14-Day Self-Drive Road Trip in Italy, France, and Switzerland With Itinerary from Rome to Siena, Milan, Basel, Mulhouse, Lugano, and Florence

Wake up and see what day 2 of your great European road trip in Italy, France, and Switzerland has in store for you! You will be staying in Rome for 1 night before continuing your journey to the next destination.

Colosseum is a travelers’ favorite in Rome, and today you’ll have the opportunity to discover it too! This one-of-a-kind attraction is rated an average of 4.7 out of 5 stars from 328,821 visitors. More than 7,400,000 people visit this extraordinary archeological site and local gem every year to experience its uniqueness.

In Rome, don’t miss Roman Forum, a great archeological site and place to see in the city. This outstanding attraction has an average rating of 4.7 out of 5 stars from 114,450 reviews.

Check other top attractions in Rome off your list when you visit the wonderful Pantheon. This popular sight is an outstanding monument, rated an average of 4.8 out of 5 stars by 189,682 travelers. Approximately 30,000,000 people visit this attraction each year.

Beyond the above-mentioned top sights, take the opportunity to visit the outstanding Piazza Navona. This public square and place of interest has a rating of 4.7 out of 5 stars from 158,771 reviews.

If you’re keen to explore even more, the fantastic Castel Sant'angelo awaits. This castle is a tourist hot spot, garnering an average rating of 4.7 out of 5 stars from 72,431 visitors. The fantastic Castel Sant'angelo gets around 918,591 yearly visitors.

Experience shopping bliss at Rome as you explore Via del Corso. Take a leisurely stroll through unique and shops, where local treasures are waiting to be found. Beyond shopping, Via del Corso offers more options, including unique attractions, key services, and vibrant events.

As the day slows down and turns into evening, we encourage you to indulge your taste buds at one of the top-rated restaurants in Rome. After a delicious dinner, experience the local nightlife or unwind at one of the city’s most popular bars.

Begin your culinary exploration in Rome by securing a reservation at La Pergola. This renowned restaurant holds 3 Michelin star and offers an exceptional menu of mediterranean and contemporary cuisine. For another dining delight, visit Il Pagliaccio, celebrated for its delectable creative and innovative menu. This acclaimed 2-star Michelin-recipient consistently leaves guests satisfied, making it a must-visit during your holiday. Looking for a different experience? Discover Enoteca La Torre, a top local spot known for its tantalizing mediterranean and creative menu. With a 2-star Michelin recognition, it guarantees an exceptional dining adventure.

Explore the vibrant nightlife at Sant' Eustachio Caffè after your meal, a hub for lively evenings and memorable moments. Or, head to Yellowsquare Rome for a great selection of flavorful drinks and a charming setting. Furthermore, Caffè Portofino is perfect for those looking to extend their night with a touch of local flavor.

Take in the ambiance of Rome as this vacation day slowly comes to an end. Whether you’re going bar hopping or you decide on a quiet night at your hotel, you have another exciting day of your road trip to look forward to!

Dive into day 3 of your remarkable multi-country road trip across Italy, France, and Switzerland. Today's main destinations are Rome in Italy, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Siena. You’ll stay here for 1 night.

One place travelers keep coming back to in Rome is the magnificent Trevi Fountain. Around 343,494 visitors have rated this excellent monument and travel destination an average of 4.8 out of 5 stars.

We also recommend you explore the amazing Piazza Di Spagna on this leg of your adventure in Italy. This attraction is a well-known public square that has an average rating of 4.7 out of 5 stars from around 113,658 travelers.

The remarkable Spanish Steps is known to be one of the best places to visit in Rome, and its average rating of 4.5 out of 5 stars from 57,211 traveler reviews is proof.

Dive deeper into Rome by exploring the captivating Piazza Del Popolo. With a stellar average rating of 4.6 out of 5 stars from 89,807 travelers, make sure this wonderful site is on your Rome exploration list!

After a long day of driving and exploring, you’ll check in at a top-recommended hotel in Siena of your choice.

