Two-Week Italy Self-Drive Road Trip With Itinerary from Brindisi traveling west to Bari, Naples, Perugia, Florence, Rome, and Salerno

Dive into day 2 of your remarkable road trip in Italy. Today you'll explore 3 destinations, including Ostuni, Fasano, and Egnazia scavi. At the end of the day, you’ll unwind at one of the finest accommodations in Bari, where you'll spend 1 night.

Ostuni’s wonders await as you prepare for another journey on the road, leaving the breathtaking surroundings of Brindisi behind. This drive usually takes around 35 min. Ostuni welcomes you with a multitude of unique vacation experiences.

When you're ready for some sights, head to Parco Naturale Regionale Dune Costiere Da Torre Canne A Torre S.leonardo, a curiosity-inducing nature reserve in Ostuni. Explore its romantic features at your own pace before you continue your journey.

It’s time to gear up for the next part of your road trip adventure. Under favorable conditions, your drive to Fasano may take around 19 min. Upon your arrival in Fasano, you’ll be greeted with the opportunity to do some sightseeing and exploring.

Enjoy sightseeing at your own pace and allow yourself time to explore the beautiful surroundings. Take your self-guided tour to Zoosafari Fasanolandia, an interesting safari park that everyone visiting Fasano should see.

Set your GPS to Egnazia scavi and hit the road. Expect a journey of approximately 15 min without stops. Soak in the beautiful landscapes as you drive and look forward to exploring your next destination. Egnazia scavi beckons with new experiences!

Our first attraction recommendation in Egnazia scavi is Lido Ottagono, an up-and-coming beach that draws attention for its romantic features.

When you’re done exploring for the day, you’ll drive to your hotel in Bari. Check in and relax before you head out to tour the city.

Indulge in a memorable dining experience at one of Bari's most popular restaurants, and connect with friendly locals for a true cultural experience.

Don’t miss out on dining at Fabulà Bari, a top-rated dining destination in Bari. If you're in the mood to try something new, consider AncheCinema, another top spot with a mouthwatering menu. You might also want to secure a reservation at La Tana del Polpo. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Bari this evening.

After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at Noise, a well-loved spot among locals and tourists. Or, head to Luau Tiki Bar. This bar boasts a welcoming environment that is perfect for winding down. You could also continue your night at Mercantilenove, another top-rated place in the area.

Celebrate another amazing day of your road trip adventure in Italy!

On day 3 of your road trip in Italy, your travel plans include 2 stops at the most scenic, wondrous, and interesting places in the region. Pompei and Ercolano are on today's agenda. In the evening, you’ll end up in Naples, where you will stay for 2 nights.

When you’re ready to jump back into the car and say goodbye to Bari, you’ll hit the road in the direction of Pompei. This drive usually takes around 3 hours 1 min.

Amphitheatre Of Pompeii is a well-known archeological site we recommend visiting today. Discover its breathtaking features before continuing your self-guided tour to Archaeological Park Of Pompeii, an UNESCO world heritage-designated archeological site that’s well-regarded in the area.

When you’ve had your share of Pompei, prepare for your next destination. Admire the views and listen to some good music as you drive in the direction of Ercolano. Your travel time is around 35 min.

Spend your afternoon discovering Vesuvio National Park, a well-known national park known for its picturesque features.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Naples. Naples offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Naples, it's often a good idea to reserve a table in advance.

Discover the culinary delights of Naples by securing a reservation at Veritas. Esteemed for its 1-star Guide Michelin recognition, this restaurant offers a remarkable selection of campanian and contemporary cuisine. For an alternative dining experience, try Il Comandante, renowned for its delicious creative and mediterranean dishes. This esteemed 1-star Michelin-recipient consistently impresses guests, making it a must-visit spot during your holiday. Craving more culinary excitement? Head to ARIA, a highly recommended local eatery celebrated for its mouthwatering contemporary and modern menu. With its 1-star Michelin recognition, it offers an unforgettable dining adventure.

Unwind after your meal by stepping into Happening Cocktail Bar. This venue is celebrated for its extensive drink selections and cozy vibes. Alternatively, Shanti Art Musik Bar offers a dynamic and energetic atmosphere for a glass or two. Don’t overlook Gran Caffè Gambrinus, another top-rated bar in the area.

As the sun sets, rest up and recharge for the next leg of your road trip in Italy.

On day 4 of your road trip, you will have an entire day to discover what to see in Naples. You’ll stay in Naples for 1 night.

To truly experience Naples, make sure to drop by Castel Sant'elmo. This interesting castle is a must-visit for anyone seeking a unique vacation experience. Another sight you shouldn’t miss is Naples National Archaeological Museum, one of the city’s best highlights.

