13-Day Italy Self-Drive Road Trip With Itinerary from Genoa traveling east to Florence, Rome, and Siena

On day 2 of your road trip, you’ll start and end your day in Genoa, but spend part of the day exploring places of interest outside the immediate city. On today's itinerary, you'll find attractions in Genoa and San Fruttuoso di Camogli. You still have 2 nights left in Genoa.

Today, you'll explore some of the most beautiful places in Genoa, including a monument, a public square, a church, a street, a palace, a nature reserve and much more! Start your day with a visit to Porta Soprana. This worthwhile monument is a must-visit in the city. When you’re ready for your next discovery, continue to Piazza De Ferrari, which may be one of the most visually striking places you will experience today.

One of the best things about exploring Genoa on a self-guided tour is that you set the pace. There’s plenty of time for detours and discovering hidden gems. When you’re ready for your next stop, make your way to Genoa Cathedral, an underrated church in the city. If you’re up for more discoveries, don’t forget to reserve some time for Via Garibaldi and Palazzo Podestà. End your day with a visit to Area Marina Protetta Di Portofino, a curiosity-inducing nature reserve that’s sure to leave a lasting impression.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Genoa.

As you explore more of Genoa, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Enjoy a lovely meal at Zeffirino, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Trattoria Vegia Zena is another top choice with a popular menu. You could also check for a table at Trattoria delle Grazie. As an establishment that gains consistently high praises from customers, it’s an ideal choice in Genoa tonight.

Say good night to Genoa and look forward to another great day of your road trip in Italy!

On day 3 of your road trip in Italy, you’ll start and end your day in Genoa, but spend the day exploring what’s beyond the city. Since you will return to Genoa for 1 night more, there’s no need to rush. Experience Riomaggiore, Manarola, and Corniglia to the fullest today with this curated day itinerary!

Prepare for a day full of fun adventures, scenic views, and photo-friendly spots. When you’re ready, kick off your sightseeing adventure at Riomaggiore. This underrated sightseeing destination is a must-visit for anyone seeking a unique vacation experience. Another sight you shouldn’t miss is Chiesa Di San Lorenzo, one of the village’s best highlights.

Next, check out Manarola Overlook Viewpoint, one of the most curiosity-inducing places to see in Genoa. This observation deck is a favorite among locals and travelers alike. Enjoy some downtime and refreshments before continuing to your next stop, Cinque Terre National Park. Wander around and soak in the UNESCO world heritage-designated atmosphere this national park offers.

When you’re done exploring for the day, you’ll return to Genoa and your accommodation.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Genoa. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Have a fantastic dining experience at Osteria Sant'Ilario, a highly recommended choice for tonight's dinner. If you're looking to mix things up, La Cialtroneria offers an enticing alternative with its varied menu. Additionally, Manhattan Bar is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Genoa.

Take some time to reflect on your day and savor another beautiful night in Italy.

Dive into day 4 of your remarkable road trip in Italy. Today you will explore Florence, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Florence. You’ll stay here for 3 nights.

Get ready for an exciting day in Genoa. Today’s sightseeing agenda includes a historical landmark, an art gallery, a palace, a public square and much more! Begin your adventure at Ponte Vecchio. This is a wondrous historical landmark you should not miss. Another must-see is Uffizi Gallery, an astonishing art gallery in Genoa.

When you’re ready for the next sight, head to Palazzo Vecchio. From there, take a leisurely stroll to Loggia Dei Lanzi, another of the city’s intriguing attractions. We recommend continuing your self-guided tour at Piazza Della Signoria, a visually striking place of interest in the city.

At the end of the day, you will drive to Florence, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a day of adventure, treat yourself to an exquisite dinner at one of Florence's best restaurants.

Dine in style at Ristorante Oliviero 1962, a top recommendation for dinner tonight. Or, for a change of pace, Di Poneta Novoli boasts a menu that's sure to impress. Also, be sure to check out Caffe San Firenze. Known as a local hotspot, it’s a great choice for tonight in Florence.

After your meal, keep the night alive at a bar like Manifattura, known for its lively atmosphere. Se·sto On Arno Rooftop Bar is another top recommendation that provides the perfect setting with well-crafted drinks and a welcoming ambiance. Similarly, Il Vinile offers an excellent atmosphere for those looking to amp up the evening.

Say good night to Florence and look forward to another great day of your road trip in Italy!

Day 5 offers a multitude of experiences. You will stay in Florence for 2 nights more, offering you enough time to explore at a relaxed pace.

A blend of fun adventures, picturesque spots, and historic treasures await you in Florence on today’s itinerary. First up is the notable statue, David. Afterward, continue to Galleria Dell'accademia, an art gallery every traveler should visit.

