14-Day Italy Self-Drive Road Trip With Itinerary from Brindisi traveling west to Taranto, Salerno, Rome, Naples, and Bari

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Ostuni white town skyline at sunset, Brindisi, Apulia southern Italy. Europe.
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Explore the best of Italy on a remarkable 14-day road trip! Combine exploration with relaxation on a self-drive tour featuring Brindisi, Taranto, Matera, Salerno, Ravello, Amalfi, Pompei, Rome, Caserta, Naples, Trani, Bari, and Polignano a Mare.

This perfectly planned road trip itinerary takes you through some of the best places to see in Italy. You will spend 2 nights in Brindisi, 1 night in Taranto, 2 nights in Salerno, 5 nights in Rome, 2 nights in Naples, and 1 night in Bari. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Brindisi, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Trevi Fountain and Colosseum are just a couple of the bucket-list attractions that await your discovery.

As you hit the open road and drive through Brindisi, Taranto, Matera, Salerno, Ravello, Amalfi, Pompei, Rome, Caserta, Naples, Trani, Bari, and Polignano a Mare, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.

Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!

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Driver’s age is 30 - 65
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Pick-up: 10:00
Drop-off: 10:00

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Day 1

Day 1

  • Brindisi - Arrival day
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  • Lungomare Regina Margherita
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Say hello to Brindisi! Your exciting road trip through Italy is just about to start. Navigating the top places to see in the region is a breeze with a car. The rental vehicle of your choice will be ready for pickup upon your arrival in the city. You will stay in Brindisi for 1 night before you continue your adventure!

Brindisi is a beautiful city with plenty to discover. Taking a stroll in the city center is a great alternative. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

When you're ready for some downtime, make your way to your chosen hotel. Check-in typically starts between 2 and 4 PM in Brindisi. Make yourself at home and unwind before heading out again.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Brindisi, it's often a good idea to reserve a table in advance.

Raise a toast to the start of your 14-day road trip in Italy!

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Day 2

Day 2

  • Brindisi
  • Taranto
  • More

Drive 72 km, 1 hour 21 min

  • Palazzo Granafei Nervegna (Brindisi)
  • San Giovanni al Sepolcro
  • Swabian Castle of Brindisi
  • More

Your itinerary for day 2 of your road trip in Italy includes 1 stop and features some of the highlights of Brindisi. At the end of the day, enjoy the comforts of a top-rated hotel in Taranto, where you'll spend 1 night.

At the end of the day, you will drive to Taranto, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Taranto. Enjoy a relaxing evening as you savor delicious local cuisine.

Head back to your accommodation in Taranto and get some rest to prepare for another magical day of your road trip in Italy.

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Day 3

Day 3

  • Taranto
  • Salerno
  • More

Drive 264 km, 3 hours 31 min

  • Monumento ai caduti
  • Piazza della Vittoria
  • Parco Scultura La Palomba
  • More

On day 3 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 2 destinations, including Taranto and Matera. When you’re not sightseeing, take time to relax at your chosen hotel in Salerno, where you’ll be staying for 2 nights.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Salerno. Salerno offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a day of adventure, treat yourself to an exquisite dinner at one of Salerno's best restaurants.

Raise your glass and celebrate another amazing day of your road trip in Italy!

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Day 4

Day 4

  • Salerno
  • More

Drive 144 km, 4 hours 9 min

  • Villa Rufolo
  • Villa Cimbrone Gardens
  • Amalfi Coast
  • Archaeological Park of Paestum
  • Tempio di Poseidone - Parco Archeologico di Paestum (SA)
  • More

Wake up to day 4 of your road trip in Italy. On this day, you’ll embark on an exciting expedition discovering the enchanting sights and activities of Ravello, Castiglione, Amalfi, and Paestum. With 1 night to stay in Salerno, we encourage you to seize the day and discover the unexplored beauty of the city’s surroundings!

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Salerno.

Salerno is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Salerno.

Head back to your accommodation in Salerno and get some rest to prepare for another magical day of your road trip in Italy.

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Day 5

Day 5

  • Salerno
  • Rome
  • More

Drive 276 km, 3 hours 41 min

  • Archaeological Park of Pompeii
  • Lupanar des esclaves
  • Teatro Grande
  • Amphitheatre of Pompeii
  • More

On day 5 of your road trip in Italy, your travel plans include 1 stop at the most scenic, wondrous, and interesting places in the region. Pompei are on today's agenda. In the evening, you’ll end up in Rome, where you will stay for 5 nights.

Whether you decide to get entrance tickets for all attractions or you prefer admiring from a distance, amazing experiences await on this day in Salerno.

When you’re done exploring for the day, you’ll drive to your hotel in Rome. Check in and relax before you head out to tour the city.

Indulge in a memorable dining experience at one of Rome's most popular restaurants, and connect with friendly locals for a true cultural experience.

Celebrate another amazing day of your road trip adventure in Italy!

