Two-Week Italy Self-Drive Road Trip With Itinerary from Genoa to La Spezia, Florence, Siena, Rome, and Naples

Day 2 of your road trip will take you to the best attractions Genoa has to offer. Cherish the 1 night you have left in the city and use the provided itinerary to discover what to see in Genoa.

Porto Antico is perfect for a self-paced visit during the day. This romantic public square is sure to impress. Next on your list is Aquarium Of Genoa, another must-visit landmark and spectacular aquarium renowned for its stunning features.

While exploring and sightseeing, take time to savor the culture of Genoa by sampling some local delicacies. When you’re ready for more sightseeing, head to Via Garibaldi. This history-steeped street is an essential place to visit for anyone looking for the full Genoa experience. We also recommend visiting Palazzo Podestà, a worthwhile palace. Nearby, you'll also find Lighthouse Of Genoa, ready to add charm to your journey.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Genoa. Enjoy a relaxing evening as you savor delicious local cuisine.

Treat yourself to a wonderful meal at Zeffirino, a top-rated dining spot in Genoa. If you're in the mood for something new, try Trattoria Vegia Zena, another premier location with a delectable menu. You might also want to book a table at Trattoria delle Grazie. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Genoa.

Head back to your accommodation in Genoa and get some rest to prepare for another magical day of your road trip in Italy.

Experience an unparalleled adventure on day 3 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 3 places, which are Corniglia, Manarola, and Riomaggiore. At the end of the day, you will retreat to the hotel of your choice in La Spezia, where will spend 2 nights.

Throughout the day, make sure to take breaks to appreciate the surroundings.

Continue your road trip and head to your next destination, Corniglia. This car ride takes around 1 hour 44 min.

Set out on a self-guided sightseeing tour at Cinque Terre National Park and explore the eye-catching features.

Continue your road trip and head to your next destination, Manarola. This car ride takes around 15 min.

Enjoy sightseeing at your own pace and allow yourself time to explore the beautiful surroundings. Take your self-guided tour to Manarola Overlook Viewpoint, a curiosity-inducing observation deck that everyone visiting Manarola should see.

Once you're ready to continue your road trip, it's time to buckle up and drive, eagerly anticipating your arrival in Riomaggiore. This drive usually takes around 10 min, without any stops or traffic disruptions.

Spend your afternoon discovering Nostra Signora Di Montenero, an intriguing church known for its inviting features.

At the end of the day, you will drive to La Spezia, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in La Spezia. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Treat yourself to a delightful dinner at The Colombaio Park, highly recommended for tonight's dining.

Relax and recharge in preparation for another adventurous day in Italy!

Wake up to day 4 of your road trip in Italy. On this day, you’ll embark on an exciting expedition discovering the enchanting sights and activities of Vernazza and Riomaggiore. With 1 night to stay in La Spezia, we encourage you to seize the day and discover the unexplored beauty of the city’s surroundings!

Fasten your seatbelt and make your way to your next stop — Vernazza, home to many well-known sights in the region. Keep in mind that your travel time from La Spezia to Vernazza may take around 49 min without traffic disruptions. Upon arrival in Vernazza, we highly recommend checking out some of the top attractions.

When you're ready for some sights, head to Church Of St. Margaret Of Antioch, an underrated church in Vernazza. Explore its monumental features at your own pace before you continue your journey to your next attraction, Ruins Of Doria Tower. This frequently visited monument is a top recommendation in the area.

Continue your road trip and head to your next destination, Riomaggiore. This car ride takes around 35 min.

When you're ready for some sights, head to Church Of San Giovanni Battista Of Riomaggiore, an underrated church in Riomaggiore. Explore its monumental features at your own pace before you continue your journey to your next attraction, Castle Of Riomaggiore. This worthwhile castle is a top recommendation in the area.

When you’re ready to explore more, Riomaggiore is an excellent choice.

When you’re done exploring for the day, you’ll return to La Spezia and your accommodation.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in La Spezia. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Head back to your accommodation in La Spezia and get some rest to prepare for another magical day of your road trip in Italy.

On day 5 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, including Florence. When you’re not sightseeing, take time to relax at your chosen hotel in Florence, where you’ll be staying for 2 nights.

