4-Day Sicily Self-Drive Road Trip With Itinerary from Catania traveling north to Palermo

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Photo of aerial view of Mount Etna, City, beaches and Port, Catania, Sicily, Italy.
Piazza del Duomo in Catania on a summer day, with Duomo of Saint Agatha and the Elephant Fountain. Sicily, southern Italy. View of Cathedral Sant Agata on Piazza del Duomo in Catania, Sicily, Italy.
4-Day Sicily Self-Drive Road Trip With Itinerary from Catania traveling north to Palermo
4-Day Sicily Self-Drive Road Trip With Itinerary from Catania traveling north to Palermo
4-Day Sicily Self-Drive Road Trip With Itinerary from Catania traveling north to Palermo
4-Day Sicily Self-Drive Road Trip With Itinerary from Catania traveling north to Palermo
4-Day Sicily Self-Drive Road Trip With Itinerary from Catania traveling north to Palermo
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Explore the best of Sicily on a remarkable 4-day road trip! Combine exploration with relaxation on a self-drive tour featuring Catania, Palermo, Cefalù, and Taormina.

This perfectly planned road trip itinerary takes you through some of the best places to see in Sicily. You will spend 2 nights in Catania and 1 night in Palermo. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Sicily. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Catania, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Sicily on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Sicily. Ancient Theatre Of Taormina and Giardino Bellini are just a couple of the bucket-list attractions that await your discovery.

As you hit the open road and drive through Catania, Palermo, Cefalù, and Taormina, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Sicily. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Sicily.

Throughout your road trip in Sicily, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Sicily.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Sicily fill up quickly, so book your spot early. Select a date and start planning your road trip in Sicily today!

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Driver’s age is 30 - 65
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Pick-up: 10:00
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Day1

Day 1

  • Catania - Arrival day
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  • Villa Bellini/Chiosco Bellini
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Your road trip adventure in Sicily begins as soon as you reach Catania and pick up your car. You’ll stay here for 1 night and explore what to see in Catania, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.

Catania is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Giardino Bellini. Taking a stroll in the city center is a great alternative. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Find your way to your hotel in Catania. We recommend choosing a hotel in a central location for easy exploring. Check-in typically starts between 2 and 4 PM at hotels in Italy. Settle in and make plans for the evening.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Catania, it's often a good idea to reserve a table in advance.

Make sure to reserve a table at Ristorante da Antonio, an iconic dining spot in Catania. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Lido Arcobaleno, a popular restaurant in Catania. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Lido Azzurro, a hidden gem nestled in Catania. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Explore the vibrant nightlife at Caffè Europa after your meal, a hub for lively evenings and memorable moments. Or, head to Insigne Cafè for a great selection of flavorful drinks and a charming setting. Furthermore, Bohéme Mixology Bar is perfect for those looking to extend their night with a touch of local flavor.

Raise a toast to the start of your 4-day road trip in Sicily!

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Day2

Day 2

  • Catania
  • Palermo
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Drive 212 km, 2 hours 37 min

  • Basilica Cattedrale di Sant'Agata
  • Piazza Università
  • Fountain of the Elephant
  • Greek - Roman theatre
  • Castello Ursino
  • More

Experience an unparalleled adventure on day 2 of your road trip in Sicily. This exciting part of your journey invites you to discover the renowned landmarks in 1 place, which are Catania. At the end of the day, you will retreat to the hotel of your choice in Palermo, where will spend 1 night.

Enjoy all that Catania Cathedral has to offer. This is an up-and-coming church you should not miss. Another must-see is Piazza Università, an often recommended public square in Catania.

When you’re ready for the next sight, head to Elephant Fountain. From there, take a leisurely stroll to Roman Theatre Of Catania, another of the city’s intriguing attractions. We recommend continuing your self-guided tour at Castello Ursino, a photogenic place of interest in the city.

When you’re done exploring for the day, you’ll drive to your hotel in Palermo. Check in and relax before you head out to tour the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Palermo, it's often a good idea to reserve a table in advance.

