Travel packages in Italy

Road trips in Italy

14-Day Italy Self-Drive Road Trip With Itinerary from Rome to Salerno, Naples, Pescara, Perugia, Venice, and Florence and surrounding area

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Photo of piazza de spagna in Rome, Italy.

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Experience the freedom of the open road on an unforgettable 14-day road trip in Italy! Embark on a self-drive tour that caters to every traveler, featuring destinations like Rome, Salerno, Pompei, Ercolano, Naples, Caserta, Pescara, Santa Maria degli Angeli, Perugia, Bologna, Padua, Venice, and Florence.

This perfectly planned road trip itinerary takes you through some of the best places to see in Italy. You will spend 5 nights in Rome, 1 night in Salerno, 2 nights in Naples, 1 night in Pescara, 1 night in Perugia, 1 night in Venice, and 2 nights in Florence. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Rome, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Trevi Fountain and Colosseum are just a couple of the bucket-list attractions that await your discovery.

As you hit the open road and drive through Rome, Salerno, Pompei, Ercolano, Naples, Caserta, Pescara, Santa Maria degli Angeli, Perugia, Bologna, Padua, Venice, and Florence, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.

Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!

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Driver’s age is 30 - 65

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Pick-up: 10:00

Drop-off: 10:00

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Day 1

Rome - Arrival day
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Altare della Patria
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Welcome to Rome, the perfect starting point for your road trip in Italy! Pick up your rental car and let the adventure begin. You will spend 4 nights discovering what to see in Rome before embarking on the next leg of your journey.

Rome is a beautiful city with plenty to discover. Taking a stroll in the city center is a great alternative. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Find your way to your hotel in Rome. We recommend choosing a hotel in a central location for easy exploring. Check-in typically starts between 2 and 4 PM at hotels in Italy. Settle in and make plans for the evening.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Rome, it's often a good idea to reserve a table in advance.

Raise a toast to the start of your 14-day road trip in Italy!

Day 2

Rome
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Drive 5 km, 1 hour 6 min

Colosseum
Roman Forum
Pantheon
Piazza Navona
Campo de' Fiori
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Day 2 offers an itinerary packed with the best things to see in Rome. You’ll stay in Rome for 3 nights more, offering you enough time to explore at a relaxed pace.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

After a day of adventure, treat yourself to an exquisite dinner at one of Rome's best restaurants.

Relax and recharge in preparation for another adventurous day in Italy!

Day 3

Rome
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Drive 11 km, 57 min

Spanish Steps
Piazza di Spagna
Trevi Fountain
Basilica di Santa Maria Maggiore
Archbasilica of St. John Lateran
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You have 2 nights left in Rome. Take the opportunity to experience more of the best attractions and activities in the city.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

Rome is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Rome.

As the sun sets, rest up and recharge for the next leg of your road trip in Italy.

Day 4

Rome
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Drive 12 km, 54 min

Villa Borghese
Passeggiata del Pincio
piazza del Popolo
Castel Sant'Angelo
Circus Maximus
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You’ll stay in Rome for 1 night.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Rome. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Take some time to reflect on your day and savor another beautiful night in Italy.

Day 5

Rome
Salerno
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Drive 354 km, 4 hours 20 min

Archaeological Park of Paestum
Tempio di Poseidone - Parco Archeologico di Paestum (SA)
Cattedrale di Santa Maria degli Angeli, San Matteo e San Gregorio VII
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Your itinerary for day 5 of your road trip in Italy includes 2 stops and features some of the highlights of Paestum and Salerno. At the end of the day, enjoy the comforts of a top-rated hotel in Salerno, where you'll spend 1 night.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Salerno. Salerno offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

Salerno is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Salerno.

Relax and recharge in preparation for another adventurous day in Italy!

Day 6

Salerno
Naples
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Drive 85 km, 2 hours 29 min

Archaeological Park of Pompeii
Temple of Venus
Amphitheatre of Pompeii
Archaeological Park of Herculaneum
Vesuvio National Park
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Dive into day 6 of your remarkable road trip in Italy. Today you'll explore 2 destinations, including Pompei and Ercolano. At the end of the day, you’ll unwind at one of the finest accommodations in Naples, where you'll spend 2 nights.

Throughout the day, make sure to take breaks to appreciate the surroundings.

When you’re done exploring for the day, you’ll drive to your hotel in Naples. Check in and relax before you head out to tour the city.

Indulge in a memorable dining experience at one of Naples's most popular restaurants, and connect with friendly locals for a true cultural experience.

