13-Day Italy Self-Drive Road Trip With Itinerary from Pisa traveling south to Arezzo, Rome, Salerno, Naples, L'aquila, Perugia, and Florence

Dive into day 2 of your remarkable road trip in Italy. Today you'll explore 2 destinations, including Pisa and Tirrenia. At the end of the day, you’ll unwind at one of the finest accommodations in Arezzo, where you'll spend 1 night.

Let Leaning Tower Of Pisa set the tone for the day. Spend some time admiring this breathtaking monument before continuing your journey. Piazza Del Duomo, Pisa is your next stop. This globally renowned public square is one of the best-rated sights in Pisa.

Consider grabbing some lunch or a light snack to keep your energy going. Beyond the above-mentioned attractions, today is also the perfect time to visit Pisa Cathedral. This UNESCO world heritage-designated church is a sight to behold.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Arezzo. Arezzo offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

Arezzo is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Arezzo.

Start your culinary exploration in Arezzo by securing a reservation at Octavin. This renowned restaurant holds 1 Michelin star and offers an exceptional menu of creative cuisine. Immerse yourself in the culinary delights of La Clandestina, a popular restaurant in Arezzo. With a menu designed to delight, it ensures a dining experience that transcends the ordinary.

Continue the enjoyment post-dinner at Liquid Bar, a cherished local gathering spot renowned for its welcoming atmosphere.

Celebrate another amazing day of your road trip adventure in Italy!

On day 3 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, including Vatican City. When you’re not sightseeing, take time to relax at your chosen hotel in Rome, where you’ll be staying for 3 nights.

Once you're ready to continue your road trip, it's time to buckle up and drive towards Vatican City, eagerly anticipating your arrival in Vatican City. This drive usually takes around 2 hours 32 min, without any stops or traffic disruptions.

Savor the day by heading to Vatican Museums, a wondrous art museum that draws visitors from near and far.

Next, explore Saint Peter's Square, yet another interesting place to see in the area. After the square, make time to go to St. Peter's Basilica.

At the end of the day, you will drive to Rome, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Rome, it's often a good idea to reserve a table in advance.

Dive into a culinary adventure like no other in Rome by booking a table at La Pergola. This popular restaurant holds 3 Michelin star and offers an exceptional menu of mediterranean and contemporary cuisine. For another dining option, venture to Il Pagliaccio, celebrated for its delectable creative and innovative menu. This acclaimed 2-star Michelin-recipient consistently leaves guests satisfied, ensuring an essential addition to your holiday itinerary. Seeking an alternative? Discover Enoteca La Torre, a top local restaurant known for its tantalizing mediterranean and creative menu. With a 2-star Michelin recognition, it promises an exceptional dining experience not to be missed.

Continue your evening by exploring the vibrant nightlife scene at La Botticella Of Poggi Giovanni, a prime destination for a thrilling night out. Also, don’t forget to check out Almalu Trastevere, a bar that offers unique local touches. Likewise, Bar Viminale Di Pepi Maurilio provides an excellent alternative for a fun evening.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in Italy.

Day 4 of your road trip across Italy promises a magnificent time exploring what to see in Rome. You have 2 nights left in Rome. Take the opportunity to experience more of the best attractions and activities in the city.

Campo De' Fiori is must-visit public square and a great option for a daytime tour of the area. Continue your journey to Piazza Navona, a wondrous public square, located just a leisurely stroll away. Next, head to Pantheon, a photogenic monument, also available for your discovery today.

Each stop on today’s itinerary promises to leave you with lasting memories and a deeper appreciation for Rome. When you're ready, let your sightseeing route take you to the globally renowned Roman Forum. If you’re looking for more, Colosseum is also a wondrous attraction that is worthwhile a visit.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

Rome is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Rome.

Enjoy a lovely dining experience at RomAntica, a popular restaurant in Rome. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Rome at Coso Ristorante, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated DEROMA - Farine Romane. It’s yet another ideal choice to enhance your time in Rome tonight.

Extend your evening after a delightful meal by visiting Sant' Eustachio Caffè, which offers the perfect atmosphere for a night out. Moreover, Yellowsquare Rome is another popular option for a drink or two. Likewise, Caffè Portofino also provides a great ambiance for reminiscing about the day and raising a toast to your vacation.

Relax and look forward to more memorable moments to come!

On day 5 of your road trip, you will have an entire day to discover what to see in Rome. You’ll stay in Rome for 1 night.

Rome is brimming with adventures.

Visiting Spanish Steps is always a good idea. This astonishing public square is a place that is appreciated by travelers and locals alike. Next, immerse yourself in the history-steeped wonders of Piazza Di Spagna, a must-see public square in the city.

