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4-Day Sicily Self-Drive Road Trip With Itinerary from Palermo traveling west to Trapani

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Photo of Palermo City, Sicily island in Italy. Aerial view of beautiful Mediterranean town. Drone Photography.

Photo of Palermo, Sicily, Italy. Seafront view.

4-Day Sicily Self-Drive Road Trip With Itinerary from Palermo traveling west to Trapani

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Explore the best of Sicily on a remarkable 4-day road trip! Combine exploration with relaxation on a self-drive tour featuring Palermo, Monreale, Salemi, Nubia, Trapani, Casa Santa, and Agrigento.

This perfectly planned road trip itinerary takes you through some of the best places to see in Sicily. You will spend 2 nights in Palermo and 1 night in Trapani. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Sicily. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Palermo, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Sicily on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Sicily. Valle Dei Templi and Palermo Cathedral are just a couple of the bucket-list attractions that await your discovery.

As you hit the open road and drive through Palermo, Monreale, Salemi, Nubia, Trapani, Casa Santa, and Agrigento, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Sicily. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Sicily.

Throughout your road trip in Sicily, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Sicily.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Sicily fill up quickly, so book your spot early. Select a date and start planning your road trip in Sicily today!

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Driver’s age is 30 - 65

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Day1

Day 1

Palermo - Arrival day
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Foro Italico
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Say hello to Palermo! Your exciting road trip through Italy is just about to start. Navigating the top places to see in the region is a breeze with a car. The rental vehicle of your choice will be ready for pickup upon your arrival in the city. You will stay in Palermo for 1 night before you continue your adventure!

Palermo is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Foro Italico. Taking a stroll in the city center is a great alternative. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

As afternoon approaches, head to your chosen hotel in Palermo. Check-in typically starts around 2 to 4 PM at hotels in Italy. We recommend staying at a central location for easy access to key areas in the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Palermo, it's often a good idea to reserve a table in advance.

Have a fantastic dining experience at Cotto e Bollito, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Bebop offers an enticing alternative with its varied menu. Additionally, Eremiti Restaurant is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Palermo.

Cap off your dinner by heading to Malox Cult, ideal for a leisurely evening with a drink in hand. Ai Giudici is another bar that offers an enjoyable setting. Similarly, Bar Italico is also a popular place to go on a night out, perfect for relaxing and socializing.

Raise a toast to the start of your 4-day road trip in Sicily!

Day2

Day 2

Palermo
Monreale
Salemi
Trapani
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Drive 151 km, 3 hours 10 min

Palermo Cathedral
Quattro Canti
Cattedrale di Monreale
Chiostro Benedettino
Salemi Castle
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Dive into day 2 of your remarkable road trip in Sicily. Today you'll explore 4 destinations, including Palermo, Monreale, Salemi, and Nubia. At the end of the day, you’ll unwind at one of the finest accommodations in Trapani, where you'll spend 1 night.

Your adventure in Palermo is only getting started when you visit Palermo Cathedral, a well-known local hot spot. Another notable attraction to explore is Quattro Canti. This locally renowned public square is known for its breathtaking appeal.

Monreale’s wonders await as you prepare for another journey on the road, leaving the breathtaking surroundings of Palermo behind. This drive usually takes around 24 min. Monreale welcomes you with a multitude of unique vacation experiences.

One of our top recommendations for your sightseeing is Cattedrale Di Monreale. Spend some time admiring the majestic features of the church before you continue to your next stop. Then, head to Chiostro Dei Benedettini. This frequently visited monastery is a traveler-favorite in the city.

When you’re ready to jump back into the car and say goodbye to Monreale, you’ll hit the road in the direction of Salemi. This drive usually takes around 1 hour 13 min.

Enjoy sightseeing at your own pace and allow yourself time to explore the beautiful surroundings. Take your self-guided tour to Salemi Castle, an increasingly popular castle that everyone visiting Salemi should see.

