14-Day Italy Self-Drive Road Trip With Itinerary from Rome traveling west to Siena, Venice, Verona, Milan, Genoa, and Florence

On day 2 of your road trip, you will have an entire day to discover what to see in Rome. You’ll stay in Rome for 2 nights.

Whatever your travel style is, Castel Sant'angelo is an essential stop in Rome. This spectacular castle provides an insightful glimpse into the city's identity. Next, discover Piazza Navona, a romantic public square, promising a delightful encounter.

Continue your sightseeing with a visit to Pantheon, a globally renowned monument. When you’re done, don’t forget to make a stop at the wondrous Roman Forum. Round off your day at Colosseum, another gem in Rome with picture-perfect features to discover.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

Indulge in a memorable dining experience at one of Rome's most popular restaurants, and connect with friendly locals for a true cultural experience.

Dive into a culinary adventure like no other in Rome by booking a table at La Pergola. This popular restaurant holds 3 Michelin star and offers an exceptional menu of mediterranean and contemporary cuisine. For another dining option, venture to Il Pagliaccio, celebrated for its delectable creative and innovative menu. This acclaimed 2-star Michelin-recipient consistently leaves guests satisfied, ensuring an essential addition to your holiday itinerary. Seeking an alternative? Discover Enoteca La Torre, a top local restaurant known for its tantalizing mediterranean and creative menu. With a 2-star Michelin recognition, it promises an exceptional dining experience not to be missed.

Explore the vibrant nightlife at Sant' Eustachio Caffè after your meal, a hub for lively evenings and memorable moments. Or, head to Yellowsquare Rome for a great selection of flavorful drinks and a charming setting. Furthermore, Caffè Portofino is perfect for those looking to extend their night with a touch of local flavor.

Take some time to reflect on your day and savor another beautiful night in Italy.

Day 3 of your road trip across Italy promises a magnificent time exploring what to see in Rome. You have 1 night left in Rome. Take the opportunity to experience more of the best attractions and activities in the city.

Whether you decide to explore Rome on foot, use public transport, or join a guided tour, there are a few attractions you don’t want to miss.

Trevi Fountain is must-visit monument and a great option for a daytime tour of the area. Continue your journey to Piazza Di Spagna, a globally renowned public square, located just a leisurely stroll away. Next, head to Spanish Steps, an enchanting public square, also available for your discovery today.

Each stop on today’s itinerary promises to leave you with lasting memories and a deeper appreciation for Rome. When you're ready, let your sightseeing route take you to the astonishing Piazza Del Popolo. If you’re looking for more, Villa Borghese is also a spectacular attraction that is worthwhile a visit.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

For an unforgettable shopping experience, visit Via del Corso, the top shopping destination in Rome. Browse local shops and stores, each offering delightful surprises. Find unique souvenirs or items to take home. After shopping, explore what Via del Corso has to offer, including attractions, essential services, and vibrant community activities.

Rome is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Rome.

Enjoy a delicious meal at Hotel de Russie, a highly-rated dining destination in Rome. If you're eager to try something different, consider La Taverna Italiana, another top spot with a tantalizing menu. You might also want to secure a reservation at The Parrot Bar. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Rome this evening.

Let the evening flow smoothly from dinner to drinks at The Apartment Bar Roma, a top-rated bar in the area. For other recommendations, Hotel Hassler Roma provides a perfect setting for rounding out your night with style and great drinks.

Say good night to Rome and look forward to another great day of your road trip in Italy!

Dive into day 4 of your remarkable road trip in Italy. Today you'll explore 1 destination, including Vatican City. At the end of the day, you’ll unwind at one of the finest accommodations in Siena, where you'll spend 1 night.

It’s time to gear up for the next part of your road trip adventure. Set course for Vatican City! Under favorable conditions, your drive to Vatican City may take around 11 min. Upon your arrival in Vatican City, you’ll be greeted with the opportunity to do some sightseeing and exploring.

One of our top recommendations for your sightseeing is St. Peter's Basilica. Then, head to Sistine Chapel. This extraordinary chapel is a traveler-favorite in the city.

If you're keen to see more, continue to Saint Peter's Square. Feed your curiosity by learning something new about the square. Next, take your journey to Vatican Museums, a globally renowned art museum.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Siena. Siena offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Siena, it's often a good idea to reserve a table in advance.

