13-Day Italy Self-Drive Road Trip With Itinerary from Rome to Florence, Siena, La Spezia, Venice, and Bologna

Day 2 of your road trip will take you to the best attractions Rome has to offer. Cherish the 2 nights you have left in the city and use the provided itinerary to discover what to see in Rome.

Rome is brimming with adventures.

Catch Colosseum before the crowds roll in. This culturally significant archeological site is sure to ignite your curiosity. Next, dive into the picture-perfect features of Roman Forum, a must-visit archeological site in the city.

In between sights, stop by local stores, picturesque photo spots, and small eateries. When you’re ready for your next attraction, proceed to Trevi Fountain, a globally renowned monument. For a change of scene, check out Pantheon, known for its instagrammable features. We also recommend visiting Piazza Navona. This public square is a must for anyone looking to experience the city to the fullest. Lastly, end your day with a visit to Castel Sant'angelo, yet another top-rated attraction in Rome.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

Rome is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Rome.

Treat yourself to a delightful dinner at RomAntica, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Coso Ristorante? It's another excellent option with a diverse menu. Consider reserving a table at DEROMA - Farine Romane as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Rome.

Continue your evening by exploring the vibrant nightlife scene at Sant' Eustachio Caffè, a prime destination for a thrilling night out. Also, don’t forget to check out Yellowsquare Rome, a bar that offers unique local touches. Likewise, Caffè Portofino provides an excellent alternative for a fun evening.

Say good night to Rome and look forward to another great day of your road trip in Italy!

On day 3 of your road trip in Italy, you’ll start and end your day in Rome, but spend the day exploring what’s beyond the city. Since you still have 1 night to spend in Rome, there’s no need to rush. Experience Vatican City and Rome to the fullest today with this curated day itinerary.

Set aside time today to explore Trastevere, a standout neighborhood that reflects the essence of the city. While you're there, you'll also be within reach of some of the city's top landmarks, making it easy to maximize your day.

Look forward to a unique sightseeing adventure at the world-famous Vatican Museums and allow yourself time to explore.

Continue your journey to St. Peter's Basilica, one of the city’s most world-famous spots that you shouldn’t miss. Another great site to visit is the world-famous Piazza Di Spagna. When you're finished at the public square, Spanish Steps awaits your visit. This public square is an enchanting highlight on today's itinerary.

When you’re done exploring for the day, you’ll return to Rome and your accommodation.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Rome, it's often a good idea to reserve a table in advance.

Enjoy a delicious meal at Hotel de Russie, a highly-rated dining destination in Rome. If you're eager to try something different, consider La Taverna Italiana, another top spot with a tantalizing menu. You might also want to secure a reservation at The Parrot Bar. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Rome this evening.

After enjoying a fulfilling meal, continue your evening at The Apartment Bar Roma, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, Hotel Hassler Roma offers a welcoming atmosphere for easing into the nightlife.

Celebrate another amazing day of your road trip adventure in Italy!

Your itinerary for day 4 of your road trip in Italy includes 1 stop and features some of the highlights of Florence. At the end of the day, enjoy the comforts of a top-rated hotel in Florence, where you'll spend 2 nights.

Start your day at Piazzale Michelangelo. This romantic observation deck is a famous place to see in Rome. Then, wander over to Basilica Of Santa Croce In Florence. If monumental sites excite you, this church will be right up your alley. Nearby, you’ll also find Uffizi Gallery. This romantic art gallery is a favorite among visitors.

Rome offers plenty to explore, ensuring every moment of your visit is filled with excitement and discovery. If you're up for more, Ponte Vecchio is a world-famous spot in the city that will captivate you with its unique charm. When you’re done at the historical landmark, don’t forget to check out the history-steeped Piazza Della Signoria. Take a moment to appreciate the fascinating details of this astonishing public square.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Florence. Florence offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Florence. Enjoy a relaxing evening as you savor delicious local cuisine.

Don’t miss out on dining at Ristorante Oliviero 1962, a top-rated dining destination in Florence. If you're in the mood to try something new, consider Di Poneta Novoli, another top spot with a mouthwatering menu. You might also want to secure a reservation at Caffe San Firenze. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Florence this evening.

Continue the enjoyment post-dinner at Manifattura, a cherished local gathering spot renowned for its welcoming atmosphere. Similarly, Se·sto On Arno Rooftop Bar offers a vibrant space for indulging in well-crafted drinks and engaging conversation. You may also want to check out Il Vinile. This bar is a favorite among both locals and visitors looking for a delightful evening out filled with laughter and fun.

Relax and recharge in preparation for another adventurous day in Italy!

Greet day 5 of your road trip in Italy with a smile and start your day with a hearty breakfast. You have 1 night to stay in Florence, so get ready to make the most of your time in the region. On the agenda for this day, you’ll find only the best things to see and do in Florence and Pisa.