Embrace the thrill of the open road as you wave goodbye to La Spezia and set your GPS to Florence. While on the road, immerse yourself in your favorite road trip tunes or sample the sounds from a local radio station. This car ride usually takes around 1 hour 53 min. Upon reaching Florence, unwind, observe, and explore. The best things to do, see, and eat are waiting for you.

Enjoy sightseeing at your own pace and allow yourself time to explore the beautiful surroundings. Take your self-guided tour to Bargello National Museum, a locally appreciated museum that everyone visiting Florence should see. Next, head to Palazzo Vecchio. This awe-inspiring palace is one of the most interesting attractions in the region.

If you're keen to see more, don’t miss out on Uffizi Gallery, a standout art gallery popular among locals as well as travelers. Ponte Vecchio is an excellent attraction to visit next. Spend some time learning more about this iconic historical landmark before you continue your journey. Lastly, visit Piazza Della Signoria, a visually striking public square and a top attraction in the city.

When you’re done exploring for the day, you’ll drive to your hotel in Florence. Check in and relax before you head out to tour the city.

After a day of adventure, treat yourself to an exquisite dinner at one of Florence's best restaurants.

Enjoy a lovely dining experience at Ristorante Oliviero 1962, a popular restaurant in Florence. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Florence at Di Poneta Novoli, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated Caffe San Firenze. It’s yet another ideal choice to enhance your time in Florence tonight.

Let the evening flow smoothly from dinner to drinks at Manifattura, a top-rated bar in the area. For other recommendations, Se·sto On Arno Rooftop Bar provides a perfect setting for rounding out your night with style and great drinks. Likewise, Il Vinile offers a memorable night with diverse drink options and excellent service.

Take some time to reflect on your day and savor another beautiful night in Italy.

Day 6 offers an itinerary packed with the best things to see in Genoa. You’ll stay in Florence for 1 night more, offering you enough time to explore at a relaxed pace.

Awaiting your discovery is the locally appreciated Porta Romana, a photogenic monument in Florence. Next, go to Piazzale Michelangelo.

After visiting Porta Romana and Piazzale Michelangelo, have a stroll along Florence's streets and take in the local charm. Continue your sightseeing by heading to Basilica Of Santa Croce In Florence. This culturally significant church offers a unique experience. Cathedral Of Santa Maria Del Fiore is another noteworthy attraction worthwhile a visit. End your self-guided sightseeing tour on top with a visit to Galleria Dell'accademia, one of the most photogenic places to visit in Florence. If you still have some time left for sightseeing, we also recommend stopping by Central Market.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Florence. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Enjoy a lovely meal at Ditta Artigianale, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Trattoria Da Burde is another top choice with a popular menu. You could also check for a table at Casa Toscana. As an establishment that consistently gains high praises from customers, it’s an ideal choice in Florence tonight.

If you’re not ready to end the night just yet, Bar 50 Rosso offers a perfect venue to relax and savor a drink. Similarly, Bitter Bar is well-suited for those looking to unwind in a social setting. Archea Brewery is another excellent spot to enjoy a nightcap after a delightful meal.

Get a good night's sleep and look forward to another great day on the road in Italy!

Your itinerary for day 7 of your road trip in Italy includes 1 stop and features some of the highlights of Siena. At the end of the day, enjoy the comforts of a top-rated hotel in Siena, where you'll spend 2 nights.

After soaking in Florence’s unique atmosphere, jump into the car with a full heart and drive in the direction of your next destination: Siena. Expect your car journey to take a minimum of 1 hour 8 min. When you arrive in Siena, it's time to take a break from the road.

Basilica Of San Domenico is an often recommended church we recommend visiting today. Discover its historic features before continuing your self-guided tour to Piazza Del Duomo, an UNESCO world heritage-listed public square that’s well-regarded in the area.

Next, stop by Siena Cathedral, a visually striking church. While you’re nearby, don’t forget to visit Pubblico Palace, a culturally significant and truly unique palace. End your sightseeing at Piazza Del Campo, a spectacular public square that’s highly recommended by travelers passing through the city.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Siena. Siena offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Siena. Enjoy a relaxing evening as you savor delicious local cuisine.