As the sun sets on day 3 of your multi-country road trip in Europe, prepare for a culinary journey. Navigate through Siena's top restaurants and eateries, each offering a local taste of Italy to remember your trip by. After a fulfilling dinner, dive into the city’s local nightlife. Whether you prefer the bustling energy of popular pubs or want to take in the ambiance of a quiet bar, Siena has them.

Savor the flavors at Enoteca I Terzi, a top pick for dinner tonight. Alternatively, Ristorante Tar-Tufo beckons with its unique menu offerings. Also, consider Antica Trattoria Papei. With its consistent customer satisfaction, it’s an excellent option for dining in Siena tonight.

Cap off your dinner by heading to Meet Life Cafè, ideal for a leisurely evening with a drink in hand. Maudit Pub is another bar that offers an enjoyable setting. Similarly, Bar Impero Siena is also a popular place to go on a night out, perfect for relaxing and socializing.

Relax, recharge, and look forward to what tomorrow holds. The opportunities are endless with a European self-drive tour!

Day 5 of your multi-country road trip promises a full day of discoveries in beautiful Milan. Enjoy time off the road as you’ll be staying in the city for 1 night more before hitting the road again.

In Milan, the extraordinary Piazza Gae Aulenti awaits. This attraction is a valued public square that boasts an average rating of 4.6 out of 5 stars from 30,398 travelers' reviews.

Another of the best travel destinations in Milan, which gets around 417 annual visits, is the spectacular Pinacoteca Di Brera. This attraction is an art gallery that is rated an average of 4.7 out of 5 stars by 26,077 visitors, making it a captivating highlight for all travelers.

You could then travel to the amazing La Scala. This local opera house and wonder has an overall review score of 4.7 out of 5 stars from 26,219 visitors, proving its popularity among travelers.

Galleria Vittorio Emanuele Ii is another attraction you might want to add to your Milan exploration itinerary. This shopping mall is a popular stop among travelers in the area, as seen in its average rating of 4.7 out of 5 stars in 91,394 reviews.

If you’re interested in seeing something outstanding today, consider dropping by a well-loved spot among locals — Duomo Di Milano Museum. More than a popular church and attraction, Duomo Di Milano Museum offers visitors an immersive journey of the rich cultural tapestry of Milan. Captivating approximately 341,609 people each year, Duomo Di Milano Museum boasts an average rating of 4.8 out of 5 stars from 138,554 traveler reviews.

After a day of exploration and awe-inspiring sights, it’s time to replenish your strength. Make the most of this stop on your multi-country road trip across Italy, France, and Switzerland by rewarding yourself with a taste of Milan’s local cuisine. After dinner, head out to a bar to relax or mingle with the locals and raise a toast to your exciting road trip adventure.

Treat yourself to a delightful dinner at Dessert Bar Milano, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Radisson Blu Hotel Milan? It's another excellent option with a diverse menu. Consider reserving a table at Ristorante Qui Si Mangia as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Milan.

After enjoying a fulfilling meal, continue your evening at Kilburn Cocktail Bar Milano, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, Bar Frida offers a welcoming atmosphere for easing into the nightlife. Similarly, The Friends Pub Milano provides an excellent environment for a relaxed and enjoyable evening.

Relax, recharge, and look forward to what tomorrow holds. The opportunities are endless with a European self-drive tour!

Embark on another extraordinary experience on day 6 of your multi-country road trip in Europe, where you’ll be making 2 stops. The highlights of today include the wonderful destinations of Milan in Italy and Lucerne in Switzerland. At the end of the day, you will enjoy the comforts of a top-rated hotel in Basel, your home for 1 night.

Explore multiple popular travel destinations in Milan today. Begin your sightseeing with a visit to the outstanding Sforzesco Castle Art Library. This attraction boasts an average rating of 4.6 out of 5 stars from 68,714 visitors.

Next, discover the charms of the popular Parco Sempione. This incredible attraction and park holds an average rating of 4.6 out of 5 stars, thanks to 72,914 visitors.

According to travelers in Milan, the extraordinary Arch Of Peace is a must-see attraction. This crowd-favorite destination and monument is rated an average of 4.6 out of 5 stars by 27,502 visitors.

