4-Day Sicily Self-Drive Road Trip With Itinerary from Palermo traveling east to Syracuse
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Experience the freedom of the open road in Sicily as you embark on an unforgettable 4-day road trip! This experience caters to every traveler, featuring destinations like Palermo, Syracuse, and Agrigento.
This perfectly planned road trip itinerary in Sicily takes you through some of the best places to see in the country. You will spend 2 nights in Palermo and 1 night in Syracuse. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!
With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Sicily. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.
Upon arriving in Palermo, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Sicily on your own terms.
An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Sicily. Valle Dei Templi and Palermo Cathedral are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Quattro Canti, learn more about the unique Norman Palace, and immerse yourself in the vibrant atmosphere of Neapolis Archaeological Park.
As you hit the open road and drive through Palermo, Syracuse, and Agrigento, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Sicily. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Sicily.
Throughout your road trip in Sicily, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Sicily.
This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.
The best services in Sicily fill up quickly, so book your spot early. Select a date and start planning your road trip in Sicily today!
Itinerary summary
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Day 1
- Palermo - Arrival day
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- Quattro Canti
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Welcome to Palermo, the perfect starting point for your road trip in Italy! Pick up your rental car and let the adventure begin. You will spend 1 night immersing yourself in Palermo's charm before embarking on the next leg of your journey.
Palermo is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Quattro Canti or taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.
Make your way to your chosen hotel. Check-in typically starts between 2 and 4 PM in Palermo. Make yourself at home and enjoy some downtime before heading out again.
As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Palermo, it's often a good idea to reserve a table in advance.
Enjoy a delicious meal at Cotto e Bollito, a top-rated dining destination in Palermo. If you're in the mood to try something new, consider Bebop, another top spot with a mouthwatering menu. You might also want to secure a reservation at Eremiti Restaurant. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Palermo this evening.
Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, Malox Cult stands out as an excellent choice for a post-dinner cocktail. Alternatively, Ai Giudici offers an ideal atmosphere to enjoy the pleasures of the night. Bar Italico is also a great option that provides a perfect setting for a relaxing evening.
Raise a toast to the start of your 4-day road trip in Sicily!
Day 2
- Palermo
- Syracuse
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Drive 266 km, 3 hours 25 min
- Catacombe dei Cappuccini
- Norman Palace
- Palermo Cathedral
- Foro Italico
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Dive into day 2 of your remarkable road trip in Sicily. Today you will explore Palermo, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Syracuse. You’ll stay here for 1 night.
Brace yourself for today’s incredible lineup of attractions in Palermo, featuring picturesque spots, historic treasures, and religious landmarks. Start at Catacombe Dei Cappuccini, an interesting cemetery in the city. Then, head to Norman Palace and soak in the ambiance of this historic palace.
There are many interesting places to see in Palermo and when you are ready for more, go to Palermo Cathedral. This is one of the city’s most notable spots. After exploring the church, visit the locally appreciated Foro Italico.
At the end of the day, you will drive to Syracuse, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.
As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Syracuse. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.
Experience a harmony of flavors at Cortile Spirito Santo in Syracuse by securing a reservation in advance. Known for its 1-star Michelin status, Cortile Spirito Santo offers a delightful variety of dishes highlighting its delicious creative and modern menu. If you're looking to mix things up, Dock Café Restaurant offers an enticing alternative with its varied menu.
Continue the enjoyment post-dinner at Barcollo, a cherished local gathering spot renowned for its welcoming atmosphere. Similarly, Bar Pasticceria Midolo offers a vibrant space for indulging in well-crafted drinks and engaging conversation. You may also want to check out Boats. This bar is a favorite among both locals and visitors looking for a delightful evening out filled with laughter and fun.
As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in Sicily.
Day 3
- Syracuse
- Agrigento
- Palermo
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Drive 353 km, 4 hours 49 min
- Temple of Apollo
- Ear of Dionysius
- Neapolis Archaeological Park
- Valle dei Templi
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Experience an unparalleled adventure on day 3 of your road trip in Sicily. This exciting part of your journey invites you to discover the renowned landmarks in 2 vibrant destinations - Syracuse and Agrigento. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Palermo. You will spend 1 night here for some well-deserved relaxation.
Set out on a day brimming with fun adventures, breathtaking views, and photo-friendly spots. Start at the notable Temple Of Apollo, a culturally significant archeological site in Syracuse. Next, go to Ear Of Dionysius.
After visiting Temple Of Apollo and Ear Of Dionysius, take time to explore Syracuse's streets and absorb its charm. Continue your sightseeing by heading to Neapolis Archaeological Park. This UNESCO world heritage-listed archeological site offers a unique experience.
When you’ve had your share of Syracuse, prepare for your next destination. Admire the views and listen to some good music as you drive in the direction of Agrigento. Your travel time is around 2 hours 27 min.
Head to Valle Dei Templi, a notable archeological site in Agrigento. Explore its stunning features at your own pace before you continue your journey.
After soaking up all the sights of today's itinerary, you'll be ready to hit the road in the direction of your accommodation in Palermo. Palermo offers plenty of top-rated hotels and other places to stay on any travel budget. Take some time to relax before you head out to explore.
After a day of adventure, treat yourself to an exquisite dinner at one of Palermo's best restaurants.
Treat yourself to an extraordinary dining experience at Buatta Cucina Popolana, a Bib Gourmand restaurant offering an incredible sicilian menu. Alternatively, if your taste buds call for something different, Mec Restaurant is one of the best restaurants for sicilian and contemporary cuisine in Palermo. This 1-star Michelin-awardee earns consistently high praises from guests. We also recommend checking out the menu at Gagini Restaurant. As a top-rated establishment with 1 Michelin star, it is an ideal choice for creative and contemporary cuisine in the city.
Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, Spina Bar Palermo stands out as an excellent choice for a post-dinner cocktail. Alternatively, Torrefazione Castagnetta Massimiliano (gelateria) offers an ideal atmosphere to enjoy the pleasures of the night. Monkey Pub is also a great option that provides a perfect setting for a relaxing evening.
Take some time to reflect on your day and savor another beautiful night in Sicily.
Day 4
- Palermo - Departure day
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- Garden Zisa
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Day 4 of your road trip in Sicily is your departure day. This is your chance to catch a last glimpse of Palermo before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.
Make the most of your final day in Sicily by visiting Palermo’s iconic markets and shopping establishments. Secure the perfect souvenirs for your family and friends back home or buy yourself a remembrance of your amazing experience in Sicily.
Bring your curiosity for today’s adventure around Palermo. Some of the city’s most loved attractions await. Giardino Della Zisa is the perfect place to start. This park is one of the most frequently visited places to visit in Palermo.
Before you conclude your road trip in Sicily, drop by another restaurant for a last chance at a memorable dining experience in Palermo.
Treat yourself to a delightful dinner at Splendid Hotel la Torre, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Ristorantino Sobremesa? It's another excellent option with a diverse menu.
You’ll then say farewell to Palermo. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Sicily!
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