14-Day Italy Self-Drive Road Trip With Itinerary from Genoa to La Spezia, Florence, Siena, Rome, and Naples

Day 2 of your road trip across Italy promises a magnificent time exploring what to see in Genoa. You have 1 night left in Genoa. Take the opportunity to experience more of the best attractions and activities in the city.

Whether you decide to explore Genoa on foot, use public transport, or join a guided tour, there are a few attractions you don’t want to miss.

One of the most notable attractions included on the itinerary is Porto Antico. This history-steeped public square will help you start your sightseeing on top. Then, take a leisurely stroll to Aquarium Of Genoa and learn what makes this picture-perfect aquarium unique.

Throughout the day, make sure to take breaks to appreciate the surroundings. Next up, visit the beloved Chiesa Di San Pietro In Banchi. After exploring the church, head to Genoa Cathedral. This increasingly popular church is a highlight in Genoa. As your day continues, stop by Palazzo Podestà, known for its heritage-rich features. Lastly, don’t forget to check out the often recommended Via Garibaldi. Enjoy exploring this incredible street at your own pace.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

Genoa is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Genoa.

Make sure to reserve a table at Zeffirino, an iconic dining spot in Genoa. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Trattoria Vegia Zena, a popular restaurant in Genoa. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Trattoria delle Grazie, a hidden gem nestled in Genoa. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in Italy.

Experience an unparalleled adventure on day 3 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 2 places, which are Corniglia and Manarola. At the end of the day, you will retreat to the hotel of your choice in La Spezia, where will spend 2 nights.

After soaking in Genoa’s unique atmosphere, jump into the car with a full heart and drive in the direction of your next destination: Corniglia. Expect your car journey to take a minimum of 1 hour 45 min. When you arrive in Corniglia, it's time to take a break from the road.

One of our top recommendations for your sightseeing is Sentiero Azzurro. Spend some time admiring the eye-catching features of the hiking area before you continue to your next stop. Then, head to Cinque Terre National Park. This interesting national park is a traveler-favorite in the village.

It’s time to gear up for the next part of your road trip adventure. Under favorable conditions, your drive to Manarola may take around 15 min. Upon your arrival in Manarola, you’ll be greeted with the opportunity to do some sightseeing and exploring.

Savor the day by heading to Manarola Overlook Viewpoint, an often recommended observation deck that draws visitors from near and far.

When you’re done exploring for the day, you’ll drive to your hotel in La Spezia. Check in and relax before you head out to tour the city.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in La Spezia. Enjoy a relaxing evening as you savor delicious local cuisine.

Enjoy a delicious meal at The Colombaio Park, a highly-rated dining destination in La Spezia.

As the sun sets, rest up and recharge for the next leg of your road trip in Italy.

On day 4 of your road trip, you’ll start and end your day in La Spezia, where you have 1 night left to stay.

Riomaggiore’s wonders await as you prepare for another journey on the road, leaving the breathtaking surroundings of La Spezia behind. This drive usually takes around 20 min. Riomaggiore welcomes you with a multitude of unique vacation experiences.

Our first attraction recommendation in Riomaggiore is Nostra Signora Di Montenero, an up-and-coming church that draws attention for its visually striking features.

Time flies when you're having fun! But don't forget to stop for a bit to eat and drink between your adventures. When you're rested and recharged, head to Castle Of Riomaggiore, a locally appreciated castle that offers a unique experience.

When you’re done exploring for the day, you’ll return to La Spezia and your accommodation.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in La Spezia. Enjoy a satisfying meal that will recharge you for tonight's adventures.

As the sun sets, rest up and recharge for the next leg of your road trip in Italy.

On day 5 of your road trip in Italy, your travel plans include 1 stop at the most scenic, wondrous, and interesting places in the region. Florence are on today's agenda. In the evening, you’ll end up in Florence, where you will stay for 2 nights.

Throughout the day, make sure to take breaks to appreciate the surroundings.

It’s time to gear up for the next part of your road trip adventure. Under favorable conditions, your drive to Florence may take around 1 hour 53 min. Upon your arrival in Florence, you’ll be greeted with the opportunity to do some sightseeing and exploring.

Savor the day by heading to Bargello National Museum, an increasingly popular museum that draws visitors from near and far. When you're done, continue to Palazzo Vecchio, where you can soak in the romantic surroundings.

