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Road trips in Italy

3-Day Italy Self-Drive Road Trip With Itinerary Starting in Brindisi

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Ostuni white town skyline at sunset, Brindisi, Apulia southern Italy. Europe.

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Explore the best of Italy on a remarkable 3-day road trip! Combine exploration with relaxation on a self-drive tour featuring Brindisi, Matera, and Alberobello.

This perfectly planned road trip itinerary takes you through some of the best places to see in Italy. You will spend 2 nights in Brindisi. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Brindisi, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Sassi Di Matera and Trulli Di Alberobello Puglia are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Palombaro Lungo, learn more about the unique Belvedere Di Piazza Giovanni Pascoli, and immerse yourself in the vibrant atmosphere of Amici Dei Musei Brindisi.

As you hit the open road and drive through Brindisi, Matera, and Alberobello, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.

Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!

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Driver’s age is 30 - 65

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Day 1

Brindisi - Arrival day
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Lungomare Regina Margherita
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Welcome to Brindisi, the perfect starting point for your road trip in Italy! Pick up your rental car and let the adventure begin. You will spend 2 nights discovering what to see in Brindisi before embarking on the next leg of your journey.

Brindisi is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Amici Dei Musei Brindisi, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Find your way to your hotel in Brindisi. We recommend choosing a hotel in a central location for easy exploring. Check-in typically starts between 2 and 4 PM at hotels in Italy. Settle in and make plans for the evening.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Brindisi, it's often a good idea to reserve a table in advance.

Dine in style at Bracerie Escosazio, a top recommendation for dinner tonight. Or, for a change of pace, Penny boasts a menu that's sure to impress. Also, be sure to check out Piadineria. Known as a local hotspot, it’s a great choice for tonight in Brindisi.

Unwind after your meal by stepping into Peddy Bar. Pasticceria. Gelateria. Happyhour. Prodotti Celiaci. Slot Machines. Scommesse. This venue is celebrated for its extensive drink selections and cozy vibes. Alternatively, Eden Cafè offers a dynamic and energetic atmosphere for a glass or two. Don’t overlook Altair Cafè, another top-rated bar in the area.

Raise a toast to the start of your 3-day road trip in Italy!

Day 2

Brindisi
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Drive 304 km, 4 hours 32 min

Palombaro lungo
Sassi di Matera
Belvedere di Piazza Giovanni Pascoli
Trulli di Alberobello Puglia
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On day 2 of your road trip, you’ll start and end your day in Brindisi, where you still have 1 night left. You'll spend part of the day exploring places of interest outside the immediate city, including Matera and Alberobello.

Matera is brimming with adventures.

Let Palombaro Lungo set the tone for the day. Spend some time admiring this heritage-rich cave system before continuing your journey. Sassi Di Matera is your next stop. This popular archeological site is one of the best-rated sights in Brindisi.

Consider grabbing some lunch or a light snack to keep your energy going. Beyond the above-mentioned attractions, today is also the perfect time to visit Belvedere Di Piazza Giovanni Pascoli. This romantic observation deck is a sight to behold. To round off your sightseeing experience, visit Trulli Di Alberobello Puglia.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Brindisi.

Brindisi is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Brindisi.

Enjoy a lovely dining experience at Betty - Gelateria Cafe Ristorante Pizzeria a Brindisi, a popular restaurant in Brindisi. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Brindisi at Bento, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated Cozza Nera. It’s yet another ideal choice to enhance your time in Brindisi tonight.

Celebrate another amazing day of your road trip adventure in Italy!

Day 3

Brindisi - Departure day
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Palazzo Granafei Nervegna (Brindisi)
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Day 3 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Brindisi before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, begin at Palazzo Granafei Nervegna (brindisi). This underrated palace is a hotspot among locals.

Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Brindisi.

Have a fantastic dining experience at Rendez-Vous Cafè Bistrot, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Pizzeria La Nassa offers an enticing alternative with its varied menu.

You’ll then say farewell to Brindisi. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!

How it works

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Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.

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Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.

Personalize your itinerary

Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.

Easily make changes

Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.

Enjoy seamless planning

With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.

Explore with confidence

From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

Secure your spot

Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.

Get instant confirmation

Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.

Personalize your itinerary

Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.

Easily make changes

Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.

Enjoy seamless planning

With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.

Explore with confidence

From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

We guarantee

Your trip is protected, personalized, and priced right. No surprises, no stress.

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