As you’ve unraveled the marvels of Milan, it’s time to gear up for the next part of your road trip adventure. Set course for Switzerland! Under favorable conditions, your drive to Lucerne may take around 2 hours 58 min. Upon your arrival in Lucerne, you’ll be greeted with the opportunity to do some sightseeing and exploring.

You'll enjoy easy access to the most remarkable sights in Lucerne, including the outstanding Chapel Bridge. Having an average rating of 4.7 out of 5 stars in 30,595 reviews, this fascinating historical landmark and attraction is one of the top travel destinations in the city.

After a long day of discovery, it's time to settle in at a top-rated hotel in Basel. Indulge in well-deserved rest and rejuvenation, preparing for the continued adventure that lies ahead.

As the day unfolds, you’ll be delighted to find that the city of Basel boasts an array of restaurants and bars catering to every budget. Take this opportunity to sample the distinctive flavors of Switzerland.

Experience a taste of local culinary excellence while in Basel by securing a table at Cheval Blanc by Peter Knogl. An esteemed 3-star Michelin restaurant, it features an exceptional classic french menu. For an alternative taste experience, visit roots, famous for its scrumptious modern and seasonal dishes. This 2-star Michelin venue consistently impresses guests, making it a standout addition to your holiday plans. Looking for another choice? Discover Stucki - Tanja Grandits, a local favorite celebrated for its exquisite creative and modern cuisine in Basel. Located in the heart of the city, this 2-star Michelin restaurant is an ideal pick for creative and modern cuisine lovers seeking top-notch culinary experiences.

Keep the excitement of the evening going by visiting a bar or two. Schall Und Rauch Bar is an excellent place to start. You could also check out Grenzwert Bar, offering a different kind of charm. A last recommendation for the day is 8 Bar. This bar promises an enjoyable experience with tasty drinks and a vibrant setting.

Celebrate day 6 of your multi-country road trip in Europe with a toast, and look forward to more memorable moments to come!

Experience an unparalleled adventure on day 7 of your multi-country journey across Italy, France, and Switzerland. This exciting part of your road trip invites you to discover the renowned landmarks in 1 vibrant destinations - Basel in Switzerland. After a day filled with exploration and new experiences, you will retreat to Mulhouse where you'll spend 2 nights of well-deserved relaxation.

You'll enjoy easy access to the most remarkable sights in Basel, including the outstanding Middle Bridge. Having an average rating of 4.6 out of 5 stars in 6,094 reviews, this fascinating historical landmark and attraction is one of the top travel destinations in the city.

Basel is also home to the captivating Basel Minster, a local church considered one of the highlights of the city. About 7,564 visitors have rated this incredible site with 4.6 out of 5 stars, proving its popularity.

The extraordinary Tinguely Fountain is another unforgettable place you can visit on this leg of your journey in Basel. This extraordinary art installation and tourist hot spot boasts a rating of 4.6 out of 5 stars from 4,202 travelers.

A trip to the wonderful Basel Zoo will inspire you as it does to more than 2,012,511 travelers every year. Visitors have rated their experience at this amazing zoo and attraction an average of 4.5 out of 5 stars in 15,396 reviews.

Once you're ready to continue your road trip, it's time to buckle up and drive towards France, eagerly anticipating your arrival in Mulhouse. This drive usually takes around 38 min, without any stops or traffic disruptions.

This outstanding travel destination inspires so many travelers each year.

Take some time off from the road, it’s time to check in at a top-rated stay in Mulhouse. Choose a hotel where you can gently let go of the day’s excitement and enjoy some peace and relaxation.

After a day of exploration and awe-inspiring sights, it’s time to replenish your strength. Make the most of this stop on your multi-country road trip across Italy, France, and Switzerland by rewarding yourself with a taste of Mulhouse’s local cuisine. After dinner, head out to a bar to relax or mingle with the locals and raise a toast to your exciting road trip adventure.

Enjoy a lovely meal at Volfoni Mulhouse, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Winstub Factory is another top choice with a popular menu. You could also check for a table at Restaurant Aux Halles du Marché. As an establishment that gains consistently high praises from customers, it’s an ideal choice in Mulhouse tonight.

