13-Day Italy Self-Drive Road Trip With Itinerary from Rome to Florence, Siena, La Spezia, Venice, and Bologna
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Experience the freedom of the open road in Italy as you embark on an unforgettable 13-day road trip! This experience caters to every traveler, featuring destinations like Rome, Florence, Pisa, Siena, San Gimignano, Riomaggiore, La Spezia, Manarola, Venice, Bologna, and Modena.
This perfectly planned road trip itinerary in Italy takes you through some of the best places to see in the country. You will spend 4 nights in Rome, 2 nights in Florence, 1 night in Siena, 2 nights in La Spezia, 2 nights in Venice, and 1 night in Bologna. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!
With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.
Upon arriving in Rome, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.
An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Trevi Fountain and Colosseum are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Pantheon, learn more about the unique Piazza Navona, and immerse yourself in the vibrant atmosphere of Piazza San Marco.
As you hit the open road and drive through Rome, Florence, Pisa, Siena, San Gimignano, Riomaggiore, La Spezia, Manarola, Venice, Bologna, and Modena, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.
Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.
This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.
The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!
Itinerary summary
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Day 1
- Rome - Arrival day
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- Palatine Hill
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Your road trip adventure in Italy begins as soon as you reach Rome and pick up your car. You’ll stay in Rome for 3 nights and explore the best things to see and do, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.
Rome is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Palatine Hill, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.
Make your way to your chosen hotel. Check-in typically starts between 2 and 4 PM in Rome. Make yourself at home and enjoy some downtime before heading out again.
As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Rome, it's often a good idea to reserve a table in advance.
Enjoy a lovely dining experience at La Bottega Roma, a popular restaurant in Rome. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Rome at Pasta In Corso, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated Trattoria Vecchia Roma. It’s yet another ideal choice to enhance your time in Rome tonight.
Keep the evening going at La Botticella Of Poggi Giovanni, a great choice for enjoying the after-dinner hours with a drink. You could also go to Almalu Trastevere, which offers a similarly pleasant setting and great drinks. Another option is Bar Viminale Di Pepi Maurilio, which provides an inviting environment for unwinding after a busy day out.
Raise a toast to the start of your 13-day road trip in Italy!
Day 2
- Rome
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Drive 9 km, 1 hour 17 min
- Colosseum
- Roman Forum
- Trevi Fountain
- Pantheon
- Piazza Navona
- Castel Sant'Angelo
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Day 2 of your road trip across Italy promises a magnificent time exploring Rome. You have 2 nights left in Rome. Take the opportunity to experience more of the best attractions and activities in the city.
Rome is home to plenty of attractions that offer fun adventures, scenic views, and picturesque spots! Start at Colosseum, a wondrous archeological site that is worthwhile a visit in the city. Nearby, you’ll find Roman Forum, enchanting visitors with its culturally significant appeal. Continue your exploration at Trevi Fountain. This monument is one of the city’s most wondrous spots.
Enjoy the freedom of exploring Rome at your own pace and find hidden gems along the way. If you want to see more picture-perfect spots, make sure to visit Pantheon. After exploring the monument, head to the wondrous Piazza Navona. This public square will wrap up today’s self-guided sightseeing tour in the city.
Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.
As dinnertime approaches, it's time to head out for a bite to eat in Rome. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.
Enjoy a delicious meal at RomAntica, a highly-rated dining destination in Rome. If you're eager to try something different, consider Coso Ristorante, another top spot with a tantalizing menu. You might also want to secure a reservation at DEROMA - Farine Romane. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Rome this evening.
Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, Sant' Eustachio Caffè stands out as an excellent choice for a post-dinner cocktail. Alternatively, Yellowsquare Rome offers an ideal atmosphere to enjoy the pleasures of the night. Caffè Portofino is also a great option that provides a perfect setting for a relaxing evening.
Raise your glass and celebrate another amazing day of your road trip in Italy!
Day 3
- Rome
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Drive 16 km, 1 hour 4 min
- Vatican Museums
- Sistine Chapel
- St Peter's Basilica
- Piazza di Spagna
- Spanish Steps
- Trastevere
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On day 3 of your road trip, you’ll start and end your day in Rome, but spend part of the day exploring places of interest outside the immediate city. On today's itinerary, you'll find attractions in Vatican City and Rome. You still have 1 night left in Rome.
A top thing to do today is to explore Trastevere, a must-see neighborhood in Vatican City. It's the perfect starting point for touring the top attractions in the area.
Start by visiting Vatican Museums, a prime spot to begin your journey.
Piazza Di Spagna also adds charm to your journey, and Spanish Steps wraps up your day with its visually striking appeal.
When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Rome.
Indulge in a memorable dining experience at one of Rome's most popular restaurants, and connect with friendly locals for an authentic adventure.
