Two-Week Italy Self-Drive Road Trip With Itinerary from Florence to La Spezia, Bologna, Venice, Milan, and Genoa

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Photo of Florence Aerial View of Ponte Vecchio Bridge during Beautiful Sunny Day, Italy.
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Description

Experience the freedom of the open road on an unforgettable 15-day road trip in Italy! Embark on a self-drive tour that caters to every traveler, featuring destinations like Florence, Pisa, Lucca, Corniglia, Manarola, Riomaggiore, La Spezia, Parma, Bologna, Venice, Verona, Milan, Sirmione, Genoa, Rapallo, Santa Margherita Ligure, and Siena.

This perfectly planned road trip itinerary takes you through some of the best places to see in Italy. You will spend 4 nights in Florence, 1 night in La Spezia, 2 nights in Bologna, 2 nights in Venice, 3 nights in Milan, and 2 nights in Genoa. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Florence, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Piazza San Marco and Rialto Bridge are just a couple of the bucket-list attractions that await your discovery.

As you hit the open road and drive through Florence, Pisa, Lucca, Corniglia, Manarola, Riomaggiore, La Spezia, Parma, Bologna, Venice, Verona, Milan, Sirmione, Genoa, Rapallo, Santa Margherita Ligure, and Siena, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.

Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!

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Driver’s age is 30 - 65
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Pick-up: 10:00
Drop-off: 10:00

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Day 1

Day 1

  • Florence - Arrival day
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  • Cathedral of Santa Maria del Fiore
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Welcome to Florence, the perfect starting point for your road trip in Italy! Pick up your rental car and let the adventure begin. You will spend 3 nights discovering what to see in Florence before embarking on the next leg of your journey.

Florence is a beautiful city with plenty to discover. Taking a stroll in the city center is a great alternative. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

When you're ready for some downtime, make your way to your chosen hotel. Check-in typically starts between 2 and 4 PM in Florence. Make yourself at home and unwind before heading out again.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Florence, it's often a good idea to reserve a table in advance.

Raise a toast to the start of your 15-day road trip in Italy!

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Day 2

Day 2

  • Florence
  • More

Drive 6 km, 1 hour 29 min

  • piazzale Michelangelo
  • Basilica of Santa Croce in Florence
  • Uffizi Gallery
  • Ponte Vecchio
  • piazza della Signoria
  • Galleria dell'Accademia
  • More

You have 2 nights left in Florence. Take the opportunity to experience more of the best attractions and activities in the city.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

Florence is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Florence.

Say good night to Florence and look forward to another great day of your road trip in Italy!

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Day 3

Day 3

  • Florence
  • More

Drive 196 km, 3 hours 14 min

  • Piazza del Duomo, Pisa
  • Leaning Tower of Pisa
  • Guinigi Tower
  • San Michele in Foro
  • Walls of Lucca
  • More

On day 3 of your road trip in Italy, you’ll start and end your day in Florence, but spend the day exploring what’s beyond the city. Since you still have 1 night to spend in Florence, there’s no need to rush. Experience Pisa and Lucca to the fullest today with this curated day itinerary.

When you’re done exploring for the day, you’ll return to Florence and your accommodation.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Florence. Enjoy a relaxing evening as you savor delicious local cuisine.

Savor another day of unforgettable experiences in Italy!

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Day 4

Day 4

  • Florence
  • La Spezia
  • More

Drive 207 km, 4 hours 19 min

  • Chiesa Di San Pietro
  • Cinque Terre National Park
  • Manarola Overlook Viewpoint
  • Riomaggiore
  • Church of San Giovanni Battista of Riomaggiore
  • More

Your itinerary for day 4 of your road trip in Italy includes 3 stops and features some of the highlights of Corniglia, Manarola, and Riomaggiore. At the end of the day, enjoy the comforts of a top-rated hotel in La Spezia, where you'll spend 1 night.

At the end of the day, you will drive to La Spezia, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a day of adventure, treat yourself to an exquisite dinner at one of La Spezia's best restaurants.

Raise your glass and celebrate another amazing day of your road trip in Italy!

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Day 5

Day 5

  • La Spezia
  • Bologna
  • More

Drive 220 km, 3 hours 4 min

  • Palazzo Ducale di Parma
  • Palazzo della Pilotta
  • Teatro Regio
  • Baptistery of Parma
  • Parma Cathedral
  • More

On day 5 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, including Parma. When you’re not sightseeing, take time to relax at your chosen hotel in Bologna, where you’ll be staying for 2 nights.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Bologna. Bologna offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

Bologna is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Bologna.

Take some time to reflect on your day and savor another beautiful night in Italy.

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Day 6

Day 6

  • Bologna
  • More

Drive 5 km, 45 min

  • Fountain of Neptune, Bologna
  • Piazza Maggiore
  • Basilica of San Domenico
  • Piazza Santo Stefano
  • Two Towers
  • Pinacoteca Nazionale di Bologna
  • More

Day 6 offers an itinerary packed with the best things to see in Florence. You’ll stay in Bologna for 1 night more, offering you enough time to explore at a relaxed pace.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

Indulge in a memorable dining experience at one of Bologna's most popular restaurants, and connect with friendly locals for a true cultural experience.