At the end of the day, you will drive to Trapani, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Trapani, it's often a good idea to reserve a table in advance.

Don’t miss out on dining at La Tavernetta, a top-rated dining destination in Trapani. If you're in the mood to try something new, consider Poseidone - Frutti d'amare - Sushi Gourmet, another top spot with a mouthwatering menu. You might also want to secure a reservation at Vintage Restaurant. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Trapani this evening.

Cap off your dinner by heading to Becool Di Catania Pietro. Bar. Pasticceria. Gelateria, ideal for a leisurely evening with a drink in hand.

Raise your glass to another unforgettable day in Sicily!

Day3

Day 3

Trapani
Casa Santa
Agrigento
Palermo
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Drive 356 km, 5 hours 20 min

Tower of King Federico (Bell Tower of the Mother Church)
Valle dei Templi
Scala dei Turchi
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On day 3 of your road trip in Sicily, your travel plans include 3 stops at the most scenic, wondrous, and interesting places in the region. Casa Santa, Agrigento, and Scavuzzo are on today's agenda. In the evening, you’ll end up in Palermo, where you will stay for 1 night.

After soaking in Trapani’s unique atmosphere, jump into the car with a full heart and drive in the direction of your next destination: Casa Santa. Expect your car journey to take a minimum of 30 min. When you arrive in Casa Santa, it's time to take a break from the road.

Enjoy sightseeing at your own pace and allow yourself time to explore the beautiful surroundings. Take your self-guided tour to Tower Of King Federico (bell Tower Of The Mother Church), an increasingly popular monument that everyone visiting Casa Santa should see.

Continue your road trip and head to your next destination, Agrigento. This car ride takes around 2 hours 30 min.

When you're ready for some sights, head to Valle Dei Templi, a popular archeological site in Agrigento. Explore its picture-perfect features at your own pace before you continue your journey.

Once you're ready to continue your road trip, it's time to buckle up and drive, eagerly anticipating your arrival in Scavuzzo. This drive usually takes around 20 min, without any stops or traffic disruptions.

Scala Dei Turchi is an often recommended rock formation we recommend visiting today. Discover its mesmerizing features before continuing your self-guided tour.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Palermo. Palermo offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

Indulge in a memorable dining experience at one of Palermo's most popular restaurants, and connect with friendly locals for a true cultural experience.

Enjoy a delicious meal at Osteria Mercede, a highly-rated dining destination in Palermo. If you're eager to try something different, consider Trattoria Del Massimo, another top spot with a tantalizing menu. You might also want to secure a reservation at Grand Hotel Piazza Borsa. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Palermo this evening.

Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, Spina Bar Palermo stands out as an excellent choice for a post-dinner cocktail. Alternatively, Torrefazione Castagnetta Massimiliano (gelateria) offers an ideal atmosphere to enjoy the pleasures of the night. Monkey Pub is also a great option that provides a perfect setting for a relaxing evening.

Celebrate another amazing day of your road trip adventure in Sicily!

Day4

Day 4

Palermo - Departure day
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Catacombe dei Cappuccini
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Day 4 of your road trip in Sicily is your departure day. This is your chance to catch a last glimpse of Palermo before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, we recommend visiting Catacombe Dei Cappuccini, a photogenic cemetery before you head out.

Before you conclude your road trip in Sicily, drop by another restaurant for a last chance at a memorable dining experience in Palermo.

If you're in the mood for something new, try Ristorantino Sobremesa, another premier location with a delectable menu.

You’ll then say farewell to Palermo. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Sicily!

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Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.

Personalize your itinerary

Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.

Easily make changes

Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.

Enjoy seamless planning

With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.

Explore with confidence

From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

Secure your spot

Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.

Get instant confirmation

Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.

Personalize your itinerary

Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.

Easily make changes

Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.

Enjoy seamless planning

With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.

Explore with confidence

From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

We guarantee

Your trip is protected, personalized, and priced right. No surprises, no stress.

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