Next, explore Uffizi Gallery, yet another top-rated place to see in the area. After the art gallery, make time to go to Ponte Vecchio. This romantic historical landmark is well worth the visit. Lastly, head to Piazza Della Signoria, a top-rated public square you won’t want to miss.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Florence. Florence offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Florence, it's often a good idea to reserve a table in advance.

Enjoy a lovely meal at Ristorante Oliviero 1962, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Di Poneta Novoli is another top choice with a popular menu. You could also check for a table at Caffe San Firenze. As an establishment that consistently gains high praises from customers, it’s an ideal choice in Florence tonight.

Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, Manifattura stands out as an excellent choice for a post-dinner cocktail. Alternatively, Se·sto On Arno Rooftop Bar offers an ideal atmosphere to enjoy the pleasures of the night. Il Vinile is also a great option that provides a perfect setting for a relaxing evening.

Get a good night's sleep and look forward to another great day on the road in Italy!

Day 6 of your road trip will take you to the best attractions Florence has to offer. Cherish the 1 night you have left in the city and use the provided itinerary to discover what to see in Florence.

Next, go to Galleria Dell'accademia.

After visiting David and Galleria Dell'accademia, have a stroll along Florence's streets and take in the local charm. Continue your sightseeing by heading to Cathedral Of Santa Maria Del Fiore. This enchanting church offers a unique experience. Basilica Of Santa Croce In Florence is another noteworthy attraction worthwhile a visit. End your self-guided sightseeing tour on top with a visit to Piazzale Michelangelo, one of the most visually striking places to visit in Florence.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Florence, it's often a good idea to reserve a table in advance.

Savor the flavors at Ditta Artigianale, a top pick for dinner tonight. Alternatively, Trattoria Da Burde beckons with its unique menu offerings. Also, consider Casa Toscana. With its consistent customer satisfaction, it’s an excellent option for dining in Florence tonight.

Cap off your dinner by heading to Bar 50 Rosso, ideal for a leisurely evening with a drink in hand. Bitter Bar is another bar that offers an enjoyable setting. Similarly, Archea Brewery is also a popular place to go on a night out, perfect for relaxing and socializing.

Head back to your accommodation in Florence and get some rest to prepare for another magical day of your road trip in Italy.

Your itinerary for day 7 of your road trip in Italy includes 1 stop and features some of the highlights of Siena. At the end of the day, enjoy the comforts of a top-rated hotel in Siena, where you'll spend 1 night.

Set your GPS to Siena and hit the road. Expect a journey of approximately 1 hour 8 min without stops. Soak in the beautiful landscapes as you drive and look forward to exploring your next destination. Siena beckons with new experiences!

When you're ready for some sights, head to Basilica Of San Domenico, an increasingly popular church in Siena. Explore its stunning features at your own pace before you continue your journey to your next attraction, Siena Cathedral. This locally renowned church is a top recommendation in the area.

When you’re ready to explore more, Pubblico Palace is an excellent choice. Spend some time discovering what some claim to be the most culturally significant palace in the region. Next, continue your sightseeing at the top-rated Piazza Del Campo and discover what makes this public square unique. If you’re up for one more stop in the city, head to Tower Of Mangia, an UNESCO world heritage-listed monument many travelers find the visit worthwhile.

At the end of the day, you will drive to Siena, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

Indulge in a memorable dining experience at one of Siena's most popular restaurants, and connect with friendly locals for a true cultural experience.

Savor the flavors at Enoteca I Terzi, a top pick for dinner tonight. Alternatively, Ristorante Tar-Tufo beckons with its unique menu offerings. Also, consider Antica Trattoria Papei. With its consistent customer satisfaction, it’s an excellent option for dining in Siena tonight.

Following your dinner, dive into the local bar culture at Meet Life Cafè. Enjoy this evening's relaxed ambiance with delightful drinks. Alternatively, go to Maudit Pub, the perfect place for those looking to experience the best of the nightlife. Similarly, Bar Impero Siena provides excellent drinks and a great atmosphere, ensuring a memorable night out.

Say good night to Siena and look forward to another great day of your road trip in Italy!

Dive into day 8 of your remarkable road trip in Italy. Today you'll explore 1 destination, including Rome. At the end of the day, you’ll unwind at one of the finest accommodations in Rome, where you'll spend 3 nights.

Continue your road trip and head to your next destination, Rome. This car ride takes around 2 hours 36 min.

Spend your afternoon discovering Castel Sant'angelo, an astonishing castle known for its history-steeped features. Next, continue your sightseeing at Spanish Steps, a widely recognized public square.