Consider stopping for a small bite to eat or a drink at a local eatery to keep your energy going. When you’re ready, continue your discovery with a visit to Trevi Fountain. This timeless monument offers an enriching experience. For a change of pace, head to Basilica Di Santa Maria Maggiore, where you can take in UNESCO world heritage-listed features. Conclude your self-guided sightseeing tour with a visit to Circus Maximus These sights offer a fulfilling end to a perfect day.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

After a day of adventure, treat yourself to an exquisite dinner at one of Rome's best restaurants.

Enjoy a delicious meal at Hotel de Russie, a highly-rated dining destination in Rome. If you're eager to try something different, consider La Taverna Italiana, another top spot with a tantalizing menu. You might also want to secure a reservation at The Parrot Bar. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Rome this evening.

Unwind after your meal by stepping into The Apartment Bar Roma. This venue is celebrated for its extensive drink selections and cozy vibes. Alternatively, Hotel Hassler Roma offers a dynamic and energetic atmosphere for a glass or two.

Relax and recharge in preparation for another adventurous day in Italy!

On day 6 of your road trip in Italy, your travel plans include 1 stop at the most scenic, wondrous, and interesting places in the region. Rome are on today's agenda. In the evening, you’ll end up in Salerno, where you will stay for 1 night.

Altare Della Patria is an ideal stop early in the day. This interesting monument is a must-visit in the city. When you’re ready for your next discovery, continue to Castel Sant'angelo, which may be one of the most symbolic places you will experience today.

One of the best things about exploring Rome on a self-guided tour is that you set the pace. There’s plenty of time for detours and discovering hidden gems. When you’re ready for your next stop, make your way to Piazza Del Popolo, a top-rated public square in the city. If you’re up for more discoveries, don’t forget to reserve some time for Passeggiata Del Pincio and Villa Borghese.

When you’re done exploring for the day, you’ll drive to your hotel in Salerno. Check in and relax before you head out to tour the city.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Salerno. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Get ready for an unforgettable culinary journey in Salerno by reserving a table at Re Maurì. Renowned as a 1-star Michelin restaurant, it offers an exceptional creative menu. If you're in the mood to try something new, consider L'Unico Drink & Food Salerno, another top spot with a mouthwatering menu.

Round off your dining experience by visiting Hilton Bar E Gastronomia, a prime location for a drink. Alternatively, explore the distinctive characteristics of The Black Monday Speakeasy Tbm, a bar catering to every mood and preference. Dòmo I' Vinaino Wine Bar - Enogastronomia likewise offers a unique atmosphere, perfect for a memorable night out.

Head back to your accommodation in Salerno and get some rest to prepare for another magical day of your road trip in Italy.

Experience an unparalleled adventure on day 7 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 3 places, which are Amalfi, Ravello, and Pompei. At the end of the day, you will retreat to the hotel of your choice in Naples, where will spend 2 nights.

When you’ve had your share of Salerno, prepare for your next destination. Admire the views and listen to some good music as you drive in the direction of Amalfi. Your travel time is around 57 min.

Amalfi Coast is a famous coast we recommend visiting today.

Continue your road trip and head to your next destination, Ravello. This car ride takes around 19 min.

Savor the day by heading to Villa Rufolo, a well-known historical landmark that draws visitors from near and far.

Embrace the thrill of the open road as you wave goodbye to Ravello and set your GPS to Pompei. While on the road, immerse yourself in your favorite road trip tunes or sample the sounds from a local radio station. This car ride usually takes around 47 min. Upon reaching Pompei, unwind, observe, and explore. The best things to do, see, and eat are waiting for you.

Set out on a self-guided sightseeing tour at Archaeological Park Of Pompeii and explore the instagrammable features. Next, make your way to Teatro Grande, another highlight in Pompei. When you’re done exploring the archeological site, continue to Amphitheatre Of Pompeii, a picture-perfect archeological site.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Naples. Naples offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

Indulge in a memorable dining experience at one of Naples's most popular restaurants, and connect with friendly locals for a true cultural experience.

Enjoy an outstanding dining experience at Veritas, a 1-star Michelin restaurant offering an exceptional campanian and contemporary menu. Alternatively, if you're in the mood for something different, consider the nearby 1-star Michelin-awardee, Il Comandante, known for its delicious creative and mediterranean cuisine. Another highly-recommended place to eat in Naples is ARIA, a renowned restaurant with a 1-star Guide Michelin recognition and a delicious contemporary and modern menu.