Next, check out Cappella Sansevero, one of the most notable places to see in Naples. This museum is a favorite among locals and travelers alike. Enjoy some downtime and refreshments before continuing to your next stop, Ovo Castle. Wander around and soak in the enchanting atmosphere this castle offers.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

Indulge in a memorable dining experience at one of Naples's most popular restaurants, and connect with friendly locals for a true cultural experience.

Treat yourself to a wonderful meal at Antica Pizzeria Di Matteo, a top-rated dining spot in Naples. If you're in the mood for something new, try Mercure Napoli Centro Angioino, another premier location with a delectable menu. You might also want to book a table at La Lazzara Trattoria e Pizzeria. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Naples.

After your delicious meal, get a taste of the vibrant nightlife with a visit to Archivio Storico - Cocktail Bar & Wonderfood, known for its inviting atmosphere. Archeobar is another great option if you’re looking for a place to get the night started. Similarly, Babette Pub provides a great setting to enjoy the night away.

Get a good night's sleep and look forward to another great day on the road in Italy!

On day 6 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, including Pisa. When you’re not sightseeing, take time to relax at your chosen hotel in Florence, where you’ll be staying for 3 nights.

Embrace the thrill of the open road as you wave goodbye to Perugia and set your GPS to Pisa. While on the road, immerse yourself in your favorite road trip tunes or sample the sounds from a local radio station. This car ride usually takes around 2 hours 45 min. Upon reaching Pisa, unwind, observe, and explore. The best things to do, see, and eat are waiting for you.

Our first attraction recommendation in Pisa is Knights' Square, an often recommended public square that draws attention for its historic features. Spend some time soaking in the atmosphere before continuing to Leaning Tower Of Pisa, a breathtaking monument that stands out in the city.

Time flies when you're having fun! But don't forget to stop for a bit to eat and drink between your adventures. When you're rested and recharged, head to Piazza Del Duomo, Pisa, an iconic public square that offers a unique experience. Be sure to also explore Pisa Cathedral, a nearby church, highly recommended by other travelers.

When you’re done exploring for the day, you’ll drive to your hotel in Florence. Check in and relax before you head out to tour the city.

Florence is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Florence.

Prepare for an extraordinary culinary adventure in Florence by booking a table at Enoteca Pinchiorri, a 3-star Michelin restaurant that boasts an exceptional italian contemporary menu. For a different flavor experience, head to Santa Elisabetta, renowned for its delectable creative and mediterranean dishes. This 2-star Michelin restaurant consistently wows guests, making it a memorable stop during your holiday. Looking for another option? Visit Gucci Osteria da Massimo Bottura, a local gem known for its delightful italian contemporary and international cuisine in Florence. Nestled in the city's heart, this 1-star Michelin restaurant is a perfect choice for discerning restaurant-goers seeking a new experience.

Continue your lively evening at Manifattura, a perfect place for winding down or revving up the night, depending on which mood you’re in. Se·sto On Arno Rooftop Bar is another excellent bar that offers a great selection of drinks to suit any mood. If you prefer to go somewhere else, Il Vinile ensures a night out tailored to your taste.

Get a good night's sleep and look forward to another great day on the road in Italy!

Day 7 offers an itinerary packed with the best things to see in Brindisi. You’ll stay in Florence for 2 nights more, offering you enough time to explore at a relaxed pace.

Check out the globally renowned historical landmark, Ponte Vecchio. Afterward, continue to Uffizi Gallery, an art gallery every traveler should visit. As you explore Florence’s charming streets, take in the lively atmosphere and get to know the character of the city.

Next, make your way to Piazza Della Signoria. This famous public square is an essential stop. Following that, head to Basilica Of Santa Croce In Florence, another must-visit site that will enhance your experience. Don’t forget to stop by Piazzale Michelangelo, a widely recognized observation deck in the city.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

Florence is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Florence.

Make sure to reserve a table at Ditta Artigianale, an iconic dining spot in Florence. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Trattoria Da Burde, a popular restaurant in Florence. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Casa Toscana, a hidden gem nestled in Florence. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Continue the enjoyment post-dinner at Bar 50 Rosso, a cherished local gathering spot renowned for its welcoming atmosphere. Similarly, Bitter Bar offers a vibrant space for indulging in well-crafted drinks and engaging conversation. You may also want to check out Archea Brewery. This bar is a favorite among both locals and visitors looking for a delightful evening out filled with laughter and fun.

Take some time to reflect on your day and savor another beautiful night in Italy.

Day 8 of your road trip across Italy promises a magnificent time exploring what to see in Florence. You have 1 night left in Florence. Take the opportunity to experience more of the best attractions and activities in the city.

Basilica Di Santa Maria Novella, Firenze (fi) brings Florence's character to life. This visually striking church is a highlight of any visit in the city. Then, enjoy Central Market, another eye-catching attraction that never fails to captivate visitors. Next, head over to Cathedral Of Santa Maria Del Fiore, one of the city’s most spectacular attractions, known for its inviting features.

