Two-Week Italy Self-Drive Road Trip With Itinerary from Genoa traveling south to Florence, Viterbo, Naples, Rome, and Siena

On day 2 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, Genoa. When you’re not sightseeing, take time to relax at your selected hotel in Florence, where you’ll be staying for 3 nights.

Genoa is brimming with adventures. Today’s wonderful stops include an art gallery, a street, an aquarium, a public square and much more! Begin your sightseeing adventure at the often recommended Palazzo Bianco and allow yourself time to explore. Just a short distance away you'll find your next stop, Via Garibaldi, a history-steeped street that draws visitors from far and near.

Continue your journey to Aquarium Of Genoa, one of the city’s most impressive spots that you shouldn’t miss. Another great site to visit is the popular Porto Antico.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Florence. Florence offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As dinnertime approaches, it's time to head out for a bite to eat in Florence. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Begin your culinary exploration in Florence by securing a reservation at Enoteca Pinchiorri. This renowned restaurant holds 3 Michelin star and offers an exceptional menu of italian contemporary cuisine. For another dining delight, visit Santa Elisabetta, celebrated for its delectable creative and mediterranean menu. This acclaimed 2-star Michelin-recipient consistently leaves guests satisfied, making it a must-visit during your holiday. Looking for a different experience? Discover Gucci Osteria da Massimo Bottura, a top local spot known for its tantalizing italian contemporary and international menu. With a 1-star Michelin recognition, it guarantees an exceptional dining adventure.

Let the evening flow smoothly from dinner to drinks at Manifattura, a top-rated bar in the area. For other recommendations, Se·sto On Arno Rooftop Bar provides a perfect setting for rounding out your night with style and great drinks. Likewise, Il Vinile offers a memorable night with diverse drink options and excellent service.

As the sun sets on another day of adventure, rest up and recharge for the next leg of your road trip in Italy.

Wake up to day 3 of your extraordinary road trip in Italy. With 2 nights left in Florence, we encourage you to seize the day and discover the unexplored beauty of the city’s surroundings!

Today’s route brings fun adventures, romantic experiences, and breathtaking views. The first attraction of today is Piazza Maggiore. This top-rated public square is an enchanting place to see in Florence. Continue your discovery at Two Towers, a picture-perfect monument with stories to tell.

As you stroll around Florence, take in the distinct atmosphere and learn what makes this city so unique. Maximize your sightseeing with a visit to Piazza Santo Stefano. This frequently visited public square offers an enchanting encounter with Florence. Next, make your way to Basilica Of Santa Croce In Florence to add another highlight to your day. Whether you decide to get entrance tickets for all attractions or you prefer admiring from a distance, amazing experiences await on this day in Florence.

When you’re done exploring for the day, you’ll return to Florence and your accommodation.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Florence. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Enjoy a delicious meal at Ditta Artigianale, a top-rated dining destination in Florence. If you're in the mood to try something new, consider Trattoria Da Burde, another top spot with a mouthwatering menu. You might also want to secure a reservation at Casa Toscana. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Florence this evening.

After enjoying a fulfilling meal, continue your evening at Bar 50 Rosso, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, Bitter Bar offers a welcoming atmosphere for easing into the nightlife. Similarly, Archea Brewery provides an excellent environment for a relaxed and enjoyable evening.

Savor another day of unforgettable experiences in Italy!

Day 4 of your road trip will take you to the best attractions Florence has to offer. Cherish the 1 night you have left in Florence by discovering the best things there are to see and do in the city.

Savor the day by visiting some of the best places to see in Florence, including a palace, a historical landmark, an art gallery, a public square and much more! Start your adventure at Pitti Palace. This notable palace is a must-visit for travelers looking for a unique holiday experience. Make your way to Ponte Vecchio located in Florence for another exciting encounter.

Next, immerse yourself in the setting of Uffizi Gallery. Its picture-perfect features will captivate you. After the art gallery, continue your tour of the city with a visit to Piazza Della Signoria. Visitors usually appreciate the history-steeped features of this public square.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

As dinnertime approaches, it's time to head out for a bite to eat in Florence. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Don’t miss out on dining at Ristorante Buca Mario, a top-rated dining destination in Florence. If you're in the mood to try something new, consider Agricola Toscana, another top spot with a mouthwatering menu. You might also want to secure a reservation at Eataly Firenze. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Florence this evening.