If you're starting to feel hungry, this is a great time for a break at a nearby restaurant or cafe. When you're ready for more, stop by Piazza Di Spagna and uncover the details of this visually striking public square. Make sure to also explore Trevi Fountain, a timeless monument. For your last stop, consider Pantheon, a culturally significant monument that many travelers find worth the detour.

When you’re done exploring for the day, you’ll drive to your hotel in Rome. Check in and relax before you head out to tour the city.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Rome. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Treat yourself to a delicious dinner at La Bottega Roma, an excellent option for tonight's dining. Looking for something different? Pasta In Corso offers a tantalizing alternative with its diverse menu. And don’t miss Trattoria Vecchia Roma. Known for great service, it’s a fantastic choice for tonight in Rome.

Cap off your dinner by heading to La Botticella Of Poggi Giovanni, ideal for a leisurely evening with a drink in hand. Almalu Trastevere is another bar that offers an enjoyable setting. Similarly, Bar Viminale Di Pepi Maurilio is also a popular place to go on a night out, perfect for relaxing and socializing.

Raise your glass and celebrate another amazing day of your road trip in Italy!

On day 9 of your road trip, you’ll start and end your day in Rome, where you still have 2 nights left. You'll spend part of the day exploring places of interest outside the immediate city, including Vatican City and Rome.

A top thing to do today is to explore Trastevere, a must-see neighborhood in Vatican City. It's the perfect starting point for touring the top attractions in the area.

Start your day at Campo De' Fiori. This instagrammable public square is a spectacular place to see in Rome. Then, wander over to Piazza Navona. If visually striking sites excite you, this public square will be right up your alley.

Once you're ready to continue your road trip, it's time to buckle up and drive towards Vatican City, eagerly anticipating your arrival in Vatican City. This drive usually takes around 12 min, without any stops or traffic disruptions.

One of our top recommendations for your sightseeing is Vatican Museums. Then, head to Sistine Chapel. This widely recognized chapel is a traveler-favorite in the city.

If you're keen to see more, continue to St. Peter's Basilica. Feed your curiosity by learning something new about the major basilica.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Rome.

Indulge in a memorable dining experience at one of Rome's most popular restaurants, and connect with friendly locals for a true cultural experience.

Make sure to reserve a table at RomAntica, an iconic dining spot in Rome. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Coso Ristorante, a popular restaurant in Rome. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of DEROMA - Farine Romane, a hidden gem nestled in Rome. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

After your meal, keep the night alive at a bar like Sant' Eustachio Caffè, known for its lively atmosphere. Yellowsquare Rome is another top recommendation that provides the perfect setting with well-crafted drinks and a welcoming ambiance. Similarly, Caffè Portofino offers an excellent atmosphere for those looking to amp up the evening.

Relax and look forward to more memorable moments to come!

On day 10 of your road trip, you will have an entire day to discover what to see in Rome. You’ll stay in Rome for 1 night.

Colosseum is must-visit archeological site and a great option for a daytime tour of the area. Continue your journey to Arch Of Constantine, a beloved monument, located just a leisurely stroll away. Next, head to Roman Forum, an UNESCO world heritage-listed archeological site, also available for your discovery today.

Each stop on today’s itinerary promises to leave you with lasting memories and a deeper appreciation for Rome. When you're ready, let your sightseeing route take you to the interesting Capitoline Hill. If you’re looking for more, Capitoline Museums is also a popular attraction that is worthwhile a visit. Lastly, don’t miss Altare Della Patria, a place of culturally significant interest in the city.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

After a day of adventure, treat yourself to an exquisite dinner at one of Rome's best restaurants.

Enjoy a lovely meal at Hotel de Russie, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, La Taverna Italiana is another top choice with a popular menu. You could also check for a table at The Parrot Bar. As an establishment that consistently gains high praises from customers, it’s an ideal choice in Rome tonight.

Continue your lively evening at The Apartment Bar Roma, a perfect place for winding down or revving up the night, depending on which mood you’re in. Hotel Hassler Roma is another excellent bar that offers a great selection of drinks to suit any mood.

Celebrate another amazing day of your road trip adventure in Italy!

On day 11 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, including Naples. When you’re not sightseeing, take time to relax at your chosen hotel in Naples, where you’ll be staying for 2 nights.

When you’ve had your share of Rome, prepare for your next destination. Admire the views and listen to some good music as you drive in the direction of Naples. Your travel time is around 2 hours 32 min.