Don’t miss out on dining at Enoteca I Terzi, a top-rated dining destination in Siena. If you're in the mood to try something new, consider Ristorante Tar-Tufo, another top spot with a mouthwatering menu. You might also want to secure a reservation at Antica Trattoria Papei. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Siena this evening.

After savoring a delicious meal, step into the vibrant nightlife at Meet Life Cafè, where the evening is just getting started. In the same way, Maudit Pub offers a unique charm perfect for experiencing the local bar scene in Siena. Bar Impero Siena is another top-recommended bar that is sure to get you into the mood for some dancing and celebrating.

Relax and look forward to more memorable moments to come!

On day 9 of your road trip in Italy, your travel plans include 1 stop at the most scenic, wondrous, and interesting places in the region. Rome are on today's agenda. In the evening, you’ll end up in Rome, where you will stay for 3 nights.

Fasten your seatbelt and make your way to your next stop — Rome, home to many well-known sights in the region. Keep in mind that your travel time from Siena to Rome may take around 2 hours 39 min without traffic disruptions. Upon arrival in Rome, we highly recommend checking out some of the top attractions.

Savor the day by heading to Spanish Steps, a famous public square that draws visitors from near and far. When you're done, continue to Colosseum, where you can soak in the UNESCO world heritage-designated surroundings.

Next, explore Roman Forum, yet another world-famous place to see in the area. After the archeological site, make time to go to Capitoline Museums. This breathtaking museum is well worth the visit.

At the end of the day, you will drive to Rome, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

Indulge in a memorable dining experience at one of Rome's most popular restaurants, and connect with friendly locals for a true cultural experience.

Treat yourself to a delicious dinner at La Bottega Roma, an excellent option for tonight's dining. Looking for something different? Pasta In Corso offers a tantalizing alternative with its diverse menu. And don’t miss Trattoria Vecchia Roma. Known for great service, it’s a fantastic choice for tonight in Rome.

Continue the enjoyment post-dinner at La Botticella Of Poggi Giovanni, a cherished local gathering spot renowned for its welcoming atmosphere. Similarly, Almalu Trastevere offers a vibrant space for indulging in well-crafted drinks and engaging conversation. You may also want to check out Bar Viminale Di Pepi Maurilio. This bar is a favorite among both locals and visitors looking for a delightful evening out filled with laughter and fun.

Get a good night's sleep and look forward to another great day on the road in Italy!

On day 10 of your road trip, you’ll start and end your day in Rome, where you have 2 nights left to stay.

Trastevere is a fantastic place you can explore today in Vatican City. This neighborhood is a testament to the city’s character, and it's easy to spend hours just walking around and admiring the surroundings. Soak in the Vatican City-way-of-life and visit all the nearby sights. You should also check out Via del Corso, a street offering more opportunities to enjoy the city’s vibrant atmosphere and landmarks.

Vatican City welcomes you with a multitude of unique vacation experiences.

Next, make your way to Sistine Chapel, another highlight in Vatican City.

Nearby, you will also find Vatican Museums. This globally renowned art museum is a top place to see in the area.

When you’re done exploring for the day, you’ll return to Rome and your accommodation.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Rome. Enjoy a relaxing evening as you savor delicious local cuisine.

Treat yourself to a delicious dinner at RomAntica, an excellent option for tonight's dining. Looking for something different? Coso Ristorante offers a tantalizing alternative with its diverse menu. And don’t miss DEROMA - Farine Romane. Known for great service, it’s a fantastic choice for tonight in Rome.

Keep the excitement of the evening going by visiting a bar or two. Sant' Eustachio Caffè is an excellent place to start. You could also check out Yellowsquare Rome, offering a different kind of charm. A last recommendation for the day is Caffè Portofino. This bar promises an enjoyable experience with tasty drinks and a vibrant setting.

Celebrate another amazing day of your road trip adventure in Italy!

Day 11 of your road trip across Italy promises a magnificent time exploring what to see in Rome. You have 1 night left in Rome. Take the opportunity to experience more of the best attractions and activities in the city.

Look forward to a unique sightseeing adventure at the spectacular Villa Borghese and allow yourself time to explore. Just a short distance away you'll find your next stop, Trevi Fountain, a visually striking monument that draws visitors from far and near.

