13-Day Italy Self-Drive Road Trip With Itinerary from Pisa traveling south to Arezzo, Rome, Salerno, Naples, L'aquila, Perugia, and Florence

Dive into day 2 of your remarkable road trip in Italy. Today you'll explore 2 destinations, including Pisa and Tirrenia. At the end of the day, you’ll unwind at one of the finest accommodations in Arezzo, where you'll spend 1 night.

Leaning Tower Of Pisa leaves a lasting impression. This monument is one of the most globally renowned places to visit in Pisa. Next, head to Piazza Del Duomo, Pisa, a globally renowned public square, known for its picture-perfect features.

In between the sights, don’t hesitate to take small detours to explore local stores and eateries. When you’re ready to continue your adventure, head to Pisa Cathedral. This picture-perfect church is a highly recommended experience. Nearby, you'll also find Bagno Degli Americani. Visit these for an interesting touch to your journey.

When you’re done exploring for the day, you’ll drive to your hotel in Arezzo. Check in and relax before you head out to tour the city.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Arezzo. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Get ready for an unforgettable culinary journey in Arezzo by reserving a table at Octavin. Renowned as a 1-star Michelin restaurant, it offers an exceptional creative menu. If you're in the mood to try something new, consider La Clandestina, another top spot with a mouthwatering menu.

Cap off your dinner by heading to Liquid Bar, ideal for a leisurely evening with a drink in hand.

Celebrate another amazing day of your road trip adventure in Italy!

On day 3 of your road trip in Italy, your travel plans include 1 stop at the most scenic, wondrous, and interesting places in the region. Vatican City are on today's agenda. In the evening, you’ll end up in Rome, where you will stay for 3 nights.

To truly experience Arezzo, make sure to drop by Vatican Museums. This timeless art museum is a must-visit for anyone seeking a unique vacation experience. Another sight you shouldn’t miss is Sistine Chapel, one of the city’s best highlights.

Next, check out Saint Peter's Square, one of the most popular places to see in Arezzo. This square is a favorite among locals and travelers alike.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Rome. Rome offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

Rome is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Rome.

Enjoy an outstanding dining experience at La Pergola, a 3-star Michelin restaurant offering an exceptional mediterranean and contemporary menu. Alternatively, if you're in the mood for something different, consider the nearby 2-star Michelin-awardee, Il Pagliaccio, known for its delicious creative and innovative cuisine. Another highly-recommended place to eat in Rome is Enoteca La Torre, a renowned restaurant with a 2-star Guide Michelin recognition and a delicious mediterranean and creative menu.

Keep the excitement of the evening going by visiting a bar or two. La Botticella Of Poggi Giovanni is an excellent place to start. You could also check out Almalu Trastevere, offering a different kind of charm. A last recommendation for the day is Bar Viminale Di Pepi Maurilio. This bar promises an enjoyable experience with tasty drinks and a vibrant setting.

Take some time to reflect on your day and savor another beautiful night in Italy.

Day 4 of your road trip across Italy promises a magnificent time exploring what to see in Rome. You have 2 nights left in Rome. Take the opportunity to experience more of the best attractions and activities in the city.

Campo De' Fiori is perfect for a self-paced visit during the day. This standout public square is sure to impress. Next on your list is Piazza Navona, another must-visit landmark and wondrous public square renowned for its history-steeped features.

While exploring and sightseeing, take time to savor the culture of Rome by sampling some local delicacies. When you’re ready for more sightseeing, head to Pantheon. This respected monument is an essential place to visit for anyone looking for the full Rome experience. We also recommend visiting Roman Forum, a globally renowned archeological site. Nearby, you'll also find Colosseum, ready to add charm to your journey.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

After a day of adventure, treat yourself to an exquisite dinner at one of Rome's best restaurants.

Enjoy a lovely dining experience at RomAntica, a popular restaurant in Rome. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Rome at Coso Ristorante, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated DEROMA - Farine Romane. It’s yet another ideal choice to enhance your time in Rome tonight.