For a more meaningful self-guided tour of the city's best attractions, visit Castel Sant'elmo, a locally renowned castle that is sure to impress. Take in the surroundings and enjoy the freedom of exploring at your own pace before you continue your journey. Next, head to Naples National Archaeological Museum and admire its history-steeped features.

When you’re ready, continue to Cappella Sansevero, an interesting museum beloved by locals and tourists alike. Don't miss out on Spaccanapoli, another highlight of the area that promises a memorable visit.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Naples. Naples offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a day of adventure, treat yourself to an exquisite dinner at one of Naples's best restaurants.

Treat yourself to a wonderful meal at L'Oca Nera Irish Pub, a top-rated dining spot in Naples. If you're in the mood for something new, try Mimì alla Ferrovia, another premier location with a delectable menu. You might also want to book a table at Spuzzulè Winebar. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Naples.

After your delicious meal, get a taste of the vibrant nightlife with a visit to Happening Cocktail Bar, known for its inviting atmosphere. Shanti Art Musik Bar is another great option if you’re looking for a place to get the night started. Similarly, Gran Caffè Gambrinus provides a great setting to enjoy the night away.

Raise your glass to another unforgettable day in Italy!

On day 12 of your road trip, you'll get the chance to experience Pompei, Ercolano, and Ottaviano. At the end of the day, you'll drive back to Naples, where you still have 1 night left to stay.

Pompei is brimming with adventures.

When you’re ready to jump back into the car and say goodbye to Naples, you’ll hit the road in the direction of Pompei. This drive usually takes around 27 min.

Archaeological Park Of Pompeii is a locally renowned archeological site we recommend visiting today. Discover its historic features before continuing your self-guided tour.

After soaking in Pompei’s unique atmosphere, jump into the car with a full heart and drive in the direction of your next destination: Ercolano. Expect your car journey to take a minimum of 20 min. When you arrive in Ercolano, it's time to take a break from the road.

For a more meaningful self-guided tour of the town's best attractions, visit Archaeological Park Of Herculaneum, a curiosity-inducing archeological site that is sure to impress. Take in the surroundings and enjoy the freedom of exploring at your own pace before you continue your journey.

It’s time to gear up for the next part of your road trip adventure. Under favorable conditions, your drive to Ottaviano may take around 26 min. Upon your arrival in Ottaviano, you’ll be greeted with the opportunity to do some sightseeing and exploring.

Our first attraction recommendation in Ottaviano is Mount Vesuvius, a frequently visited volcano that draws attention for its enchanting features.

When you’re done exploring for the day, you’ll return to Naples and your accommodation.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Naples, it's often a good idea to reserve a table in advance.

Treat yourself to a delightful dinner at Antica Pizzeria Di Matteo, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Mercure Napoli Centro Angioino? It's another excellent option with a diverse menu. Consider reserving a table at La Lazzara Trattoria e Pizzeria as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Naples.

After savoring a delicious meal, step into the vibrant nightlife at Archivio Storico - Cocktail Bar & Wonderfood, where the evening is just getting started. In the same way, Archeobar offers a unique charm perfect for experiencing the local bar scene in Naples. Babette Pub is another top-recommended bar that is sure to get you into the mood for some dancing and celebrating.

Head back to your accommodation in Naples and get some rest to prepare for another magical day of your road trip in Italy.

Experience an unparalleled adventure on day 13 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 place, which are Pisa. At the end of the day, you will retreat to the hotel of your choice in Genoa, where will spend 1 night.

Fasten your seatbelt and make your way to your next stop — Pisa, home to many well-known sights in the region. Keep in mind that your travel time from Naples to Pisa may take around 5 hours 35 min without traffic disruptions. Upon arrival in Pisa, we highly recommend checking out some of the top attractions.

Leaning Tower Of Pisa is a wondrous monument we recommend visiting today. Discover its culturally significant features before continuing your self-guided tour to Museo Dell'opera Del Duomo, a photogenic museum that’s well-regarded in the area.

Next, stop by Porta Nuova, a photogenic monument.

At the end of the day, you will drive to Genoa, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

Genoa is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Genoa.

Make sure to reserve a table at Osteria Sant'Ilario, an iconic dining spot in Genoa. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of La Cialtroneria, a popular restaurant in Genoa. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Manhattan Bar, a hidden gem nestled in Genoa. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Celebrate another amazing day of your road trip adventure in Italy!