Continue your journey to Pantheon, one of the city’s most globally renowned spots that you shouldn’t miss. Another great site to visit is the well-known Largo Di Torre Argentina. When you're finished at the archeological site, Campo De' Fiori awaits your visit. This public square is a picture-perfect highlight on today's itinerary. Last up is a public square - the world-famous Piazza Navona.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

After a day of adventure, treat yourself to an exquisite dinner at one of Rome's best restaurants.

Make sure to reserve a table at Hotel de Russie, an iconic dining spot in Rome. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of La Taverna Italiana, a popular restaurant in Rome. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of The Parrot Bar, a hidden gem nestled in Rome. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Following your dinner, dive into the local bar culture at The Apartment Bar Roma. Enjoy this evening's relaxed ambiance with delightful drinks. Alternatively, go to Hotel Hassler Roma, the perfect place for those looking to experience the best of the nightlife.

Celebrate another amazing day of your road trip adventure in Italy!

Dive into day 12 of your remarkable road trip in Italy. Today you'll explore 2 destinations, including Pompei and Naples. At the end of the day, you’ll unwind at one of the finest accommodations in Naples, where you'll spend 2 nights.

Pompei’s wonders await as you prepare for another journey on the road, leaving the breathtaking surroundings of Rome behind. This drive usually takes around 2 hours 35 min. Pompei welcomes you with a multitude of unique vacation experiences.

Spend your afternoon discovering Archaeological Park Of Pompeii, a well-known archeological site known for its breathtaking features.

Once you're ready to continue your road trip, it's time to buckle up and drive, eagerly anticipating your arrival in Naples. This drive usually takes around 33 min, without any stops or traffic disruptions.

When you're ready for some sights, head to Spaccanapoli, an underrated street in Naples. Explore its awe-inspiring features at your own pace before you continue your journey to your next attraction, Naples National Archaeological Museum. This popular museum is a top recommendation in the area.

When you’re done exploring for the day, you’ll drive to your hotel in Naples. Check in and relax before you head out to tour the city.

Naples is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Naples.

Dine in style at L'Oca Nera Irish Pub, a top recommendation for dinner tonight. Or, for a change of pace, Mimì alla Ferrovia boasts a menu that's sure to impress. Also, be sure to check out Spuzzulè Winebar. Known as a local hotspot, it’s a great choice for tonight in Naples.

After your meal, keep the night alive at a bar like Happening Cocktail Bar, known for its lively atmosphere. Shanti Art Musik Bar is another top recommendation that provides the perfect setting with well-crafted drinks and a welcoming ambiance. Similarly, Gran Caffè Gambrinus offers an excellent atmosphere for those looking to amp up the evening.

Raise your glass to another unforgettable day in Italy!

Greet day 13 of your road trip in Italy with a smile and start your day with a hearty breakfast. You have 1 night to stay in Naples, so get ready to make the most of your time in the region. On the agenda for this day, you’ll find only the best things to see and do in Positano, Furore, Amalfi, and Ravello.

Continue your road trip and head to your next destination, Positano. This car ride takes around 1 hour 27 min.

Our first attraction recommendation in Positano is Costiera Amalfitana Positano, an up-and-coming beach that draws attention for its awe-inspiring features.

When you’ve had your share of Positano, prepare for your next destination. Admire the views and listen to some good music as you drive in the direction of Furore. Your travel time is around 26 min.

Enjoy sightseeing at your own pace and allow yourself time to explore the beautiful surroundings. Take your self-guided tour to Fiordo Di Furore, a frequently visited fjord that everyone visiting Furore should see.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Naples.

After a day of adventure, treat yourself to an exquisite dinner at one of Naples's best restaurants.

Don’t miss out on dining at Antica Pizzeria Di Matteo, a top-rated dining destination in Naples. If you're in the mood to try something new, consider Mercure Napoli Centro Angioino, another top spot with a mouthwatering menu. You might also want to secure a reservation at La Lazzara Trattoria e Pizzeria. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Naples this evening.

After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at Archivio Storico - Cocktail Bar & Wonderfood, a well-loved spot among locals and tourists. Or, head to Archeobar. This bar boasts a welcoming environment that is perfect for winding down. You could also continue your night at Babette Pub, another top-rated place in the area.

Relax and recharge in preparation for another adventurous day in Italy!