If you’re looking for more, spend time soaking in the atmosphere of Galleria Dell'accademia. This detailed art gallery is frequented by locals and tourists alike. To complete your memorable day, make sure to take a stroll around the area.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Florence. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Treat yourself to a delicious dinner at Ristorante Buca Mario, an excellent option for tonight's dining. Looking for something different? Agricola Toscana offers a tantalizing alternative with its diverse menu. And don’t miss Eataly Firenze. Known for great service, it’s a fantastic choice for tonight in Florence.

After savoring a delicious meal, step into the vibrant nightlife at Gosh*, where the evening is just getting started. In the same way, Antico Caffè Del Moro - Art Bar Firenze offers a unique charm perfect for experiencing the local bar scene in Florence. Quelo Bar is another top-recommended bar that is sure to get you into the mood for some dancing and celebrating.

Say good night to Florence and look forward to another great day of your road trip in Italy!

Your itinerary for day 9 of your road trip in Italy includes 1 stop and features some of the highlights of Vatican City. At the end of the day, enjoy the comforts of a top-rated hotel in Rome, where you'll spend 4 nights.

Fasten your seatbelt and make your way to your next stop — Vatican City, home to many well-known sights in the region. Keep in mind that your travel time from Florence to Vatican City may take around 3 hours 14 min without traffic disruptions. Upon arrival in Vatican City, we highly recommend checking out some of the top attractions.

One of our top recommendations for your sightseeing is Sistine Chapel. Then, head to St. Peter's Basilica. This world-famous major basilica is a traveler-favorite in the city.

If you're keen to see more, continue to Saint Peter's Square. Feed your curiosity by learning something new about the square. Next, take your journey to Vatican Museums, a globally renowned art museum.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Rome. Rome offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a day of adventure, treat yourself to an exquisite dinner at one of Rome's best restaurants.

Set out on a gastronomic journey in Rome by reserving a table at La Pergola. Renowned for its 3-star Michelin recognition, this restaurant presents an outstanding menu of mediterranean and contemporary cuisine. For a different taste, head over to Il Pagliaccio, renowned for its delectable creative and innovative dishes. This distinguished 2-star Michelin-recipient is a favorite among guests, making it a worthy addition to your holiday plans. Craving more culinary excitement? Explore Enoteca La Torre, a highly rated local gem known for its exquisite mediterranean and creative menu. With a 2-star Michelin acclaim, it promises a dining experience you won't want to miss.

Keep the excitement of the evening going by visiting a bar or two. La Botticella Of Poggi Giovanni is an excellent place to start. You could also check out Almalu Trastevere, offering a different kind of charm. A last recommendation for the day is Bar Viminale Di Pepi Maurilio. This bar promises an enjoyable experience with tasty drinks and a vibrant setting.

Relax and recharge in preparation for another adventurous day in Italy!

Day 10 of your road trip will take you to the best attractions Rome has to offer. Cherish the 3 nights you have left in the city and use the provided itinerary to discover what to see in Rome.

Make a stop at Piazza Del Popolo. This spectacular public square is a must-visit for travelers looking for a unique holiday experience. Make your way to Villa Borghese located in Rome for another exciting encounter.

Next, immerse yourself in the setting of Basilica Di Santa Maria Maggiore. Its culturally significant features will captivate you. After the church, continue your tour of the city with a visit to Colosseum. Visitors usually appreciate the culturally significant features of this archeological site. Next up is Roman Forum, a highly recommended archeological site.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

After a day of adventure, treat yourself to an exquisite dinner at one of Rome's best restaurants.

Savor the flavors at RomAntica, a top pick for dinner tonight. Alternatively, Coso Ristorante beckons with its unique menu offerings. Also, consider DEROMA - Farine Romane. With its consistent customer satisfaction, it’s an excellent option for dining in Rome tonight.

Continue your evening by exploring the vibrant nightlife scene at Sant' Eustachio Caffè, a prime destination for a thrilling night out. Also, don’t forget to check out Yellowsquare Rome, a bar that offers unique local touches. Likewise, Caffè Portofino provides an excellent alternative for a fun evening.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in Italy.

On day 11 of your road trip, you will have an entire day to discover what to see in Rome. You’ll stay in Rome for 2 nights.

No visit to Rome is complete without Foro Italico. This locally renowned sports complex is one of the top attractions in the city. Proceed to Castel Sant'angelo, another must-visit attraction.

As you wander through the inviting streets of Rome, soak in the lively ambiance and take the opportunity to snap some photos. Next, head to Piazza Navona. This globally renowned public square is a traveler-favorite. Not far away, you’ll find Campo De' Fiori, another key site on your sightseeing itinerary. Fontana Dell'acqua Paola is yet another highly recommended place to visit nearby, offering plenty to discover for curious travelers.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Rome. Enjoy a relaxing evening as you savor delicious local cuisine.

