the worthwhile church, Chiesa Nuova Di San Francesco Convertito. Afterward, continue to Rocca Maggiore, a castle every traveler should visit.

As you explore Siena’s charming streets, take in the lively atmosphere and get to know the character of the town. Next, make your way to Basilica Of San Francesco D'assisi. This popular church is an essential stop. Following that, head to Rocca Paolina, another must-visit site that will enhance your experience. Don’t forget to stop by Perugia Sotterranea Accesso, a curiosity-inducing cave system in the town. Finally, end your day with a visit to Piazza Iv Novembre, an enchanting public square that offers the perfect conclusion to your sightseeing of the day.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Perugia. Perugia offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As dinnertime approaches, it's time to head out for a bite to eat in Perugia. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Treat yourself to a delicious dinner at Ristorante Settimo Sigillo, an excellent option for tonight's dining. Looking for something different? Caffè Baglioni offers a tantalizing alternative with its diverse menu. And don’t miss Bar Pellas. With its reputation for pleasing customers, it’s a fantastic choice for tonight in Perugia.

Keep the excitement of the evening going by visiting a bar or two. Tommi Bar is an excellent place to start. You could also check out Valentina, offering a different kind of charm. A last recommendation for the day is Caffe Dal Perugino. This bar promises an enjoyable experience with tasty drinks and a vibrant setting.

Take some time to reflect on your day and savor another beautiful night in Italy.

On day 7 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, Orvieto. When you’re not sightseeing, take time to relax at your selected hotel in Rome, where you’ll be staying for 3 nights.

Today's adventure in Perugia promises more breathtaking discoveries and enriching experiences! Begin at Orvieto Cathedral. This visually striking church is a highlight of any visit in the town. Then, enjoy Museo Dell'opera Del Duomo, another heritage-rich attraction that never fails to captivate visitors. Next, head over to Orvieto Underground, one of the town’s most locally appreciated attractions, known for its photogenic features.

When you’re done exploring for the day, you’ll drive to your hotel in Rome. Check in and spend some time relaxing before you head out to tour the city.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Rome. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Enjoy a lovely dining experience at La Bottega Roma, a popular restaurant in Rome. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Rome at Pasta In Corso, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated Trattoria Vecchia Roma. It’s yet another ideal choice to enhance your time in Rome tonight.

To truly maximize your evening out, consider visiting La Botticella Of Poggi Giovanni after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to Almalu Trastevere, another bar with an inviting ambiance. Similarly, Bar Viminale Di Pepi Maurilio also offers a great atmosphere, ensuring a night filled with enjoyment and relaxation.

Head back to your accommodation in Rome and get some rest in preparation for another magical day of your road trip in Italy!

Wake up to day 8 of your extraordinary road trip in Italy. With 2 nights left in Rome, we encourage you to seize the day and discover the unexplored beauty of the city’s surroundings!

Today’s well-planned self-sightseeing route offers several family-friendly attractions, scenic views, and picturesque spots. Whether you decide to explore Rome on foot, use public transport, or join a guided tour, there are a few attractions you don’t want to miss. Colosseum is the first of them. Spend some time admiring this breathtaking archeological site before continuing your journey. Roman Forum is your next stop. This wondrous archeological site is one of the best-rated sights in Rome.

Consider grabbing some lunch or a light snack to keep your energy going. Beyond the above-mentioned attractions, today is also the perfect time to visit Trevi Fountain. This enchanting monument is a sight to behold. To round off your sightseeing experience, visit Pantheon and Piazza Navona.

When you’re done exploring for the day, you’ll return to Rome and your accommodation.

After a day of adventure, treat yourself to an exquisite dinner at one of Rome's best restaurants.

Treat yourself to a wonderful meal at RomAntica, a top-rated dining spot in Rome. If you're in the mood for something new, try Coso Ristorante, another premier location with a delectable menu. You might also want to book a table at DEROMA - Farine Romane. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Rome.

After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at Sant' Eustachio Caffè, a well-loved spot among locals and tourists. Or, head to Yellowsquare Rome. This bar boasts a welcoming environment that is perfect for winding down. You could also continue your night at Caffè Portofino, another top-rated place in the area.

Head back to your accommodation in Rome and get some rest in preparation for another magical day of your road trip in Italy!

On day 9 of your road trip in Italy, you’ll start and end your day in Rome, but spend the day exploring what’s beyond the city. Since you will return to Rome for 1 night more, there’s no need to rush. Experience Tivoli to the fullest today with this curated day itinerary!

Get ready to discover some of the most iconic wonders in Rome, including an archeological site, a palace, a monument, a park, a waterfall and much more! Start your day at Hadrian's Villa. This breathtaking archeological site is a locally appreciated place to see in Rome. Then, wander over to Villa D'este. If respected sites excite you, this palace will be right up your alley. Nearby, you’ll also find Fontana Dell'organo. This history-steeped monument is a favorite among visitors.