Treat yourself to an extraordinary dining experience at Buatta Cucina Popolana, a Bib Gourmand restaurant offering an incredible sicilian menu. Alternatively, if your taste buds call for something different, Mec Restaurant is one of the best restaurants for sicilian and contemporary cuisine in Palermo. This 1-star Michelin-awardee earns consistently high praises from guests. We also recommend checking out the menu at Gagini Restaurant. As a top-rated establishment with 1 Michelin star, it is an ideal choice for creative and contemporary cuisine in the city.

Continue your lively evening at Malox Cult, a perfect place for winding down or revving up the night, depending on which mood you’re in. Ai Giudici is another excellent bar that offers a great selection of drinks to suit any mood. If you prefer to go somewhere else, Bar Italico ensures a night out tailored to your taste.

As the sun sets, rest up and recharge for the next leg of your road trip in Sicily.

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Day3

Day 3

  • Palermo
  • Cefalù
  • Taormina
  • Catania
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Drive 336 km, 4 hours 42 min

  • Cathedral of Cefalù
  • Ancient theatre of Taormina
  • Villa Comunale di Taormina
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Your itinerary for day 3 of your road trip in Sicily includes 3 stops and features some of the highlights of Cefalù, Mazzarò, and Taormina. At the end of the day, enjoy the comforts of a top-rated hotel in Catania, where you'll spend 1 night.

When you’ve had your share of Palermo, prepare for your next destination. Admire the views and listen to some good music as you drive in the direction of Cefalù. Your travel time is around 1 hour 1 min.

For a more meaningful self-guided tour of the town's best attractions, visit Cefalù Cathedral, a well-known church that is sure to impress. Take in the surroundings and enjoy the freedom of exploring at your own pace before you continue your journey.

Fasten your seatbelt and make your way to your next stop — Mazzarò, home to many well-known sights in the region. Keep in mind that your travel time from Cefalù to Mazzarò may take around 2 hours 37 min without traffic disruptions. Upon arrival in Mazzarò, we highly recommend checking out some of the top attractions.

Our first attraction recommendation in Mazzarò is Ancient Theatre Of Taormina, a well-known archeological site that draws attention for its romantic features.

Once you're ready to continue your road trip, it's time to buckle up and drive, eagerly anticipating your arrival in Catania. This drive usually takes around 55 min, without any stops or traffic disruptions.

For a more meaningful self-guided tour of the town's best attractions, visit Villa Comunale Di Taormina, a locally appreciated park that is sure to impress. Take in the surroundings and enjoy the freedom of exploring at your own pace before you continue your journey.

At the end of the day, you will drive to Catania, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

Catania is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Catania.

Begin your culinary exploration in Catania by securing a reservation at Me Cumpari Turiddu. This renowned restaurant holds a Bib Gourmand award and offers an exceptional menu of sicilian cuisine. For another dining delight, visit Sapio, celebrated for its delectable sicilian and modern menu. This acclaimed 1-star Michelin-recipient consistently leaves guests satisfied, making it a must-visit during your holiday. Looking for a different experience? Discover Osteria Acqualavica, a top local spot known for its tantalizing sicilian and seafood menu. With a Bib Gourmand recognition, it guarantees an exceptional dining adventure.

Keep the evening going at Circus Cocktail Bar, a great choice for enjoying the after-dinner hours with a drink. You could also go to Caffè Opera, which offers a similarly pleasant setting and great drinks. Another option is Chiosco Sicilia Seltz, which provides an inviting environment for unwinding after a busy day out.

Raise your glass to another unforgettable day in Sicily!

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Day4

Day 4

  • Catania - Departure day
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  • Porta Garibaldi
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Day 4 of your road trip in Sicily is your departure day. This is your chance to catch a last glimpse of Catania before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, we recommend visiting Porta Garibaldi, a history-steeped monument before you head out.

For a shopping spree in Catania, we recommend the lively Via Etnea. Here, you'll find a range of shops you can browse for some souvenir shopping. Discover boutiques with stylish fashion choices to upgrade your wardrobe.

Before you conclude your road trip in Sicily, drop by another restaurant for a last chance at a memorable dining experience in Catania.

You’ll then say farewell to Catania. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Sicily!

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Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

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Your trip is protected, personalized, and priced right. No surprises, no stress.

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