Travel packages in Italy

Road trips in Italy

13-Day Italy Self-Drive Road Trip With Itinerary from Rome to Florence, Pisa, Arezzo, Naples, and Salerno and surrounding area

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Photo of piazza de spagna in Rome, Italy.

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Explore the best of Italy on a remarkable 13-day road trip! Combine exploration with relaxation on a self-drive tour featuring Rome, Florence, Pisa, Siena, Arezzo, Caserta, Cardito, Naples, Pompei, Salerno, Ravello, and Amalfi.

This perfectly planned road trip itinerary takes you through some of the best places to see in Italy. You will spend 5 nights in Rome, 2 nights in Florence, 1 night in Pisa, 1 night in Arezzo, 2 nights in Naples, and 1 night in Salerno. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Rome, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Trevi Fountain and Colosseum are just a couple of the bucket-list attractions that await your discovery.

As you hit the open road and drive through Rome, Florence, Pisa, Siena, Arezzo, Caserta, Cardito, Naples, Pompei, Salerno, Ravello, and Amalfi, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.

Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!

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Driver’s age is 30 - 65

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Day 1

Rome - Arrival day
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Altare della Patria
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Welcome to Rome, the perfect starting point for your road trip in Italy! Pick up your rental car and let the adventure begin. You will spend 4 nights discovering what to see in Rome before embarking on the next leg of your journey.

Rome is a beautiful city with plenty to discover. Taking a stroll in the city center is a great alternative. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Find your way to your hotel in Rome. We recommend choosing a hotel in a central location for easy exploring. Check-in typically starts between 2 and 4 PM at hotels in Italy. Settle in and make plans for the evening.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Rome, it's often a good idea to reserve a table in advance.

Raise a toast to the start of your 13-day road trip in Italy!

Day 2

Rome
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Drive 10 km, 41 min

Colosseum
Circus Maximus
Roman Forum
Campo de' Fiori
Pantheon
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You have 3 nights left in Rome. Take the opportunity to experience more of the best attractions and activities in the city.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

Rome is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Rome.

Raise your glass to another unforgettable day in Italy!

Day 3

Rome
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Drive 27 km, 1 hour 22 min

Foro Italico
Castel Sant'Angelo
Piazza Navona
Trevi Fountain
piazza del Popolo
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You’ll stay in Rome for 2 nights.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Rome. Enjoy a relaxing evening as you savor delicious local cuisine.

Raise your glass and celebrate another amazing day of your road trip in Italy!

Day 4

Rome
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Drive 15 km, 54 min

Villa Borghese
Spanish Steps
Piazza di Spagna
Basilica di Santa Maria Maggiore
Archbasilica of St. John Lateran
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Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

After a day of adventure, treat yourself to an exquisite dinner at one of Rome's best restaurants.

As the sun sets, rest up and recharge for the next leg of your road trip in Italy.

Day 5

Rome
Florence
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Drive 281 km, 3 hours 25 min

Saint Peter's Square
St Peter's Basilica
Sistine Chapel
Vatican Museums
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Your itinerary for day 5 of your road trip in Italy includes 1 stop and features some of the highlights of Vatican City. At the end of the day, enjoy the comforts of a top-rated hotel in Florence, where you'll spend 2 nights.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Florence. Florence offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Florence, it's often a good idea to reserve a table in advance.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in Italy.

Day 6

Florence
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Drive 15 km, 1 hour 2 min

Central Market
Basilica of Santa Maria Novella
Galleria dell'Accademia
Cathedral of Santa Maria del Fiore
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Day 6 offers an itinerary packed with the best things to see in Rome. You’ll stay in Florence for 1 night more, offering you enough time to explore at a relaxed pace.

Whether you decide to get entrance tickets for all attractions or you prefer admiring from a distance, amazing experiences await on this day in Florence.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

Indulge in a memorable dining experience at one of Florence's most popular restaurants, and connect with friendly locals for a true cultural experience.

Celebrate another amazing day of your road trip adventure in Italy!

Day 7

Florence
Pisa
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Drive 95 km, 1 hour 50 min

piazza della Signoria
Basilica of Santa Croce in Florence
Uffizi Gallery
piazzale Michelangelo
The Boboli Gardens
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Experience an unparalleled adventure on day 7 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 place, which are Florence. At the end of the day, you will retreat to the hotel of your choice in Pisa, where will spend 1 night.