Keep the excitement of the evening going by visiting a bar or two. Happening Cocktail Bar is an excellent place to start. You could also check out Shanti Art Musik Bar, offering a different kind of charm. A last recommendation for the day is Gran Caffè Gambrinus. This bar promises an enjoyable experience with tasty drinks and a vibrant setting.

Raise your glass to another unforgettable day in Italy!

Day 8 of your road trip will take you to the best attractions Naples has to offer. Cherish the 1 night you have left in the city and use the provided itinerary to discover what to see in Naples.

Whether you decide to explore Naples on foot, use public transport, or join a guided tour, there are a few attractions you don’t want to miss.

Look forward to a unique sightseeing adventure at the notable Castel Nuovo and allow yourself time to explore. Just a short distance away you'll find your next stop, Chiesa Del Gesù Nuovo, a heritage-rich church that draws visitors from far and near.

Continue your journey to Cappella Sansevero, one of the city’s most popular spots that you shouldn’t miss. Another great site to visit is the well-known Naples National Archaeological Museum.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Naples. Enjoy a relaxing evening as you savor delicious local cuisine.

Enjoy a lovely meal at Antica Pizzeria Di Matteo, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Mercure Napoli Centro Angioino is another top choice with a popular menu. You could also check for a table at La Lazzara Trattoria e Pizzeria. As an establishment that consistently gains high praises from customers, it’s an ideal choice in Naples tonight.

Keep the excitement of the evening going by visiting a bar or two. Archivio Storico - Cocktail Bar & Wonderfood is an excellent place to start. You could also check out Archeobar, offering a different kind of charm. A last recommendation for the day is Babette Pub. This bar promises an enjoyable experience with tasty drinks and a vibrant setting.

As the sun sets, rest up and recharge for the next leg of your road trip in Italy.

Your itinerary for day 9 of your road trip in Italy includes 2 stops and features some of the highlights of Naples and Caserta. At the end of the day, enjoy the comforts of a top-rated hotel in L'aquila, where you'll spend 1 night.

No visit to Naples is complete without San Carlo Theatre. This often recommended opera house is one of the top attractions in the city. Proceed to Piazza Del Plebiscito, another must-visit attraction.

As you wander through the inviting streets of Naples, soak in the lively ambiance and take the opportunity to snap some photos. Next, head to Ovo Castle. This notable castle is a traveler-favorite.

When you’re ready to jump back into the car and say goodbye to Naples, you’ll hit the road in the direction of Caserta. This drive usually takes around 44 min.

When you're ready for some sights, head to Palace Of Caserta, a popular palace in Caserta. Explore its enchanting features at your own pace before you continue your journey to your next attraction, Giardini Reali - Parco Reggia Di Caserta. This popular park is a top recommendation in the area.

At the end of the day, you will drive to L'aquila, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in L'aquila. Enjoy a relaxing evening as you savor delicious local cuisine.

Prepare for an extraordinary culinary adventure in L'aquila by booking a table at FØRMA contemporary restaurant, a Bib Gourmand restaurant that boasts an exceptional contemporary and creative menu. If you're eager to try something different, consider DECA, another top spot with a tantalizing menu.

Following your dinner, dive into the local bar culture at Art Cafè L'aquila. Enjoy this evening's relaxed ambiance with delightful drinks.

Say good night to L'aquila and look forward to another great day of your road trip in Italy!

Dive into day 10 of your remarkable road trip in Italy. Today you'll explore 2 destinations, including Santa Maria degli Angeli and Perugia. At the end of the day, you’ll unwind at one of the finest accommodations in Perugia, where you'll spend 1 night.

Fasten your seatbelt and make your way to your next stop — Santa Maria degli Angeli, home to many well-known sights in the region. Keep in mind that your travel time from L'aquila to Santa Maria degli Angeli may take around 2 hours 23 min without traffic disruptions. Upon arrival in Santa Maria degli Angeli, we highly recommend checking out some of the top attractions.

Enjoy sightseeing at your own pace and allow yourself time to explore the beautiful surroundings. Take your self-guided tour to Basilica Of San Francesco D'assisi, a notable church that everyone visiting Santa Maria degli Angeli should see.

It’s time to gear up for the next part of your road trip adventure. Under favorable conditions, your drive to Santa Maria degli Angeli may take around 9 min. Upon your arrival in Santa Maria degli Angeli, you’ll be greeted with the opportunity to do some sightseeing and exploring.

Enjoy sightseeing at your own pace and allow yourself time to explore the beautiful surroundings. Take your self-guided tour to Basilica Of Santa Maria Degli Angeli, a notable church that everyone visiting Santa Maria degli Angeli should see.

It’s time to gear up for the next part of your road trip adventure. Under favorable conditions, your drive to Perugia may take around 20 min. Upon your arrival in Perugia, you’ll be greeted with the opportunity to do some sightseeing and exploring.

