4-Day Sicily Self-Drive Road Trip With Itinerary from Palermo to Cefalù

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Photo of Palermo, Sicily, Italy. Seafront view.
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Experience the freedom of the open road in Sicily as you embark on an unforgettable 4-day road trip! This experience caters to every traveler, featuring destinations like Palermo, Cefalù, Agrigento, and Isabella.

This perfectly planned road trip itinerary in Sicily takes you through some of the best places to see in the country. You will spend 2 nights in Palermo and 1 night in Cefalù. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Sicily. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Palermo, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Sicily on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Sicily. Valle Dei Templi and Palermo Cathedral are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Quattro Canti, learn more about the unique Norman Palace, and immerse yourself in the vibrant atmosphere of Catacombe Dei Cappuccini.

As you hit the open road and drive through Palermo, Cefalù, Agrigento, and Isabella, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Sicily. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Sicily.

Throughout your road trip in Sicily, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Sicily.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Sicily fill up quickly, so book your spot early. Select a date and start planning your road trip in Sicily today!

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Driver’s age is 30 - 65
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Itinerary summary

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Days
Destination
Attractions
Overnight
Day
City & Overnight
Attractions
Foro Italico
Norman PalacePalermo CathedralQuattro CantiFontana PretoriaCefalù BeachCathedral of Cefalù
Valle dei TempliTemple of HeraclesScala dei TurchiBasilica San Calogero
Catacombe dei Cappuccini

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Day 1

Day 1

  • Palermo - Arrival day
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  • Foro Italico
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Say hello to Palermo! Your exciting road trip through Italy is just about to start. Navigating the top places to see in the region is a breeze with a car. The rental vehicle of your choice will be ready for pickup upon your arrival in the city. You will stay in Palermo for 1 night before you continue your adventure!

Palermo is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Foro Italico, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Find your way to your hotel in Palermo. We recommend choosing a hotel in a central location for easy exploring. Check-in typically starts between 2 and 4 PM at hotels in Italy. Settle in and make plans for the evening.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Palermo, it's often a good idea to reserve a table in advance.

Dine in style at Cotto e Bollito, a top recommendation for dinner tonight. Or, for a change of pace, Bebop boasts a menu that's sure to impress. Also, be sure to check out Eremiti Restaurant. Known as a local hotspot, it’s a great choice for tonight in Palermo.

Extend your evening after a delightful meal by visiting Malox Cult, which offers the perfect atmosphere for a night out. Moreover, Ai Giudici is another popular option for a drink or two. Likewise, Bar Italico also provides a great ambiance for reminiscing about the day and raising a toast to your vacation.

Raise a toast to the start of your 4-day road trip in Sicily!

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Day 2

Day 2

  • Palermo
  • Cefalù
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Drive 72 km, 1 hour 45 min

  • Norman Palace
  • Palermo Cathedral
  • Quattro Canti
  • Fontana Pretoria
  • Cefalù Beach
  • Cathedral of Cefalù
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Experience an unparalleled adventure on day 2 of your road trip in Sicily. This exciting part of your journey invites you to discover the renowned landmarks in 2 vibrant destinations - Palermo and Cefalù. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Cefalù. You will spend 1 night here for some well-deserved relaxation.

Start by visiting Norman Palace, a prime spot to begin your journey. This breathtaking palace is sure to impress. Next on your list is Palermo Cathedral, another must-visit landmark and notable church renowned for its stunning features.

While exploring and sightseeing, take time to savor the culture of Palermo by sampling some local delicacies. When you’re ready for more sightseeing, head to Quattro Canti. This history-steeped public square is an essential place to visit for anyone looking for the full Palermo experience. We also recommend visiting Fontana Pretoria, an increasingly popular monument. Nearby, you'll also find Spiaggia Di Cefalù, ready to add charm to your journey. End your self-guided sightseeing tour with a stop at Cefalù Cathedral and wrap up your day with its enchanting appeal.

When you’re done exploring for the day, you’ll drive to your hotel in Cefalù. Check in and spend some time relaxing before you head out to tour the town.

As you explore more of Cefalù, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Make sure to reserve a table at Hotel Le Calette, an iconic dining spot in Cefalù. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Ristorante La Brace Cefalù, a popular restaurant in Cefalù. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Sicilian Food & Drink, a hidden gem nestled in Cefalù. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, Emme Café stands out as an excellent choice for a post-dinner cocktail.

Raise your glass to another unforgettable day in Sicily!

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Day 3

Day 3

  • Cefalù
  • Palermo
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Drive 307 km, 5 hours 11 min

  • Valle dei Templi
  • Temple of Heracles
  • Scala dei Turchi
  • Basilica San Calogero
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Dive into day 3 of your remarkable road trip in Sicily. Today you will explore Agrigento, Scavuzzo, and Isabella, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Palermo. You’ll stay here for 1 night.

A blend of fun adventures, scenic views, and photo-friendly spots await you in Cefalù on today’s itinerary. First up is the well-known archeological site, Valle Dei Templi. Afterward, continue to Temple Of Heracles, an archeological site every traveler should visit.

As you explore Cefalù’s charming streets, take in the lively atmosphere and get to know the character of the city. Next, make your way to Scala Dei Turchi. This locally appreciated rock formation is an essential stop. Following that, head to Basilica San Calogero, another must-visit site that will enhance your experience.

At the end of the day, you will drive to Palermo, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Palermo. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Don’t miss out on dining at Osteria Mercede, a top-rated dining destination in Palermo. If you're in the mood to try something new, consider Trattoria Del Massimo, another top spot with a mouthwatering menu. You might also want to secure a reservation at Grand Hotel Piazza Borsa. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Palermo this evening.

Cap off your dinner by heading to Spina Bar Palermo, ideal for a leisurely evening with a drink in hand. Torrefazione Castagnetta Massimiliano (gelateria) is another bar that offers an enjoyable setting. Similarly, Monkey Pub is also a popular place to go on a night out, perfect for relaxing and socializing.

Celebrate another amazing day of your road trip adventure in Sicily!

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Day 4

Day 4

  • Palermo - Departure day
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  • Catacombe dei Cappuccini
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Day 4 of your road trip in Sicily is your departure day. This is your chance to catch a last glimpse of Palermo before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, begin at Catacombe Dei Cappuccini. This well-known cemetery is a popular place to see in the city.

As your final day in Sicily unfolds, enjoy a last-minute shopping spree in Palermo's best shopping area. Enjoy finding the perfect gift or keepsake to remind you of your wonderful trip to Sicily.

Before you conclude your road trip in Sicily, drop by another restaurant for a last chance at a memorable dining experience in Palermo.

If you're eager to try something different, consider Ristorantino Sobremesa, another top spot with a tantalizing menu.

You’ll then say farewell to Palermo. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Sicily!

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