If you’re not ready to end the night just yet, Shamrock offers a perfect venue to relax and savor a drink. Similarly, Pub Murphy's is well-suited for those looking to unwind in a social setting. La Quille is another excellent spot to enjoy a nightcap after a delightful meal.

Savor the moment and raise a toast to yet another amazing day of your vacation in Italy, France, and Switzerland! Enjoy your evening in Mulhouse to the fullest by mingling with the locals at a bar, taking a stroll around the city center, or simply relaxing.

On day 8 of your European tour in Italy, France, and Switzerland, you’ll start and end your day in Colmar, but spend the day exploring what’s beyond the town. Since you will return to Mulhouse for 1 night more, there’s no need to rush. Experience Colmar in France to the fullest today with this curated day itinerary!

Continue your road trip and head to your next destination, Colmar. This car ride takes around 42 min.

In Colmar, the extraordinary Musée Bartholdi awaits. This attraction is a valued museum that boasts an average rating of 4.3 out of 5 stars from 690 travelers' reviews. Hosting around 16,029 visitors every year, the amazing Musée Bartholdi is undoubtedly one of the top sights of the area.

Another of the best travel destinations in Colmar is the spectacular St Martin's Church. This attraction is a church that is rated an average of 4.4 out of 5 stars by 1,904 visitors, making it a captivating highlight for all travelers.

You could then travel to the amazing Petite Venise In Colmar. This local street and wonder has an overall review score of 4.6 out of 5 stars from 39,311 visitors, proving its popularity among travelers.

Petit Train Touristique De Colmar (vert) - Train's is another attraction you might want to add to your Colmar exploration itinerary. This tramway is a popular stop among travelers in the area, as seen in its average rating of 4.2 out of 5 stars in 3,314 reviews.

Fasten your seatbelt and make your way to your next stop. Munster, home to many well-known sights in the region, is a lovely destination on today’s itinerary. Keep in mind that your travel time from Colmar to Munster may take around 24 min without traffic disruptions. Upon arrival in Munster, we highly recommend checking out some of the top attractions.

Complement your beautiful day with a visit to a top-rated nature reserve and attraction in Munster — Parc Naturel Régional Des Ballons Des Vosges. About 22,175 visitors have rated this attraction an average of 4.5 out of 5 stars.

After a day of exploration and awe-inspiring sights, it’s time to replenish your strength. Make the most of this stop on your multi-country road trip across Italy, France, and Switzerland by rewarding yourself with a taste of Mulhouse’s local cuisine. After dinner, head out to a bar to relax or mingle with the locals and raise a toast to your exciting road trip adventure.

Have a fantastic dining experience at Au Bureau Mulhouse, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Les Saveurs Du Liban offers an enticing alternative with its varied menu. Additionally, L'Entrecôte de Mulhouse is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Mulhouse.

After your meal, keep the night alive at a bar like Les 3 Singes - Mulhouse, known for its lively atmosphere. Le Pub Fiction is another top recommendation that provides the perfect setting with well-crafted drinks and a welcoming ambiance. Similarly, The Tavern Of The Teutonic Knights offers an excellent atmosphere for those looking to amp up the evening.

Relax, recharge, and look forward to what tomorrow holds. The opportunities are endless with a European self-drive tour!

On day 9 of your exciting European self-drive vacation in Italy, France, and Switzerland, you’ll soak in the magnificence of 1 destination, Colmar in France. When you’re not exploring the town and its surrounding areas, take time to relax at your selected hotel in Lugano, where you’ll be staying for 1 night.

Colmar’s wonders await as you prepare for another journey on the road, leaving the breathtaking surroundings of Mulhouse behind. This drive usually takes around 38 min. Colmar welcomes you with a multitude of unique vacation experiences.

One place travelers keep coming back to in Colmar is the magnificent Statue De La Liberté. Around 1,939 visitors have rated this excellent monument and travel destination an average of 4.3 out of 5 stars.

We also recommend you explore the amazing Parc Du Champ De Mars on this leg of your adventure in France. This attraction is a well-known park that has an average rating of 4.5 out of 5 stars from around 4,547 travelers.

The remarkable Fontaine Dédiée À L'amiral Bruat is known to be one of the best places to visit in Colmar, and its average rating of 4.4 out of 5 stars from 1,111 traveler reviews is proof.