For a more meaningful self-guided tour of the town's best attractions, visit Rocca Paolina, an often recommended historical landmark that is sure to impress. Take in the surroundings and enjoy the freedom of exploring at your own pace before you continue your journey. Next, head to Piazza Iv Novembre and admire its enchanting features.

When you’re done exploring for the day, you’ll drive to your hotel in Perugia. Check in and relax before you head out to tour the city.

After a day of adventure, treat yourself to an exquisite dinner at one of Perugia's best restaurants.

Dine in style at Ristorante Settimo Sigillo, a top recommendation for dinner tonight. Or, for a change of pace, Caffè Baglioni boasts a menu that's sure to impress. Also, be sure to check out Bar Pellas. Known as a local hotspot, it’s a great choice for tonight in Perugia.

Continue your lively evening at Tommi Bar, a perfect place for winding down or revving up the night, depending on which mood you’re in. Valentina is another excellent bar that offers a great selection of drinks to suit any mood. If you prefer to go somewhere else, Caffe Dal Perugino ensures a night out tailored to your taste.

Relax and look forward to more memorable moments to come!

On day 11 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, including Siena. When you’re not sightseeing, take time to relax at your chosen hotel in Florence, where you’ll be staying for 1 night.

After soaking in Perugia’s unique atmosphere, jump into the car with a full heart and drive in the direction of your next destination: Siena. Expect your car journey to take a minimum of 1 hour 23 min. When you arrive in Siena, it's time to take a break from the road.

Spend your afternoon discovering Piazza Del Campo, an astonishing public square known for its history-steeped features. Next, continue your sightseeing at Pubblico Palace, an often recommended palace.

If you're starting to feel hungry, this is a great time for a break at a nearby restaurant or cafe. When you're ready for more, stop by Siena Cathedral and uncover the details of this inviting church. Make sure to also explore Fortezza Medicea (siena), a locally appreciated monument.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Florence. Florence offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

Florence is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Florence.

Treat yourself to an extraordinary dining experience at Enoteca Pinchiorri, a 3-star Michelin restaurant offering an incredible italian contemporary menu. Alternatively, if your taste buds call for something different, Santa Elisabetta is one of the best restaurants for creative and mediterranean cuisine in Florence. This 2-star Michelin-awardee earns consistently high praises from guests. We also recommend checking out the menu at Gucci Osteria da Massimo Bottura. As a top-rated establishment with 1 Michelin star, it is an ideal choice for italian contemporary and international cuisine in the city.

After savoring a delicious meal, step into the vibrant nightlife at Manifattura, where the evening is just getting started. In the same way, Se·sto On Arno Rooftop Bar offers a unique charm perfect for experiencing the local bar scene in Florence. Il Vinile is another top-recommended bar that is sure to get you into the mood for some dancing and celebrating.

Savor another day of unforgettable experiences in Italy!

On day 12 of your road trip in Italy, your travel plans include 1 stop at the most scenic, wondrous, and interesting places in the region. Florence are on today's agenda. In the evening, you’ll end up in Pisa, where you will stay for 1 night.

Piazza Della Signoria makes a great addition to your morning plans. This widely recognized public square is an enchanting place to see in Florence. Continue your discovery at Cathedral Of Santa Maria Del Fiore, an UNESCO world heritage-listed church with stories to tell.

As you stroll around Florence, take in the distinct atmosphere and learn what makes this city so unique. Maximize your sightseeing with a visit to Ponte Vecchio. This globally renowned historical landmark offers an awe-inspiring encounter with Florence. Next, make your way to Uffizi Gallery to add another highlight to your day. After that, visit Piazzale Michelangelo, an extraordinary observation deck that’s sure to impress. Whether you decide to get entrance tickets for all attractions or you prefer admiring from a distance, amazing experiences await on this day in Florence.

At the end of the day, you will drive to Pisa, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Pisa, it's often a good idea to reserve a table in advance.

Treat yourself to a wonderful meal at Ristorante Capodimonte Pisa, a top-rated dining spot in Pisa. If you're in the mood for something new, try La Locanda Dei Pisani Doc Pisa, another premier location with a delectable menu. You might also want to book a table at Baribaldi Pisa. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Pisa.

After your meal, keep the night alive at a bar like Bar Mocambo, known for its lively atmosphere. Tree is another top recommendation that provides the perfect setting with well-crafted drinks and a welcoming ambiance. Similarly, Chupiteria offers an excellent atmosphere for those looking to amp up the evening.

Relax and recharge in preparation for another adventurous day in Italy!