As you explore Florence’s charming streets, take in the lively atmosphere and get to know the character of the city. Next, make your way to Medici Chapels. This underrated museum is an essential stop. Following that, head to Cathedral Of Santa Maria Del Fiore, another must-visit site that will enhance your experience. Don’t forget to stop by Basilica Of Santa Croce In Florence, an interesting church in the city. Finally, end your day with a visit to Piazzale Michelangelo, a history-steeped observation deck that offers the perfect conclusion to your sightseeing of the day.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

As you explore more of Florence, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Treat yourself to a wonderful meal at Ditta Artigianale, a top-rated dining spot in Florence. If you're in the mood for something new, try Trattoria Da Burde, another premier location with a delectable menu. You might also want to book a table at Casa Toscana. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Florence.

Cap off your dinner by heading to Bar 50 Rosso, ideal for a leisurely evening with a drink in hand. Bitter Bar is another bar that offers an enjoyable setting. Similarly, Archea Brewery is also a popular place to go on a night out, perfect for relaxing and socializing.

Savor another day of unforgettable experiences in Italy!

Greet day 6 of your road trip in Italy with a smile and start your day with a hearty breakfast. You will return to Florence for your remaining 1 night in the city later today, but first, it’s time for some exploring! On the agenda for this day, you’ll find only the best things to see and do in Siena.

Florence is brimming with adventures. Today’s wonderful stops include a public square, a church, and a monument. Begin your sightseeing adventure at the underrated Piazza Del Duomo and allow yourself time to explore. Just a short distance away you'll find your next stop, Siena Cathedral, a history-steeped church that draws visitors from far and near.

Continue your journey to Piazza Del Campo, one of the city’s most famous spots that you shouldn’t miss. Another great site to visit is the locally appreciated Tower Of Mangia. When you're finished at the monument, Loggia Del Papa, Siena awaits your visit. This monument is a symbolic highlight on today's itinerary.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Florence.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Florence. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Enjoy a delicious meal at Ristorante Buca Mario, a highly-rated dining destination in Florence. If you're eager to try something different, consider Agricola Toscana, another top spot with a tantalizing menu. You might also want to secure a reservation at Eataly Firenze. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Florence this evening.

Unwind after your meal by stepping into Gosh*. This venue is celebrated for its extensive drink selections and cozy vibes. Alternatively, Antico Caffè Del Moro - Art Bar Firenze offers a dynamic and energetic atmosphere for a glass or two. Don’t overlook Quelo Bar, another top-rated bar in the area.

As the sun sets on another day of adventure, rest up and recharge for the next leg of your road trip in Italy.

On day 7 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, Rome. When you’re not sightseeing, take time to relax at your selected hotel in Rome, where you’ll be staying for 4 nights.

Whether you prefer a leisurely exploration or a more fast-paced adventure, this itinerary in Florence allows for both. Start by heading to Castel Sant'angelo. This famous castle provides an insightful glimpse into the city's identity. Next, discover Piazza Navona, a visually striking public square, promising a delightful encounter.

Continue your sightseeing with a visit to Pantheon, a timeless monument. When you’re done, don’t forget to make a stop at the timeless Trevi Fountain. Not far away from the monument, you will find the picture-perfect Circus Maximus, perfect for a quick visit. Round off your day at Piazza Del Popolo, another gem in Florence with visually striking features to discover.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Rome. Rome offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As you explore more of Rome, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Treat yourself to a delicious dinner at La Bottega Roma, an excellent option for tonight's dining. Looking for something different? Pasta In Corso offers a tantalizing alternative with its diverse menu. And don’t miss Trattoria Vecchia Roma. With its reputation for pleasing customers, it’s a fantastic choice for tonight in Rome.

Continue the enjoyment post-dinner at La Botticella Of Poggi Giovanni, a cherished local gathering spot renowned for its welcoming atmosphere. Similarly, Almalu Trastevere offers a vibrant space for indulging in well-crafted drinks and engaging conversation. You may also want to check out Bar Viminale Di Pepi Maurilio. This bar is a favorite among both locals and visitors looking for a delightful evening out filled with laughter and fun.

Raise your glass and celebrate another amazing day of your road trip in Italy!

Day 8 of your road trip will take you to the best attractions Rome has to offer. Cherish the 3 nights you have left in Rome by discovering the best things there are to see and do in the city.

Today’s itinerary in Rome covers several incredible sights, including an archeological site, a monument, a public square, a park and much more! Start your adventure at Colosseum. This globally renowned archeological site is a place that is appreciated by travelers and locals alike. Next, immerse yourself in the detailed wonders of Arch Of Constantine, a must-see monument in the city.

Consider stopping for a small bite to eat or a drink at a local eatery to keep your energy going. When you’re ready, continue your discovery with a visit to Roman Forum. This wondrous archeological site offers an enriching experience. For a change of pace, head to Piazza Di Spagna, where you can take in visually striking features. Conclude your self-guided sightseeing tour with a visit to Spanish Steps and Villa Borghese. These sights offer a fulfilling end to a perfect day.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Rome. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Enjoy a delicious meal at RomAntica, a top-rated dining destination in Rome. If you're in the mood to try something new, consider Coso Ristorante, another top spot with a mouthwatering menu. You might also want to secure a reservation at DEROMA - Farine Romane. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Rome this evening.

