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4-Day Sicily Self-Drive Road Trip With Itinerary from Catania traveling west to Agrigento

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Piazza del Duomo in Catania on a summer day, with Duomo of Saint Agatha and the Elephant Fountain. Sicily, southern Italy. View of Cathedral Sant Agata on Piazza del Duomo in Catania, Sicily, Italy.

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Experience the freedom of the open road on an unforgettable 4-day road trip in Sicily! Embark on a self-drive tour that caters to every traveler, featuring destinations like Catania, Agrigento, and Piazza Armerina.

This perfectly planned road trip itinerary takes you through some of the best places to see in Sicily. You will spend 2 nights in Catania and 1 night in Agrigento. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Sicily. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Catania, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Sicily on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Sicily. Valle Dei Templi and Giardino Bellini are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Villa Romana Del Casale, learn more about the unique Castello Ursino, and immerse yourself in the vibrant atmosphere of Scala Dei Turchi.

As you hit the open road and drive through Catania, Agrigento, and Piazza Armerina, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Sicily. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Sicily.

Throughout your road trip in Sicily, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Sicily.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Sicily fill up quickly, so book your spot early. Select a date and start planning your road trip in Sicily today!

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Day 1

Catania - Arrival day
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Villa Bellini/Chiosco Bellini
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Say hello to Catania! Your exciting road trip through Italy is just about to start. Navigating the top places to see in the region is a breeze with a car. The rental vehicle of your choice will be ready for pickup upon your arrival in the city. You will stay in Catania for 1 night before you continue your adventure!

Catania is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Giardino Bellini, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Find your way to your hotel in Catania. We recommend choosing a hotel in a central location for easy exploring. Check-in typically starts between 2 and 4 PM at hotels in Italy. Settle in and make plans for the evening.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Catania, it's often a good idea to reserve a table in advance.

Have a fantastic dining experience at Ristorante da Antonio, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Lido Arcobaleno offers an enticing alternative with its varied menu. Additionally, Lido Azzurro is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Catania.

Explore the vibrant nightlife at Caffè Europa after your meal, a hub for lively evenings and memorable moments. Or, head to Insigne Cafè for a great selection of flavorful drinks and a charming setting. Furthermore, Bohéme Mixology Bar is perfect for those looking to extend their night with a touch of local flavor.

Raise a toast to the start of your 4-day road trip in Sicily!

Day 2

Catania
Agrigento
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Drive 161 km, 2 hours 15 min

Basilica Cattedrale di Sant'Agata
Piazza Università
Fountain of the Elephant
Greek - Roman theatre
Castello Ursino
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Your itinerary for day 2 of your road trip in Sicily includes 1 stop and features some of the highlights of Catania. At the end of the day, enjoy the comforts of a top-rated hotel in Agrigento, where you'll spend 1 night.

Start your day at Catania Cathedral. This inviting church is a worthwhile place to see in Catania. Then, wander over to Piazza Università. If awe-inspiring sites excite you, this public square will be right up your alley. Nearby, you’ll also find Elephant Fountain. This heritage-rich monument is a favorite among visitors.

Catania offers plenty to explore, ensuring every moment of your visit is filled with excitement and discovery. If you're up for more, Roman Theatre Of Catania is a curiosity-inducing spot in the city that will captivate you with its unique charm. When you’re done at the archeological site, don’t forget to check out the photogenic Castello Ursino. Take a moment to appreciate the fascinating details of this well-known castle.

At the end of the day, you will drive to Agrigento, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

Indulge in a memorable dining experience at one of Agrigento's most popular restaurants, and connect with friendly locals for a true cultural experience.

Treat yourself to a delightful dinner at Ambasciata di Sicilia, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Le Cuspidi? It's another excellent option with a diverse menu. Consider reserving a table at Yellove RistoVintage as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Agrigento.

Celebrate another amazing day of your road trip adventure in Sicily!

Day 3

Agrigento
Catania
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Drive 231 km, 3 hours 45 min

Valle dei Templi
Scala dei Turchi
Temple of Heracles
Villa Romana del Casale
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On day 3 of your exciting self-drive vacation in Sicily, you’ll soak in the magnificence of 3 destinations, including Agrigento, Scavuzzo, and Piazza Armerina. When you’re not sightseeing, take time to relax at your chosen hotel in Catania, where you’ll be staying for 1 night.

Valle Dei Templi is an ideal stop early in the day. This well-known archeological site is a must-visit in the city. When you’re ready for your next discovery, continue to Scala Dei Turchi, which may be one of the most serene places you will experience today.

One of the best things about exploring Agrigento on a self-guided tour is that you set the pace. There’s plenty of time for detours and discovering hidden gems. When you’re ready for your next stop, make your way to Temple Of Heracles, a curiosity-inducing archeological site in the city. If you’re up for more discoveries, don’t forget to reserve some time for Villa Romana Del Casale.

When you’re done exploring for the day, you’ll drive to your hotel in Catania. Check in and relax before you head out to tour the city.

After a day of adventure, treat yourself to an exquisite dinner at one of Catania's best restaurants.

Begin your culinary exploration in Catania by securing a reservation at Me Cumpari Turiddu. This renowned restaurant holds a Bib Gourmand award and offers an exceptional menu of sicilian cuisine. For another dining delight, visit Sapio, celebrated for its delectable sicilian and modern menu. This acclaimed 1-star Michelin-recipient consistently leaves guests satisfied, making it a must-visit during your holiday. Looking for a different experience? Discover Osteria Acqualavica, a top local spot known for its tantalizing sicilian and seafood menu. With a Bib Gourmand recognition, it guarantees an exceptional dining adventure.

After enjoying a fulfilling meal, continue your evening at Circus Cocktail Bar, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, Caffè Opera offers a welcoming atmosphere for easing into the nightlife. Similarly, Chiosco Sicilia Seltz provides an excellent environment for a relaxed and enjoyable evening.

Get a good night's sleep and look forward to another great day on the road in Sicily!

Day 4

Catania - Departure day
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Porta Garibaldi
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Day 4 of your road trip in Sicily is your departure day. This is your chance to catch a last glimpse of Catania before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, we recommend visiting Porta Garibaldi, a history-steeped monument before you head out.

Make the most of your final day in Sicily by visiting Catania’s iconic markets and shopping establishments in the buzzing Centro Commerciale Porte di Catania. Secure the perfect souvenirs for your family and friends back home or buy yourself a remembrance of your amazing vacation.

Before you conclude your road trip in Sicily, drop by another restaurant for a last chance at a memorable dining experience in Catania.

If you're in the mood to try something new, consider Carlito's, another top spot with a mouthwatering menu.

You’ll then say farewell to Catania. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Sicily!

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Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.

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Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.

Easily make changes

Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.

Enjoy seamless planning

With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.

Explore with confidence

From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

Secure your spot

Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.

Get instant confirmation

Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.

Personalize your itinerary

Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.

Easily make changes

Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.

Enjoy seamless planning

With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.

Explore with confidence

From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

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Your trip is protected, personalized, and priced right. No surprises, no stress.

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