Make sure to reserve a table at Hotel de Russie, an iconic dining spot in Rome. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of La Taverna Italiana, a popular restaurant in Rome. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of The Parrot Bar, a hidden gem nestled in Rome. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.
Cap off your dinner by heading to The Apartment Bar Roma, ideal for a leisurely evening with a drink in hand. Hotel Hassler Roma is another bar that offers an enjoyable setting.
Take some time to reflect on your day and savor another beautiful night in Italy.
Day 4
- Rome
- Florence
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Drive 281 km, 3 hours 45 min
- piazzale Michelangelo
- Basilica of Santa Croce in Florence
- Uffizi Gallery
- Ponte Vecchio
- piazza della Signoria
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Dive into day 4 of your remarkable road trip in Italy. Today you will explore Florence, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Florence. You’ll stay here for 2 nights.
Immerse yourself in Rome’s rich culture with today's sightseeing itinerary. Start your journey at Piazzale Michelangelo. This romantic observation deck is sure to ignite your curiosity. Next, dive into the culturally significant features of Basilica Of Santa Croce In Florence, a must-visit church in the city.
In between sights, stop by local stores, picturesque photo spots, and small eateries. When you’re ready for your next attraction, proceed to Uffizi Gallery, a famous art gallery. For a change of scene, check out Ponte Vecchio, known for its history-steeped features.
After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Florence. Florence offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.
As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Florence. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.
Savor the flavors at Ristorante Oliviero 1962, a top pick for dinner tonight. Alternatively, Di Poneta Novoli beckons with its unique menu offerings. Also, consider Caffe San Firenze. With its consistent customer satisfaction, it’s an excellent option for dining in Florence tonight.
Keep the evening going at Manifattura, a great choice for enjoying the after-dinner hours with a drink. You could also go to Se·sto On Arno Rooftop Bar, which offers a similarly pleasant setting and great drinks. Another option is Il Vinile, which provides an inviting environment for unwinding after a busy day out.
As the sun sets on another day of adventure, rest up and recharge for the next leg of your road trip in Italy.
Day 5
- Florence
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Drive 201 km, 3 hours 8 min
- Cathedral of Santa Maria del Fiore
- Galleria dell'Accademia
- Leaning Tower of Pisa
- Pisa Cathedral
- Piazza del Duomo, Pisa
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Greet day 5 of your road trip in Italy with a smile and start your day with a hearty breakfast. You will return to Florence for your remaining 1 night in the city later today, but first, it’s time for some exploring! On the agenda for this day, you’ll find only the best things to see and do in Florence and Pisa.
Bring your curiosity for today’s adventure around Florence. Some of the city’s most loved attractions await. Cathedral Of Santa Maria Del Fiore is the perfect place to start. This church is one of the most impressive places to visit in Florence. Next, head to Galleria Dell'accademia, a popular art gallery, known for its heritage-rich features.
In between the sights, don’t hesitate to take small detours to explore local stores and eateries. When you’re ready to continue your adventure, head to Leaning Tower Of Pisa. This breathtaking monument offers a unique experience that is highly recommended. Meanwhile, Pisa Cathedral adds its own distinct charm to your journey. Finish your day with a visit to Piazza Del Duomo, Pisa, a symbolic public square in Florence.
When you’re done exploring for the day, you’ll return to Florence and your accommodation.
As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Florence. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.
Treat yourself to a delightful dinner at Ditta Artigianale, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Trattoria Da Burde? It's another excellent option with a diverse menu. Consider reserving a table at Casa Toscana as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Florence.
Continue your lively evening at Bar 50 Rosso, a perfect place for winding down or revving up the night, depending on which mood you’re in. Bitter Bar is another excellent bar that offers a great selection of drinks to suit any mood. If you prefer to go somewhere else, Archea Brewery ensures a night out tailored to your taste.
Raise your glass and celebrate another amazing day of your road trip in Italy!
Day 6
- Florence
- Siena
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Drive 157 km, 3 hours 9 min
- Siena Cathedral
- piazza del Campo
- Porta Camollia, Siena
- Parco della Rocca
- SanGimignano1300
- Piazza del Duomo, San Gimignano
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On day 6 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Siena and San Gimignano. In the evening, you’ll end up in Siena, where you will stay for 1 night.
Whether you prefer a leisurely exploration or a more fast-paced adventure, this itinerary in Florence allows for both. Start by heading to Siena Cathedral. This well-known church provides an insightful glimpse into the city's identity. Next, discover Piazza Del Campo, a history-steeped public square, promising a delightful encounter.
Continue your sightseeing with a visit to Porta Camollia, Siena, a frequently visited monument. When you’re done, don’t forget to make a stop at the intriguing Parco Della Rocca. Round off your day at Sangimignano1300, another gem in Florence with respected features to discover.
