4-Day Sicily Self-Drive Road Trip With Itinerary from Palermo to Agrigento and surrounding area

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Experience the freedom of the open road in Sicily as you embark on an unforgettable 4-day road trip! This experience caters to every traveler, featuring destinations like Palermo, Agrigento, Monreale, and Isola delle Femmine.

This perfectly planned road trip itinerary in Sicily takes you through some of the best places to see in the country. You will spend 2 nights in Palermo and 1 night in Agrigento. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Sicily. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Palermo, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Sicily on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Sicily. Valle Dei Templi and Palermo Cathedral are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Cattedrale Di Monreale, learn more about the unique Quattro Canti, and immerse yourself in the vibrant atmosphere of Norman Palace.

As you hit the open road and drive through Palermo, Agrigento, Monreale, and Isola delle Femmine, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Sicily. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Sicily.

Throughout your road trip in Sicily, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Sicily.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Sicily fill up quickly, so book your spot early. Select a date and start planning your road trip in Sicily today!

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Driver’s age is 30 - 65
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Itinerary summary

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Days
Destination
Attractions
Overnight
Day
City & Overnight
Attractions
Quattro Canti
Norman PalacePalermo CathedralOrto botanico di PalermoCatacombe dei Cappuccini
Scala dei TurchiValle dei TempliCattedrale di MonrealeMonumento alla Strage di Capaci
Foro Italico

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Day 1

Day 1

  • Palermo - Arrival day
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  • Quattro Canti
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Your road trip adventure in Sicily begins as soon as you reach Palermo and pick up your car. You’ll stay in Palermo for 1 night and explore the best things to see and do, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.

Palermo is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Quattro Canti, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Find your way to your hotel in Palermo. We recommend choosing a hotel in a central location for easy exploring. Check-in typically starts between 2 and 4 PM at hotels in Italy. Settle in and make plans for the evening.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Palermo, it's often a good idea to reserve a table in advance.

Make sure to reserve a table at Cotto e Bollito, an iconic dining spot in Palermo. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Bebop, a popular restaurant in Palermo. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Eremiti Restaurant, a hidden gem nestled in Palermo. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

If you’re not ready to end the night just yet, Malox Cult offers a perfect venue to relax and savor a drink. Similarly, Ai Giudici is well-suited for those looking to unwind in a social setting. Bar Italico is another excellent spot to enjoy a nightcap after a delightful meal.

Raise a toast to the start of your 4-day road trip in Sicily!

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Day 2

Day 2

  • Palermo
  • Agrigento
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Drive 137 km, 2 hours 31 min

  • Norman Palace
  • Palermo Cathedral
  • Orto botanico di Palermo
  • Catacombe dei Cappuccini
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On day 2 of your exciting self-drive vacation in Sicily, you’ll soak in the magnificence of 1 destination, Palermo. When you’re not sightseeing, take time to relax at your selected hotel in Agrigento, where you’ll be staying for 1 night.

Enjoy the perfect balance of relaxation and exploration in Palermo today. One of the most popular attractions included on the itinerary is Norman Palace. This picture-perfect palace will help you start your sightseeing on top. Then, take a leisurely stroll to Palermo Cathedral and learn what makes this picture-perfect church unique.

Throughout the day, make sure to take breaks to appreciate the surroundings. Next up, visit the often recommended Orto Botanico Di Palermo. After exploring the botanical garden, head to Catacombe Dei Cappuccini. This captivating cemetery is a highlight in Palermo.

When you’re done exploring for the day, you’ll drive to your hotel in Agrigento. Check in and spend some time relaxing before you head out to tour the city.

After a day of adventure, treat yourself to an exquisite dinner at one of Agrigento's best restaurants.

Savor the flavors at Ambasciata di Sicilia, a top pick for dinner tonight. Alternatively, Le Cuspidi beckons with its unique menu offerings. Also, consider Yellove RistoVintage. With its consistent customer satisfaction, it’s an excellent option for dining in Agrigento tonight.

Celebrate another amazing day of your road trip adventure in Sicily!

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Day 3

Day 3

  • Agrigento
  • Palermo
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Drive 212 km, 3 hours 37 min

  • Scala dei Turchi
  • Valle dei Templi
  • Cattedrale di Monreale
  • Monumento alla Strage di Capaci
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Embark on another extraordinary experience on day 3 of your road trip in Sicily. Today, you will make 4 stops and experience some of the highlights of Scavuzzo, Agrigento, Monreale, and Isola delle Femmine. At the end of the day, you will enjoy the comforts of a top-rated hotel in Palermo, which will be your home away from home for 1 night.

Today’s agenda in Agrigento includes a rock formation, an archeological site, a church, a monument and much more! Scala Dei Turchi is must-visit rock formation and a great starting point for the day. Next, continue your journey to Valle Dei Templi, a popular archeological site, located just a leisurely stroll away. Next, head to Cattedrale Di Monreale, a historic church, also available for your discovery today.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Palermo. Palermo offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As dinnertime approaches, it's time to head out for a bite to eat in Palermo. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Get ready for an unforgettable culinary journey in Palermo by reserving a table at Buatta Cucina Popolana. Renowned as a Bib Gourmand restaurant, it offers an exceptional sicilian menu. For a different taste experience, head to Mec Restaurant, recognized for its delicious sicilian and contemporary dishes. This 1-star Michelin restaurant consistently impresses guests, ensuring a memorable addition to your holiday. Looking for another option? Make sure to visit Gagini Restaurant, a local favorite known for its delightful creative and contemporary cuisine in Palermo. Nestled in the heart of the city, this restaurant with 1 Michelin star is an ideal choice for discerning creative and contemporary foodies seeking culinary excellence.

After your meal, keep the night alive at a bar like Spina Bar Palermo, known for its lively atmosphere. Torrefazione Castagnetta Massimiliano (gelateria) is another top recommendation that provides the perfect setting with well-crafted drinks and a welcoming ambiance. Similarly, Monkey Pub offers an excellent atmosphere for those looking to amp up the evening.

Take some time to reflect on your day and savor another beautiful night in Sicily.

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Day 4

Day 4

  • Palermo - Departure day
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  • Foro Italico
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Day 4 of your road trip in Sicily is your departure day. This is your chance to catch a last glimpse of Palermo before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, begin at Foro Italico. This up-and-coming park is a popular place to see in the city.

Make the most of your final day in Sicily by visiting Palermo’s iconic markets and shopping establishments. Secure the perfect souvenirs for your family and friends back home or buy yourself a remembrance of your amazing experience in Sicily.

Before you conclude your road trip in Sicily, drop by another restaurant for a last chance at a memorable dining experience in Palermo.

Enjoy a lovely meal at Splendid Hotel la Torre, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Ristorantino Sobremesa is another top choice with a popular menu.

You’ll then say farewell to Palermo. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Sicily!

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