Whether you decide to explore Florence on foot, use public transport, or join a guided tour, there are a few attractions you don’t want to miss.

One of the most top-rated attractions included on the itinerary is Cathedral Of Santa Maria Del Fiore. This UNESCO world heritage-designated church will help you start your sightseeing on top. Then, take a leisurely stroll to Galleria Dell'accademia and learn what makes this noteworthy art gallery unique.

Throughout the day, make sure to take breaks to appreciate the surroundings. Next up, visit the world-famous Leaning Tower Of Pisa. After exploring the monument, head to Pisa Cathedral. This locally appreciated church is a highlight in Florence. As your day continues, stop by Piazza Del Duomo, Pisa, known for its stunning features.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Florence.

Indulge in a memorable dining experience at one of Florence's most popular restaurants, and connect with friendly locals for a true cultural experience.

Treat yourself to a delicious dinner at Ditta Artigianale, an excellent option for tonight's dining. Looking for something different? Trattoria Da Burde offers a tantalizing alternative with its diverse menu. And don’t miss Casa Toscana. Known for great service, it’s a fantastic choice for tonight in Florence.

After your meal, keep the night alive at a bar like Bar 50 Rosso, known for its lively atmosphere. Bitter Bar is another top recommendation that provides the perfect setting with well-crafted drinks and a welcoming ambiance. Similarly, Archea Brewery offers an excellent atmosphere for those looking to amp up the evening.

Take some time to reflect on your day and savor another beautiful night in Italy.

Experience an unparalleled adventure on day 6 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 2 places, which are Siena and San Gimignano. At the end of the day, you will retreat to the hotel of your choice in Siena, where will spend 1 night.

No visit to Florence is complete without Siena Cathedral. This popular church is one of the top attractions in the city. Proceed to Piazza Del Campo, another must-visit attraction.

As you wander through the inviting streets of Florence, soak in the lively ambiance and take the opportunity to snap some photos. Next, head to Porta Camollia, Siena. This increasingly popular monument is a traveler-favorite. Not far away, you’ll find Parco Della Rocca, another key site on your sightseeing itinerary. Sangimignano1300 is yet another highly recommended place to visit nearby, offering plenty to discover for curious travelers. Conclude your day at Piazza Del Duomo and uncover why it's recognized as one of the city's most frequently visited attractions.

When you’re done exploring for the day, you’ll drive to your hotel in Siena. Check in and relax before you head out to tour the city.

After a day of adventure, treat yourself to an exquisite dinner at one of Siena's best restaurants.

Dine in style at Enoteca I Terzi, a top recommendation for dinner tonight. Or, for a change of pace, Ristorante Tar-Tufo boasts a menu that's sure to impress. Also, be sure to check out Antica Trattoria Papei. Known as a local hotspot, it’s a great choice for tonight in Siena.

After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at Meet Life Cafè, a well-loved spot among locals and tourists. Or, head to Maudit Pub. This bar boasts a welcoming environment that is perfect for winding down. You could also continue your night at Bar Impero Siena, another top-rated place in the area.

Take some time to reflect on your day and savor another beautiful night in Italy.

Dive into day 7 of your remarkable road trip in Italy. Today you'll explore 1 destination, including Riomaggiore. At the end of the day, you’ll unwind at one of the finest accommodations in La Spezia, where you'll spend 2 nights.

To truly experience Siena, make sure to drop by Church Of San Giovanni Battista Of Riomaggiore. This often recommended church is a must-visit for anyone seeking a unique vacation experience. Another sight you shouldn’t miss is Riomaggiore, one of the village’s best highlights.

Next, check out Castle Of Riomaggiore, one of the most worthwhile places to see in Siena. This castle is a favorite among locals and travelers alike.

At the end of the day, you will drive to La Spezia, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

La Spezia is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in La Spezia.

Enjoy a lovely meal at The Colombaio Park, a top-rated place to have dinner tonight.

Raise your glass to another unforgettable day in Italy!

On day 8 of your road trip, you’ll start and end your day in La Spezia, where you still have 1 night left. You'll spend part of the day exploring places of interest outside the immediate city, including Manarola.

No visit to La Spezia is complete without Chiesa Di San Lorenzo. This frequently visited church is one of the top attractions in the village. Proceed to Presepe Di Manarola, another must-visit attraction.

As you wander through the inviting streets of La Spezia, soak in the lively ambiance and take the opportunity to snap some photos. Next, head to Manarola Overlook Viewpoint. This increasingly popular observation deck is a traveler-favorite.

When you’re done exploring for the day, you’ll return to La Spezia and your accommodation.

La Spezia is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in La Spezia.

Relax and recharge in preparation for another adventurous day in Italy!