Rome offers plenty to explore, ensuring every moment of your visit is filled with excitement and discovery. If you're up for more, Gregorian Bridge is an often recommended spot in the town that will captivate you with its unique charm. When you’re done at the monument, don’t forget to check out the mesmerizing Villa Gregoriana. Take a moment to appreciate the fascinating details of this intriguing park. Wrap up your self-guided tour of Rome's top attractions with a visit to Grande Cascata Di Tivoli.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Rome.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Rome. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Enjoy a lovely dining experience at Hotel de Russie, a popular restaurant in Rome. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Rome at La Taverna Italiana, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated The Parrot Bar. It’s yet another ideal choice to enhance your time in Rome tonight.

Let the evening flow smoothly from dinner to drinks at The Apartment Bar Roma, a top-rated bar in the area. For other recommendations, Hotel Hassler Roma provides a perfect setting for rounding out your night with style and great drinks.

Raise your glass to another unforgettable day in Italy!

Dive into day 10 of your remarkable road trip in Italy. Today you will explore Naples, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Naples. You’ll stay here for 1 night.

Today’s itinerary in Rome covers several incredible sights, including a castle, a museum, and a street. Start your adventure at Castel Sant'elmo. This well-known castle is a place that is appreciated by travelers and locals alike. Next, immerse yourself in the instagrammable wonders of Naples National Archaeological Museum, a must-see museum in the city.

Consider stopping for a small bite to eat or a drink at a local eatery to keep your energy going. When you’re ready, continue your discovery with a visit to Cappella Sansevero. This locally renowned museum offers an enriching experience. For a change of pace, head to Spaccanapoli, where you can take in history-steeped features. These sights offer a fulfilling end to a perfect day.

At the end of the day, you will drive to Naples, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

Indulge in a memorable dining experience at one of Naples's most popular restaurants, and connect with friendly locals for an authentic adventure.

Dine in style at L'Oca Nera Irish Pub, a top recommendation for dinner tonight. Or, for a change of pace, Mimì alla Ferrovia boasts a menu that's sure to impress. Also, be sure to check out Spuzzulè Winebar. Known as a local hotspot, it’s a great choice for tonight in Naples.

Continue your evening by exploring the vibrant nightlife scene at Happening Cocktail Bar, a prime destination for a thrilling night out. Also, don’t forget to check out Shanti Art Musik Bar, a bar that offers unique local touches. Likewise, Gran Caffè Gambrinus provides an excellent alternative for a fun evening.

Raise your glass to another unforgettable day in Italy!

Experience an unparalleled adventure on day 11 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 4 vibrant destinations - Ottaviano, Pompei, Ravello, and Amalfi. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Amalfi. You will spend 1 night here for some well-deserved relaxation.

Prepare for a day full of family-friendly attractions, natural wonders, and scenic views. When you’re ready, kick off your sightseeing adventure at Mount Vesuvius. This intriguing volcano is a must-visit for anyone seeking a unique vacation experience. Another sight you shouldn’t miss is Archaeological Park Of Pompeii, one of the city’s best highlights.

Next, check out Lupanare Di Pompei, one of the most beloved places to see in Naples. This archeological site is a favorite among locals and travelers alike. Enjoy some downtime and refreshments before continuing to your next stop, Villa Rufolo. Wander around and soak in the history-steeped atmosphere this historical landmark offers. Then, head to Amalfi Coast, a top-rated coast that adds another dimension to your day.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Amalfi. Amalfi offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Amalfi. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Have a fantastic dining experience at Pasticceria Pansa Amalfi, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Grand Hotel Excelsior Amalfi offers an enticing alternative with its varied menu. Additionally, Lido Azzurro is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Amalfi.

Round off your dining experience by visiting Bar Della Valle, a prime location for a drink.

Savor another day of unforgettable experiences in Italy!

On day 12 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Orvieto. In the evening, you’ll end up in Florence, where you will stay for 1 night.

Bring your curiosity for today’s adventure around Amalfi. Some of the village’s most loved attractions await! Well Of St. Patrick is the perfect place to start. This monument is one of the most locally renowned places to visit in Amalfi. Next, head to Torre Del Moro Orvieto, an intriguing monument, known for its awe-inspiring features.

In between the sights, don’t hesitate to take small detours to explore local stores and eateries. When you’re ready to continue your adventure, head to Pozzo Della Cava. This instagrammable cave is a highly recommended experience. Visit these for an interesting touch to your journey.

When you’re done exploring for the day, you’ll drive to your hotel in Florence. Check in and spend some time relaxing before you head out to tour the city.

After a day of adventure, treat yourself to an exquisite dinner at one of Florence's best restaurants.

Enjoy a lovely meal at Tijuana, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Djària - American Bar is another top choice with a popular menu. You could also check for a table at The Florence Irish Pub. As an establishment that gains consistently high praises from customers, it’s an ideal choice in Florence tonight.

Raise your glass and celebrate another amazing day of your road trip in Italy!