13-Day Italy Self-Drive Road Trip With Itinerary from Genoa traveling east to Florence, Rome, and Siena

Greet day 2 of your road trip in Italy with a smile and start your day with a hearty breakfast. You have 2 nights to stay in Genoa, so get ready to make the most of your time in the region. On the agenda for this day, you’ll find only the best things to see and do in Genoa and San Fruttuoso di Camogli.

Whatever your travel style is, Porta Soprana is an essential stop in Genoa. This often recommended monument provides an insightful glimpse into the city's identity. Next, discover Piazza De Ferrari, a respected public square, promising a delightful encounter.

Continue your sightseeing with a visit to Genoa Cathedral, a worthwhile church. When you’re done, don’t forget to make a stop at the up-and-coming Via Garibaldi. Not far away from the street, you will find the serene Area Marina Protetta Di Portofino, perfect for a quick visit. Round off your day at Palazzo Podestà, another gem in Genoa with history-steeped features to discover.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Genoa.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Genoa. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Have a fantastic dining experience at Zeffirino, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Trattoria Vegia Zena offers an enticing alternative with its varied menu. Additionally, Trattoria delle Grazie is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Genoa.

Raise your glass and celebrate another amazing day of your road trip in Italy!

On day 3 of your road trip in Italy, you’ll start and end your day in Genoa, but spend the day exploring what’s beyond the city. Since you still have 1 night to spend in Genoa, there’s no need to rush. Experience Riomaggiore, Manarola, and Corniglia to the fullest today with this curated day itinerary.

One of the most intriguing attractions included on the itinerary is Riomaggiore. Then, take a leisurely stroll to Chiesa Di San Lorenzo and learn what makes this picture-perfect church unique.

Throughout the day, make sure to take breaks to appreciate the surroundings. Next up, visit the locally appreciated Manarola Overlook Viewpoint. After exploring the observation deck, head to Cinque Terre National Park. This captivating national park is a highlight in Genoa.

When you’re done exploring for the day, you’ll return to Genoa and your accommodation.

Genoa is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Genoa.

Treat yourself to a wonderful meal at Osteria Sant'Ilario, a top-rated dining spot in Genoa. If you're in the mood for something new, try La Cialtroneria, another premier location with a delectable menu. You might also want to book a table at Manhattan Bar. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Genoa.

Get a good night's sleep and look forward to another great day on the road in Italy!

On day 4 of your road trip in Italy, your travel plans include 1 stop at the most scenic, wondrous, and interesting places in the region. Florence are on today's agenda. In the evening, you’ll end up in Florence, where you will stay for 3 nights.

No visit to Genoa is complete without Ponte Vecchio. This globally renowned historical landmark is one of the top attractions in the city. Proceed to Uffizi Gallery, another must-visit attraction.

As you wander through the inviting streets of Genoa, soak in the lively ambiance and take the opportunity to snap some photos. Next, head to Palazzo Vecchio. This well-known palace is a traveler-favorite. Not far away, you’ll find Loggia Dei Lanzi, another key site on your sightseeing itinerary. Piazza Della Signoria is yet another highly recommended place to visit nearby, offering plenty to discover for curious travelers.

When you’re done exploring for the day, you’ll drive to your hotel in Florence. Check in and relax before you head out to tour the city.

Indulge in a memorable dining experience at one of Florence's most popular restaurants, and connect with friendly locals for a true cultural experience.

Have a fantastic dining experience at Ristorante Oliviero 1962, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Di Poneta Novoli offers an enticing alternative with its varied menu. Additionally, Caffe San Firenze is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Florence.

If you’re not ready to end the night just yet, Manifattura offers a perfect venue to relax and savor a drink. Similarly, Se·sto On Arno Rooftop Bar is well-suited for those looking to unwind in a social setting. Il Vinile is another excellent spot to enjoy a nightcap after a delightful meal.

Savor another day of unforgettable experiences in Italy!

Day 5 offers an itinerary packed with the best things to see in Florence. You’ll stay in Florence for 2 nights more, offering you enough time to explore at a relaxed pace.

Start your day at David. Then, wander over to Galleria Dell'accademia. If detailed sites excite you, this art gallery will be right up your alley. Nearby, you’ll also find Medici Chapels. This photogenic museum is a favorite among visitors.

Florence offers plenty to explore, ensuring every moment of your visit is filled with excitement and discovery. If you're up for more, Cathedral Of Santa Maria Del Fiore is a top-rated spot in the city that will captivate you with its unique charm. When you’re done at the church, don’t forget to check out the heritage-rich Basilica Of Santa Croce In Florence. Take a moment to appreciate the fascinating details of this popular church. Wrap up your self-guided tour of Florence's top attractions with a visit to Piazzale Michelangelo.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Florence. Enjoy a relaxing evening as you savor delicious local cuisine.