Say good night to Naples and look forward to another great day of your road trip in Italy!

Day 7

Naples
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Drive 15 km, 1 hour 8 min

Castel Sant'Elmo
Naples National Archaeological Museum
Cappella Sansevero
Napoli Sotterranea Percorso Ufficiale
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Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Naples, it's often a good idea to reserve a table in advance.

Head back to your accommodation in Naples and get some rest to prepare for another magical day of your road trip in Italy.

Day 8

Naples
Pescara
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Drive 305 km, 4 hours 12 min

piazza del Plebiscito
Ovo Castle
Palace of Caserta
Giardini Reali - Parco Reggia di Caserta
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Experience an unparalleled adventure on day 8 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 2 places, which are Naples and Caserta. At the end of the day, you will retreat to the hotel of your choice in Pescara, where will spend 1 night.

At the end of the day, you will drive to Pescara, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Pescara. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Relax and look forward to more memorable moments to come!

Day 9

Pescara
Perugia
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Drive 256 km, 3 hours 40 min

Basilica di Santa Chiara
Basilica of San Francesco d'Assisi
Basilica of Santa Maria degli Angeli
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On day 9 of your road trip in Italy, your travel plans include 1 stop at the most scenic, wondrous, and interesting places in the region. Santa Maria degli Angeli are on today's agenda. In the evening, you’ll end up in Perugia, where you will stay for 1 night.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Perugia. Perugia offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Perugia, it's often a good idea to reserve a table in advance.

Take some time to reflect on your day and savor another beautiful night in Italy.

Day 10

Perugia
Venice
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Drive 409 km, 5 hours 17 min

Piazza Maggiore
Prato della Valle
The Basilica of St Anthony
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On day 10 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 2 destinations, including Bologna and Padua. When you’re not sightseeing, take time to relax at your chosen hotel in Venice, where you’ll be staying for 1 night.

When you’re done exploring for the day, you’ll drive to your hotel in Venice. Check in and relax before you head out to tour the city.

After a day of adventure, treat yourself to an exquisite dinner at one of Venice's best restaurants.

Savor another day of unforgettable experiences in Italy!

Day 11

Venice
Florence
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Drive 260 km, 3 hours 15 min

Rialto Bridge
Teatro La Fenice
Piazza San Marco
Doge's Palace
Bridge of Sighs
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Your itinerary for day 11 of your road trip in Italy includes 1 stop and features some of the highlights of Venice. At the end of the day, enjoy the comforts of a top-rated hotel in Florence, where you'll spend 2 nights.

At the end of the day, you will drive to Florence, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Florence. Enjoy a relaxing evening as you savor delicious local cuisine.

Raise your glass and celebrate another amazing day of your road trip in Italy!

Day 12

Florence
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Drive 4 km, 1 hour 6 min

piazzale Michelangelo
Uffizi Gallery
Ponte Vecchio
piazza della Signoria
Cathedral of Santa Maria del Fiore
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Day 12 offers an itinerary packed with the best things to see in Rome. You’ll stay in Florence for 1 night more, offering you enough time to explore at a relaxed pace.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

Indulge in a memorable dining experience at one of Florence's most popular restaurants, and connect with friendly locals for a true cultural experience.

Raise your glass and celebrate another amazing day of your road trip in Italy!

Day 13

Florence
Rome
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Drive 285 km, 3 hours 57 min

Sistine Chapel
St Peter's Basilica
Saint Peter's Square
Vatican Museums
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Dive into day 13 of your remarkable road trip in Italy. Today you'll explore 1 destination, including Vatican City. At the end of the day, you’ll unwind at one of the finest accommodations in Rome, where you'll spend 1 night.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Rome. Rome offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

Rome is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Rome.

Raise your glass to another unforgettable day in Italy!

Day 14

Rome - Departure day
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largo di Torre Argentina
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Day 14 of your road trip in Italy is your departure day. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

Browse through boutiques to find unique and stylish fashion pieces to take home.

Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!

How it works

Book your journey with Europe’s biggest travel platform—expert itineraries, instant confirmation, and full flexibility with 24/7 support.

Secure your spot

Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.

Get instant confirmation

Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.

Personalize your itinerary

Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.

Easily make changes

Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.

Enjoy seamless planning

With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.

Explore with confidence

From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

Secure your spot

Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.

Get instant confirmation

Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.

Personalize your itinerary

Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.

Easily make changes

Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.

Enjoy seamless planning

With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.

Explore with confidence

From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

We guarantee

Your trip is protected, personalized, and priced right. No surprises, no stress.

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