When you’re done exploring for the day, you’ll drive to your hotel in Siena. Check in and spend some time relaxing before you head out to tour the city.
Indulge in a memorable dining experience at one of Siena's most popular restaurants, and connect with friendly locals for an authentic adventure.
Enjoy a lovely dining experience at Enoteca I Terzi, a popular restaurant in Siena. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Siena at Ristorante Tar-Tufo, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated Antica Trattoria Papei. It’s yet another ideal choice to enhance your time in Siena tonight.
To truly maximize your evening out, consider visiting Meet Life Cafè after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to Maudit Pub, another bar with an inviting ambiance. Similarly, Bar Impero Siena also offers a great atmosphere, ensuring a night filled with enjoyment and relaxation.
Head back to your accommodation in Siena and get some rest in preparation for another magical day of your road trip in Italy!
Day 7
- Siena
- La Spezia
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Drive 244 km, 3 hours 28 min
- Church of San Giovanni Battista of Riomaggiore
- Riomaggiore
- Castle of Riomaggiore
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On day 7 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, Riomaggiore. When you’re not sightseeing, take time to relax at your selected hotel in La Spezia, where you’ll be staying for 2 nights.
Start your adventure at Church Of San Giovanni Battista Of Riomaggiore. This frequently visited church is a place that is appreciated by travelers and locals alike.
Consider stopping for a small bite to eat or a drink at a local eatery to keep your energy going. When you’re ready, continue your discovery with a visit to Castle Of Riomaggiore. This increasingly popular castle offers an enriching experience.
At the end of the day, you will drive to La Spezia, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.
As you explore more of La Spezia, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.
Don’t miss out on dining at The Colombaio Park, a top-rated dining destination in La Spezia.
Relax and reminisce about your day in Italy and look forward to more memorable moments to come!
Day 8
- La Spezia
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Drive 34 km, 1 hour 12 min
- Chiesa di San Lorenzo
- Presepe di Manarola
- Manarola Overlook Viewpoint
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On day 8 of your road trip, you’ll start and end your day in La Spezia, where you'll stay for 1 night more.
A blend of family-friendly attractions, breathtaking views, and photo-friendly spots await you in La Spezia on today’s itinerary. First up is the up-and-coming church, Chiesa Di San Lorenzo. Afterward, continue to Presepe Di Manarola, an art installation every traveler should visit.
As you explore La Spezia’s charming streets, take in the lively atmosphere and get to know the character of the village. Next, make your way to Manarola Overlook Viewpoint. This often recommended observation deck is an essential stop.
When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in La Spezia.
After a day of adventure, treat yourself to an exquisite dinner at one of La Spezia's best restaurants.
Head back to your accommodation in La Spezia and get some rest in preparation for another magical day of your road trip in Italy!
Day 9
- La Spezia
- Venice
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Drive 366 km, 4 hours 33 min
- Bridge of Sighs
- Doge's Palace
- St Mark's Basilica
- St Mark's Campanile
- Piazza San Marco
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Embark on another extraordinary experience on day 9 of your road trip in Italy. Today, you will make 1 stop and experience some of the highlights of Venice. At the end of the day, you will enjoy the comforts of a top-rated hotel in Venice, which will be your home away from home for 2 nights.
A blend of family-friendly attractions, romantic experiences, and scenic views await you in La Spezia on today’s itinerary. First up is the notable monument, Bridge Of Sighs. Afterward, continue to Doge's Palace, a palace every traveler should visit.
As you explore La Spezia’s charming streets, take in the lively atmosphere and get to know the character of the city. Next, make your way to St Mark's Basilica. This captivating church is an essential stop. Following that, head to St Mark's Campanile, another must-visit site that will enhance your experience. Don’t forget to stop by Piazza San Marco, a world-famous public square in the city.
After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Venice. Venice offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.
After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Venice. Enjoy a satisfying meal that will recharge you for tonight's adventures.
Enjoy a delicious meal at Bauer Hotel, a top-rated dining destination in Venice. If you're in the mood to try something new, consider L'Osteria Le Guglie, another top spot with a mouthwatering menu. You might also want to secure a reservation at Corner Pub. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Venice this evening.
Keep the excitement of the evening going by visiting a bar or two. Al Parlamento is an excellent place to start. You could also check out The Caffe Rosso, offering a different kind of charm. A last recommendation for the day is Adagio. This bar promises an enjoyable experience with tasty drinks and a vibrant setting.
Celebrate another amazing day of your road trip adventure in Italy!
Day 10
- Venice
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Drive 1 km, 18 min
- Palazzo Contarini del Bovolo
- Rialto Bridge
- Grand Canal
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On day 10 of your road trip, you will have an entire day to explore Venice. You’ll stay in Venice for 1 night and discover all the best things to see and do in the area.