Continue your evening by exploring the vibrant nightlife scene at Sant' Eustachio Caffè, a prime destination for a thrilling night out. Also, don’t forget to check out Yellowsquare Rome, a bar that offers unique local touches. Likewise, Caffè Portofino provides an excellent alternative for a fun evening.

As the sun sets on another day of adventure, rest up and recharge for the next leg of your road trip in Italy.

On day 9 of your road trip, you’ll start and end your day in Rome, where you'll stay for 2 nights more.

Trastevere is a neighborhood that stands out as one of the must-see places in Vatican City. Take a moment to explore its distinct atmosphere, and don’t miss the popular sightseeing spots just a short walk away. For another highlight, head to Monti, a neighborhood offering its own unique experiences.

Today's adventure in Rome promises more breathtaking discoveries and enriching experiences! Begin at Vatican Museums.

When you’re done exploring for the day, you’ll return to Rome and your accommodation.

After a day of adventure, treat yourself to an exquisite dinner at one of Rome's best restaurants.

Dine in style at Hotel de Russie, a top recommendation for dinner tonight. Or, for a change of pace, La Taverna Italiana boasts a menu that's sure to impress. Also, be sure to check out The Parrot Bar. Known as a local hotspot, it’s a great choice for tonight in Rome.

Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, The Apartment Bar Roma stands out as an excellent choice for a post-dinner cocktail. Alternatively, Hotel Hassler Roma offers an ideal atmosphere to enjoy the pleasures of the night.

Raise your glass to another unforgettable day in Italy!

Wake up to day 10 of your extraordinary road trip in Italy. With 1 night left in Rome, we encourage you to seize the day and discover the unexplored beauty of the city’s surroundings!

Whether you prefer a leisurely exploration or a more fast-paced adventure, this itinerary in Rome allows for both. Start by heading to Piazza Del Plebiscito. This widely recognized public square provides an insightful glimpse into the city's identity. Next, discover Temple Of Venus, a stunning archeological site, promising a delightful encounter.

Continue your sightseeing with a visit to Archaeological Park Of Pompeii, a well-known archeological site.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Rome.

Indulge in a memorable dining experience at one of Rome's most popular restaurants, and connect with friendly locals for an authentic adventure.

Treat yourself to a wonderful meal at Sofitel Roma Villa Borghese, a top-rated dining spot in Rome. If you're in the mood for something new, try Centro, another premier location with a delectable menu. You might also want to book a table at Ristorante Tema. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Rome.

Head back to your accommodation in Rome and get some rest in preparation for another magical day of your road trip in Italy!

Embark on another extraordinary experience on day 11 of your road trip in Italy. Today, you will make 1 stop and experience some of the highlights of Siena. At the end of the day, you will enjoy the comforts of a top-rated hotel in Siena, which will be your home away from home for 1 night.

Rome is home to plenty of attractions that offer family-friendly attractions, breathtaking views, and picturesque spots! Start at Fortezza Medicea (siena), a beloved monument that is worthwhile a visit in the city. Nearby, you’ll find Basilica Of San Domenico, enchanting visitors with its historic appeal. Continue your exploration at Santuario Di Santa Caterina. This church is one of the city’s most worthwhile spots.

When you’re done exploring for the day, you’ll drive to your hotel in Siena. Check in and spend some time relaxing before you head out to tour the city.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Siena. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Make sure to reserve a table at Enoteca I Terzi, an iconic dining spot in Siena. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Ristorante Tar-Tufo, a popular restaurant in Siena. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Antica Trattoria Papei, a hidden gem nestled in Siena. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Keep the evening going at Meet Life Cafè, a great choice for enjoying the after-dinner hours with a drink. You could also go to Maudit Pub, which offers a similarly pleasant setting and great drinks. Another option is Bar Impero Siena, which provides an inviting environment for unwinding after a busy day out.

Celebrate another amazing day of your road trip adventure in Italy!

On day 12 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Pisa. In the evening, you’ll end up in Genoa, where you will stay for 1 night.

Immerse yourself in Siena’s rich culture with today's sightseeing itinerary. Start your journey at Leaning Tower Of Pisa. This picture-perfect monument is sure to ignite your curiosity. Next, dive into the breathtaking features of Pisa Cathedral, a must-visit church in the city.

In between sights, stop by local stores, picturesque photo spots, and small eateries. When you’re ready for your next attraction, proceed to Piazza Del Duomo, Pisa, an iconic public square. For a change of scene, check out Campo Santo, known for its culturally significant features.

At the end of the day, you will drive to Genoa, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As dinnertime approaches, it's time to head out for a bite to eat in Genoa. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Treat yourself to a wonderful meal at Vivarelli, a top-rated dining spot in Genoa. If you're in the mood for something new, try Trattoria Ugo, another premier location with a delectable menu. You might also want to book a table at TAZZE PAZZE Specialty Coffee. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Genoa.

Savor another day of unforgettable experiences in Italy!