If you’re not ready to end the night just yet, Sant' Eustachio Caffè offers a perfect venue to relax and savor a drink. Similarly, Yellowsquare Rome is well-suited for those looking to unwind in a social setting. Caffè Portofino is another excellent spot to enjoy a nightcap after a delightful meal.

As the sun sets, rest up and recharge for the next leg of your road trip in Italy.

Day 5 offers an itinerary packed with the best things to see in Rome. You’ll stay in Rome for 1 night more, offering you enough time to explore at a relaxed pace.

Whether you decide to explore Rome on foot, use public transport, or join a guided tour, there are a few attractions you don’t want to miss.

Make time for Spanish Steps, a spectacular public square that is worthwhile a visit in the city. Nearby, you’ll find Piazza Di Spagna, enchanting visitors with its romantic appeal. Continue your exploration at Trevi Fountain. This monument is one of the city’s most wondrous spots.

Enjoy the freedom of exploring Rome at your own pace and find hidden gems along the way. If you want to see more picture-perfect spots, make sure to visit Basilica Di Santa Maria Maggiore. After exploring the church, head to the popular Circus Maximus.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Rome, it's often a good idea to reserve a table in advance.

Dine in style at Hotel de Russie, a top recommendation for dinner tonight. Or, for a change of pace, La Taverna Italiana boasts a menu that's sure to impress. Also, be sure to check out The Parrot Bar. Known as a local hotspot, it’s a great choice for tonight in Rome.

Let the evening flow smoothly from dinner to drinks at The Apartment Bar Roma, a top-rated bar in the area. For other recommendations, Hotel Hassler Roma provides a perfect setting for rounding out your night with style and great drinks.

Relax and look forward to more memorable moments to come!

On day 6 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, including Rome. When you’re not sightseeing, take time to relax at your chosen hotel in Salerno, where you’ll be staying for 1 night.

Visiting Altare Della Patria is always a good idea. This notable monument is a place that is appreciated by travelers and locals alike. Next, immerse yourself in the grand wonders of Castel Sant'angelo, a must-see castle in the city.

Consider stopping for a small bite to eat or a drink at a local eatery to keep your energy going. When you’re ready, continue your discovery with a visit to Piazza Del Popolo. This top-rated public square offers an enriching experience. For a change of pace, head to Passeggiata Del Pincio, where you can take in history-steeped features. Conclude your self-guided sightseeing tour with a visit to Villa Borghese. These sights offer a fulfilling end to a perfect day.

At the end of the day, you will drive to Salerno, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Salerno, it's often a good idea to reserve a table in advance.

Begin your culinary exploration in Salerno by securing a reservation at Re Maurì. This renowned restaurant holds 1 Michelin star and offers an exceptional menu of creative cuisine. Or, for a change of pace, L'Unico Drink & Food Salerno boasts a menu that's sure to impress.

Extend your evening after a delightful meal by visiting Hilton Bar E Gastronomia, which offers the perfect atmosphere for a night out. Moreover, The Black Monday Speakeasy Tbm is another popular option for a drink or two. Likewise, Dòmo I' Vinaino Wine Bar - Enogastronomia also provides a great ambiance for reminiscing about the day and raising a toast to your vacation.

Savor another day of unforgettable experiences in Italy!

Experience an unparalleled adventure on day 7 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 3 places, which are Amalfi, Ravello, and Pompei. At the end of the day, you will retreat to the hotel of your choice in Naples, where will spend 2 nights.

Look forward to a unique sightseeing adventure at the top-rated Amalfi Coast and allow yourself time to explore. Just a short distance away you'll find your next stop, Villa Rufolo, a visually striking historical landmark that draws visitors from far and near.

Continue your journey to Archaeological Park Of Pompeii, one of the village’s most interesting spots that you shouldn’t miss. Another great site to visit is the beloved Teatro Grande. When you're finished at the archeological site, Amphitheatre Of Pompeii awaits your visit. This archeological site is a historic highlight on today's itinerary.

When you’re done exploring for the day, you’ll drive to your hotel in Naples. Check in and relax before you head out to tour the city.