At the end of the day, you will drive to Pisa, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Pisa. Enjoy a relaxing evening as you savor delicious local cuisine.

Relax and recharge in preparation for another adventurous day in Italy!

Day 8

Pisa
Arezzo
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Drive 218 km, 3 hours 44 min

Piazza del Duomo, Pisa
Leaning Tower of Pisa
Knights' Square
piazza del Campo
Siena Cathedral
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On day 8 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 2 destinations, including Pisa and Siena. When you’re not sightseeing, take time to relax at your chosen hotel in Arezzo, where you’ll be staying for 1 night.

When you’re done exploring for the day, you’ll drive to your hotel in Arezzo. Check in and relax before you head out to tour the city.

After a day of adventure, treat yourself to an exquisite dinner at one of Arezzo's best restaurants.

Say good night to Arezzo and look forward to another great day of your road trip in Italy!

Day 9

Arezzo
Naples
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Drive 434 km, 4 hours 51 min

Giardini Reali - Parco Reggia di Caserta
Palace of Caserta
Villa Comunale di Cardito "Parco Taglia"
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Dive into day 9 of your remarkable road trip in Italy. Today you'll explore 2 destinations, including Caserta and Cardito. At the end of the day, you’ll unwind at one of the finest accommodations in Naples, where you'll spend 2 nights.

Whether you decide to get entrance tickets for all attractions or you prefer admiring from a distance, amazing experiences await on this day in Arezzo.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Naples. Naples offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Naples. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Head back to your accommodation in Naples and get some rest to prepare for another magical day of your road trip in Italy.

Day 10

Naples
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Drive 15 km, 57 min

Cappella Sansevero
Napoli Sotterranea Percorso Ufficiale
Naples National Archaeological Museum
Castel Sant'Elmo
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You have 1 night left in Naples. Take the opportunity to experience more of the best attractions and activities in the city.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Naples. Enjoy a satisfying meal that will recharge you for tonight's adventures.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in Italy.

Day 11

Naples
Salerno
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Drive 64 km, 1 hour 25 min

piazza del Plebiscito
Castel Nuovo
Ovo Castle
Archaeological Park of Pompeii
Amphitheatre of Pompeii
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On day 11 of your road trip in Italy, your travel plans include 2 stops at the most scenic, wondrous, and interesting places in the region. Naples and Pompei are on today's agenda. In the evening, you’ll end up in Salerno, where you will stay for 1 night.

At the end of the day, you will drive to Salerno, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

Salerno is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Salerno.

Savor another day of unforgettable experiences in Italy!

Day 12

Salerno
Rome
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Drive 315 km, 5 hours 7 min

Cattedrale di Santa Maria degli Angeli, San Matteo e San Gregorio VII
Villa Rufolo
Villa Cimbrone Gardens
Amalfi Coast
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Your itinerary for day 12 of your road trip in Italy includes 4 stops and features some of the highlights of Salerno, Ravello, Castiglione, and Amalfi. At the end of the day, enjoy the comforts of a top-rated hotel in Rome, where you'll spend 1 night.

When you’re done exploring for the day, you’ll drive to your hotel in Rome. Check in and relax before you head out to tour the city.

Indulge in a memorable dining experience at one of Rome's most popular restaurants, and connect with friendly locals for a true cultural experience.

Raise your glass to another unforgettable day in Italy!

Day 13

Rome - Departure day
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largo di Torre Argentina
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Day 13 of your road trip in Italy is your departure day. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!

How it works

Book your journey with Europe’s biggest travel platform—expert itineraries, instant confirmation, and full flexibility with 24/7 support.

Secure your spot

Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.

Get instant confirmation

Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.

Personalize your itinerary

Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.

Easily make changes

Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.

Enjoy seamless planning

With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.

Explore with confidence

From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

Secure your spot

Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.

Get instant confirmation

Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.

Personalize your itinerary

Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.

Easily make changes

Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.

Enjoy seamless planning

With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.

Explore with confidence

From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

We guarantee

Your trip is protected, personalized, and priced right. No surprises, no stress.

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