Let the evening flow smoothly from dinner to drinks at Gosh*, a top-rated bar in the area. For other recommendations, Antico Caffè Del Moro - Art Bar Firenze provides a perfect setting for rounding out your night with style and great drinks. Likewise, Quelo Bar offers a memorable night with diverse drink options and excellent service.

Raise your glass to another unforgettable day in Italy!

Experience an unparalleled adventure on day 5 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 vibrant destinations - Florence. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Viterbo. You will spend 1 night here for some well-deserved relaxation.

Bring your curiosity for today’s adventure around Florence. Some of the city’s most loved attractions await! Cathedral Of Santa Maria Del Fiore is the perfect place to start. This church is one of the most famous places to visit in Florence. Next, head to Central Market, an interesting food market, known for its instagrammable features.

In between the sights, don’t hesitate to take small detours to explore local stores and eateries. When you’re ready to continue your adventure, head to Galleria Dell'accademia. This photogenic art gallery is a highly recommended experience. Nearby, you'll also find David and Piazzale Michelangelo. Visit these for an interesting touch to your journey.

At the end of the day, you will drive to Viterbo, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

Indulge in a memorable dining experience at one of Viterbo's most popular restaurants, and connect with friendly locals for an authentic adventure.

Raise your glass and celebrate another amazing day of your road trip in Italy!

On day 6 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Caserta and San Leucio-complex. In the evening, you’ll end up in Naples, where you will stay for 3 nights.

Today’s route brings fun adventures, romantic experiences, and breathtaking views. The first attraction of today is Fontana Margherita. Continue your discovery at Giardini Reali - Parco Reggia Di Caserta, a romantic park with stories to tell.

As you stroll around Viterbo, take in the distinct atmosphere and learn what makes this city so unique. Maximize your sightseeing with a visit to Fountain Of Ceres. Next, make your way to Palace Of Caserta to add another highlight to your day. Whether you decide to get entrance tickets for all attractions or you prefer admiring from a distance, amazing experiences await on this day in Viterbo.

When you’re done exploring for the day, you’ll drive to your hotel in Naples. Check in and spend some time relaxing before you head out to tour the city.

As you explore more of Naples, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Enjoy an outstanding dining experience at Veritas, a 1-star Michelin restaurant offering an exceptional campanian and contemporary menu. Alternatively, if you're in the mood for something different, consider the nearby 1-star Michelin-awardee, Il Comandante, known for its delicious creative and mediterranean cuisine. Another highly-recommended place to eat in Naples is ARIA, a renowned restaurant with a 1-star Guide Michelin recognition and a delicious contemporary and modern menu.

After your delicious meal, get a taste of the vibrant nightlife with a visit to Happening Cocktail Bar, known for its inviting atmosphere. Shanti Art Musik Bar is another great option if you’re looking for a place to get the night started. Similarly, Gran Caffè Gambrinus provides a great setting to enjoy the night away.

Take some time to reflect on your day and savor another beautiful night in Italy.

Day 7 of your road trip across Italy promises a magnificent time exploring Naples. You have 2 nights left in Naples. Take the opportunity to experience more of the best attractions and activities in the city.

Enjoy the perfect balance of relaxation and exploration in Naples today. One of the most well-known attractions included on the itinerary is Ovo Castle. This romantic castle will help you start your sightseeing on top. Then, take a leisurely stroll to Piazza Del Plebiscito and learn what makes this visually striking public square unique.

Throughout the day, make sure to take breaks to appreciate the surroundings. Next up, visit the well-known Castel Nuovo. After exploring the castle, head to Castel Sant'elmo. This captivating castle is a highlight in Naples.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Naples. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Have a fantastic dining experience at Antica Pizzeria Di Matteo, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Mercure Napoli Centro Angioino offers an enticing alternative with its varied menu. Additionally, La Lazzara Trattoria e Pizzeria is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Naples.

Unwind after your meal by stepping into Archivio Storico - Cocktail Bar & Wonderfood. This venue is celebrated for its extensive drink selections and cozy vibes. Alternatively, Archeobar offers a dynamic and energetic atmosphere for a glass or two. Don’t overlook Babette Pub, another top-rated bar in the area.

Take some time to reflect on your day and savor another beautiful night in Italy.

On day 8 of your road trip, you’ll start and end your day in Naples, but spend part of the day exploring places of interest outside the immediate city. On today's itinerary, you'll find attractions in Naples, Amalfi, and Ravello. You still have 1 night left in Naples.

Start your adventure at Naples National Archaeological Museum. This interesting museum is a must-visit for travelers looking for a unique holiday experience. Make your way to Cappella Sansevero located in Naples for another exciting encounter.