Make sure to reserve a table at Ditta Artigianale, an iconic dining spot in Florence. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Trattoria Da Burde, a popular restaurant in Florence. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Casa Toscana, a hidden gem nestled in Florence. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

After your delicious meal, get a taste of the vibrant nightlife with a visit to Bar 50 Rosso, known for its inviting atmosphere. Bitter Bar is another great option if you’re looking for a place to get the night started. Similarly, Archea Brewery provides a great setting to enjoy the night away.

Celebrate another amazing day of your road trip adventure in Italy!

On day 6 of your road trip, you'll get the chance to experience Siena. At the end of the day, you'll drive back to Florence, where you still have 1 night left to stay.

Whether you decide to explore Siena on foot, use public transport, or join a guided tour, there are a few attractions you don’t want to miss.

Awaiting your discovery is the frequently visited Piazza Del Duomo, an enchanting public square in Florence. Next, go to Siena Cathedral.

After visiting Piazza Del Duomo and Siena Cathedral, have a stroll along Florence's streets and take in the local charm. Continue your sightseeing by heading to Piazza Del Campo. This romantic public square offers a unique experience. Tower Of Mangia is another noteworthy attraction worthwhile a visit. End your self-guided sightseeing tour on top with a visit to Loggia Del Papa, Siena, one of the most instagrammable places to visit in Florence.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Florence.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Florence, it's often a good idea to reserve a table in advance.

Treat yourself to a delightful dinner at Ristorante Buca Mario, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Agricola Toscana? It's another excellent option with a diverse menu. Consider reserving a table at Eataly Firenze as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Florence.

Continue your evening by exploring the vibrant nightlife scene at Gosh*, a prime destination for a thrilling night out. Also, don’t forget to check out Antico Caffè Del Moro - Art Bar Firenze, a bar that offers unique local touches. Likewise, Quelo Bar provides an excellent alternative for a fun evening.

Relax and look forward to more memorable moments to come!

Dive into day 7 of your remarkable road trip in Italy. Today you'll explore 1 destination, including Rome. At the end of the day, you’ll unwind at one of the finest accommodations in Rome, where you'll spend 4 nights.

Castel Sant'angelo is perfect for a self-paced visit during the day. This symbolic castle is sure to impress. Next on your list is Piazza Navona, another must-visit landmark and world-famous public square renowned for its romantic features.

While exploring and sightseeing, take time to savor the culture of Florence by sampling some local delicacies. When you’re ready for more sightseeing, head to Pantheon. This culturally significant monument is an essential place to visit for anyone looking for the full Florence experience. We also recommend visiting Trevi Fountain, a wondrous monument. Nearby, you'll also find Piazza Del Popolo, ready to add charm to your journey. End your self-guided sightseeing tour with a stop at Circus Maximus and wrap up your day with its historic appeal.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Rome. Rome offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Rome. Enjoy a relaxing evening as you savor delicious local cuisine.

Savor the flavors at La Bottega Roma, a top pick for dinner tonight. Alternatively, Pasta In Corso beckons with its unique menu offerings. Also, consider Trattoria Vecchia Roma. With its consistent customer satisfaction, it’s an excellent option for dining in Rome tonight.

After enjoying a fulfilling meal, continue your evening at La Botticella Of Poggi Giovanni, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, Almalu Trastevere offers a welcoming atmosphere for easing into the nightlife. Similarly, Bar Viminale Di Pepi Maurilio provides an excellent environment for a relaxed and enjoyable evening.

Head back to your accommodation in Rome and get some rest to prepare for another magical day of your road trip in Italy.

Day 8 of your road trip across Italy promises a magnificent time exploring what to see in Rome. You have 3 nights left in Rome. Take the opportunity to experience more of the best attractions and activities in the city.

Whether you decide to explore Rome on foot, use public transport, or join a guided tour, there are a few attractions you don’t want to miss.

Look forward to a unique sightseeing adventure at the wondrous Colosseum and allow yourself time to explore. Just a short distance away you'll find your next stop, Arch Of Constantine, a culturally significant monument that draws visitors from far and near.

Continue your journey to Roman Forum, one of the city’s most timeless spots that you shouldn’t miss. Another great site to visit is the timeless Piazza Di Spagna. When you're finished at the public square, Spanish Steps awaits your visit. This public square is a history-steeped highlight on today's itinerary. Last up is a park - the spectacular Villa Borghese.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

Rome is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Rome.

Enjoy a lovely meal at RomAntica, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Coso Ristorante is another top choice with a popular menu. You could also check for a table at DEROMA - Farine Romane. As an establishment that consistently gains high praises from customers, it’s an ideal choice in Rome tonight.

Explore the vibrant nightlife at Sant' Eustachio Caffè after your meal, a hub for lively evenings and memorable moments. Or, head to Yellowsquare Rome for a great selection of flavorful drinks and a charming setting. Furthermore, Caffè Portofino is perfect for those looking to extend their night with a touch of local flavor.