Indulge in a memorable dining experience at one of Naples's most popular restaurants, and connect with friendly locals for a true cultural experience.

Experience a harmony of flavors at Veritas in Naples by securing a reservation in advance. Known for its 1-star Michelin status, Veritas offers a delightful variety of dishes highlighting its delicious campanian and contemporary menu. If you're seeking an alternative culinary experience, be sure to explore Il Comandante, a highly recommended restaurant known for its enticing creative and mediterranean cuisine. This popular 1-star Michelin-awarded venue consistently exceeds expectations, ensuring a memorable holiday experience. Ready for another culinary adventure? Indulge your senses at ARIA, a highly acclaimed restaurant celebrated for its exceptional contemporary and modern menu.

After enjoying a fulfilling meal, continue your evening at Happening Cocktail Bar, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, Shanti Art Musik Bar offers a welcoming atmosphere for easing into the nightlife. Similarly, Gran Caffè Gambrinus provides an excellent environment for a relaxed and enjoyable evening.

Relax and look forward to more memorable moments to come!

On day 8 of your road trip, you will have an entire day to discover what to see in Naples. You’ll stay in Naples for 1 night.

Experience Castel Nuovo, a locally renowned castle in the city. Then, head to Chiesa Del Gesù Nuovo and soak in the ambiance of this photogenic church.

There are many interesting places to see in Naples, and when you are ready for more, go to Cappella Sansevero. This is one of the city’s most interesting respected spots of interest. After exploring the museum, visit the captivating Naples National Archaeological Museum.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

Naples is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Naples.

Have a fantastic dining experience at Antica Pizzeria Di Matteo, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Mercure Napoli Centro Angioino offers an enticing alternative with its varied menu. Additionally, La Lazzara Trattoria e Pizzeria is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Naples.

Cap off your dinner by heading to Archivio Storico - Cocktail Bar & Wonderfood, ideal for a leisurely evening with a drink in hand. Archeobar is another bar that offers an enjoyable setting. Similarly, Babette Pub is also a popular place to go on a night out, perfect for relaxing and socializing.

Raise your glass to another unforgettable day in Italy!

Your itinerary for day 9 of your road trip in Italy includes 2 stops and features some of the highlights of Naples and Caserta. At the end of the day, enjoy the comforts of a top-rated hotel in L'aquila, where you'll spend 1 night.

Make time for San Carlo Theatre, an underrated opera house that is worthwhile a visit in the city. Nearby, you’ll find Piazza Del Plebiscito, enchanting visitors with its history-steeped appeal. Continue your exploration at Ovo Castle. This castle is one of the city’s most locally renowned spots.

Enjoy the freedom of exploring Naples at your own pace and find hidden gems along the way. If you want to see more picture-perfect spots, make sure to visit Palace Of Caserta. After exploring the palace, head to the well-known Giardini Reali - Parco Reggia Di Caserta.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in L'aquila. L'aquila offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a day of adventure, treat yourself to an exquisite dinner at one of L'aquila's best restaurants.

Experience a symphony of flavors at FØRMA contemporary restaurant in L'aquila by securing a reservation in advance. Renowned for its Bib Gourmand distinction, FØRMA contemporary restaurant delights its guests with its exceptional variety of meals showcasing delicious contemporary and creative cuisine. Or, if you're feeling adventurous, why not try DECA? It's another excellent option with a diverse menu.

Keep the evening going at Art Cafè L'aquila, a great choice for enjoying the after-dinner hours with a drink.

Head back to your accommodation in L'aquila and get some rest to prepare for another magical day of your road trip in Italy.

Dive into day 10 of your remarkable road trip in Italy. Today you'll explore 2 destinations, including Santa Maria degli Angeli and Perugia. At the end of the day, you’ll unwind at one of the finest accommodations in Perugia, where you'll spend 1 night.

Check out the well-known church, Basilica Of San Francesco D'assisi. Afterward, continue to Basilica Of Santa Maria Degli Angeli, a church every traveler should visit. As you explore L'aquila’s charming streets, take in the lively atmosphere and get to know the character of the town.