Make sure to reserve a table at Enoteca I Terzi, an iconic dining spot in Siena. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Ristorante Tar-Tufo, a popular restaurant in Siena. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Antica Trattoria Papei, a hidden gem nestled in Siena. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

To truly maximize your evening out, consider visiting Meet Life Cafè after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to Maudit Pub, another bar with an inviting ambiance. Similarly, Bar Impero Siena also offers a great atmosphere, ensuring a night filled with enjoyment and relaxation.

Say good night to Siena and look forward to another great day of your road trip in Italy!

Your itinerary for day 5 of your road trip in Italy includes 2 stops and features some of the highlights of Siena and Bologna. At the end of the day, enjoy the comforts of a top-rated hotel in Venice, where you'll spend 1 night.

Make time for Piazza Del Campo, a spectacular public square that is worthwhile a visit in the city. Nearby, you’ll find Pubblico Palace, enchanting visitors with its historic appeal. Continue your exploration at Siena Cathedral. This church is one of the city’s most well-known spots.

Continue your road trip and head to your next destination, Bologna. This car ride takes around 2 hours 9 min.

For a more meaningful self-guided tour of the city's best attractions, visit Porta Galliera, a worthwhile monument that is sure to impress. Take in the surroundings and enjoy the freedom of exploring at your own pace before you continue your journey.

When you’re done exploring for the day, you’ll drive to your hotel in Venice. Check in and relax before you head out to tour the city.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Venice. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Dive into a culinary adventure like no other in Venice by booking a table at Local. This popular restaurant holds 1 Michelin star and offers an exceptional menu of contemporary cuisine. For another dining option, venture to Wistèria, celebrated for its delectable contemporary and venetian menu. This acclaimed 1-star Michelin-recipient consistently leaves guests satisfied, ensuring an essential addition to your holiday itinerary. Seeking an alternative? Discover Quadri, a top local restaurant known for its tantalizing modern menu. With a 1-star Michelin recognition, it promises an exceptional dining experience not to be missed.

Continue your evening by exploring the vibrant nightlife scene at Al Parlamento, a prime destination for a thrilling night out. Also, don’t forget to check out The Caffe Rosso, a bar that offers unique local touches. Likewise, Adagio provides an excellent alternative for a fun evening.

Raise your glass to another unforgettable day in Italy!

Experience an unparalleled adventure on day 6 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 place, which are Venice. At the end of the day, you will retreat to the hotel of your choice in Verona, where will spend 1 night.

Let Rialto Bridge set the tone for the day. Spend some time admiring this history-steeped historical landmark before continuing your journey. Piazza San Marco is your next stop. This wondrous public square is one of the best-rated sights in Venice.

Consider grabbing some lunch or a light snack to keep your energy going. Beyond the above-mentioned attractions, today is also the perfect time to visit St Mark's Basilica. This enchanting church is a sight to behold. To round off your sightseeing experience, visit Doge's Palace and Bridge Of Sighs.

At the end of the day, you will drive to Verona, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Verona. Enjoy a relaxing evening as you savor delicious local cuisine.

Treat yourself to an extraordinary dining experience at Osteria Mondo d'Oro, a Bib Gourmand restaurant offering an incredible italian and seasonal menu. Alternatively, if your taste buds call for something different, Casa Perbellini 12 Apostoli is one of the best restaurants for creative and contemporary cuisine in Verona. This 2-star Michelin-awardee earns consistently high praises from guests. We also recommend checking out the menu at Il Desco. As a top-rated establishment with 1 Michelin star, it is an ideal choice for italian contemporary cuisine in the city.

Explore the vibrant nightlife at Archivio after your meal, a hub for lively evenings and memorable moments. Or, head to La Segreteria Café for a great selection of flavorful drinks and a charming setting. Furthermore, Grande Giove Cocktail Bar is perfect for those looking to extend their night with a touch of local flavor.

Relax and look forward to more memorable moments to come!

Day 8 of your road trip will take you to the best attractions Milan has to offer. Cherish the 1 night you have left in the city and use the provided itinerary to discover what to see in Milan.

Let Arch Of Peace set the tone for the day. Spend some time admiring this picture-perfect monument before continuing your journey. Museo Della Scienza E Della Tecnologia "leonardo Da Vinci" is your next stop. This captivating museum is one of the best-rated sights in Milan.