Savor the day by visiting some of the best places to see in Venice, including a palace, a historical landmark, and a street. Start your adventure at Palazzo Contarini Del Bovolo. This popular palace is a must-visit for travelers looking for a unique holiday experience. Make your way to Rialto Bridge located in Venice for an enchanting atmosphere.
Next, immerse yourself in the setting of Grand Canal. Its romantic features will captivate you.
Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.
Indulge in a memorable dining experience at one of Venice's most popular restaurants, and connect with friendly locals for an authentic adventure.
Dine in style at Generator Venice, a top recommendation for dinner tonight. Or, for a change of pace, Nevodi boasts a menu that's sure to impress. Also, be sure to check out Ristorante La Piazza. Known as a local hotspot, it’s a great choice for tonight in Venice.
After your delicious meal, get a taste of the vibrant nightlife with a visit to Il Mercante, known for its inviting atmosphere. The Irish Pub Venezia is another great option if you’re looking for a place to get the night started. Similarly, Ai Stagneri provides a great setting to enjoy the night away.
Head back to your accommodation in Venice and get some rest in preparation for another magical day of your road trip in Italy!
Day 11
- Venice
- Bologna
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Drive 155 km, 2 hours 6 min
- Piazza Santo Stefano
- Two Towers
- Palazzo Grassi, Bologna
- Fountain of Neptune, Bologna
- Piazza Maggiore
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Experience an unparalleled adventure on day 11 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 vibrant destinations - Bologna. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Bologna. You will spend 1 night here for some well-deserved relaxation.
Get ready for a day filled with fun adventures, romantic experiences, and breathtaking views in the charming city of Venice. Your adventure starts at Piazza Santo Stefano, an intriguing local hot spot. Another notable attraction to explore is Two Towers. This locally renowned monument is known for its romantic appeal.
After soaking in the highlights of these sights, take some time to wander Venice's streets and immerse yourself in the local atmosphere. When you're ready to continue your sightseeing adventure, head to Palazzo Grassi, Bologna. Fountain Of Neptune, Bologna is also worth visiting, along with Piazza Maggiore. These standout landmarks offer unique experiences that add to the day’s enjoyment.
When you’re done exploring for the day, you’ll drive to your hotel in Bologna. Check in and spend some time relaxing before you head out to tour the city.
After a day of adventure, treat yourself to an exquisite dinner at one of Bologna's best restaurants.
Have a fantastic dining experience at Ristorante Ciacco, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Ristorante Ballarini offers an enticing alternative with its varied menu. Additionally, Sfoglia Rina is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Bologna.
Continue your evening by exploring the vibrant nightlife scene at Bar Al Bricco D'oro, a prime destination for a thrilling night out. Also, don’t forget to check out Bar Freud E Squisito, a bar that offers unique local touches. Likewise, Osteria Del Sole provides an excellent alternative for a fun evening.
Say good night to Bologna and look forward to another great day of your road trip in Italy!
Day 12
- Bologna
- Rome
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Drive 462 km, 5 hours 40 min
- Enzo Ferrari Museum
- Torre Civica - Ghirlandina
- Modena Cathedral
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Dive into day 12 of your remarkable road trip in Italy. Today you will explore Modena, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Rome. You’ll stay here for 1 night.
Today, you'll explore some of the most beautiful places in Bologna, including a museum, a monument, and a church. Start your day with a visit to Enzo Ferrari Museum. This notable museum is a must-visit in the city. When you’re ready for your next discovery, continue to Torre Civica - Ghirlandina, which may be one of the most awe-inspiring places you will experience today.
One of the best things about exploring Bologna on a self-guided tour is that you set the pace. There’s plenty of time for detours and discovering hidden gems. When you’re ready for your next stop, make your way to Duomo Di Modena, a well-known church in the city.
At the end of the day, you will drive to Rome, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.
As dinnertime approaches, it's time to head out for a bite to eat in Rome. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.
Treat yourself to a wonderful meal at Sofitel Roma Villa Borghese, a top-rated dining spot in Rome. If you're in the mood for something new, try Centro, another premier location with a delectable menu. You might also want to book a table at Ristorante Tema. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Rome.
Relax and recharge in preparation for another adventurous day in Italy!
Day 13
- Rome - Departure day
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- Altare della Patria
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Day 13 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Rome before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.
If you're up for some more sightseeing, we recommend visiting Altare Della Patria, a historic monument before you head out.
As your final day in Italy unfolds, enjoy a last-minute shopping spree in Rome's best shopping area, Galleria San Pietro. Enjoy finding the perfect gift or keepsake to remind you of your wonderful trip to Italy.
Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Rome.
You’ll then say farewell to Rome. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!
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