Say good night to Rome and look forward to another great day of your road trip in Italy!

On day 9 of your road trip, you’ll start and end your day in Rome, where you still have 2 nights left. You'll spend part of the day exploring places of interest outside the immediate city, including Vatican City.

Trastevere is a fantastic place you can explore today in Vatican City. This neighborhood is a testament to the city’s character, and it's easy to spend hours just walking around and admiring the surroundings. Soak in the Vatican City-way-of-life and visit all the nearby sights. You should also check out Monti, a neighborhood offering more opportunities to enjoy the city’s vibrant atmosphere and landmarks.

Catch Vatican Museums before the crowds roll in.

In between sights, stop by local stores, picturesque photo spots, and small eateries. When you’re ready for your next attraction, proceed to St. Peter's Basilica, a wondrous major basilica.

When you’re done exploring for the day, you’ll return to Rome and your accommodation.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Rome. Enjoy a relaxing evening as you savor delicious local cuisine.

Enjoy a delicious meal at Hotel de Russie, a highly-rated dining destination in Rome. If you're eager to try something different, consider La Taverna Italiana, another top spot with a tantalizing menu. You might also want to secure a reservation at The Parrot Bar. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Rome this evening.

After enjoying a fulfilling meal, continue your evening at The Apartment Bar Roma, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, Hotel Hassler Roma offers a welcoming atmosphere for easing into the nightlife.

Say good night to Rome and look forward to another great day of your road trip in Italy!

Wake up to day 10 of your road trip in Italy. On this day, you’ll embark on an exciting expedition discovering the enchanting sights and activities of Naples and Pompei. With 1 night to stay in Rome, we encourage you to seize the day and discover the unexplored beauty of the city’s surroundings!

Piazza Del Plebiscito is an ideal stop early in the day. This widely recognized public square is a must-visit in the city. When you’re ready for your next discovery, continue to Temple Of Venus, which may be one of the most UNESCO world heritage-designated places you will experience today.

One of the best things about exploring Rome on a self-guided tour is that you set the pace. There’s plenty of time for detours and discovering hidden gems. When you’re ready for your next stop, make your way to Archaeological Park Of Pompeii, a captivating archeological site in the city.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Rome.

Indulge in a memorable dining experience at one of Rome's most popular restaurants, and connect with friendly locals for a true cultural experience.

Treat yourself to a delicious dinner at Sofitel Roma Villa Borghese, an excellent option for tonight's dining. Looking for something different? Centro offers a tantalizing alternative with its diverse menu. And don’t miss Ristorante Tema. Known for great service, it’s a fantastic choice for tonight in Rome.

Relax and recharge in preparation for another adventurous day in Italy!

Your itinerary for day 11 of your road trip in Italy includes 1 stop and features some of the highlights of Siena. At the end of the day, enjoy the comforts of a top-rated hotel in Siena, where you'll spend 1 night.

Fortezza Medicea (siena) brings Rome's character to life. This picture-perfect monument is a highlight of any visit in the city. Then, enjoy Basilica Of San Domenico, another historic attraction that never fails to captivate visitors. Next, head over to Santuario Di Santa Caterina, one of the city’s most curiosity-inducing attractions, known for its heritage-rich features.

At the end of the day, you will drive to Siena, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Siena, it's often a good idea to reserve a table in advance.

Enjoy a delicious meal at Enoteca I Terzi, a top-rated dining destination in Siena. If you're in the mood to try something new, consider Ristorante Tar-Tufo, another top spot with a mouthwatering menu. You might also want to secure a reservation at Antica Trattoria Papei. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Siena this evening.

Continue your lively evening at Meet Life Cafè, a perfect place for winding down or revving up the night, depending on which mood you’re in. Maudit Pub is another excellent bar that offers a great selection of drinks to suit any mood. If you prefer to go somewhere else, Bar Impero Siena ensures a night out tailored to your taste.

Relax and recharge in preparation for another adventurous day in Italy!

Experience an unparalleled adventure on day 12 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 place, which are Pisa. At the end of the day, you will retreat to the hotel of your choice in Genoa, where will spend 1 night.

Leaning Tower Of Pisa is must-visit monument and a great option for a daytime tour of the area. Continue your journey to Pisa Cathedral, a curiosity-inducing church, located just a leisurely stroll away. Next, head to Piazza Del Duomo, Pisa, a stunning public square, also available for your discovery today.

When you’re done exploring for the day, you’ll drive to your hotel in Genoa. Check in and relax before you head out to tour the city.

After a day of adventure, treat yourself to an exquisite dinner at one of Genoa's best restaurants.

Don’t miss out on dining at Vivarelli, a top-rated dining destination in Genoa. If you're in the mood to try something new, consider Trattoria Ugo, another top spot with a mouthwatering menu. You might also want to secure a reservation at TAZZE PAZZE Specialty Coffee. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Genoa this evening.

Take some time to reflect on your day and savor another beautiful night in Italy.