Consider grabbing some lunch or a light snack to keep your energy going. Beyond the above-mentioned attractions, today is also the perfect time to visit Parco Sempione. This eye-catching park is a sight to behold. To round off your sightseeing experience, visit Sforzesco Castle Art Library and Piazza Gae Aulenti.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Milan. Enjoy a relaxing evening as you savor delicious local cuisine.

Treat yourself to a delicious dinner at Dessert Bar Milano, an excellent option for tonight's dining. Looking for something different? Radisson Blu Hotel Milan offers a tantalizing alternative with its diverse menu. And don’t miss Ristorante Qui Si Mangia. Known for great service, it’s a fantastic choice for tonight in Milan.

Keep the excitement of the evening going by visiting a bar or two. Kilburn Cocktail Bar Milano is an excellent place to start. You could also check out Bar Frida, offering a different kind of charm. A last recommendation for the day is The Friends Pub Milano. This bar promises an enjoyable experience with tasty drinks and a vibrant setting.

Get a good night's sleep and look forward to another great day on the road in Italy!

On day 9 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, including Milan. When you’re not sightseeing, take time to relax at your chosen hotel in Genoa, where you’ll be staying for 1 night.

Cathedral Square is an ideal stop early in the day. This curiosity-inducing public square is a must-visit in the city. When you’re ready for your next discovery, continue to Duomo Di Milano Museum, which may be one of the most symbolic places you will experience today.

One of the best things about exploring Milan on a self-guided tour is that you set the pace. There’s plenty of time for detours and discovering hidden gems. When you’re ready for your next stop, make your way to Galleria Vittorio Emanuele Ii, an astonishing shopping mall in the city. If you’re up for more discoveries, don’t forget to reserve some time for La Scala and Pinacoteca Di Brera.

When you’re done exploring for the day, you’ll drive to your hotel in Genoa. Check in and relax before you head out to tour the city.

After a day of adventure, treat yourself to an exquisite dinner at one of Genoa's best restaurants.

Have a memorable dining experience in Genoa by booking a table at San Giorgio, a 1-star Michelin restaurant presenting an exceptional modern and ligurian menu. For a different culinary experience in Genoa, The Cook shines as one of the top destinations, known for its delicious modern cuisine. This 1-star Michelin-awardee consistently earns high praises, making it a must-visit addition to your holiday experience. If you're looking for an alternative, Il Marin is known as a top local spot in Genoa for its delicious seafood and contemporary cuisine. This 1-star Michelin awardee is a highly recommended choice for an unforgettable meal.

Unwind after your meal by stepping into Scurreria Beer & Bagel. This venue is celebrated for its extensive drink selections and cozy vibes. Alternatively, La Lepre offers a dynamic and energetic atmosphere for a glass or two. Don’t overlook Bar Pisacane Iii, another top-rated bar in the area.

Raise your glass and celebrate another amazing day of your road trip in Italy!

Dive into day 10 of your remarkable road trip in Italy. Today you'll explore 2 destinations, including Genoa and Pisa. At the end of the day, you’ll unwind at one of the finest accommodations in Florence, where you'll spend 3 nights.

Start your day at Piazza De Ferrari. This enchanting public square is a popular place to see in Genoa. Then, wander over to Aquarium Of Genoa. If breathtaking sites excite you, this aquarium will be right up your alley.

Fasten your seatbelt and make your way to your next stop — Pisa, home to many well-known sights in the region. Keep in mind that your travel time from Genoa to Pisa may take around 2 hours 5 min without traffic disruptions. Upon arrival in Pisa, we highly recommend checking out some of the top attractions.

Set out on a self-guided sightseeing tour at Leaning Tower Of Pisa and explore the noteworthy features. Next, make your way to Piazza Del Duomo, Pisa, another highlight in Pisa.

At the end of the day, you will drive to Florence, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

Indulge in a memorable dining experience at one of Florence's most popular restaurants, and connect with friendly locals for a true cultural experience.

Set out on a gastronomic journey in Florence by reserving a table at Enoteca Pinchiorri. Renowned for its 3-star Michelin recognition, this restaurant presents an outstanding menu of italian contemporary cuisine. For a different taste, head over to Santa Elisabetta, renowned for its delectable creative and mediterranean dishes. This distinguished 2-star Michelin-recipient is a favorite among guests, making it a worthy addition to your holiday plans. Craving more culinary excitement? Explore Gucci Osteria da Massimo Bottura, a highly rated local gem known for its exquisite italian contemporary and international menu. With a 1-star Michelin acclaim, it promises a dining experience you won't want to miss.