Enjoy a delicious meal at Hotel de Russie, a top-rated dining destination in Rome. If you're in the mood to try something new, consider La Taverna Italiana, another top spot with a mouthwatering menu. You might also want to secure a reservation at The Parrot Bar. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Rome this evening.

Explore the vibrant nightlife at The Apartment Bar Roma after your meal, a hub for lively evenings and memorable moments. Or, head to Hotel Hassler Roma for a great selection of flavorful drinks and a charming setting.

Raise your glass to another unforgettable day in Italy!

Day 12 offers an itinerary packed with the best things to see in Brindisi. You’ll stay in Rome for 1 night more, offering you enough time to explore at a relaxed pace.

Whether you decide to explore Rome on foot, use public transport, or join a guided tour, there are a few attractions you don’t want to miss.

Pantheon is perfect for a self-paced visit during the day. This respected monument is sure to impress. Next on your list is Largo Di Torre Argentina, another must-visit landmark and popular archeological site renowned for its heritage-rich features.

While exploring and sightseeing, take time to savor the culture of Rome by sampling some local delicacies. When you’re ready for more sightseeing, head to Circus Maximus. This breathtaking archeological site is an essential place to visit for anyone looking for the full Rome experience. We also recommend visiting Orange Garden, an interesting park. Nearby, you'll also find Parco Del Lago Dell'eur, ready to add charm to your journey.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Rome, it's often a good idea to reserve a table in advance.

Make sure to reserve a table at Sofitel Roma Villa Borghese, an iconic dining spot in Rome. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Centro, a popular restaurant in Rome. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Ristorante Tema, a hidden gem nestled in Rome. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Savor another day of unforgettable experiences in Italy!

Dive into day 13 of your remarkable road trip in Italy. Today you'll explore 1 destination, including Rome. At the end of the day, you’ll unwind at one of the finest accommodations in Salerno, where you'll spend 1 night.

Altare Della Patria is must-visit monument and a great option for a daytime tour of the area. Continue your journey to Trevi Fountain, a world-famous monument, located just a leisurely stroll away. Next, head to Spanish Steps, an enchanting public square, also available for your discovery today.

Each stop on today’s itinerary promises to leave you with lasting memories and a deeper appreciation for Rome. When you're ready, let your sightseeing route take you to the timeless Piazza Di Spagna. If you’re looking for more, Archbasilica Of St. John Lateran is also a captivating attraction that is worthwhile a visit.

At the end of the day, you will drive to Salerno, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Salerno. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Experience a harmony of flavors at Re Maurì in Salerno by securing a reservation in advance. Known for its 1-star Michelin status, Re Maurì offers a delightful variety of dishes highlighting its delicious creative menu. If you're looking to mix things up, L'Unico Drink & Food Salerno offers an enticing alternative with its varied menu.

Extend your evening after a delightful meal by visiting Hilton Bar E Gastronomia, which offers the perfect atmosphere for a night out. Moreover, The Black Monday Speakeasy Tbm is another popular option for a drink or two. Likewise, Dòmo I' Vinaino Wine Bar - Enogastronomia also provides a great ambiance for reminiscing about the day and raising a toast to your vacation.

Savor another day of unforgettable experiences in Italy!

On day 14 of your road trip in Italy, your travel plans include 2 stops at the most scenic, wondrous, and interesting places in the region. Salerno and Taranto are on today's agenda. In the evening, you’ll end up in Brindisi, where you will stay for 1 night.

Experience Minerva's Garden, a worthwhile botanical garden in the city.

After soaking in Salerno’s unique atmosphere, jump into the car with a full heart and drive in the direction of your next destination: Taranto. Expect your car journey to take a minimum of 3 hours 3 min. When you arrive in Taranto, it's time to take a break from the road.

When you're ready for some sights, head to Cattedrale San Cataldo, an intriguing church in Taranto. Explore its culturally significant features at your own pace before you continue your journey to your next attraction, Piazza Della Vittoria. This up-and-coming public square is a top recommendation in the area.

When you’re done exploring for the day, you’ll drive to your hotel in Brindisi. Check in and relax before you head out to tour the city.

Indulge in a memorable dining experience at one of Brindisi's most popular restaurants, and connect with friendly locals for a true cultural experience.

Enjoy a lovely meal at Betty - Gelateria Cafe Ristorante Pizzeria a Brindisi, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Bento is another top choice with a popular menu. You could also check for a table at Cozza Nera. As an establishment that consistently gains high praises from customers, it’s an ideal choice in Brindisi tonight.

Raise your glass and celebrate another amazing day of your road trip in Italy!