Dive deeper into Colmar by exploring the captivating Jardin Méquillet. With a stellar average rating of 4.2 out of 5 stars from 315 travelers, make sure this wonderful site is on your Colmar exploration list!

When you’ve had your share of Colmar, prepare for your next destination. Admire the views and listen to some good music as you drive in the direction of Lugano, Switzerland. Your travel time is around 3 hours 41 min.

This outstanding travel destination inspires so many travelers each year.

An exhilarating day of exploring and driving will have you longing for a comfortable bed at the end of the day. Fortunately, Lugano’s top hotels offer a lovely retreat at day’s end. Choose from options ranging from budget to luxury.

Before this memorable day of your vacation comes to a close, treat your palate to a taste of Switzerland's delectable cuisine at one of Lugano's best restaurants. After a nice meal, enhance your vacation experience by enjoying the local nightlife or unwinding with a drink or two in the town’s most recommended bars.

Start your culinary exploration in Lugano by securing a reservation at Flamel. This renowned restaurant holds a Bib Gourmand award and offers an exceptional menu of contemporary and seasonal cuisine. Immerse yourself in the culinary delights of Lanchetta Lounge Bar & Pinsa. , a popular restaurant in Lugano. With a menu designed to delight, it ensures a dining experience that transcends the ordinary.

After your meal, keep the night alive at a bar like Il Fermento, known for its lively atmosphere. Bar Oops is another top recommendation that provides the perfect setting with well-crafted drinks and a welcoming ambiance.

As the night falls in Lugano, take a moment to savor the experiences of the day. Wash away your fatigue with a drink, or lie back and relax at your hotel, and look forward to another thrilling day of your multi-country journey across Europe.

On day 11, you will wake up in Florence with an entire day of wonders ahead of you! You still have 2 nights left in Florence before it’s time to get back on the road and continue your European tour across Italy, France, and Switzerland.

One place travelers keep coming back to in Florence is the magnificent Basilica Of Santa Croce In Florence. Around 28,544 visitors have rated this excellent church and travel destination an average of 4.7 out of 5 stars.

We also recommend you explore the amazing Piazza Della Signoria on this leg of your adventure in Italy. This attraction is a well-known public square that has an average rating of 4.8 out of 5 stars from around 66,956 travelers.

The remarkable Uffizi Gallery is known to be one of the best places to visit in Florence, and its average rating of 4.7 out of 5 stars from 61,794 traveler reviews is proof. Attracting more than 2,011,219 visitors in a single year, it's clear that the wonderful Uffizi Gallery is a perfect add-on to your itinerary.

Dive deeper into Florence by exploring the captivating Ponte Vecchio. With a stellar average rating of 4.7 out of 5 stars from 118,099 travelers, make sure this wonderful site is on your Florence exploration list!

As the sun dips under the horizon, freshen up and head out to discover the best dining spots in Florence. Check out our recommendations on where to wine and dine while seeing this marvelous destination in Italy in a new light. After dinner, head out to a bar to relax, mingle with the locals, and raise a toast to your unforgettable road trip vacation in Europe.

Treat yourself to a wonderful meal at Ditta Artigianale, a top-rated dining spot in Florence. If you're in the mood for something new, try Trattoria Da Burde, another premier location with a delectable menu. You might also want to book a table at Casa Toscana. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Florence.

Round off your dining experience by visiting Bar 50 Rosso, a prime location for a drink. Alternatively, explore the distinctive characteristics of Bitter Bar, a bar catering to every mood and preference. Archea Brewery likewise offers a unique atmosphere, perfect for a memorable night out.

Savor the moment and raise a toast to yet another amazing day of your vacation in Italy, France, and Switzerland! Enjoy your evening in Florence to the fullest by mingling with the locals at a bar, taking a stroll around the city center, or simply relaxing.

Wake up and see what day 12 of your great European road trip in Italy, France, and Switzerland has in store for you! You will be staying in Florence for 1 night before continuing your journey to the next destination.

Complement your beautiful day with a visit to a top-rated botanical garden and attraction in Florence — The Boboli Gardens. About 25,341 visitors have rated this attraction an average of 4.2 out of 5 stars.