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Day 6

Day 6

  • Rome
  • More

Drive 10 km, 55 min

  • Vatican Museums
  • Saint Peter's Square
  • Sistine Chapel
  • St Peter's Basilica
  • More

On day 6 of your road trip in Italy, you’ll start and end your day in Rome, but spend the day exploring what’s beyond the city. Since you still have 4 nights to spend in Rome, there’s no need to rush. Experience Vatican City to the fullest today with this curated day itinerary.

When you’re done exploring for the day, you’ll return to Rome and your accommodation.

Indulge in a memorable dining experience at one of Rome's most popular restaurants, and connect with friendly locals for a true cultural experience.

As the sun sets, rest up and recharge for the next leg of your road trip in Italy.

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Day 7

Day 7

  • Rome
  • More

Drive 3 km, 47 min

  • Trevi Fountain
  • Pantheon
  • Piazza Navona
  • Campo de' Fiori
  • Trastevere
  • More

You have 3 nights left in Rome. Take the opportunity to experience more of the best attractions and activities in the city.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Rome. Enjoy a relaxing evening as you savor delicious local cuisine.

Relax and look forward to more memorable moments to come!

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Day 8

Day 8

  • Rome
  • More

Drive 9 km, 49 min

  • Spanish Steps
  • Piazza di Spagna
  • Colosseum
  • Roman Forum
  • Via dei Condotti
  • More

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Rome. Enjoy a satisfying meal that will recharge you for tonight's adventures.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in Italy.

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Day 9

Day 9

  • Rome
  • More

Drive 12 km, 1 hour 4 min

  • Circus Maximus
  • Castel Sant'Angelo
  • piazza del Popolo
  • Villa Borghese
  • Via del Corso
  • More

Day 9 offers an itinerary packed with the best things to see in Brindisi. You’ll stay in Rome for 1 night more, offering you enough time to explore at a relaxed pace.

One of the most iconic spots you can visit today is Via del Corso. Allow yourself some time to explore this street and discover its unique quirks. You'll also find many of the best sightseeing spots nearby.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

Indulge in a memorable dining experience at one of Rome's most popular restaurants, and connect with friendly locals for a true cultural experience.

Savor another day of unforgettable experiences in Italy!

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Day 10

Day 10

  • Rome
  • Naples
  • More

Drive 242 km, 3 hours 13 min

  • Altare della Patria
  • Basilica di Santa Maria Maggiore
  • Baths of Caracalla
  • Palace of Caserta
  • More

Dive into day 10 of your remarkable road trip in Italy. Today you'll explore 2 destinations, including Rome and Caserta. At the end of the day, you’ll unwind at one of the finest accommodations in Naples, where you'll spend 2 nights.

At the end of the day, you will drive to Naples, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Naples, it's often a good idea to reserve a table in advance.

As the sun sets, rest up and recharge for the next leg of your road trip in Italy.

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Day 11

Day 11

  • Naples
  • More

Drive 12 km, 1 hour 2 min

  • Ovo Castle
  • Cappella Sansevero
  • Napoli Sotterranea Percorso Ufficiale
  • Via Toledo
  • Quartiere Spagnolo
  • More

You’ll stay in Naples for 1 night.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Naples, it's often a good idea to reserve a table in advance.

Raise your glass and celebrate another amazing day of your road trip in Italy!

Read more
Day 12

Day 12

  • Naples
  • Bari
  • More

Drive 274 km, 3 hours 39 min

  • piazza del Plebiscito
  • Castel Nuovo
  • Naples National Archaeological Museum
  • Villa Comunale
  • More

Experience an unparalleled adventure on day 12 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 2 places, which are Naples and Trani. At the end of the day, you will retreat to the hotel of your choice in Bari, where will spend 1 night.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Bari. Bari offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Bari. Enjoy a satisfying meal that will recharge you for tonight's adventures.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in Italy.

Read more
Day 13

Day 13

  • Bari
  • Brindisi
  • More

Drive 124 km, 2 hours 17 min

  • Basilica Cattedrale Metropolitana Primaziale San Sabino
  • Basilica San Nicola
  • Teatro Petruzzelli
  • Lama Monachile
  • Monumento a Domenico Modugno
  • More

Your itinerary for day 13 of your road trip in Italy includes 2 stops and features some of the highlights of Bari and Polignano a Mare. At the end of the day, enjoy the comforts of a top-rated hotel in Brindisi, where you'll spend 1 night.

When you’re done exploring for the day, you’ll drive to your hotel in Brindisi. Check in and relax before you head out to tour the city.

Brindisi is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Brindisi.

Relax and look forward to more memorable moments to come!

Read more
Day 14

Day 14

  • Brindisi - Departure day
  • More
  • The Monument To Virgil
  • More

Day 14 of your road trip in Italy is your departure day. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!

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How it works

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Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

We guarantee

Your trip is protected, personalized, and priced right. No surprises, no stress.

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