On day 9 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, including Venice. When you’re not sightseeing, take time to relax at your chosen hotel in Venice, where you’ll be staying for 2 nights.

Make a stop at Bridge Of Sighs. This notable monument is a must-visit for travelers looking for a unique holiday experience. Make your way to Doge's Palace located in La Spezia for another exciting encounter.

Next, immerse yourself in the setting of St Mark's Basilica. Its history-steeped features will captivate you. After the church, continue your tour of the city with a visit to St Mark's Campanile. Visitors usually appreciate the visually striking features of this monument. Next up is Piazza San Marco, a highly recommended public square.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Venice. Venice offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

Indulge in a memorable dining experience at one of Venice's most popular restaurants, and connect with friendly locals for a true cultural experience.

Treat yourself to a wonderful meal at Bauer Hotel, a top-rated dining spot in Venice. If you're in the mood for something new, try L'Osteria Le Guglie, another premier location with a delectable menu. You might also want to book a table at Corner Pub. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Venice.

Continue your evening by exploring the vibrant nightlife scene at Al Parlamento, a prime destination for a thrilling night out. Also, don’t forget to check out The Caffe Rosso, a bar that offers unique local touches. Likewise, Adagio provides an excellent alternative for a fun evening.

Savor another day of unforgettable experiences in Italy!

Day 10 offers an itinerary packed with the best things to see in Rome. You’ll stay in Venice for 1 night more, offering you enough time to explore at a relaxed pace.

Whether you decide to explore Venice on foot, use public transport, or join a guided tour, there are a few attractions you don’t want to miss.

No visit to Venice is complete without Palazzo Contarini Del Bovolo. This well-known palace is one of the top attractions in the city. Proceed to Rialto Bridge, another must-visit attraction.

As you wander through the inviting streets of Venice, soak in the lively ambiance and take the opportunity to snap some photos. Next, head to Grand Canal. This beloved street is a traveler-favorite.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Venice. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Enjoy a lovely meal at Generator Venice, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Nevodi is another top choice with a popular menu. You could also check for a table at Ristorante La Piazza. As an establishment that consistently gains high praises from customers, it’s an ideal choice in Venice tonight.

After enjoying a fulfilling meal, continue your evening at Il Mercante, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, The Irish Pub Venezia offers a welcoming atmosphere for easing into the nightlife. Similarly, Ai Stagneri provides an excellent environment for a relaxed and enjoyable evening.

Savor another day of unforgettable experiences in Italy!

On day 11 of your road trip in Italy, your travel plans include 1 stop at the most scenic, wondrous, and interesting places in the region. Bologna are on today's agenda. In the evening, you’ll end up in Bologna, where you will stay for 1 night.

Your adventure in Venice is only getting started when you visit Piazza Santo Stefano, a curiosity-inducing local hot spot. Another notable attraction to explore is Two Towers. This notable monument is known for its visually striking appeal.

After soaking in the highlights of these sights, take some time to wander Venice's streets and immerse yourself in the local atmosphere. When you're ready to continue your sightseeing adventure, head to Palazzo Grassi, Bologna. Fountain Of Neptune, Bologna is also worth visiting, along with Piazza Maggiore. These standout landmarks offer unique experiences that add to the day’s enjoyment.

When you’re done exploring for the day, you’ll drive to your hotel in Bologna. Check in and relax before you head out to tour the city.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Bologna. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Have a fantastic dining experience at Ristorante Ciacco, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Ristorante Ballarini offers an enticing alternative with its varied menu. Additionally, Sfoglia Rina is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Bologna.

Unwind after your meal by stepping into Bar Al Bricco D'oro. This venue is celebrated for its extensive drink selections and cozy vibes. Alternatively, Bar Freud E Squisito offers a dynamic and energetic atmosphere for a glass or two. Don’t overlook Osteria Del Sole, another top-rated bar in the area.

Relax and look forward to more memorable moments to come!

Your itinerary for day 12 of your road trip in Italy includes 1 stop and features some of the highlights of Modena. At the end of the day, enjoy the comforts of a top-rated hotel in Rome, where you'll spend 1 night.

Look forward to a unique sightseeing adventure at the popular Enzo Ferrari Museum and allow yourself time to explore. Just a short distance away you'll find your next stop, Torre Civica - Ghirlandina, a breathtaking monument that draws visitors from far and near.

Continue your journey to Duomo Di Modena, one of the city’s most notable spots that you shouldn’t miss.

At the end of the day, you will drive to Rome, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Rome, it's often a good idea to reserve a table in advance.

Enjoy a delicious meal at Sofitel Roma Villa Borghese, a highly-rated dining destination in Rome. If you're eager to try something different, consider Centro, another top spot with a tantalizing menu. You might also want to secure a reservation at Ristorante Tema. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Rome this evening.

Celebrate another amazing day of your road trip adventure in Italy!