The popular Cathedral Of Santa Maria Del Fiore is another top sight in Florence that locals and travelers often enjoy spending time at. This attraction is a well-loved church in the area, rated an average of 4.8 out of 5 stars by 76,359 visitors.

Central Market is a spectacular food market and highlight on travelers’ itineraries in Florence, earning an impressive average rating of 4.4 out of 5 stars from 43,100 enchanted visitors.

As the day moves along, be sure to make time to drop by the magnificent Galleria Dell'accademia. Because of its allure and charm, around 34,429 visitors have rated this attraction and art gallery an average of 4.6 out of 5 stars. More than 1,719,645 people visit this attraction each year, and today is your opportunity to be one of the lucky travelers to explore it.

Discover the allure of David. Echoing its popularity, 10,476 travelers have awarded this famous statue and sightseeing spot an impressive average rating of 4.8 out of 5 stars.

As the day unfolds, you’ll be delighted to find that the city of Florence boasts an array of restaurants and bars catering to every budget. Take this opportunity to sample the distinctive flavors of Italy.

Savor the flavors at Ristorante Buca Mario, a top pick for dinner tonight. Alternatively, Agricola Toscana beckons with its unique menu offerings. Also, consider Eataly Firenze. With its consistent customer satisfaction, it’s an excellent option for dining in Florence tonight.

After your delicious meal, get a taste of the vibrant nightlife with a visit to Gosh*, known for its inviting atmosphere. Antico Caffè Del Moro - Art Bar Firenze is another great option if you’re looking for a place to get the night started. Similarly, Quelo Bar provides a great setting to enjoy the night away.

Go to bed happy and look forward to a good night’s sleep as soon as your head hits the pillow. Your European tour continues tomorrow!

On day 13 of your multi-country road trip across Italy, France, and Switzerland, you will get a true taste of the freedom a self-drive vacation in Europe entails. In the evening, you’ll end up in Rome, where you will stay for 1 night.

After soaking in Florence’s unique atmosphere, jump into the car with a full heart and drive in the direction of your next destination: Vatican City, Vatican City. Expect your car journey to take a minimum of 3 hours 11 min. When you arrive in Vatican City, it's time to take a break from the road.

You'll enjoy easy access to the most remarkable sights in Vatican City, including the outstanding Vatican Museums. Having an average rating of 4.6 out of 5 stars in 133,310 reviews and welcoming more than 1,612,530 visitors each year, this fascinating art museum and attraction is one of the top travel destinations in the city.

Vatican City is also home to the captivating Sistine Chapel, a local chapel considered one of the highlights of the city. About 52,083 visitors have rated this incredible site with 4.7 out of 5 stars, proving its popularity.

The extraordinary Saint Peter's Square is another unforgettable place you can visit on this leg of your journey in Vatican City. This extraordinary square and tourist hot spot boasts a rating of 4.8 out of 5 stars from 38,954 travelers.

A trip to the wonderful St. Peter's Basilica will inspire you as it does to more than 11,000,000 travelers every year. Visitors have rated their experience at this amazing major basilica and attraction an average of 4.8 out of 5 stars in 131,043 reviews.

After a long day of driving and exploring, you’ll check in at a top-recommended hotel in Rome of your choice.

In the evening, prepare to be amazed by Rome’s regional flavors and culminate your day with a toast. We’ve curated a guide to the city’s culinary and nightlife hotspots to enhance your experience during your multi-country vacation in Italy, France, and Switzerland.

Don’t miss out on dining at Hotel de Russie, a top-rated dining destination in Rome. If you're in the mood to try something new, consider La Taverna Italiana, another top spot with a mouthwatering menu. You might also want to secure a reservation at The Parrot Bar. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Rome this evening.

Following your dinner, dive into the local bar culture at The Apartment Bar Roma. Enjoy this evening's relaxed ambiance with delightful drinks. Alternatively, go to Hotel Hassler Roma, the perfect place for those looking to experience the best of the nightlife.

Spend the evening looking over your itinerary for tomorrow and reminisce about what you’ve seen and done so far on your European road trip adventure. New experiences await!