Next, immerse yourself in the setting of Amalfi Coast. After the coast, continue your tour of the city with a visit to Villa Rufolo. Visitors usually appreciate the history-steeped features of this historical landmark.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Naples.

As dinnertime approaches, it's time to head out for a bite to eat in Naples. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Enjoy a delicious meal at Opera Restaurant, a highly-rated dining destination in Naples. If you're eager to try something different, consider Trattoria San Ferdinando, another top spot with a tantalizing menu. You might also want to secure a reservation at Anonymous Trattoria Gourmet. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Naples this evening.

Continue your lively evening at Gran Caffè Cimmino, a perfect place for winding down or revving up the night, depending on which mood you’re in. Flanagan's Bar is another excellent bar that offers a great selection of drinks to suit any mood. If you prefer to go somewhere else, Bar Napoli ensures a night out tailored to your taste.

Raise your glass to another unforgettable day in Italy!

Embark on another extraordinary experience on day 9 of your road trip in Italy. Today, you will make 1 stop and experience some of the highlights of Vatican City. At the end of the day, you will enjoy the comforts of a top-rated hotel in Rome, which will be your home away from home for 4 nights.

Start your adventure at Vatican Museums. This wondrous art museum is a place that is appreciated by travelers and locals alike.

Consider stopping for a small bite to eat or a drink at a local eatery to keep your energy going. When you’re ready, continue your discovery with a visit to St. Peter's Basilica. This globally renowned major basilica offers an enriching experience. These sights offer a fulfilling end to a perfect day.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Rome. Rome offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a day of adventure, treat yourself to an exquisite dinner at one of Rome's best restaurants.

Set out on a gastronomic journey in Rome by reserving a table at La Pergola. Renowned for its 3-star Michelin recognition, this restaurant presents an outstanding menu of mediterranean and contemporary cuisine. For a different taste, head over to Il Pagliaccio, renowned for its delectable creative and innovative dishes. This distinguished 2-star Michelin-recipient is a favorite among guests, making it a worthy addition to your holiday plans. Craving more culinary excitement? Explore Enoteca La Torre, a highly rated local gem known for its exquisite mediterranean and creative menu. With a 2-star Michelin acclaim, it promises a dining experience you won't want to miss. With its reputation for pleasing customers, it’s a fantastic choice for tonight in Rome.

After savoring a delicious meal, step into the vibrant nightlife at La Botticella Of Poggi Giovanni, where the evening is just getting started. In the same way, Almalu Trastevere offers a unique charm perfect for experiencing the local bar scene in Rome. Bar Viminale Di Pepi Maurilio is another top-recommended bar that is sure to get you into the mood for some dancing and celebrating.

Say good night to Rome and look forward to another great day of your road trip in Italy!

On day 10 of your road trip, you will have an entire day to explore Rome. You’ll stay in Rome for 3 nights and discover all the best things to see and do in the area.

Today’s agenda in Rome includes a castle, a public square, and a monument. Castel Sant'angelo is must-visit castle and a great starting point for the day. Next, continue your journey to Piazza Navona, a timeless public square, located just a leisurely stroll away. Next, head to Pantheon, a culturally significant monument, also available for your discovery today.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Rome. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Savor the flavors at RomAntica, a top pick for dinner tonight. Alternatively, Coso Ristorante beckons with its unique menu offerings. Also, consider DEROMA - Farine Romane. With its consistent customer satisfaction, it’s an excellent option for dining in Rome tonight.

Round off your dining experience by visiting Sant' Eustachio Caffè, a prime location for a drink. Alternatively, explore the distinctive characteristics of Yellowsquare Rome, a bar catering to every mood and preference. Caffè Portofino likewise offers a unique atmosphere, perfect for a memorable night out.

Raise your glass and celebrate another amazing day of your road trip in Italy!

Day 11 offers a multitude of experiences. You will stay in Rome for 2 nights more, offering you enough time to explore at a relaxed pace.

Set out on a day brimming with fun adventures, scenic views, and picturesque spots. Start at the interesting Altare Della Patria, a respected monument in Rome. Next, go to Roman Forum.

After visiting Altare Della Patria and Roman Forum, have a stroll along Rome's streets and take in the local charm. Continue your sightseeing by heading to Colosseum. This UNESCO world heritage-listed archeological site offers a unique experience. Archbasilica Of St. John Lateran is another noteworthy attraction worthwhile a visit.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

After a day of adventure, treat yourself to an exquisite dinner at one of Rome's best restaurants.

