4-Day Italy Self-Drive Road Trip With Itinerary from Pescara traveling west to Rome

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View of the Pescara city hall and surrounding buildings, Pescara, Italy.
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Experience the freedom of the open road on an unforgettable 4-day road trip in Italy! Embark on a self-drive tour that caters to every traveler, featuring destinations like Pescara, Rome, and Tivoli.

This perfectly planned road trip itinerary takes you through some of the best places to see in Italy. You will spend 2 nights in Pescara and 1 night in Rome. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Pescara, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Trevi Fountain and Colosseum are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Pantheon, learn more about the unique Piazza Navona, and immerse yourself in the vibrant atmosphere of Roman Forum.

As you hit the open road and drive through Pescara, Rome, and Tivoli, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.

Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!

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Driver’s age is 30 - 65
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Pick-up: 10:00
Drop-off: 10:00

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Day 1

Day 1

  • Pescara - Arrival day
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  • Locomotiva FS 740351
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Your road trip adventure in Italy begins as soon as you reach Pescara and pick up your car. You’ll stay here for 1 night and explore what to see in Pescara, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.

Pescara is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Locomotiva Fs 740.351, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

As afternoon approaches, head to your chosen hotel in Pescara. Check-in typically starts around 2 to 4 PM at hotels in Italy. We recommend staying at a central location for easy access to key areas in the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Pescara, it's often a good idea to reserve a table in advance.

Treat yourself to a delicious dinner at Taverna 58, an excellent option for tonight's dining. Looking for something different? Ristorante Carlo Ferraioli offers a tantalizing alternative with its diverse menu. And don’t miss Sesamo Nero. Known for great service, it’s a fantastic choice for tonight in Pescara.

To truly maximize your evening out, consider visiting Posa Caffè Pescara after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to Bar Mixer, another bar with an inviting ambiance. Similarly, Temple Bar Irish Pub also offers a great atmosphere, ensuring a night filled with enjoyment and relaxation.

Raise a toast to the start of your 4-day road trip in Italy!

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Day 2

Day 2

  • Pescara
  • Rome
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Drive 213 km, 3 hours 15 min

  • Colosseum
  • Roman Forum
  • Trevi Fountain
  • Piazza Navona
  • Pantheon
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Your itinerary for day 2 of your road trip in Italy includes 1 stop and features some of the highlights of Rome. At the end of the day, enjoy the comforts of a top-rated hotel in Rome, where you'll spend 1 night.

Make a stop at Colosseum. This globally renowned archeological site is a must-visit for travelers looking for a unique holiday experience. Make your way to Roman Forum located in Pescara for another exciting encounter.

Next, immerse yourself in the setting of Trevi Fountain. Its masterful features will captivate you. After the monument, continue your tour of the city with a visit to Piazza Navona. Visitors usually appreciate the enchanting features of this public square. Next up is Pantheon, a highly recommended monument.

When you’re done exploring for the day, you’ll drive to your hotel in Rome. Check in and relax before you head out to tour the city.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Rome. Enjoy a relaxing evening as you savor delicious local cuisine.

Enjoy a delicious meal at La Bottega Roma, a top-rated dining destination in Rome. If you're in the mood to try something new, consider Pasta In Corso, another top spot with a mouthwatering menu. You might also want to secure a reservation at Trattoria Vecchia Roma. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Rome this evening.

After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at La Botticella Of Poggi Giovanni, a well-loved spot among locals and tourists. Or, head to Almalu Trastevere. This bar boasts a welcoming environment that is perfect for winding down. You could also continue your night at Bar Viminale Di Pepi Maurilio, another top-rated place in the area.

Raise your glass to another unforgettable day in Italy!

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Day 3

Day 3

  • Rome
  • Pescara
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Drive 218 km, 3 hours 4 min

  • Hadrian's Villa
  • Villa d'Este
  • Gregorian Bridge
  • Villa Gregoriana
  • Grande Cascata di Tivoli
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Experience an unparalleled adventure on day 3 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 place, which are Tivoli. At the end of the day, you will retreat to the hotel of your choice in Pescara, where will spend 1 night.

One of the most locally appreciated attractions included on the itinerary is Hadrian's Villa. This breathtaking archeological site will help you start your sightseeing on top. Then, take a leisurely stroll to Villa D'este and learn what makes this enchanting palace unique.

Throughout the day, make sure to take breaks to appreciate the surroundings. Next up, visit the locally appreciated Gregorian Bridge. After exploring the monument, head to Villa Gregoriana. This beloved park is a highlight in Rome. As your day continues, stop by Grande Cascata Di Tivoli, known for its romantic features.

At the end of the day, you will drive to Pescara, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a day of adventure, treat yourself to an exquisite dinner at one of Pescara's best restaurants.

Make sure to reserve a table at Ciacco, an iconic dining spot in Pescara. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Bar Sara, a popular restaurant in Pescara. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Ristorante Franco, a hidden gem nestled in Pescara. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Round off your dining experience by visiting Bar Napoli, a prime location for a drink. Alternatively, explore the distinctive characteristics of Bar Supermarket, a bar catering to every mood and preference. Post Bar likewise offers a unique atmosphere, perfect for a memorable night out.

Relax and recharge in preparation for another adventurous day in Italy!

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Day 4

Day 4

  • Pescara - Departure day
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  • Parrocchia Spirito Santo
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Day 4 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Pescara before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, begin at Parrocchia Spirito Santo. This curiosity-inducing church is a hotspot among locals.

Take advantage of your accommodation's proximity to Pescara’s shopping district for some last-minute bargain hunting. Explore local shops for souvenirs to remember your trip or find unique gifts for loved ones.

Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Pescara.

If you're in the mood for something new, try La Taverna Antica, another premier location with a delectable menu.

You’ll then say farewell to Pescara. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!

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How it works

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Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

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Your trip is protected, personalized, and priced right. No surprises, no stress.

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