Next, make your way to Rocca Paolina. This intriguing historical landmark is an essential stop. Following that, head to Piazza Iv Novembre, another must-visit site that will enhance your experience.

At the end of the day, you will drive to Perugia, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Perugia. Enjoy a relaxing evening as you savor delicious local cuisine.

Make sure to reserve a table at Ristorante Settimo Sigillo, an iconic dining spot in Perugia. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Caffè Baglioni, a popular restaurant in Perugia. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Bar Pellas, a hidden gem nestled in Perugia. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, Tommi Bar stands out as an excellent choice for a post-dinner cocktail. Alternatively, Valentina offers an ideal atmosphere to enjoy the pleasures of the night. Caffe Dal Perugino is also a great option that provides a perfect setting for a relaxing evening.

Relax and recharge in preparation for another adventurous day in Italy!

On day 11 of your road trip in Italy, your travel plans include 1 stop at the most scenic, wondrous, and interesting places in the region. Siena are on today's agenda. In the evening, you’ll end up in Florence, where you will stay for 1 night.

Awaiting your discovery is the widely recognized Piazza Del Campo, an enchanting public square in Perugia. Next, go to Pubblico Palace.

After visiting Piazza Del Campo and Pubblico Palace, have a stroll along Perugia's streets and take in the local charm. Continue your sightseeing by heading to Siena Cathedral. This visually striking church offers a unique experience. Fortezza Medicea (siena) is another noteworthy attraction worthwhile a visit.

When you’re done exploring for the day, you’ll drive to your hotel in Florence. Check in and relax before you head out to tour the city.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Florence. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Discover the culinary delights of Florence by securing a reservation at Enoteca Pinchiorri. Esteemed for its 3-star Guide Michelin recognition, this restaurant offers a remarkable selection of italian contemporary cuisine. For an alternative dining experience, try Santa Elisabetta, renowned for its delicious creative and mediterranean dishes. This esteemed 2-star Michelin-recipient consistently impresses guests, making it a must-visit spot during your holiday. Craving more culinary excitement? Head to Gucci Osteria da Massimo Bottura, a highly recommended local eatery celebrated for its mouthwatering italian contemporary and international menu. With its 1-star Michelin recognition, it offers an unforgettable dining adventure.

Continue your evening by exploring the vibrant nightlife scene at Manifattura, a prime destination for a thrilling night out. Also, don’t forget to check out Se·sto On Arno Rooftop Bar, a bar that offers unique local touches. Likewise, Il Vinile provides an excellent alternative for a fun evening.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in Italy.

On day 12 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, including Florence. When you’re not sightseeing, take time to relax at your chosen hotel in Pisa, where you’ll be staying for 1 night.

One of the most widely recognized attractions included on the itinerary is Piazza Della Signoria. This enchanting public square will help you start your sightseeing on top. Then, take a leisurely stroll to Cathedral Of Santa Maria Del Fiore and learn what makes this romantic church unique.

Throughout the day, make sure to take breaks to appreciate the surroundings. Next up, visit the world-famous Ponte Vecchio. After exploring the historical landmark, head to Uffizi Gallery. This famous art gallery is a highlight in Florence. As your day continues, stop by Piazzale Michelangelo, known for its history-steeped features.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Pisa. Pisa offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

Pisa is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Pisa.

Don’t miss out on dining at Ristorante Capodimonte Pisa, a top-rated dining destination in Pisa. If you're in the mood to try something new, consider La Locanda Dei Pisani Doc Pisa, another top spot with a mouthwatering menu. You might also want to secure a reservation at Baribaldi Pisa. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Pisa this evening.

If you’re not ready to end the night just yet, Bar Mocambo offers a perfect venue to relax and savor a drink. Similarly, Tree is well-suited for those looking to unwind in a social setting. Chupiteria is another excellent spot to enjoy a nightcap after a delightful meal.

Get a good night's sleep and look forward to another great day on the road in Italy!