Head back to your accommodation in Bologna and get some rest to prepare for another magical day of your road trip in Italy.

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Day 7

Day 7

  • Bologna
  • Venice
  • More

Drive 160 km, 2 hours 32 min

  • Bridge of Sighs
  • Doge's Palace
  • St Mark's Basilica
  • St Mark's Campanile
  • Piazza San Marco
  • Rialto Bridge
  • More

Experience an unparalleled adventure on day 7 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 place, which are Venice. At the end of the day, you will retreat to the hotel of your choice in Venice, where will spend 2 nights.

When you’re done exploring for the day, you’ll drive to your hotel in Venice. Check in and relax before you head out to tour the city.

Indulge in a memorable dining experience at one of Venice's most popular restaurants, and connect with friendly locals for a true cultural experience.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in Italy.

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Day 8

Day 8

  • Venice
  • More

Drive 4 km, 1 hour 5 min

  • Santa Maria della Salute
  • Basilica S.Maria Gloriosa dei Frari
  • Grand Canal
  • Cannaregio
  • More

You’ll stay in Venice for 1 night.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Venice. Enjoy a satisfying meal that will recharge you for tonight's adventures.

As the sun sets, rest up and recharge for the next leg of your road trip in Italy.

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Day 9

Day 9

  • Venice
  • Milan
  • More

Drive 274 km, 4 hours 6 min

  • Giusti Garden
  • Ponte Pietra
  • piazza delle Erbe
  • Castelvecchio Museum
  • Verona Arena
  • More

Dive into day 9 of your remarkable road trip in Italy. Today you'll explore 1 destination, including Verona. At the end of the day, you’ll unwind at one of the finest accommodations in Milan, where you'll spend 3 nights.

At the end of the day, you will drive to Milan, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Milan. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Get a good night's sleep and look forward to another great day on the road in Italy!

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Day 10

Day 10

  • Milan
  • More

Drive 266 km, 4 hours 16 min

  • Beach brema Sirmione
  • Ponte Levatoio di Sirmione
  • Castello di Sirmione
  • Parrocchia di Santa Maria Maggiore
  • Archaeological site of Grotte di Catullo
  • More

On day 10 of your road trip, you’ll start and end your day in Milan, where you have 2 nights left to stay.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Milan.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Milan, it's often a good idea to reserve a table in advance.

Head back to your accommodation in Milan and get some rest to prepare for another magical day of your road trip in Italy.

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Day 11

Day 11

  • Milan
  • More

Drive 7 km, 1 hour 2 min

  • Arch of Peace
  • Sempione Park
  • Castello Sforzesco
  • Pinacoteca di Brera
  • Galleria Vittorio Emanuele II
  • Duomo di Milano
  • More

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Milan. Enjoy a relaxing evening as you savor delicious local cuisine.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in Italy.

Read more
Day 12

Day 12

  • Milan
  • Genoa
  • More

Drive 151 km, 2 hours 44 min

  • Lighthouse of Genoa
  • Galata - Museo del mare
  • Aquarium of Genoa
  • Via Garibaldi
  • piazza De Ferrari
  • More

On day 12 of your road trip in Italy, your travel plans include 1 stop at the most scenic, wondrous, and interesting places in the region. Genoa are on today's agenda. In the evening, you’ll end up in Genoa, where you will stay for 2 nights.

Throughout the day, make sure to take breaks to appreciate the surroundings.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Genoa. Genoa offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Genoa, it's often a good idea to reserve a table in advance.

Say good night to Genoa and look forward to another great day of your road trip in Italy!

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Day 13

Day 13

  • Genoa
  • More

Drive 93 km, 2 hours 43 min

  • Area Marina Protetta di Portofino
  • Golf Rapallo
  • Rapallo Castle
  • Santa Margherita Ligure Castle
  • San Giacomo di Corte (santuario di Nostra Signora della Lettera)
  • More

On day 13 of your road trip, you'll get the chance to experience San Fruttuoso di Camogli, Rapallo, and Santa Margherita Ligure. At the end of the day, you'll drive back to Genoa, where you still have 1 night left to stay.

When you’re done exploring for the day, you’ll return to Genoa and your accommodation.

After a day of adventure, treat yourself to an exquisite dinner at one of Genoa's best restaurants.

Celebrate another amazing day of your road trip adventure in Italy!

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Day 14

Day 14

  • Genoa
  • Florence
  • More

Drive 374 km, 4 hours 53 min

  • Porta Pispini
  • piazza del Campo
  • Battistero di San Giovanni Battista
  • Siena Cathedral
  • More

Your itinerary for day 14 of your road trip in Italy includes 1 stop and features some of the highlights of Siena. At the end of the day, enjoy the comforts of a top-rated hotel in Florence, where you'll spend 1 night.

When you’re done exploring for the day, you’ll drive to your hotel in Florence. Check in and relax before you head out to tour the city.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Florence. Enjoy a relaxing evening as you savor delicious local cuisine.

Head back to your accommodation in Florence and get some rest to prepare for another magical day of your road trip in Italy.

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Day 15

Day 15

  • Florence - Departure day
  • More
  • Strozzi Palace
  • More

Day 15 of your road trip in Italy is your departure day. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!

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How it works

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Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

We guarantee

Your trip is protected, personalized, and priced right. No surprises, no stress.

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