Cap off your dinner by heading to Manifattura, ideal for a leisurely evening with a drink in hand. Se·sto On Arno Rooftop Bar is another bar that offers an enjoyable setting. Similarly, Il Vinile is also a popular place to go on a night out, perfect for relaxing and socializing.

As the sun sets, rest up and recharge for the next leg of your road trip in Italy.

Day 11 offers an itinerary packed with the best things to see in Rome. You’ll stay in Florence for 2 nights more, offering you enough time to explore at a relaxed pace.

Palazzo Vecchio brings Florence's character to life. This history-steeped palace is a highlight of any visit in the city. Then, enjoy Piazza Della Signoria, another history-steeped attraction that never fails to captivate visitors. Next, head over to Ponte Vecchio, one of the city’s most iconic attractions, known for its culturally significant features.

If you’re looking for more, spend time soaking in the atmosphere of Uffizi Gallery. This romantic art gallery is frequented by locals and tourists alike. To complete your memorable day, make sure to visit Piazzale Michelangelo, a top-rated observation deck, and take a stroll around the area.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

After a day of adventure, treat yourself to an exquisite dinner at one of Florence's best restaurants.

Enjoy a lovely meal at Ditta Artigianale, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Trattoria Da Burde is another top choice with a popular menu. You could also check for a table at Casa Toscana. As an establishment that consistently gains high praises from customers, it’s an ideal choice in Florence tonight.

Unwind after your meal by stepping into Bar 50 Rosso. This venue is celebrated for its extensive drink selections and cozy vibes. Alternatively, Bitter Bar offers a dynamic and energetic atmosphere for a glass or two. Don’t overlook Archea Brewery, another top-rated bar in the area.

Head back to your accommodation in Florence and get some rest to prepare for another magical day of your road trip in Italy.

On day 12 of your road trip, you will have an entire day to discover what to see in Florence. You’ll stay in Florence for 1 night.

One of the most popular attractions included on the itinerary is David. Then, take a leisurely stroll to Galleria Dell'accademia and learn what makes this instagrammable art gallery unique.

Throughout the day, make sure to take breaks to appreciate the surroundings. Next up, visit the interesting Central Market. After exploring the food market, head to Brunelleschi's Dome. This underrated monument is a highlight in Florence. As your day continues, stop by Cathedral Of Santa Maria Del Fiore, known for its majestic features.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Florence. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Treat yourself to a delightful dinner at Ristorante Buca Mario, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Agricola Toscana? It's another excellent option with a diverse menu. Consider reserving a table at Eataly Firenze as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Florence.

Keep the evening going at Gosh*, a great choice for enjoying the after-dinner hours with a drink. You could also go to Antico Caffè Del Moro - Art Bar Firenze, which offers a similarly pleasant setting and great drinks. Another option is Quelo Bar, which provides an inviting environment for unwinding after a busy day out.

Relax and recharge in preparation for another adventurous day in Italy!

Your itinerary for day 13 of your road trip in Italy includes 2 stops and features some of the highlights of Florence and Orvieto. At the end of the day, enjoy the comforts of a top-rated hotel in Rome, where you'll spend 1 night.

Make a stop at Pitti Palace. This popular palace is a must-visit for travelers looking for a unique holiday experience. Make your way to Basilica Of Santa Croce In Florence located in Florence for another exciting encounter.

After soaking in Florence’s unique atmosphere, jump into the car with a full heart and drive in the direction of your next destination: Orvieto. Expect your car journey to take a minimum of 1 hour 55 min. When you arrive in Orvieto, it's time to take a break from the road.

Savor the day by heading to Orvieto Cathedral, a notable church that draws visitors from near and far.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Rome. Rome offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Rome, it's often a good idea to reserve a table in advance.

Enjoy a delicious meal at Sofitel Roma Villa Borghese, a highly-rated dining destination in Rome. If you're eager to try something different, consider Centro, another top spot with a tantalizing menu. You might also want to secure a reservation at Ristorante Tema. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Rome this evening.

Take some time to reflect on your day and savor another beautiful night in Italy.