Dine in style at Hotel de Russie, a top recommendation for dinner tonight. Or, for a change of pace, La Taverna Italiana boasts a menu that's sure to impress. Also, be sure to check out The Parrot Bar. Known as a local hotspot, it’s a great choice for tonight in Rome.

Following your dinner, dive into the local bar culture at The Apartment Bar Roma. Enjoy this evening's relaxed ambiance with delightful drinks. Alternatively, go to Hotel Hassler Roma, the perfect place for those looking to experience the best of the nightlife.

Celebrate another amazing day of your road trip adventure in Italy!

Day 12 of your road trip will take you to the best attractions Rome has to offer. Cherish the 1 night you have left in Rome by discovering the best things there are to see and do in the city.

Brace yourself for today’s incredible lineup of attractions in Rome, featuring family-friendly attractions, photo-friendly spots, and history-rich sites. Start at Basilica Di Santa Maria Maggiore, a notable church in the city. Then, head to Piazza Del Popolo and soak in the ambiance of this visually striking public square.

There are many interesting places to see in Rome, and when you are ready for more, go to Trevi Fountain. This is one of the city’s most world-famous romantic spots of interest. After exploring the monument, visit the locally renowned Largo Di Torre Argentina.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

Indulge in a memorable dining experience at one of Rome's most popular restaurants, and connect with friendly locals for an authentic adventure.

Make sure to reserve a table at Sofitel Roma Villa Borghese, an iconic dining spot in Rome. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Centro, a popular restaurant in Rome. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Ristorante Tema, a hidden gem nestled in Rome. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Head back to your accommodation in Rome and get some rest in preparation for another magical day of your road trip in Italy!

Dive into day 13 of your remarkable road trip in Italy. Today you will explore Rome, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Siena. You’ll stay here for 1 night.

Whether you prefer a leisurely exploration or a more fast-paced adventure, this itinerary in Rome allows for both. Start by heading to Circus Maximus. This notable archeological site provides an insightful glimpse into the city's identity. Next, discover Piazza Di Spagna, an enchanting public square, promising a delightful encounter.

Continue your sightseeing with a visit to Spanish Steps, a top-rated public square. When you’re done, don’t forget to make a stop at the famous Villa Borghese.

At the end of the day, you will drive to Siena, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Siena. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Enjoy a delicious meal at Enoteca I Terzi, a top-rated dining destination in Siena. If you're in the mood to try something new, consider Ristorante Tar-Tufo, another top spot with a mouthwatering menu. You might also want to secure a reservation at Antica Trattoria Papei. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Siena this evening.

Following your dinner, dive into the local bar culture at Meet Life Cafè. Enjoy this evening's relaxed ambiance with delightful drinks. Alternatively, go to Maudit Pub, the perfect place for those looking to experience the best of the nightlife. Similarly, Bar Impero Siena provides excellent drinks and a great atmosphere, ensuring a memorable night out.

Celebrate another amazing day of your road trip adventure in Italy!

On day 14 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 2 destinations, Siena and Pisa. When you’re not sightseeing, take time to relax at your selected hotel in Genoa, where you’ll be staying for 1 night.

Set out on a day brimming with family-friendly attractions, romantic experiences, and scenic views. Start at the impressive Piazza Del Campo, a visually striking public square in Siena. Next, go to Opera Delle Metropolitana.

After visiting Piazza Del Campo and Opera Delle Metropolitana, have a stroll along Siena's streets and take in the local charm. Continue your sightseeing by heading to Siena Cathedral. This culturally significant church offers a unique experience. Cittadella Nuova is another noteworthy attraction worthwhile a visit.

When you’re done exploring for the day, you’ll drive to your hotel in Genoa. Check in and spend some time relaxing before you head out to tour the city.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Genoa. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Start your culinary exploration in Genoa by securing a reservation at San Giorgio. This renowned restaurant holds 1 Michelin star and offers an exceptional menu of modern and ligurian cuisine. For another dining delight, visit The Cook, celebrated for its delectable modern menu. This acclaimed 1-star Michelin-recipient consistently leaves guests satisfied, making it a must-visit during your holiday. Looking for a different experience? Discover Il Marin, a top local spot known for its tantalizing seafood and contemporary menu. With a 1-star Michelin recognition, it guarantees an exceptional dining adventure.

Relax and recharge in preparation for another adventurous day in Italy!